LOCUS       DAVMJI010000001       103355 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.001, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000001 DAVMJI010000000
VERSION     DAVMJI010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 103355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 103355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..103355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.001"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..309
                     /locus_tag="VYR58_000001"
     CDS             <1..309
                     /locus_tag="VYR58_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV3621243.1"
                     /translation="ENTILHSDQGWQYRHDSYHRFLESKGVQASMSRKGNSQDNGMME
                     SFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
                     "
     gene            complement(437..640)
                     /locus_tag="VYR58_000002"
     CDS             complement(437..640)
                     /locus_tag="VYR58_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3621244.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(633..1715)
                     /locus_tag="VYR58_000003"
     CDS             complement(633..1715)
                     /locus_tag="VYR58_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV3621245.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1841..2623)
                     /locus_tag="VYR58_000004"
     CDS             complement(1841..2623)
                     /locus_tag="VYR58_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV3621246.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2623..3966)
                     /locus_tag="VYR58_000005"
     CDS             complement(2623..3966)
                     /locus_tag="VYR58_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV3621247.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4065..5381)
                     /locus_tag="VYR58_000006"
     CDS             complement(4065..5381)
                     /locus_tag="VYR58_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV3621248.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5575..6801
                     /locus_tag="VYR58_000007"
     CDS             5575..6801
                     /locus_tag="VYR58_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV3621249.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGILGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7000..8574
                     /locus_tag="VYR58_000008"
     CDS             7000..8574
                     /locus_tag="VYR58_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV3621250.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8838..9626
                     /gene="codY"
                     /locus_tag="VYR58_000009"
     CDS             8838..9626
                     /gene="codY"
                     /locus_tag="VYR58_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV3621251.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9626..10201
                     /locus_tag="VYR58_000010"
     CDS             9626..10201
                     /locus_tag="VYR58_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV3621252.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10283..10368
                     /locus_tag="VYR58_000011"
     tRNA            10283..10368
                     /locus_tag="VYR58_000011"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10317..10319,aa:Leu,seq:aag)
     gene            10651..11781
                     /gene="ugpC"
                     /locus_tag="VYR58_000012"
     CDS             10651..11781
                     /gene="ugpC"
                     /locus_tag="VYR58_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV3621253.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(11928..12074)
                     /locus_tag="VYR58_000013"
     CDS             complement(11928..12074)
                     /locus_tag="VYR58_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621254.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            12282..13040
                     /locus_tag="VYR58_000014"
     CDS             12282..13040
                     /locus_tag="VYR58_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV3621255.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13128..13640
                     /locus_tag="VYR58_000015"
     CDS             13128..13640
                     /locus_tag="VYR58_000015"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV3621256.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13822..14766
                     /locus_tag="VYR58_000016"
     CDS             13822..14766
                     /locus_tag="VYR58_000016"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV3621257.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAARQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14775..15452
                     /locus_tag="VYR58_000017"
     CDS             14775..15452
                     /locus_tag="VYR58_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV3621258.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15550..16308
                     /locus_tag="VYR58_000018"
     CDS             15550..16308
                     /locus_tag="VYR58_000018"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV3621259.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16346..17851
                     /gene="lytC"
                     /locus_tag="VYR58_000019"
     CDS             16346..17851
                     /gene="lytC"
                     /locus_tag="VYR58_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV3621260.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18349..18867
                     /locus_tag="VYR58_000020"
     CDS             18349..18867
                     /locus_tag="VYR58_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV3621261.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            18997..19503
                     /locus_tag="VYR58_000021"
     CDS             18997..19503
                     /locus_tag="VYR58_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV3621262.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19503..19673
                     /locus_tag="VYR58_000022"
     CDS             19503..19673
                     /locus_tag="VYR58_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621263.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            19705..20937
                     /gene="clpX"
                     /locus_tag="VYR58_000023"
     CDS             19705..20937
                     /gene="clpX"
                     /locus_tag="VYR58_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV3621264.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            20946..21533
                     /locus_tag="VYR58_000024"
     CDS             20946..21533
                     /locus_tag="VYR58_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV3621265.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHAPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21544..21924
                     /locus_tag="VYR58_000025"
     CDS             21544..21924
                     /locus_tag="VYR58_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV3621266.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            21976..22866
                     /gene="rapZ"
                     /locus_tag="VYR58_000026"
     CDS             21976..22866
                     /gene="rapZ"
                     /locus_tag="VYR58_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV3621267.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22863..23840
                     /locus_tag="VYR58_000027"
     CDS             22863..23840
                     /locus_tag="VYR58_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV3621268.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23837..24748
                     /gene="whiA"
                     /locus_tag="VYR58_000028"
     CDS             23837..24748
                     /gene="whiA"
                     /locus_tag="VYR58_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV3621269.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24782..25750)
                     /locus_tag="VYR58_000029"
     CDS             complement(24782..25750)
                     /locus_tag="VYR58_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV3621270.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25886..26743
                     /locus_tag="VYR58_000030"
     CDS             25886..26743
                     /locus_tag="VYR58_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV3621271.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26730..27509
                     /locus_tag="VYR58_000031"
     CDS             26730..27509
                     /locus_tag="VYR58_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV3621272.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27533..28885
                     /locus_tag="VYR58_000032"
     CDS             27533..28885
                     /locus_tag="VYR58_000032"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV3621273.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVNYYVDTITDVVRAEIGID
                     "
     gene            28959..29333
                     /locus_tag="VYR58_000033"
     CDS             28959..29333
                     /locus_tag="VYR58_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV3621274.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29335..30183
                     /locus_tag="VYR58_000034"
     CDS             29335..30183
                     /locus_tag="VYR58_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV3621275.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30449..31216
                     /locus_tag="VYR58_000035"
     CDS             30449..31216
                     /locus_tag="VYR58_000035"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV3621276.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWIDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31228..32412
                     /locus_tag="VYR58_000036"
     CDS             31228..32412
                     /locus_tag="VYR58_000036"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV3621277.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32409..34280
                     /locus_tag="VYR58_000037"
     CDS             32409..34280
                     /locus_tag="VYR58_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV3621278.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKSDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLNKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMSRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34423..35607)
                     /gene="mntE"
                     /locus_tag="VYR58_000038"
     CDS             complement(34423..35607)
                     /gene="mntE"
                     /locus_tag="VYR58_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV3621279.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPILEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            35911..38607
                     /locus_tag="VYR58_000039"
     CDS             35911..38607
                     /locus_tag="VYR58_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV3621280.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAMDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     LLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFASDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38620..39411
                     /gene="yghU"
                     /locus_tag="VYR58_000040"
     CDS             38620..39411
                     /gene="yghU"
                     /locus_tag="VYR58_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV3621281.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKVANRPAVKRGLEVTYTEIK"
     gene            39527..39937
                     /locus_tag="VYR58_000041"
     CDS             39527..39937
                     /locus_tag="VYR58_000041"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV3621282.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            39949..41544
                     /locus_tag="VYR58_000042"
     CDS             39949..41544
                     /locus_tag="VYR58_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621283.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            41711..41875
                     /locus_tag="VYR58_000043"
     CDS             41711..41875
                     /locus_tag="VYR58_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV3621284.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41954..42682
                     /gene="yaaA"
                     /locus_tag="VYR58_000044"
     CDS             41954..42682
                     /gene="yaaA"
                     /locus_tag="VYR58_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV3621285.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42960..43508)
                     /locus_tag="VYR58_000045"
     CDS             complement(42960..43508)
                     /locus_tag="VYR58_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV3621286.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            43829..44317
                     /locus_tag="VYR58_000046"
     CDS             43829..44317
                     /locus_tag="VYR58_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV3621287.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            44314..45501
                     /locus_tag="VYR58_000047"
     CDS             44314..45501
                     /locus_tag="VYR58_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV3621288.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     CTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            45494..45718
                     /locus_tag="VYR58_000048"
     CDS             45494..45718
                     /locus_tag="VYR58_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV3621289.1"
                     /translation="MIDHFEIKVKDLQISGGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEV"
     gene            45875..47221
                     /gene="asnS"
                     /locus_tag="VYR58_000049"
     CDS             45875..47221
                     /gene="asnS"
                     /locus_tag="VYR58_000049"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV3621290.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            47374..47664
                     /locus_tag="VYR58_000050"
     CDS             47374..47664
                     /locus_tag="VYR58_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV3621291.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            47676..48146
                     /gene="ssbA"
                     /locus_tag="VYR58_000051"
     CDS             47676..48146
                     /gene="ssbA"
                     /locus_tag="VYR58_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV3621292.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            48178..48417
                     /locus_tag="VYR58_000052"
     CDS             48178..48417
                     /locus_tag="VYR58_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV3621293.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            48712..50112
                     /locus_tag="VYR58_000053"
     CDS             48712..50112
                     /locus_tag="VYR58_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV3621294.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            50114..50473
                     /locus_tag="VYR58_000054"
     CDS             50114..50473
                     /locus_tag="VYR58_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV3621295.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            50527..51276
                     /locus_tag="VYR58_000055"
     CDS             50527..51276
                     /locus_tag="VYR58_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV3621296.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            51266..51565
                     /locus_tag="VYR58_000056"
     CDS             51266..51565
                     /locus_tag="VYR58_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV3621297.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            51636..52571
                     /locus_tag="VYR58_000057"
     CDS             51636..52571
                     /locus_tag="VYR58_000057"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV3621298.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            52657..53169
                     /locus_tag="VYR58_000058"
     CDS             52657..53169
                     /locus_tag="VYR58_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV3621299.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            53206..53802
                     /locus_tag="VYR58_000059"
                     /pseudo
     CDS             53206..53802
                     /locus_tag="VYR58_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            53903..54097
                     /locus_tag="VYR58_000060"
     CDS             53903..54097
                     /locus_tag="VYR58_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV3621300.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVSKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(54143..55588)
                     /locus_tag="VYR58_000061"
     CDS             complement(54143..55588)
                     /locus_tag="VYR58_000061"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV3621301.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYIAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISLDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FRFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            55694..57316
                     /locus_tag="VYR58_000062"
     CDS             55694..57316
                     /locus_tag="VYR58_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV3621302.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            57519..59477
                     /locus_tag="VYR58_000063"
     CDS             57519..59477
                     /locus_tag="VYR58_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV3621303.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKSKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            59649..60605
                     /locus_tag="VYR58_000064"
     CDS             59649..60605
                     /locus_tag="VYR58_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621304.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDMSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFEGGKSVSG"
     gene            60609..61331
                     /locus_tag="VYR58_000065"
     CDS             60609..61331
                     /locus_tag="VYR58_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3621305.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGKKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARAYLKDAEIL
                     IFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            61488..62582
                     /locus_tag="VYR58_000066"
     CDS             61488..62582
                     /locus_tag="VYR58_000066"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV3621306.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            62590..63756
                     /locus_tag="VYR58_000067"
     CDS             62590..63756
                     /locus_tag="VYR58_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV3621307.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSIKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            63849..66947
                     /locus_tag="VYR58_000068"
     CDS             63849..66947
                     /locus_tag="VYR58_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV3621308.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKVLPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREKDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            66995..67612
                     /locus_tag="VYR58_000069"
     CDS             66995..67612
                     /locus_tag="VYR58_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV3621309.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKLVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            67623..68957
                     /locus_tag="VYR58_000070"
     CDS             67623..68957
                     /locus_tag="VYR58_000070"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV3621310.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            68967..69431
                     /locus_tag="VYR58_000071"
     CDS             68967..69431
                     /locus_tag="VYR58_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3621311.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKVIRLESPDELLSYFGMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            69428..69922
                     /locus_tag="VYR58_000072"
     CDS             69428..69922
                     /locus_tag="VYR58_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3621312.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVDLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            70003..71658
                     /gene="mltG"
                     /locus_tag="VYR58_000073"
     CDS             70003..71658
                     /gene="mltG"
                     /locus_tag="VYR58_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV3621313.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPAKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            71729..72211
                     /gene="greA"
                     /locus_tag="VYR58_000074"
     CDS             71729..72211
                     /gene="greA"
                     /locus_tag="VYR58_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV3621314.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(72562..72642)
                     /locus_tag="VYR58_000075"
                     /pseudo
     CDS             complement(72562..72642)
                     /locus_tag="VYR58_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            72764..73162
                     /locus_tag="VYR58_000076"
     CDS             72764..73162
                     /locus_tag="VYR58_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3621315.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            73620..74627
                     /locus_tag="VYR58_000077"
     CDS             73620..74627
                     /locus_tag="VYR58_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV3621316.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSVTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYAFWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            74702..74902
                     /locus_tag="VYR58_000078"
     CDS             74702..74902
                     /locus_tag="VYR58_000078"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV3621317.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            74937..75653
                     /gene="atpB"
                     /locus_tag="VYR58_000079"
     CDS             74937..75653
                     /gene="atpB"
                     /locus_tag="VYR58_000079"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV3621318.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLPYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            75667..76161
                     /gene="atpF"
                     /locus_tag="VYR58_000080"
     CDS             75667..76161
                     /gene="atpF"
                     /locus_tag="VYR58_000080"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV3621319.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            76161..76697
                     /locus_tag="VYR58_000081"
     CDS             76161..76697
                     /locus_tag="VYR58_000081"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV3621320.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            76712..78217
                     /locus_tag="VYR58_000082"
     CDS             76712..78217
                     /locus_tag="VYR58_000082"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV3621321.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            78233..79111
                     /locus_tag="VYR58_000083"
     CDS             78233..79111
                     /locus_tag="VYR58_000083"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV3621322.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            79197..80603
                     /gene="atpD"
                     /locus_tag="VYR58_000084"
     CDS             79197..80603
                     /gene="atpD"
                     /locus_tag="VYR58_000084"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV3621323.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            80614..81033
                     /locus_tag="VYR58_000085"
     CDS             80614..81033
                     /locus_tag="VYR58_000085"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV3621324.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(81078..82091)
                     /locus_tag="VYR58_000086"
     CDS             complement(81078..82091)
                     /locus_tag="VYR58_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV3621325.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            82235..83401
                     /locus_tag="VYR58_000087"
     CDS             82235..83401
                     /locus_tag="VYR58_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV3621326.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            83391..84620
                     /locus_tag="VYR58_000088"
     CDS             83391..84620
                     /locus_tag="VYR58_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV3621327.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            84766..85407
                     /locus_tag="VYR58_000089"
     CDS             84766..85407
                     /locus_tag="VYR58_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV3621328.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            85417..86046
                     /locus_tag="VYR58_000090"
     CDS             85417..86046
                     /locus_tag="VYR58_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV3621329.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            86059..86895
                     /locus_tag="VYR58_000091"
     CDS             86059..86895
                     /locus_tag="VYR58_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV3621330.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(87173..87520)
                     /locus_tag="VYR58_000092"
     CDS             complement(87173..87520)
                     /locus_tag="VYR58_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV3621331.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     ADTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(87631..89349)
                     /locus_tag="VYR58_000093"
     CDS             complement(87631..89349)
                     /locus_tag="VYR58_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV3621332.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNETAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            89583..89726
                     /locus_tag="VYR58_000094"
     CDS             89583..89726
                     /locus_tag="VYR58_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV3621333.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            89693..89908
                     /locus_tag="VYR58_000095"
     CDS             89693..89908
                     /locus_tag="VYR58_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV3621334.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            89895..90428
                     /locus_tag="VYR58_000096"
     CDS             89895..90428
                     /locus_tag="VYR58_000096"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV3621335.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKNLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            90768..91022
                     /locus_tag="VYR58_000097"
     CDS             90768..91022
                     /locus_tag="VYR58_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621336.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPIWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            91133..92212
                     /locus_tag="VYR58_000098"
     CDS             91133..92212
                     /locus_tag="VYR58_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV3621337.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDIVEPSRTVVEKIIPKLNIPEEEKKKKTSELAE
                     LISENVKVCYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNVTDKKLSSMT
                     TTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKEGSQEKL
                     AESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAYQKTVQQ
                     LTITTVRMLRKQWFPKQQPLLRRRL"
     gene            92170..92847
                     /locus_tag="VYR58_000099"
     CDS             92170..92847
                     /locus_tag="VYR58_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV3621338.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEP
                     TPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLASLVLGFF
                     KKKEDEK"
     gene            93071..93940
                     /locus_tag="VYR58_000100"
     CDS             93071..93940
                     /locus_tag="VYR58_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV3621339.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            94851..96047
                     /gene="tuf"
                     /locus_tag="VYR58_000101"
     CDS             94851..96047
                     /gene="tuf"
                     /locus_tag="VYR58_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV3621340.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            96501..97583
                     /locus_tag="VYR58_000102"
                     /pseudo
     CDS             96501..97583
                     /locus_tag="VYR58_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(97647..98729)
                     /locus_tag="VYR58_000103"
     CDS             complement(97647..98729)
                     /locus_tag="VYR58_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV3621341.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     SEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(98726..99703)
                     /locus_tag="VYR58_000104"
     CDS             complement(98726..99703)
                     /locus_tag="VYR58_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV3621342.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFRKSNDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            99936..100313
                     /locus_tag="VYR58_000105"
                     /pseudo
     CDS             99936..100313
                     /locus_tag="VYR58_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            100548..101939
                     /locus_tag="VYR58_000106"
     CDS             100548..101939
                     /locus_tag="VYR58_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV3621343.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKMEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEAAILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            102042..102119
                     /locus_tag="VYR58_000107"
                     /pseudo
     CDS             102042..102119
                     /locus_tag="VYR58_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            102195..103037
                     /locus_tag="VYR58_000108"
     CDS             102195..103037
                     /locus_tag="VYR58_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV3621344.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
BASE COUNT        30979 a        19088 c        23089 g        30199 t
ORIGIN      
        1 gagaatacga ttctccatag tgaccaaggc tggcaatacc gacacgattc ttatcatcgg
       61 ttcctagaga gtaagggagt tcaagcatcc atgtcacgca agggaaacag ccaagacaac
      121 ggtatgatgg aatctttctt tgggattctg aaatcggaaa tgttttacgg ttatgagaag
      181 tcgtttcagt cgcttaagca attggaacaa gctattgtag actatattga ttactacaac
      241 aataaacgaa ttaaggtaaa actaaaagga cttagtcctg tgcaatacag aactaaatcc
      301 ttcggataaa ttatttgtct aacttttggg gggcagtaca ttttaacact tgatactatg
      361 cgttttattg tgggaagatt ttcctcattt tctagtgaaa ttgaactttt tctaacatct
      421 tttgatagat gacttcttaa tcaattatca tttccattgt tgtttcttgg ggtttcatcc
      481 cttgtctttg ataaaagcgg agagcaccct cgttatcatt ccagacactt agggttagat
      541 tattgcagcc aatttcttta gcataatagc agaaaaatga caataaaata gcccctagat
      601 attttgaaag gaaagcatag gggctatata gtttaatcaa aataaagcaa atctttgctg
      661 gtgcttgtaa agaggtcgaa gccatccttg gtaacaacac cgcagtcttc aatacgaaca
      721 ccgactttac cagggatata gatacctggt tcaacagaga agcacatgcc ttcttcgatg
      781 accatgtcgt ttccttccat gatagatggg aattcatgga catccatacc gataccatgc
      841 ccgagacggt ggttgaagta ctcaccataa ccagcttttt cgatgacctc acgggcagcg
      901 cggtccactt catgagcagt cacacctggc ttgataaagt caagagcagc ttgttgggct
      961 tcaagagtca agttgtaaat atctttcttg aattggtctg gtttgccgac agcgactgta
     1021 cgagtcatat ctgacgcata gccattgacc agaacaccca ggtcaaagag gagaagagca
     1081 tcattttcaa ccttattagc tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc
     1141 aagaccatgg tatcaaagct catttcataa ccttcacgtt tcatggcaaa gtcgatttgt
     1201 gcgatgatat ctgtctcagt cttatcaaga gaaatattgt caaaaccaac atgaacagcc
     1261 ttgtcagcat aaagacctgc aaccatcatt ttttgcactt catcagctga tttgatgagg
     1321 cgcatgcgtt ggatacgagg agtgaggttg tcaaactcag cagtctcaaa aactgttttc
     1381 aaaccatggt atttggtcaa gatgagattg tcaaactcaa cagcgacacg tttgaagtca
     1441 agttgtggaa gagcatgttt gattttttgc catggatttt cagaatcgac atagcccact
     1501 actgggaagg aaacggtgct acttgcacgt tctacttcaa gagctgggac aaagaggaga
     1561 ggttcctgat ccgctaggac aaagaggaac atttggcgtt catggggatc actgtaaaaa
     1621 ccagtgaggt aattgattgt gacggggtca gatacgacag cgacgtctag tttttctgat
     1681 tcaagatatg ttaggatttg ttgtaattta gacatatgct accttctttc tacccctcta
     1741 ttttggcaaa aaatgagaga aaatgcaagg gagaagggta aaagaaaaga caaaaaactc
     1801 cgacaagata acggagttct ttgatatcat tttcctttgt ttaagaaaag tcagccttgc
     1861 ttttgacgtc actgtactct tcagcgattt cttggctgag aatgtcctca taggcaggga
     1921 gttggatgtc ctgaccatat ttcttcttga gggcagtagt aactaggcga taagccagat
     1981 tggcattacg agagaggata ggcccgtgga agtaggaacc aaagacattc ttataatgaa
     2041 ccccttcacc gaccttttct tcgttgtttc catttccata gacaacctgt cccagcggtt
     2101 tttggtcatc agagaggaag gtacgacctt ggtgattttc aaatccatag taggtttcat
     2161 cgaaatcttc attgtgaatc ttgatgtcac cgataaaacg gttattggtc tggttgagcg
     2221 tgtagtgtcc catgacccct agcccttcga tacgttttcc tgaagcttca acataatatt
     2281 gacccaatag ttggaaacca ccgcagatag ccagaactac accgtcgttt tggatgtagt
     2341 tgtcaatgct ctctttttta gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt
     2401 gaccaccacc gaaaaaggcg atgtcgtagt gattttcatc aaagtcatca tggagagaaa
     2461 cgatgtcaac ggtcacatgg gctcccagtt tttcagccac atacttgagc atgaggatgt
     2521 ttccattgtc cccgtaggta ttcatgagat ttccgtagag gtgggcaatg ttgagctgat
     2581 aggggtaatt gctatctttt gaggaaagtg aagtataaac cattagttca tctcctttct
     2641 aacaatctga cgactagcca gcagttcacg aaattccagc atggcagtat aagttgccag
     2701 aatataggca tgcttgcagt cttgattctc aatggtcttg agaacttgct ccagattact
     2761 cgtttcagtg attttctcag ctggatagcc agtcactcgg aggcgacgag cgatttcaga
     2821 atgacgaaca ccgccagcgt tgatttcagg aatgtccatg tcagtgattt gctcaaagtc
     2881 tgcatcccag atccagctag tgtcaattcc atctgcatag ttggcattaa ggaggacaga
     2941 taggctaaat ggataaggtg ctagtttgat catttcgata gcttgggttg caccgactgg
     3001 atttttaatc aagacaaggg tacattcctt gtcaccgata tgaaaggttt cttggcgtcc
     3061 aaagacagca cggctcttgt caaatccctg tttgatgagt tgggaatctg cgccgaggaa
     3121 acgggcgatg gccacagcag ctagggcgtt atagatatta tagagcccgc cgatttggat
     3181 accgtattct tggccgtcta tgacaaagcg agagcgattg ttggtcaact caaccagttt
     3241 tgtcaaacga tagtcgagat caggacgttt acatccacaa ccttcacaga tataggcacc
     3301 caagtttgca taggtattat gctcatattt gaggatgcct tggcagtcag gacagagaat
     3361 cccttcggta ttgtagtgag caagttgggc tggtcctttt tccaagtcaa aaccaaaata
     3421 ctctataggg tttggaatag ttggcttgta gaaaagtgga ctgtctccgt taaggagaac
     3481 agtagcagtt ggaacttttc gaatggcatc caatatcatg ttataggtag tatagatttc
     3541 accgaaacgg tccatctggt cacggaagat attagtaatg acaaaaagac taggctggat
     3601 atagtcacag atacgagata gactggcttc gtcaatttcg aggacggcaa tatttttccc
     3661 agtttttgaa gatttggctg ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc
     3721 gcttgggttg gttagaactt gaccataaac ctcttttaaa atgccgacag tgagggcagt
     3781 tgtcagggtt tttccatttg ttccagtgac aacgacaatc tcgtagttct tagctaggct
     3841 ttgtaaaata tctttatcaa attgaagggc gactttccct gggagcgtac ttccacgtcc
     3901 aagacggctt aaaacgaagt gggaagaacg cccagcaaga aggcccaaag tagtttttaa
     3961 gttcatgttt ctattatatc acaaaagagg gaaaagacag atttggtgtt tcgtagaagt
     4021 aaaaacagcc caaagagggc tgtcagttaa gatgagattt caacttaaat cgcaaacaag
     4081 tcattcaagt tctcagccaa ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa
     4141 ggaatcttgt tgtccatagc aacagtaatg atgttgatga tttcttgaga accttctgag
     4201 aagatgcttg caccaagaat ttcttttgtt tcagtattaa caacagcttt gaaagctccg
     4261 cgaaggtctc catttacgtg accacgaggc atggctgcaa cagggatttc tttcactgcg
     4321 tatggaagtt tcaaatcagc tgcttggctt tcagtcaaac caacttgtga aagtgcaggt
     4381 gtgatgaaca tagtatttgg cacattgaga cggtcctcaa gtgtgtagct gccatctcca
     4441 gcaaggtagc tgtaaacaac acggaagtca tcaagtgaaa tgtaagtaaa ttgaaggcca
     4501 ccgttgacat ctccaactgc aaagacacca ggaacgtttg tttgacagtg tttgtctact
     4561 ttaatagcac cacgttcagt tagttcaata tctgtatttt caagttgaag tggttctaca
     4621 tttggtttgc gtccagttgc gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt
     4681 acgacaagca cttggtcacc atcgtttttg atttcagtag tatggatatt ttgaagcaat
     4741 tcaataccgt cttcttccat gtattgttta gcaagagctg cgatggaagg ttctgcacga
     4801 ggtaggaatg tatccaaggc atctaggact gtaaccttgc ttcctagttt attgtaaagg
     4861 ccagcaaatt caagaccgat atttccgcca ccaaggactc caagtttttc aggcaattta
     4921 tccaagcttt ggatacctgt tgagtcaaag acgtttttgc ttgtagcaag tccagggatt
     4981 ggcaagacgt ttgaaacagc accagtgttg atgacgatag tttcagcagt caattcttgt
     5041 ttttcatcac cagcttggat ttcgatgact ttatttgaaa ggaagtgagc ttcagcatca
     5101 aagatattga cgccagtacc agcaacagtc gtatagtttt taccgttgag gcgaccagtg
     5161 atcgtgtttt tggtagcaat gacttcttca aaagacaagt ctttctcagc agcaaccagc
     5221 aaagttttag ttgggataca accgatgttg atacaagttc caccgtacat agctttgcta
     5281 cgttcaacga gggcaacttt tttgccagct gaagccaatt tacctgctag tgttttacca
     5341 gctttaccaa atccgataac gattaaatca taagttaaca tttagagttc ctcctattcg
     5401 catttcattc tagcacaaga aaaaaacttt tgcacaattc tgctacggaa aagacagaaa
     5461 aagataaaaa cgctttccag acaaaaaact agtaattttt tgacaagctt gataaactaa
     5521 aatcctatct atttttatat aagatagaaa aaatgttcga aaataggagg ttttatgaaa
     5581 tcgaatcgtt atattattgc ctttgctggg gtcattttac acttaatgct gggttcgact
     5641 tatgcttgga gtgtttatcg taaccctatt attgaaaaaa cgggatggga tcaggcttct
     5701 gttgcctttg cctttagtct agcaatcttt tgtttgggct tatcggctgc atttatgggg
     5761 cgtttggtag aaaaatttgg tccgagagtc atggggagtc tatctgcttt tctatacgca
     5821 ggtggaaata tcttaacagg atttgcaata gaccgtcagg aactgtggtt gttgtatcta
     5881 gcttatggca ttttaggtgg gcttggtttg ggagcaggct atattacccc tgtgtcaacg
     5941 attataaaat ggtttcctga taaacgtggt ctcgcaacag gtttagcgat tatggggttt
     6001 ggttttgctt ctttattgac tagtcccata gcgcaacatc tcatcgcagg ggtagggctt
     6061 gtagaaactt tttatatttt aggtgcaagt tactttatta tcatgctcct agcttcacaa
     6121 ttcattaagc gtccaaatga gcaagagctt gcaattttat ctgcttcagg gaaagaaaaa
     6181 acagactctc tgacgcaagg gatgactgca aatcaggctc taaaaagcaa tcggttttat
     6241 atgctttgga ttattttctt tatcaacata gcttgtggtt taggcttaat ttcagcggca
     6301 tcgccaatgg cacaggagat ggctggcttg tctacaagtc atgcagcagt aatggtgggt
     6361 attttgggga ttttcaatgg atttggtcgc ttgctctggg cgagtttgtc tgactatatc
     6421 ggtcgccctc taacctttag tatattactg cttgtcaatc ttttcttttc tctctcactt
     6481 tggctcttta cagattccgt tttatttgta gttgctatgt ctattttgat gacttgctat
     6541 ggagctggtt tttctttgat tccagcttat ctcagtgata tttttggaac caaggaattg
     6601 gccgctctgc atggttatat tttaacagct tgggcaatgg ctggtttagc gggacctatt
     6661 ttattagcag agacttataa aatggctcat tcgtacacac aaaccttgtt cgtttttctc
     6721 attttataca gtatcgcctt ggctttgtct tattatctag gtcgttcaat caaaaaagaa
     6781 agtcaaaaac cgcttacatg attttctgta gaaatggggc tatcttttgc tctggtcttg
     6841 tgttatacta gataggttgc aaagaaaaca gtacttttct tttgtggaaa agaagcaaca
     6901 cgattttata tctagttata tgaaaatacg tcataaaaag aaaagtataa actaagccct
     6961 atagggtggc ttcgcaccac ctttagaaag aagaataacg tgaaatttaa tgaattaaac
     7021 ttgtctgctg atttgctagc agaaattgaa aaagctggtt ttgtagaagc tagtcctatc
     7081 caagaacaaa ctattccttt ggcccttgaa ggcaaggatg ttatcggtca agctcagact
     7141 ggtacaggaa aaactgcagc ctttggcttg cctacccttg aaaaaatccg tacagaagaa
     7201 gcgactatcc aagctttggt catcgctcca actcgtgaac tagctgtcca aagtcaagaa
     7261 gaactcttcc gctttggtcg tagtaaggga gtcaaagtcc gttcagtata tggcggatca
     7321 agcattgaaa aacaaattaa ggctcttaaa tctggtgccc atatcgtggt gggaactcca
     7381 ggtcgcctct tggacttgat taaacgcaag gccttgaaat tacaagacat tgaaaccctt
     7441 atccttgacg aagcggatga aatgcttaac atgggcttcc ttgaagacat cgaagccatt
     7501 atttcccgtg tacctgagaa ccgtcaaact ttgcttttct cagcaactat gccagatgcc
     7561 atcaaacgta tcggtgttca gtttatgaaa gcccctgaac atgtcaagat tgcggctaag
     7621 gaattgacaa cagaattggt tgaccagtac tatatccgtg ttaaggaaca agaaaaattt
     7681 gacaccatga ctcgtctcat ggatgtggca caaccagaac tcgctattgt atttggtcgt
     7741 accaaacgcc gtgtggatga attgactcgt ggtttgaaaa ttcgtggctt ccgtgcagaa
     7801 ggaattcatg gcgacctaga ccaaaacaaa cgtcttcgtg tccttcgtga ctttaaaaat
     7861 ggcaatcttg atgttttggt tgcgacagac gttgcagcgc gtggtttgga tatttcaggt
     7921 gtgacccatg tctacaacta cgatattcca caagatcctg agagttatgt tcaccgtatc
     7981 ggtcgtacag gtcgtgctgg taagtcaggt caatctatta cttttgttgc tccaaacgaa
     8041 atgggttacc ttcaaatcat tgaaaacttg actaagaaac gcatgaaagg tctcaaacct
     8101 gcaagtgtag aagaatcctt ccaatcaaaa aaacaggtag ctctcaagaa aatcgaacgt
     8161 gattttgcag atgaaaccat tcgtgccaac tttgagaaat ttggtaagga tgctcgcaaa
     8221 ttggctgctg agtttactcc agaagaattg gcaatgtata tcttgagtct gacagtccaa
     8281 gacccagata gccttccaga agtggagatt gcacgtgaaa aaccactacc gtttaaacca
     8341 tcaggtaatg gtttcggtgg taaagctaag ggaggtcgtg gaggccgtcg tggggacgac
     8401 cgtcgagagc gtgatcgccg tggcaatggt cgccgtgatg agttcaaaaa aggaagtcgt
     8461 ggcaacgatc gttttgataa ggaaaaacgt taccgtaagg ataataaaaa accacgcaat
     8521 actttaagcg aaaagcaaac aggctttgtt attcgtaaca agggcgataa ataagaaaaa
     8581 gcggttcaaa atgaatcgct tttttatata aggagaccga atgtgaaaag acaaataaaa
     8641 ttattatatt atcttttata atgttatgat acacaaaaat aggcaacttg tcaatagaaa
     8701 aggaacaatt taattaaaaa tattctggtt tttaattaaa ttgtaagtca atgcaagtca
     8761 ataaggaatt ttcagataat tattgaaaaa gagacgtttt tatgttataa tgatagcgat
     8821 taaattcgag gtgaaaaatg gcacatttat tagaaaaaac tagaaaaatt acatcaattt
     8881 tgaaacgctc agaggagcag ttgcaggatg agctccctta caacgctatt acgcgtcagt
     8941 tagcggatat tattcattgc aatgcctgca ttatcaatag taagggacgt ctgcttggct
     9001 attttatgcg ttataaaaca aatacagatc gcgtagagca attcttccaa actaagattt
     9061 tcccagatga ctacgttcaa ggggctaata tgatttacga aacagaagca aacttgcctg
     9121 ttgagcatga tatgagtatt ttccctgttg agagtagaga tgattttcca gatggcttga
     9181 cgactattgc accgattcat gtatcgggga ttcgccttgg ttctttgatt atttggcgta
     9241 atgataaaaa attcgaagat gaggacttgg ttcttgttga gattgccagt accgttgttg
     9301 ggattcagct tcttaacttc caacgtgaag aagatgagaa aaatattcgt cgtcgtactg
     9361 ctgtcaccat ggcggtcaat accctttctt actccgaact ccgtgctgtt tcagcaattt
     9421 taggggaatt aaatggaaat gaagggaagt tgactgcgtc agtgattgca gatcgtatcg
     9481 gaatcactcg ctctgtgatt gtcaatgctc ttcgtaaact tgagtctgcg gggattattg
     9541 aaagtcgctc acttggaatg aagggaacct atcttaaggt cttgatttca gatatttttg
     9601 aagaagtgaa gaaaagagat tactaatgac aaaggcttta atttcgattg attatacaga
     9661 agattttgtt gctgatagtg ggaagctgac agcaggtgct ccagctcagg cgatttcgga
     9721 tgccatcagc aaggtaactc gattagcttt tgaacgagga gattatatct tctttactat
     9781 tgatgctcat gaagaaaacg attttttcca tccggaaagt aagttatttc ctcctcataa
     9841 tctgattggg acgagtggac ggaatttata tggagatttg gggatctttt atcaagagca
     9901 tggttcagac agtcgtgtct tttggatgga taaacgccat tactcagctt tttcagggac
     9961 tgacctagat attcgtttga gagagcgtag agtgtctacc gttatcttaa caggtgtctt
    10021 gacggatatc tgtgtcctac atacagctat agatgcctat aatctaggat atgacatcga
    10081 gattgttaaa ccagctgttg cttccatctg gcctgaaaat catcaatttg ccctaggtca
    10141 tttcaaaaat acactcggag ctaagttagt agatgaaaat ctaaatgaac tttctgagta
    10201 acctggttgg tgaaaatgaa aaaatttgaa aaaaagtgtt gacaagcatc ccaaaagttg
    10261 atatactagt aaagtaatcg atgcggggat ggcggaattg gcagacgcgc aggactaagg
    10321 atcctgtgac cgctttaggt cgtgagggtt caagtccctc tctccgcata ggaaaagagt
    10381 tagctaaagc tagctctttt gtatttctct aaaaaattag aatccagtca aatgtagtgg
    10441 agaatcagcg aaaatatggg aaaactgatc cttgtttctg cttttgtcat agaagaataa
    10501 taaagattat cttcttcaaa ttctccgata ttctctaaag ttttgtgcaa gttgcacaga
    10561 acttttttat ttttttggtc atcttgccat agaaatataa agcgttttca tctataatat
    10621 aattatcaaa agacaaaagg agttcacctc atggtagaat tgaatcttaa aaatatttac
    10681 aaaaaatatc caaacagcga acactattca gttgaagatt tcaacttgaa catcaaagat
    10741 aaagaattta tcgttttcgt aggaccttca ggatgtggta aatcaactac actccgtatg
    10801 attgctggtc ttgaagacat tacagaaggt actgcatcta tcgatggcgt ggttgtcaac
    10861 gacgtagctc caaaagaccg tgatatcgcc atggtattcc aaaactacgc tctttaccca
    10921 cacatgactg tttatgacaa catggctttc ggtttgaaat tgcgtaaata cagcaaagaa
    10981 gacattaaca aacgtgttca agaagcagct gaaatacttg gattgaaaga attcttggaa
    11041 cgtaaaccag ctgacctttc aggtggtcaa cgtcaacgtg ttgccatggg gcgtgcgatt
    11101 gtccgtgatg cgaaagtatt cttgatggac gaacctttgt caaacttgga tgccaaactt
    11161 cgtgtatcaa tgcgtgctga aatcgctaaa attcaccgtc gtatcggagc tacaactatc
    11221 tatgtaactc acgaccaaac agaagcgatg acacttgcag accgtatcgt tattatgtca
    11281 gctactaaga accctgctgg tacaggtact atcggacgtg tagaacaaat cggtactcct
    11341 caagaagttt acaaaaatcc agttaacaaa tttgttgcag gattcatcgg aagcccagct
    11401 atgaatttca tcaacgtgaa attggttggt agcgaaattg tttctgacgg tttccgtttg
    11461 aaagtgccag aaggagcatt gaaagttctt cgtgaaaaag gctacgaagg aaaagaattg
    11521 atctttggta tccgtccaga agacgtgaat gcagaacctg ctttccttga aacattccca
    11581 gactgtgttg taaaagcgac tatctctgta tcagaactgc ttggttcaga atctcacctt
    11641 tactgccaag ttggtaaaga cgagtttgtt gcaaaagttg atgctcgtga ctacttgcaa
    11701 acaggtgcaa cagttgagct tggatttgac ttgaacaaag cacacttctt cgatgtagaa
    11761 actgaaaaaa caatctacta aaataaataa aattcaaagc actacaagaa aagatatctc
    11821 tttatcaatt gtagtggaga gatatcagtt aatctaggga gagaaacaaa atgcttctct
    11881 cctttttgct agggaagtca tattatgcat ctatattgtg atgctcttta atactcttcg
    11941 aaaatctctt caaaccacgt caacgtcgcc ttgccgtacg tatgattact gatttcgtca
    12001 gttttatctg caacctcaaa gatgtacttt gagcagctta cggctagttt cctagtttgc
    12061 tctttgattt ccattgagta ttatttgtgg gtaccatcta caagtgaagc tatatgcgta
    12121 aactacgtga gcaattgaat tcgaactaga gaggtaataa taaatttatg ctatagttat
    12181 ggtgacttgt atgcttttga ttctagttta tcaaataata gattagaatt gtcagataat
    12241 atcattttgt gttataatga agaaaaaaca gaggtgttca aatgtcagaa gcaggtcata
    12301 agtttttagc aaaattgggg aaaaaacgct tacgtccagg tggaaagcgt gccacagatt
    12361 ggttaattgc agaaggagga ttttcaaaag aaaagagaat actagaggtt gcgtgtaata
    12421 ggggaactac agcaattgag ttggcacagc gttttggttg taagataact gctgttgata
    12481 tggatgctca agctttagaa gtggctaaaa aatctgctgg aacggcaggt gttgctcatt
    12541 taatcagttt tgaaagagca aatgcaatga aacttcctta tcaagatgct agttttgata
    12601 ttgttataaa tgaagctatg ctgactatgc aagccgatca agctaagaaa aaatgtgtaa
    12661 tggaatatct aagggtatta aaacctggag gtcttctctt gacacatgat gtgcttctta
    12721 aggaagctaa agagtctatc agacaggaat tatcacaagc aattcatgta aatgtaggtc
    12781 ctttaactca agatggttgg gaacaggtga tgatagaatc aggttattgt gatgtgaaag
    12841 cattgactgg tgaaatgaca ttaatgaaat tatcgggtat gatttatgac gaaggtttgc
    12901 taggaacttt gaaaatttgt gtaaatgctt gtaaaaagga gaatagaaag cagtttttaa
    12961 ctatgtataa aatgtttgct aagaataaac agaaattggg ctttattgcg atggctagtt
    13021 ataaatcgtc aaaacgttag ataattattg aagttaactt ttcctttttt ctttcttaaa
    13081 aaatatgcta taatagagag taaaaaactt tgaaagaaag aaaaaagatg aatttaaaag
    13141 attacattgc aacaattgaa aattatccaa aggaaggcat taccttccgt gatattagtc
    13201 ctttgatggc tgatggaaat gcttatagct acgctgttcg tgaaatcgtt cagtatgcta
    13261 ctgacaagaa agtcgacatg atcgtgggac ctgaagctcg tggatttatc gtgggttgtc
    13321 cagttgcctt tgagttggga attggttttg cgcctgttcg taagccaggt aaattgccac
    13381 gcgaagttat ttctgctgac tatgaaaaag agtacggtgt cgataccttg actatgcacg
    13441 cggatgccat taagccaggt caacgtgttc ttattgtaga tgaccttttg gcgacaggtg
    13501 gaactgttaa ggcaactatc gagatgattg aaaaacttgg tggtgttatg gcaggttgtg
    13561 ccttccttgt tgaattggat gaattgaacg gccgtgaaaa aatcggtgac tacgactaca
    13621 aagttcttat gcattattaa tgaaaacagt ccctagggct gttttctcta cactaggata
    13681 taaaaataga ctataactag ttagagaaaa actataattg aaaactatat cttcttgcag
    13741 tataataaaa ggactaagtg tttgagattt gtcttcaaac acatgcaatt attcctgaga
    13801 gagtacagtt aggagagggt tatgccgatt cgaattgata aaaaattgcc agctgttgag
    13861 attttacgga cagagaatat ctttgtcatg gatgatcaac gtgctgcccg ccaagatatc
    13921 cgtcctttga agattttaat tttaaatctc atgccacaga aaatggtcac agagacccag
    13981 ttgttgcgcc acttggctaa tacaccccta caactggata ttgattttct ctatatggag
    14041 agccaccgtt ctaaaacaac tcgttcagag cacatggaga ccttctataa aacttttcct
    14101 gaagtcaagg atgagtattt tgatgggatg atcatcacgg gtgctccagt tgagcattta
    14161 ccatttgagg aagtggacta ttgggaggaa tttagacaga tgcttgagtg gtctaagact
    14221 catgtctatt cgacccttca tatctgttgg ggagctcagg ctgggcttta tctgcgctat
    14281 ggtgtagaaa aataccagat ggacagtaag ctatcaggta tttatcctca ggacacccta
    14341 aaagagggtc accttctatt tagaggcttt gatgatagct atgtatcccc tcattcacgg
    14401 cacacggaga tttctaagga agaggtctta aacaagacta atctcgagat tttatcagaa
    14461 ggacctcagg ttggggtttc tattttggcc agtcgtgatt tacgagaaat ttatagtttt
    14521 ggtcatttgg agtatgaccg tgataccttg gcaaaagagt attttcgaga tcgtgatgca
    14581 ggtttcgacc cacatattcc agaaaattac tttaaagatg atgatgttaa tcaggtacct
    14641 tgtctttgtt ggtcttcatc tgcagccctc tttttcagta attgggtaaa ccatgcggtc
    14701 tatcaggaga cgccttttga ctggagaaag atagaagatg atgcatctgc atatgggtat
    14761 ttataagagg aattatgaca tatttagacg cttttaaatc aggtaccttg gttttaccga
    14821 gtgccctgct cttgcatttt aaggaactct ttccttctag cgacgatttt ctggtttggc
    14881 aatttttcta tttgcaaaat acgacaggct tagaagaaat gtcgccaagc cagattgctg
    14941 aaaggattgg caaggaaatt tcggatgtca accagtccat ttctaatctg acggaaaggg
    15001 gactgctcca gtatcgtact atcgaattaa atggcgaaat tgaattgctc tttgatgcta
    15061 gtttggcctt ggaacgtttg gatgacctgt ttggagcagt tcattcaagt tcagaccagc
    15121 taacaccaca aaaccagctc aaggatttgg tggaaacctt ccagcaggag ttgggacgat
    15181 tgttgacgcc ttttgagatt gaggatttga ccaagacact aaaggaagat ggaaccagtg
    15241 ctgacttgat taaggaggct cttcgtgaag ctgttttgaa tggaaaacca aactggaagt
    15301 acattcaggc gattttgaga aactggcgcc atgaaggaat caagagtgtg gctcaaattg
    15361 aggccaagag agcagaaaga gaagcaagca atcctcagtt gacacaggta tctgcagatt
    15421 tcagaaatgc catggatctc tggaaggatt aatccatgca agtaggcttg aaatccgagt
    15481 aagatttgca agctgtgtat aattgtgata gaataaatag aaaataaatt gaaaaaagag
    15541 gtatgtgaaa tgtcacgtaa accatttatc gctggtaact ggaaaatgaa caaaaatcca
    15601 gaagaagcta aagcattcgt tgaagcagtt gcatcaaaac ttccttcatc agatcttgtt
    15661 gaagcaggta tcgctgctcc agctcttgat ttgacaactg ttcttgctgt tgcaaaaggc
    15721 tcaaacctta aagttgctgc tcaaaactgc tactttgaaa atgcaggtgc tttcactggt
    15781 gaaactagcc cacaagtttt gaaagaaatc ggtactgact acgttgttat cggtcactca
    15841 gaacgccgtg actacttcca tgaaactgac gaagatatca acaaaaaagc aaaagcaatc
    15901 tttgcgaacg gtatgcttcc aatcatctgt tgtggtgaat cacttgaaac ttacgaagct
    15961 ggtaaagctg ctgaattcgt aggtgctcaa gtatctgctg cattggctgg attgactgct
    16021 gaacaagttg ctgcctcagt tatcgcttat gagccaatct gggctatcgg tactggtaaa
    16081 tcagcttcac aagacgatgc acaaaaaatg tgtaaagttg ttcgtgacgt tgtagctgct
    16141 gactttggtc aagaagtcgc agacaaagtt cgtgttcaat acggtggttc tgttaaacct
    16201 gaaaatgttg cttcatacat ggcttgccca gacgttgacg gtgcccttgt aggtggtgcg
    16261 tcacttgaag ctgaaagctt cttagctttg cttgactttg taaaataatc agtaagtagc
    16321 aaaagctagg tggaacagca ttcagatgtc tgttacattt tttataggag agcaaagatt
    16381 gaaaacaaaa attggattag caagtatctg tttactaggc ttggcaacta gtcatgtcgc
    16441 tgcaaatgaa actgaagtag caaaaacttc gcaggataca acgacagctt caagtagttc
    16501 agagcaaaat cagtcttcta ataaaacgca aacgagcgca gaagtacaga ctaatgctgc
    16561 tgcccactgg gatggggatt attatgtaaa ggatgatggt tctaaagctc aaagtgaatg
    16621 gatttttgac aactactata aggcttggtt ttatattaat tcagatggtc gttactcgca
    16681 gaatgaatgg catggaaatt actacctgaa atcaggtgga tatatggccc aaaacgagtg
    16741 gatctatgac agtaattaca agagttggtt ttatctcaag tcagatgggg cttatgctca
    16801 tcaagaatgg caattgattg gaaataagtg gtactacttc aagaagtggg gttacatggc
    16861 taaaagccaa tggcaaggaa gttatttctt gaatggtcaa ggagctatga tgcaaaatga
    16921 atggctctat gatccagcct attctgctta tttttatcta aaatccgatg gaacttatgc
    16981 taaccaagag tggcaaaaag tgggcggcaa atggtactat ttcaagaagt ggggctatat
    17041 ggctcggaat gagtggcaag gcaactacta tttgactgga agtggtgcta tggcgactga
    17101 cgaagtgatt atggatggtg ctcgctatat ctttgcggcc tctggtgagc tcaaagaaaa
    17161 gaaagatttg aatgtcggct gggttcacag agatggtaaa cgctatttct ttaataatag
    17221 agaagaacaa gtgggaaccg aacatgctaa gaaaatcatt gatattagtg agcacaatgg
    17281 tcgtatcaat gattggaaaa aggttattga tgagaacgag gtggatggtg tcattgttcg
    17341 tctaggttat agcggtaaag aagacaagga attggcgcat aacattaagg agttaaaccg
    17401 tctgggaatt ccttatggtg tctatctcta tacctatgct gaaaatgaga ccgatgctga
    17461 gaatgacgct aaacagacca ttgaacttat aaagaaatac aatatgaacc tgtcttaccc
    17521 tatctattat gatgttgaga actgggaata tgtaaataag agcaagagag ctccaagtga
    17581 tacagacact tgggttaaaa tcatcaacaa gtacatggac acgatgaagc aggcgggtta
    17641 tcaaaatgtg tatgtctata gctatcgtag tttattacag acgcgtttaa aacacccaga
    17701 tattttaaaa catgtaaact gggtagcggc ttatacgaat gctttagaat gggaaaaccc
    17761 ttattattca ggagaaaaag gttggcaata tacctcttct gaatacatga aaggaatcca
    17821 agggcgcgta gatgtcagcg tttggtatta agcgatgatt tgaaagaggg atgtgatagt
    17881 agcaccctct ttttctttgt tttatgatag ttcatcctcg agtaaattca agatcttgct
    17941 cggaaatgaa gcttatatag tagattgaat atagacaaat accttgtgat tggtaaaaca
    18001 ttttagaaat tcatttacct ttcctaatcg acttggtttc atcttatttc aatctattat
    18061 agtattgggg aatttcttca aaccacatca gcttggtcag ttctacctgc gacctcaaaa
    18121 cttgtgcttt ggtcaagctg ggtttagttt cctagtttgc tgatggattt ccattgacta
    18181 taagcatcca accctctttt tgtcttctaa agaattctta aattatcagt ctattgcaac
    18241 ttttctcatg tgggtcattt ggcttgcaat tgtctttcct tagtagtata ctgaggcagt
    18301 aatcattaag aagtggttac ataaaaataa tgaatgaggt aaaataaaat ggtagaattg
    18361 aaaaaagaag cagcaaaaga tgtcgcaaca ttaacaaaag cagcgccagt agcattggca
    18421 aaaacaaagg aagttttgaa tcaagcagtt gctgatttgt atgtagctca cgttgctttg
    18481 caccaagtgc actggtatat gcatggtcgt ggtttccttg tatggcatcc aaaaatggat
    18541 gagtacatgg aagctcttga tggtcattta gatgaaatca gcgaacgctt gatcacactt
    18601 ggtggaagcc cattctctac tttgacagag ttccttcaaa acagtgaaat cgaagaagaa
    18661 gctggtgaat accgtaatgt tgaagaaagc ttggaacgtg ttctagctat ttatcgctac
    18721 ctcatcactc ttttccaaaa agcgttggat gtgactgacg aagaaggcga tgatgttaca
    18781 aacgatattt ttgttggtgc taaggctgaa cttgagaaaa cagtttggat gcttgccgca
    18841 gaacttggac aagcacctgg tttgtaagaa acaagacaac atagataaat ctgtaggaaa
    18901 tttcttacag attttttcta ttttgtaagc tattccaaac cagtcttttt ttgagttttt
    18961 tgataaaata gtactatcag tgaaaaggat ggaagcatga ctaagaaaat cgtagctatt
    19021 tgggcccagg atgaagaggg tgtgattggt aaggacaatc gtctgccttg gcatttgcca
    19081 gcagaattgc agcactttaa agaaacaact ctgaatcatg ctatcttgat ggggcgggta
    19141 acctttgatg gaatggggcg tcgcttgctt ccaaaacggg agaccctgat tttgacgcgt
    19201 aatccggaag aaaagataga tggggttgct acttttcagg acgtccagtc tgttcttgac
    19261 tggtatcagg ctcaagaaaa gaatctctac attatcggtg ggaagcaaat ttttcaggct
    19321 tttgaagctt accttgatga agtgattgtc actcacattc atgctcgggt ggaaggagat
    19381 acctatttcc ctgaagagct tgacttgtct ctttttgaga cagtttcaag caaattttac
    19441 gccaaagatg agaagaatcc ttatgatttt accatccaat accgcaagag aaaggaagtt
    19501 taatggaacg gagtttattt ggtctattca cggcttttct gtgtttcatc tgctttctgg
    19561 caggagcaca agcttttcgt aaaaagcgtt acgggctttc tatcctcctt tggttaaatg
    19621 cctttaccaa tctggtcaat agtattcatg ctttttacat gaccttattt tagatagaat
    19681 gacagtatag aatggaagga aatcatgtct acaaatagaa aaaatgatat gatggtttat
    19741 tgctcatttt gtggcaaaaa ccaagaagaa gtacaaaaaa taattgctgg caacaatgct
    19801 tttatttgta atgaatgcgt ggagttagct caggaaatca ttcgagaaga attggttgag
    19861 gaagtcttgg cagacttgtc tgaggtgcca aaaccaattg aactcctcca tatcttgaac
    19921 cactatgtaa ttggtcaaga tcgtgccaag cgtgccttgg cagtggcggt ttataaccac
    19981 tacaaacgca tcaatttcca cgatacacgc gaagagtcag aagatgtgga tttgcagaag
    20041 tcaaacattt tgatgattgg cccaactggt tcagggaaaa ctttccttgc ccagaccttg
    20101 gctaagagct tgaatgtacc ttttgctatt gcggatgcga cagctctgac ggaggctggt
    20161 tatgtgggtg aggatgtgga aaatatactc ctcaaactct tgcaggttgc tgactttaac
    20221 atcgaacgtg cagagcgtgg cattatctat gtggatgaaa ttgacaagat tgccaagaag
    20281 agtgagaatg tgtctatcac acgtgatgtt tctggtgaag gggtgcaaca agcccttctc
    20341 aagattatcg agggaactgt tgctagcgta ccgcctcaag gtggacgcaa acatccacaa
    20401 caagagatga ttcaagtgga tacaaaaaat atcctcttca tcgtgggtgg tgcttttgat
    20461 ggtattgaag aaattgtcaa acaacgtctg ggtgaaaaag tcatcggatt tggtcaaaac
    20521 aataaggcga ttgacgaaaa cagctcatac atgcaagaaa tcatcgctga agacattcaa
    20581 aaatttggta ttatccctga gttgattgga cgcttgcctg tttttgcggc tcttgagcaa
    20641 ttgaccgttg atgacttggt tcgcatcttg aaagagccaa gaaatgcctt ggtgaaacaa
    20701 taccaaacct tgctttctta tgatgatgtt gagttggaat ttgacgacga agcccttcaa
    20761 gagattgcta ataaagcaat cgaacggaag acaggggcgc gtggacttcg ctccatcatc
    20821 gaagaaacca tgctagatgt tatgtttgag gtgccgagtc aggaaaatgt gaaattggtt
    20881 cgcatcacta aagaaactgt cgatggaacg gataaaccga tcctagaaac agcctagagg
    20941 tgactatgga acttaataca cacaatgctg aaatcttgct cagtgcagct aataagtccc
    21001 actatccgca ggatgaactg ccagagattg ccctagcagg gcgttcaaat gttggtaaat
    21061 ccagctttat caacactatg ttgaaccgta agaatctcgc ccgtacatca ggaaaacctg
    21121 gtaaaaccca gctcctgaac ttttttaaca ttgatgacaa gatgcgcttt gtggatgtgc
    21181 ctggttatgg ctatgctcgt gtttctaaaa aggaacgtga aaagtggggg tgcatgattg
    21241 aggagtactt aacgactcgg gaaaatctcc gtgcggttgt cagtctagtt gaccttcgtc
    21301 atgccccgtc agcagatgat gtgcagatgt acgaatttct caagtattat gagattccag
    21361 tcatcattgt ggcgaccaag gcggacaaga ttcctcgtgg taaatggaac aagcatgaat
    21421 cagcaatcaa aaagaaatta aactttgacc cgagtgacga tttcatcctc ttttcatctg
    21481 tcagtaaggc agggatggat gaggcttggg atgcaatctt agaaaaattg tgaggaaaag
    21541 aaaatggcaa aaacaattca tacagataag gccccaaagg ctatcggacc ctatgttcaa
    21601 ggaaaaatcg ttggcaacct tttgtttgct agcggtcaag ttcccctatc ccctgaaact
    21661 ggggaaattg taggagagaa tatccaagaa cagacagagc aagtcttgaa aaacatcggt
    21721 gctattttgg cagaagcagg aacagacttt gaccatgttg tcaaaacaac ttgcttcttg
    21781 agcgatatga acgactttgt tccttttaat gaggtttacc aaacggcctt caaagaggaa
    21841 ttcccagctc gttcagctgt ggaggtagct cgtcttcctc gtgatgtaaa agtcgaaatt
    21901 gaagtcatcg cagagattgg ataagctagt tgaagtttgg tgttgccaaa cttcttttga
    21961 tataaggaga aaaagatgac aaagaaacaa cttcacttgg tgattgtgac agggatgagt
    22021 ggcgcaggga aaactgtagc cattcagtcc ttcgaggatc taggttattt caccattgat
    22081 aatatgccgc cagctctctt gcctaagttt ttgcagctgg ttgaaattaa ggaagacaat
    22141 cctaagttgg ccttggtagt ggatatgcgt agccgttctt tcttttcaga gattcaagct
    22201 gttttggatg agttggaaaa tcaagatggt ttggatttca aaatcctctt tttggatgcg
    22261 gctgataagg aattggtcgc tcgttacaag gaaaccagac ggagtcaccc actagcagca
    22321 gacggtcgta ttttagatgg aatcaagttg gaacgtgaac tcttggcacc tttgaaaaat
    22381 atgagccaaa atgtggtgga tacgactgaa ctcactccac gtgagctgcg taaaaccctt
    22441 gcagagcagt tttcagacca agaacaagcc cagtctttcc gtatcgaagt catgtctttc
    22501 ggatttaagt atggaatccc gattgatgcg gacttggtct ttgatgtccg tttcttgcca
    22561 aatccctatt atctaccaga actgagaaac caaacgggtg tggatgaacc tgtttatgat
    22621 tatgtcatga accatcctga gtcagaagac ttttatcaac atttattggc cttgattgag
    22681 ccgattctgc caagttacca aaaggaaggt aagtccgttt tgaccattgc tatgggatgt
    22741 acgggtggac aacaccgtag tgtggcattt gctaaacgct tggtgcagga cttatccaag
    22801 aattggtctg ttaatgaagg gcatcgcgac aaagaccgca gaaaggaaac ggtaaaccgt
    22861 tcatgagaaa accaaagata acggtgattg gtggagggac tggaattccc gtcattctaa
    22921 aaagtctgcg ggaaaaagat gtggaaatcg cagctatcgt gacggtggca gatgatggtg
    22981 gttcttcagg tgaactccga aaaaatatgc aacagttgac accgccaggt gatcttcgta
    23041 atgtccttgt ggccatgtcg gatatgccta agttttatga gaaggtcttt cagtatcggt
    23101 tctctgagga tgccggagcc tttgctggcc atccattggg aaatctcatc attgctggct
    23161 tgtcagaaat gcagggttca acctataatg ccatgcagtt attgagcaaa tttttccata
    23221 caacagggaa aatttatcct tccagtgacc atcctttgac ccttcatgca gtctttcagg
    23281 atgggacaga agtggctgga gagagtcata ttgtagacca tcgaggcata attgacaatg
    23341 tctatgtgac caatgcccta aacgatgata cgcctctggc cagccgtcga gtagtgcaga
    23401 ccatccttga aagtgacatg attgtcctag ggccaggttc cctctttacc tctattttgc
    23461 ccaatatcgt gattaaggaa attgggcggg ctcttttgga aactaaggca gaaattgcct
    23521 atgtctgcaa tatcatgacc caacgtgggg agacggaaca ctttacagat agcgaccacg
    23581 tggaagtctt gcatcgtcac cttggtcgcc cttttatcga cactgtcttg gtgaatattg
    23641 aaaaagtgcc tcaggaatac atgaattcca accgttttga tgaatactta gtgcaagtgg
    23701 aacacgattt tgtaggtctt tgtaagcaag tttcgcgcgt gatttcatct aacttccttc
    23761 gtctggaaaa tggcggtgcc ttccacgatg gagatttgat tgtggacgag ttgatgcgca
    23821 ttatacaggt gaaaaaatga gtttcacagt agcagtaaaa gaagaaatcc tgggccaaca
    23881 ccatctgagc tggcatgaat tatctgccat tatcaaaatg tctggtagca tcggtctctc
    23941 gacttcgggc ttgactttgt cagttgtgac agaaaatgcc aaactggccc gtcacctcta
    24001 tgagtccttt cttcatttct atgaaatcaa atctgaaatt cgtcaccacc aacgtagcaa
    24061 tcttcgcaag aatcgcgtct ataccgtttt tacagatgaa aaggtgcagg atttgttaag
    24121 tgatttgcac ttggcagact ctttctttgg cctggaaaca ggtattgatg aggcgatttt
    24181 atcggatgag gaagcaggtc gtgcctatct ctgtggcgct ttcttggcaa atgggagcat
    24241 tcgtgaccct gagtcaggca agtaccagtt ggaaatcagt tctgtttatc tggaccacgc
    24301 gcaaggaatt gcctcccttc tccaacagtt tttactggat gccaaggtgc ttgagcgcaa
    24361 gaagggggct gtgacctatc tccagagagc agaagacatt atggacttct tgatagtaat
    24421 cggagccatg caggcacgtg atgattttga gcgggttaag attttgcgag aaacccgtaa
    24481 cgacctcaat cgggctaata atgccgagac agctaatatc gctcggacag tttctgccag
    24541 catgaagacc attaacaata tcagtaaaat caaagatatc atgggcttag aaaatttgcc
    24601 agtagatttg caggaagtgg cgcaactgag gattcagcac ccagactact ctatccagca
    24661 gttagcagat agtctcagca cccctctgac caaaagtggt gtcaatcaca gactcagaaa
    24721 aatcaataag atagccgatg aattataaaa ccacgaatcc tatgtgactc gtggttcttt
    24781 tttataaact agtagagtgt tttggttgta ctttttgttc agggtcaatg tagttgatag
    24841 cgttgttgac agcagttgga gcttctccga ggcctgtcgc aatcagatca atttttccgt
    24901 catagtagca gcagtcaccg atagcataga tacctgcttg gctggattcc tgtttgctgt
    24961 tgacgataat cttgtgacgg ttgaggtcga gcccccagtt tttaaggtta ccgacagaag
    25021 atttgaaacc atagttgaca aagaggtggt ctaggtcaat ggtttcagtt tcatcagatt
    25081 tgacttttgt gatttcaagt ttatcaagtg tttttccatt tccaaggagt tggctagggg
    25141 cgaatggtgt cttgatggtt acagatgatt cttgcaaggc ttgaacactg tgttccaagg
    25201 cacggaaatt atctctgcgg tgaacaaggg tagttggtgc gattttttca aaagccaaag
    25261 cccaatccac agccgagtct cccccaccaa gaatcgtcac tttcttacca gcgtattgct
    25321 gaatgttaga aacgtggtag tggatatttt catagccctc aacaccttca agttccagcg
    25381 gacgtggttt gaaggcaccg ccacccatag cgatgatgac tgttttagtc aggtgacttc
    25441 ctttagaagt tgtgatggca aattcttctt cttgtttgtc aatctcaaga accgtttcat
    25501 tgagatgaat aggggtatca aatccattta gctgttcaat caagcggtta gtcaactctt
    25561 ctccagtcag gtttgggaag cctggtacgt ctaggatttc cttttcaggg tagagaatag
    25621 caggttgtcc acctagctgg ggaagagagt cgatgatttg aaccttggct tggcgtaggt
    25681 gggcataaaa ggctgcaaaa agcccgacag gaccaccacc cacaatggta atatcataga
    25741 gttgagacat agtttctcct ttgttttttc tagtcagttt attttatcat atttttgttc
    25801 aatgtaaaat ggactaggat agggaaaaaa atgccagaaa atggtataat aggacgaaag
    25861 tgttttgata gggaggatat cagggatgaa ttttcaacaa ttatccaatc tgcaatattg
    25921 gaccagtttg tttgcaagtc catggacgat agctatcaat ctgattgata ttttgattgt
    25981 tgcttatatt ttataccatt ttacaaaagc tattgcagga accaagatta tgattttggt
    26041 acgtggagtt ttggtgttta ttttagctca aatccttgca aatatgattg gtttgactac
    26101 gatttcttgg ttaatcaatc aaattattac ttatggggtt attgcggcgg ttgttatctt
    26161 ctctccagag attcggactg gtttggaacg tttgggaaga gcgacagatt tcttttccaa
    26221 tgcccctatt agtgctgagg aacagatgat tcgtgccttt gttaagtctg ttgaatacat
    26281 gagtcctcgt aaaatcgggg ccttggttgc tattcagcgt gtacgtacct tgcaggagta
    26341 tatttcgaca ggaattccct tggatgctaa gatttctgca gaacttctca ttaacatttt
    26401 tattcccaac actcccctac atgatggtgc ggtgattatc aaagaagaac gtatcgctgt
    26461 gacgtctgcc tatctgccct tgacaaaaaa cacagggatt tccaaggaat ttgggaccag
    26521 acaccgggcg gctatcggtt tatcagaagt ctcagatgcc ttgacttttg tcgtatcaga
    26581 ggaaacggga ggaatttcga taacctataa tggaaggttt aagcacaacc taacacttga
    26641 tgaatttgaa acagaattac gtgaaatctt acttccaaaa gaggaagtgg gtcttagttt
    26701 taaagaacga ttgctaggag gatggaaaca tgaaaaaaaa tagtttatat atcatatcct
    26761 cactcttttt tgcttgtgtc ttatttgtct atgctacggc gacgaatttt caaaacagta
    26821 ccagtgctag gcaggtaaaa acggaaacct atactaatac agtaacaaat gtccctattg
    26881 acatacgcta taatagtgat aagtatttta ttagcggttt tgcttcagaa gtatcagtgg
    26941 tcttgactgg tgcaaatcgc ctatcgctag ctagtgaaat gcaagaaagt acacgtaaat
    27001 tcaaggttac tgctgaccta acagatgccg gtgttggaac gattgaagtt cctttgagca
    27061 ttgaagattt acccaatggg ctgaccgctg tggcgactcc gcaaaaaatt acagtcaaga
    27121 ttggtaagaa ggctcagaag gataaggtaa agattgtacc agagattgac cctagtcaaa
    27181 ttgatagtcg ggtacaaatt gaaaatgtca tggtgtcaga taaagaagtg tcgattacga
    27241 gtgaccaaga gacattggat agaattgata agattatcgc tgttttgcca actagcgaac
    27301 gtataacagg taattacagt ggttcagtac ctttgcaggc aatcgaccgc aatggtgttg
    27361 tcttaccggc agttatcact ccgtttgata caataatgaa ggtgactaca aaaccagtag
    27421 caccaagttc aagcacatca aattcaagta caagcagttc atcggagaca tcttcgtcaa
    27481 cgaaagcaac tagttcaaaa acgaattaaa aatagaaaag gattttataa caatgggtaa
    27541 atattttggg actgatggag tccgtggaga agctaaccta gaactaacac cagaattagc
    27601 ctttaaacta ggacgttttg gaggctatgt tcttagtcaa catgaaacgg aagcgccgaa
    27661 agtctttgta ggacgtgaca cacgtatttc aggggaaatg ttggaatcgg ccttggtggc
    27721 aggtctcctt tcagtaggga ttcacgtata caaacttggt gtccttgcaa caccagcagt
    27781 agcttacttg gttgaaactg aaggagcaag tgccggtgtc atgatttctg ctagccacaa
    27841 cccagccctt gataacggaa tcaagttctt tggcggtgat ggcttcaaac tagatgatga
    27901 aaaagaagca gaaattgaag ccttgctaga tgctgaggaa gacactcttc ctcgtccaag
    27961 tgcagaaggc ttaggaattt tggtagatta tccagaaggc ttgcgtaagt atgaaggata
    28021 ccttgtttca actggaactc ctcttgatgg aatgaaggtt gccttggata cagctaatgg
    28081 agcagcttct accagtgccc gtcaaatctt tgcagacctt ggtgcccaat tgacggttat
    28141 cggggaaaca ccagacggtc ttaacatcaa ccttaatgtt ggttcaacac atccagaagc
    28201 ccttcaagaa gtggtcaaag aaagtgggtc agctattggt ttggcctttg atggagacag
    28261 tgaccgcttg attgctgttg atgagaatgg tgacatcgtt gatggtgaca agattatgta
    28321 catcatcgga aaataccttt ctgaaaaagg acaattggct caaaatacaa ttgtgacaac
    28381 tgttatgtct aaccttggtt tccacaaggc cttgaatcgc gaaggtatta acaaggcagt
    28441 tactgcagtt ggtgaccgct acgttgttga agaaatgaga aaatcaggct acaaccttgg
    28501 tggtgaacag tctggtcacg ttatcttgat ggattacaat accacaggtg atggtcaatt
    28561 atcagcagtt caattgacta aaatcatgaa ggaaactggt aagagcttat cagagttggc
    28621 ggcagaagta acgatttatc cacaaaaatt agttaatatc cgagtggaaa acgtcatgaa
    28681 ggaaaaggcc atggaagtgc cagctatcaa ggccatcatc gagaagatgg aagaagaaat
    28741 ggcggggaac ggccgtatcc ttgttcgtcc aagtggaaca gaacccctct tgcgtgttat
    28801 ggcagaagcg cctacaacag aagaagtaaa ctactatgtt gataccatca cagatgtagt
    28861 tcgtgctgaa attgggattg actaaatcct agaaaactag atgaaaataa aaaattatgg
    28921 tacaatagct tataatattg tagccgatgg agaaagacat gaatcttaaa cgtgaacaag
    28981 aatttgttag tcagtatcat tttgatgcgc gtaattttga atgggaaaat gaaaatggag
    29041 ctcctgaaac caaggtggat gtgaatttcc aattgctcca acatgaccaa gaaaatcaag
    29101 tgacttcctt gattgtcatc ttgagcttta tgattgtatt tgataagttt gtcattagtg
    29161 gaacaatctc acaagtaaac catatcgatg gccgtattgt caatgaacca agtgaattga
    29221 accaagaaga ggtggaaacc ttggctcgtc catgtttgaa catgctcaat cgtttgactt
    29281 acgaagtgac tgaaattgca ttagacttac caggaattaa tttggagttc taatatgaaa
    29341 ttagctgttt tcacagattc ctctgcttat ctcagtgcag agatcttgca aagagaagac
    29401 ttgtttgtct tggatattcc tgtcaatatt gatggtgagg aatatgtcga aggcatcaat
    29461 ctgtctgctg aggaatttta ccaaaaaatg gctcaggctt ctgaattgcc taagaccagt
    29521 caaccaagta ttgccaagtt agatgaaatc ttaacttcgc tcaaagaaca aggctataca
    29581 catgccttgg ggcttttcct atcttctgga atttcaggtt tttaccaaaa tatccagtat
    29641 atggtcgatg actatgaggg cttaaccatt gctttcccag acactttgat tacaagtgct
    29701 cccctaggca tcatggttga aagcgtcttt aattggcgtg atcagggcga tgattttgcc
    29761 agcattcagg ataagctagc cattcaaatc agccgtacgt cagcctttat catggtagat
    29821 gacttggatc atttggtaaa aggtggacgc ctttcaaatg gggctgccat tttgggcaat
    29881 ttgcttagca ttaagccaat cctttatttt aacgatcaag gtgtgattga agtttacgaa
    29941 aaagttcgta ctgaaaagaa ggccaccaaa cgcttaattg aaattatcaa ggaaacaacg
    30001 gcttcaggtc aataccgggt cattgtcatt catgggaatg ctcctgaaaa ggctgaagaa
    30061 ttgcgtcagc atttgcttga ttttggcttg ggttcggatg tttcacttgc tacatttggt
    30121 agtgtcattg gaacgcacct aggagcagga agtattgctc taggttatat tccagtgatt
    30181 tagttggcac ttctaggcta gttaatctta gaaattgaac acggactacc tgcctcttga
    30241 aaaaagatgc ctgtcttgcc tttcgtggaa agtcagtgcc attccctatt tttcaggggc
    30301 agctaaggtc ctttgtatct tgataattga acacgcctgg aaccctgtgt gaaaaagata
    30361 gttcttccaa gaagtagaca cttcttgatc agaattccta ttttcacttt gtgttcttac
    30421 aggctttgta ttttggacag gagtagagat gagtattcga gtaattattg ccggttttaa
    30481 gggaaagatg ggccaggctg cttgtcagat ggtattgact gatccagact tggacttggt
    30541 agcagttttg gatccttttg agtctgagtc agaatggcag ggtattcctg ttttcaagga
    30601 taaggctgat ttagctggtt ttgaagcgga tgtctggata gattttacta ctccagctgt
    30661 tgcctacgaa aatacacgtt ttgctcttga aaatggcttt gctccagtag ttggaacgac
    30721 tggtttcacg agtgaagaaa ttgcagagct aaaagaattt tctcgtgccc aagacttggg
    30781 tggcctgatt gcccctaact ttgccttggg tgctgtctta ctcatgcaat ttgcgacgca
    30841 ggctgccaaa tatttcccaa atgtggagat tattgagctc catcatgaca agaaaaagga
    30901 tgctccgagt ggaacagcca ttaaaacagc tgagttgatg gcagaggttc gagagtcaat
    30961 tcagcaaggt gcagcagatg aggaagagct gattgctggt gctcgtggtg ctgactttga
    31021 tggtatgcgc atccactcag ttcgtttgcc aggcttggta gctcatcagg aagtcatctt
    31081 tggcaatcag ggagaagggt tgaccctccg tcatgactcc tatgatcgca tctccttcat
    31141 gacaggagtc aatttgggaa ttaaagaagt tgtcaagcgt catgagcttg tctatggatt
    31201 agaacactta ttatgagatt aacgcaaatg ccttctgaat ttcagaaggc tttaccagta
    31261 ttagaaaaaa ttaaagaagc aggctttgag gcttattttg ttgggggctc tgttcgagat
    31321 gcccttctcc atagccctat ccacgatgtg gatattgcga cgtcttctta tccagaagag
    31381 accaagcaga tttttccgcg aacagccgat atcggaatcg agcatggaac cgtcttggtc
    31441 ttagatgggg atgaggagta tgaggtaaca acctttcgga cagaggatgt ctatgtggac
    31501 tatcgcagac ccagtgcggt ttcctttgtg cgctcgctag aagaagacct caaacgccgt
    31561 gatttcacag tcaacgcctt tgccttggat gagacaggag aaatcgttga cttgttccat
    31621 ggtttagaag atttggaaaa gcaagtcttg cgagcagttg gagtggctag tgagcgtttc
    31681 aacgaagatg ctttacggat tatgcgtggt ttccgttttc aggctagtct tggttttgca
    31741 cttgagccag aaacatttaa agctatgaag accttgacgc cgcttttgga gaaaatttct
    31801 gtagagcgta ccttcgtcga atttgataaa ctcttgctgg ctccattttg gagaaggggc
    31861 ttggcttcca tgattgagag tcaagcttat gactatctcc ctgatatggc atctagccag
    31921 gacaagctca acagactgtt tgatttggag actgatttta cttttgaatc ctctgaacaa
    31981 gcctgggcgg ctttactatg ggctttggag attgaaaatg cgcagtcatt tttgaaatct
    32041 tggaagacct cacgccagtt tgccaagcaa gttcaggatt tgctgattat tttggctctg
    32101 cgtgaaaatg gagaattgag caagcgagat tgttatcgct ttgacataga tttgctttta
    32161 caggctgaaa atcttcgtca agctcaagga aaagaagtca acccacaagc catcacagaa
    32221 aaataccaaa gcttgactat ccatgacaag aaagagattc agattaatgg cgatattttg
    32281 atcaaggaat atggctatca gccaggccca gacttgggag agattttaac agagattgag
    32341 tttgccattg tcgatggaga attggagaat aatcgtgaag ccatccatgc ttacctgagg
    32401 gagaaaaaat gagtgatttt atcgttgaaa aactaagtaa atccgttggt gacaagaccg
    32461 tttttaggga tatttccttt attatccatg acttagacag aattggttta atcggtgtca
    32521 atgggactgg caagaccacc cttttggacg tcctttctgg tgtttctgga tttgatgggg
    32581 atgtcagtcc tttttcagct aaaagtgatt accagattgg ttatttgact caggatcctg
    32641 attttgatga tagaaagaca gttttggata cggttctatc tagtgaactc aaggaaatcc
    32701 agctcattcg tgagtatgaa ttgattatgc tcgactatag tgaggacaag caggcgcgtt
    32761 tggaacgtgt catggcagag atggactctc tccaagcttg ggaaatcgag agtcaggtca
    32821 agaccgttct taacaaattg ggcattcaag acttatctac tcctgttggg gaattgtcag
    32881 gtggtctgag aagacgggta cagttggcac aagtcttact tggcaaccac gaccttttgc
    32941 ttttggatga gccgaccaac catctggata ttgcgattat tgagtggctg accctctttt
    33001 tgaaaaattc taagaagacc gtccttttta tcactcacga tcgttatttc ttagacgctt
    33061 tgtcaacacg gattttcgag ttggagcgag caggcttgac agaatatcag ggcaattacc
    33121 aggactatgt tcgccttaag gcagaacagg acgagcgcga tgcagctcta cttcataaaa
    33181 aagaacaact ctacaaacaa gaactggcct ggatgagcag acaaccgcag gcgcgtgcga
    33241 ccaagcaaca agctcgtatc aatcgtttcc atgatctgaa aaaggaagtt tcaggcagta
    33301 gtgctgagac agacttgact atgaactttg aaaccagtcg gattgggaag aaagtcatcg
    33361 agtttcagga tgtttccttt gcctatgaaa ataagcccat tttgcaagat tttaatctct
    33421 tagttcaggc taaagaccgt attggaattg ttggggacaa tggtgttgga aaatcaaccc
    33481 tacttaacct gattgcagga agtcttgagc cgacagcagg acaagttgtg attggggaaa
    33541 ctgttcgcat cgcctatttc tctcaacaaa ttgagggttt ggatgaaagc aagcgtgtga
    33601 tcaattacct gcaggaagtg gcagaggagg tcaagaccag tggtggttct acgacttcca
    33661 tcgctgagtt gctggagcaa ttcctcttcc cacgttcgac gcatgggacc ttgattgaga
    33721 agttgtcagg gggtgagaaa aaacgtcttt atctcctcaa actgcttttg gaaaaaccaa
    33781 atgttcttct tttagacgag ccaaccaatg acctagatat tgcaactttg acagtcttag
    33841 agaatttctt gcaaggtttt gcaggtcccg ttttaacagt cagtcacgac cgctatttct
    33901 tggataaggt agcgaccaag attctcgctt ttgaggatgg caagattcgt cctttctttg
    33961 gtcattacac cgactatctt gatgaaaaag cttttgaaac agatatggcc aatcaagtgc
    34021 aaaaggccga aaaggaaaaa gtggtcaagg ttcgagaaga caagaaacgc atgacctacc
    34081 aagaaaagca ggagtgggca agtattgaag gtgatattga aaccttggaa aaacgtatcg
    34141 ctgctattga agaggaaatg caggctaacg gctctgactt tggtaagctg gctactctcc
    34201 aaaaagaatt ggatgagaaa aatgaagcac tccttgaaaa atacgaacgc tatgagtatc
    34261 tcagtgaatt tgatagttaa gactattcga aaatcaaagt gcaaactatg tcggcttcac
    34321 attgccgact caagtacagc ctgcgaccgg cttcctaatt tgcactttga tttttattga
    34381 gtataaacga atagaaaaat ctcgtctcat gaaaggattt ctctattctt ttttggtttc
    34441 ttgatgaaag atattttgcc aggtttcgtg gcgacgccag atactggtat ggatgatacc
    34501 atctaactca tagcagatga gtttggtttt ttgactgatg gaagtaattt gaatgtcctt
    34561 gatagcagaa tttaactctt ttttggtctt ataagcctct ttatccatct gctctccatc
    34621 ttggcgaata tagacaaaat catcagtcaa gagttcttct agttggtttc cttggtcaat
    34681 caattgttca cgcataagca attttttata gacattgtct aaaatttcat cctcaaggat
    34741 aggtgctggt tcgatatgga catcggtatc aaagacgcca aaacgctcct ccagcataga
    34801 ctcgacctga tccgcgattt catggctttc aaaaacagac aagtcaggat tcatctctag
    34861 tgtaatatcc aggtagatgt tgctaccgta ggtgcgacct ctttgcgatt tgaccttgct
    34921 gattttggga atttccatga tagccttttg gtagtcctcg agcaggcggt cgtcaaagcc
    34981 atctgaaaga ctaaaggaag actcgatgaa gatatcatag gcagtcttca agataaagaa
    35041 agtgatgatg atagcaacca gtttatccac aatcggataa ttgaaactac tagctaggat
    35101 ggcaatggcg gttccaagtg aggtaacagc gtcagaaaga ttgtccttag cagctgcctt
    35161 cagcgccttg gagttggatt tcttactgag gcgagtattg tagagataga ccacaaacat
    35221 aatcgctgca gaaatgattc ctagagttgc accaagagga tcaatgaccg tttcttcccg
    35281 actgagaatc ttttgaatgg tatctcttag aacatcgaaa ccgacataga acatgatgat
    35341 agaagtgatc aagcttgcca aatcttcaat cttccaatga ccaaaacggt ggtcacggtc
    35401 tgcaggctgg cgcgccatcc gaatcccgat taagagggct acatttccaa tgatgtccga
    35461 tacgttatta aaaccatcgg ccaccaaact ggatgaatga aggagatgac cagctgctaa
    35521 tttggctgca gacaagatca aataggtcga aatactgata atggctccac gctcagctaa
    35581 cttgagattt gagatagatt gcttcattca acttcctttc tagtcacata gcattctacc
    35641 attatactgg ttttcaagga aaaattcaaa taaggcagtt tttactcttt gaaaactccc
    35701 caaaatttgg tataatggta ctactcaagg gagtagctgg cagaaacctg tgatagtgtc
    35761 gtcattccga attttatgct gaaaagtatg ctttccggcc ctatcttaaa cagcgagact
    35821 tgttatgatt aacaggtctc tttttgtttg tcgtgaaaag atatgacaga aagagagtct
    35881 gttttgcaca caatgtcaag gaggagacac atgtcaaaag aacaaaaacg ccaagcgttt
    35941 tatactcaga gccctgaaga ggtcttgcag gctatggatg cgaccgagca aggtttgtca
    36001 tcaagtgagg cggaaaagcg ccttgccgaa tttgggcaca atgaactcga agaaggcgag
    36061 aaacgatcaa tcttggtcaa attcatcgag caatttaagg atttgatgat tatcatccta
    36121 gttgcggcag caatcttgtc agtcgtgact tctggtgggg aagatatcgc agatgccatt
    36181 atcatcctag ctgtggttat catcaacgct gcctttggtg tttaccaaga aggaaaagct
    36241 gaagaagcta ttgaagccct caaatccatg tctagtccag ttgcccgcgt tcttcgtgat
    36301 ggacacatgg cagagattga ctctaaagaa ttggtaccag gcgatatcgt tgcccttgaa
    36361 gcaggtgacg tggtaccagc ggacctacgt ttgatagaag ccaactctct taaaattgaa
    36421 gaagcagcct tgacaggtga atctgtacca gtcgaaaaag acttgtcagt cgagcttgcg
    36481 acagatgctg gtattggtga ccgtgtcaac atggccttcc aaaactcaaa cgtaacctat
    36541 ggtcgtggga tgggtgttgt tgtcaataca ggtatgtata ctgaagttgg tcatattgct
    36601 ggtatgcttc aagatgcgga tgagactgat acaccactca aacaaaactt gaacaacctt
    36661 tctaaggtct tgacctatgc tatcttggtc attgcccttg ttacttttgt agtgggtgtc
    36721 ttcattcaag ggaaaaatct acttggtgag ttgttgactt ctgttgccct tgccgttgca
    36781 gccattccag aaggacttcc tgctatcgtt accatcgttc tttctcttgg tactcaagtt
    36841 ttggccaaac gacattccat cgttcgtaag ttgccagcag ttgaaacact tggttcaact
    36901 gaaatcatcg cttctgataa gactggtacg ctgactatga acaagatgac agtcgaaaaa
    36961 gtcttctacg atgcggttct acatgactca gctgatgata ttgaactagg tcttgaaatg
    37021 ccactacttc gttcagttgt cttggccaat gatacgaaaa tcgatgtgga aggtaacttg
    37081 attggtgacc caaccgaaac agcctttatc caatatgcct tggacaaggg ctatgatgtc
    37141 aaaggtttct tagagaaata tcctcgtgta gctgaattgc catttgcctc tgaccgtaag
    37201 ctcatgtcaa cagttcaccc attgccagat ggtcgtttcc ttgtagcagt caagggtgcg
    37261 ccagaccaac tcttaaaacg ttgtcttctt cgtgataagg ctggggatat tgctccgatt
    37321 gatgagaagg ttacaaatct cattcataca aacaattctg aaatggctca tcaagccttg
    37381 cgtgtccttg caggtgctta taagattatc gatagtattc cagaaaatct cacttctgaa
    37441 gagcttgaaa atgatttaat ttttactggt ttgattggga tgattgaccc tgaacgtcct
    37501 gaagccgctg aggctgttcg tgtggctaag gaagcgggaa tccgtccgat tatgattaca
    37561 ggtgaccacc aagacacagc ggaagccatt gccaaacgtt tgggaatcat tgacgcaaac
    37621 gatacagaag gtcacgtttt aactggtgct gaactcaatg aactgtcaga tgaagaattt
    37681 gaaaaagtcg ttggtcaata ctctgtttat gcccgtgtgt ctccagaaca caaggttcgt
    37741 atcgtcaagg cttggcaaaa acaaggtaaa gtcgttgcca tgacaggtga cggtgtcaat
    37801 gacgcgccag ctctgaaaac agccgatatc ggtatcggta tgggaatcac tggtacagag
    37861 gtttctaagg gggcttctga tatgattctt gcagatgata actttgcgac tattatcgtc
    37921 gcagtggaag aaggacgtaa ggtcttctca aacattcaaa agactattca gtacctactt
    37981 tctgctaata ctgctgaagt attaaccatc ttcctatcaa ccttgtttgg ttgggatgtc
    38041 ttgcagccgg ttcatctttt gtggatcaac ttggtaacgg ataccttccc agctatcgct
    38101 cttggtgttg aacctgcgga gcctggtgtc atgaatcata aaccacgtgg acgcaaggca
    38161 agcttcttct caggtggtgt tttgagttct atcatttatc aaggtgtact ccaagcagct
    38221 cttgttatga gtgtttatgg ccttgcgatt gcttacccag ttcatgtggg tgacaatcat
    38281 gctattcatg cagatgccct aacgatggcc tttgcaaccc ttggtttgat tcagctcttc
    38341 catgcctaca atgtcaagtc tgtctaccaa tccatcttga cagttggccc attcaagtct
    38401 aagaccttta actggtccat cttggtatcc tttatccttc tcatggcaac aatcgttgta
    38461 gaaccgcttg aaggaatctt ccacgtaacc aaactagact tgtcacaatg gggaattgtt
    38521 atggctggaa gcttctcaat gattatcatc gtcgaaatcg ttaagtttat tcaacgcaaa
    38581 ctcggttttg acaagaatgc gatttaaggg aggtttcgga tgtcagcata tcaattaccg
    38641 accgtatggc aggatgaagc tagtaatcaa ggagctttta cggggctaaa cagaccaaca
    38701 gcaggtgccc gtttcgaaca aaacttgcca aaaggagaac aagcttttca gctttattca
    38761 ctgggaacac caaatggtgt gaaggttact atcttattgg aagaattact agaagctggt
    38821 tttaaggaag cggcttacga cttgtataag attgctatca tggatgggga tcaattcggc
    38881 tcagactttg tgaagctcaa tccaaattcc aagattccag ccttattgga ccagtcaggt
    38941 actgaaaacg taagagtctt tgagtctgct catattcttc tttaccttgc tgagaaattt
    39001 ggagcctttt taccaagtaa tcctgtggaa aaggtagaag ttttgaattg gctattctgg
    39061 caagcaggtg cagcaccttt tctaggtggg ggatttggac atttcttcaa ttatgctcct
    39121 gaaaaattgg aatatcctat taaccgtttt acgatggaag tgaaacgcca gttggattta
    39181 ttggataagg aattggctca gaaaccttat attgcaggca atgactatac gattgcagat
    39241 attgctatct ggtcttggta tggacagtta gttcaaggaa atctttacca aggttctgca
    39301 aaattcttgg atgcctcaag ttatcaaaat ctagtaaaat gggcagaaaa agttgccaat
    39361 cgtccagctg ttaagcgtgg cttggaagta acttatacag aaattaaata gcaaaaaagt
    39421 catcttcgga tggctttttg ctacagttga gggaaagggt ttgcagttat cggcttttgt
    39481 gctataattg ctataatata gtaaaaagca agaggagtgt gaggaagtgg aaaagaaaat
    39541 tgtgaaggat atcttatttt tatctcaagt gtctcagccg gcaagtcagg aggaccttta
    39601 tcttgccaga gatttgcagg atacactctt agcaaatcgt gatacctgtg ttggtctagc
    39661 tgccaatatg attggggtgc agaagcgcgt gattatcttt aatcttggct tggttcctgt
    39721 ggtcatgttt aacccagtgc ttctgtcctt tgaaggatcc tatgaggcag aagaaggctg
    39781 tttgtccttg gtaggtgtga gatcaactaa gcgttatgaa accataaggc ttgcctatcg
    39841 tgacagcaag tggcaggaac agaccattac cttgacaggc ttcccagctc agatttgcca
    39901 gcatgagctg gatcacttgg aaggacgaat catttaggag gaaagcaaat gaaacgaata
    39961 gtctttgaac ttatttttat cgcaacgacc tggtatatct ttttaccgcc ccttaacctg
    40021 accagctggg aatttctctt cttcctctgt gggcatttgt tagttgtggc aatattattt
    40081 ggctttggca aggggataaa ccttgtcaaa acggttcatg tgcgccacgg taaggcggaa
    40141 gctgccttaa atcttgaggg tttcaaaatc aatcggttag ggaaaattct gttagcttcg
    40201 attggaggaa ttcttctctt ggcagctttg gtttccttgg taacttccag catgtttcag
    40261 gctaaaaatt atgccaatgt agtcacggtt acggaaaaag actttactga atttcctaag
    40321 agtgacacca gtaaggttcc tatcctagat agaagtactg ctgaaaaaat tggagaccgc
    40381 tacttgggtt ccctaaccga taaggtgtcg caatacgtag cggcagatac ctatacccaa
    40441 ttgacaattg atgggaaacc ttatcgggtc acaccactag aatatgcaga ccctatcaaa
    40501 tggtttaaca atcaagccaa gggaatcggt gagtatatca aggtggacat ggtaactgga
    40561 aatgcggatt tggtggactt gaagacacca atcaagtatt cagactcgga gtattttaac
    40621 cgtgatgtca aacgtcacct gcgcttgaag tacccgacca aaatctttaa aactccatct
    40681 tttgaggtgg acgatgaggg caatcctttc tatgtagcaa cggtttacca aaagcaattt
    40741 ggacttgcgg ttcctcgtcc tgcttcagtc attatcttgg atgctacaaa tggagaaacc
    40801 aaggaataca gcttatcaga tgttccagaa tgggtggaca ggatctatcc agcagaggaa
    40861 accattgagc aaattaacta caacggcaag tacaaggacg gtttcttgaa tgccatgatt
    40921 tccaagaaaa acgtgaccca gactaccaag ggctataatt acttgtctat cggtaatgac
    40981 atctatctct acacaggtgt gacgtcggct aatgcggatg agagtaatct tggtttcatc
    41041 cttgaaaata tgcgaacagg agaaatcact aagtatagct tggcttctgc gacagaagaa
    41101 tcagcccgtg aatcagcaga aggtgctgtt caggagaaat cctacaaagc aaccttccca
    41161 atcctcatca acctcaatga caagcctctc tacatcatgg gcttaaagga caatgctggc
    41221 ttggtcaaag agtacgccct ggtagacgca gtcgagtacc aaaatgttat cgttgctact
    41281 acagtggaag agatgctcag caagtatgcc aataaaaacg accttgaaat tgacaatgca
    41341 acgacagaaa gcatcaaggg agtagtagca gacctcaaat cagctgttat caagggagac
    41401 actgtctact tctttaaagt tgatggcaag atatacaagg tcaaggcttc agtatccgat
    41461 gaccttcctt accttgaaaa tggtaaaacc ttcgaaggtc aagtaggaaa agacaattat
    41521 ctcaagacct ttaaagtaca ataatactct tcgaaaatct ctagctctat ctgcaacctc
    41581 aaaacagtgt tttgagcagc ctgcggctag tttcctagtt tgctctttga ttttcattga
    41641 gtataaaaaa ggtttattta ataaatatat gttataataa ggtaaattaa gcctaatgga
    41701 ggacaaagaa atgggttttt atttgatggt tgcttcaatg ctactcggac tgctcgcttt
    41761 gaagataggt ttttctcagt tcaaggagaa aaaagataaa ttcttatcta tcttaacaag
    41821 tttagctggc acagcccttg ttctcgtggc tgtctggtta ggatggccca aataaataga
    41881 aaaacctcgg tcaaaccgag gtttttcaaa tgaatttctt ggttgtggct aaaaaatatg
    41941 ctacactatc aatatgaaaa ttttaatccc aacagcaaaa gaaatgaaca cagacttgcc
    42001 aagtatcgag gcaattcctt taaaaccaga aagtcagacc gtgcttgatg ccttggctct
    42061 ctattctgcc agtcaattgg agagtttcta caaggtatcg gctgagaaag cggcggaaga
    42121 atttcaaaat atccaagctt tgaaaaggca aactgctcaa cactatccag ccttgaaact
    42181 ttttgatggg cttatgtacc gcaacattaa gagagataag ctgaccgagg cggaacaaga
    42241 ttatcttgaa aatcatgtct tcattacctc ggctttgtac ggtgttgttc cagccttgtc
    42301 acccatggct cctcaccgtt tggatttttt gatgaaatta aaagtcgctg gtaagacttt
    42361 gaagagccat tggaaggcag tctatgatga agctctgaag aaggaagaag tgattttctc
    42421 tctcttgtca tcagagtttg agactgtatt ttctaaggaa atcagagcaa agatggtgac
    42481 cttcaaattc atggaggata gaggcggtca gctgaagatt cactcaacta tctccaagaa
    42541 agcgcgcggg gcctttctaa cagctttaat agaaaatcaa gtacaaactg tgggggaagc
    42601 acgtcgcttg aactttgctg gatttgttta ccgagaagat ttgtcacaac cacagggatt
    42661 ggtttttgta aaggaagtat agaaatcaga tattttgtat ttggcaatat gtatcatcag
    42721 ctgttttagt ttataaatga gaaaaaaagc gaacaagcta gtcttctgag tgtcagaaaa
    42781 gtagtcttgt tcgcttttat tatgttatac tcttcgaaaa tctcttcaag ccacgtcagc
    42841 gtcgccttac cgtatatatg tcactgactt cgtcagttct atctacaacc tcaaagcagt
    42901 gctttgagca gcttgcggct agcttcctag tttgcttttt gatttttatt gagtgttagt
    42961 tacttgatag cttcgaccaa gtcttgagct tgtttttcaa gtgagtttag gactgtttct
    43021 tcaagaacca attttccgtc tgcccaggca gagtcattaa cacgtgcagc agtgaaatca
    43081 ccaacgcctt gtgtacggat aaatggcaag aggtctttgt agatagcgaa aagttgatcg
    43141 tgccctgcat tggctacaga tgatactgtg acaaacttgt cttgaagggc agaaacgcca
    43201 cgtgtatcag acaagtcaag ggcacgagat agccagtcaa gcaagttttt cactgtacca
    43261 gggatagaga agttgtagac tggagagaaa atccagatag catccgcaac gagaactgct
    43321 tcacgagcag cagctacagc tggatgtgtt ggaacttcca aatcttggct gaagagagga
    43381 agggctgaat aatcaaggta gctaacttcc gctttaccag caagtgcttt ctcagcttcg
    43441 agcgccattt ggtggttgaa agaaccttga cgtagtgatc cgacgataaa taatactttt
    43501 ttagacatga tgtgtctcct ttttcttaaa atttcgagaa ctctctcgtt gttataaaat
    43561 atattacaac aaaacaaaag aacttgcaag aaatttgctc agagtttatt tgaaaattgt
    43621 aaaatttcgg aaactctagt catttgtgac tgaaaaagta agaactgttt cactttcaaa
    43681 atcggttttg tttgaaggga gaaatagaat tggttgctca aagcacagct ttgaggttgc
    43741 agataaagct gacgtggttt gaagagattt tcgaagagta ttcttatatt cacttgtaat
    43801 aaagcttaat agatggtaaa atagacgagt gaaaaaaaga caaaacaaag caaaaaataa
    43861 tctactgtgg cagtatggtc tagggatgac gattttgttt gtggttatca gtgcttcctt
    43921 tctgtatatg gtttctctta gcatgaaacc ctatcaaaca gctaaaagtg aaggagaaaa
    43981 attagctcag cagtatgcag gattagagca ggctgatcag gttgatttat acaatggctt
    44041 ggaatcttat tacagcgttc ttggtcgtaa taaacagcaa gaagcgcttg ctgtcctgat
    44101 tggtaaagat gaccataaga tttacgttta tcagctaaat cagggtattt cacaagaaaa
    44161 agcagaaacg gtttctaagg aaaagggagc tggcgagatt gacaagataa cctttggtcg
    44221 ttatcaagac aagccaatct gggaagttaa gtcaggatct gatttttatc tagtagattt
    44281 tgaaacagga gcattggtca acaaggaggg cctatgaaat tatccaaccg tgttttagaa
    44341 atggaagaaa gtgtgacttt ggctgctgga gcccgtgcca aagcactgaa ggctgagggt
    44401 agagatattt tgtctctaac cttgggtgag ccagatttca ctactcccaa aaatatccaa
    44461 gatgccgcca ttgcatcgat tcgagatggg cgtgcttctt tttatacagt aacctcaggt
    44521 ctgccagagc ttaaggcggt ggtcaatagc tactttgagc gcttttacgg ctattctgta
    44581 gcgtcaaatc aagtgacagt cgctgcggga gccaaatatt ctctctatac cttctttatg
    44641 gctgtggtca atccaggtga tgaagtcatc atcccaaccc catactgggt tagctatgga
    44701 gatcaggtca agatggcaga aggcgttccc gtctttgttt ctgctaagga agacaatcac
    44761 tttaaggtga ccgtagagca gttagaagca gcttgcactg acaagaccaa ggttttggtg
    44821 ctgaattcgc catctaatcc cacaggtatg atttacaccc gtgaggaact cttggcaatt
    44881 ggaaactggg ctgtagaaaa tgatattctc atcctagcag acgatatcta tggccgcttg
    44941 gtttataatg gtcatgagtt cacaccgatt tctagcctat cggaagcgat tcgcaagcaa
    45001 acagtggtca tcaatggtgt gtctaaaacc tatgccatga ctggttggcg gattggttat
    45061 gccgttgggg aagcagacat tatcgctgcc atgtccaaga ttgcaggtca aacaacttcg
    45121 aatccgtcag cagtagccca atatgcagca gttgaggctc tatcaggtga gcaagatact
    45181 gtagaaagca tgcgtcaggc ctttgaggaa cgtcttaata ccatctatcc cctccttgca
    45241 gaagtgccag gatttgaagt ggtcaaaccg caaggggcct tctatctctt cccaaatgtc
    45301 aaaaaggcca tggagatgaa aggctacacg gatgtgacag actttacaac tgttatctta
    45361 gaagaagccg aagtggcctt ggtaacagga gctggatttg gagcaccaga aaatgtccgc
    45421 ctcagctatg cgacagacct agacacgctt aaagaagcag tcgaacgctt gaaagcattt
    45481 atgggtagtg agaatgattg atcattttga gattaaggta aaggatttac aaatttcagg
    45541 aggattttat aggagttttc tcgctccttt ggactataaa ttggctttta agactagttc
    45601 tctaattagt tttctatccc cgaacagccc tcatcctggt ggtgattttt ggctgactca
    45661 aggaacacaa gatcctgttc attttgcttt tttagcagaa aataaggaag aagtttaggc
    45721 ttgttatgag gctggcttag aggcaggtgg gcgagacaat ggggctcctg gttatcgaag
    45781 tgagcgtccg atttactatg ctgcttttat gattgacctg gatgggaaca atatagaggt
    45841 ggtttgccat aaagaataaa aaagaaaagg aaaaataatg acaaaacgtg taacgattat
    45901 tgacgtaaaa gactatgttg gtcaggaagt gacgattggc gcttgggttg ccaacaaatc
    45961 aggaaaaggg aaaatcgctt tcttacaatt gcgtgatgga acagccttct ttcaaggtgt
    46021 ggcttttaaa ccaaactttg tcgaaaaatt tggtgaagaa gtgggacttg agaagtttga
    46081 tgttatcaaa cgcttgagcc aagaaacgtc tgtttatgtg acaggtattg tcaaagagga
    46141 cgaacgttct aaatttggct atgagttgga catcacagac atcgaagtga tcggtgaatc
    46201 tcaagactac ccaatcacac caaaagaaca cggaacagac tttttgatgg ataaccgtca
    46261 cttgtggcta cgctctcgta agcaagtagc tgtgttgcaa atccgtaacg ctattatcta
    46321 tgcaacttat gagttctttg acaagaacgg ttttatgaag tttgacagcc caattctttc
    46381 aggaaatgcg gcagaagatt ctacagaact ctttgaaact gactacttcg gaacgccagc
    46441 ctacttgagc caatcaggtc agctttacct agaagcaggg gctatggctc ttggtcgtgt
    46501 ctttgacttt ggtccagttt tccgtgctga aaaatcaaaa acacgccgtc acttgactga
    46561 gttctggatg atggatgctg agtactcata cttgacacat gatgagtcgc ttgacttgca
    46621 agaagcttat gtgaaagctc ttctacaagg tgttcttgac cgcgcgcctc aagccttgga
    46681 aaccttggaa cgtgatacag aactcttgaa acgctacatt gcagagccat tcaaacgtat
    46741 cacttacgat caagccattg acctcttgca agagcatgaa aatgatgaag atgctgacta
    46801 cgagcatctt gagcatggtg atgactttgg gtcaccacac gaaacttgga tttcaaacca
    46861 ctttggtgtg ccaacatttg tcatgaacta tccagcagcc atcaaggcct tctacatgaa
    46921 accagttcct ggaaatccag agcgcgtgct ttgtgcagac ttgcttgctc cagaaggcta
    46981 tggagaaatt atcggtgggt ctatgcgtga ggaagattac gatgcccttg tcgctaagat
    47041 ggatgaactt ggcatggatc gtacagaata tgaattctac cttgaccttc gtaaatacgg
    47101 tacagttcca cacggaggat ttggtatcgg tatcgaacgt atggtaacct tcgcagcagg
    47161 aacaaaacat atccgtgaag ctattccatt cccacgtatg ttgcaccgta tcaaaccata
    47221 agaacaggaa aacgcccatg tggcgttttt tcgaattcta gtgtttttac ttgcgtaaaa
    47281 aaattttttc tagtataata gtttattgtg agcgaacctc acttacccct tgcaaagtct
    47341 tggggtcatt agaccaaaag gaggaacata tcaatggcta aatacgaaat tctttatatc
    47401 attcgtccaa acattgaaga agaagctaaa aacgctttgg tagcacgttt tgactctatt
    47461 ttgactgaca acggtgcaac tgttgttgaa tcaaaaactt gggaaaaacg tcgtcttgca
    47521 tacgaaatcc aagatttccg tgaaggactt taccacatcg ttaacgttga agcaaatgac
    47581 gatgcagctc ttaaagagtt tgaccgtctt tcaaaaatca acgctgacat tcttcgtcac
    47641 atgatcgtca aaattgacgc gtaagaaggt aaactatgat taacaatgtt gtacttgtag
    47701 ggcgtatgac acgtgacgct gaattgcgtt ataccccatc aaatgtagca gttgcgactt
    47761 ttactcttgc agtaaaccgt acatttaaga gtcaaaatgg tgaacgtgag gctgatttta
    47821 tcaatgtcgt tatgtggcgc caacaggctg aaaatcttgc taactgggct aaaaaaggct
    47881 cacttatcgg ggtgacaggt cgtatccaga ctcgtagtta cgataaccag caaggacaac
    47941 gtgtctacgt gacagaggtc gtggctgaga atttccaaat gttggaaagc cgtagtgtgc
    48001 gtgagggtca cacaggtgga gcttactctg caccaactgc aaactattca gcacctacaa
    48061 attcagtacc agacttttca cgtaatgaaa atccatttgg agcaacaaac ccattggata
    48121 tttcagatga tgatttacca ttctaatgga caactaaatt tataaaggag aaaaaacatg
    48181 gctcaacaac gtcgtggcgg attcaaacgc cgtaaaaaag ttgattacat cgcagcaaac
    48241 aaaattgaat atgttgatta caaagatact gagcttctta gccgtttcgt ttcagaacgt
    48301 gggaaaatcc ttcctcgtcg tgtaacagga acttcagcta aaaaccaacg taaagtaaca
    48361 acagctatca aacgcgctcg cgtaatggct ttgatgcctt tcgtaaacga agattaaaga
    48421 aaagacccag ttgggtctct ttttcatgag cttgaaaaca agaaagcgaa ttaagacccc
    48481 aacgggtctt ttttcacaag ctttgaaatg agagagcgag ttaggctcag tggctccctt
    48541 tttacgagtt tgaaaacaag agaacacatt aaaagcacga tggagctttt tcataaatat
    48601 gtctcttttc tcatccaaga aattaaaata aaaatgataa actttttgaa aataggggat
    48661 ttgcctactt tatgatataa tggaaagagt tagattgaaa gaggtagtga gatggacgcg
    48721 aaattaagat acaaggcaaa gaagatcaag attgtctttt ttgatattga tgatacattg
    48781 cggaattcaa agacagggtt tattccaact acaattccca ctgtttttaa acagttgcgt
    48841 gaaaaaggaa ttttaacagg aatcgcctct ggacgtggca tttttggtgt tgttccagag
    48901 attcgtgatc tcaagcctga cttttttgta actttgaatg gggcttatat cgaagataaa
    48961 aaaggtcagg tcatttatca gcatcagatt gaaaagtcag atgttgagga gtatatctct
    49021 tgggctaagc aagaaggaat tgagtatggc ttggttggga gtcatgatgc caagttgtcg
    49081 actcgcaccg atatgatgag tgaagctatc aatccaattt atcccgactt agatgtagat
    49141 cccgatttcc atgaaaaaga agatatctat cagatgtgga cttttgaaga taagggagat
    49201 gacttgcact tgcctgacag tctctcagac aaacttcgca tggttcgttg gcatcaacat
    49261 tcgtctgata ttgtgccgat ttcaggctcc aaagcgacgg gggtggaaaa ggttgtggaa
    49321 caccttggct tgaaaccaga gaaggtcatg gtttttggag atggtctcaa cgacttggaa
    49381 ctctttgatt atgctggaat cagcgttgcc atgggaattt ctcatgataa aatcaaagaa
    49441 aaagcagatt atattacaaa aacattagaa gaagatggca tttttgctgc cttagaagta
    49501 tttggtatgg tagaaaaaga attgcatttt ccacaagtag acattgaaac agtagaaggt
    49561 cctcttgcga ctattaagac caatcacgga gacttacgta tcaagctttt ccctgaacat
    49621 gctcctaaaa cagtggctaa ctttgtatct ctttcaaaag atggctacta tgatggtgtc
    49681 attttccacc gtattatcaa ggactttatg atccaaggtg gagacccaac tggaactggt
    49741 atgggtggcc agtcaatcta cggcgaatct tttgaggatg aattctcaga agagctttac
    49801 aatatccgtg gtgctctttc catggcaaat gctggtccaa ataccaacgg cagccagttc
    49861 tttatcgtgc aaaaccaaca cctaccttat tctaagaaag aaattactcg tggtggttgg
    49921 ccagaaccga ttgcagaaat ctatgccaat caaggtggga cacctcacct agaccgccgt
    49981 cacacggttt ttggtcagtt agctgatgaa gcatcttacg ctgtcttgga tgccattgct
    50041 gctgttgaga caggagctat ggacaagcca gttgaagatg ttgtaattga aactattgaa
    50101 atcgaggact aagatgaaaa tcggtgataa gctaaagggg cgtattacag ggattcagcc
    50161 ctacggtgcc tttgttgagt tagagacggg tgatacgggg ctgattcaca tttcagaaat
    50221 tcggacagga tttattgaaa atattcatga aaccttgaaa gtcgatgaag aggttcaagt
    50281 tcaggtagtg gatttagatg aatttacggg gaaagccagt ctttctatcc gcactttgga
    50341 ggaagaaaag taccagtttc ctagacggag acgcttttca agcgaccgct ttaactacgg
    50401 ttttgctccc tttcgacgaa tgctaccaat ctggactgga gaagccctgc accatttaaa
    50461 aaagaagaag tagtttagag ttttatattt tttgtaatgt taatatgaat ttgctataat
    50521 aggaccatgg aagaagaaca attattaaaa tcaggagagc gcattaacca gctcttttcg
    50581 acagatatca aaatcattca aaatagagag gtttttagct attcggtgga tagtgttctc
    50641 ttatcacgat ttccacgttt tcctaagaag gggttgattg tggatttctg tgctgggaat
    50701 ggagcagtgg ggctttttgc tagcactcgt actcaagcac agatattgtc tgttgagatt
    50761 caggagcgtt tggcggatat ggctgaacgc tctgtccgtt tgaatggatt agaggagcaa
    50821 atgcaggtca tctgcgatga tttgaaaaat atgcctgctc acattcaggg gagtaaggtg
    50881 gatatgattt tgtgtaatcc accctatttc aaggtggatc cttattctaa tctgaacgag
    50941 agtgaacatt atctcttggc tcgacacgaa atcacgacta atttggaaga aatctgtcgt
    51001 agtgcccaga gtattctcaa gtctaatggg cgtttggcca tggttcatcg tcctgatcga
    51061 cttctggata ttttggatac gttaaaacga cataatctag cccctaagcg cctgcagttt
    51121 gtttatccaa aaagagaaaa ggaagccaat atgcttttga ttgaggcgat caaggatggc
    51181 tcaacaagtg gctttaaggt cttacctcct ttgattgtcc acaatgatga tggctcttat
    51241 acgcccgaaa tcgaagagat ttattatgga tcataaggct tatatgtacg ttctggagtg
    51301 tcgtgatgga tcctactata taggctatac gactgatatg agaagacgcc tcgctatcca
    51361 caatagtggg aagggagcca aatatacacg agcacgcttg ccagtcaaac ttatctatgc
    51421 tcaaggtttt gccagtaagg aagaagccat gtcggctgaa gctcttctca agcgtaagaa
    51481 gaggccacag aaggaagaat ttttatctga aaatcaagat agaaatttac tcagttattt
    51541 tgaagaatcg tggggagtcc tttgactcct cttacctttg tcaaaaagcg aaaaaaatgc
    51601 tacaataaag aaaataaaca aaatgaggta ttatcatgtc caagattcta gtatttggtc
    51661 accaaaatcc agactcagat gccatcggat catctgtagc ttttgcctac cttgcaaaag
    51721 aagcttacgg tttggatacg gaagctgttg cccttggaac tccaaatgaa gaaacagcct
    51781 ttgtcttgaa ctattttggt gtggaagcac cacgtgttat cacttctgcc aaagcagagg
    51841 gggcagagca agttatcttg actgaccaca atgaattcca acaatctgta tcagatatcg
    51901 ctgaagtaga agtttacggt gttgtagacc accaccgtgt ggctaacttt gaaactgcaa
    51961 gcccacttta catgcgtttg gagccagttg gatcagcgtc ttcaatcgtt taccgtatgt
    52021 tcaaagaaca tggtgtagct gtgcctaaag agattgcagg tttgatgctt tcaggtttga
    52081 tttcagatac ccttcttttg aaatcaccaa caacacaccc aacagataaa atcattgctc
    52141 ctgaattggc tgaattggct ggtgtgaact tggaagaata tggtttggca atgttgaaag
    52201 ctggtaccaa cttggctagc aaatctgctg aagaattgat tgatatcgat gctaagactt
    52261 ttgaactcaa cggaaataat gtccgtgttg cccaagtgaa cacagttgac atcgctgaag
    52321 ttttggaacg ccaagcagaa attgaagctg caatgcaagc tgccaacgaa tcaaacggct
    52381 actctgactt tgtcttgatg attacagata tcgtcaactc aaactcagaa atcttggctc
    52441 ttggtgccaa tatggacaag gtcgaagcgg ctttcaactt caaacttgaa aacaatcatg
    52501 ccttccttgc tggtgccgtt tcacgtaaga aacaagtggt acctcaattg actgaaagct
    52561 ttaatgcgta agattttggg ggtcagctca aaatcggaaa gtctagtttg ccttatatcg
    52621 aaaggagttt cggctccttt tttctaggag tgaagtatgt tagaaaatgg cgatttgatt
    52681 tttgtgagag atgggtcaga catgggacag gccatccaga cttccacagg taactatagc
    52741 catgttgcca tttatttgga tgggatgatt tatcatgcta gtggacaggc tggtgttgtc
    52801 tgtcaagaac cggcagactt ctttgagtcc aatcatttat acgacctcta tgtttaccca
    52861 gaaatggata tccagtcggt gaaggaaaga gcttgcaaac atcttggagc accctacaat
    52921 gcttctttct atccagatgc agctggtttt tactgctccc agtatatagc agaaatccta
    52981 cctatttttg aaactattcc tatgaaattt ggagatgggg agcaggagat tagtgatttt
    53041 tggagggagt attacataga actaggtctg cctgttcctc tgaaccaagc tggtaccaat
    53101 cctagtcagt tggcagcatc gcctctgtta caatgtaaag aaaggaatct tcatgattca
    53161 gatttttaat tcatctcgtt tgacgagaca gccatttttg gagaattgat ccgctatctg
    53221 gatcagtatg aggatgtgat tctacgggaa attaaggctc aatttccaga tgttgcagtt
    53281 gataaactca tggaagagta tataaaggca ggcttgattc tacgtgaaaa taagcgctat
    53341 tacctcaatt ttcctacgct tgaatcactt gatagtcttg aactggatca agagattttt
    53401 gtcagagaag ctagtccggt ctatcaagcc ttgttggagc agagttttga gacggaattg
    53461 cgcaatcaaa tcaatgcagc tattttagtt gaaaagacgg actttgcgcg cattaaaatg
    53521 accctgtcca attattttta caaggtcaaa cagcagtatc ctttgacaga aaaacagcag
    53581 gagctctatg acattttagg agatgttaat cctgagtatg ccctcaagta tatgacggct
    53641 tttttgttga aatttctcaa aaaagaccag cttatgcaga aatgccgtga tatctttgtg
    53701 gacagttagg ttgtcttagg ctatattgtg caaaatgaag atggaaagta tgagttggct
    53761 atcgattttg ataaggagag gttaactttc tacttagcgt gatttcttgt ttctgagtac
    53821 attgtttgac tttccttagt attcggtata aactatatgt aaccggtaac acatatcgga
    53881 ataaactaaa ggagacaatc atatgtcact tgaaaacaaa ttggaacaag caacaggcgc
    53941 tgtcaaagaa ggttttggta aagttactgg agacagcaag acagaacttg aaggagctgt
    54001 tgaaaaaaca gtttctaagg caaaagacgt tgtagaagac gcaaaaggtg ctgtagaagg
    54061 tgccgttgaa ggtttgaaaa acgtttttac taaataatag gaaaaaatca agggtttcat
    54121 tttcccttga ttttttctat tcttataaat aattttctgc gacggctgta tctcctgggt
    54181 aggattcttt cttgccctgg atgatttggt aacaatcggc tcccttaccc gcaataataa
    54241 ctgcatctaa ttcgtgattt gtgatagcca ttgccgcctt gatggcttct tggcgatccg
    54301 caatcttctc aacaggatga ttgatgtagc tactaatttc atctgcaatg gccattgggt
    54361 cttcatagtt agggtcatca gcagtcagaa agacttgaat ctcagggtgt tgattgagga
    54421 ggaggccaaa gtccttacga cgactttctc ccttgtttcc tgttgatccc agaaccagag
    54481 caatctttcc ggtttgatga gtttcaacca cattgatgag ttttttcaga ctatccccat
    54541 tgtgggcata gtcgatgaag accttggctc catttttctg agtgaggact tccatacgac
    54601 caggaacgcg ggttgcagcg atgccttttt tgatgtcctc aagacttgct ccgagacgga
    54661 gacaagcaag tccagcagca actgcatttt cttggttgaa gttgccaatg agttggatat
    54721 cataatctcc agcgagttta cccgtagctg aaaatctaaa ggctttggaa ttctcgattt
    54781 ggttatcaaa ttggctacca tagaaatcat ggtcttgatc ttcaacctgt tctttcaaga
    54841 ctgagaagtg gtccatgtca ctgttaatga tgactgctcg gctattttcc atcaagagac
    54901 gcttgtggta gaaatagtct tcaaagctag ggtgttcaat cgggccgata tggtctaggc
    54961 tgatatttag gaaaactccc acatcaaagg ttagaccata gacacgtttg accagatagg
    55021 cttgactgga gacttccatg atgaggtggg tacggtcatt ttgcacagcc tgattcatca
    55081 tgtcaaagag gtcaatactc tcaggggttg tcaacgctga cttaaagaaa gtctctccat
    55141 caagagttgt gttcatggtc gacaacatag caggtcgatg cccttgagat aagatgttat
    55201 aggcgaaata ggctgctgtt gtcttaccct tagtaccagt aaaggcaagg agtttgagtt
    55261 tttcctgtgg attaccatag aactccatgg caatcaaact catggctttc tttatatcgt
    55321 tcacaatgat gacagggata ccgacttcgt agtccttttc agctatatac caagctaagc
    55381 cttgtgttat agcagaaaga aggtattctt ttttaaaggc agcgcctttt gcaaaaaaaa
    55441 gagtgtcttc tgttactttt cggctgtcgt agctgatgct atcaaaaaca actttgctgt
    55501 agttgtagtg gtaatgacct tggtcaataa tttcgcgaaa aaggccatct ttctttaaaa
    55561 tatctaatac agtttcaatt tttatcatac tttctattgt aaaccgaaag tcgcaaattt
    55621 acaagtgaca aggaaaagtt tataatggaa gataaggagt ttttcctagt tatcaaaatt
    55681 gaatgaggaa tctatgtcgc acgaaaacaa tcaccagcag gcccagatgt tacgggggac
    55741 tgcttggcta acggctagta actttatcag tcgcctactc ggggctgttt acattatccc
    55801 ttggtacatc tggatggggg cttatgcagc taaggcaaat ggtctcttta ccatgggtta
    55861 caatatctat gcttggttct tgttggtttc aacagcgggg attccagttg cggtggccaa
    55921 gcaagttgcc aagtataata ccatgcgaga agaagagcat agctttgccc tgattcggag
    55981 cttcttaggc tttatgacag gactaggcct ggtttttgct ttagtcttgt atgtctttgc
    56041 tccttggcta gcagacttgt ctggcgtggg caaagacttg atcccaatca tgcaaagctt
    56101 ggcttgggga gtcttgattt tcccgtctat gagtgttatc cgaggatttt tccaagggat
    56161 gaataacctc aaaccctatg ccatgagcca aattgctgag caggtcattc gtgttatctg
    56221 gatgctccta gcaaccttta tcattatgaa gctcggttca ggagattatc tagcagccgt
    56281 tacccaatca acctttgctg cctttgtcgg tatggtagcc agttttgcag tcttgattta
    56341 tttccttgcc caagaaggtt cactcaaaag agtctttgaa acaggagata agattaacag
    56401 taagcgtctc ttggttgata ccattaagga agccattcct tttatcctga cagggtctgc
    56461 catccagctc ttccagattt tggatcagct gacctttatc aatagtatga gctggtttac
    56521 caactacagc aatgaggact tggttgtcat gttttcttat ttctcagcca atcctaataa
    56581 aatcacgatg attttgattt ctgtaggggt ttcgattggg agtgttggtt tgccactttt
    56641 gacggaaaac tatgtcaagg gggacttgaa agcagcttct cgtctcgttc aggacagtct
    56701 caccctactc tttatgttct tgctaccagc aacagttgga gtggttatgg taggagaacc
    56761 tctttatacg gtcttctatg gtaagccaga tagtttggct ctgggcttat ttgtctttgc
    56821 agttttgcag tctattattt taggcttgta catggtcttg tctccaatgc ttcaggccat
    56881 gttccgcaac cgcaaggccg ttctctattt tatctatggt tctattgcca agctagtctt
    56941 gcaactacct accatcgccc tcttccacag ttatggtcct ttgatttcaa caaccattgc
    57001 tctcatcatt cctaacgtct tgatgtatcg ggatatttgt aaagtaactg gtgtcaagcg
    57061 caaggtgatt ttgaagcgaa ccattttaat cagtttgctg accctagtca tgtttctgtt
    57121 aataggaacc atccagtggc tgttaggatt tttcttccaa ccaagtggac gtttgtggag
    57181 cttcttttat gtagctcttg tcggtgccat ggggggtgga ctttatatgg ttatgagtct
    57241 gcgtacctat ttgttagata aggtaatagg aaaagcccaa gcagatcgcc tgcgagcaaa
    57301 atttaagctt tcgtaaggta gcatttataa ataaaaggaa taagttgaac aatcttttag
    57361 gagaacttga aacttattcc ttttttagcg taaaaatagc taaaattatc tttcaaaaat
    57421 agaaaatgag gtttttttcg attttttgga aaaataattg actaaacaaa ccaaacgttg
    57481 tataataaaa caaatattta aagcaggagg ttctggaaat gaaaaagtct aagagcaaat
    57541 atctaacctt ggcaggtctt gtcctgggta caggagtttt attgagcgcg tgtggaaatt
    57601 ctagcacggc gtcaaaaacc tacaactatg tttattcaag tgatccatct agcttgaact
    57661 atctagcaga aaaccgcgca gcaacatccg atattgttgc aaatttggta gacgggttat
    57721 tagaaaatga ccaatatggg aatattattc catcattagc agaggattgg actgtttctc
    57781 aggacggttt gacctatacc tacaaacttc gtaaggatgc caagtggttt acttctgagg
    57841 gagaagaata tgcgcctgta actgcccagg attttgtgac aggtttgcaa tatgcagctg
    57901 ataaaaaatc agaagccttg tatctagtgc aggactctgt tgctggtttg gatgactata
    57961 tcactggtaa aacaagcgac ttttcaactg tcggtgtcaa ggcacttgat gaccaaacgg
    58021 ttcaatatac tttggttaaa ccagaacttt actggaattc aaaaacactt gcaacgatac
    58081 tttttcctgt taatgcagat ttcctgaaat caaaagggga tgattttggg aaggcggatc
    58141 catctagtat tttgtacaat ggacctttct tgatgaaagc acttgtctca aaatctgcta
    58201 ttgaatataa gaaaaaccct aattactggg atgctaagaa tgtctttgta gacgatgtga
    58261 aattgaccta ctatgatggt agcgaccaag aatcactgga acgtaatttt acagctggtg
    58321 cttatactac ggctcgtctt tttcctaaca gctccagcta tgaagggatt aaagaaaaat
    58381 acaaaaacaa tatcatatat agtatgcaaa attcaacttc atatttcttt aattttaacc
    58441 tagataggaa gtcttacaat tatacttcta aaacaagtga cattgaaaag aaatcgactc
    58501 aggaagcagt tctcaataaa aacttccgtc aggctatcaa ttttgctttt gacagaacat
    58561 cttatggggc tcagtctgaa gggaaagaag gtgcaacaaa gattttgcgt aacctagtgg
    58621 ttcctccaaa ctttgtcagt atcaagggaa aagactttgg tgaagttgta gcctctaaga
    58681 tggtcaacta tggtaaggaa tggcaaggta tcaactttgc ggatggtcaa gacccttact
    58741 acaatcctga gaaatccaag gctaagtttg cggaagctaa gaaagaactc gaagcaaagg
    58801 gtgttcaatt cccaatccac ttggataaga ctgtggaagt aacagataaa gtaggcatac
    58861 aaggagttag ttctatcaaa caatcaattg aatctgtttt aggttctgat aatgtagtga
    58921 ttgacattca gcaattaaca tcagatgagt ttgacagttc aggctacttt gctcaaacag
    58981 ctgctcagaa agactatgat ttatatcatg gcggttgggg acctgattat caagacccgt
    59041 caacctatct cgatattttt aatactaata gtggaggagt tctacaaaat cttggactag
    59101 agcctggaga agccaatgac aaggctaagg aagttggact ggatgtctat actcaaatgt
    59161 tggaagaagc taataaagag caagatccag ccaaacgtta tgagaaatat gctgatattc
    59221 aagcttggtt gattgatagt tctttagttc ttccaagtgt ttcgcgtggg ggaacaccat
    59281 cattgagaag aaccgtacca tttgctgctg cctatggttt aaccggtaca aaagggattg
    59341 aatcatataa atacctcaaa gtacaagata agattgtcac aacagacgaa tatgcaaaag
    59401 ctagagaaaa atggttgaaa gaaaaagaag aatccaataa aaaagcccaa gaagaattgg
    59461 caaaacatgt caaataaaat ctaattgtag ataagtttgt gtaagaagtc tttgtgctta
    59521 aaaacgcata atatcaggta tataaaatcc tagatgttat gcgttttgtt ataggaagat
    59581 ttattagatt ttatcctcaa attgagttat tcccgacttt atccgttgaa atattataag
    59641 gagtatttat gaaattaaaa ttattaagag tagatactaa ggtgattatg gggagtttct
    59701 tccttgttct gtctagtcta cttgctttgt tgcttcccct tatcttaaaa ggtttaatag
    59761 atgggagttc tattgaaaat ataggttcca aagtatttca atcgtttttg atttttattg
    59821 gtcaagcctt gttttcttct attggttact atctgtttag tcaatcgggt gaaaaaaaga
    59881 tagcaaaaat caggaaaaaa gtgatagagg ggttgattta tgcagagaaa tccttctttg
    59941 ataagagcca aagtggggag ttgacttctg ccattgtcaa tgacatgagt gtcattcgtg
    60001 agtttttaat tacgactttc ccaaatatta ttctgagttt agttatggta cttggttcca
    60061 ttgtagtctt atttagtctt gattggaatc tttctctact tttattcatc actcttcctt
    60121 gtatgatgtt tattatcttg cccctttcca atatcagtga aaagtatagt cgtcgtttac
    60181 aggaggaaat cggattttta acagggcaat tgactgaaaa gattcaagaa catgaattaa
    60241 ttaagactaa ccaagcagag aaaagtgtac aggatgtttt ggataattgt attgaaaggg
    60301 tacaaaacaa ttcactgaaa tcagataggg ttacttcttt tgagaccccg tttgctctct
    60361 tatttatctt tgcgactata gctgtgatgc taacctatgg gggttatcgg gtcagcgcag
    60421 gatatatatc tgtgggaacc ttggtttcgt ttttgattta cctctttcaa ttacttaatc
    60481 ctattagtaa tatagctaat tttgtaactg tttattctag gagcaaggga tcttcagttg
    60541 cactggagaa cttgcttgca gttcctaaag aaaaatttga gggaggaaaa tcggtatcag
    60601 gataaaggtt gaattttaac catgtctatt ttggttatga tgaaaatcga cctgtcttaa
    60661 aggatattac ttgttcaatt ttcaagggga aaaaaattgc ttttgttgga ccatctggat
    60721 caggaaaatc aacgattgtg cgtttgttag agcggtttta taaaccgctt tcaggagata
    60781 ttctaatgga gcaatcaagt atatatgatt ttaacttaaa agaatggaga agtaaaatcg
    60841 cttgggtttc acaaaataat gcagtcttat ctggcagtat tcgtgacaat ctttgtctcg
    60901 gtttgaatcg cttagtaact gatgatgaat tgatgaaagt gctagactta gtatcactag
    60961 gtgatgagat tcgctccatg aaagagggac tagatactga agttggtgaa cgcggacgat
    61021 tcttgtcagg ggggcaaagc caaagacttc aaatagctag agcctactta aaagatgctg
    61081 aaattcttat atttgatgaa gccactgcta atcttgatgc ggattctgag tatgcgatta
    61141 tcagtagcct ctattctgta ttaaaggaga agacggttgt gattatagcg catagtttgt
    61201 caacggtaaa agatgtggat tgtattttct tcttagagga ggggaaaatc actggctcag
    61261 gaactcataa ggaactactg gaaaatcatg agcgttatgc tcgttttgtg caggagcaaa
    61321 tgatagagtg aagtgtcttt tgagattcac cattttatag tctattaaag ggagcaggaa
    61381 aaactccctt tttatatagt ttgaaactat aactagctct tgaaaagaag aaaatgagtt
    61441 gatgaaaata agtggtacaa tagttactat agatttggag gtattgtatg agcaaggaat
    61501 tacacattaa cacaattttg gcccaggcgg gtattaagtc agatgaagcg acaggtgcat
    61561 tggtgacacc gcttcatttt tcaacgacct atcagcatcc agagtttggt cgatctactg
    61621 ggtttgacta tacgcgcact aaaaatccaa ctcgtagtaa ggctgaggaa gtcttggcgg
    61681 ctattgagtc agcagactat gccctagcga ctagctcagg gatgtcagct attgtactgg
    61741 cctttagcgt ctttccagta ggaagtaagg tcttggcagt gcgtgatctt tacggtggtt
    61801 cttttcgctg gtttaaccaa gtggagcagg aaggtcattt ccattttacc tatgccaata
    61861 cagaagaaga gttgattgcc gagttagaaa aggatgtgga tgttctctat atcgaaaccc
    61921 caaccaatcc cttgatgttg gaatttgata tcgaaaaact agcaaaattg gctcatgcta
    61981 agggtgccaa agtggtggtg gacaatacct tctacagccc tatctaccaa cgtccgattg
    62041 aagatggagc agatatcgtt ctccattcag caaccaagta tctagcaggc cacaatgatg
    62101 tcttggctgg agtggttgtg accaatagtt tagaactata cgagaagctt ttttacaatc
    62161 tcaatacaac aggggcagtc ttgtctccat ttgacagcta ccagttgctt cgtggtctca
    62221 agactttgtc tcttcgtatg gagcgctcaa cagctaacgc ccaagaagtg gttgcctttt
    62281 tgaaggattc tccagcagtt aaggaagttc tctacactgg tcgtggaggc atgatttcct
    62341 ttaaagtagc cgatgaaaca cgcattcctc atattttgaa cagtctcaag gtcttctctt
    62401 ttgcggaaag tttgggtgga gtggaaagtc ttattactta tccaacgact caaactcatg
    62461 ctgatattcc agcagaagta cgccattctt atggtttgac agatgacctc ttgcgtttgt
    62521 ctattgggat tgaggatgct agagatttga ttgcagattt gcgccaagcc ttagaaggat
    62581 aagacaaaga tgggaaaata tgattttaca agcctgccca accgtttagg gcaccatacc
    62641 tataaatgga aagaaacaga aacggatagt gaagttctac cagcttggat agcggatatg
    62701 gactttgtgg tcttgcctga aatccgccaa gccgtgcaaa cttacgcaga ccaactggtt
    62761 tatggttata cctatgccag tgaagactta attaaggaag ttcaaaagtg ggaagctaca
    62821 caatacggtt acaactttga caaagaggct cttgtcttta tcgagggtgt ggtaccagcc
    62881 atctcaacag ctattcaaac ctttacaaaa gaaggcgagg cggttttaat taacacgcct
    62941 gtctacccac cctttgctcg cagtatcaag ttgaataatc gtagattgat tactaattcc
    63001 ttagtggaaa aggatggtct gtttgagatt gactttgacc aacttgaaaa ggatttggtg
    63061 gaagaggagg ttaaactcta tattctttgc aaccctcaca atcctggtgg acgtgtttgg
    63121 gaaaaagaag tgttggagaa gattggccaa ctctgccaaa aacacggtgt tttgttagtt
    63181 tcggatgaga ttcaccaaga tttgaccctc tttggtcaca aacaccagtc tttcaatacc
    63241 atcaatcctg ccttcaaaaa ttttgctatc gtcttgagca gtgccactaa aacatttaat
    63301 attgctggaa caaaaaattc ctatgcagtc attgaaaatc ctaagttgag actggctttc
    63361 cagaaacgcc tgttggccaa taatcagcat gaaatttcag gcttgggtta tttggcgaca
    63421 gaagctgcct atcgatacgg taaagattgg ctagaggaac tcaagcaagt ctttgaagac
    63481 cacatcaatt atgtggtgga tctatttgga aaagagacta aaatcaaggt catgaaaccg
    63541 caaggtacct acttgatttg gcttgacttt tcagcttatg acctgactga tgaaacattg
    63601 caagagttgt tgagaaatga agccaaggtt atcctcaacc gtggtttgga ttttggagag
    63661 gaaggaagtc tccatgcccg catcaatata gctatgccca aatctctgtt gcaagaagtc
    63721 tgtcagcgga ttgtggctac ttttgccaaa cgttaaaaat ccagccttct aggagaaaag
    63781 tcttcctaga aggctatttt cataggagaa aatatggtat aataaaaaga taaggtaaag
    63841 gtgaaaatat ggctaaattg attccgggga aagttcgtat cgaaggtgtt gccctttatg
    63901 aaactggtaa ggttgatatc atcaaggaaa agaacaatcg gctctacgct cgcgttgcag
    63961 aagaagaact gcgctatagt ttagaggatg atttggtttt ttgtgcctgt gatttttttc
    64021 aaaagagggg ctactgtgtg catttggcag cgctagagca ttttctgaaa aatgatgagc
    64081 gtggtcagga aatcttgtgg agtctggaag aaggtcatga agaaaaagag gctgttgaaa
    64141 ccaaggtgac cttgggtggc aagtttttgg atcgaatttt atctccaaaa tcagaatgcg
    64201 cctatgagtt atcagctgtg ggtcaggtgg aagcaggaac caatcatatc ttgtggactc
    64261 tgagaatcgg ccaaatcaat agccaaaaat actatgtcat tcgggatatt ccactttttt
    64321 taaggattgt cgagcagaga aagtcgtata tgattggcaa gatttatgag gagtctcttt
    64381 cttgggaagc ctttgatgat gccagccaag aacttttgac tttcttgcac ggactaacgg
    64441 aggaagggct ggttccagac ctctttttcc aaaaccaagg tcggcacctc tttttccctc
    64501 tgaccttttt tgagcagggt gtgaatttac tgatggcctt gccccatttt caatttgacc
    64561 atcaagtgga tagctaccaa accctgcttt ttcaggatat gcatgctgat gccaatctat
    64621 ttgcctttac agtaacagaa tactcggatt attttgaaat ggaaatcagt gagagtccta
    64681 gggttaatgt cttttatcag ggagcagtac ttttccataa aggtcaggtt tattttttaa
    64741 cagaccagca gatgcgtctt ctcaaggaaa ttaaagtgtt acctgtgggt caacaaggaa
    64801 agaaatactt gcaatttgat agcagtgatc gagacaaatt ggcctcctgt ctgactcttt
    64861 ttatccagat gggcaccgtt tcagctccag aacgtctaca aatcaaaact tttgcgccct
    64921 ctttttactt tgacagggaa aaagataatc ggattcgttt agaaattcag tttgattatg
    64981 gaaatagaca ggtatctagc cgacaagagc tagaagaatt accattttca agtgacgcgg
    65041 acttagaaga aagaattttc caagtctgtt tggctgcggg ctttgaagcc gattttcaat
    65101 cttggcgtca ggccttaaaa gcggagtctg tctatcattt ttttcatgat atcattccag
    65161 tctttgaaaa actcgggcat gttgacctat cagataaact agaagagctt tatagcctag
    65221 cgagtcctca ggtgcagatt gcctccaagg gaggtctctt ggaaatccag tttgattttc
    65281 aaaatattgc ccaggaggaa atcgaccaag ccatgcaggc cttggttgcc aatcaggatt
    65341 tttatattga ttcgtctaat caagtttact ttttcgatga agaaaccaag aaaattcggc
    65401 aaaatctaca ggaactgggg caatttgaat taaaagatgg gaccttgcag gctcggaaat
    65461 ccttggccta cagtttagct catctctttg aagggcgaga ccgtgtttct ttttcacaag
    65521 aattccagaa tctggcccag gatttgacac atccagagga ctttcctcga caggcaactc
    65581 aggttcaggc tgacttgcga gattatcagg aaaagggaat tggctggttg cagatgctcc
    65641 atcattatgg ttttggtggg attttggctg atgatatggg acttgggaaa acccttcaga
    65701 ccattgcttt tttgactagt caagtgacaa aagaaagtcg ggttttgatt ctcgctccgt
    65761 caggtttgat ttacaactgg gcagatgagt ttcagaaatt tgccccacag ttggatgtgg
    65821 ctgttgttca tggtttgaaa gcaagtcgtg aggagattct tgccgagagc catcaaatct
    65881 atgtgactag ctatgccacc ttccgtcagg acagtgagtt ttatcagggg atggcctttg
    65941 acttcctttt cttagatgag gctcaggtca tgaaaaatgc ccagaccaag attgcccaga
    66001 ccttgagaca atttgtggtg ccgtcggtct ttgccttgtc aggaactccg attgaaaacc
    66061 atctgggtga gttgtggtct attttccaaa tcgtcatgcc cggacttttg ccaagcaaga
    66121 aagaatttat gaaattgcca gcagagcgag tggctcagtt tatcaagcct ttcgtgatgc
    66181 gacgcaagaa agaagaagtt ctgactgaat tgccagactt gattgaggtg gtttataaaa
    66241 atgaactgga agaccagcaa aaggctattt accttgccca gttacaacag atgcgagacc
    66301 atctggctca agtgtcagaa caggaatttc agcgaagtcg tgtggaaatt ttatctggtt
    66361 tgatgcgctt gcgtcaaata tgtgacactc ctgccctgtt tatggaagat tatcagggag
    66421 ccagcggcaa actagatagt ctccgagacc tactggtaca ggtggcagac ggcggacacc
    66481 gtgtcttgat tttctctcag ttcaagggaa tgttggaaaa aattgaacaa gaactgccag
    66541 acttgggcct gacatccttt aaaattacgg gttcaacccc agccaaggaa agacaagaca
    66601 tgaccaaggc ctttaaccaa ggagaaagag atgcctttct gatttccctc aaggctggtg
    66661 gggtcggtct gaacctgaca ggtgcagata cagtgatctt ggttgacctt tggtggaatc
    66721 ctgcggtgga agcgcaagcc attggccgtg cccatcggat gggtcaggaa gaaacggttg
    66781 aggtctatcg cttggtgacc aagggaacca ttgaagaaaa aattcaggaa ctccaagaac
    66841 aaaagaaaca tctggtgtca caagtattgg atggtacaga gtcacgtggt agtctgaccc
    66901 tagcagaaat tagagaaatt ttgggaattt ctgaagccag cacttgaaaa atcaagacaa
    66961 tacgctataa tgaagtgttg aaaggaaata gaaaatgaaa caagaacgat ttccattggt
    67021 gtcagatgac gaggtcatgt tgactgaaat gccagtcatg aatctctatg atgagtctga
    67081 tctgatcagt aatatcaagg gtgagtatcg agataaaaat tatttagaat gggctcctat
    67141 tactgaagaa aaactagtaa aaccgattga aaagcaagtc gaaaaaccta aaaaggctcc
    67201 tttaggggtt aaaaaagaag gaaagagcta tgcggaggtg gcgcgtgaag aagcgcgtgc
    67261 ggacttgaaa aagaaacgct ctgctaacta cctaactcag gatttcagcc ttgcgagacg
    67321 tcattctcag cccagtctag ttagacaggg caatcaaccg acaactcctt tccaaaagga
    67381 aaatcctggt gaatttgtca aatatagcca aaaattgacc cagtctcatt atatcttggc
    67441 ggaagaagtt cattctatcc ctaccaagaa tgaagaagtg tcagcacctg ctccaaagaa
    67501 aaacaattat gattttctaa agaagagcca aatctacaat aaaaaaagta aacaaacaga
    67561 acaagaacgt cgggttgccc aagagttgaa tctgaccaga atgacagaat aggggagaaa
    67621 acatgtcaaa gacatatcat tttatcggaa ttaagggatc agggatgagt gccttggcct
    67681 tgatgttgca ccagatgggg cacaaggttc agggatcaga tgttgaaaag tactacttta
    67741 cccaacgcgg tcttgagcag gcaggaatta ccattcttcc ttttgatgaa aagaatctag
    67801 acggtgatat ggaaattatc gctggaaatg cctttcgtcc agataacaac gtcgaaattg
    67861 cctatgcgga ccaaaatggt atcagctaca aacgttacca tgagtttcta ggtagcttta
    67921 tgcgtgactt tgttagcatg ggagtagcag gagcacatgg aaaaacttca acgacaggta
    67981 tgttgtctca tgtcttgtct cacattacag ataccagctt cttgattgga gatgggacag
    68041 gtcgtggttc ggctaatgcc aaatattttg tctttgaatc tgacgaatat gagcgtcact
    68101 tcatgcctta ccacccagaa tactctatta tcaccaacat tgactttgac catccagatt
    68161 atttcacaag tctcgaggat gttttcaatg cctttaacga ctatgccaaa caaattacca
    68221 agggtctttt tgtctatggt gaagatgctg aattgcgtaa gattacgtct gatgcaccaa
    68281 tttattatta tggttttgaa gctgaaggca atgactttgt agctagtgat cttcttcgtt
    68341 caacaactgg ttcaaccttc accgttcatt tccgtggaca aaacttgggg caattccaca
    68401 ttccaacctt tggtcgtcac aatatcatga atgcgacagc cgttattggt cttctttaca
    68461 cagcaggatt tgatttgaac ttggtgcgtg agcacttgaa aacatttgcc ggtgttaaac
    68521 gtcgtttcac tgagaaaatt gtcaatgata cagtgattat tgatgacttt gcccatcatc
    68581 caacagaaat tattgcgacc ttggatgcgg ctcgtcagaa atacccaagc aaggaaattg
    68641 tagcagtctt tcaaccgcat acctttacaa gaaccattgc cttgttggac gactttgccc
    68701 atgctttaaa ccaagcagat gctgtttatc tagcgcaaat ttatggctcg gctcgtgaag
    68761 tagatcatgg tgacgttaag gtagaagacc tagccaacaa aatcaacaaa aaacaccaag
    68821 tgattactgt tgaaaatgtt tctccgctcc tagaccatga caatgctgtt tacgtcttta
    68881 tgggagcagg agacatccaa acctatgaat actcatttga gcgtctcttg tctaacttga
    68941 caagcaatgt tcaataggat gttcccatgg aaattccaat taagattatt caggcaagca
    69001 agtctgattt gcctgagata ggggcacttc agacctcgtc ttttccagct gaaaagcagc
    69061 aactttccca tattttagaa gaaagtatcc gtaagtgtgc ggataccttt cttctagcta
    69121 gggatgaaaa tcaactttta ggctatattt tatcaagtcc ccagtcagac aatccgcaat
    69181 gtctaaaagt acattcttta gtcatcgagt ctgaccatca gagacagggc ctgggaacac
    69241 ttcttcttgc agccttgaaa gaggtggcag ttgagctgga ttacaaagtg attcgtttgg
    69301 agagtcctga tgagctgctt tcctattttg gaatgaacgg ttttgttgat gaagaagaaa
    69361 ctttgctcta tgcaactagc cagggctata gtatgatttg gtttaatccc ttttatctgg
    69421 aggaacaatg aaaatcagac aagcaagatt agaagatttg gatcggattg ttgaacttga
    69481 atttgaaaat ttttcggtcg aagaagccat tcctccttct gtctttgaag cacatttgag
    69541 agaaattcag acctcttttc tggttgctga aaaagaagga agaatcatgg gttatatcga
    69601 aggaccagtt gacctgcacc gccatctgca agaccagtct tttacagaag aaataaaaga
    69661 ctatagtcat gagcctggtg gttatatctc tgtgacctgt ctgtctattg ccaaggaggc
    69721 acagggactc ggactgggtc agaaattgct gacagccttg aaagaagttg ctcttgaaga
    69781 tgagagagat ggcattaatc taacctgtca tgactatctc atcgcctatt atgaaaaaca
    69841 tggatttgtc aacgaaggcc agtcccagtc aacctttgca ggggaaacat ggtatgatat
    69901 ggtctgggaa atgaaaaaat aagttaggaa aagtatcata gattgctttt tttggacttt
    69961 taagatataa tattatggat tatcaacaag gaggaaaaac ttttgagtga aaagtcaaga
    70021 gaagaagaga aattaagctt taaagagcag attctgagag atttagaaaa agtaaaaggc
    70081 tatgatgaag ttctgaaaga agatgaggca gtagttcgca ctcctgcaaa tgaaccttca
    70141 gctgaagaac tcatggctga ttccttgtca acggtagagg agattatgag aaaagctcct
    70201 accgtgccta ctcacccaag tcaaggtgta ccagcttctc cagcagatga gattcaaaga
    70261 gaaactcctg gtgttccaag tcatccaagt caagatgtac cttcttctcc agcggaagaa
    70321 agtggatcaa gaccaggtcc aggtcctgtt agacctaaga aacttgaaag agaatacaat
    70381 gaaaccccaa caagggtagc tgtttcctat acgacggcag agaaaaaagc agaacaagca
    70441 ggtccagaaa cacctacgcc tgctacagaa acagtggata tcatcagaga tacatcacgt
    70501 cgtagccgta gagaaggagc aaaacccgct aagcctaaga aagagaagaa gtcacatgtg
    70561 aaagcttttg tgatttcatt ccttgtattc cttgccttgc tctcagcagg tggttacttt
    70621 ggttaccagt acgtgctaga ttccttatta cctatcgatg ctaattctaa gaaatatgtg
    70681 acggttggaa ttccagaagg ttcaaacgtt caagaaatcg gtacgacgct tgaaaaagct
    70741 ggtttggtaa agcatggtct gatttttagt ttttatgcca agtataaaaa ttataccgac
    70801 ttgaaagcag gttactacaa tttgcaaaag agtatgagta cagaagactt actcaaagag
    70861 ttgcaaaaag gtggaacaga tgaaccgcaa gaacctgtac ttgcgacttt gacaattcca
    70921 gaaggttata ccttggatca gattgctcaa gctgtgggtc aattgcaagg tgacttcaaa
    70981 gagtctttga cagcggagac tttcttggct aaagttcaag atgagacgtt tatcagtcaa
    71041 gcagtagcga aatatcctac tttactggaa agtttgcctg taaaagacag cggtgcgcgt
    71101 tatcgtttgg aaggatacct tttcccagct acatactcta tcaaggaaag cacaactatt
    71161 gagagcttga ttgatgagat gttagctgct atggataaga acctatctcc ttactatagt
    71221 actatcaaat ctaaaaactt gactgtcaat gagttgttga ccattgcttc cttggtcgaa
    71281 aaagaaggtg ccaagacaga agatcgtaag ctcattgcag gtgtattcta caatcgtttg
    71341 aatcgtgata tgccacttca aagtaatatt gcaatcttgt atgcccaagg aaaactgggg
    71401 caaaatatca gtctagctga ggatgttgcg attgatacca acattgattc accttataat
    71461 gtttataaaa atgtaggtct catgcctggt ccagtcgata gtccaagtct ggatgcgatt
    71521 gagtcaagca tcaatcaaac taagagcgat aacctctact ttgtagcaga tgtcacagaa
    71581 ggcaaggtct actatgctaa caatcaagaa gaccacgacc gcaatgtcgc tgaacatgta
    71641 aacagcaaat taaactaaac aaactaaaat tatgtgatat ttcacataat tttctttaga
    71701 aaatattatc agaagaaagt tgagaaaaat ggcagaaaaa acatatccta tgacccttga
    71761 ggaaaaggag aaacttgaaa aagaattaga agaattgaaa ttggttcgtc gaccagaagt
    71821 ggtagaacgc attaagattg cccgttcata cggtgatctt tcagaaaaca gtgagtacga
    71881 agcagctaag gatgaacaag cctttgtcga aggacaaatc tctagcttag aaacaaaaat
    71941 ccgctatgct gaaatcgtca atagcgacgc agttgcccag gacgaagtag cgattggtaa
    72001 aacagtcacc atccaagaaa ttggcgagga cgaagaagaa gtttatatta tcgtaggttc
    72061 agctggtgcg gatgcctttg caggtaaggt ttcaaatgaa agcccaattg ggcaggcctt
    72121 gattggcaag aaaacaggtg acacagcaac aattgaaacg cctgttggta gctatgatgt
    72181 aaaaatcttg aaggttgaaa aaacagccta aaaacagaaa aaggagtggg gaggcgatgt
    72241 gcttcactca ctcctttttc cattttgcta ttcttcgaaa atctcttcaa accacgtcag
    72301 cgtcgccttg ccgtatatat ggttactgac tttgtcagtt tcatctacaa cctcaaaaca
    72361 gtgttttgag ctaacttcgt cagtttcatc tacaacctca aaaccatgtt ttgagccgac
    72421 ttcgtcagtt tcatctacaa cctcaaaacc atgctttgag ctgacttcgt cagtttcatc
    72481 tacaacctca aaaccatgtt ttgagctgac ttcgtcagtt tcatctacaa cctcaaaacc
    72541 atgttttgag ctgacttcgt cagttctatc tacaacctca aaacagtgtt ttgagcaacc
    72601 tgcggctagt ttcctagttt gctctttgat tttcattgag tattagatgt atagtgcatt
    72661 gaagttaaaa tagtaaactt tgatttctaa gacattatta gaaattagat taaattcctt
    72721 aatcgatttg cgcatgtttt atttcatttc attatacttt agattggaaa ataaggaatc
    72781 acataaatcg caagaaatag ggaatctgat tcgtgtttat aaccgttcaa aaagggaaga
    72841 ggctgaaagt gagccactta atctttatgt cgaagatgaa aagggcaatc tccttgcggg
    72901 tttgatagca gagacttttg gaaattggct agaaatcgag tatttgtttg taaaagagga
    72961 actgcgaggg caaggaatcg gttcaaaact attgcaacag gcagaaagtg aagctaagaa
    73021 tcgaaattgt tgttttgcct ttgtcaatac ttatcagttc caggcaccgg acttttatca
    73081 gaaacatggc tacaaggaag ttttttcttt gcaagactat ctctacatta ggcaaagata
    73141 ttattaccaa aagaatctgt aaggtgagta tggaggtata atacaaagag aggctcgcac
    73201 ataagtatgg aggtgtactg atgtatatga gtaactatcg ataaatacca gttataacct
    73261 agaaattgtg tctttctaga cgatattgag gacaatataa tcgtagctcc aaaattagga
    73321 atcaaggctt atcaggttaa gaaaagaagt gatgttgttg atattttaaa acaatttatt
    73381 taaactaaaa actctctatc tttttaaatt gacattaatc cgagattccc ctctaggatt
    73441 ttgtgttgct ttcattaaat ttacaggtaa gacttgctag cttcagtaaa tatacacaag
    73501 tttttcagaa tagagtgaaa tccgaaagaa aatggaaata atgaaaactc ttgtaggcat
    73561 aagaaaacac ctctgtgtta tacttgttgt tcaaccacaa acacaagaaa ggcacagaaa
    73621 tgcaagacaa ttatactaca aaagccaaac atttgacaat cgatagccgt cgcttaatcg
    73681 aaagatggaa aaaagaaggg aaatcaaata gagaaattgc ctctctactt ggaaaagctc
    73741 ctcaaactat ccacactgaa atcaagcgtg ggacagtccg acaatgtctt ggaaaagggc
    73801 gcttcaaaga ggtttattct gccgactatg ctcaacagtc ttatgaaaac aatcgcaagc
    73861 gctcggtcaa gaaatcaagc gtgaccaagg aactaaagga aaagattctc cactatcata
    73921 accaaaaatt ttcgcctgaa atgatggtga tggctaaagg ggttaacgtg ggaatttcaa
    73981 ccatttacta ttggattcat catggaaaat tggggttaag caaacaggat ctgctttacc
    74041 ctagaaaagg aaaagcgctt aagaaacagg ctagcaccaa ctttaaacct gctggtcaat
    74101 ccatcgaaca gcggtctgaa gctatcaatc ttcgcttgga gaatgggcat tatgagattg
    74161 atacggttct acttacgaga gcgaaaaact actgcttgct tgtcttgacg gatcgaaaga
    74221 gtagacatca gatcatccga ttgattccaa ataaaagtgc tgaggtggtc aatcaggctc
    74281 taaaactcat cttaaaacaa cacaagattc tttccatcac ggcagataat ggaacggaat
    74341 tcaatcgctt gtttgatgta ttttctgagg agcacattta ttatgcgcac ccctatgcct
    74401 tttgggaaag gggaactaat gagaatcaca acaggttcat tcgtagatgg ttacctaagg
    74461 gaaccaagaa aatgactccc aaagaagtcg cattcatcga aaagtggatt aacaactatc
    74521 ctaaaaaatg cttggactac aagtcaccca gagaagactt ctggatggct aacttgaact
    74581 tgaaatttag caaaatggaa ataattttta ttaaacgctt ccaatagcgg ttaaaagttg
    74641 acaaatttaa attttaggac tacactaagt aagtaaattt tattttaaag gagaatttgt
    74701 tatgaattta acatttttag gcttatgtat tgcctgtatg ggcgtatctg tcggtgaagg
    74761 tttattgatg aatggactgt ttaaatcagt agcacgccaa ccagatatgc tttctgagtt
    74821 tcgtagtttg atgtttttag gtgttgcctt tattgaagga actttctttg taactcttgt
    74881 cttctcattt attatcaaat aaatacatgg aacgagaaga aaagggagga ttttagatgg
    74941 aagaaagtat taatccaatc atctctattg gtcctgttat cttcaatctg actatgttag
    75001 ccatgacttt gttgattgtg ggagttattt ttgtctttat ttattgggca agccgcaata
    75061 tgaccttgaa acccaaagga aagcaaaatg tacttgagta tgtctatgac tttgttattg
    75121 gatttacaga acctaacatt ggttcgcgct acatgaaaga ttactcactc tttttccttt
    75181 gtttattcct tttcatggtg attgccaata accttggctt aatgacaaag cttcaaacga
    75241 tcgatgggac taactggtgg agttcgccaa ccgctaattt accgtatgac ttaaccttat
    75301 cttttcttgt cattttgttg acacatatag aaagcgttcg tcgtcgtgga tttaaaaaaa
    75361 gtataaaatc ttttatgagt cctgtttttg tcataccgat gaatatcttg gaagaattta
    75421 caaacttctt atctttggct ttgcggattt ttgggaatat ctttgcagga gaggtcatga
    75481 cgagtttgtt acttcttctt tcccaccaag ctatttattg gtatccagta gcctttggag
    75541 ctaatttggc ttggactgca ttttctgtct ttatttcctg catccaagct tatgttttta
    75601 ctcttttgac atctgtgtat ttagggaata agattaatat tgaagaggaa tagaaaggag
    75661 taactgatgc acgtaacagt aggtgaatta attggtaatt ttattttaat cactggctct
    75721 tttattcttt tgctagtctt gattaaaaaa tttgcatggt ctaatattac aggcattttc
    75781 gaagaaagag ctgaaaaaat tgcttcagat attgacagag ctgaagaagc ccgtcaaaaa
    75841 gcagaagtat tggctcaaaa acgcgaagat gaattggctg gtagccgtaa agaagctaag
    75901 acaatcattg aaaatgcaaa ggaaacagct gagcaaagta aggctaatat cttagcagat
    75961 gctaaactag aagcaggaca cttaaaagaa aaagccaatc aagaaattgc tcaaaataaa
    76021 gtagaagctt tacagagtgt taagggtgag gtcgcagatt tgaccatcag cttagctggt
    76081 aaaatcatct cacaaaacct tgacagtcat gcccataaag cactcattga tcagtatatc
    76141 gatcagctag gagaagctta atggacaaga aaacagtaaa ggtaattgaa aaatacagca
    76201 tgccttttgt ccaattggta cttgaaaaag gagaagaaga ccgtatcttt tcagacttga
    76261 ctcaaatcaa gcaagttgtt gaaaaaacag gtctgccttc ttttttaaaa caagtggcag
    76321 tagacgagtc ggataaggaa aaaacaattg cttttttcca agattctgtg tcgcctttat
    76381 tacaaaactt tatccaggtt ctggcctaca atcacagagc aaatcttttt tatgatgtgc
    76441 ttgtagattg cttgaaccga cttgaaaaag aaacaaatcg atttgaagtg acgattacgt
    76501 ctgctcatcc tctaactgat gaacagaaga ctcgtttgct ccctttgatt gagaaaaaaa
    76561 tgtctctgaa agtaaggagt gtaaaagaac aaatcgatga aagtctcatt ggtggttttg
    76621 tcatttttgc caatcacaag acaattgatg tgagtattaa acaacaactt aaagttgtta
    76681 aagaaaattt gaaatagaaa gtggtgttct tttggcaatt aacgcacaag aaatcagcgc
    76741 tttaattaag caacaaattg aaaatttcaa acccaatttt gatgtgactg aaacaggtgt
    76801 tgtaacctat atcggggacg gtatcgcgcg tgctcatggc cttgaaaatg tcatgagtgg
    76861 agagttgttg aattttgaaa acggctctta tggtatggct caaaacttgg agtcaacaga
    76921 cgttggtatt atcatcctag gtgactttac agatatccgt gaaggcgata caatccgccg
    76981 tacagggaaa atcatggaag tccctgtagg tgaaagtctg attggtcgtg ttgtggatcc
    77041 gcttggtcgt ccagttgacg gtcttggaga aatccacact gataaaactc gtccagtaga
    77101 agcaccagct cctggtgtta tgcaacgtaa gtctgtttca gaaccattgc aaactggttt
    77161 gaaagctatt gacgcccttg taccgattgg tcgtggtcaa cgtgagttga ttatcggtga
    77221 ccgtcagaca gggaaaacaa ccattgcgat tgatacaatc ttgaaccaaa aagatcaaga
    77281 tatgatctgt atctacgtcg cgattggaca aaaagaatca acagttcgta cgcaagtaga
    77341 aacacttcgt cagtacggtg ccttggacta cacaatcgtt gtgacagcct ctgcttcaca
    77401 accatctcca ttgctcttcc tagctcctta tactggggtt gctatggcgg aagaatttat
    77461 gtatcaaggt aagcatgttt tgattgtata cgatgatcta tcaaaacaag cggtagctta
    77521 tcgtgaacta tcgctcttgc ttcgtcgtcc tccaggtcgt gaagccttcc caggggatgt
    77581 tttctatctc cacagccgtt tgcttgagcg ctcagctaaa gtttctgatg aacttggtgg
    77641 tggatcaatt acagccctac catttatcga gacacaagca ggagatatct cagcctatat
    77701 cgcaaccaac gtgatttcta tcactgatgg acaaatcttc cttggcgatg gcctcttcaa
    77761 tgcaggtatt cgtccagcca tcgatgcggg ttcatctgta tctcgtgtag gtggttctgc
    77821 acaaatcaaa gccatgaaga aggttgctgg tacacttcgt atcgaccttg cttcataccg
    77881 tgagttggaa gcctttacta agtttggttc tgacttggac gcagcaacac aggctaagtt
    77941 gaaccgtgga cgtcgtaccg ttgaggtctt gaaacaacct gttcacaaac cattacctgt
    78001 tgagaaacaa gtaaccattc tttatgcttt gacacatggt ttcttggata ctgttccagt
    78061 agatgatatt gttcgtttcg aggaagagtt ccataccttc tttgatgctc aacatccaga
    78121 gattttggaa accattcgtg atacaaaaga cttgccagaa gaagcagtct tggatgctgc
    78181 gattacagag tttctcaatc aatctagctt ccaataagaa tagaggtgtc agatggcagt
    78241 atctctaaat gatattaaaa caaaaatcgc ctcaacaaaa aatacgagtc aaatcactaa
    78301 tgccatgcaa atggtatcgg ctgctaagct aggtcgttct gaagaagctg ctcgcaactt
    78361 ccaagtttac gctcagaaag tgcgtaaact tttgacagat atccttcatg gtaatggagc
    78421 tggtgcttca actaatccga tgttgattag ccgttctgtg aagaagacag gctatatcgt
    78481 tatcacttca gaccgcggtt tggttggagg ttataattcc tctattttga aagctgttat
    78541 ggagttgaaa gaagaatacc acccagacgg taaaggtttt gaaatgatct gtatcggtgg
    78601 gatgggagct gatttcttta aggctcgcgg tattcaacca ctttatgaat tacgtggctt
    78661 ggcagaccaa cctagctttg atcaagttcg taagattatt tcaaaaactg ttgaaatgta
    78721 ccaaaatgaa ctctttgatg agctttatgt ttgctacaac caccatgtca atacgctaac
    78781 cagtcaaatg cgtgtggaac aaatgcttcc gattgttgac ttggatccaa atgaagcgga
    78841 tgaagagtac agcttgactt ttgaattgga aaccagccga gaagaaattc tggagcagtt
    78901 gttgcctcag tttgcagaaa gtatgattta cggtgccatt atcgatgcca agacagctga
    78961 gaatgctgcg ggtatgacag ccatgcaaac agcgacagat aatgctaaga aagtcatcaa
    79021 tgatttgaca attcagtata accgtgccag acaggcggcg attacacaag aaattacaga
    79081 aatcgtagca ggtgctagtg ccttagaata ggctctagtc cagctcgtat gaaaatgaac
    79141 ttaggaccta gttgagctag gaaccgacag tatcttatat agaataggag aaggagatga
    79201 gttcaggtaa aattgctcag gttatcggtc ccgttgtaga cgttttgttt gcagcagggg
    79261 aaaaacttcc tgagattaac aatgcacttg tcgtctacaa aaatgacgaa agaaaaacaa
    79321 aaatcgtcct tgaagtagcc ttggagttag gagatggtat ggttcgtact atcgccatgg
    79381 aatcaacaga tgggttgact cgtggaatgg aagtattgga cacaggtcgt ccaatctctg
    79441 taccagtagg taaagaaact ttgggacgtg tcttcaacgt tttgggagat accattgatt
    79501 tggaagctcc ttttacagaa gacgcagagc gtcagccaat tcataaaaaa gctccaactt
    79561 ttgatgagtt gtctacctct tctgaaatcc ttgaaacagg gatcaaggtt attgaccttc
    79621 ttgcccctta ccttaaaggt ggtaaagttg gacttttcgg tggtgccgga gttggtaaaa
    79681 ccgtcttaat ccaagaattg attcacaaca ttgcccaaga gcacggtggt atttcagtat
    79741 ttactggtgt tggggaacgt actcgtgagg ggaatgacct ttactgggaa atgaaagaat
    79801 caggcgttat cgagaaaaca gccatggtct ttggtcagat gaatgagcca ccaggagcac
    79861 gtatgcgtgt tgcccttact ggtttgacaa tcgctgaata cttccgtgat gtggaaggcc
    79921 aagacgtgct tctctttatc gataatatct tccgtttcac tcaggctggt tcagaagtat
    79981 ctgccctttt gggtcgtatg ccatcagccg ttggttacca accaacactt gctacggaaa
    80041 tgggtcaatt gcaagaacgt atcacatcaa ccaagaaggg ttctgtaacc tctatccagg
    80101 ctatctatgt gccagcggat gactatactg acccagcgcc agcaacagcc ttcgctcact
    80161 tggattcaac aacaaacttg gaacgtaagt tggtacaatt gggtatctac ccagccgttg
    80221 acccacttgc ttcaagctca cgtgccttgg cacctgaaat cgttggagaa gagcactatg
    80281 cagttgctgc tgaagtaaaa cgtgtccttc aacgttacca tgaattgcaa gatatcattg
    80341 ctatccttgg tatggatgag ctttctgatg aagaaaagac cttggttgct cgcgcccgtc
    80401 gtatccagtt cttcttgtca caaaacttca acgttgcgga acaatttact ggtcagccag
    80461 gttcttatgt tccagttgct gaaactgtac gtggctttaa ggaaatcctt gatggtaaat
    80521 acgaccactt gccagaagat gccttccgtg gtgtaggttc tatcgaagat gtgattgcaa
    80581 aagctgaaaa aatgggattt taagaggtga tctatggctc agttaactgt ccagatcgtg
    80641 acaccagatg gtctcgtcta tgatcaccat gccagctatg tatcggttcg aactctggat
    80701 ggtgagatgg ggatcttgcc acgacatgaa aatatgattg cggttttagc agttgatgaa
    80761 gtaaaggtaa aacgtatcga tgataaagat cacgtgaact ggattgcagt aaacggtggc
    80821 gttattgaaa ttgctaatga tatgatcaca atcgtcgctg actctgcaga acgtgctcgt
    80881 gatatcgata tcagtcgtgc agaacgtgcc aaacttcgtg cagaacgtgc aattgaagaa
    80941 gcacaagaca aacatttgat tgaccaagaa cgtcgtgcta agattgcttt gcaacgtgct
    81001 attaaccgta ttaatgtcgg aaatagacta taagaaaaaa tgaacttgaa aataccaagt
    81061 tcatttttta tggtgtttta aggagcaaaa cggatgcaga ctgcttcggg aacatggaag
    81121 tcgttggaga gttctgctag acgaccattg tcacaattac gtttaaagac agttgcattg
    81181 tcagagtctt gatggacaac aatgagaaat ttttggtcgg gtgtcaaatc aaaatcacgt
    81241 ggagtctgac catgcgttgg aacgatttct aataactcta agctaccgtc cgcaaggatg
    81301 gtatatactg cgatagaatc atggccacgg ttagaagcgt agaggtattt accgtcttta
    81361 gagagatgaa tagcagcggt tccattaaag ccttcgtaag cttccggtaa agttgaaatg
    81421 acctgcatac gttcaaattc gccaacgcca tcgtagatta aaacttcgat agtactattg
    81481 agttcacaaa tgagataagc gattttatag tggttatgga aaatgatatg gcgtgagcct
    81541 gctcctggct tgctgtgata ggtatagagc ttagataatt ttccttcttg atcgaggtca
    81601 taggtgatga cttggtcagt tcccaagtcg caggtcacta gatagtggtc aggtgttaaa
    81661 tctgtatagt gaacatgggg ggaagcttga ttttcatgtg gaccttggcc actgtgttga
    81721 tccatatcac taagtagaag actaccatct tcctggcgtt tataaacaag gacttgtccc
    81781 ttgtgatagt tagctgcgta aaccaaatca cgcttttcat cgacagcaac ataacagtgg
    81841 ggagctcctt cttcaacaac atgatttaac acagtcccgt cagtttgata ggctgcaatt
    81901 ccccccttat cgtcttggct accaacagtg tataaatgtt ggtgctggtc aaaggcaagg
    81961 taggttggac ttggctcagc tgcaaaaagt tctagatttg aaagctgacc agtttctgta
    82021 tcaaagtctg ccttgtaaat cccttgagaa gtacgacgtg tataagttcc aaaataaaca
    82081 gtttctttca ttactatacc tctgtgtaaa gataagacta ttatatcaca aaaacaagta
    82141 aattaaagat atccaattag atgtaagcac tttaaaaaag agttattttg tttcaaaaat
    82201 ggtataatga gagaacaata gaaaggaagt atttatggag caaaaagaga aacattttag
    82261 cctatcttgg tttttcaagt ggtttttaga taacaaggca attacggtat ttttagtaac
    82321 cttattattg ggactgaatc tttttatttt aagtaagatt agttttctat tttcacctgt
    82381 tttagacttt ttagcagttg tgatgttgcc agtcattttg tctggtttgt tatattattt
    82441 gttgaatcct attgttgatt ggatggagaa gcataaggtt aatcgtgtta tagctatcac
    82501 tattgtcttt gttatcatcg ctctctttat catttggggc ttggcagtcg ccattccaaa
    82561 tctgcaacgt caggttttga cctttgcaag aaacgttcct gtttacttag aagatataga
    82621 taggattgtt aatggattgg tagcccagca tctgccagat gatttcagac ctcaattaga
    82681 gcaagttttg accaattttt ctagccaggc tacagttttg gcaagtaagg tttcatctca
    82741 ggcagtcaac tgggtgagtg cctttattag cggggcttct caagtgattg ttgccttgat
    82801 tatcgttcct ttcatgctct tttatctctt gcgtgatggg aaaggcttgc gtaactattt
    82861 gacccaattc attccaagaa aattgaagga acctgttgga caagttctat cagatgtgaa
    82921 tcaacagttg tccaactatg ttcgagggca agtgacagtg gctattattg tagcagtaat
    82981 gtttatcatc ttcttcaaga ttattggtct acgctatgcg gttacgctgg gggttactgc
    83041 tggtatttta aatctggttc cttatcttgg tagctttcta gccatgcttc ctgctctagt
    83101 attgggtttg attgctggtc cagtcatgct tttgaaagta gtgattgtct ttatcgtaga
    83161 acaaactatt gaaggccgtt ttgtctctcc attgattttg ggaagtcaat taaacatcca
    83221 ccctattaat gttctctttg ttttgttaac ttcaggatct atgtttggta tctggggagt
    83281 tttacttggt attccggttt atgcctctgc taaggttgtc atttcagcca ttttcgaatg
    83341 gtataaggta gtcagtggtc tatatgaatt agagggtgag gaagtcaaga gtgaacaata
    83401 gtcaacagat gttacaggct ttggaggagc aagatttaac taaggctgag cattatttcg
    83461 ccaaagcttt agaaaatgat tcaagtgatc ttctgtatga gttggcaact tatcttgaag
    83521 ggattggttt ctatcctcag gccaaggaaa tttacctgaa aattgtagag gattttccag
    83581 aggttcatct taatctagct gcaattgcta gcgaggatgg tcaaatagaa gaagccttta
    83641 cctatcttga ggaaatccaa gctgacagtg actggtatgt ctcgtctttg gctctgaagg
    83701 cagaccttta ccagctggaa ggtttgacag atgtggcacg tgagaaatta ttggaggcct
    83761 tgacctactc agaggattct ctcttgatat tgggtttggc agagttggat agtgagttgg
    83821 aaaattacca agcggctatt caagcctatg cccagttaga taatcgctcg atttatgagc
    83881 aaacgggcat ttccacctat caacgaattg gctttgccta tgctcagtta gggaaatttg
    83941 aaacggctac tgagttttta gaaaaagccc tggagttaga atacgatgac ttaacagctt
    84001 ttgagttggc cagtctttat tttgatcaag aagaatatca aaaagccacc ctctacttta
    84061 agcagcttga taccatttct cctgactttg aaggctatga gtatgggtac agtcaggctt
    84121 tacataagga acatcaagtt caagaagccc tgcgtatcgc taagcaagga ttagagaaaa
    84181 atccctttga aactcgcctc ttgctagctg cttcacaatt ttcttatgaa ttgcatgatg
    84241 ctagtggtgc agaaaattat ctccttactg caaaagaaga cgctgaggat acagaagaaa
    84301 tcttgcttcg tttagccact atttatctgg agcaggagcg ttatgaggat attctagact
    84361 tgcagagtga ggagccagaa aatcttttga ccaagtggat gattgctcgt tcttatcaag
    84421 aaatggacga tttggatact gcttatgagc attatcaaga gttgacagga gatttgaagg
    84481 acaatccaga atttctggaa cactatatct atctcttgcg tgaattggga cattttgaag
    84541 aagcaaaagt ccatgctcac acttacttaa aactggttcc agatgatgtg caaatgcaag
    84601 aactgtttga gagattgtaa gaatgtttaa acatatagaa ctgtagttta tctcttttga
    84661 tagctacggt ttttatttgt atatggtaga atctttttac aaaaatactt ggtaatcttg
    84721 tttattcatg ctataatagg aacaattact tttaggaggt gcagtatgtc ttatttattt
    84781 gagatattac cgagtttact gaatggtgcg agcacgactg tacaggtctt tgcactggtc
    84841 ttgctatttt cgattccctt gggcgttttg attgcctttg ccttgcaagt ccattggaag
    84901 cccctccatt atctgattaa catttacatc tgggttatgc gaggaacccc cttactcttg
    84961 caactgattt ttatctatta tgtgctccca agtattggga ttcgtttaga ccgccttcct
    85021 gcagctatta ttgcctttgt tctcaactat gcagcttact ttgcagaaat tttccgtggg
    85081 ggaattgaca ctattccaag aggacagtat gaggctgcca aggtcttgaa gtttagccct
    85141 tttgacagag tgcgctatat tatcttgccc caagtgacca agatcgttct tcctagtgtc
    85201 tttaatgaag ttatgagttt ggtcaaggat acttctttgg tctatgctct cggaatttca
    85261 gaccttatct tggctagtcg aacagctgct aaccgcgatg ctagtctggt tcctatgttc
    85321 ttggcaggag ccatttactt gattttaatt gggattgtga caattatttc caaaaaagtt
    85381 gagaaaaagt acagttatta tagatagggg gcagctatgt tagaattacg aaatatcaat
    85441 aaagtctttg gagacaaaca aatcctgtct gatttcagtc taagtattcc tgaaaagcaa
    85501 atcctggcta tcgttggacc ttctggtgga ggtaagacaa ctcttttacg tatgcttgca
    85561 ggtcttgaaa ccattgattc agggcaaatc ttttataatg gacaaccttt agagctagat
    85621 gaattgcaga agcgcaacct actgggattt gtcttccaag attttcaact atttcctcat
    85681 ctatcagttc tggaaaattt gactttatcg cctgtgaaga ccatgggaat gaagcaggaa
    85741 gaggctgaga agaaggcgag tggactcttg gaacagttag gactaggagg acacgcagag
    85801 gcctatcctt tctcactatc tggtgggcaa aagcagcggg tggctttggc gcgtgctatg
    85861 atgattgacc cagaaatcat tggctacgat gaaccaactt ctgccctgga tccagaatta
    85921 cgtttggaag tggagaagct aatcttgcaa aatagggaac ttgggatgac ccagattgtg
    85981 gttacccatg atttgcagtt tgctgaaaat atcgcagatg tattattgaa agtagaacct
    86041 aaataggagg aaaaatggat gaaaaaatgg atgcttgtat tagtcagtct gatgactgct
    86101 ttgttcttag tagcttgtgg gaaaaattct agcgaaacta gtggagataa ttggtcaaag
    86161 taccagtcta acaagtctat tactattgga tttgatagta cttttgttcc aatgggattt
    86221 gctcagaaag atggttctta tgcaggattt gatattgatt tagctacagc tgtttttgaa
    86281 aaatacggaa tcacggtaaa ttggcaaccg attgattggg atttgaaaga agctgaattg
    86341 acaaaaggaa cgattgatct gatttggaat ggctattccg ctacagacga acgccgtgaa
    86401 aaggtggctt tcagtaactc atatatgaag aatgagcagg tattggttac gaagaaatca
    86461 tctggtatca cgactgcaaa ggatatgact ggaaagacat taggagctca agctggttca
    86521 tctggttatg cggactttga agcaaatcca gaaattttga agaatattgt cgctaataag
    86581 gaagcgaatc aataccaaac ctttaatgaa gccttgattg atttgaaaaa cgatcgaatt
    86641 gatggtctat tgattgaccg tgtctatgca aactattatt tagaagcaga aggtgtttta
    86701 aacgattata atgtctttac agttggacta gaaacagaag cttttgcggt tggagcccgt
    86761 aaggaagata caaccttggt taagaagata aatgaagctt tttctagtct ttacaaggac
    86821 ggcaagttcc aagaaatcag ccaaaaatgg tttggagaag atgtagcaac caaagaagta
    86881 aaagaaggac agtaagataa aatagtggct gaaactgcgt tttgattagc aaaacgtagt
    86941 ttttttgtaa tctaggaaaa cgataatagc gattgaatat ggataattga atatggaata
    87001 gcccactgtg atttctaaaa cattgttaaa aattgatttg acttccaaaa ttaaaatgtt
    87061 ctgtaatgaa atgctgatgt aactgtttta ggaacaataa aacgcataat atcaaggttt
    87121 ttgcacctta cattatgcgt ttttgtgatt ttaagacttg ttagctgatt ttttacaatc
    87181 ctgcgaaatc tttgatttct tgtgctgaca ttgaagagtc gcaacggacg ttgatttgtc
    87241 catctgtaat atgaacaaaa cctggtacag ttgggattcc atagcgtgag cggaatgctt
    87301 gcaaatcatt gagttggctt ggttcttcac tattgatgaa gtaaatgtga gctttggttt
    87361 cagctacgac acctgacaat gtatctgcaa atttacggca gtaagggcaa gttttgcgac
    87421 cgataaagaa ggttgcagtt tcttttttat caagagcttc ttgcgcacgc acaactgtag
    87481 tgacttcaag gtctttgatg ttatctaaaa attgttccat gagattacct cgctttcatt
    87541 gataagtcta gtatgccata aagtttctaa aattgcttag atttgatacg aaaaaagatg
    87601 aggttggttg gtctcatctt ttataggtct ttattttaca aatgcattga tttctgcttc
    87661 gatgttagca atcttagctt gtgattcttc gttggtttcc cctacaactg caatgtagaa
    87721 cttgattttt ggttctgtac ctgaagggcg aacggcaatc catgaaccgt cagcaagtgt
    87781 gtatttcaac acatcacttg gaggagttgt caagtttgta acagtaccgt cagcaacagt
    87841 agcagtttgt gccttgaagt cttctacgac agtgatagct gtttcgttcc attcttttgg
    87901 agcattgttg cggaatttag ccataatcgc tttgatttgt tcagcaccat cgacacctga
    87961 aagagtaaca gagattgttt tttctgcgta gtagccatat tctttataga tttcttcgat
    88021 accgtcagca agtgtcaaac cacgagaacg gtagtaggca gcaagttcag caacgacaag
    88081 aacggcttgg atggcatctt tatcacgtac aaatggttta atcaagtaac cgaagctttc
    88141 ttcaaatccc atcatgtaag tgtggttgtg tttttcttcg aattcttgga ttttttcagc
    88201 gataaatttg aaacctgtca agacgttgaa catagttgcg ccgtagcttt cagcaatctt
    88261 cgttaccaag tcagttgaaa cgatagattt gcagagagcg gcattttcag gaagagttcc
    88321 agcgtttttg tgagcttcca agatgtattt agccatgata gcaccgattt ggttacctga
    88381 aaggttgagg tagctaccat ctttttgaag aacttcaaca ccaacacggt cagcgtctgg
    88441 gtcagttgcg acaagaacat ctgcaccaac ttgacgacca agttcttcag caagggcaaa
    88501 ggctgcttgg ctttctgggt ttggagatgt tacagttgag aagtctgggt cagcagttgc
    88561 ttgcgcttca acaacttgaa cagagtcaaa tcctgcttgg gcaagagcac gacgagccaa
    88621 catttcacca gtaccatgaa gtggtgtgta gacaatcttc atgtctttac caaattcttc
    88681 aatcaaggct gggttgatgt ttatgtcctt aacctcttta aggtattcta tgtcaacagc
    88741 ttcgccgata acttcaatca agccagaagc tttttcagtt tccacatcag caacttcaac
    88801 tgcaaatggg ttttcgattg cacggatata agtagtcaaa gcgtccgcat cgtgtggagg
    88861 catttgtcca ccgtcttcac cgtaaacctt gtaaccgtta aatggagcag ggttgtggct
    88921 ggctgtgacc atgatacctg cgaaacagtt gagatgacga actgcaaatg atagttctgg
    88981 agttggacga aggctttcaa atacgtaaga tttgatgccg tgtttagcaa gaactgccgc
    89041 agattcaaag gcaaactcag gtgagaagtg acggctatcg taggcaattg ctacaccgcg
    89101 ttctttctcg tttccacctt ttgactcaat caaacgagcc aatccttcag tagcttggcg
    89161 aacaacgtag atgttgatac ggtttgtacc agcaccaacc aagccacgca tacctgcagt
    89221 accaaattca agatttgtat agaaggcatc ttccttagtt ttttcgtcca tattttccaa
    89281 atcttgacga aggtagtcag gaagctccac aaaatcaacc catttctggt aattttcttg
    89341 gtaagacatt caaattctcc tttattttta aaacatttaa tcagtttgat tatatcattt
    89401 tttttagttt tagtaaaacc ttatctgctt cgaacatctc ttcaaaccag gtcagattga
    89461 attttggggt tatatgatgt tgaggttagg aaaaattcga tttcagtaaa aaaagtaagt
    89521 cttctaataa caaaacattg atatagttgc ttagttttaa acaagcatat tataataaag
    89581 ctatggcata tagtactgat tttaaacagc gagcattaga ttacatcaaa gaggggcaca
    89641 gccatgtcga ggcagccaag ttttttggtg ttggcgtcag aactctcttc acgtgggaaa
    89701 agaaagatgt gaacaaggac acatagagag gaaaaagcga gtcgtcaaaa accgaaagat
    89761 tcctttagag gaattgaaag cctttgtaga ggctcatcca gatgcttttt tacgggaaat
    89821 tgcggcacat tttgattgtg ctgttccttc agtatgggca gctttaaagc agattaaggt
    89881 cactttaaaa aaagatgacg agctttaagg aacaagagcc agagaaagtc gctgagtttc
    89941 ttgatatttt ggataaccta aaaaatttac caatcgtata tattgacgaa acaggaatcg
    90001 accgctacct ctatcgtcct tatgcagggg ctcctagagg ggagaaagtc tatgaaaaga
    90061 ttagcggacg tcgttttgag cgaacttcaa ttgttgcagg acaagtagac ggagagttta
    90121 tagctcccat gatttacaag aaaagcatga caagcgattt ctttgtggag tggttcaaaa
    90181 cgcaactcct acctgctttg aagacacctc atgttattgt catgggcaat gctagttttc
    90241 atcccaagaa cattttggat gaactctgca tccaagataa acactttttc ttacctctac
    90301 caccttattc accggatttg aatcctattg agcaagcttg ggctatcttg aaaaagaaag
    90361 tgacggattt attaagggaa gttccaacta tttttgaatg tttggaatgc ttttttaaaa
    90421 ctagatgact ataacggttc taaaggaacc tatcgagtag tcattaaaac taaggatact
    90481 gctggttaag agaagacggt atacgatcaa accattcacc gtgtagccga aatcgttcag
    90541 aatgaagact tgtataagaa aggtttgaat gttgaacttg cgcaccaaca aattaaggga
    90601 ttttttgaag cagaatttaa aaatcgtatt aatggagttc ttaatactaa aataaaaaat
    90661 agtacattaa atcgtgtaaa taaaaaaact atacaccaga gcaacaaaaa ctccatgatc
    90721 aatttgaagc agaagcaacg gaagatgcta aaaaacaagg cgatattgtg ttgaatgttg
    90781 accaggattt catgagcata tctaagtcta ataaaagtgg ttcagactgg aagaaaactt
    90841 tcacagtgag gacaaccaat aggttagcaa atgacttgaa taatgtcttg aaacaggctg
    90901 ataaagatac tcctaatacc ccaatttggc taaactcagc tgcttctaaa gctaaagatg
    90961 atgacagagc atataaacta ctgaagactc ttataccagg agaaaattac ctatcatgtt
    91021 aaggataatc agctagaagt agaaacagat aaatacacat atactgccgc tagaaatggt
    91081 agtaaggaag ttggtattca agagtcagat atagcagcaa ctctaagtgc cgatgaatat
    91141 aattctaatc gccaaacctt tgagagagaa tacaaataca aaagcaaatg cccttaataa
    91201 tggttgggct agatctggtt ctgaagagtt caaaaagttc tcccactttg taggggtaga
    91261 caaagggatt gtgcgaacga atgtactgac tggtaaaaaa ctatctgata agattaggaa
    91321 agaagtggac tctggagata gcaaactagg aaaaggcggc tatttctcta ctggggatgt
    91381 tctattagga aaagatgttg tttcttatac cgtacaagta ttttcagaga ataatgaaag
    91441 agtaggagta aacactcaaa gtcaccgtgt tcagtataat ctcccaattc tagctgactt
    91501 ttcagtcatc caagatattg tggaaccatc acgaaccgtt gttgaaaaaa tcattccaaa
    91561 actaaatatt cccgaagaag agaaaaagaa aaaaacctca gaattggcag aactaatctc
    91621 agaaaatgtg aaagtttgct atgttgatga acaagggcgt ttgctatcat tgaaaaatga
    91681 tactggaatt ggagaaaaag aaagtgacgg aacttacatt accaataaaa aacaactgat
    91741 tggtaccagc tataatgtca cagataaaaa actcagtagc atgactacta ctgacggaaa
    91801 atattatact tttaaagaag cagatacaaa ttctgcaagt ttaactggga atattgtaag
    91861 cgaaggtaga acagtgacct tagtttatag agaaagcgaa gcgccaacca ctgctacagt
    91921 aacagccaat tactataaag aaggtagcca agagaagttg gcagagtctg ttataaaagc
    91981 tgatttagcg ataggttctg agtataccac agaatcaaaa actattgaag ggaaaacaac
    92041 aactgaggac aaagaagacc gagttatcac aaggaaaaca acatacacct tggtagcaac
    92101 tcctgcaaat gcgtaccaga agacggtgca acagttgact attactaccg tgagaatgtt
    92161 gaggaaacag tggttcccaa aacagcaacc tctactgaga cgaagactat aacgcgtatc
    92221 attcattacg ttgataaagt tacgaaccaa aatgtaaaag aagatgttgt tcaacctgta
    92281 accttaagcc gtacaaaaac tgagaacaag gtcacgggag ttgtaaccta cggtgaatgg
    92341 acaacaggaa actgggacga ggttatatct ggtaagattg acaagtacaa agatccagat
    92401 attccaacag ttgaatcaca agaagttacg tcagactcta gtgataaaga aataacggta
    92461 aggtatgacc gtttatcaac accagataaa ccaactccag aaaaaccaga aattccaagt
    92521 cctcaggaac caggtactcc aggtgaaccg actccagaaa aaccaatccc acaaccaaat
    92581 ccagagcatc caagtgttcc gacaccaaac ccagaactac caaatcaaga gactccaata
    92641 ccagagccaa ctccagaacc aggtactcca aaaactgaaa ctccagtgaa tccagaccca
    92701 gaagttccga cttatgagac aggtaagaga gaggaattgc caaacacagg tacagaagct
    92761 aatgctacct tggctagtgc tggtatcatg accttgttag ctagtctagt attaggattc
    92821 ttcaagaaaa aagaagatga aaaataatag attttagaat ctaggaacca ggaaaagctc
    92881 acagatgtgg gcttttttcc tggttttgag aacgaggtct ttcgtgaaga ataaaaacgc
    92941 ttacaagtac gttgaactgg gaaactatga atcctatttt tttaaaaata tttccagaaa
    93001 tcagttgcta aatagggtaa aaattgataa aataaggaat atctaaaaaa ttttaaggag
    93061 aatctagcaa atggatttca catgggcact gaagtatgcc actgaatttt tgggaactgc
    93121 cattttgatc attcttggga atggtgcagt tgccaacgtt gaacttaaag gtacgaaagg
    93181 tcaccaaagt ggctggatcg tcatcgctgt tggttatggt atgggggtta tgatcccagc
    93241 cttgatgttt ggtaacgtat ctgggaatca catcaaccct gctttcactc tagggcttgc
    93301 agttagcggt cttttccctt gggcacaagt ggtaccttac attatcgcgc aagtcttggg
    93361 ggctatcttt ggccaagcct tagttgtggc aacataccgt ccattctact tgaaaactga
    93421 aaaaccaaat aacatcttgg gaactttctc aactatttca agtattgacc atggtacaaa
    93481 agaaagtcgc tatgcagcaa ctgtcaatgg tttgattaat gagtttgttg gttcatttgt
    93541 tttgttcttt gcagctcttg gtttgactaa aaacttcttt ggtgctgaag tgcttcaatt
    93601 catgaaacaa aaggcaatag aagcaggaca aacagttgat ttttctgact tggctattaa
    93661 agcacaggtg gctccacaca ctgcttcagg actttctgtg gctcacttgg cacttggatt
    93721 cctcgttatg gctttggtaa catcacttgg aggacctaca ggacctgcct tgaacccagc
    93781 ccgtgacttg ggaccacgtc tccttcatgc tttccttcca aaatcagttc ttggtgagca
    93841 taaaggcgat tcaaaatggt ggtattcttg ggtaccagta gtagcaccta tcgcagcagc
    93901 aattgcggca gtagctgtat tcaaattcct ttatctctaa gaaatagctc ctttaacatt
    93961 tgagtgagca ccatctataa gtaagagagg atcagactgg ttctctcttt ttgatttttt
    94021 agggaaatga aagaaactct aaacaaactc ctctccagca gtggtttaga agtctcagtg
    94081 ggctattcca gcttcaatgg gctatagtag gttgcagttg aaataataga cccttgtttc
    94141 taaaacattg ttagaaattg gtttgaattc tccaatcaaa ttgtgcagtt ttcattctac
    94201 tatatattat cggagatggg ttccctatct tgtaagtctg ctttatagtg ggttgaagtt
    94261 ggaatagtcc tcccttcttt ctcaaacatt gtgaggaatt gatttacctt cctcaacaaa
    94321 atgttcagtt tctatttcat tttgctataa aataagcgat taggggggct attcttcgac
    94381 ctacattgac tctgctgagt cctatgattg ttatcgtttt atctgcaatt ttatactcaa
    94441 tgaaaatcaa agggcaaact aagaagctag ccgcaggttg ttcaaaacac agttttgagg
    94501 ttgtatagta gattgaaact agaatagtac acctcaactt ctaaaacatt gttagaaatc
    94561 gatttgattg tcctgatcga tttgccctat tcttgtttca ttttactata taaaccagag
    94621 aatgtttaca ttttcagcaa gtgagtggat ggataatgct gaaaactcct tgaaggataa
    94681 gtctatttag tactttctat tagttagtta aatttttacc aagaataatt cacaaaaacg
    94741 ttgtaaaaca cttgcaattt agctgaaatt tgataaaata gtaaggaaag ttagactgta
    94801 ttgcctactg tctatctata aaatatattt tattggaggc ttttactcaa atggcaaaag
    94861 aaaaatacga tcgtagtaaa ccacacgtta acattggtac tatcggacac gttgaccacg
    94921 gtaaaactac cctaactgca gctatcacaa ctgttttggc acgtcgcttg ccttcatcag
    94981 ttaaccaacc taaagactat gcgtctatcg atgctgctcc agaagaacgc gaacgcggta
    95041 tcactatcaa cactgcgcac gttgagtacg aaactgaaaa acgtcactac gctcacatcg
    95101 acgctccagg acacgcggac tacgttaaaa acatgatcac tggtgctgct caaatggacg
    95161 gagctatcct tgtagtagct tcaactgacg gaccaatgcc acaaactcgt gagcacatcc
    95221 ttctttcacg tcaggttggt gttaaacacc ttatcgtctt catgaacaaa gttgacttgg
    95281 ttgacgacga agaattgctt gaattggttg aaatggaaat ccgtgaccta ttgtcagaat
    95341 acgacttccc aggtgacgat cttccagtta tccaaggttc agcacttaaa gctcttgaag
    95401 gtgactctaa atacgaagac atcgttatgg aattgatgaa cacagttgat gagtatatcc
    95461 cagaaccaga acgtgacact gacaaaccat tgcttcttcc agtcgaggac gtattctcaa
    95521 tcactggacg tggtacagtt gcttcaggac gtatcgaccg tggtatcgtt aaagtcaacg
    95581 acgaaatcga aatcgttggt atcaaagaag aaactcaaaa agcagttgtt actggtgttg
    95641 aaatgttccg taaacaactt gacgaaggtc ttgctggaga taacgtaggt gtccttcttc
    95701 gtggtgttca acgtgatgaa atcgaacgtg gacaagttat cgctaaacca ggttcaatca
    95761 acccacacac taaattcaaa ggtgaagtct acatccttac taaagaagaa ggtggacgtc
    95821 acactccatt cttcaacaac taccgtccac aattctactt ccgtactact gacgttacag
    95881 gttcaatcga acttccagca ggtactgaaa tggtaatgcc tggtgataac gtgacaatcg
    95941 acgttgagtt gattcaccca atcgccgtag aacaaggtac tacattctct atccgtgagg
    96001 gtggacgtac tgttggttca ggtatggtta cagaaatcga agcttaattc gatttagttc
    96061 ccagaagaac aattatttaa gtcagacact aaaagaatct tgcttggcaa ggttcttttt
    96121 ttagatattg aactaatact caatgaaaat caaagagcaa actataatat attgaaacta
    96181 gaatagtaca tatttacttc taaaacattg ttagaaatcg atttgactgt cctgatcgat
    96241 ttgtcttgtt cttatttcat tttactatag aaagttagct acagactgct caaaacactg
    96301 tttttaggtt gtagatagaa ctgacgaagt cagtaacatc tatacgacaa ggcgaagctg
    96361 acgcggtttg aagagatttt cgaagagtat aatactagac taaaatcaaa aagcattata
    96421 caatagtgat atgaaatcaa ctaaagaaga aatccaaacc atcaaaacac tttttaaaga
    96481 ctctcgtaca gctaaatatc ataaacgcct tcaaatcgtt ctatagtaaa acgaaacaag
    96541 aacagggcaa atcgatcagg acagtcaaat cgatttctaa caatgtttta gaagtagagg
    96601 tgtactattc tagtttcaat ttattatatt tcgtctgatg ggcaaatctt ataaagagat
    96661 tatagagctt ttagactgta atcaaacaac gatttagcaa aatgtaaaaa aatatgagga
    96721 gttcggactc gactctctcc ttcaagaaac acgtggtggt cgtaaccatg catatatgac
    96781 agttgaggaa aagaaagtct ttcttgcccg ccatttgaag gctgcagagg caggagaatt
    96841 tgttacaatt gatgccttat ttcaggctta taaaaaggag ttaggtcgtt cctacacacg
    96901 tgatgccttc tatcaattgt tgaagcgcca tggttggcga aatattacgc cacgtccaga
    96961 acatcctaag aaagcagacg ctcaaaccat tgtcgcgtct aaaaataaaa tctcaattca
    97021 agaagaaaag aaagcgattt aaaaccagta gacgttttcg taaggttcac ttgatgtccc
    97081 aagatgaggc tggtttcggt agaatcagta aactgggatc ttgttggtct ccaataggag
    97141 taggtccaca tgtccatagt cactatatac gagaatttcg ctattgttat ggagctgttg
    97201 atgcccatac aggcgaatca tttttcttaa tagctggtgg atgtaatact gagtggatga
    97261 acgtcttttt agaagagctt tcacaagctt atccagatga ttatctttta ttcgttatgg
    97321 acaatgctat atggcataaa tcaagtacct taaagattcc gactaatatt ggttttacct
    97381 ttattcctcc atacacacca gagatgaacc ccattgaaca agtgttgaaa gagattcgta
    97441 aacgtggatt taagaataaa gcctttcaaa ctttggaaga tgtcatgaat caacttcaag
    97501 atatcataca aggactggag aaggaggtga taaagcccat cgttaatcgg agatggacta
    97561 gaatgctttt tgaaagcaga tgagtataaa attgaattgc ttataaaaaa gctccataca
    97621 ctggatgtgt atagagcaat ggggctttat ttgatataga gttcttggtt ttttaggaca
    97681 atttctcgga tacttgcaaa ctttttaagt tttttgattt cttctgaatg agtgacgaga
    97741 gtgataacat atccttcctt gcccatacga ccagtacggc cagcacggtg tgtgtaggtt
    97801 tcgctatctc taggaatatc aaagtttacg acacattcta ggctatcgat atcaattcca
    97861 cgagccaaaa ggtcagttgc aagaagcagg gttagttggt tatctttaaa cttttctaag
    97921 atgatttttc taaatttaac attaacatca ctagcgaggg aaacagtcaa tatatcacga
    97981 tactgtagtt tttcctcggc attcccaagg tctgacaggc tattgaagaa gactagacca
    98041 cggaaatcct ctacatgagc cagttttcgt agcatatcca ctcgatgacg ttggtctacc
    98101 tgcatgtaga aatgctggat attgtccaat ttttggtcag agagatcaat agtgcgtgta
    98161 ttcggcacaa tcttttcttg gtcaaacttg gtcgtggcac tcatgtagac cagttggtgg
    98221 tcacgaggtg cgtagtgagt gattttttct acaaagtgaa tctgagaatc atctagtaat
    98281 tggtcaaatt catccaggat gatggtttcc acattcatca tcttgatttt tttaagttta
    98341 atgagttcaa agatacggcc aggagttcca atcagaattt ctggcccctt tttaaggcgt
    98401 tcaatttgtc gtttctgact tgaacctgaa aggaagagtt gagcagtcaa tccgatagct
    98461 tctgcccacg ttttacatac atcaaaaatc tgtccagcaa gttccgtatt tggtgctaga
    98521 atcaagagtt gttgggcttt tttcttttgt agtctgagaa gacttggtag gagatacgct
    98581 agggtcttac cagttccggt ttggctcact cctaggaggt tttctccagc aagaaggggc
    98641 tcaaatagtt gagtttgaat gggggtgaat tcttggaaac cgagttggtc actcagttct
    98701 tgccattcag tcggtagttt ggttttcatt tttctgcctc aaatctaatg ccagcagtct
    98761 ggcgcatggt atatagtagc tcatgaacag atcctgcatc atacagccaa gtttggtaga
    98821 gattcagatc tggttgctgg atcatgtgtg caaatgcagc gacttcctca gtcatcgtat
    98881 gaggagcctg ttggatagga agctggactt gatttccttg gtggtcggta aaaatagctg
    98941 agcgaatatg ctcaatcgtg ttgagagtca aggttccatc tgttgtataa atctcgcaag
    99001 gaagattgga agtgatgttt tttccagcct tgatgtgaac ttgatagtct gggtagaaga
    99061 ggataccatc tccatttagg tcaatgctat tgtcaagctg ttgagcatgg taagtcgcgt
    99121 cattggattt tctaaaaaga cgaacagcag catagagggg ataaatcccc aaatccatga
    99181 gggctccacc agcaaaacgg tctgaaaaga catttggtgt ttgtccagtc aacaagtcag
    99241 gcatcttgga agagtatttg gcatagttga aatctgctcc taacacttgc ttatctgcta
    99301 aaaagttttt gatagtagta aaggctttct cgtggtaatt acgagctgct tcaaagataa
    99361 aacagttatt tttttcagct gtttgaatca aatcaaacca ttcttgtggt tgagtgacag
    99421 ctggcttttc gagaataaca tgtttaccag cagacaaggc agcttttgcc tgagcaaaat
    99481 gtaaggagtt tggactggcg atatagacta aatcaaaaga agatttgaag aagacttcta
    99541 attgatcgaa tagttggata ttctgatagc gagaagcaaa ggttgctgca gtttctagtt
    99601 ttctagaata gattgcgacc agttggtatt ctccactggt atgggctgct tctatgaaat
    99661 gatggctgat agcgccagtt ccgatgacac ctaattttag cataaatact ccttttccga
    99721 ttttaaatcc ttctttcatt ataacataga tagacgggac tatccaacag agaggagaaa
    99781 atttcaaata agctattagc tttcttctga agaaaagctt tcttttccga ataaatagat
    99841 agaagcatag aatctagcaa acctagattt aaaaatgtgc tataatagaa ggaggaaaag
    99901 gaggattctc agacatccgg gtatcagccc aactaatgat ttgtcaattt atccgcgata
    99961 tgctggactt gccagcaaaa aatgtgacga ttttggaggg aagtaacatt cacgtcttgc
   100021 cttccatgcc ctactcagcg caggatttct atactagtat agacgtcttg gcggagttag
   100081 ataatggaat ccaagttatc atcgaaattc aggttcatca tcagaatttt ttcatcaatc
   100141 gcctatgggc ttatctgtgc agttaggtta atcaaaacct agaaaaaatt cgccaacgtg
   100201 aaggtgatac ccaccagagc tacaaacaaa tcgcactagt atacgctatc gcaattgtcg
   100261 atagtaatta cttctcagat gacctagctt ttcatagttt tatagtaaaa tgaaatgaga
   100321 acaggacaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtataggt
   100381 ctactattct agcttcaatc tactagaaat tccatagata gaaaactaca taatctctac
   100441 agatacggat gttggagttg atgtaagatg ctttggcttg ctagaggaat tgtggattgc
   100501 caaattgtat cattgaaatt attgctcaaa tttgttatga tataaatatg aataaaagta
   100561 gactaggacg tggcagacac gggaaaacga gacatgtatt attggctttg attggtattt
   100621 tagcaatttc tatttgccta ttaggcggat ttattgcttt taagatctac cagcaaaaaa
   100681 gttttgagca aaagattgaa tcgctcaaaa aagagaaaga tgatcaattg agtgagggaa
   100741 atcagaagga gcattttcgt caggggcaag ccgaagtgat tgcctattat cctctccaag
   100801 gggagaaagt gatttcctct gttagggagc tgataaatca agatgttaag gacaagctag
   100861 aaagtaagga caatcttgtt ttctactata cagagcaaga agagtcaggt ttaaagggag
   100921 tcgttaatcg taatgtgacc aaacaaatct atgatttagt tgcttttaag attgaagaga
   100981 ctgaaaagac cagtctagga aaggttcact taacagaaga tgggcaacct tttacacttg
   101041 accaactgtt ttcagatgct agtaaggcta aggaacagct gataaaagag ttgacctcct
   101101 tcatagagga taaaaaaatg gagcaagacc agagtgagca gattgtaaaa aacttctctg
   101161 accaagactt gtctgcatgg aattttgatt acaaggatag tcagattatc ctttatccaa
   101221 gtcctgtggt tgaaaattta gaagagatag ccttgccagt atctgctttc tttgatgtta
   101281 tccaatcttc gtacttactc gaaaaagatg cggccttgta ccaatcttac tttgataaga
   101341 aacatcaaaa agttgtcgct ctaacctttg atgatggtcc aaatccagca acgaccccgc
   101401 aggtattaga gaccctagct aaatatgata ttaaagcgac tttctttgtg cttgggaaaa
   101461 atgtttctgg gaatgaggac ttggtgaaga ggataaaatc tgaaggtcat gttgttggaa
   101521 accatagttg gagccatcct attctctcgc aactatctct tgatgaagct aaaaagcaga
   101581 ttactgatac tgaggatgtg ctaactaaag tgctgggttc tagttccaaa ctcatgcgtc
   101641 cgccttatgg agctattaca gatgatattc gcaatagcct cgatttgagc tttattatgt
   101701 gggatgtgga tagtctggac tggaagagta aaaatgaagc agctattttg acggaaattc
   101761 agcatcaagt agctaacggc tctatcgttt tgatgcatga tattcacagt ccgacagtca
   101821 atgccttgcc aagggtcatt gagtatttga aaaatcaagg ttataccttt gtgaccatac
   101881 cagagatgct caatactcgc ctaaaagctc atgagctgta ttatagtcgt gatgaataag
   101941 caagaaaaaa taggtctgtc agatatgtga tagacttatt ttttacaaaa gatagtacta
   102001 cttaaaaaat gttttatgct ataattgatg aataatactc aatgaaaatc aaagagcaaa
   102061 ctaggaaact agctgcaggt tgctcaaaac agtgttttga ggttgtggat agaactgacg
   102121 aagtcagtaa caatacctac ggcaaggcga cgttgatgtg gtttgaagag agtataaaat
   102181 agaaggagaa gcatatgaat acctatcaat taaataatgg agtagaaatt ccagtattgg
   102241 gatttggaac ttttaaggct aaggatggag aagaagccta tcgtgcagtg ttagaagcct
   102301 tgaaggctgg ttatcgtcat attgatacgg cggcgattta tcagaatgaa gaaagtgttg
   102361 gtcaagcaat caaagatagc ggagttccac gtgaagaaat gttcgtaact accaagcttt
   102421 ggaatagtca gcaaacctat gagcaaactc gtcaagcttt ggaaaaatct atagaaaaac
   102481 tgggcttgga ttatttggat ttgtatttga ttcattggcc gaacccaaaa ccgctcagag
   102541 aaaatgacgc atggaaaact cgcaatgcgg aagtttggag agcgatggaa gacctctatc
   102601 aagaagggaa aatccgtgct atcggcgtta gcaattttct tccccatcat ttggatgcct
   102661 tgcttgaaac tgcaactatc gttcctgcgg tcaatcaagt tcgcttggcg ccaggtgtgt
   102721 atcaagagga agtcgtagct tactgtcgtg aaaagggaat tttattggaa gcttgggggc
   102781 cttttggaca aggagaactg tttgatagca agcaagtcca agaaatagca gcaaatcacg
   102841 gaaagtctgt tgctcagata gccttggcct ggagcttggc agaaggattt ttaccacttc
   102901 caaaatctgt cacaacctct cgtattcaag ctaatcttga ttgctttgga attgaactga
   102961 gtcatgagga gagagaaacc ttaaaaacga ttgctgttca atcgggtgct ccacgagttg
   103021 atgatgtgga tttctagaaa atcataaaaa gaattgtaca ttattctaat ttttgatata
   103081 atagtcagca ggaaagaaag tcttatggcg ttcttcaagc gagcttggga cagtgggagc
   103141 caagtagggc aaaataatga gctggcgctt tctgtagtat tttcaaaaac aatgaagtaa
   103201 taaattaggg tggaaccgcg tttctgacgc ccctagtcgc aaggcttggg tgttgaaagg
   103261 tggttctttt tgaattttat actatataga atttatcaag gaggtaattg tattgaaaga
   103321 aatttctcaa atatcatttg atacaaaata taaat
//
LOCUS       DAVMJI010000002        89256 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.002, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000002 DAVMJI010000000
VERSION     DAVMJI010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 89256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89256
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.002"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(91..228)
                     /locus_tag="VYR58_000109"
     CDS             complement(91..228)
                     /locus_tag="VYR58_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621345.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            486..605
                     /locus_tag="VYR58_000110"
     CDS             486..605
                     /locus_tag="VYR58_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV3621346.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(701..2047)
                     /gene="glnA"
                     /locus_tag="VYR58_000111"
     CDS             complement(701..2047)
                     /gene="glnA"
                     /locus_tag="VYR58_000111"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV3621347.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="VYR58_000112"
     CDS             complement(2084..2440)
                     /gene="glnR"
                     /locus_tag="VYR58_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV3621348.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(2517..3044)
                     /locus_tag="VYR58_000113"
     CDS             complement(2517..3044)
                     /locus_tag="VYR58_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV3621349.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3180..4376)
                     /locus_tag="VYR58_000114"
     CDS             complement(3180..4376)
                     /locus_tag="VYR58_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV3621350.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(4466..9376)
                     /locus_tag="VYR58_000115"
     CDS             complement(4466..9376)
                     /locus_tag="VYR58_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV3621351.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTSAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQKPKKNYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKIGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHEISTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLDAKPNHPSGSALAPLLEKNK
                     VLVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            9669..11300
                     /locus_tag="VYR58_000116"
     CDS             9669..11300
                     /locus_tag="VYR58_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV3621352.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(11860..13467)
                     /locus_tag="VYR58_000117"
     CDS             complement(11860..13467)
                     /locus_tag="VYR58_000117"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV3621353.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPVADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYANDAEVKINWINAND
                     VTAENVVELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDVEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(13857..14444)
                     /locus_tag="VYR58_000118"
     CDS             complement(13857..14444)
                     /locus_tag="VYR58_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV3621354.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(14572..15021)
                     /locus_tag="VYR58_000119"
     CDS             complement(14572..15021)
                     /locus_tag="VYR58_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3621355.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15026..15415)
                     /locus_tag="VYR58_000120"
     CDS             complement(15026..15415)
                     /locus_tag="VYR58_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV3621356.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15443..16069)
                     /locus_tag="VYR58_000121"
     CDS             complement(15443..16069)
                     /locus_tag="VYR58_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV3621357.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVIFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVFASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16083..16646)
                     /locus_tag="VYR58_000122"
     CDS             complement(16083..16646)
                     /locus_tag="VYR58_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV3621358.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(16811..17045)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17099..17602)
                     /locus_tag="VYR58_000123"
     CDS             complement(17099..17602)
                     /locus_tag="VYR58_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV3621359.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFMSQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(17795..18625)
                     /locus_tag="VYR58_000124"
     CDS             complement(17795..18625)
                     /locus_tag="VYR58_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV3621360.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(18610..20292)
                     /locus_tag="VYR58_000125"
     CDS             complement(18610..20292)
                     /locus_tag="VYR58_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621361.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(20394..20651)
                     /locus_tag="VYR58_000126"
     CDS             complement(20394..20651)
                     /locus_tag="VYR58_000126"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621362.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(20658..21206)
                     /locus_tag="VYR58_000127"
     CDS             complement(20658..21206)
                     /locus_tag="VYR58_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV3621363.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21221..22069)
                     /locus_tag="VYR58_000128"
     CDS             complement(21221..22069)
                     /locus_tag="VYR58_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV3621364.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22258..23607
                     /gene="trkA"
                     /locus_tag="VYR58_000129"
     CDS             22258..23607
                     /gene="trkA"
                     /locus_tag="VYR58_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV3621365.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            23611..25050
                     /locus_tag="VYR58_000130"
     CDS             23611..25050
                     /locus_tag="VYR58_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV3621366.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(25175..25432)
                     /locus_tag="VYR58_000131"
     CDS             complement(25175..25432)
                     /locus_tag="VYR58_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEV3621367.1"
                     /translation="MNEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILAPQVRSYYRE
                     MKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            26192..26362
                     /locus_tag="VYR58_000132"
     CDS             26192..26362
                     /locus_tag="VYR58_000132"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV3621368.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            26974..27258
                     /locus_tag="VYR58_000133"
     CDS             26974..27258
                     /locus_tag="VYR58_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621369.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            27251..27489
                     /locus_tag="VYR58_000134"
                     /pseudo
     CDS             27251..27489
                     /locus_tag="VYR58_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27585..27803
                     /locus_tag="VYR58_000135"
     CDS             27585..27803
                     /locus_tag="VYR58_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621370.1"
                     /translation="MMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(28170..30494)
                     /gene="pflB"
                     /locus_tag="VYR58_000136"
     CDS             complement(28170..30494)
                     /gene="pflB"
                     /locus_tag="VYR58_000136"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV3621371.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            30842..31903
                     /gene="dinB"
                     /locus_tag="VYR58_000137"
     CDS             30842..31903
                     /gene="dinB"
                     /locus_tag="VYR58_000137"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV3621372.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(32050..32895)
                     /locus_tag="VYR58_000138"
     CDS             complement(32050..32895)
                     /locus_tag="VYR58_000138"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV3621373.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            33151..34019
                     /locus_tag="VYR58_000139"
                     /pseudo
     CDS             33151..34019
                     /locus_tag="VYR58_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(34320..36209)
                     /locus_tag="VYR58_000140"
     CDS             complement(34320..36209)
                     /locus_tag="VYR58_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV3621374.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRGA
                     KAADEKRIQARGIQLKSSFEAVLKEMQEGVRKRVVFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            36347..37912
                     /locus_tag="VYR58_000141"
     CDS             36347..37912
                     /locus_tag="VYR58_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV3621375.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            37912..38652
                     /locus_tag="VYR58_000142"
     CDS             37912..38652
                     /locus_tag="VYR58_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV3621376.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(38761..38976)
                     /locus_tag="VYR58_000143"
     CDS             complement(38761..38976)
                     /locus_tag="VYR58_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621377.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(39847..41097)
                     /gene="ilvA"
                     /locus_tag="VYR58_000144"
     CDS             complement(39847..41097)
                     /gene="ilvA"
                     /locus_tag="VYR58_000144"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV3621378.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(41147..41503)
                     /locus_tag="VYR58_000145"
     CDS             complement(41147..41503)
                     /locus_tag="VYR58_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV3621379.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEIFGDE"
     gene            complement(41741..41977)
                     /locus_tag="VYR58_000146"
     CDS             complement(41741..41977)
                     /locus_tag="VYR58_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621380.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            complement(42084..43106)
                     /gene="ilvC"
                     /locus_tag="VYR58_000147"
     CDS             complement(42084..43106)
                     /gene="ilvC"
                     /locus_tag="VYR58_000147"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV3621381.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(43172..43648)
                     /gene="ilvN"
                     /locus_tag="VYR58_000148"
     CDS             complement(43172..43648)
                     /gene="ilvN"
                     /locus_tag="VYR58_000148"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV3621382.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(43641..45341)
                     /locus_tag="VYR58_000149"
     CDS             complement(43641..45341)
                     /locus_tag="VYR58_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV3621383.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(45541..47208)
                     /locus_tag="VYR58_000150"
     CDS             complement(45541..47208)
                     /locus_tag="VYR58_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV3621384.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(47211..47576)
                     /locus_tag="VYR58_000151"
     CDS             complement(47211..47576)
                     /locus_tag="VYR58_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV3621385.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(47733..47921)
                     /locus_tag="VYR58_000152"
     CDS             complement(47733..47921)
                     /locus_tag="VYR58_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV3621386.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(48037..48213)
                     /locus_tag="VYR58_000153"
     CDS             complement(48037..48213)
                     /locus_tag="VYR58_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV3621387.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAISLAAVRDDFYTHNFNSGILLIN
                     NGMWRAENVTQDLI"
     gene            complement(48324..48521)
                     /locus_tag="VYR58_000154"
     CDS             complement(48324..48521)
                     /locus_tag="VYR58_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV3621388.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(48775..50319)
                     /locus_tag="VYR58_000155"
     CDS             complement(48775..50319)
                     /locus_tag="VYR58_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV3621389.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            50532..50834
                     /gene="gatC"
                     /locus_tag="VYR58_000156"
     CDS             50532..50834
                     /gene="gatC"
                     /locus_tag="VYR58_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV3621390.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            50834..52300
                     /gene="gatA"
                     /locus_tag="VYR58_000157"
     CDS             50834..52300
                     /gene="gatA"
                     /locus_tag="VYR58_000157"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV3621391.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKHSEETIYQVAAAFEATTGYHKQQPVIFGGDN"
     gene            52300..53742
                     /gene="gatB"
                     /locus_tag="VYR58_000158"
     CDS             52300..53742
                     /gene="gatB"
                     /locus_tag="VYR58_000158"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV3621392.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            53871..54431
                     /gene="efp"
                     /locus_tag="VYR58_000159"
     CDS             53871..54431
                     /gene="efp"
                     /locus_tag="VYR58_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV3621393.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            54453..54842
                     /locus_tag="VYR58_000160"
     CDS             54453..54842
                     /locus_tag="VYR58_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV3621394.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            54835..55257
                     /gene="nusB"
                     /locus_tag="VYR58_000161"
     CDS             54835..55257
                     /gene="nusB"
                     /locus_tag="VYR58_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV3621395.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(55304..55540)
                     /locus_tag="VYR58_000162"
     CDS             complement(55304..55540)
                     /locus_tag="VYR58_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3621396.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(55553..56026)
                     /locus_tag="VYR58_000163"
     CDS             complement(55553..56026)
                     /locus_tag="VYR58_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621397.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(56044..56229)
                     /gene="briC"
                     /locus_tag="VYR58_000164"
     CDS             complement(56044..56229)
                     /gene="briC"
                     /locus_tag="VYR58_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV3621398.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(56388..57155)
                     /locus_tag="VYR58_000165"
     CDS             complement(56388..57155)
                     /locus_tag="VYR58_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV3621399.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(57152..58018)
                     /locus_tag="VYR58_000166"
     CDS             complement(57152..58018)
                     /locus_tag="VYR58_000166"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV3621400.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(58055..59422)
                     /gene="accC"
                     /locus_tag="VYR58_000167"
     CDS             complement(58055..59422)
                     /gene="accC"
                     /locus_tag="VYR58_000167"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV3621401.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGYVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(59434..59856)
                     /gene="fabZ"
                     /locus_tag="VYR58_000168"
     CDS             complement(59434..59856)
                     /gene="fabZ"
                     /locus_tag="VYR58_000168"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV3621402.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSENTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(59853..60338)
                     /locus_tag="VYR58_000169"
     CDS             complement(59853..60338)
                     /locus_tag="VYR58_000169"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV3621403.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(60341..61576)
                     /gene="fabF"
                     /locus_tag="VYR58_000170"
     CDS             complement(60341..61576)
                     /gene="fabF"
                     /locus_tag="VYR58_000170"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV3621404.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEVNVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(61598..62329)
                     /gene="fabG"
                     /locus_tag="VYR58_000171"
     CDS             complement(61598..62329)
                     /gene="fabG"
                     /locus_tag="VYR58_000171"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV3621405.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(62363..63283)
                     /gene="fabD"
                     /locus_tag="VYR58_000172"
     CDS             complement(62363..63283)
                     /gene="fabD"
                     /locus_tag="VYR58_000172"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV3621406.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSNFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(63276..64250)
                     /gene="fabK"
                     /locus_tag="VYR58_000173"
     CDS             complement(63276..64250)
                     /gene="fabK"
                     /locus_tag="VYR58_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV3621407.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(64369..64593)
                     /locus_tag="VYR58_000174"
     CDS             complement(64369..64593)
                     /locus_tag="VYR58_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV3621408.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(64653..65627)
                     /locus_tag="VYR58_000175"
     CDS             complement(64653..65627)
                     /locus_tag="VYR58_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV3621409.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(65627..66061)
                     /locus_tag="VYR58_000176"
     CDS             complement(65627..66061)
                     /locus_tag="VYR58_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV3621410.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(66155..66940)
                     /locus_tag="VYR58_000177"
     CDS             complement(66155..66940)
                     /locus_tag="VYR58_000177"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV3621411.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            67310..68674
                     /locus_tag="VYR58_000178"
     CDS             67310..68674
                     /locus_tag="VYR58_000178"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV3621412.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            68677..69048
                     /locus_tag="VYR58_000179"
     CDS             68677..69048
                     /locus_tag="VYR58_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV3621413.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            69262..70536
                     /gene="serS"
                     /locus_tag="VYR58_000180"
     CDS             69262..70536
                     /gene="serS"
                     /locus_tag="VYR58_000180"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV3621414.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(70561..71460)
                     /locus_tag="VYR58_000181"
     CDS             complement(70561..71460)
                     /locus_tag="VYR58_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV3621415.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDMLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPERRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(71570..72118)
                     /locus_tag="VYR58_000182"
     CDS             complement(71570..72118)
                     /locus_tag="VYR58_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV3621416.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(72336..73658)
                     /locus_tag="VYR58_000183"
     CDS             complement(72336..73658)
                     /locus_tag="VYR58_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV3621417.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSYFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(73749..73837)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(74001..76337)
                     /locus_tag="VYR58_000184"
     CDS             complement(74001..76337)
                     /locus_tag="VYR58_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV3621418.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFSDIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(76441..76989)
                     /locus_tag="VYR58_000185"
     CDS             complement(76441..76989)
                     /locus_tag="VYR58_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV3621419.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(76986..77288)
                     /gene="zapA"
                     /locus_tag="VYR58_000186"
     CDS             complement(76986..77288)
                     /gene="zapA"
                     /locus_tag="VYR58_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV3621420.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            77375..78256
                     /locus_tag="VYR58_000187"
     CDS             77375..78256
                     /locus_tag="VYR58_000187"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV3621421.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            78260..78874
                     /gene="lepB"
                     /locus_tag="VYR58_000188"
     CDS             78260..78874
                     /gene="lepB"
                     /locus_tag="VYR58_000188"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV3621422.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            79002..81368
                     /locus_tag="VYR58_000189"
     CDS             79002..81368
                     /locus_tag="VYR58_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV3621423.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGITGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDAEFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(81416..82699)
                     /locus_tag="VYR58_000190"
     CDS             complement(81416..82699)
                     /locus_tag="VYR58_000190"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV3621424.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLTELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(83505..84641)
                     /locus_tag="VYR58_000191"
     CDS             complement(83505..84641)
                     /locus_tag="VYR58_000191"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV3621425.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(84703..85140)
                     /locus_tag="VYR58_000192"
     CDS             complement(84703..85140)
                     /locus_tag="VYR58_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV3621426.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(85142..87097)
                     /locus_tag="VYR58_000193"
     CDS             complement(85142..87097)
                     /locus_tag="VYR58_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV3621427.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKLEEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(87121..88890)
                     /locus_tag="VYR58_000194"
     CDS             complement(87121..88890)
                     /locus_tag="VYR58_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV3621428.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHINVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATKAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            89099..>89256
                     /locus_tag="VYR58_000195"
     CDS             89099..>89256
                     /locus_tag="VYR58_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV3621429.1"
                     /translation="MKLTYDDKVQIYELRKQGYILEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKG"
BASE COUNT        26456 a        19803 c        16555 g        26442 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 agcctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttgacaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattaa tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagta aacttgtaga tttcgatttg aagtaacttg
      481 ttttcttgcc cgatattgtt tttgaaattg aatttttcca tagtgactcc ttgattttct
      541 tctacacgtc tgatgataaa tctaattcgc aaaagagtca agaggatttt tcgaaaaata
      601 aatagcgacc gaaatcgcta ttttaagggt tataggtatt tgatggctta gactgctgtg
      661 tgactgttta cccacaggca atctttcttc tatattagta ttagtaaagg tctaaataat
      721 tatcaatttc ccattgtgaa acgaaggttg cataacttgc ccattcgatt cgtttggctt
      781 caaggaagct agtatagatg tgatctccga gagcagcttt aaccacttca tcttctgtca
      841 aagctttcaa agcgttgtga agagttgatg gaaggtctgt aataccagct tccttgcgct
      901 cttctgctgt catgatgtag atattttctt cgataggagc tggtgcttcg attttatttt
      961 caataccata caaaccaact tccaaaagaa cagccatagc aacgtaaggg ttcgccattg
     1021 gatccactga acgcaactca agacgagttc ccataccacg tgaagcaggt acgcgcacaa
     1081 gtggcgaacg gttacgacca gcccaagcaa tgtaaacagg cgcttcataa cctggaacca
     1141 aacgtttgta tgagttaact gttgggttca tgatggcagt atagttgtaa gcatgcttga
     1201 tcaaaccgcc taggaaatgg taagctgttt ctgacaactg cattcctttt ggatcatttg
     1261 gatcaaagaa ggcgttattt ccttctgcat caaacaagga catattacag tgcatacctg
     1321 atccagcaat accaaatttt ggcttcgcca taaatgttgc gtaaagtccg tgtttgcgag
     1381 caatggtttt aacaacaagc ttaaagattt gaatcttatc acaagcacgg agaacttcat
     1441 cgtacttaaa gtcaatctca tgctgtccaa ccgcaacctc gtggtgactc gcttctactt
     1501 caaatcccat tttggtcaag acattcacaa tctcacgacg tgtgttgtcc gcaaggtcag
     1561 taggtgccaa atcaaagtag ccacccttgt cattcacttc aagtgttggg tccccatttt
     1621 catccaactt aaataggaag aattctggct ctggaccaag gttgaaggat ttgaatccaa
     1681 cttcttccat gtgacgaaga gctcgtttca aattaccacg agggtcaccc gcaaatggtt
     1741 caccttctgt tgtatagaca tcacagatca gacctgcaac acttccattt tcatctcccc
     1801 aagggaagac tgtccatgta tccaagtccg gatacaagta catatccgac tcattgatac
     1861 gtacaaaacc ttcaatagaa gatccatcaa acataacctt gttcgacaag accttatcta
     1921 actgttcatc tgtagcagga atttcgacgt ttttcatggt tcccaaaata tctgagaaca
     1981 taagacgaat aaaggtaaca tttttttcct tgacttcacg acgaatatct gcagctgtga
     2041 ttggcataag ttttctcctt aatctatgac tacttgcggt tgcctaaccg cgaccaaaag
     2101 gtgactgtac tgaagcaaaa cgcccctgtt ggaggagttc attgtgaagt gcacgacgta
     2161 cttcagtctg actaaccgct ttcttggatt tcgcttcacg ttcagcatat tttttcttaa
     2221 tggcagcgat attataacct tcagagatat aatctttgat ttcaagcaga cgatccatgt
     2281 cattcaagga atacatgcga cgatttcctt cgtttcgatc gggcttgatc aactcttgat
     2341 cttcataata acgaatctga cgcgccgata gatcggtcaa cttcataaca ctgccgatag
     2401 gaaaaacagc catatttcgg cgaaattctt tttccttcat ttacaatttc cttctttctg
     2461 tctattatag tctaaaaaaa gacaaacgtc aattgataat gttataaaat gtaacattat
     2521 ttttcttttt tctctaaaaa gagacgaata cgatcaatat cgtaatttac gataattgca
     2581 acaaaaactc ccataaacgt ttctgataca cgcacaaaca cgtacgaaat tgtctcacca
     2641 cttggaattg atagggtaat gattaacata gctgctacac caccaataac ccctgctttg
     2701 ttattcatgg ctacatttgt cataatggtt aacatggtgc agattggaac aactaccaag
     2761 gtcacccaaa aggcttcgtg gaaaaaggta tttaataaga agaagaccaa ggcatagagt
     2821 ccaccgatac tatttcctag aatacgcgaa gtcccaaaat gaacactctc atcaaaactc
     2881 tccctcaggc taaaaacggc tgtcaaagca ccaatttgaa gacctttcca gccaaaaaag
     2941 ccaaaaatca agagaactag aaaaacagca atacctgttt taaaggttcg cataccaagt
     3001 ttgaactggg atttatcgaa tttatatttt ttaaaataac tcataatctc aactttctat
     3061 ttccatttta tcataaatcg gtgattttta tgagtaatag ttgagaggaa gcgtttttat
     3121 tttaagcaaa agaaaagagg aactttcatc cctctcttct ttgatttgtt tataaaatct
     3181 tatttttctg tcaaggctgc aagtcctgga agaaccttac cttcaagaag ttccattgat
     3241 gctccaccac ccgtactaat ccatgagaac ttgtctgcac ggccaaggtt aatcgctgcg
     3301 gcagctgagt caccaccacc gatgattgat ttaactcctg gttgtttcac gatagcgtcc
     3361 atcacaccga ttgtaccagc ttggaaatct gggttttcaa atacacccat aggtccgttc
     3421 catacaactg ttttggcacc agtcaaagct tcgtcaaatt tggcgataga ttttggaccg
     3481 atgtcaagac caaggaagcc ttcagaaact gcttcacctt cagtgtcacg cacttcagtg
     3541 taaccagcaa atgcgttagc ttcttttgag tcaactggca agatcaattt accatttgct
     3601 ttttcaagaa gagctttcgc aacatccaat ttgtcttctt ctacaagtga gttaccgatt
     3661 tcgatacctt gtgctttgta gaatgtgtaa gtcatcccac caccgataag gactttatca
     3721 gctttttcaa gcaagttttc gataacaccg atcttgtctg aaacttttga accaccaagg
     3781 atagccacga atggacgttc tggagtttca actgcttctt ggatgtaggc aatttcgttt
     3841 tcaagaagga aaccagcaac tgctttttca acgtttgctg agataccaac gttagatgcg
     3901 tgtgcacggt gagctgtacc gaatgcatcg tttacgaaga taccatctcc aagtgatgcc
     3961 cagtatttac caagttcagg atcgttttta gattctttct tgccgtcaac atcttcgtaa
     4021 cgagtgtttt caaccaagag aacttgtcca tcttcaagag cgttgattgc cgcttccaat
     4081 tcagcaccac gagtgacacc tgggaaaaca acatcttgac caagttttgc tgccaagtca
     4141 gctgctacag gagcaagtga tttaccagct ttatcagctt cttctttcac acgtccaagg
     4201 tgagagaaaa gaattgcacg tccaccttgt tcgatgatgt acttaatagt tggaagagct
     4261 gctgtgatac ggttatcgtt agtgattacg ccatctttca atggtacgtt gaagtcaaca
     4321 cgaacgagga cttttttacc tttcaagtca acgtctttaa cagtaagttt tgccatgtta
     4381 caaaaactcc tttatttatt ttattcgaaa ctattatatc acactttaga aatataagga
     4441 aagatttcac aagatttttc gatatttaat ctttatcttc tcttttccgt ctcaaggtca
     4501 aggctaaact agcaagacca aggctggcta agcctgctat tagggcttca ttagcatcag
     4561 ctgttcctgt atttggcaat tgtttgcttg cttcttctga tttaactgct gtattttgag
     4621 ctggtttttc ctgtgtagct actactgctg gtactgtttt tacttttgtt ccaatttcaa
     4681 caatttctgg aatcgcttct tggatgactt ctgttgaacg aagacgacgc tgaccgtttt
     4741 catcaacttc aaagacatgt cttaacagtc catctcgtcc ctgtatgatg actcgttgtt
     4801 ccccaactag catctcagca ttttcatgct cttgacgatg aaaggcaacc ttttcctctt
     4861 gaacttccaa tttaggagcc ttttgttgat cagaagccgg ttgataagta ggttttggaa
     4921 ggactgtgtt ttgtggtgct ggtttagcag gttgtggttt ttcagcagat tcataaacaa
     4981 aggcataatg agtaaagtga ggtgctgtaa agataacatg actatccgtt tgttcaaaag
     5041 ccaattctac tgcctctttg ccttcaggta agaaaaatac tttcttaact ttcttatctt
     5101 tttcaattgg gattttcaca atagaagcat aagagagatc aacatcttga cctttttcat
     5161 ccaaaccttc tatttcaaag acatgagcat cttctccagc aaagtatttc ttctcttcag
     5221 cacttgcttg aacacgctct actttcaaac ccttgatgac agtcttctct ttatttgaga
     5281 agtgtacttc aacacctgtt ttactatcag aaaagactgc tggcttgtct tctttcaata
     5341 aagcaaccag atcttttaga ctctgtttcg ctgttgcaag ctcttctgga ctcaaatcta
     5401 ctttttcaac caagaccttg tttttctcaa gaagcggagc tagggcagaa cctgaaggat
     5461 ggtttggttt ggcatccaag agttcttgaa cctcacctgt taaacgatca agctctgtct
     5521 tttcttcctt aaatttctct tgaccattca gagctttatg agcttctgtc aatttattaa
     5581 gtcggtcatt gacttgatct tgggtgctaa tttcatggtc tttcaacact tgttcggccg
     5641 cttcaattgc tttcaagaaa gcttctttta cttctggtga agcaaagtta tagaccacct
     5701 tgttcttagc agcttcaact tctgctaatt tttgtttgag gtactcatcg ttcaatgctg
     5761 cttttggaga taccaaaaca tcaaagttga cttcatgacc ttggtaacga agcgtcaagg
     5821 tttgacgacc aatcttttga gcatcgtaac cagaaatttc aactccctca tcagtaaagg
     5881 aatgttcttc catggtgtca ttgctataag ccactgcaaa gcgtccttca gacaagtcta
     5941 agctatcacc aactaggtaa ttttttttcg gtttctgact tacttcaatt cccaaaatag
     6001 ttttcggact tgcttcgtct tggccagtga cagtcactga caaattagca tttactggtt
     6061 gtcccaaata ttggagagta agattctgtt ctcccttatg atgcgtatca aaacctgata
     6121 ctgatacacc tgcgtgagtt aggcgaatga gttcgtcctc agttcctcct tcatactgaa
     6181 ctcgaagaac accacctcta aggtccaaat cctccccttc ggcgtagctt gttttcttag
     6241 gtcctgtttc taggctgact gacttgattc ttctgtcatc ttttggaacg gaaactgcta
     6301 ggacattact aatttccttg cctggcaact gggtacgata ataaagaaga ccagattgat
     6361 ttgtcaaatc caatggtgca cttgctaggt ctcctccaac ttcgctcttc aaggttgcaa
     6421 gcggagtttg agaatttgga ttatcataaa cggtaatagt tgctccagcc ggtacatctg
     6481 caaagccaac ttgtaccttg ttattgccta gagaacgggc tgcagccttg gccatcggaa
     6541 tattgacact ctcagtatca agcttttcat acattttcca gttatagata cgaatagcct
     6601 tccatggagt tccattgtca gaagtgacaa cattcaagcg ccagtcttga gcagtgattg
     6661 gtttatcaag agtgatatct gtcacgtgtg ctttgttgcc acggacttcc ttagctagct
     6721 tccactcacc atctgcatct ttataataaa ggtcaaagtc tttggtgttc atcaagccat
     6781 cgttaacaga ctcaccacca gcccctgcat gatccatgac ccatctaaca acggtacgtg
     6841 gcttggtcaa acgaatatcc acactaccac tcaactgagc tgaagaccat ttatctgaca
     6901 agctagtaat ggtaccgttc aacatacctt caataccttc tccaccttct gtatctggga
     6961 aggtacttcc gataacagta gcccctggaa cgatgttttc tgctagaggt cttggaagac
     7021 ttgtgtcttg gacagtcatc ccccactcaa aggttgtggt tgcagcttct gaacgaactc
     7081 catttttacc gactgctaca accttcagtt cttgagttgt accctgagca cttgctgagc
     7141 ggctaacttt tggtagataa atagttgtag aagatgagcc agttagtaat ttccagctgt
     7201 ctccatcttt ttcataaact tcatagaaat ctgcatcctt gttgccttta aattgcacaa
     7261 ctgcttccgc ttcttgggca tttttaagag attgtttcac tacagaaaag cttgtcggcg
     7321 attgtggctc ttggtgattg tccgagatag ttaattgtcc gaggttgaac tgataatctt
     7381 ttacagcacc ttcatgctcg aaaaatagtt tgactgcata gatggtttta cctgctagtg
     7441 agctgagatc aaattcttca tttgtccagt tgtcagaaag ggttagctct ttccatgcat
     7501 ctgcatcatc gaatttgtag tctggagttg tagagaatgc catataaact ttagaacctt
     7561 ttcctccctt gtgggcaaca cgaagtttgg tcttctcagt tacttctaac ttagtagaat
     7621 aaagtctcac atcctgatct gtcttaccgg ctacatcacc agagaattta agggaatttc
     7681 cgccattata ggcatctgta aaatcatatt ctgcacgaag tttttcccct gttgaagtct
     7741 gccaccagcg ccatgttgga agaacacctg atactgaacg ataattccac tcagaatcct
     7801 tagaaacctt accatctacg aaccattttt taccatgacc tgtattaaaa gaagtagtaa
     7861 aagtattacc taccgctgac gtacggtccg caactaggtt agcaatacca taccaatctt
     7921 tgtcacctgg tttttggcca gtagggtctc cttgataacc tgtaaagaag atatcttcat
     7981 ttttatgata atcttcacca gtttttccta aacttgtaat ggtatctggg gcaaataaac
     8041 caagagaaag gcgcaatttc ccattttcgt ctaaaatgtc attccactta acctttgtct
     8101 tgtaggaacc accctgttgc aattccaaac ctgcaaatac atcataagga ttacgaccaa
     8161 tccagttggc agttgcaata gtgtaatcat ttttagcctt atcccagtta aagttagcaa
     8221 agaagttatc tgccggaacc ttatctcctt ctggttgcat gaattggtag ttgtattctc
     8281 ccaaaccatc ttgatggtaa cgtccatagt tataggtcat ggcatcgtac caagaatact
     8341 tgattggatg gtttacctta gcagcatatt ccttgctata gagcataaac tggcgcatct
     8401 tttctccaag aggtttaacc aaatctccag ttgtttcttg gttgatgaaa tagccatcat
     8461 agccataata cttggccatg tctaccaatt tacgggcaat tgggaagcta ccatctgcgt
     8521 cttgcttcaa agcttcagca aatctttctt gatctgcaat actattagac cagttgaaga
     8581 agagtgtacc gtatacagga accccgttac ggtgacctgc atcaataacg tcaggagttg
     8641 gtacgagacc ttcccagaag accattgaat ctagatattg ccaatagtca aaagcatagg
     8701 ccttgaactc ttctccacca acagaagcat ggtcttttgc tttagaattg gtgtttgata
     8761 aggcttgaac ttttgcttcc ttgctagctt tttcattgac taaatgacct gtccgacgtg
     8821 aagcgaggac aacagatccg cggttaatag catcatcttc acgagcacct ggttcccatt
     8881 ttaacaattc ttcccaagaa ttaaatttga tttcctttgg ttttaatgtt ttttctgtat
     8941 ttttagggac atctggctgg acttcttttt cagtcttatt agcttctgct gctggcttag
     9001 actcatcccc ttggttagtt gcttcgggct ttgcttctgt ttccttgtca gacttaggtt
     9061 ttgcttctgc agatggtgtt tctgcaacca cctcacctgc tttttcctct ggtttagctg
     9121 cgctagctgc ttctgccttt tctagcttgt tttctctagc atgttcccct tcattctgct
     9181 tatcagcttc attggtcgaa tgctcactct ctcctgaaac aagctctgta ttagctccgc
     9241 tattttcagg aactgcagtt tcttcagcca aggctggacc agcaaataaa acagcaccaa
     9301 tcatcagcga gcaggctcct actgataact tacgaatact gtaacgacaa cgtctttcaa
     9361 aaaatggatt cttcattttc tcctcctaaa agattgattt tgttgtttta aagaaagcgc
     9421 tttatattct gtagtttttt atcaaactct agaaccatga taatcacatt tttatcctaa
     9481 aacattttta gacaaaaaac aataactgtt tgcacaaatc taaaataagg ttaaaaactc
     9541 ttaaaaataa tacacttatc aattataatt ttcttttaca aacttgacat taacacttgt
     9601 tagatttact tttatccttt aaaatagaat aggagatatt ccgcgattat ttttcggagg
     9661 aaaaagaaat gtccattaat tggcaggaaa ttttatttca ctttttaggt ggtctggggc
     9721 tattcttata tagcatcaag accatgggag acggtttgca acaagctgct ggagatcgcc
     9781 ttcgttttta cattgacaaa tatactagta atcctttctt tggagttctg gttggtattg
     9841 ggatgactgc tctaattcag tctagttctg gtgtaacagt tattacagtc ggcctggtca
     9901 gtgccggtct cttaacctta cgtcaggcta tcgggattgt catgggtgct aatattggga
     9961 caactgtcac atcctttctc atcggtttta aattaggtaa ctatgcccta cctatgctct
    10021 ttatcggtgc cgtctgtctc ttttttacga aaaatcggac agtcaataat atcggacgca
    10081 tcctctttgg tgtcggtggt atcttttttg ccctcaatct catgagcggc gcaatggctc
    10141 cactcaagga tttacaggtc tttaaggact atatgattga gctaagtaag aatcctgttt
    10201 tgggtgtctt tgtcggtacc ggcttgacct tgctaattca agcttcttcg gctaccattg
    10261 ggattttaca aaacctctac gccggcaatc taattgacct acagggagct ttgccagttc
    10321 tatttggtga caatatcggg acaaccatta cagccatcat tgcctcttta ggggctaata
    10381 ttgcagctaa acgggtagca ggagctcatg ttgccttcaa cgttatcgga acagtcgtct
    10441 gcgttatttt tctagttcct tttactgtcc tgattcattg gtttgaagct acgctaaatc
    10501 tagcaccgga aatgaccatc gcctttgctc acggaacctt taatattacc aacaccattg
    10561 tccaatttcc atttatcgga gctctggctt actttgtaac caagattatt cctggagagg
    10621 acgaggttgt caaatacgaa cccttatatc ttgatgaaca tttcatcaaa caagccccat
    10681 ctatcgctct aggaaatgct aaaaaagagc tcttgcactt aggaaactac gctgctaaag
    10741 cctttgacct ttcctataag tacatcattg acttggatga aaaagttgct gaaaaagggc
    10801 ataaaaccga agaagcaatt aacaccatcg atgagcaatt aacacgttat ctcattgccc
    10861 tttcaagcga agctctcagc caaaaagaaa gtgaagtgct taccaatatc cttgattcct
    10921 cccgtgattt ggaacggatt ggagaccaca cggaggctct actcaatctg actgactatc
    10981 ttcaacggaa aaatgttgaa ttttctgatg ccgccttgaa agaattagag gaagtttacc
    11041 gtcaaactag tgactttatc aaagatgctc tggatagtgt ggaaaacaat gatattgaaa
    11101 aagcacgcag tcttgtagaa cgtcatgaag caatcaataa gatagaacgt gttctcagaa
    11161 aaacccacat caaacgcctc aacaaaggcg aatgttcaac acaagctggg gtcaacttta
    11221 tcgacatcat ctcacactac actcgtgtat cagaccacgc tatgaacctt gctgaaaagg
    11281 tttttgcaga acaaatctaa gaaccaagaa gctatccatc ataattggat ggctttttac
    11341 tttttcctaa gcaagactag gctgaatgaa actgaaagag tattctgcag atatatagta
    11401 tattgaaact agaatagtac acctctattt ctaaaacatt gttagaaatc gatttgactg
    11461 tcctgatcga tttatcctgt tattatttca ttttactata gtggattaaa ttaaaaaagt
    11521 ataatgtatt gaatctataa cagtacacct tgactgctaa aatatttcta taaattaatt
    11581 tgacttttct gatagagatg ttcatatctt atttcaattc actatacaat ccagttccta
    11641 aaactttgct agaaattgat ttggctttcc gaattaattt gttcagattt tatttcattt
    11701 caatatactg ataaatccat tcactagcac agggcaagag ggagtcgcta ttgatttcaa
    11761 gggtagcagg cacatacaaa ggactcctac ctcagatata ctgcaatatc catcgtatgc
    11821 aaaaaacctc tgagattctt ctcaaaggtt ctgattttgc taattgctgt tctcaactgc
    11881 tgcagtgaca aaggcagtgt agagctcttc tgggcgattt ggacggcttg acagttcagg
    11941 gtgatactga caagccacaa agaatttatt ttctggaatt tccacgattt ctaccaaacg
    12001 attgtctgga gaaactcctg agaagacaaa acctgctgcc tcaaactgct cacggaaagc
    12061 gttgttaaac tcatagcggt gacggtgacg gcgttgcacc acttcttgat tgtgataagc
    12121 agctgctgcc ttagagccac gttttagttt agacggataa agtcccaaac gaagggttcc
    12181 ccccatatcc tcaacatcaa tctgatcacg catgatatca atgatagggt attttgtttc
    12241 tggtgcaagc tctgcagaat tggcaccttc aagacccaaa acgtgacgag caaactcgat
    12301 acaagtcaac tgcattccca agcagactcc caacattgga acatcattct cacgcgcata
    12361 gcggatagct tggattttcc cttccgtacc acgttgaccg aaaccacctg gcacgatgat
    12421 tccgtccgca tcagacaaaa gctctaccac attctctgct gtcacatcat tggcattgat
    12481 ccaattgatt ttaacttctg cgtcattggc ataaccagag tgtttcaaag cttcaaccac
    12541 agagatgtag gcatcttgca actcaacata cttaccgaca agggaaattt taacttgttt
    12601 cttgagattc atgaccttgt ccaccattgc tgaccactct gtcatatcag ctaccggtgc
    12661 gtctaatttc aaatggtcac agacaatttg atccatacct tgagcctgca agttcagtgg
    12721 aatttggtaa agatgttcga catccaacga ttcgataacg gcttctggtg ccacatcaca
    12781 gaactgggcc agtttgtttt taattccttg accagctggc tcttctgtac gaataaccaa
    12841 catatttggt tgaattccca aaccgcgtaa ttccttgaca gaatgctgag ttggtttggt
    12901 tttcatttca ccagcagcct tgaggtaagg aagcaaggtt gtatggatgt acataacatt
    12961 atccgccccc acatctgcct tcatctgacg aagggcctct aggaatggca aggactcgat
    13021 atctcctact gttccaccaa cctctgtgat aatgacatca gagtcggtcg ttagagcggc
    13081 acgcttaatt ttttctttca aagcatctgt gatatgagga ataacctgaa cagttgcacc
    13141 aaggtattct ccacggcgtt ccttacgaag cacttcactg taaattttac cagttgtcac
    13201 gttggaatat ttgttaagat tgatatcgat gaaacgttca tagtgaccca agtccaaatc
    13261 tgtctcagct ccgtcatctg tcacaaaaac ttccccgtgc tggtaaggac tcatagttcc
    13321 cggatcaata ttgatataag ggtcaaactt ttgaatggtt actttgagac cacgattttt
    13381 caagagacgg cccagactcg ctgccacaat ccctttccca atagacgata cgacaccacc
    13441 agttacaaaa atatatttcg tagacataga ttcctctttc taaaatgctc aaggtcttgt
    13501 taactacgag gggatataga aaacaagacc ctactaataa gaataatctg ggacgactgc
    13561 accagattca caactaatac tcttcgaaaa tctcttcaaa ccgcgtcaac gtcgccttgc
    13621 cgtagatatg tgttcctgac tttgtcagtc ttatctacaa cctcaaaaca gtgttttgag
    13681 cagcctacgg ctagtttcct agcttgctct ttgattttca ttgagtataa aatacaagaa
    13741 gataacttct tgaaaaaaca aaaatagctc cctaagaact agggagcccc gacctctaaa
    13801 agaggtgccc aaacaatatg atacctaaaa ataggataat tgtcaatagc taactcttat
    13861 tcctcgctgg tttcagcgtc gtcatctgaa aactcgtcgt cgtcttcgtt gagatccaca
    13921 tcttctccca agtcatctgg agcgatttcg ttgatttctg catcataagc ttccacttca
    13981 tttttttcat catctggatt ttcatcatcg tatgaaagag ctggatctgc ttcgtatgca
    14041 tcttcgtctt ctggatcatc tgcattgtag tcaatggcat ctgaatcacc atccataaag
    14101 gcattgacac gttttttctt agcttttggt gctacttcat cgtcgtcatt ttcttcaaga
    14161 gcgatgattt cttcgtcgat ttcgtccaca ccataccatg aacgaagacc ccatttgttg
    14221 tccccaagtg agatgaagct accgtcaaag ttcaactctg tgtagaacaa aggcaaagct
    14281 tcgcggatat cgctgtttga tgttccaagg tagttttgaa tttcgtttac aagatcgcta
    14341 aaatgcatct catgatcgcg accacgaagt tctaagatag cacgcgctac ctcaatcata
    14401 gatagttcac ttttttcttg cccagcaaat acttctaatt ccaaagcgtt tctcctcatt
    14461 tatactacta tcgtcagagc gaacagactc tgacctcatt ttatcattta ctctttattt
    14521 tacgataatt ttgcggaata gtcaaaggtt aagggggaga aagtggcagg attagactaa
    14581 ttccaatata aaactccttc ctttttctgt tgctccattt tccacaaatc caagcgactt
    14641 gaaacacctc ctagaagcat gattgtaggt gtagatttcc ttgactctca attctttcca
    14701 tccttttact cgagccaatt caatcaaagc acttagaatc ttttttccaa gtcctcgatg
    14761 ttggtaagcg gaattcccaa tcacaatggg gagattatcc tgagatagtg taatatcccc
    14821 aattggaaac cattctccct tctccttgac ttcaatccaa aaaagctcac catgccgatc
    14881 caaataggaa tacatggctt ccaaggtcgc ttgactgtaa ggaagcttca ccccatctac
    14941 gaggtaaacc aagttcacat cctgatacca agcaaaagct tcctcacaat gattgacctt
    15001 ataataagga acaaaacaca atgcactacc ttttcaacaa aagagttgct gcttgattaa
    15061 aaccatcaca ccagttatac cattttgctt catacccatc ttgagctagg atacgatctt
    15121 ctaaatcaaa aacagagtaa atctttcttt cctcgcaagc ttgcgcatag agatgatata
    15181 gttcatcacc accatctcta tcccactcag cagaaatcgt atcccgacct gccaataaag
    15241 cctgataagc cctgtgatgc ccatctgtaa tcagcaaaca atctccaaag gcaagaatac
    15301 tgattggatc gacttggttt gtttctgccg actggtaaag catctgaata tcttgcaact
    15361 tcttttctga taaatatagt tgagtcggat gaagatctgc tatattgact ttcatttctt
    15421 tctcctcaag ggaattcgat actcacttct gtttgccttt aaatcgccat tggaagcgga
    15481 gcttgtcata gaagggaaac tcgataaaca ggactcccaa gcccacacag agactggcaa
    15541 agacgtctga tgggtaatga acccccagat agactcttga taccagcaca ctgactaggt
    15601 agaggccaag gacgatttgt acgatttttc tccagactgg atttttaatt cgttgactga
    15661 gaatgacaat cagagtacct accatcaaag ttacagccag agaatgccca cttgggaagg
    15721 aaaatccctt ctcttccacc agatgtaaga tagctggtcg tgggcgctgg tagatatttt
    15781 taaagatcac gattaaaaga cctgccaaag ccagatttcc cagcatgaag aaactttcta
    15841 tcttccatcg cttacgataa aagacaaaag ctgtaatgac aacccaagtg ataatcactg
    15901 ggatatcaat cagacgtgtg agggctcgaa aaagaatagt caaataatct ggtaagtctc
    15961 ctcgaatggc agtctgaatc gattggtcaa aattgaccaa catttcaggg taaaatttga
    16021 ccatatagcc aagaataacg aaaagtaaaa gggcaaaact gcccttcatt aaaaatgttt
    16081 gtttatcttt catagtgttt taaggttggt ttcaaaagga cgtacaacaa ccagaatgaa
    16141 acggaaaaga ttacaccctc aatcaagtta aaaggtaata ccatggtcat taggtagttg
    16201 gaaagtccca aaatttttcc aatatcaaag ttagcaaact tagcgtacaa aggaacagca
    16261 taaacatagt tgagaaccaa catggccaag gttaaaccaa cagttccagc tagagagcct
    16321 agtaggaaac gaagggttgt ccgttccttt ttccaaatca aagcaaatac gatgacaaaa
    16381 actcccaaag ctacgatatt catcggcaaa ccaatgtaag tattcactcc ttggctgtta
    16441 agaagcaatt tcaatagtga gcgaagcaag agcactccta gagcagcagg caaatccatg
    16501 accaccagac ccacaaggac tggcaagata ctaaattcga tcttgaggaa agatgccgct
    16561 ggtaaaagcg gaaagtcaaa gtacatcagc acaaatgaga tggctgatag aattgcaatg
    16621 gtcgaaagtc gacgtgtgtt tgtcataaca ggttcctcca attttctata aaatcagaag
    16681 aagttggaaa ggattcctct atctattctc actttttata tcccaaaagt tccctcttat
    16741 tctattaaag aaaaacaaag caagtggtta caatccggct ataaatctat caaaacagac
    16801 aaagctattc tttcgtcttc tcccatccag actatactgt cggttgtgga atctcaccac
    16861 atcagcttgc gctcgcggac ttctttaaag agaaggaaat agagattttt cttttagact
    16921 aggcgacaag ctgtaggcat aacttctggt taggcaaagc ttgtcaacaa agtataaaag
    16981 gaaaagatca tttcctagtt aaagtcaccg ccggtcggga atcacaccct gccctgaaga
    17041 ctcttttatc ataacaaaaa acgcttgcaa gcgcaagcat tttgttcatt ttcatttttt
    17101 atttcaattt atccacttca taggtatgga cgagctcaag acctgcaaag ttctgctggc
    17161 gaagagcctc atagacaatc atgcagacgg tattagacac attgagactg cggacatgtt
    17221 catcattcat gggaatacgg agagccttct caggatgttc tcgcataaaa tcttcaggta
    17281 agcccttgtc ttcacgtcca aagagaaaat aatggtcctc gtcagtcgat aaatccacct
    17341 cagaatagac tttttccgcg aatttcgaaa tcagatagag ttttcccttc atctgagaca
    17401 tgaaatcttc caaactctcg taaaaataaa tctctagctt atcccagtaa tccaatccag
    17461 cccgcttcat cttgcggtca tcaataggaa agcccatagg cttgatgatg tggaggggag
    17521 aattggtcgc agcgcaagta cgcgcgatat tgcctgtatt ttgtggaatt tgaggttcaa
    17581 ataatacaat gtgatttgtc atgacttgct tcctttcacc attgcaaaaa aatagccaca
    17641 ctgcccggag tcaagctcag caaacagcgt ggttaaggca tcgttaactt acctcacaac
    17701 aggtttgaag taaatcagcg aaactacttt cttagtataa cactttcaga atcattgtca
    17761 atagaaatga cttgattttt tcaatttttt caagctattt ccaagggttg taaaatcgtc
    17821 cctgattctg caagataagt agtaaactaa ctactaaaaa caaggttgcc aagagcaagg
    17881 taatatagtc tccttttttc aaggcctgat aactatacca tgtgcgtttt ttctctttcc
    17941 caaagcggcg aagctccatg gcagtcgcaa tagtatcaat gcgttctagc gagctaaaaa
    18001 tcaagggcgt aataatgagc agattgcctt tgattcgttg cataagagaa gctttcttgg
    18061 ataattccat cccacgcgcc tcctgagaca tcttgatagt aaagaattct tcctgcaaat
    18121 ctggaatata gcgcaaggtc aggctgacag aataagcaat cttatagggc acaccaattt
    18181 gatttaaact ggaagcaaac tgactaggat gggttgtcat caaaaagata atagccagag
    18241 gaatggtgca aagatactta atggccaaat ttagcagata aaagagctcc tggctggtta
    18301 gagtgtagac accgattccc tgccaaatca cacttctctc tccataaagt ccaaccccat
    18361 actcgggaga aaagagatag accatcaaaa cgtttaaaac ggcaaatacc gtcgcaaaaa
    18421 cggctacaaa ggaaacatct ttaaagcgaa tttctgataa atagaggaga aagactgaaa
    18481 agatggcaat cagcaagagc attctggtgt catagctaat catggccgcc aatgatacca
    18541 gaatgaaaaa gagaagtttc ccagctcctg acaagcgatg aatcacagta tctctatgct
    18601 ggtaaccgat taatttagct tgcatccctc tctcctttct ttgtaaaatg ccgttaaatc
    18661 cagtggatcc acatctagtt tcttagccaa gttaaagatg gaggtttctt ttagattggc
    18721 ttttactaac agctcaggat cgctcaacag actggctgga acagtatcgg caatcaattc
    18781 tccatccacc atgacaagga cccggtctga ataatccagc atcaattgca tatcatgggt
    18841 aatcatgaca atggtatgcc ctttttgatg taactcttcg agaaattcca taatctcagt
    18901 atagttcttc tgatcttgac ctgcagtcgg ttcatctagg agaataattt cagctcctaa
    18961 gaccaaaatt gaagcaatgg tgacacgttt tttctgacca aatgacaggg cagaaatagg
    19021 ccaattacgg aattcataaa gtccacagat tttcaaggtt tcatagactc tcgtttcaat
    19081 ttccttctca tccacacctc gcaaacggag ccctagagcc acctcatcaa aaatcatatt
    19141 ggttgaaatc atttgattag gattttgtag cacatagcct actcgttccg cccgctctgc
    19201 aacagaatcg ccttttatat cctgtttttc ccaaagatag cgtccttccg tctgaataaa
    19261 gctacttata gccttggcta gagttgattt ccctgctcca ttttttccga caatagcaat
    19321 cttttcaccc tttttaatat ctaaatgtag ggattttaaa atcggtctat catcataaga
    19381 aaaagatact tcctctagtc taaagagtga ctgcaatgct ggggtttctt ttaccagttc
    19441 cgtctgtaac tggacttgcc cttttgagat agacaagtta tccagatctg ctaattgttc
    19501 ttccttgact aagtccacac ctaattgacg gagagtcgtt agataaaggg gttctcgaat
    19561 tccattttga gtcaataaat cagtcgcaag caactggtca gggctcccat taaaaaggat
    19621 acgaccatcg tttatcaaga caatccgatc cacagggcga tgcagaacgt cctccaaacg
    19681 gtgctcgata atcagagtcg tcgtcccctc ttccttatga atctggtcaa tcaattcgat
    19741 aatatcctga cctgacttgg gatctagatt ggcgagtggc tcatcaaaca agagaatcgg
    19801 actttcatca atcaagacac cagccagact gactcgctgc ttttgtccac ctgacaaatc
    19861 ctgaggacgc tgatccagta aaggaagaag gtccagcttt tcagcccatt tataaacacg
    19921 acctttcatc tcatctaggg ctgtcacatc attttccaga gcaaacgcca aatcttctgc
    19981 cacagacaag ccaataaact gcccatctgt atcctgcaaa actgtgctaa ccagatgaga
    20041 cttatcatag atgctcatat caaaggctgt ttgacccttt atcaaaaatt ctccatatgt
    20101 ctgacccttg taaatattgg gaataatccc attcaaacac tgacccaagg tagatttacc
    20161 tgatccagat ggtccaacaa ttaagacttt ttctcccttg taaatggtca agtctatccc
    20221 ttgcaaggtc ggttcttgtt gtgtttcata ccggaaagag aaatccttcc actcaattat
    20281 agcttctttc atcttactct cttcattcgc ttcttagact tctattttat cataaatcaa
    20341 gcccttcttg cagtctcttc tcttaaaatc ttagcgccaa aaagattcct atcttagctt
    20401 acttgcctaa ctaatctata aacatcgaaa aagactagtt gcccagcctt ccccatcatt
    20461 ttatactctt cgaaaatctc ttcaaaccac gtcagcttcg ccttgccgta ggtatggtta
    20521 ctgacttcgt cagtttcatc tacaacctca aaaccatgtt ttgagctgac ttcgtcagtt
    20581 ctatccacaa tctcaaaaca ctgttttgag caacctgcgg ctaacttcct agtttgctct
    20641 ttgattttca ttgagtatta gtcctttttc aaacttcctg cacgagtttg agttcctgca
    20701 taggcaagta agagaagagt tcctgcaata gctacagata caccattggc aattcccgca
    20761 acaatccctt gtgcaaatac tttttctgcc gcttcttgat aaatcacaac atctccaagt
    20821 ggtgccaaga caccccaaac aagggcattt gcaagtagtt gaatgaggtt aaaaataaga
    20881 atatctttcc agtcaaaaac accattgatc actcgaacgt actttctaaa aagtcccaca
    20941 actaaaccaa agagtccgct agcgataatc caagtccacc atagaccata accagcaaga
    21001 gagtccttga ttgcatgacc aatcaacccg acaagcaaac cgataatcgg tccaaaaata
    21061 atagaaagta gcgcttgtac cgcatactga agctggatgc ttgtatttgg aacaggggtt
    21121 ggaatgttga tcatcccgat gacgacaaag agggcagcgc caattccgac agcaacaact
    21181 tgtttaattg taaatttgat ttccatacta ttctcctatt ttatccttct attttcttta
    21241 tttcaatggt ccaagatgaa ccgacaccta cattataggc cttggcaaag gaaccttggt
    21301 tgatagccaa acctaaacga tagagagagt tgatgtaaag gatgggttgc ccaattctca
    21361 catctgcaaa tgatttgcca tagacaacct gattttgata gaccagcata tcagcatgat
    21421 agatggtcac ttcaaaacga tcaccaaatt ctggttccag cttgtaaaat tcttcccgtg
    21481 tgatagaggt ccaaagcgaa ccgaaacgca catccagaat atcaatggct cccttcacca
    21541 gatgatcttc tatgatggtc gctacgactg gaagctctac aatctgttcc acactgagct
    21601 ctggccctac ttcctcaaaa gtaatgtgac cactggccag tttagcacca gtataggcat
    21661 agacatcacg accgtggaag gtataagaat gctctgtgtt ttgacgccta ttggccacct
    21721 cagaaatctc acgaatggct acaatgccaa cgtgtttctt gataaaggaa agcgtcccat
    21781 tatctggcgt gacaatgtat tgattttttg cagtcttggc aactacactc ttacgtttcg
    21841 aaccgacacc tggatcgaca accgatacaa acgtcgttcc ctcaggccag taatccaccg
    21901 tctgaaagag acgatagctc ccctcgaaaa tattataagg cgtgatatcg tgcgtcaagt
    21961 gatggatttt taaggttgga gactcttcta aagccactcc aatcatagcc gataccgcac
    22021 catcaaccaa accaaagtct gattgtaata ccagtaaatt attattcatt ttatctcctt
    22081 gtatatcctt tatcatacca tatttcagag aaagtcgcta atagctattt caattggtta
    22141 gggtatagtt ttaccttata gcaaatttcc tactaaaagt tcttgttatt agctagtagg
    22201 tgcatttttt cttgaaaaag ggtatgatag ttacatcatg aaaaagtagg ttttattatg
    22261 aaaattatcc ttgtcggagg gggaaaagtt ggttttgccc tctgtcgctc cttggttgca
    22321 gaaaagcatg atgttttgct gattgagcaa gacgaagctg ttctcaatca tattgtcagt
    22381 cgctttgata tcattggtat ccttggtaac ggggccgatt ttgccattct tgagcaagcc
    22441 agcgtccaag attgtgatat ctttatcgcc ctgactgagc acgatgaagt caacatgatt
    22501 gcagcagttc tagccaagaa aatgggagct aaagaaacta tcgttcgggt gcggaaccct
    22561 gaatattcta actcttattt caaggaaaaa aatattctcg gtttttctct tatcgttaat
    22621 cctgagctct tggctgcccg cgctatcgcg aatatcattg acttccccaa cgccctgtct
    22681 gtcgaacgct ttgctggtgg acgcgttagc ctcatggaat ttgtcgtcaa gtccaccagc
    22741 ggtctttgcc aaatgcccat ttctgatttt cgtaaaaaat ttggtaatgt cattgtctgt
    22801 gcgatagaga gggatcatca aattatcatt ccaagcggtg acatgactgt acaggataaa
    22861 gatagaatct ttgtcactgg taaccgtgtc gatatgatac tcttccataa ttattttaaa
    22921 tcacgcgccg tgaagagcct tctcatcgtt ggggcaggta gaattgccta ttatctactt
    22981 ggtattctca aagatagtcg tatcgataca aaagtcattg aaatcaatcc tgaaatcgcc
    23041 agcttcttta gcgagaaatt cccaaatctc tacatcgttc aaggagatgg aaccgcaaaa
    23101 gatatcctgc tggaagaaag tgctcaacac tatgatgccg ttgcgactct aacaggagtc
    23161 gatgaggaaa atctgattac ttcgatgttc cttgacaggg taggtgtaca gaaaaatatt
    23221 accaaggtca atcgtaccag tctcctcgaa attatcaatg cgcctgattt ttcaagtatc
    23281 atcacaccta aaagtattgc cgtggacacg attatgcact ttattcgtgg tcgtgttaat
    23341 gcccagtatt cagaccttca ggccatgcac catctagcca atggtcaaat cgaaaccctg
    23401 caattccata tcaaggaagc caataaaatg actgccaaac ctctttctca actgaaatta
    23461 aaaaaaggtg ttcttattgc agccatcatt cgaaagggca agactatttt ccctactggg
    23521 gaggatatgt tggaagtcgg agacaagctc ctagtaacaa ccttgttgcc aaacatcacc
    23581 aagatttatg acttgatcgc gaggtaagaa atgaataaaa gtatgattcg ttacctcctt
    23641 tcaaaattac ttttgattga agctgttctt cttttggttc ctgttgcgat tgctgtctat
    23701 taccgtgaat cgagccaagt ctttacagcc ctcttttcga ccatagggat tctcgtattg
    23761 ttaggcggtt cagggagttt acagaagcca aaaaatcaac ggatttatgc caaggaggga
    23821 gtcttgatcg ttgccctctg ttggatcctt tggtctttct ttggtggtct cccctttgtc
    23881 ttttctgggc aaatccctag ccttattgat gccttttttg aaattagttc tgggtttaca
    23941 actactggag caagtatttt gaacgacgtt tcggttctca gccgttccct cctcttctgg
    24001 cgaagtttta cccacttgat tggagggatg ggagtgcttg tttttgcact tgctattatg
    24061 gacaatgcca aaaatagcca cctagaggtg atgaaggctg aggttccagg tcctgttttt
    24121 ggcaaggttg tatccaaact aaaaaacact gcccagattc tctatctcct ttatctagct
    24181 ctcttctccc tctttgtcat catctattat ctagctggta tgcctctcta cgatagtttt
    24241 gtcattgcta tggggacagc gggaactgga ggctttaccg tctataacga cggaattgcc
    24301 cactatggca gctcactgat tacctatctg gtcagtatcg gagttctggt ttttggggta
    24361 aatttcaacc tctactacta cctcatgctc cgtcgcatca aggccttctt tggtgacgaa
    24421 gaacttcggg cttacttggt cattgtactg gtttctacag gcttgattag cctcaacacc
    24481 ctctacctct acccagggtt ttcaaagagc tttgaaatga ccttcttcca ggtttccaac
    24541 atcattacaa caactggttt tggatatgga gatattacca actggcccct cttctcccag
    24601 tttatcctcc ttttcctcat ggcaatcggt ggctctgctg gatcaactgc aggtggactc
    24661 aagattattc gaggcctcat cctttcaaaa attgccaaaa accaaatttt gtcaatccta
    24721 tcgccccacc gtgttttgac tctccatgtg aatcaaacgg tgattgataa agatacccag
    24781 cataagattc tcaagtactt tgtcatctat gctatgattt tgctagcgct tatctttatt
    24841 gtcagcctag atagcaatga ttttctggtc gtgaccagcg ctgtctttag ctgtttcaat
    24901 aatatcgggc ctattctagg aaccacttct agtttctcaa tctttagtcc catctcaaaa
    24961 attctcctct cctttgcaat gattgcaggg cgcttggaga tttacccaat cctccttctc
    25021 tttatgaaaa gaacttggtc taagagataa aatacaaaat ccctcttttt acaattgtga
    25081 aagagggatt tttatattaa aaagggggaa cgtttttaaa tccaagcctg tctgtaagca
    25141 aagttcttac tcaaataaaa gatggaaaaa cttactacac agcttggtaa tgctccaata
    25201 caaattgtaa ggctttactt ggattctttg ttaaatgaat atattccatt cctctggtag
    25261 caactatctg aatacctaat ctttctgcat ccaccttcat ctctctataa taactccgaa
    25321 cttgtggagc cagaataatt aaatcataaa cacccataat atcataatga gctccgtacg
    25381 ctcctgaatt cgcaatcact ctaacttctg ctaattgagc gccctcgtta attgcattgg
    25441 ctaattacgc acttgttcca gaccctgcac aaagaaccag tactttcaac tccttacttt
    25501 ttattacatc tatctcacca ggcattattt cacttgtatc ctcctctaaa ataatatcat
    25561 ttgagcttgc aatatctaca acctgtagta gatatctcgt atttagacaa tatgaaaaca
    25621 agacgacttc catataggaa accgccttct ctctatgttg agtgatttat attaaaataa
    25681 cttttcttct agctgcattt tattattata aaaacattca tcataaccct gaacttaaat
    25741 aacgattttt attcaagata catactccta gaataaactt tatatgaaat tctcattttt
    25801 gtttttacaa ttctccttag ttaaatcttg tttaatatat gttttacata tagtatttag
    25861 cgccacatag tactgaactc tctccaaaaa cggttattcc tctttgaata gggcgttatc
    25921 acaagaaaag catctccacg tttcaacttc atatggctca aaaacaatca attgatgcta
    25981 aaacctgtac ctagatgttt cggttcataa aaccatgaaa ctgtaaaagt ggatgaaatt
    26041 gatagcgata gtcaaatcaa gaggcatcat aactctaaaa agtcacaata tataagttca
    26101 tcctcggaaa aatatcattc taattgttga aatgcctaca tgaaaagaaa cgtcaaatgc
    26161 tcatgaaaca acgaatacag gtatcaaaac tatgacaaaa caagtcccta aatttactaa
    26221 agacactgct caactttaca cctgtaaatg gttgttgtat aataaagtta caaagatgta
    26281 cgaccacact gttgtaaatc atagtgttcg cgaatatatt actgatagca tttctacaaa
    26341 tacaattgaa gagactggat agactttaaa cgaaatatgt cagtgttttg gcattcctag
    26401 ccttcatatc atttaaagaa ttctatagac aaaatttttc ccaatacaga cactcgtaac
    26461 aactgcttca tttttctacc aacatattta ggaacaggat aagatacaag aggattaatc
    26521 catagatcag ttctatacca atctaagaca aataagctaa aaaaacgatt gataataagc
    26581 aaatagattc caaattttct ctatctgctc attttaataa acaatactag tgtaactatc
    26641 cttccagtca gaagcttgtc aaatcacacc gaaaattctt ctaaaattta tctcgttagg
    26701 caatcaagca aaaactcgac gatagtacaa acattatcat acagaattga cttcctaaat
    26761 tatatacttt agtaaggttt tcgtataaga aaaaagattc attttacatt tctaaacatt
    26821 cttttctaag atgaaaaaca gaatttttcg attgtgattt aaagcaacaa gaagattttc
    26881 agtatcatcc tatagatacg agctaattaa gaaaaactac attttcgaat ataaactaca
    26941 ataatataaa ctaaatttta taggaggaag acaatggatt ggtacgatta tatgatacag
    27001 gcatccaaac aatcacaatt caacgcaagc cattggtttc gctatttgcg aaaagttatt
    27061 tttgaagact attcttattt aacaaaccaa gatgtagaaa agttgctaga ctccaaagaa
    27121 ctaacccgtt ttcaaaaaat tagcttgaag tatgcctttc aagagcatac tccaactcat
    27181 aaatatgtga tttcattaaa taaacctgct aagttaacca atgttcaaaa attgatggag
    27241 aaatacaaac atggataaaa tgaaaccggt cttccaagcc ctaaataaga aattaattca
    27301 ggaaaatctg actttaacaa ttatggttat gtcttagaat atcatggttt acgtgccaca
    27361 caagatgttg atgcttttta tgaccaaaat cagaaaatca atgaaattat tgctcgtgta
    27421 ggaaaacagt ttaatcttaa catccacgaa gagttatggc tcaacaatca tgttgcaaag
    27481 caaatatgaa caaacaacct cccttaagtt tatgcgaatc cttgtactca tttgagaatc
    27541 tgaccgtttt agtagtccct attgagtatg tgttaggaat gaagatgatg agtatcagag
    27601 agcaggattt gaaagatatt ggtgcaatta ttaaatacaa aaactttcat tcaccattcg
    27661 atacctttaa atatttaaaa gacatgggat ttgatactat tgacctctct gttctattag
    27721 aaggttttag ttatgcttat ggtatggatt ggttagaaaa attttttaaa gaaaatcaag
    27781 ataaacttcg cgaattttat taacagtatc aaacaagatg attgtcaatt agccagtcgt
    27841 cttattttta tgatggaatg aaataaaatc ggaacaaatc acttagagaa ttccagtcaa
    27901 tttctagcgc tgtttgagac gtttcagtgg actatagtaa aatgaaataa gaataggaca
    27961 aatcgatcag gacagtcaaa tcgatttcta agaatgtttt agaagtaaag gtgtactatt
    28021 ctagtttcaa tctattatat ttcagattcg gtccactatt ccttcccaaa aacattgcat
    28081 attgcgccga aggaattgct cacactatcc caagcacaaa accctcagtc gtttgaccga
    28141 gggttccttt ttattattca agaacttgat tagctcaatg catccaaggc gtcatccatt
    28201 gaaagaactt cgtggaagac acgttgtgtc aattcagttt tttgttctgg agtgaggtat
    28261 ttagtgttta cacagtatcc agagatacgt acgataacgt cttcgcctga catgattttt
    28321 tcgtaaacat cgttcaagtc cataacgttc aagttaacgt gttgtccacc gttttcgaag
    28381 taaccatcaa ggattgttac caagttatca acttgttcat cacgagtctt accaagagca
    28441 cgaggtgata cttgtgtagt caatgagata ccgtcagctg cataactaaa gtcaaggcta
    28501 gaaagtgagt tcaagttttg caaccaacca cctttagctt tgttagatgg gttagcacct
    28561 ggtgagaaga attcaagttt agacaagttc acagaaccat cttcgttgag gtatacacct
    28621 ttgtgaactg gtgagttacc agtttgttta gagtaagcaa cgttagatgt gattgtcaaa
    28681 agtgatactg tagcttctgc gtctttgtat agtttgtgac tacgtagacg agttgtgtaa
    28741 gcttcgatca accattctgc caattcgttt gaacgtgggt catcttcacc ccagcgtggg
    28801 tagtcaccga ttgtttcgta atcgtagatg tagccatctt cgtcacggat tggtttaact
    28861 gtagcgtatt tgatagctga caatgtatca acagtgttag caaatccaca gataccgaat
    28921 cccatgttgg cacgttgttt agttggcaag aaggccattt gaacagcttc gtagttgtac
    28981 ctatcagtca tgtagtggat gatgttcaag gcatctacgt aagtgtcagt caaccagtca
    29041 agagattttt caaagttcgc tttaactgat tcgaattcaa gaacttcgtc acggattggt
    29101 tcgatatcaa atactttgta gtctttgtga acatcgtcgt aaccaccatt caaaccagta
    29161 agaagggctt taagaacgtt tacacgagca ccgaagtact ggatgttgtg gcgttgttct
    29221 tcattttctg gatcaagtgg agacacacag catgagatac agctcatttc accatatccg
    29281 tctttagcca ttgttgttac accttcgtat tggatagaag agtgtttgtg gctcatgtgc
    29341 atacagtagc gacggaagtt gtatggcaat ttgtcagtcc aaagaactgt caagtttggt
    29401 tctggtgagt taccgatgtt gtcaagagtg ttcaagaaac ggtagtccat cttagtaaca
    29461 cggtgacgac cgtcgttacc cataccagcc atagaagttg tgataaaggt tgggtcacct
    29521 gagtacaatt ggtcataagc ttttgtacga gcaaatttaa ctgtacgaag tttcataacg
    29581 aaatcatcaa cgaattcttg gatttctgat tcagtaaatg taccacgagc aaggtcacgt
    29641 tctgcaaaga tgtccaatac gattggtaca cgacctagag atgtagcagc accgttaatc
    29701 acacggcaga cagccatgaa agcaatgtta acccattgga ttgcttcttt cacgttcatc
    29761 gctggtttgc gaacatcaac cccgtaaagg tcacccaggc gaacaacttg ttgcaatgct
    29821 tggtattgaa ggtttacttc ttcacgaaga cggattgttt cttcatcgat ttctttgatt
    29881 gcattccagt cgtttacttt ttcttgcatc aagtagtctg caccgtaaag agcaagacgt
    29941 gcgtaaacac cgatgatacg tccgcgtgag tatgcatctg gaagaccagt tacagtgtgt
    30001 gcgtgacgag cgcgacgaat atttgaagtg taggcacgga aaataccgtc gttaactgtt
    30061 gttacatatt tagtgaagat ttcgtgaaca gctgggtctg gttcgtatcc attttctttc
    30121 aaagtagttt cagccatacg gataccacct tttggcatga agttcaattt gaagagttca
    30181 tcgttttgga taccgaagat aacttcattt tctttgtcga taaatccagc agggatatca
    30241 gcgatagatg ttggacgagt gtccattggg aaacgagttt cttcgtagtg tgctttagtt
    30301 tcttctacaa ttttcttgat gtgaagtgaa cgctctgttg gtcctgcaag gaagctttcg
    30361 tctccatcat aaggtgtgta gttagcttgt acaaatcgtg atacacttgc tttttctttc
    30421 caatctacgc ctttgaagcc ttcccaagct ttgtcaaaaa tatcttgtgc ttcaacaact
    30481 gtcttaacaa ccatattaat gtcctctttt ttctagtaac agtcatctgt tacattcata
    30541 agacaagtat accatatagt aaccgatttc aacaagtgaa aattccctat ttttacactt
    30601 tcttttctaa aacagtctat attttatttc aaactgtatt atatttttga aaaaataaag
    30661 tccttttttc tttttttcag aaaaaagggt ataataaaag aaaataagca gtaacactca
    30721 atggaaatcg aaaagcaaac taggaagcta gccgcagatt gctcaaaaca ctgttttgag
    30781 gttgcagata gagctgacgt ggtttgaaga gattttcgaa gagtataaaa aggtgctagg
    30841 catgttgatt tttcctttgt taaatgattt gtcaagaaaa atcatccata ttgacatgga
    30901 tgcctttttt gctgcagtgg aaatcaggga taatcctaaa ctcagaggaa aacctgtcat
    30961 tattggaagc gaccctcggc aaacaggtgg acggggagtc gtttctacct gtagttatga
    31021 ggcaagagct tttggtgtcc attctgccat gagttccaag gaagcttatg aacgttgtcc
    31081 ccaggctgtc tttatctcag ggaattatga gaaatacaag tctgtgggac tccagattcg
    31141 agctattttt aagcgctata cagatttgat tgaacccatg agcattgacg aagcctattt
    31201 ggatgtgaca gaaaataaac tcggtatcaa gtcagcggtc aaaattgctc gcctcattca
    31261 aaaagatatc tggcaagaac tccatctaac tgcttccgca ggcgtttctt acaacaaatt
    31321 cttagctaaa atggcgagtg attatcaaaa accacatggt ttgacagtga ttctacctga
    31381 acaggctgag gattttctca aacaaatgga tatttccaaa tttcatggag taggaaaaaa
    31441 gacagtagaa cgtcttcatc aaatgggcgt ttttactggt gctgatttac ttgaagttcc
    31501 tgaggtaacc ctaatagacc gttttggtag actaggctat gatctgtatc gaaaggctcg
    31561 tggcattcac aactctccag tcaaatccaa tcgcatccgt aaatcaatcg gcaaggagaa
    31621 aacctacggg aagattctcc ttgctgagga agatatcaaa aaagagctga ctcttctatc
    31681 agaaaaagtc gctctcaatc tacatcaaca agaaaaagct ggaaaaattg tcattttgaa
    31741 aatccgctac gaggactttt caactcttac caaacgaaaa agtcttgctc aaaaaacaca
    31801 agatgctagt cagataagcc aaatagccct gcaactctat gaagaattaa gcaagaaaga
    31861 aagaggtgtc cgcctattgg ggattaccat gactggattt taaagctcaa tgaaaatcaa
    31921 agagcaaact aggaggctag ccgcaggctg ctcaaaacac tgttttgagg ttgcagataa
    31981 agctgacgcg gtttgaagag attttcgaag agtataaaac cttgaagagt tgccccttca
    32041 aggtttttct tatacaaata aacggacaaa actgtaaagt agcaaaacac taccaagcac
    32101 gatacggtat ttaccaaaaa gggtgaagtc gtgttttttc acatagctgg tcaagaagcg
    32161 aatagccacc atgctgaccg caaaagctac tcccatcgcg accaagagta aaaacaattg
    32221 cccaaagctc aagagttctc cggctttcac aaatttgaaa atctttaagg cactagctcc
    32281 aaacataacg ggaatcccaa gatagaaggt aaattctgtc acaactgaac gactggttcc
    32341 atttaacaaa ccaccgacaa tcgttgcacc tgaacggcta gtccctggta aaagagcaag
    32401 aacttggaag agtccgatat agaaagcggt cgtataagga agcttgtcca actctgttac
    32461 acttggctcg atagcacgcg ctttattgcg cttttccaaa tatatgaagg caaccccgta
    32521 gataatcaac atgagagcaa ctgaaaccat gttatggaag tgggtatcaa accaatcatc
    32581 aaatttaaag acaccaagta aaggtaaagt agcaatcaag accttcaacc atagtctcca
    32641 agtcttacga acttcctgtt tgtccttagt cggtttaaaa ggattgagct tgttaaaata
    32701 aatcaccata actgctaaaa tagcaccaag ctgaatcacg acattaaaca tggacataaa
    32761 ggcttcattt tgattttggt attggataaa ctcctctgct aaaatcaagt gacctgtact
    32821 ggaaatcggc aaccattccg taattccttc aacaatcccg aagaagatag attttaaaat
    32881 ttcaataaga tacatatatt tctccttata ttatatttaa cgcagttagc tactgccaaa
    32941 gcccaagtgg tatacttgga ataagccact gtggattagt tcatttcctc caatcgcttg
    33001 acgatttccg aaagggtcta acaacagctt tttgtttcaa ttggtaatga gtttgataac
    33061 gcatagacgt tttatctcgt ctatggtaac aaggcaaaaa gttcgtggat aaccaagtag
    33121 acttgaaata ctatatctgg aggtactccc atgctttatg tgggcattga tgtcgctaaa
    33181 aataaacacg atgttacagc cttgaatgtt cgaggaaaac tgttcttaaa ccactcactt
    33241 tttcaaataa taaagctggt tttgaactct tagatctgtc ttttcgacag ctcaaccaag
    33301 actgtctcat cgctcttaaa cttctttctg accccaatcg tgaacaattt caacacgata
    33361 atcggcaaat agaactaaaa atactggcta gacatattca tcgtctcaag aaaaaacagt
    33421 ctgattggaa agtacaatac actcgttgtc ttgatatcat ctttcctgag ttggataaaa
    33481 tcgttggaaa gcattcagaa tatacctacc aactcttgac acgctaccct aatcctcaga
    33541 aaaggcttga ggcaggattt gataagctga tagaaattaa gcgattgacc gcttctaaaa
    33601 ttcaggatat cctctcagtc gcacctcgtt ctatcggaac aacatctcct gctcgtgaat
    33661 tcgaaatcat cgaaatcatc aaacattaca agaggctcat tgacaaggcg gaaacatgtg
    33721 tcaatgactt gatggctgag ttcaactcgg tcatcacgac ggttactggg attgggggtc
    33781 gtttaggggc ggtcatttta gccgagattc gaaatattca tgcctttgat aatcctgctc
    33841 aattacaagc tttcgctgga ctggattctt ctatttatca gtcaggtcag attgatttag
    33901 ctggaagaat gatcaaacgg ggttcccctc atctgcggtg ggcactcata caagctgcca
    33961 aagcatgcgc tcgcttttca cctgctttta aggcctatct taagactaag ttagaataag
    34021 gaaaacatta caatgtagcc atcatccacc ttgcaaaaaa acttatccga accctgtttt
    34081 atatcctaaa aaagagctgc catttgacga acaaaaagtg atgtaatttc tgaaattaac
    34141 acaggattac ctttgaaaaa atggactttt tcaagggctt tttgccgtgc tctaaaatca
    34201 tcgccaaatc atcaaattga aataagaaat agtttagata aaactattga cttttcttat
    34261 agtttgtctt tcttctatct tccattatat catacttttt cagtctatgg tagctctctt
    34321 taaaaggctc cgatactgcc gccacctccg cctccagaga agccaccacc agaacttcca
    34381 cttccagaag atacagagta ggtacttgct gtatttgcga cactagcata atggctcatt
    34441 tgcgcgcttg aatgataaaa catactgtgc cagccataag ctacatagag attgatatct
    34501 ggattttcaa cttgaatctg atgaaccttc atcaaatgac taaccttgtc cgcatagcca
    34561 aataaggttg catagaccaa gagacgattc caaacaacaa tactttccaa ttcagcctta
    34621 tccagtcgtg caatctcacg taacatattt tcaaaactgg tccagagata gtagacctca
    34681 gctcccgctt catttagaac accatcacga ttatctagtc gaagcttcca ataatagaaa
    34741 acagacaaaa ctaaccctag aaaaccaagt attggcaaag ggaggtaaag atagccatga
    34801 acgtctaaac tgtacaagaa caaaccaaat ccgataaata ggggcaagat agtcaagaca
    34861 cccataccca cttgcaaagc cttttccaaa ccagttaaag gacgatagta atctgggagt
    34921 ccccagaaga caactcgctt tctcactcct tcttgcatct cttttaatac tgcttcgaaa
    34981 gaagatttga gctgaatccc tcttgcttga atccgtttct catcagcagc tttagctccg
    35041 cgataaaggc tgtcagatac cttgtaatcc gcaaacaaat tggaaagagt ggcttctttt
    35101 ttgcctgaaa aggctagatt tagacagtct ctctcaaatc ttgacaaacc atcttctttc
    35161 accaatctca agccaactgc atctccttct gaaataatag aaacattccc acggtccatc
    35221 acatctagca aggtagcttg aataagttgg tcaaaagtga atttgccagc ccccttgact
    35281 aagggactca cttcctccaa ggaggtcgag tagacagcct ctgataaaac cataggctct
    35341 aattccattg gtggttcata gagacgatga tttttggcat atttgactga aggagtggtc
    35401 tttcttctat aaataaaata gaagcagaca ctcaataaca aggagataga aaggatcgaa
    35461 gggaggaccc aagtaacaag ttgtttactc tgatcttttt ctctaacaat cgagtcttct
    35521 atcttattaa actcttctaa acgattccct ttcaatccct gatccctagc gctagcaaaa
    35581 tcggtccgag gccagtaggc atgcaactca actccacgct tagccggaag attgtctaaa
    35641 cggatagtat aatcaaggtt actcttttca atcgttccct ctctaaaaag tttccctgta
    35701 tggaaaaaga gtttttcagc ccccttgtct ccccttacat gaaattcaaa cttttcaata
    35761 gactctgaac tatctgtcag aggttgccaa tttaattcag cgatatcatc ataaaggaaa
    35821 agtaaatttt ttaagttcca gacgaggtca acttcaacta tgtcgccctc ctgacctgga
    35881 ttatagactc tcacagtata accatccgct tcttctgtta cttcgctagt cacatctgct
    35941 agttctgcac cgtttttcgc ggcctgaacc tttggatgag ggtcaatgtc aaacccgcta
    36001 ggcatcttac cagcacgtcc aagtcccacg atttgtccct taaagtcctc ctcaaactgg
    36061 taaactatct tctgtctaaa ctctgccgta ttatctgcat gaatatacaa atccccttga
    36121 taagagttta tcttgaaatc aatggcaaaa acagagagtg gaagaaggca aaacaagcct
    36181 aacaccagta agaaaaaagt ttttttcatc aactaagccc cctttttatc tttcttatca
    36241 ttatagcatt ttttcgtaag taaaggctta cttatgttga aaaattacgc atttttcgat
    36301 aaaataggag acagttattt tttaatagat cagaatagga gaaatcatga gaaaaatata
    36361 cttatctatt ttcacaagtc tcttgctgat gctaggactt gtcaatgttg ctcaagccga
    36421 tgaatattta cgcatcggga tggaagcagc atatgctccc tttaactgga cccaggatga
    36481 tgatagcaac ggagctgtca aaatcgatgg gaccaatcag tatgccaacg gatacgatgt
    36541 tcaaatcgcc aagaaaatcg ctaaggactt aggtaaagaa cctttggttg ttaaaaccaa
    36601 gtgggaaggt ctagtccctg cccttacttc tggtaagatt gacatgatta tcgcaggtat
    36661 gagtccaact gcagaacgca aacaagaaat tgccttttcg agcagttact acactagcga
    36721 accagttttg cttgtcaaaa aagattctgc ctacgcaagt gctaaatctt tggatgactt
    36781 taatggtgcg aaaatcactt ctcaacaagg tgtctacctc tacgacttga ttgcacaaat
    36841 cccaggtgct aaaaaagaaa cagccatggg agacttcgct caaatgcgcc aagctcttga
    36901 ggctggtgtc attgatgctt atgtttctga acgtccagaa gcactgactg ctgaagctgc
    36961 gaactctaag ttcaagatga ttcaagtaga acctggtttc aaaactgggg aagaagatac
    37021 agctatcgct atcgggcttc gtaaaaatga caatcgtatt agccaaatca atgccagcat
    37081 tgaaaccatt tcaaaagatg accaagttgc cttgatggat cgtatgatca aggaacaacc
    37141 tgccgaagct acaacaactg aagagactag cagtagtttc tttagccaag tcgctaaaat
    37201 tctttctgaa aactggcaac aactcttgcg tggtgctggt atcactcttt taatctctat
    37261 cgtcggaacc atcataggtc tcattattgg acttgccatt ggtgtcttcc gtactgctcc
    37321 tctctctgaa aacaaagcca tttatggcct tcaaaaacta gtcggctggg ttctcaatgt
    37381 ctacattgaa attttccgtg gtacgccaat gattgttcaa tcgatggtta tctactatgg
    37441 aactgcccaa gctttcggga tcaaccttga ccgtacactg gctgctatct tcatcgtttc
    37501 aatcaatacc ggtgcctaca tgactgaaat cgtccgtggt ggtatcctag cagttgacaa
    37561 gggacaattt gaagctgcga ctgctcttgg tatgacccat aaccagacca tgcgtaagat
    37621 tgtcctacct caggtagtcc gtaacatcct acctgcaact ggtaatgaat ttgtcatcaa
    37681 tatcaaagat acatctgtat tgaacgttat ctctgttgtc gaactttatt tctcaggaaa
    37741 taccgtggca acacaaacct atcaatactt ccagacattt acaatcatcg ccgtgattta
    37801 ctttgtcctc accttcaccg taacacgtat cctacgattt atcgagcgcc gaatggacat
    37861 ggatacctat actacaggtg ctaaccaaat gcaaacggag gatttgaaat aatgacacaa
    37921 gcaatccttg aaattaaaca cctcaaaaaa tcctatggac aaaacgaagt gctaaaagac
    37981 atttcactca ctgtccacaa gggagaggtc atctctatca tcggaagctc tggaagcgga
    38041 aaatcgacct tcctacgctc cattaaccta cttgaaacac caactgatgg acaaatcctt
    38101 tatcatggac aaaacgtcct cgaaaaaggc tatgacctca cgcaataccg tgaaaagttg
    38161 gggatggttt tccaatcctt taacctcttt gaaaatctca atgttcttga aaacacaatc
    38221 gtcgctcaga caactgtcct aaaacgcgaa cgcacagaag ctgaaaagat tgccaaagaa
    38281 aacctggaaa aggtcggcat gggagaacgc tactggcaag ccaaaccaaa acaactctca
    38341 ggtggtcaaa aacaacgtgt ggccatcgct cgtgccctct ccatgaatcc ggacgctatt
    38401 ctctttgatg aaccaacatc agctctcgat ccagaaatgg ttggagaagt cctcaaaatc
    38461 atgcaggacc tggctcagga aggcttgacc atgattgtcg taacccatga aatggaattt
    38521 gcccgtgatg tctctcaccg tgttatcttt atggataagg gcgtgatcgc tgaagaaggt
    38581 aaaccagaag acctcttcac caatcctaaa gaagaccgaa caaaagagtt ccttcaacgc
    38641 tatctcaaat aaaaagaaaa ggctgcatca accgtgcagt ctttttgctg tcctcaaaat
    38701 gaaaaggcag attctctatc tctactactt gaaggtcaag aatccgccgt tatccaaaga
    38761 ttaatcttca aatttttcat aatttttttc atagaaatca attaggccta gggctgtttc
    38821 aaatgaaata ttttttactt ttgcacgacc ctgcgccaga gcaatgatag acatttcacg
    38881 cgcattcgtt tctttagaga tacggtagcc tgtgattttc ttatcacgaa cccagccaac
    38941 aactgattct actttttcaa agtttgactt agccatgttt ttctcctatt ttcttcttta
    39001 taatatttaa ttgtatacgt ttttactact tttgtcaata aaaaaaacat atattcaacg
    39061 aaaataatta gttcagaatt ttcttacttc ctttttaaat ccgataatat ataggttttg
    39121 ctagcctcta caccataaat atttgctaat aaaactactg tattattacc ctcttaaggt
    39181 gcgaaattat tcaagttctt aaaaaatgct tctctatttc cgtaagatag cttatttctt
    39241 cgatttaaga actgaagatg atagttctaa cctttagaaa tccaagcctt cactagctca
    39301 aaaactccta tctttcttcc tcaataaatc atctgagaga taggtattcc ttatatcctt
    39361 caaattcatc actcctttgg atattgaggt gctagcctag aagcagacac ccgattatct
    39421 aaaccatcct taatagagat gacaagacag ataagctcag ttaattactt atatatcttt
    39481 ttaatatggt atatttgtca acaaaaagaa atcaaatcat accttatact caatgaaaat
    39541 caaagagcaa actaggaagc tagccgcaag ttgctcaaaa cactgttttg aggttgcaga
    39601 tagagctaac gtggtttgaa gagattttcg aagagtatta aagacagtgt gactatgctt
    39661 gtcaatagat aggaaatcaa aatgaaggat ggaaatctga gccaaacatc ataagtgcta
    39721 taatgaacag aagtaagaat tgcacgataa gttttctaaa accataggaa tcgtcccctt
    39781 tcttcatctt cattatagca catatacatc agttgtacaa ataatatgat atttttttat
    39841 tagtcctcag acaagcatat tataaagcgt ttcattacca tttaagttaa tataagctgg
    39901 atcaaaacct tccattctac gaatcaaacc tgcataatca tgcttatctg ctaaagcgat
    39961 cccaattaat actgggcctg ttcccttgct agctcgtttg atatactcaa aacgtgtgat
    40021 atcatcattt ggccccagga tatcatttac aaactcacgc aaagctcctg gacgttgtgg
    40081 gaaattgacc acaaagtaat gtttgatacc atcataaatc aaggcacgct cttccatttc
    40141 tggcatacgg ttgatatcat tatttcctcc agaaatgata caacaaatgg ttttcccctt
    40201 aatatattca gctaaaacct ctaaagaggc gatactagcc gctccagcag gttctgcgac
    40261 tatcccttgc ttagagtaaa ggtcaatcaa ggtttcagaa atcaatccct catcgacacc
    40321 taccaaagtt ttaatatgtt gacgagttgc ttcataggtc aactgaccta ccttttgcac
    40381 agcaatccca tccgcaaatt tatcaatttc cttgagtttg actggacctc cagcctcaaa
    40441 ggcagctttc atggaacgcg ctccattcgc ctctactccg ataacctcaa tctctggact
    40501 tgtttccttg atataggtag aaaccccggc aatgagaccg ccaccaccaa caggaaccaa
    40561 gacagcatca aaatcaatcg attcttttcg agcttcttct aaaatctcat aagcaactgt
    40621 tccttgacct gcttgaacat gagcatcatc aaaaggatca ataaaggtac gattttcaga
    40681 gactgtaaat tcttgagctg ctttggctga ggcatcaaag gtatctccaa ctagtttaat
    40741 agttacaaaa tccccaccaa aaaagcgaac ctgaccaatc ttttgttgtg gcgtagtaat
    40801 gggcataaag atagtagcag gaattttcat ttcattacaa gtataggcta ctccctgcgc
    40861 atgatttccc gcagaagcgc aaactacccc acgttcacgt tcttccttgc tgagctggga
    40921 aatggcataa taggcaccac gaattttaaa ggagcgaaca cgctgggcat tttctttttt
    40981 caaataaatc ttagcaccat acttctccga taaataatga tcgtaatcca gtggagtatt
    41041 cacaaccaca ccgttcaaga ccttgtgagc cttgattata tcttttgaac ttaacatata
    41101 aaacctcttt ttctataaaa aacagtcact aatgactgtt ttttagttat tcatctccga
    41161 aaatttcagt aacactttca tggtatttat gagccatacg aatcgaaaac tctttaggaa
    41221 gttcataacg atttgtggaa atccaatcat ataaccattc taccaaactt tcttcactat
    41281 cattacgatg gaagataaaa tagtttaaaa tttctttata ttctacatca ttcaaatcca
    41341 acgtgtctac aaattgacta cgaggaacaa aattagaatc taattttctt agttgatctg
    41401 tcaattctcc caattgtaaa tccaactgaa aaaatagttt ttgcagttgc ctatcagttt
    41461 catcacatcc tgtcttgata gaaaacaaat tggtaatatt catatgattt caacccctaa
    41521 ataagtacat ctaatatccc acgaatagct gaagctaaag ttttcgcagt ccagtcattt
    41581 aaacccgatt ctttcaatcc agatgcaata atttgctcta tttgatataa accgccatct
    41641 atcgtctcat ttattctgcg aagaggacct tcaatatagg ataaagcttc tccgaatcta
    41701 acagctgatt taggtcctaa tgatttacca actatatttg ttaatatttt ttatttctca
    41761 aaatccattt cgctatataa cgagcagatt tagtcgcacc agctctctca aacggagaat
    41821 gaatttcaag accttcttct ctagctattt gtgccaattt gaagaattgt tcaaaggtca
    41881 tatgcaacct accatcttca aaattagcat catcataaat gttaattaca gcattttcat
    41941 catacgacca atctgcttta ttttggtctg ctagcactat taccgacggt gtaattacat
    42001 tatacaacta gaaccaataa taacgatgca atttttctca taatcttttt cataaaatca
    42061 tctccagcgc tatatatttc taattagtta tagattttga atgcatcatc gtcgttttta
    42121 ccaacgaatg gcattgcttt acgcaattct gcaccaactt tttcaatttc aaggttagct
    42181 gcttgttcac ggtaagcagt caattttgga cgtccagctt tatagtcatt tacaaagtca
    42241 tttgcaaatt taccattttg gatgtctgcc aagacagcct tcatattttc tttaacttgt
    42301 tcagtgatta cacgtggacc tgatacatag tcaccgtatt cagcagtgtt tgaaatagat
    42361 tgacgcattt tcttgaatcc accttcgtag atcaagtcaa cgatcaattt catttcgtga
    42421 agaacttcaa agtaagccaa ttctggagcg taacctgctt ctgtcaagac ttcgaaacct
    42481 gcttcgataa gggcagtcaa accaccacaa agtacagctt gttcaccaaa caaatcttct
    42541 tcagtttctt ctttgtaagt tgtttcaaga agacctacac gagccgctcc aacaccttta
    42601 caccagtcca tagcaatgtt tttagcattt cctgttgcat cttggtatac tgcataaaga
    42661 gctggaacac caaatccttc ttcgtaagta cgacgtacca agtgtcctgg tcctttagga
    42721 gcacacatga agacatctac atccgcagga actttgataa attcaaagtg gatgttgaaa
    42781 ccatgggcaa atccaactgc gtttccagct tccaagtttg gagcgatttc tgcttcgtac
    42841 aattcttgtt gaatttcgtc tggcgccaag atcatgataa catcagccaa cttagtagct
    42901 tctgctactg tgtaagtatc aaatccatct tcttttgctt tatcaaaaga tttacctgga
    42961 cgtacaccga taataacgtc acgacctgaa tcacgcaagt tttgagcatg cgcatgccct
    43021 tgtgaaccat aaccgataac ggcgattttt ttaccgtcaa gtgctgctac tttaacatct
    43081 ttttcatatt ccatttgaac tgtcatagct tttctctctt ttctattatt tattgccttt
    43141 taagctggtt taacaaattt aagttggatt tttaatcgcg ggtaaatcca gttgcacccg
    43201 ttcgagcaat attgcgaata ccgtatgggc gaatgactcg caatagggct tcgctctttt
    43261 ctgcatttcc cgtcatctga atggtaatcg agcttggcgc tacgtctacc actgttgcac
    43321 ggaaaggttg aataatcgct aaaatctcag ctctcttctc agctggcgct gacatcttaa
    43381 ccaaaatcac ctcgcgctcc aaatgaggct tgtctgtaat atctcgaatg cgaatcacat
    43441 caatctgacg attgagctgt ttgatgattt gctccacttc atcatgagaa gcaacatcaa
    43501 taataatagt gatacgcgat acattcggat cttctgttgc tccaacagag atgctttcaa
    43561 tattaacctg acgacgagat aggacacctg taaagcgatt gaggactcct gaacgatttt
    43621 gtagttttgc tgttaacatt ctacgcatgg aactgcaccc ccaacatctc atgattactc
    43681 ttaccagccg gtaccattgg taacacctgt tccttacgag aaatatctac ctcaattagc
    43741 ataggaacat cctcagtgat gacttcaagg tcttgagcca aggtctcagg attgtcaaac
    43801 ttatagtttt taataccata agcctgcgcc atcaattgga aatcaggaag ggtatcaaag
    43861 accgactctg atgttctgcc ttcatagaag gattcctgcc actggcgaac cattccgagt
    43921 gaatgattgt tcagcataac caccttgatt ggcaccttgt aaatattcaa aatagccaac
    43981 tcctggttgg tcatttggaa accaccatcc ccaacaaaca agactacttc cttatctggg
    44041 ttagcaattt tagcaccgat tgctgctgga attccaaagc ccattgttcc caaaccacct
    44101 gaagtcacta actgacgttc attttggtag ggataatact gagctgtcca catttggtgt
    44161 tgaccaacgt ctgttaccac aatggcatct ccattcgtca attcaccaat tcgttcaata
    44221 actgcttgcg gttgaaccac acgctctttc ttgtcatacg aacgaacacg attcttgtct
    44281 ttagtgactt tctcaatcca cttttcagta ttgttgtgaa ctgttggttc tgctagcaac
    44341 atttgcaagg ccttcttagc atctccaact acaggaatgt ctgcactgat aatcttgcca
    44401 atctcagctg ggtcaatatc aatgtgggca accttagcat tcttagcgaa agtcttagga
    44461 ttccccgtca aacggtcatc gaaacgagaa ccaatactaa tcataaagtc cgcttccgtc
    44521 atggcaatat ttgctgcgaa tgacccgtgc atgcctccca ttccaagaaa gagtgggtga
    44581 ctcgttgcaa tcgttccttg tcccaaaaga ctggttacca ctggaatttg atagcgttct
    44641 gcaaattcat ttagttccgt agcagcctca gcataactaa ttccaccacc agctaacaag
    44701 actggctttt tagccttgga caattgcttc aagattttct tgatttgcat atcattcggc
    44761 tcaagagtcg gctgataact tggtaaattc acttctggtg aataaatgaa gtctgtttct
    44821 aaagcagata tgtcttttgg taggtcaatt acaactggcc ctggacggcc tgtagttgcg
    44881 atatggacag cttccgtaat gatacgcgga atatcagctg tctcacgaac ttggtaattg
    44941 tacttagtga ttggcatggt aattcctacg atgtctgcct cctgaaaggc atccttccca
    45001 atccctgctc gcgccacctg acctgtaaag accaaaaggg gaacgctatc gctcatagca
    45061 tccgcaatcc ctgtaatggc atttgttgct cctggtccac tagtgacgac ggcaacaccc
    45121 aactttccag ttgatttggc atagccttca gcttcatgca aacaaccttg ctcatggcgc
    45181 cctagaatgt ggcgaatgcc tttaaaatta tatatcgcat cataaaaagg caaaaccgca
    45241 ccaccaggat aaccaaagat ggtatcaact cctaaatcac gaagtgtttc caaaactagg
    45301 tccgaccccg tcttaggaga ttctaaactg attttctcca ttattcccct ttctttcctc
    45361 ttaaaaataa cttgttacta tcataccatt ttttcaaaat ttttcaagat aaaagaagaa
    45421 attttctgaa ttttctattt taacgtttat ttatgaatgt tatttttgtt tttattaaaa
    45481 agataccgat ttcatttact aaaaagaaaa aagaactgat ttctcagtcc ttcattaatc
    45541 ttattccaca ctaaataggt atgggtaaac aggttgttga ccttggtgaa tctcgacttc
    45601 aacgtcttcg aattcttcta cgatttcttg agcgatttca ttggcaagtt cttcgcttcc
    45661 gtcttcaccg acatagaagg ttacgatttc actgtcttca tccaacatat gtttcaaggt
    45721 ttcagtcaat gtttggtgca tatcagggtt tgacacaaga atttttccat ccaccatacc
    45781 taaattatcg ttttcatgga tttctaagcc atcgatcgtt gtatcacgca cggctgttgt
    45841 gacgcttccg ctaacgacat cgctaagagc agctgtcata cgctcttggt tttcttcaat
    45901 ggacttgctt ggatcaaagg caagaagact tgtcatacct tgaggaagag tgcgagcctc
    45961 taccactacc gctggttgct ccaaaacttc tgccgcagat tgagctgcca tgaagatgtt
    46021 cttgttgttt ggcaagaaga tgatgttacg ggcattaacc tgttcaacag ccttgataaa
    46081 gtcttctgtt gaagggttca tggtttgacc gccttcgata acataatcca cgccttgaga
    46141 acagaagata tctgctagac ctttaccagc caccacagca atcaaagcat actctttttc
    46201 ttcagccgac ttgataactt gagtagcttc tttctcaacc tgtgcttcgt gttggttacg
    46261 catattgtca acttttacct tgaccaagct accatatttg agaccttctt gcataacaag
    46321 tcctggatct tctgtatgaa catggacttt gacaatttca tcatcgttaa caacgaggag
    46381 agaatctcca agctcatcca agtagttacg gaattcatcg tagtcaaaat ctttagcata
    46441 ggttggacct tgcttaagag ctaccatgat ttcagtacag taaccaaacg tgatgtcctc
    46501 agtcgctacg tgaccagcta cagacttatg atgctctaca ttgatcatct cactcatgtt
    46561 ggcaggagtc gctacaaagt cctcagatgc aatatattcg ccagtaaggg ctgaaaggaa
    46621 accttcgtag atgaagacca atccttgacc acctgagtcc acaacgccaa cttctttcaa
    46681 tactggaagc atgtctggtg ttttagctag agctgtttta gcaccttcca aggctgcgcg
    46741 catgacttca acagtgtcat ctgtttgctc agcttttttc ttagcaccga tagcagctcc
    46801 acgagaaact gtcaaaatcg ttccttcaac aggtttcatc actgccttat aggcaacttc
    46861 cacacctgat tggaaggcca gagccaagtc ttgacctgtt aactcgtctt tatccttgat
    46921 agcttgggaa aatccacgga aaagctgaga cgtaatcact cctgagttcc cacgcgcacc
    46981 catcaaaagc cctttggcaa gaatgctcgc tacttctcca actgtagaag ctggcttgtc
    47041 tgcaacttct ttagcaccat tttcaatggt cattcccata tttgtcccag tatctccatc
    47101 tggaactgga aagacgttta atgaattgac atattcagct tgcttattca agcgagttga
    47161 tgcagcctgc accatttctt gaaataagct agtagtaatt tttgacacgg ttattctcct
    47221 acaactttga tattttgaat gtagacattt acagtctgag cagtaattcc aagctggttt
    47281 tccaagctaa aggcaacacg ctcttgaatg ttttttgaca cttcactaat ctttgttccg
    47341 tagcttaaca cggtatatac atcaactgca atactgccat cttcggctgc ctttacgacg
    47401 acacctttag aataattttc cttacctagc agggcttgga aattatcttt gagggcattt
    47461 ttactagcca taccgaccac accaaaaatc tcagttgctg ctccacctac gacggttgca
    47521 atcacttcat ctgttagttc gatttgacca tcttttgtat taatttttac agtcatcctt
    47581 tttacctcaa ctagttgata ctctatttta tcatatttca gcccaagtgt aaaagcagaa
    47641 tgatgtatca gcggatattt actctatttt tcaaacgatg ttatacccac aataaaagaa
    47701 aaaagaccct aaggtctcct ttgcttttat tattaaacgc gttcaacttt acctgatttc
    47761 aaagcacgag ctgaagccca aactttttta ggtttaccat cgataagaac agtaactttt
    47821 tgaaggtttg gttttacggc acgttttgtt tggttcatcg cgtgtgaacg gttgtttcct
    47881 gatacagtct tacgacctgt aaagtaacat actttagcca ttgtgttttc ctcctattag
    47941 atctaatata gcggatgtgc tagcaccaca taccgtacta tgttatcaca ctttcttatt
    48001 ttttgcaagg gaattggaag attttttatt tgtgtcttaa atcaggtctt gcgtgacatt
    48061 ttctgctctc cacatgccat tgttgattaa cagaatacca gaattaaaat tatgtgtata
    48121 aaaatcatct ctaactgcag ctaaggatat agccgtcaag tccaaatccc acagctcatc
    48181 tatcgatttt cttacaacaa tatctgaatc caaatacagt acacgagact cgcttacata
    48241 ctttggaata aaatacctaa aaaagccgca tatgaaagtc cctcaaaggg gagacgataa
    48301 cctttcagaa tactactgtc aatctaaaca ttcacaatct cactattcaa agtctctagt
    48361 cttttttcca ttaattggaa ccattctcgc ggaaggtcat cattaaaaac ataaaactta
    48421 agattataat gatgaacaca aagagatttt attgttgttt caactttatc catataagca
    48481 ttatctgcac ctaagacaat cgcttttttc tcttctttca ctttttatct catttctttt
    48541 attcccatca tatgtttcta cgtaaccatt attttcgcct attcgttcgt aaaaccatac
    48601 cagtggagat tttagatgaa gtcccattac ggtttacaat ttttacatta cgacacggag
    48661 tttggcaaat cgattctatt tgccaaacgt agttagtgag gcagttagct agttcgccaa
    48721 atagcgacta gcgtccaaca atttggaact ttagttccaa ttgttggtac tgagtcacat
    48781 cttctcctct aactctacgt ctggatactt gtccgcaaac cagcggaggg caaagtcatt
    48841 ttcaaagaga aagactggtt ggtcaaaacg gtctttggct aagatattgc gacttgacga
    48901 catccgttca tccaagtcct caggcttgat ccaacgaacg gtctttttac ccattgggtt
    48961 cataactact tctgcattgt actcgccttc catgcggtgt ttaaagactt caaactggag
    49021 ttgacctaca gcgcctagca tgtactcacc tgtttggtaa ttcttataaa gctgaacggc
    49081 tccttcttgc accaattgct caatcccctt gtggaaggat ttttgcttca taacattctt
    49141 agcagaaact ttcatgaaaa tttcaggagt aaaggttggc agtggttcaa attcaaactt
    49201 gtttttacca actgtcaagg tatccccaac ttgataagta ccggtatcgt aaaccccgat
    49261 aatatcacct gccacggcat tgatcacatt ctcacgactt tccgccataa actgagtaac
    49321 attagacagt ttagccccct taccagtacg agggagattg acactcatgc cgcgctcaaa
    49381 ttcgccagat acgatacgga caaaggcaat acggtcacgg tgacgagggt ccatgttggc
    49441 ttggatttta aagacaaatc ctgagaaatc cttgtcataa ggatccacaa tttcaccgtc
    49501 tgttttcttg tgaccatgtg gttctggagc aaacttgagg aaggtttcaa ggaaggtctg
    49561 cacaccaaag tttgtcaggg ctgaaccgaa aaagacaggc gtcaattctc cagccagaat
    49621 agcttcctct gaaaactcat tcccggcttc atttaaaagc tcaatatcat ccttgacttg
    49681 ctcgtagaaa ggattgctac caaaaagttt gtccccatct tctagactgg caaaacgctc
    49741 atccccttta taaagctcta aacgttggtt atagaggtca tacaagccct caaaggcttt
    49801 ccccatcccg ataggccagt tcatagggta gctagcaatg cccaagattt cttccaattc
    49861 ttgtaagaga tccaaaggct cacgaccgtc acggtccagc ttgttcataa aggtaaagac
    49921 tggaatgcca cgatgtttca caacctcaaa caatttcttg gtttgagcct cgatcccctt
    49981 ggcagagtcc acgaccatga ccgcagcatc caccgccatc aaggtacgat aggtatcttc
    50041 tgagaagtcc tcgtgccctg gcgtgtctaa gatattcacg cgcttgccgt cgtagtcaaa
    50101 ttgcataaca gatgaagtaa cagaaatccc acgttgcttc tcgatatcca tccagtcaga
    50161 tttagcaaaa gtccctgttt tcttcccttt taccgtacca gcctcacgaa tctcaccccc
    50221 aaagtagagt aactgctcag tgatggttgt tttccccgcg tccgggtggg agataatggc
    50281 aaaggtacga cgtttcttaa tttcttcttg aatattcata agttctcttt ctttgattct
    50341 ctatttttct tgtttcaata gctgagaatg atttttacat tggattttac cattcctttc
    50401 aacactccat tatatcggat tttagcattt ttttcaattt ctatttcttt tcacttcccc
    50461 ctcccttatt tataggaaaa tatggtaaaa tagaacagac taaaaatcat catttcacga
    50521 aaggatgcaa gatgaaaatt acgcaagaag aggtaacaca cgttgccaat ctttcaaaat
    50581 taagattctc tgaaaaagaa actgctgcct ttgcgaccac cttgtctaag attgttgaca
    50641 tggttgaatt gctgggcgaa gttgacacaa ctggtgtcgc acctactacg actatggctg
    50701 accgcaagac tgtactccgc cctgatgtgg ccgaagaagg aacagaccgt gatcgcttgt
    50761 ttaaaaacgt acctgaaaaa gacaactact atatcaaggt gccagctatc ctagacgatg
    50821 gaggagatgc ctaatgactt ttaacaataa aactattgaa gagttgcaca atctccttgt
    50881 ctctaaggaa atttctgcaa cagaattgac ccaagcaaca cttgaaaata tcaagtctcg
    50941 tgaggaagcc ctcaattcat ttgtcaccat cgctgaggag caagctcttg ttcaagctaa
    51001 agccattgat gaagctggaa ttgatgctga caatgtcctt tcaggaattc cacttgctgt
    51061 taaggataac atctctacag acggtattct cacaactgct gcctcaaaaa tgctctacaa
    51121 ctatgagcca atctttgatg cgacagctgt tgccaatgca aaaaccaagg gcatgattgt
    51181 cgttggaaag accaacatgg acgaatttgc tatgggtggt tcaggtgaaa cttcacacta
    51241 cggagcaact aaaaacgctt gggaccacag caaggttcct ggtgggtcat caagtggttc
    51301 tgccgcagct gtagcctcag gacaagttcg cttgtcactt ggttctgata ctggtggttc
    51361 catccgccaa cctgctgcct tcaacggaat cgttggtctc aaaccaacct acggaacagt
    51421 ttcacgtttc ggtctcattg cctttggtag ctcattagac cagattggac cttttgctcc
    51481 tactgttaag gaaaatgccc tcttgctcaa cgctattgcc agcgaagatg ctaaagactc
    51541 tacttctgct cctgtccgca tcgccgactt tacttcaaaa atcggccaag acatcaaggg
    51601 tatgaaaatc gctttgccta aggaatacct cggtgaagga attaacccag aggttaagga
    51661 aaccattcta aatgccgcta aacactttga aaaattgggt gctattgtcg aagaagtcag
    51721 ccttcctcac tctaaatacg gagttgccgt atactacatc atcgcttcat cagaagcttc
    51781 atcaaacttg caacgctttg acggtatccg ttacggctat cgcgcagaag atgcaaccaa
    51841 ccttgatgaa atctatgtaa acagccgaag ccaaggtttt ggtgaagaag tgaagcgccg
    51901 tatcatgctg ggtactttca gtctttcatc aggttactac gatgcctact ataagaaggc
    51961 tggacaggtc cgtacactta tcattcaaga tttcgaaaaa gtcttcgcgg attacgattt
    52021 gattttgggt ccaactgctc caagtgttgc ctatgacttg gattctctca accatgaccc
    52081 agttgccatg tacttagccg acctattgac catacctgta aacttggcag gactgcctgg
    52141 aatttcgatt cctgctggat tctctcaagg tctacctgtc ggtctgcaat tgattggtcc
    52201 caagcactct gaggaaacca tttaccaagt tgctgctgcc tttgaagcaa caacaggcta
    52261 ccacaaacaa caacccgtga tttttggagg tgacaactaa tgaactttga aacagtcatc
    52321 ggacttgaag tccacgtaga gctcaacacc aattcaaaaa tcttctcacc tacttctgcc
    52381 cacttcggaa atgatcaaaa tgccaacact aacgtgattg actggtcttt cccaggagtt
    52441 ctgccagttc tcaataaagg ggttgtcgat gccggaatca aggctgctct tgccctcaac
    52501 atggacatcc acaaaaagat gcactttgac cgcaagaact acttctaccc tgataatccc
    52561 aaagcctacc aaatttctca gtttgatgag ccaatcggtt ataacggctg gattgaagtc
    52621 gaactagaag acggtacgac caagaaaatc ggtatcgaac gtgcccacct agaggaagac
    52681 gctggtaaaa acacccatgg tacagatggc tactcttatg ttgacctcaa ccgccaaggg
    52741 gttcccttga ttgagattgt atctgaggca gatatgcgtt ctcctgaaga agcctatgct
    52801 tatctgacag ccctcaagga agttatccag tacgctggca tttctgacgt taagatggag
    52861 gaaggttcga tgcgtgtgga tgccaacatc tcccttcgtc cttatggtca agagaaattc
    52921 ggtaccaaga ctgaattgaa gaacctcaac tccttctcaa acgttcgtaa aggtcttgaa
    52981 tacgaagtcc aacgccaggc tgaaattctt cgctcaggtg gtcaaatccg ccaagaaaca
    53041 cgccgttacg atgaagcgaa taaagcaacc atcctcatgc gtgtcaagga aggggctgct
    53101 gactaccgct acttcccaga accagaccta cccctctttg aaatttctga cgagtggatt
    53161 gaggaaatgc ggactgagtt gccagagttt ccaaaagaac gtcgtgcgcg ttatgtatct
    53221 gaccttggtt tatcagacta cgatgctagt cagttgactg ctaataaagt cacttctgat
    53281 ttctttgaaa aagctgttgc cctaggtggt gatgccaaac aagtctctaa ctggctccaa
    53341 ggggaagtcg ctcagttctt gaatgctgaa ggtaaaacac tggaacaaat cgaattgaca
    53401 ccagaaaact tggttgaaat gattaccatc atcgaagacg gtactatttc atctaagatt
    53461 gccaagaaag tctttgtcca tctagctaaa aatggcggtg gcgcgcgtga atacgtggaa
    53521 aaagctggta tggttcaaat ttcagatcca gctatcttga tcccaatcat ccaccaagtc
    53581 tttgccgata acgaagctgc tgttgccgac ttcaagtcag gcaaacgtaa cgccgacaag
    53641 gcctttacag gattccttat gaaggcaacc aaaggccaag ccaacccaca agttgccctt
    53701 aaactacttg cacaggaatt ggcgaagttg aaagaaaact agacagaaca aaaccagccc
    53761 taaggttggt tttttcttct ctaccaactc ccaataacta ttttggcttt atttccagag
    53821 tattttatgg taaaatgaag agtaataata tttattaaag aggtaaaaac atgattgaag
    53881 caagtaaatt aaaagctggt atgacctttg aaacagctga cggcaaattg attcgcgttt
    53941 tggaagctag tcaccacaaa ccaggtaaag gaaacacgat catgcgtatg aaattgcgtg
    54001 atgtccgtac tggttctaca tttgacacaa gctaccgtcc agaggaaaaa tttgaacaag
    54061 ctattatcga gactgtccca gctcaatact tgtacaaaat ggatgacaca gcatacttca
    54121 tgaatacaga aacttacgac caatacgaaa tccctgtagt caatgttgaa aacgaattgc
    54181 tttacatcct tgaaaactct gatgtgaaaa tccaattcta cggaactgaa gtgatcggtg
    54241 tcaccgttcc tactactgtt gagttgacag ttgctgaaac tcaaccatct atcaaaggtg
    54301 ctactgttac aggttctggt aaaccagcaa cgatggaaac tggacttgtc gtaaacgttc
    54361 cagacttcat cgaagcagga caaaaactcg ttatcaacac tgcagaagga acttacgttt
    54421 ctcgtgccta atctctagaa agaggtcatt ctatgggaat tgaagaacaa cttggcgaaa
    54481 tcgttatcgc cccacgtgta cttgaaaaaa tcattgctat cgctactgca aaggtagagg
    54541 gggttcactc tttttcaaac agatcagtgt ctgataccct ttcaaaactt tcactcggcc
    54601 gtggcattta tcttaaaaac gtggacgaag aactcacagc agatatctat ctctaccttg
    54661 agtacggagt aaaagttcct aaggtagcgg ttgctatcca gaaagctgtc aaagatgccg
    54721 tccgtaatat ggctgatgta gaactcgctg ctatcaatat tcacgttgca ggtatcgtcc
    54781 cagataaaac accaaaacca gaattgaaag atctatttga cgaggacttc ctcaatgact
    54841 agtccactat tagaatctag acgccaactc cgtaaatgcg cttttcaagc tctcatgagc
    54901 cttgagttcg gtacggatgt cgaaactgct tgtcgtttcg cctatactca tgatcgtgaa
    54961 gatacggatg tacaacttcc agcctttttg atagacctcg tttctggtgt tcaagctaaa
    55021 aaggaagaac tagataagca aatcactcag catttaaaag caggttggac cattgaacgc
    55081 ttaacgctcg tggagagaaa cctccttcgc ttgggagtct ttgaaatcac ttcatttgac
    55141 actcctcagc tggttgctgt taatgaagct atcgagcttg caaaggactt ctccgatcaa
    55201 aaatctgccc gttttatcaa tggactgctc agccagtttg taacagaaga acaataaaaa
    55261 gaaaaagtgt ttgatatcta tcaaacactt tttctggctc ccactatcta aaaaaatgat
    55321 aatagatata attgtaaaca aaaatccaga taggttttgc atgattgaga aagttaaaaa
    55381 aactatggca gagaatcgtt aatctcagat tgtcggtaga acgataaaca agggcaaaaa
    55441 agaaaccaat cagactataa tataataaac taattggatc tctgtgagat agtatcaaat
    55501 ggctaatccc aaagatgata gcagatagga taacatccaa atagtacttg gactagggaa
    55561 agaaggtatt cataaaatac cctctatcaa gagtctcctc aaaaacagga ccgatgatta
    55621 caggcaggac aaaagataag atagtcgata aaaaggttgg ttgtccattt gaaaaaagca
    55681 cggtaaaata ctcatcatga atattcctat gattaatcaa atgagcatag cgtgcccaaa
    55741 aattaccgag aatctgataa accacataag ttgcaaataa gtagaagaca aatgaccagt
    55801 tccagctctt tttctcaaag ataaagagca tctttttctt ttttaacctc caaattaata
    55861 gaaggaaact tcccactaat cccattgtta aaataagaga atagacatca gctcctaacc
    55921 ctaaaatgat cgtcacatac aatccaattg tttgtggtaa ataggtagat agtaaaataa
    55981 taagcaaaaa tattccaaat tgtcttagtt tttttgtgtt tctcatcgta cttttttgaa
    56041 agattaccct gctcggaagc cgtacttcca agcatctata taagaattaa gtgccccttg
    56101 cctcatatag ggagcaaatt ctctataata taaccatcta ctatatccat cttcccaaac
    56161 agcaagacca cctgaagttt gctccaagtc ctcagttgaa agaactgtaa atgtatttgt
    56221 acctgtcatt gcaagtacct tcttaaaata gattgttgta ggctcacatt tatagtatat
    56281 ttcttttttt gtctatttta tagcccatct cctcaactgg caatttttcg acctgaatta
    56341 catttttcca taaaaaatga gacctttcta gtctcattta gtcattctta gtattttcta
    56401 aatcgttgat agcgttcttc cagcaactct tctagcggtt tttgtgaaag tctagccagc
    56461 tccgtttgga gttctttttt gacactctta atcagttctt tactagaaag tcctatttca
    56521 gaaatcacct tatccaccac gtccatttct aacagttcat gcgaagtgat tttcatcagt
    56581 tctgctgctt ccatagcgcg agtaccgtcc ttccataaaa tggaagcaaa gccttctgga
    56641 ctgagaatgg catagataga attttccagc atccagacac ggtccgcgac agctagagcc
    56701 agagccccgc ctgaaccacc ttcaccgata ataatggcga taataggaac tttcaggtca
    56761 ctcatttcca tgagattgcg agcgatagct tccccttgac cacgttcttc cgctccgaca
    56821 ccaggataag cacctgctgt attgataaag gtcacaactg gacggccaaa tttctcagcc
    56881 tgtttcatca accgcagtgc ctttcggtag ccttctggat gtggttggcc aaaattccgt
    56941 ttgaggttgt cttgcaaact cttgcctttt tggataccaa ccactgttac agcttgatct
    57001 ccaagccaac caataccacc aacaactgca ccatcatcac gaaaagaacg gtcaccatgt
    57061 aattggataa attcatcaaa aatgcctgtc gcaaaatcca aggttgtcaa gcgactctgc
    57121 tcacgcgctt ctctgactat ttttgcaata ttcatctagg actccctcca tgcaatctga
    57181 ctaggctagc aatcgtatct ggtaagtctc ttcttttgac aatagcatcc acaaagccat
    57241 gttctaatag gaattctgcc ttttggaaat cctcaggcaa gctttcacga accgtatttt
    57301 caatcacacg acgcccagca aaaccaacca agctctgtgg ttcagccaga atgatatcgc
    57361 cttccatagc gaaagaagct gtcacaccac cagtcgttgg atctgtcaaa atggtcaggt
    57421 aaaagagacc agcatttgaa tgacgtttaa ccgccgcaga gatcttagcc atctgcatga
    57481 gactcatgat tccttcctgc atacgggctc caccagaggc tgtgaatagg acaactggca
    57541 atttttcgac agtcgcatac tcaaacaaac gagtgatttt ttcacctaca accgtaccca
    57601 tagaagccat gataaagtta gaatccataa tcccaagagc cacagtctga cctttaataa
    57661 gagcagttcc tgtcacaacg gcttcatgca gacctgtttt ttcacgcata gatgccagtt
    57721 tcttttggta accagggaaa tgcaagggat ccttgctttc aatccctgta aacaattctt
    57781 tgaaggttcc catatcaatc gtcaaagcca agcgttcttg ggcagaaata cgaaaggtat
    57841 agctacagtg cggacagata cgttcacttc ccagatcctt ctgatagatg gtatgcttac
    57901 agcctggaca ctgggaaaat aattcatctg gaacctctgg cttagcttga ggtttttccc
    57961 taactgaacg attgggattg attcgaatat acttatcttt tttactaaat agagccattg
    58021 attccccttt tcggtttaaa ctcttaaagt cattttattc tttttcttga tatttaggta
    58081 agaaggtttc catcaagaag gaagtatcat aatccccagc aatgacattg cgatctgaaa
    58141 tgaggtcaag ctggaaatct gcattggtct gcactccttc aatctctaat tcatagaggg
    58201 cacgttgcat tttcatcaag gcgtcaaaac gattttcgcc gtgtactatg attttggcaa
    58261 tcatactatc ataataaggc ggaatggtat aacctggata aactgctgaa tccacgcgca
    58321 agccaactcc accacttggc agatagagat tagtaatctt acctggactt ggagcaaagt
    58381 taaaggctgg gttttctgca ttgatacgac actcgatggc atgaccgcgt aggacaatat
    58441 cttcttgctt aacagacaaa ggctgacctg ccgcaatgca aatctgttcc ttaacgatat
    58501 caacacctga aacaaactct gttactggat gttctacctg aacacgagta ttcatctcca
    58561 tgaaatagaa attgctactt gcttcatcaa gaagaaattc aatggttcct gcattctcat
    58621 agccaacaaa ctctgccgct cgaacagcag cagcacctat ttcatgacgc agcgtttttc
    58681 cgattgcaat cgagggactt tcttccaaaa ccttttggtt attcctttga agagaacaat
    58741 cccgttcacc caagtgaatc acatgtccat gctcatcacc taggatttga acctcaatgt
    58801 gccgagctgg atagataacc cgttctatgt acatggcacc attgccataa ttggccttgg
    58861 cctcactaga ggcagtttca aaggcagaaa cgaggtcatc tggtttttca accttacgaa
    58921 tccctttacc acctccacct gctgaagcct tgagcataac aggatagcca attttttcag
    58981 caacaatcaa agcttcttca gagttatgca cttctccatc tgaacctggt ataacaggca
    59041 cacctgcttt aatcatctga gcacgcgcat tgatcttatc ccccatcata tccataacat
    59101 aaccagatgg accgataaac ttgataccta cttcttcaca catggtcgca aatttggaat
    59161 tttcactgag aaatccaaaa ccagggtgaa tagcttctgc ctcagtcaag actgcagctg
    59221 atagaactgc attaatattg agataagact ctgttgcctt gccaggacca atacaaactg
    59281 cttcatctgc caaaagcgta tgaagagctt ccttatcagc agttgaataa accgctaccg
    59341 tcgcaatccc caattcacgt gccgcacgga taatacgaac cgcaatttca ccacgattgg
    59401 caattaaaat ttttcgaaac atggagaacc tccttagttc ccaattgcaa aagtaaggat
    59461 accactggct gcaagcttgc catccacttc agcctttgct tcaaccacag ctatggtgcc
    59521 acgacgtttt acaaaagtcg ctgtcataac caattggtcg cctggtacaa cttgcttctt
    59581 gaacttaacc ttgtccatac cagcgtaaaa gaccagtttt cctttatttt caggttttga
    59641 taactccaac acaccagcag tttgcgccaa ggcttccata atcagaacac ctggcataac
    59701 tgggtattga ggaaagtggc cgttaaagaa aggctcgttg atggtcacat ttttgatagc
    59761 aacaatggta ttctcgctca cttccaagac acggtccact agaagcatag gataacggtg
    59821 gggaagggct tctttgattc cttgaatatc gatcatttga tacgtaccaa tcctttgcca
    59881 aactcaacca tttcctcgtt agagacgaga atttccgtta ccacaccatc cttaggagct
    59941 gggatttcat tcatgacttt catggcttcg ataattacca atgtttgacc ttttttgaca
    60001 ctatcaccaa ctgtaacgaa ggcaggttta tctggtccag cagccaagta aaccactcca
    60061 acaagtggac tctctacaag atttccctca gtagccacac ttgcttctgc tggagctgga
    60121 acttcttctg ctacagtctc tgctggagca gatgtaggag ctactggact cggtgttgct
    60181 agaacgggtg ctggagcgac ttgagttgca acttcaggca caggtctcgc ttcattcttg
    60241 ctaaactgca actcatccgt cccattttta taagaaaatt ctctcaaact tgactggtca
    60301 aattgagtca tcaagtcttt aatatcgttt aaattcatac ttatctattc tcccaacgtt
    60361 tgaaagcaag aactgcattg tggcctccaa aaccaaaagt atttgaaata gcgtatggaa
    60421 tttctttctc caagccttgt ccataaacga cattaacttc gatataatct gatacttcac
    60481 ttgtcccagc tgtcattggt acaaagttat gacgcatagc ttcgatggtg acgatagctt
    60541 ctactgcacc cgcagccccc agcaaatgtc ctgtaaaaga cttggttgat gatacaggta
    60601 cttccttacc aagaacagct acgatagctc cactttctcc tttttcattg gcaggagttg
    60661 acgttccgtg agcattgaca taggctactt gctctggaga aatctcagct tcttccaagg
    60721 ctagtttgat ggccttgata gctccctgac cttctggatg tggagaagtc atgtggtagg
    60781 catcacaagt atttccgtaa ccaaccactt cagccaggat agtagctcca cgtttttcag
    60841 cgtgttcaag actttctaga accaacatcc ctgaaccttc acccataaca aacccattgc
    60901 gatccttatc aaatgggatc gaagcacgag ttggatcctc tgtagtagag agagctgtta
    60961 aggcttggaa accagcgatg gcaaaaggtg tgatagaagc ttctgttcct cccaccaaca
    61021 tcacatcttg gaaaccaaac ttaatggagc ggaaggcatc cccaatcgca tcatttgatg
    61081 aagagcaggc agtattgata gatttacaaa caccgtttgc accaaaacgc atggctacat
    61141 tcccagaagc catatttggt aaagcttttg gaagagtcat tggtttgaca cgtttgggtc
    61201 ctttttcatg aaggcgaagt acctgatctt caatttcctt gattccacca ataccagatg
    61261 caacgataac accaaaacga tccctattaa gagcctctac atcaagattg gcatgattta
    61321 cagcctcttg ggctgcatac aaggcatata aagaatagtt atcaaaacgg ttggtatctt
    61381 tttttacaaa gtatttatcg aacggaaaat cttggatttc tgccgcatta tgcacatcaa
    61441 agtcactatg atcaaatttt gtaatgccac caatgccgat tttcccagtt gctaaactat
    61501 tccaaaattc ttctggtgta tttccgattg gagatgttac tccataacct gttaccacta
    61561 ctcgatttag tttcattctt ttcacctcta gctttcgcta catacttaag ccaccatcaa
    61621 tggcaaccac ttgaccagtt agataatctt ggcctgctaa aaatactgtc aaatctgcaa
    61681 cctgctctgc ctgcccaaat tctttcatcg gaatctgagc tagtgtagct tccttaatct
    61741 tatctgataa gatagctgtc atatcagact caatcattcc tggagcaatc acattgactc
    61801 gtatattccg actagcgacc tcgcgtgcca cagacttggt aaagccaatc aagccagcct
    61861 tagaagcagc atagttagct tgaccaatat tccccatcaa accaacaaca ctagacatat
    61921 taatgatagc accttctctg gctttcatca tcggtttcaa gactgattgt gtcatattaa
    61981 aggcaccagt cagattgacc ttgagcactt tttcaaaatc tgcttctgtc atcttgagca
    62041 taagagtatc ttgggtaatc cctgcattgt tgaccaaaac atctactgaa cccagttctg
    62101 caatagcttg atcaatcata cgcttagcgt ctgcaaaatc tgatacatct cctgaaatgg
    62161 gaaccacctt gataccatag tttgaaaact cagcgagcaa ttcttctgag attgccccac
    62221 gactgtttaa gacaatgttg gctcctgctt gagcaaactt gtgggcgatg gcaagaccaa
    62281 ttccacgact cgaacctgta ataaagatat ttttatgttc tagtttcatt tttttccttt
    62341 caaaacttct acttatttta gtctattttt ctaaaagtgc tactaaactc gcttgatctt
    62401 ccacatgagc taagtgagca gtttgatcaa tttttttaac aaaacctgac aagactttcc
    62461 ccggtccaat ctcgataaag ttgcttatgc ctgcttcttg catgacccca atactttcat
    62521 agaaacgaac gggttccttg acctgacgcg tcaagagctg agcaatgtcc tctttttgca
    62581 tcacagcagc ttctgtattg ccgactaggg gacaagtaaa atttgaaaaa cttacctgag
    62641 ctagagtttc agctagtttc tggctagcag gctcaaggag agcggtgtga aagggacctg
    62701 acaccttaag aggaatcaag cgtttggcac ctgcttcttg caaaagttca accgctcgat
    62761 caactgcaac cacttctcca gcaatgacga tttgtgcagg tgtgttatag ttggctggag
    62821 taaccactcc aagttcagaa gctttttgac aggcttcttc aatgacctct actggcgtat
    62881 tgagaactgc taccatcttg ccagagtcag caggagccgc ttcttccata taggctccac
    62941 gcttagctac caaggcaacc gcatcttcaa aatccaaggc gccgcttgcc accaaggcag
    63001 agtattctcc aagagacaaa ccagcaacca tatcaggctg atagcccttt tcttgcaata
    63061 aacggtagat agcaaccgaa gtcgctagaa tggctggttg cgtatagcgg gtctgattga
    63121 gtttgtcttc ttccgtatcg atgagataac gtaaatcata accgagcacc tgactcgctc
    63181 gatcaatcgt ttctttgaca atcggatact gatcatagaa atcccgtccc atccctagat
    63241 actgggcacc ttgaccagca aataaaaagg ctgttttagt catttcttac aactcctgcc
    63301 cagcgagagg cttcttcttg aattttctta gcggctccgt aatacaaatc ttttaggatt
    63361 tcttcagctg tttcttcttt agaaacaagc cctgcgattt gacctgccat gacagagcca
    63421 ccatccacat caccgtgaac aactgctttg gctagggcac ctgctcccat ttgttcaaag
    63481 atttctaaat caggatcttc ctgcttaaag gcatcttttt cagccagttc aaaatctcta
    63541 gtcaactgat ttttaatagc acgaacagca tgaccaaagt gctgagctga aatcgtagta
    63601 tcaatatccc ttgcttttaa aattttctcc ttgtagtttg gatgggcatt cgactctttt
    63661 gcaactacaa accgtgtccc cacctgtaca gcctctgcac ctagcataaa gccagccgca
    63721 gcaccttcac catccgcaat tcctcctgca gcaataacag gaatagatat agctgtggct
    63781 acctgtcgca ccaaggtcat ggttgttaat ttaccgatat gccccccagc ttccattcct
    63841 tctgcaataa cagcgtctgc accgattttt tccatgcgtt tagctaaagc gacactagga
    63901 acaacaggaa taacgattat cccagcttca tggaaacgtt ccatatactt gcttggattt
    63961 cctgctcctg ttgtgacaac tttaacacct tcttcaataa cgagatccac gatatcttcc
    64021 acaaagggag ataagagcat gatgttgacc ccaaagggtt tatcagtcaa tgatttgatt
    64081 ttatcaatat tggccttgac aacttctttc ggggcatttc ccccaccgat aattcctaat
    64141 cctccagcct tggaaacagc ccctgccaaa tcaccatcag caacccaggc catccctcct
    64201 tggaaaatag gatagtcaat cttcaataat tctgtaatac gcgttttcat agtgcctcca
    64261 accttccttg cttacgtaat agttcgattt caccataatt tgacagtcaa actattacct
    64321 aaacaagagg gagtgggttt ctccctactc cttctactaa tattctgctt attttgcttg
    64381 ctcttcaacg taagcaacca agtcaccaac tgttttcaag tcattttctg cttcgatttg
    64441 gatatcaaaa gcatcttcga tttctgagat tacttggaac aagtccaatg aatctgcgtc
    64501 caaatcatca aaagttgatt caagtgttac ttctgatgcg tcttttccaa gttcttcaac
    64561 gataatttct tgtacttttt caaatactgc catgatagga ctcctttaaa ataaatagtt
    64621 tttttataac aatgtgttca ccacatgatt acctaaattg taagaatgag cgtgccccag
    64681 gtcaagcctc caccgaagcc tgatagaaga acagtctggc taccatctaa agggatgaga
    64741 ccttgttcta cacactctga aagtaaaatc gggatactgg ctgcactggt attgccatat
    64801 tccatcatat tggctggaag tttggctcgg tcaacaccaa tttttctagc catcttatcc
    64861 aaaatacggt cattggcttg atgaagtagc agataatcca agtctgtcac ctctatagga
    64921 gattcatcaa tagtctgctt gatagacttg gctacatctc gaatggcaaa atcaaagact
    64981 gtgcgtccat ccatcttcaa aaacgaatct gcactttctt gatctgaaaa tggagaatgc
    65041 aaacctgaat gcccataagt taaacactcg ctgcgacttc catcgctatt gagactctca
    65101 gctaagaaat gctcttgctc gctagcttct aacaagacac caccagcacc atctccaaac
    65161 aacacagctg ttgatcgatc cgaccaatcg actgccttag agagggtttc actaccaatc
    65221 accaagcctt tttgaaagcg accagaagcg ataaactttt cagcagttga aagagcaaat
    65281 acaaatccac tgcaagccgc ggttaagtca aaagcaaagg ctttattagc gccaatatta
    65341 gcttgaacac gagcagctgt agagggcatc atcgaatctg gagtaatggt agctaggatg
    65401 ataaaatcca gttcttttcc tgttattcca gcttttgcca tcagtttctt agcaacctct
    65461 gtagccaaat cactggtaga ttctgttctt gaaatatgcc tttgtcgtat tcccgttcga
    65521 cttgaaatcc actcatcatt ggtatccata atctgagcca agtcgtgatt tgtaaccact
    65581 tgctctggca cataatgagc aacctgactt atttttgcaa aagccattat ttcaaatcct
    65641 ccaaaaattg gtaaagatta gtcaagcctt tacccatgac agcaatttct tcctcgctca
    65701 tgccatcaat aattttttct accatggcct tgtggaagcg tttatgcagt ctatgaatca
    65761 agcgaccctt ctttgtcaaa tgcagatgca ccacacgacg atcctgttct gaccgaactc
    65821 gctcaatgta gcccttacgc tctaaattgt tcaaacttgt cgtaacagtt ccaagagtta
    65881 ccatcaactc ttttgacact tgacttggag tcacatctgg agccttaccg atgacatcaa
    65941 tcgtatgcat ttctttgatg gagatatcct taaaacgact acctctcaag ttcacttcct
    66001 caattacaag gacattgtta aatatagatg ttaaatattc attgattcgt tggtagtcca
    66061 tttttcatat ccctccttct tcaaaaaact tttacaatca aaacatttga cagaaagaat
    66121 tatatcaaaa ttcaaagaat gatgcaagta ttttttattt tcctgtaaat ttaggtcttc
    66181 ttctctccga atgagctcgc actccttctt tgaaatcctc tgtttgagct aaggatttct
    66241 gtaggttcag ttctaaagta gcgtaaccct gccagtcttt aaattggctc tcccaaacca
    66301 acttcttaat ggcagcatag gaattacttg aagcacgtct taatttttta agaagctgtt
    66361 ctctcgtctt ttcaagtttt tcagcttcag aaacgcggta aaccaacccc cattctaggg
    66421 ctttttctgc cgttaaagcc tctcctgtca tagctaattg agcagcacgc gtcacaccga
    66481 tactgcggct caagagatga attccccctg catctggagc caaaccaaca ccaacaaagg
    66541 cttggataaa cttagcctta tccgtcgcca aacagaaatc tgccgcaaca gccatattcg
    66601 ctgcggcacc tgcaacagca ccgtcaactt ccattaaaac aggtttggct atttgcttga
    66661 ttttataaga aatcgtattg accaactctg cgatttttgt caatgatgga atatcatcct
    66721 catccactgc ccgcttcatc tctaccaaat ctcccccaac tgagaagacc tttccattgg
    66781 cattgattaa gataaaatgc acagctggat tttcttctgc caaagtcaga gcttctaaaa
    66841 tctcctcaca catgggaata tgaaaaccat ttgcgacctc aggacggttc aaggtaagga
    66901 ttgccaagtc ctcttcaagc tgataaataa tgtgttccat cagggctcct ttttatttta
    66961 taagcagttt atactcttcg aaaatctctt caaaccgcgt cagcttccat ctgcaacctc
    67021 aaaacagtat tttgagctga cttcgtcagt cttatttaca acctcaaagc agtgctttga
    67081 gcagtctgcg gctagcttcc tagtttgctc tttgattttc attgagtgtt aaattatttc
    67141 actgtcaaag tatatctttt ttaggagcag aaagcaagaa aaaatcgact gaaagtgtct
    67201 cagccgataa gaaaggctcg ctttaggcta gaacgcatct tattttcttc attgaaaaaa
    67261 gcctttcttt ctgctataat cgtataaaat acttacttta ggagttctta tgaaagttgt
    67321 taaatttgga ggtagttctc ttgcctctgc tagtcaatta gaaaaagttt taaacatcgt
    67381 caaaagcgat tcagagcgtc gttttgtagt cgtttctgcg cctggtaaac gcaatgctga
    67441 agatactaag gttacggatg ccctgattaa atactaccgc gactatgttg cgggtaacga
    67501 tattagcaag agccaaagct ggattatcga ccgctatgct gctatggtta gtgaattggg
    67561 actaaaacca gctgtgctag aaaaaatttc taaaagcatt cacgccttgg ccactcttcc
    67621 tattgaagaa aatgaatttc tctacgatac tttcctagca gccggtgaaa ataacaatgc
    67681 caaattgatt gctgcctact ttaaccaaaa tggtatcgat gcacgctata tgcaccctag
    67741 agaagctggg attgtggtca caagtgaacc tggtcacgct cgcatcattc catcaagtta
    67801 tgacaagatt gaagaattga caaacaccaa tgaagtcctt gtcattcctg gtttctttgg
    67861 tgtcactaag gaaaatcaaa tctgtacttt ctcacgtgga ggttctgata ttacaggttc
    67921 tatcattgct gctggtgtca aagccgacct ctatgaaaac tttacggacg ttgatggtat
    67981 ctttgcagcc caccctggta ttatccacca accacactcg attcctgagt tgacctaccg
    68041 tgaaatgcgc gagttggcct atgcaggctt ctcagtcctt catgacgagg ctcttcttcc
    68101 tgcctaccgt ggaaaaattc ctctggttat caagaatacc aacaaccctg accatccagg
    68161 tactcgtatc gttctaaaac acagtaatga tgaatttcca gttgtgggaa ttgctggtga
    68221 ctcaggcttt gtcagtatta acatgtcgaa atacctcatg aaccgtgagg ttggatttgg
    68281 ccgcaaggtt ctgcaaatcc tggaagaact taacatcggt tgggaacata tgccaacagg
    68341 tatcgacgat ctttctatca ttctccgttc tcgccaacta actcccatca aggaagaaga
    68401 aatcctgcgt cagttggttc aaaaggctaa agtagatcat gcagaaatcg aacacgacct
    68461 ttctatcatt atgattgttg gtgaaaaaat gaagagccac atcggagtga ctgctactgc
    68521 gacacgcgct ctatctgaaa acaaaatcaa catccagatg atgtctcaag gttctagtga
    68581 agtttctatt atgtttgttg tcaataaaga ccaagagaaa gcagcaatta aagccctcta
    68641 caatgccttt tttggagaaa gtaaggaaga ctaagcatgg ctcaatcact taacaaaaca
    68701 gtactcctca gtacgacagg cacttcctac ctctctatcg ctgggaaagt tgggaaattc
    68761 cttgtcggag atcaggcttt ggaattttac ccagatgtca atgtcgaaca atttatccag
    68821 attccttgga gccatatcaa tcagattgga gccaatgtca ctggatgcaa aatcagccgc
    68881 cacttcgaag tctttacaga caaaggaaaa ttcctctttg cttcaaaaga ctcaggtgcc
    68941 attctcaaaa ttgcacgcga aaaactaggc aatgacaagg tcgtcaaact tccgaccctg
    69001 attcagacaa ttagccaaaa atttaaaaat ctatttgcaa aaaagtagaa actttagtat
    69061 aatcatagca acggataagt aggttatctt cttctttcag aaagtctgcg ggtactgcga
    69121 gcagatagga gggataggtg aaattctacc gttagtaaca attacataca caatcaagtg
    69181 cacacctgtg aagttggatg gaaccgtggc cctgccactc caacgttttg tcaggcgtgc
    69241 ttttttcata aaggagttct tatgttagat atcaaacgta ttcgtacaga ttttgaagct
    69301 gtcgcagaaa aattagctac acgtggtgta gatgctgctg tcttgaatga aatgaaagaa
    69361 atcgatgcta aacgtcgtaa catcttggtc aaggttgaaa ctctcaaagc agaacgtaac
    69421 acagtttctg ctgagattgc ccaagctaag cgcaacaagg aaaatacaga tgacaagatt
    69481 gctgccatgc aaaatctatc tgctgaggtt aaagccttgg atgctgaatt ggcagaaatc
    69541 gatgctaaat tgacagaatt tacaacgact cttccaaata tcccagctga cagcgttcct
    69601 gttggggctg acgaagacga caatgtggaa gttcgccgtt ggggtactcc acgcgagttt
    69661 gacttcgaac ctaaagctca ctgggatctc ggtgaagacc ttggtatcct tgactgggaa
    69721 cgcggtggta aggtaacagg cgctcgcttc ctcttttata aaggcctcgg tgctcgtttg
    69781 gaacgtgcta tctacaactt tatgttggat gaacatggaa aagaaggcta tactgaagtc
    69841 atcacacctt acatagtcaa ccatgattct atgtttggta ctggtcagta tccaaaattt
    69901 aaggaagata cttttgaact cagcgatacc aactttgtct tgattccaac tgctgaagtt
    69961 cctctgacaa actactaccg tgatgaaatc ttagacggca aagatcttcc aatctacttc
    70021 actgctatga gtccgtcatt ccgttctgag gctggttctg ccggtcgtga tacgcgtggc
    70081 ttgatccgtt tgcaccaatt ccacaaggtt gaaatggtca aatttgccaa accagaagaa
    70141 tcttacgaag aattggaaaa aatgacagcc aacgctgaaa acattcttca aaaactcaac
    70201 cttccatacc gtgtcgttgc tctctctact ggagatatgg gcttctcagc tacgaagact
    70261 tacgacttgg aagtgtggat tccagcacaa aacaattacc gtgaaatctc aagctgttca
    70321 aacacagaag atttccaagc ccgtcgtgcc caaatccgtt accgtgatga agcagatggc
    70381 aaggtgaaac tccttcatac cttgaacggt tctggacttg cagttggacg tacagtggct
    70441 gcaattcttg aaaattacca aaatgaagat ggttctgtga ccatcccaga agcacttcgt
    70501 ccatacatgg gtggagctga agtcatcaaa ccataaaaaa taaggtttag ctatttctag
    70561 ctagaccttt tttcgtaacc aaatcagata agcacctagt acaaagaata aaatagttag
    70621 gcatataatg gtttcagcca ataccaggta atccagaaat ggaagtttca aaattccctg
    70681 agccatcttg agcgaggtcg ctgtgataat ggttgggaag gtgagggctg agaaggctgg
    70741 ttgaaaacct tgttttaaaa tgttgggcag acgagttaaa acaaagaaaa agaaggattg
    70801 agaagccaaa atcatgacaa tcaagaccca agtcggcagg ctggttcctc ctactcgaac
    70861 tagagaagcc aagagtagag agaaaggagc acagtagatt ccttcttgtc caagcaaggc
    70921 tagtgggagt ggatgtttct ttaaatcgct ataaataagg ggatagagat agaaggtcaa
    70981 gagaaaacca aaactcaagg tcgcataggc aatttcgata atacctacca gaggataggt
    71041 caaggcagcc actgctatcc ccacatagag aaccgtccag cttggagtgg catgaaccct
    71101 ccgctctgga caagcaaact tgatggtaaa accagcaatc aaggtcaaat ccaagagaaa
    71161 tgaaaaccac caaatccctt gtgctaccaa aggaagataa gagaatacgc gaaagacata
    71221 ggtcgataaa atcatcccag ccataggaaa ggttgccatt cctgacaaaa gagggggctt
    71281 ggtcaattct tgcttggttt ctttccaatt aaagagatgc agaattagaa agtaaatcca
    71341 taaaaccaaa ccagtcagac taaaaagatg ggatagaact ggcaacatat ctaaaataag
    71401 atttccagct cctgccaaac ctagcaaaca acctgaaaat actaagggga gttttttcat
    71461 cctaacctcc aataatcatg ttagtttcag tataacataa aagcgcttaa atgaggattt
    71521 aaaaaaacga agtccgatta tttcagactt cattttactc agatatgaat taggcataag
    71581 gttgcaattc tggattaatt ggtgtattag ctaagttgtt ggcatagtta cagaggattg
    71641 ctaggctgac accgaaaacc acatccaagg cattttgttg agtgtagcca gcttctaaaa
    71701 actcagacaa ggcttcatct cctacacgac ccttggtatt gataactgcc aaggtaaact
    71761 tagctagggt atccaattta ggatctgttt caattggagt acgattgcga agagcttgaa
    71821 tcaagtcatc attcatctgg atttgtttga tggaaaaggc tgtgtgacct gcgacacaga
    71881 aggcacaacc attggtcacg gctgccgtga tttgcaccac ttcacgctca acgggtgtca
    71941 ggctgttgcg acggtggata gatgagacaa tttggtaggc ttctaaaaca gtcggggcat
    72001 tggccaagag accgattagg ttgggaatat agccattgtt gtctttttct actgtttcaa
    72061 gaatttcttt cacttctgct ggtgctgact ctactgtatg gatagtaaat gttgtcataa
    72121 gatacctctt ttcttattat tgacactaat attattggaa aatcttataa aatcctgatt
    72181 cctaagttta tctaagataa agctttattc tctcataaga ttttcgttgt tatattagtt
    72241 tatcacactt ccaatcactt gcataatata tattatatat caggctgata aaaattattt
    72301 ataggcaaaa aaatcacacg agctgtgtga ttccattatt tgtcaaaata ctttttagtt
    72361 tcagcaataa cgactggcga caagaccaag agggcaatca agtttggcag agccatcaag
    72421 gcgttaacga tatctgcgat aatccagacc atatccaact cgataaatcc tcctaacaag
    72481 accatgagca caaaaaccac acggtagagc cagataaagc gagccccaaa gaggaactca
    72541 aaacagcgtt ctccgtaata gttccaacct agaatcgttg taaaggcaaa aagtacaagg
    72601 aagatggtca agagggcagg cccaaagtat gaaaagactg ttgagaaagc tgactgagtc
    72661 aaggcaaccc cattcaagtc accactccaa actccagtta ccaagatggt caaaccagtt
    72721 agagtacaaa tgatgagggt atcaataaag gttcctgtca tggaaatcaa accttgctct
    72781 actggttcat ttgtcttggc agctgcagct gcaataggag cagaacccag accagattcg
    72841 tttgagaaca caccacgcgc cacaccattt tgaatagcca tccgaacgct agcaccagca
    72901 aatccaccta ccgcagcaag gggactaaaa gctgaggtaa agactaaagc gattgtgcca
    72961 gggatttttc cgatattaaa gaaaataact gtaagagttc ctaagatata aatgagggcc
    73021 ataaaaggaa caacagtagt tgaaacctta gaaatagact tgagtccacc aaagactgca
    73081 atcgctacaa agacagacaa gacgagagct gtgatggctg gcgaaatcgt cgttgtattt
    73141 tggatagatt ctgtaatcga gttgacttgg gtgaaggttc cgattcccaa gagagcaacc
    73201 aatactcctg ctactgcaaa caaaacagca agtggtcgcc acttttctcc catccctaga
    73261 aggatatagt gcatgggacc tcccgctact gcaccatggt cgtccttggt gcggtatttg
    73321 atggccaaga gtccttccgc atacttggta gccattccaa agaaagccgc catccacatc
    73381 caaaatagag ctcctggtcc accaaccttg atagccgtcg caactcctat gatatttcct
    73441 gttccaacag ttgatgccaa ggctgtacac agagctgcaa aactggatac atcaccatgt
    73501 cccttatcct ggataaaaat aagctgaaag gccttgggca gacgcaaaac ctgcaagagt
    73561 cctagccgta tggttaggta aatccctgtt ccgaccaata aaatcaagag gggcggtccc
    73621 caagcaaaag catcgattga tttaagcaat tctaacattt ccttctccta tcgtttcaac
    73681 cccaaaagaa agagcacatg caagatacat gtactctgga atgcttagat aaatgctaaa
    73741 aagcggtcta tcctagctct gtccttttac ctgagagttt gagcagttgc ctgccttgcc
    73801 ccttcggtgc ctttacggtc tctccagagt tccgtccatt tacagtcatg gaaaatcaaa
    73861 cgattcccca cttctattaa acttcattcg gtgttggtat ttaattgatt ctaattttac
    73921 aaaaaatgtt ggcttttgtc aatgtgttta ttagtaaaaa ttagttcaac agtttttact
    73981 ttataaagtc cagaatactg ctatccttta aaagtgacaa tagtcgcacc actgcctcca
    74041 gcattttgtg gggcatagcc gaaactcttg acatgtttgt ttctttgcaa gtatttggta
    74101 actccttcac ggatgactcc tgttccgata ccatggatga tatcaacttg agccatattg
    74161 ttaagcaagg cttggtcgat gaaggtatct agctcattca tggcttcttc atagcgcttg
    74221 cctcgaagat ccagtctagc ttgaggtcct cgcccagaag ttcgtttcac aacattgacc
    74281 tgtttcttct tgactggttt ttcttgctgg gcttgaacaa gatcaaactc tttctcttcc
    74341 aaggtcatct taatcaagcc aacttgggct tcccagcggc cgtccttgag ttgactggtc
    74401 aaggtaccac gctgaccata actgagaacc acgatatcat ctcccacctt tggagctcgt
    74461 tttttcttgg ccttttgaag gaccttgttt ttagacaagt ccactttttc aggagccaat
    74521 tttttcaact tggccttggc ttcaatgatt tcgtggggct tgagttggga tttactgtgg
    74581 agatttttga gaatctggtc actttcactt agggccatat ccacaatctc agcagcctgt
    74641 tcacgcgcct tgttaagctc ggtttccttt tcacgattaa gctcgttgta gagttttttt
    74701 agcgcacggt tcatcttgag attttcttgc tccacctcac ggatattgtc caagcgtttg
    74761 cggctttcca gcgtctgctc ttctaattgc tcaatgatac gattgacgtc attgtcctga
    74821 tcgatctgct gactggcatc tcctacgata acttcagata ggcctagacg tttggcaatt
    74881 tcaaaggcat tacttcggcc aggaacaccc tgcataaagc gataggtcgg gcgaagagtt
    74941 gcagtatcaa actccatact ggcattttgc acaaaggctg tctcaatacc gtaggccttg
    75001 agttctggat agtgggtcgt cgccatggtc ttgatttgac gcaggcgaag gtcctccaga
    75061 atagccatgg caagggctgc tccctcttgg ggatcagtac cagcccccaa ttcatccaaa
    75121 agtaagagtg aatgttggtt gaccttgcca agaatatcca cgatattggt catatggcta
    75181 gagaaggtag acaagctctg ctcaatagac tgctcatctc caatatcaga aaaaatttct
    75241 tcaaaaatac caacacgact tcccttgtct gctaaaatcg gcaatcctga ctgggccatg
    75301 acctgtgtca agcccagagt tttgagcatg atggtcttcc cacctgtatt gggacctgta
    75361 atgacaatag ctgttaaatc ttgaccaaaa tagacatcat ttgcgacggc atttttgacc
    75421 aaaggatggc agacatggag cagttgaatc tcttgatttt ctgacagctg aggcacgact
    75481 gcttgtcttt cttggataaa tcgaaccttg gcacgaatca agtccagatg accgataatc
    75541 caagcatcat tagcaatctc agccgcatga gggcggacac gctcagaaat ttcttggaga
    75601 atgcgaagca tttcatagcg ttcatctgct cgcagactag caatttcttc gctcagtttg
    75661 actacctcac gtggttcgat atagacggtg tttccactag cagaaatatc atgaacgaca
    75721 cctgcaatct tattgcggta ggtgtttttg actggtaaaa cctgacggcc atttctgcta
    75781 gcaacaattc cttccgtcaa catctgcgct ttttgcttga gcaagtcttg taaaacatcg
    75841 cgtacctgac tctcgctatc atgtattttt cgacggattc gcgccaattc ttcactggca
    75901 aaattttcaa tgaaacccgc atcattaaag gcctgaagat ttccttgtaa ttgcggaaaa
    75961 tcatgtaatt tctcaaacca aagggctaat tcttccaagc tgacattttc cagattggcg
    76021 taaaaacttt gaagttctcg gctggcaaga agcacgcgtt tcaagagtag gaactcctcg
    76081 atattgagat ccgctcccat ctccaacctc ttgcagactc ctgcaatttc cttagttgag
    76141 agaatagtaa aatgcggttg ctcgacgaaa agagcctgca tttccttcat ctcagcaaaa
    76201 gcctgtttga ttttatctgc tttggcagtc ggagccagtt gtctcaattg ctccaagccc
    76261 tgctcggtca acaaatgagg ctcaaacaag gccttgacct tatcgaactc taatgtttct
    76321 aatattttct tattcatctt tatttccttg tctttgaatg tctaggtgtg gtagcttttt
    76381 acattctgat agattcgagt caaatctgta aacaaagggc taggaaaact cctgcccttt
    76441 ttatccgatt aaatttgtca cccagatttg tttgagccaa ctggttgtta tcggtatgct
    76501 ctggatgatg tgttttgcga cgatactctt ttcaagagga ttttgtataa ctgccatggg
    76561 gatggtcgcc aagattgtca aggccatttg caagacaaat aaggtcacca acatggacaa
    76621 gatacctgct gaaacttgga acaacttacc acccagtttt ttgctaggaa tcaagtgtaa
    76681 gagaagacca agcaaacgac caatgctata gacaatccca aatacaagca agtagccgat
    76741 gcctgcataa aagaccttat ccagctgaaa gagttgatcc gatgggaaaa agaaagtccc
    76801 ctgaccttcc tgcgaatttg cataagggag caataaatgg aattgctctc caagcccctt
    76861 ataaaactgg ccagccataa aagccgatgc catggctgaa atcaggtaat aaacctgtaa
    76921 gagcaggcct ctccgatagc cgatataaaa tccccaaacc aagaccaata gaagaaggaa
    76981 tgaaatcata aggaatcctc aatcttgctc tgttcttgct tacaagtcac aagcttgtga
    77041 cggagttctt ctagctcttg ctccttatcg tcaaattcaa tctcacggct gagctgagtt
    77101 gataaacagt tgactgccaa caaaagagcg attgtttcat catctgcgct aggcatttgt
    77161 tctttaattg cttggtattt ttctgtcgca accttagcga tttcctccat aaaaaggttg
    77221 tcatgttcgc ttgtcaaggt taacgatttt ttcccgaatg taaatttgaa tcgatttaga
    77281 tttgccataa aattcacctc acgatattat accaaaattc gctaattttg tcagttttta
    77341 caaattttac tgcttttgtg gtacaataga aactatggca agtatcacac tcacaccaag
    77401 cgaaaaggat attcaggctt ttcttgaaca ctatcaaacc agtctggctc ctagcaagaa
    77461 tccctatatc cgctactttt tgaaactacc tcaagcaacg gtttctatct atacttctgg
    77521 aaaaatcttg cttcagggtg aaggggctga aaaatacgcc agtttctttg gctatcaagc
    77581 tgtagagcaa accagcggac aaaatcttcc tttgattggg acagatgagg tagggaatgg
    77641 ttcctacttt ggtgggcttg cagttgtggc ttcctttgtc acacctgacc agcatgcctt
    77701 cttacgaaaa ctcggtgtgg gagattctaa gactctgacc gaccaaaaga ttcgtcagat
    77761 tgctcctatt ctcaaggaaa aaattcagca ccaggcactc cttctctcac ccagcaagta
    77821 caacgaggtc atcggagacc gctacaatgc tgtttcggtt aaggttgccc tccataatca
    77881 ggctatctat ctcctccttc aaaaaggtgt tcagcctgag aaaattgtga ttgatgcctt
    77941 taccagtgct aaaaattatg acaagtactt ggcacaagag accaatcgtt tcagcaatcc
    78001 tatcagctta gaagaaaagg ctgagggcaa atacttggct gtcgcagttt cttctgtcat
    78061 tgcgcgtgat ctctttctgg aaaatcttga aaatttggga cgagaactgg gttatcagct
    78121 cccaagtgga gctggaacgg cttctgacaa ggtggctagc cagattttgc aagcctatgg
    78181 tatgcaggga ctcagcttct gcgccaaatt gcactttaaa aacactgaaa aagcgaaaaa
    78241 acgcttagaa aggtaagtta tgaattcatt taaaaatttc ttaaaagagt ggggattgtt
    78301 cctcctaatt ctgtcattac tagctttaag tcgtatcttt ttttggagca atgttcgcgt
    78361 agaaggacat tccatggatc cgaccctagc ggatggcgaa attctcttcg ttgtaaaaca
    78421 ccttcctatt gaccgttttg atatcgtggt ggcccatgag gaagatggca ataaggacat
    78481 cgtcaagcgc gtgattggaa tgcctggcga caccattcgt tacgaaaatg ataaactcta
    78541 catcaatgac aaagaaacgg acgagcctta tctagcagac tatatcaaac gcttcaagga
    78601 tgacaaactc caaagcactt actcaggcaa gggctttgaa ggaaataaag gaactttctt
    78661 tagaagtatc gctcaaaaag cccaagcctt cacagttgat gtcaactaca acaccaactt
    78721 tagctttact gttccagaag gagaatacct tctcctcgga gatgaccgct tggtttcgag
    78781 cgacagccgc cacgtaggta ccttcaaagc aaaagatatc acaggggaag ctaaattccg
    78841 cttctggcca atcacccgta tcggaacatt ttaagaaacc taagaggccg agaatcacca
    78901 atctcagcct cttcttctat cgtgagaaaa tgattggtaa ctatctaaac ttaccagaac
    78961 agaaacacct caactctcac ctattcatgc aaaggaattt tatggaagtt tatttttcag
    79021 gaaccattga acggattatt tttgaaaatc ccagcaattt ttatcgcatc ctcctcctag
    79081 aaatcgacga tacggacgca gaggattttg atgattttga aatcattgtc acaggaacca
    79141 tggctgatgt aattgagggc gaagactata ctttttgggg gcaaattgtc cagcactcca
    79201 agtatggaga acaactgcaa atcagtcgtt atgatcgcgc aaaaccaact agtaagggct
    79261 tggtcaagta cttttcaagt agccatttca aggggattgg tctcaagaca gctcagaaaa
    79321 tcgtggatac ctatggcgaa aataccattg acgaaatttt gcaacaccca gaaaagttag
    79381 aaggcatcac aggactctct gccaaaaatc gcgaggcttt cgtctccact ctccgtctca
    79441 actacggaac ggagatggtt ttgtccaaac tagccaacta cggcattccc aacaaactag
    79501 cctttcagat tcaagacttt tacaaggaag aaacccttga tgtggttgaa aattatccct
    79561 accagctggt tgaggatatc aagggtttgg gctttaccat tgctgaccaa ctagctgagg
    79621 aactaggcat cgaaagtcag gctcctgaac gcttccgcgc cggtctagtt cacagtcttt
    79681 ttcaggcctg tatggaaaca ggggacacct atgttgaagc acgggatttg ctggaacaaa
    79741 cccttactct ccttgagtct tcccgtcccg tggaactaga ccccagccaa gttgcccaag
    79801 agctctccta cctgatcgaa gaagacaagg ttcagcagat tgataccaag atctttgaca
    79861 acagcctctt tttcgctgag gaaggcatcc gcagtcactt ggttcgtatc cttgaaaaag
    79921 gaaaacagaa gagtcatgat ttagaaacca ttcaaaaaca tatcactact atcgaggaag
    79981 agctgggaat tgagtatgat aacattcaaa aacaggctat ctgtgatgct atccagaata
    80041 aggtctttat cctgacaggt gggcctggta ctggtaagac aactgttatc aatggaatca
    80101 ttgctgttta tgccctttta gaaggacttg acttcaggaa gaaaagcaat ctgcccattc
    80161 ttcttgctgc tccaactggt cgagctgctc gtcgcatgaa tgaattgaca ggtttgccta
    80221 gcgcgaccat acatcgccac ttgggaatga caggtgacga tgataccagt catctggaag
    80281 attacctaga tgctgagttt atcatcgtgg atgaattctc tatggtagat acttggctgg
    80341 ccaatcaact cttctccaat atctcttcta acagtaagat cctcatcgta ggtgacagtg
    80401 atcagctacc ttctgtcagt cctggacagg ttctagcgga tctgcttcat attcctttga
    80461 ttcctcagac tcgcttggaa aaaatttatc gacaaagcaa agaatcaacc atcgtcaccc
    80521 tagctagtca gattcgacag ggcatcttgc cagctgattt cacccaaaaa aaagctgacc
    80581 gttcctactt tgaaattgct agtggccata ttcctgccac cattgaaaaa atcttaggtg
    80641 ccgccctcag aaatggtatt cccgcccgtg atatccaagt tctggctcct atgtaccgag
    80701 ggacggcagg gattgatgct atcaatcagc tcatgcaaga cctgctcaat cccccacaaa
    80761 aagatcaact cagttttgaa gctcctcagt gtcactatcg taagagagac aaggtcattc
    80821 atttggttaa cgatgctgaa atcaatgtct ttaatgggga tttaggagct atcacagacc
    80881 tgattcctgg taaatacacc gaatcgaaac aagacgagat tgtcattgat tttgatggta
    80941 atgaagtctc ttacccccgt aacgaatggt acaagattcg cttggcctat gccatgagta
    81001 ttcataagtc tcagggaagt gagttcccag ttgtcatcct accgattact agtgctagcc
    81061 gacgtatgct ggagcgaaat ctcatctaca cagccattac acgtgccaaa agcaaactca
    81121 tcttactagg cgaattacaa gccttcgact atgctaccca acacatcgga actgcccgaa
    81181 aaacctatct gattgaacgc ttcagtgatc tactggagaa tgttgaagaa aagcaacaag
    81241 ctgtctctga aacagtcaca tcaagtgcct ctgaacaatc ctacatccta accgaagaaa
    81301 actgggaccg catcccagcc atgattggga ttacagacac agacctcaaa gagatttttg
    81361 gaaaatagtg catcagaaaa cccaccaatt cagatgggtt ttctgtttat taagattatt
    81421 ttactgttgc tgtgcttgta atcaattcaa cagctttttt gattgtgata tcatgtttca
    81481 acatgtcagc tgaaagcaag ctttgtactt gagcaacttc catgttgtag tctgctgcca
    81541 attgctcaac ttctttttgg atttcttctt ctgaagcatc aaatccttca gctttggcaa
    81601 ctgcttcgat aacaaggtta gtcttagtac gtgactcagc ttctgcttgg tattggttgt
    81661 gaaggtcttc ttgagtagtt ccagtgattt ggaagtacat gtcagggttg atcccttgac
    81721 gttgcaagtt cccaaggaat tcatttactg aacggtgaac ttcttcgtgg atcatttctt
    81781 ctggaagttc tacgatttca gcattttcta cagctgtatc aattgctgca ccttcaactg
    81841 catctttgta agcttcttct ttagcagcag ccaattcttt gcggtatttt tctttcaagt
    81901 cagcaagtgt ttcaacttct tcatcaatgt cttttgcaag ttcatcgtca agagctggaa
    81961 cttctttagc ttttacttca tggatagttg tcacgaattt agcttcttta cctgcaaggt
    82021 cttctgcttg gtagtcttct gggaatgtta cgataacatc aacggtttcg ccagctgagt
    82081 gacctaccaa ttggtcttcg aaaccaggga tgaattgacc tgaaccaagt ccaagtgaga
    82141 agttttcacc ttttccgccg tcaaattcaa caccgtcgat agaaccaacg aagtcgatca
    82201 caacagtgtc gccgttttca gcagcagctt ccttgataac caattcagtc aggttgttgc
    82261 gttcgcgttc gatacgctct tcaacatcag cgtcagttac ttctttttct acatcaactg
    82321 atacttcaag gtttttgtag tcacccaatt ttacttcagg ttttgtaacg acttcagcag
    82381 cgataaccca atcttgacct ttttccattg aagttacgtc aatttttggt tgggcaacca
    82441 cttcaagacc agcttctttt acagctgctt cataagcgtt tggcaaaaga gcgttcataa
    82501 cgtcttggta aagtgattct tcaccaaatt ttttatcgaa gataggacgt ggaaggtgac
    82561 ctttacggaa acctggaaca ttaagagatt tcttcactga cttgaagaca cggtccaatt
    82621 ctggtttgat ttggtcttga gagatagtga aagtcaagac accacggttt gtttctttgt
    82681 tttcaaatga tacagacatt ctgtcatttc tccttaaaat tttttaaata cagtctatta
    82741 taacattttc tataaataaa atctagacta atgcagccaa ttatagacaa caagcctttt
    82801 tcctaactaa aacactcata aagtatagac aattttagac tactttggat atcttttggt
    82861 tagtcatttt ccaaaactaa tttatctaat ttttcagtta tatagtagat tgaaactaga
    82921 atagtacacc tctacttcta aaacattttt agaaatcgat ttgactgtcc tgatcgattt
    82981 gtcctgttct tgtttcattt tactatatag atcgcattcg aaagaattcg ttccaaaatt
    83041 gcttggttcg ttcttctctt ggacgactaa agaattgatg ggcattattt ttttcaacaa
    83101 ttttcccacc gtccataaaa ataacatgat gggctacatc tctagcaaaa cctatctcat
    83161 aaagctgatc aaaaactcaa tctgaggaga aaatccaata aggctttcca taataaagga
    83221 catcctatca agatttttga acacccgata ggctgccttt ttccgatttt gaagactttt
    83281 tgtccagctt cttttacctt ataaataaca acaaaaatca aagacaggct agaaagatta
    83341 ccgcagataa ctcaaacagt gttttgaggt tgcagataag actgacgaag tcagctcaaa
    83401 gcactgcttt gaggttgtag atagaactga cgaagtcagc tcaaaatact gttttgaggt
    83461 tgcagatgga tgctaacctg atttgaagag attttcgaaa aagattaaat atactctaca
    83521 atttgctcaa tcaattcttg gtcgtctaaa cctgtaactt gtataacaac atctttgact
    83581 gattgtttag ccaacaattc acctaatcga atactttctt catcatttac atcgcgatag
    83641 tcaaaggcat agccaactgt tttaagtagg tttttatatg acaaactgag ttctttcaat
    83701 tcacgtatcg gccggatgaa tcgttcatta tagcctaatt ttcggattgg agtacgagct
    83761 acgcgactaa cctcgtccac tatgaaagga ttttcaaacc gttctataat gactttgtga
    83821 taattctcca attctttttt atcaaagttc catttggcaa tcaagagact ccgaatttca
    83881 gctaatacag attcaatccg agatttgata ttaggatttt gaagagcttc caaaattgtc
    83941 ttggcaccat aatgcgcacc aatgtaagct gaagttgcat gtccagaatt gactgaaaaa
    84001 agttttcgct caataaaggg ttctaaatct tcttcataat gcacatcttt tagacgtaaa
    84061 tctggatttt taagacgctt ggtttccacg acccattcat taaagggctc gaccacaaca
    84121 aaaagggaat cttcgtgact ttgtgctgga acaatcctgt ctactgcagc atttggaaaa
    84181 cctatgtagt tatcagcaaa tgtcaaacct tccggactta aatatttctt gacttcttga
    84241 taaagaaatt gagacccgcc aatcatattt tcacaggcca taacatccaa tgcctgtgta
    84301 tttcctgcaa ctcggcgagc ttcgattcct ttggctagaa gttcggcgat aaaagggagt
    84361 atattaggtc cgattgcagt agtaataata tccgtctttt gaatcgcttc aatgacttgc
    84421 tcaggatgtt ctttgctatt aatgccagcc acattagtta cttctatacg agactgtcct
    84481 ttctgtgcaa tttcaatttc atacttgccc ttttcattta gagcatgaat tatctgatta
    84541 ttgacatcca caaaatcaat atggaaacca tttttaaata gaatttcacc tataaaacca
    84601 cgaccgatat taccggcacc aaaatgaaca gaatgtttca ttcaatttct ccttttccta
    84661 tttgagggac atatatacta gatgacaaat gacgaaattc aattattcaa cagcatcaaa
    84721 taagcgcaat acttcctctt ttgactgagc atctgctagt ttaagaacat tatctacatc
    84781 tgcacagaag atagaaattt tctgaataat ttctaagtgt tcattaccaa taccagcaat
    84841 accaaaaaga accgttgcca cttgagggtt agatacattc ccaaaatcaa cccctctagg
    84901 gacttgaacg actgtaatac cagacttgag gacatcattt tttgctgcat ctgtcccatg
    84961 cggtatggcg ataaagttac ccatgtaaac agatagctct ttatctcgct caatcatggc
    85021 ttcaatatag tcttcattaa catatccacc ctcataaaga acttgcccac aataacaaat
    85081 agcttcctcc ttgttagaaa attgtttatt aagcttaatc aaatgttttt caagtttcat
    85141 attagttctc caatttctta attttttcgt taaaaatagt atttagcatc tgataaataa
    85201 tggattgatt tcccgtcttg taaatctctg tataaagatg attttcaata atcgactgac
    85261 taatagctgt cattaaatct ctcgcttcct cgctagcttc tttagacatt agcattagca
    85321 gacacctttt gacctcttct tcctctagtt tcattgacaa tgcggagata ggtagtttga
    85381 gttcaaacat agtaaaacta tttgttgtta ctttgctaga ctgactatgt aaaagcacca
    85441 gaccagtatt aggaatagcc ataggactat tctggaagtg agataacaat tttcttgtta
    85501 ggtaatctct gtcactcaca ttcttctgat attggatgat ttgttctacc gtgtgctcaa
    85561 atgattgatt attctccaat tgaaccaact cgaattgact caaaagctga ctactagata
    85621 ttaaataatc ttgcaagtca taacttttct ctggagcgat agcatcacgc gcgacaattg
    85681 tacgatgtgc ctgtacatac tgaagtcgtt cctgtaattc aagcaattct ttgacggttg
    85741 gaaaactaga aattacatcg atttcctgat tagtcagcgg cttggtagat aaaatataat
    85801 catactgact gagatcaata ctgtggtaat ctactagaga ctgaatatct atcaactcta
    85861 caaaaggagc aacactctta attttactga ctaataaatc tctagtgacc cgacgttcat
    85921 ccgttaaaag caaaacacgg actggataaa tctctggact acggcctaag ctagagataa
    85981 aatgtagggc aatcatgcca tactcatact ctgtatgaag atatttcgga aaaatatcat
    86041 tcactaaaag actgatgact gtataaagaa atttattcct ttcaactaaa atctggacag
    86101 attctggcaa attttcaccc tgaaaaagga tagggacgcc taaactgagc cgaatatgat
    86161 ggaaaagaaa attgaataaa accttgtcct taaaaaagtc aatcttggta tacatggaaa
    86221 ccgtatcaat cagatttgaa atattgtaga aaaattcacc atcaaatttc tccgtaaaga
    86281 gcggattgtc ctgacgttta atgattaatt catccaagat gctcgcaaaa tagataattt
    86341 cctgaatact ataaaattgt gcagtctgct tagagtaagt ttgaaaaatt ttttgagaaa
    86401 tttccaaagc ctgcttacta gtattaggtg aattttcaat gttttgctcc tgacctataa
    86461 gagataacaa gatcgcaaaa aacatcttca tcctagcatc catatctgga aaacctgaca
    86521 gttgcttatt aacaatctga ctggccagcc tagttctatc tgcttctaaa atatcaaagc
    86581 tcccaaaatt accggttgaa aaatctgcta ctgagataca gtttgtcagt aaaatagcca
    86641 aaaatcttct cttaccaact gaatcaccag aaatccgata acctttttgt cgttcaattt
    86701 tcagatcaaa gtctaaaaga cgcttatcaa tatctgaaat atcctgaata atagttacat
    86761 tactgacttt cgtgcactct tgcaatgctt cattggtgac aaaaccactc tcagtcagaa
    86821 ggcgataggt aatcaactct tgtctttctt ggggactata ctcaactaac acttcaagtt
    86881 ctgtcggcaa atcatccaac tctccagtca aaatatagta tttcccatgc ttcgttattt
    86941 cgattccata ttgctccatg ctatctgtca aatctgataa agttcgataa attgttctag
    87001 atgaaacctg taagatttca gtcatatctt gcattgaaag cttccctaca tgtaggaaag
    87061 ccttcaataa ttgttcttct cgtttggtta atagcattcg taatttagaa acctctagtt
    87121 ctatttgtac attctagcag ccattttgtc atattctggt gttgttacta aactatccac
    87181 aataagaaat tgagaattcg gtgctgcttg ctgcacttct gcctgtaaag aaatagttgt
    87241 tacaatcatt atgtttttag aattaaattc acctaattct gaaattttgg cagtagaaac
    87301 tggaatacga atattcttgt ttctaaagat agcccgaatc gtttcacagc ccatagttgc
    87361 agttccctgt gctttaccat aagcaactac tacagcatca atatggttaa ggtcaatttc
    87421 ctgactatct actggtgctg aagttggtat atctccttca atttctgcta ttggagaagc
    87481 tcctgttaat gaagctacaa tttcatcata acgaggggac gctaagaaat tatcaacaga
    87541 aacatgaata gcacttggac tcttgtcttt agctcttggt gtcagttctt cctgagtaac
    87601 aattaatgtt tttggtgtat caagcaaatt tgagattgcc tgattagata ctggaatctc
    87661 tagacctgct tttttaacct tatctcgaag aatactagct cccatagcag agcttcccat
    87721 accagcatcg caggcgaaaa tgattttttc cactgagtct gtcgaaacaa ctgcatcaac
    87781 agaagttgat actaactgac ctttagactg agccttagct gctttggtag ccgcctgagc
    87841 agcttcgagc gaatcctcag ttgacttgtc tgcatgaaga ataagggctg ctacaaggaa
    87901 agaaacaact gctgctacta aaacacctag aagaacattt atatggggcc aaacaccttt
    87961 tggcgccgta gccataatcg caataataga acctggtgaa gctggagatt taagaccagc
    88021 gtctaagagt tgaaaagtaa aagttccaga gatacctccc gccatagcag ctaaaaatag
    88081 agtaggcttc atcataacat aaggaaagta aatttcatga atccctccga agaaatgaat
    88141 aaccattgcc ccccaagaag aagatttagc agaaccttta ccgaatacag cataagctaa
    88201 tagaattccc aggcctggtc caggattagc ttccaatagg aagagaattg acttaccagc
    88261 ttgagctacc tgttctactc ccagaggagt aaaaatgcca tgattgaggg cattattgag
    88321 gaaaaggact ttagccggtt cgatgataat attagccata ggaaggaggc gagcattgac
    88381 aatagcctca acaccattcc caacagctcc agtaagagtc gatacgactg gaccgattgc
    88441 gtagaaagcc aaaagcaata atgcaaaacc aacgagacca gctgagaagt tattaactaa
    88501 catttcaaat ccgggacgaa ttttttcttg gaacttctca tcaaatttct tgatagtcca
    88561 tcctcccagt gggcccatta ccatagctcc gataaacata ggaacactag aacctgtaat
    88621 tgcaccaaca gtagcaatag ctcctacaac ggcaccacgt tggccatgga tcatatatcc
    88681 acctgtgtaa ccaatcagga ttggcaataa atacgttaac ataggaccaa caacagtagc
    88741 taactgttca tttggcagat agccatcagc gataaagagg gcagtcaata ctccccaagc
    88801 aataaatgct ccaatattgg gcataaccat atttgaaagc gatgtcccta gtttttgaac
    88861 cctgactttc aatgatactt tttcttccat tagatcatcc tccttttctt aaaactagta
    88921 tatacaaagt taaaaacctt taaaactaaa gttttgtcac agattttgtg tcaaaacatt
    88981 acttttgacg aggctgggca aaaaggctta aaaattataa aacgcatcat atcaggtgta
    89041 catgaactac accccaaaag ttagacagaa aaaatctaac ttttggggtg tttttattat
    89101 gaaattaact tatgatgata aagttcagat ctatgaactt agaaaacaag gatatatctt
    89161 agagaagctt tcaaataaat ttgggataaa taattctaat cttaggtaca tgattaaatt
    89221 gattgatcgt tacggaatag agttcgtcaa aaaagg
//
LOCUS       DAVMJI010000003        86086 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.003, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000003 DAVMJI010000000
VERSION     DAVMJI010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 86086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.003"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(723..815)
                     /locus_tag="VYR58_000196"
     CDS             complement(723..815)
                     /locus_tag="VYR58_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV3621430.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            976..1947
                     /gene="ruvB"
                     /locus_tag="VYR58_000197"
     CDS             976..1947
                     /gene="ruvB"
                     /locus_tag="VYR58_000197"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV3621431.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHAGLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            1928..2500
                     /locus_tag="VYR58_000198"
     CDS             1928..2500
                     /locus_tag="VYR58_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV3621432.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            2731..3489
                     /locus_tag="VYR58_000199"
     CDS             2731..3489
                     /locus_tag="VYR58_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV3621433.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALIKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            3498..4301
                     /locus_tag="VYR58_000200"
     CDS             3498..4301
                     /locus_tag="VYR58_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV3621434.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKIRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            4323..5582
                     /gene="rseP"
                     /locus_tag="VYR58_000201"
     CDS             4323..5582
                     /gene="rseP"
                     /locus_tag="VYR58_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV3621435.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRHKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            5595..7448
                     /locus_tag="VYR58_000202"
     CDS             5595..7448
                     /locus_tag="VYR58_000202"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV3621436.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPTLLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            7548..8927
                     /gene="bglA"
                     /locus_tag="VYR58_000203"
     CDS             7548..8927
                     /gene="bglA"
                     /locus_tag="VYR58_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV3621437.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            9119..10927
                     /gene="glmS"
                     /locus_tag="VYR58_000204"
     CDS             9119..10927
                     /gene="glmS"
                     /locus_tag="VYR58_000204"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV3621438.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            11046..12095
                     /locus_tag="VYR58_000205"
     CDS             11046..12095
                     /locus_tag="VYR58_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV3621439.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(12195..15992)
                     /gene="spuA"
                     /locus_tag="VYR58_000206"
     CDS             complement(12195..15992)
                     /gene="spuA"
                     /locus_tag="VYR58_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV3621440.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQEASV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            16409..16822
                     /gene="rpsL"
                     /locus_tag="VYR58_000207"
     CDS             16409..16822
                     /gene="rpsL"
                     /locus_tag="VYR58_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV3621441.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16842..17312
                     /gene="rpsG"
                     /locus_tag="VYR58_000208"
     CDS             16842..17312
                     /gene="rpsG"
                     /locus_tag="VYR58_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV3621442.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            17737..19818
                     /gene="fusA"
                     /locus_tag="VYR58_000209"
     CDS             17737..19818
                     /gene="fusA"
                     /locus_tag="VYR58_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV3621443.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            19922..24313
                     /locus_tag="VYR58_000210"
     CDS             19922..24313
                     /locus_tag="VYR58_000210"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV3621444.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            24415..24678
                     /locus_tag="VYR58_000211"
     CDS             24415..24678
                     /locus_tag="VYR58_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV3621445.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            24671..24949
                     /locus_tag="VYR58_000212"
     CDS             24671..24949
                     /locus_tag="VYR58_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV3621446.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            24970..25122
                     /locus_tag="VYR58_000213"
     CDS             24970..25122
                     /locus_tag="VYR58_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621447.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            25144..26385
                     /locus_tag="VYR58_000214"
     CDS             25144..26385
                     /locus_tag="VYR58_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV3621448.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            26395..26625
                     /locus_tag="VYR58_000215"
     CDS             26395..26625
                     /locus_tag="VYR58_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV3621449.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            26893..27615
                     /locus_tag="VYR58_000216"
     CDS             26893..27615
                     /locus_tag="VYR58_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV3621450.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            27832..29166
                     /gene="pepC"
                     /locus_tag="VYR58_000217"
     CDS             27832..29166
                     /gene="pepC"
                     /locus_tag="VYR58_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV3621451.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(29222..30133)
                     /locus_tag="VYR58_000218"
     CDS             complement(29222..30133)
                     /locus_tag="VYR58_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV3621452.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(30157..30960)
                     /locus_tag="VYR58_000219"
     CDS             complement(30157..30960)
                     /locus_tag="VYR58_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV3621453.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(30988..31977)
                     /gene="manX"
                     /locus_tag="VYR58_000220"
     CDS             complement(30988..31977)
                     /gene="manX"
                     /locus_tag="VYR58_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV3621454.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(32211..33230)
                     /gene="adhP"
                     /locus_tag="VYR58_000221"
     CDS             complement(32211..33230)
                     /gene="adhP"
                     /locus_tag="VYR58_000221"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV3621455.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKGKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(33569..34381)
                     /locus_tag="VYR58_000222"
     CDS             complement(33569..34381)
                     /locus_tag="VYR58_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV3621456.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKETIKKVAEKGHQIIITTG
                     RPYRMSKDFYHELGLNTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVRRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPENQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            34571..35989
                     /locus_tag="VYR58_000223"
     CDS             34571..35989
                     /locus_tag="VYR58_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV3621457.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGILL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFKDLKTIFGAALGSEGLGALISDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTSIGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLASLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQAK
                     DVHVMIWILDALFILNYISMAL"
     gene            36094..36801
                     /locus_tag="VYR58_000224"
     CDS             36094..36801
                     /locus_tag="VYR58_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3621458.1"
                     /translation="MIKKNIWDEVLNRGKWLIIFLVGLLFSQFPLALATFLTSRKFPL
                     LQTGLLVGALSLVVLTVFIIGARKTQLASFGLSFFKAKDLARLALSYLVILAFNILGV
                     VLLHLMNETTTSNQSNINDLVQNSSLISSFFLLLLIAPICEEILCRGVIPKKLFRGKE
                     NVGYIVGAIIFALLHLPTNLPSLLIYGGMSTVLTWTVYKTQRLEMSILLHMIVNGIFF
                     CLLALVVILSRTLGISV"
     gene            36895..37875
                     /gene="folP"
                     /locus_tag="VYR58_000225"
     CDS             36895..37875
                     /gene="folP"
                     /locus_tag="VYR58_000225"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV3621459.1"
                     /translation="MMKSLEGVTDMSTKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTWKSQVAEAALAAGANLVNDITGLMGDEKMARVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQAFTEEELADFETLPIEDLMDAFFERALARANQAGIAQENILLDLGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            37877..39199
                     /locus_tag="VYR58_000226"
     CDS             37877..39199
                     /locus_tag="VYR58_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV3621460.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKNMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMADY
                     QSLLEGEAVANLQSTTEFEIITALAYDYFAAEQVEVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVSHQKSVVTGEVFDYTSVVRQGRFQTGLLGLHQIENAGMAIALLDTFCQE
                     HGRELASNDLLGQALEETSWPGRLEVVSRDPLMILDGAHNPHAIKALLATLQERFADY
                     RKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFDDSRATDESVLEEAAKSRNLNYQG
                     WQDFLEQKLTDKKEEKKTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            39180..39734
                     /gene="folE"
                     /locus_tag="VYR58_000227"
     CDS             39180..39734
                     /gene="folE"
                     /locus_tag="VYR58_000227"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV3621461.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMEYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            39893..40705
                     /gene="folK"
                     /locus_tag="VYR58_000228"
     CDS             39893..40705
                     /gene="folK"
                     /locus_tag="VYR58_000228"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV3621462.1"
                     /translation="MDQLQIKDLEIFAYHGLFPSEKELGQKFVVSAILFYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETTEDLIETVAYKLVERTFEAYPLVQEMKLELKKPWA
                     PVHLPLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRNQGIHILKESSVLTT
                     EPWGGVEQDSFANQVVEVETWLPAPVLLESLLAIESEMGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYNALKQ"
     gene            complement(40751..41068)
                     /locus_tag="VYR58_000229"
     CDS             complement(40751..41068)
                     /locus_tag="VYR58_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV3621463.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            41425..41871
                     /gene="rplM"
                     /locus_tag="VYR58_000230"
     CDS             41425..41871
                     /gene="rplM"
                     /locus_tag="VYR58_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV3621464.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            41891..42283
                     /gene="rpsI"
                     /locus_tag="VYR58_000231"
     CDS             41891..42283
                     /gene="rpsI"
                     /locus_tag="VYR58_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV3621465.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(42545..42967)
                     /locus_tag="VYR58_000232"
     CDS             complement(42545..42967)
                     /locus_tag="VYR58_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV3621466.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAFGEFALQSLKQ"
     gene            43114..43290
                     /locus_tag="VYR58_000233"
     CDS             43114..43290
                     /locus_tag="VYR58_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621467.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            43691..45904
                     /locus_tag="VYR58_000234"
     CDS             43691..45904
                     /locus_tag="VYR58_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV3621468.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(46126..46602)
                     /locus_tag="VYR58_000235"
     CDS             complement(46126..46602)
                     /locus_tag="VYR58_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV3621469.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQR
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINTFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            46825..50028
                     /locus_tag="VYR58_000236"
     CDS             46825..50028
                     /locus_tag="VYR58_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV3621470.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNREKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            50408..50793
                     /gene="tnpA"
                     /locus_tag="VYR58_000237"
                     /pseudo
     CDS             50408..50793
                     /gene="tnpA"
                     /locus_tag="VYR58_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(51172..51801)
                     /locus_tag="VYR58_000238"
     CDS             complement(51172..51801)
                     /locus_tag="VYR58_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV3621471.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(51811..52812)
                     /locus_tag="VYR58_000239"
     CDS             complement(51811..52812)
                     /locus_tag="VYR58_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV3621472.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(52843..53484)
                     /locus_tag="VYR58_000240"
     CDS             complement(52843..53484)
                     /locus_tag="VYR58_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV3621473.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEILAK"
     gene            complement(53503..54318)
                     /locus_tag="VYR58_000241"
     CDS             complement(53503..54318)
                     /locus_tag="VYR58_000241"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV3621474.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGEANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            54589..55023
                     /locus_tag="VYR58_000242"
     CDS             54589..55023
                     /locus_tag="VYR58_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV3621475.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            55035..56225
                     /locus_tag="VYR58_000243"
     CDS             55035..56225
                     /locus_tag="VYR58_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEV3621476.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            56236..56727
                     /locus_tag="VYR58_000244"
     CDS             56236..56727
                     /locus_tag="VYR58_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV3621477.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            56742..57521
                     /locus_tag="VYR58_000245"
     CDS             56742..57521
                     /locus_tag="VYR58_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV3621478.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            57508..58326
                     /locus_tag="VYR58_000246"
     CDS             57508..58326
                     /locus_tag="VYR58_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV3621479.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            58326..58619
                     /locus_tag="VYR58_000247"
     CDS             58326..58619
                     /locus_tag="VYR58_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV3621480.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            58641..60542
                     /locus_tag="VYR58_000248"
     CDS             58641..60542
                     /locus_tag="VYR58_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV3621481.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLIDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKGYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            60602..61603
                     /locus_tag="VYR58_000249"
     CDS             60602..61603
                     /locus_tag="VYR58_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV3621482.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(61713..62048)
                     /locus_tag="VYR58_000250"
     CDS             complement(61713..62048)
                     /locus_tag="VYR58_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621483.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(62059..62301)
                     /locus_tag="VYR58_000251"
     CDS             complement(62059..62301)
                     /locus_tag="VYR58_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621484.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(62317..62511)
                     /locus_tag="VYR58_000252"
     CDS             complement(62317..62511)
                     /locus_tag="VYR58_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3621485.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWKEDF"
     gene            62677..63627
                     /gene="rsmH"
                     /locus_tag="VYR58_000253"
     CDS             62677..63627
                     /gene="rsmH"
                     /locus_tag="VYR58_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV3621486.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            63639..63956
                     /gene="ftsL"
                     /locus_tag="VYR58_000254"
     CDS             63639..63956
                     /gene="ftsL"
                     /locus_tag="VYR58_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV3621487.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            63960..66212
                     /gene="pbpX"
                     /locus_tag="VYR58_000255"
     CDS             63960..66212
                     /gene="pbpX"
                     /locus_tag="VYR58_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV3621488.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVIEQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPSGEYFNSSELKIADATIRDWDVNDGLTTGGMMTFLQGF
                     AHSSNVGMSLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAMSAF
                     GQGISVTQTQMLRAFTAIANDGVMLEPKFISALYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMILVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAEIADEKNGGYLVGST
                     NNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFTNPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKATAETFAKWLNIELEFEGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            66214..67194
                     /locus_tag="VYR58_000256"
     CDS             66214..67194
                     /locus_tag="VYR58_000256"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV3621489.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLVLQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            67803..69908
                     /locus_tag="VYR58_000257"
     CDS             67803..69908
                     /locus_tag="VYR58_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV3621490.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQNKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLNPFFRPELLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            70369..70704
                     /locus_tag="VYR58_000258"
                     /pseudo
     CDS             70369..70704
                     /locus_tag="VYR58_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(70771..71253)
                     /locus_tag="VYR58_000259"
     CDS             complement(70771..71253)
                     /locus_tag="VYR58_000259"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV3621491.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(71348..72832)
                     /locus_tag="VYR58_000260"
     CDS             complement(71348..72832)
                     /locus_tag="VYR58_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV3621492.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            72985..74592
                     /locus_tag="VYR58_000261"
     CDS             72985..74592
                     /locus_tag="VYR58_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV3621493.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPMQEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            74757..74924
                     /locus_tag="VYR58_000262"
     CDS             74757..74924
                     /locus_tag="VYR58_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV3621494.1"
                     /translation="MKKRILSAGLTFTSALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(74917..75426)
                     /locus_tag="VYR58_000263"
                     /pseudo
     CDS             complement(74917..75426)
                     /locus_tag="VYR58_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            75677..77122
                     /gene="cps4A"
                     /locus_tag="VYR58_000264"
     CDS             75677..77122
                     /gene="cps4A"
                     /locus_tag="VYR58_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV3621495.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSLSVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKLSQNTDLT
                     VDQSSSYLVAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALSFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIIDSLQDSIQTNMPLETMIDLVNAQLESGGTYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            77124..77855
                     /locus_tag="VYR58_000265"
     CDS             77124..77855
                     /locus_tag="VYR58_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV3621496.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLGKKRIPTLNDS
                     RYALIEFSMNTLYRDIHSALNKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRVQYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            77864..78556
                     /gene="cpsC"
                     /locus_tag="VYR58_000266"
     CDS             77864..78556
                     /gene="cpsC"
                     /locus_tag="VYR58_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEV3621497.1"
                     /translation="MQDQNTLEIDVFQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPATSPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     gene            78566..79249
                     /gene="cps4D"
                     /locus_tag="VYR58_000267"
     CDS             78566..79249
                     /gene="cps4D"
                     /locus_tag="VYR58_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4D"
                     /protein_id="HEV3621498.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVIQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILVTATGEANKRDVQKVKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GSYGNYGKK"
     gene            79265..80632
                     /locus_tag="VYR58_000268"
     CDS             79265..80632
                     /locus_tag="VYR58_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV3621499.1"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETEVERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGHLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMIYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDVGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGPAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            80663..81835
                     /locus_tag="VYR58_000269"
     CDS             80663..81835
                     /locus_tag="VYR58_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV3621500.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTAFQQDKAIQYYVACMR
                     ENSAKSGTTEDVFEHNGAICYNVDVPNIGPARAIVYDIAAINRAIKIAKENKDEDPIF
                     YILACRIGPFIHGIKKKIQAIGGTLLVNPDGHEWLRAKWSAPVRRYWKISEGLMVKHA
                     DLLVCDSKNIEKYIQEDYKQYQPKTTYIAYGTDTTRSILKSSDEKVRSWFKEKNVSEN
                     EYYLVVGRFVPENNYESMIRGFLASNSKKDFVLITNVEQNKFYNQLLAKTGFDKDPRV
                     KFVGTVYEQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     QSAIYWKKDELSQVIEKVEQFDAKMIDELDRQSNQRIADSFTWEKIVTDYEKVFKG"
     gene            81841..82737
                     /locus_tag="VYR58_000270"
     CDS             81841..82737
                     /locus_tag="VYR58_000270"
                     /inference="COORDINATES: protein motif:HMM:NF016852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEV3621501.1"
                     /translation="MAVKLKYDKSDITFLDDDELKKYQSELLKMISDVFTFFDENRIA
                     YSLSGGSILGAIRHKGFIPWDDDVDINIPRESYDKLFSLFELDNSLSRKYYLQSAKSH
                     PELGLHVSQIRKKGTVARRKYDHSAEECGISIDLYIVENVYNNPVKRFFQGYTSMFLT
                     FALASVRETKNHALMKEMFRLEGRKLNYSAGKLMVGWFFGIIPIEKWLNWLDKCNSSC
                     KDSHTKYVSIPTGRKHFRRETYLRENMNIYKKVPFETLMVNVPVWSEEYLEMFYGKDY
                     MVVPPVDKREQHLFLELSYGEE"
     gene            82738..83457
                     /locus_tag="VYR58_000271"
     CDS             82738..83457
                     /locus_tag="VYR58_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV3621502.1"
                     /translation="MKVAILTASGIGSRIGQDIPKQFIHVENKPVIIYTLEKFQNHPE
                     IDEICIVILKGWDQMVKAYAEQFGITKLKMITFGGKSGQESIYNGLREVKKAHPNDDV
                     TVLIHDGNRPLVSNDIISNALATYQQFGNAVAAIPTTEVVFVLENPQSTSSTEALNRD
                     LLRRTQTPHVYHLDNILSLHEKALENGITDVAASCQLMQLFGEKSYFSLGTEKNLKIT
                     TVEDLDIFKALLSSTRDKWIK"
     gene            83460..84515
                     /locus_tag="VYR58_000272"
     CDS             83460..84515
                     /locus_tag="VYR58_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HEV3621503.1"
                     /translation="MTLLLNKIYRQDVESSLETIVNINDLNGKSILITGASGLIGSSV
                     IDQLLLLNEIRNFNIKIFCCGREFESLEKRFGRQTEYLHFVFYDATKAPHFDFAVDYI
                     IHAASPASPELYVNQPVETMASNFLGMYNLLEYAKNAKVSNLVYISSSEVYGISTSNN
                     PLDENYIGTVDHLSVRSSYASSKRATETLCVSFASEYGIKIMIVRPGHIYGPSAKDSD
                     NRVSSFFMTEAIAGRDIVIKSTGSQLRSYCYSLDCASAILSVLLSGGSGQAYNVSNPN
                     SIITIKQMATCIADASGVRVLYDIPITQERKRENPMVNASLDSEKIESLGWSGLFSAE
                     VGFHHTFSILKELSSEK"
     gene            complement(84730..84909)
                     /locus_tag="VYR58_000273"
                     /pseudo
     CDS             complement(84730..84909)
                     /locus_tag="VYR58_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            85249..>86086
                     /locus_tag="VYR58_000274"
     CDS             85249..>86086
                     /locus_tag="VYR58_000274"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621504.1"
                     /translation="MIDGDFMNRRLVIKKKSIMFFMLMLCVTAFYGTNYWYTNIYIYD
                     FMIITSCLLSIIVFVCNGIRIDKTYYKGTIILGIVMWFSGLIAAQGKGLPAIVIFKES
                     LYTITPIMIFLAFRPMIKSIKDTSLFLRTISAAGVICNLIACIEMFFAKRGFDFLNIS
                     VFEKLRNGTPRFTIGETIIVLSFFISCSVVFSKGGKRNRRIFHVLNIALTAINLVYII
                     KTRTLNLYILSTLMMVPVLKKNVKKQLKFWIVFLISIILTFVSAEYFIPIVKNLIHSD
                     HGI"
BASE COUNT        25774 a        15572 c        19270 g        25470 t
ORIGIN      
        1 taaacttttt tcatcacaat ctcctaatga agccacccaa tcaggtggct tttttgcgtg
       61 gtgaggtgct ggtgatagaa attttttgca aaatagtaaa attttagaaa agttaagcta
      121 gttttaagtt tcgtcttgta tcatgtagtt attaaataaa gacctcctaa ctttatttaa
      181 taaaatccta aacttttctt tttcataata atctccctta acttcaccca atcaggtgga
      241 gttttttagc tctatttcag gcttttgggg actattctaa aaataatttt tcgatatttt
      301 tcggtatttt tcggattttg gtcggggaat tggcggggac ttttttagcg aatataacta
      361 agaaataggt ctgtggtcgc ttcagctagt tcaaactcaa tttgattgta agtgactgtt
      421 aattgaagaa ctggaactac tgtaataatg attttgcttg tctagtagtg gcgtattaaa
      481 tgagaagtaa catgtaagat tgtctcttcg tttacgaaat caaaatttct atgaaattga
      541 tagaatcctt aacgttctct taatcttaac cgtcttgtcg tacagcggtt gaagaaaatg
      601 taaacctttg acaaaattcg tgaactatgg gataataaaa aggaattgag tactagttct
      661 atatcatagg ctagaaaaga ccccaagctc acgaccaaat aagcttgagg tcttttttga
      721 cactatttgt ccttgtttag ccatttatcg actatacgaa gaacgacacc gaccacaatt
      781 ggtccgatga tagttttgag tactaattcc atcatgggct atctcacctc ctttcgtagg
      841 cggtgtagca gtgtcgtaga atattatacc acataagtgc taaacttagg agtcacccaa
      901 tcaggtggct tttttgtttg tggcttggtt ttttgatata atagagccat gagtagaatt
      961 ttagataatg agataatggg ggatgaggag ttagtagaac gcacgctccg tcctcagtat
     1021 ttacgtgaat atatcggaca ggataaggtc aaggaccagc tacaaatctt tattgaagct
     1081 gccaaaatgc gggatgaagc gctggatcat gtgctcttat ttgggcctcc aggtctcggg
     1141 aaaacgacca tggcctttgt tattgccaac gaactgggag tcaatcttaa gcagacgtcg
     1201 ggtccagtca ttgaaaaagc cggagatctg gtagctattt tgaatgagtt agagcctggg
     1261 gatgtacttt ttattgatga gatccatcgt ttgccaatgt cagtggaaga ggtgctttat
     1321 agtgctatgg aggacttcta catcgatatt atgattgggg ctggtgaggg tagtcgtagt
     1381 gttcatttgg agttaccacc ttttaccttg attggtgcga cgactcgggc tggtatgctc
     1441 tccaatccgc tacgggcacg ttttgggatt acaggccata tggagtatta tgcccatgct
     1501 ggcttgacag aaattgtcga gcggacggca gatatttttg agatggaaat cactcatgag
     1561 gcagcatctg agttggccct acgtagtcgt gggacccctc gtattgccaa tcgtctcctc
     1621 aagcgcgtgc gcgattttgc ccagataatg gggaatgggg taattgatga tattattacc
     1681 gataaggctt tgactatgct ggatgttgac catgaaggtt tggactatgt ggatcaaaaa
     1741 atccttcgta ccatgattga gatgtacagt ggaggacctg ttggtctagg aactctttct
     1801 gtgaatatcg ccgaagagcg tgagacagtt gaagatatgt atgagcctta cttgattcaa
     1861 aaaggtttta tcatgcggac acggtctgga cgggtggcga ctgctaaggc atatgagcac
     1921 ttaggttatg aatacagtga aaaataagca agaaatctta gaggctttta gagaaaatcc
     1981 agatatgatg gccattctga cgatcatccg agaccttggt ctgaaagact cgtggttggc
     2041 agcaggttct gtcagaaatt tcatttggaa tcttttgtca gacaaatccc cttttgatca
     2101 tgaaacagat atagatgtga ttttctttga tccagatttt tcttatgagg aaaccttatt
     2161 actggagaaa aagctgcgag aggattttcc tcagtaccag tgggaattga aaaatcaggt
     2221 ctatatgcat cagcacagtc ctcacactgc ttcctatacc agttctcgtg atgctatgag
     2281 taagtatcca gaacggtgta cgacagttgg actgcgcttg aatgaagaat cagattttga
     2341 actctatgca ccttatggtt tggaggatat tttgaatttt caagttcgtc caactcctca
     2401 tttcttagaa aatgaagacc gaatggaact ctatcaaaca cgtttatcca agaaaaattg
     2461 gcaggagaaa tggaaaaatt tgatttttaa aaatacttaa ggaaacttta agctagggag
     2521 tgtacactaa gttcataagt taagaagacc ttaacttaaa ctcctaaaac tttttcataa
     2581 taatctccct ataaaaataa agtcgcccaa tcaggcggct tatttttttg aaaaatgggc
     2641 ttggtgcctg agaataaata gcttagtgat agaagaaaat ggggaaatat ggtataatga
     2701 aacgatagat ttttgaatag gaataagatc atgtttggat tttttaagaa agataaggct
     2761 gtggaagtag aggttccgac acaggttcct gctcatatcg gcatcatcat ggatggcaat
     2821 ggccgttggg ctaaaaaacg tatgcaaccg cgagtttttg gacataaggc gggcatggaa
     2881 gcattgcaaa ccgtgaccaa ggcagccaac aaactgggcg tcaaggttat tacggtctat
     2941 gctttttcta cggaaaactg gacccgtcca gatcaggaag tcaagtttat catgaacttg
     3001 ccagtagagt tttatgataa ttatgtcccg gaactacatg cgaataatgt taagattcaa
     3061 atgattgggg agacagaccg cctgcctaag caaacctttg aagctttaat caaggctgag
     3121 gaattgacta agaacaacac aggattgatt cttaattttg ctcttaacta tggtggacgt
     3181 gctgagatta cacaggcgct taagttgatt tcccaggatg ttttagatgc caaaatcaac
     3241 ccaggtgaca tcacagagga attgattggc aactatctct ttacccagca tttgcctaag
     3301 gacttacgag acccagactt gattatccgt actagtggag aattgcgttt gagcaatttc
     3361 cttccatggc agggagccta tagtgagctt tattttacgg acaccttatg gcctgatttt
     3421 gacgaagcag ccttgcagga agctattctt gcctataatc gtcgccatcg ccgatttgga
     3481 ggagtttagg aggaaatatg acccaggatt tacagaaaag aaccttgttt gcagggattg
     3541 ccctggctat tttcctacca attttaatga ttgggggcct cttgcttcag atagcaatcg
     3601 gaatcatagc catgctagcc atgcatgaac ttttgaagat aagaggtcta gcgaccatga
     3661 cgatggaggg cctcttgact ctctttgcaa cctttgcatt aaccattccc ttggagaatt
     3721 acctgacttt tttgccagtt gatgggaatg tggttgccta tagtgttttg atttcaatca
     3781 tgttaggaac gaccgttttt agcaagtctt atacgattga ggatgcggtt ttccctcttg
     3841 ctatgagctt ctacgtgggc tttggattta atgctttact agatgctcgt gttgcaggtt
     3901 tggacaaggc tctcttagcc ttgtgtatcg tctgggcgac agacagtggt gcctatcttg
     3961 ttgggatgaa ctatgggaaa cgaaagttag caccaagggt atcgcctaat aaaacccttg
     4021 agggtgcctt gggtggtatt ttaggagcaa ttttagtaac cattatcttt atgatagttg
     4081 acagtacagt tgctcttcca tatggaattt acaagatgtc agtctttgct attttcttta
     4141 gcattgctgg acaatttggt gatttactag aaagttcgat caaacgtcat tttggtgtta
     4201 aggattctgg gaaatttatc cctggacatg gtggtgtttt ggatcgtttc gatagtatgt
     4261 tgcttgtatt tccaatcatg cacttatttg gactctttta atcaaaagac ggaggaaacg
     4321 ctatgctcgg aattttaacc tttattctgg ttttcgggat tattgtagtg gtgcacgagt
     4381 tcgggcactt ctactttgcc aagaaatcag ggattttagt acgtgaattt gccatcggta
     4441 tgggacctaa aatttttgct cacattggca aggatggaac ggcctatacc attcgaatct
     4501 tgcctctggg tggctatgtc cgcatggccg gttggggtga tgatacaact gaaatcaaga
     4561 caggaacgcc tgttagtttg acacttgctg atgatggtaa ggttaaacgc atcaatctct
     4621 caggtaaaaa attggatcaa acagccctcc ctatgcaggt gacccagttt gattttgaag
     4681 acaagctctt tatcaaagga ttggttctgg aagaagaaaa aacatttgca gtggatcacg
     4741 atgcaacggt tgtggaagca gatggtactg aggttcggat tgcaccttta gatgttcaat
     4801 atcaaaatgc gactatctgg ggcaaactga ttaccaattt tgcaggtcct atgaacaatt
     4861 ttatcttagg tgtcgttgtt ttttgggttt taatctttat gcagggtggt gtcagagatg
     4921 ttgataccaa tcagttccat atcatgcccc aaggtgcctt ggccaaggta ggagtaccag
     4981 aaacggcaca aattaccaag attggctcac atgaggttag caactgggaa agcttgatcc
     5041 aagctgtgga aacagaaacc aaagataaga cggcaccgac tttggatgtg actatttctg
     5101 aaaaggggag tgacaaacaa gtcactgtta cacccgaaga tagtcaaggt cgttaccttc
     5161 taggtgttca accgggggtt aagtcagatt ttctatccat gtttgtaggt ggttttacaa
     5221 ctgctgctga ctcagctctc cgaattctct cagctctgaa aaatctgatt ttccaaccgg
     5281 atttgaacaa gttgggtgga cctgttgcta tctttaaggc aagtagtgat gctgctaaaa
     5341 atggaattga gaatatcttg tacttcttgg caatgatttc catcaatatt gggattttta
     5401 atcttattcc gattccagcc ttggatggtg gtaagattgt gctcaatatc ctagaagcca
     5461 tccgccacaa accattgaaa caagaaattg aaacctatgt caccttggcc ggagtggtca
     5521 tcatggttgt cttgatgatt gctgtgactt ggaatgacat tatgcgactc ttttttagat
     5581 aatcgaggaa tattatgaaa caaagtaaaa tgcctatccc aacgcttcgc gaaatgccaa
     5641 gcgatgctca agttatcagc catgctctta tgttgcgtgc tggttatgtt cgccaagttt
     5701 cagcaggtgt ttattcttat ctaccacttg ccaaccgtgt gattgaaaaa gctaaaaaca
     5761 tcatgcgcca agaattcgaa aagattggtg ctgttgagat gttggctcca acccttctta
     5821 gtgcagaatt gtggcgtgaa tcaggtcgtt acgaaaccta tggtgaagac ctttacaaac
     5881 taaaaaaccg tgaaaaatca gactttatct taggtccaac tcacgaagaa acctttacag
     5941 ctattgtccg tgattctgtt aaatcttaca agcaattgcc actcaacctt tatcaaattc
     6001 agcccaagta tcgtgatgaa aaacgcccac gtaatggact tcttcgtaca cgtgagttta
     6061 tcatgaagga tgcttatagt ttccacgcta actatgatag tttggatagt gtttatgatg
     6121 agtacaaagc agcctatgag cgtattttca ctcgtagtgg tttagacttc aaggctatta
     6181 ttggtgacgg tggagccatg ggtggtaagg atagccaaga atttatggcc attacatctg
     6241 ctcgtacaga ccttgaccgc tgggttgtct tggacaagtc agttgcctca tttgacgaaa
     6301 ttcctgcaga agtgcaagaa gaaatcaagg cagaattgct caaatggata gtctctggtg
     6361 aagataccat tgcttactca agtgagtcta gctatgcagc taacttagaa atggcaacaa
     6421 acgagtacaa accaagcaac cgtgttgtcg ctgaagaaga agttactcgt gttgcaacgc
     6481 cagatgttaa atcaattgat gaagttgcag ccttcctcaa tgttccagaa gaacaaacga
     6541 ttaaaaccct cttctacatt gcagatggtg agcttgttgc agcccttcta gttggaaatg
     6601 accaactcaa cgaagtcaag ttgaaaaatc acttgggagc agatttcttt gacgttgcta
     6661 gcgaagaaga agtggcgaat gttgttcaag caggatttgg ttcacttgga ccagttggtt
     6721 tgccagagaa tattaaaatt attgcagatc gtaaggtgca agatgttcgc aatgcagttg
     6781 tcggtgctaa cgaagatggc taccacttga ctggtgtgaa cccaggccgt gattttactg
     6841 cagaatatgt ggatatccgt gaagttcgtg agggtgaaat ttccccagat ggacaaggtg
     6901 tccttaactt tgcgcgtggt attgagatcg gtcatatttt caaactcgga actcgctact
     6961 cagcaagcat gggagcagat gtcttggatg aaaatggtcg tgctgtgcca atcatcatgg
     7021 gatgttacgg tatcggtgtc agccgtcttc tttcagcagt gatggagcaa cacgctcgcc
     7081 tctttgttaa caaaacgcca aaaggtgaat accgttacgc ttggggaatc aatttcccta
     7141 aagaattggc accatttgat gtgcatttga ttactgtcaa tgtcaaggat gaagaagcgc
     7201 aagccttgac agaaaaactt gaagcaagct tgatgggagc tggttatgaa gtcttgacag
     7261 atgaccgtaa cgaacgtgtc ggtgttaaat ttagcgatag tgacttgatt ggtcttccaa
     7321 tccgtatcac tgttggtaaa aaagcggccg atggcattgt agaagttaag atcaaggcaa
     7381 ctggtgacac cattgaggtt catgcagata acgtgcttga aacgcttgaa atcctaagca
     7441 agaaataaaa actataatca gaagaaaaac aaggaaaaaa tgtaactagt ttttaccttg
     7501 ttttttctgt ataatgggag aaatgagtag ataaagaggt aaatgttatg ctaagatttc
     7561 caaaggattt tgtctgggga tcctctactt ctggaccgca gacagaagga cgtgtagctg
     7621 gtgacggtaa gggagacaat ctctgggatt actggttcca agtggagcca aatcgttact
     7681 ataatgggat tggttcagat aagacatcga ctttttatga aaattgggag cgggatattg
     7741 agcttttgtt agagactggt cacacagtct ttcggacttc tattcagtgg tcacggattt
     7801 ttccacaagg ctgtggaaaa gtcaaccctc aaggtgtgga tttttatcgt aaggtctttg
     7861 aggctattaa ggctaaagga attcgtctgt tagtcaatct ctatcatttt gatttacctt
     7921 ttgcccttca agaggatggt gatggttggg aaaataaggc gacagtctca gcctatgaag
     7981 actatgctcg tttttgtttt gagacttatg gagatttagt ggatcaatgg attaccttta
     8041 acgagcccat cgttcctgta gaatttggtt atttttatga tgcccattat ccacataagg
     8101 tggatgcaga ggcagctgtt aaggtagcct atcatacaca attggccagc agccgggctg
     8161 ttaaggcttg ccatgaactt ttgcctgatt ccaagattgg gattgtcctc aacttgacac
     8221 cggcttatcc acgtagccag catcctgctg atgtcaaggc agctcgtatt gcggcccttt
     8281 ttcaggccca atctttctta gatccatctg tcttggggac ttatccacag gagttggtag
     8341 aaatcttgca tgaacacggt cttttacctg atgctacaga ggaagagttg gaactcattc
     8401 gtgataatac ggtggacttc cttggtgtga actactatca acctttgcgt gttatggctc
     8461 ctcgatttgc taagcatcca gatagtccac tcttaccaga acatttttac gagccttatg
     8521 tgatgcctgg acgtaaaatc aattctcacc gtggttggga gatttatgag caagggattt
     8581 atgacatcgc ccaaaatatc aaggaaaatt atggcaatat tgagtggatg ttgactgaga
     8641 atggtatggg tgttgaaggg gaagaaaaat tccgtcaaga tggaatgatt caagatgatt
     8701 accgtattga ctttgtaaaa ggtcatcttc gtgaacttca ccgtgccatt gaagatggtg
     8761 ccaactgtaa gggctacttg atttggacct ttattgactg ctggtcatgg ctcaacagct
     8821 ataaaaatcg ctatggtttg gtcgaattag acttggaaac gcaagaacgt cgtctgaaga
     8881 aatcaggcca ctggttcaaa gaattaagcg ataataatgg attttaaaaa ggactctgac
     8941 tgattatccc aatcggtcag agttttttgc ttacaggagc ttaatttgaa ctataccaat
     9001 ttttactctt gacaagtgaa agaaacaagt atatactgtt tttgctgatt ctataaaaga
     9061 tgaattagac tataccaatt ttaaggagaa agcacagctt gcctgtgtcg tatatactat
     9121 gtgtggaatt gttggtgttg ttggaaacac aaatgcaact gatattttga ttcaagggct
     9181 tgaaaagctt gaataccgtg gctatgattc tgcgggaatt tttgtcctag atggtgctga
     9241 taaccatttg gtgaaggctg ttggtcgtat cgcagaattg tctgccaaga cagctggtgt
     9301 tgagggaaca actggtatcg gacatactcg ttgggcaact catgggaaac caacggaaga
     9361 caatgctcac ccacaccgct ctgagacaga acgttttgtc ttggttcaca atggggtgat
     9421 tgaaaactac cttgaaatta aagaagaata ccttgctggg caccacttca aagggcaaac
     9481 agatacggaa atcgccgtac atttgattgg aaaatttgcg gaagaagacg gtctctcagt
     9541 tcttgaagcc tttaaaaaag ctcttcatat tatccgtggt tcatatgcct ttgccttgat
     9601 tgactctgaa aatccagatg tcatctatgt agcgaaaaac aaatctccac ttttgattgg
     9661 tcttggggaa ggctacaata tggtctgctc agatgctatg gctatgattc gtgaaaccaa
     9721 ccaatacatg gaaattcatg accaagagtt ggtaatcgtc aaggctgata gcgtggaagt
     9781 tcaagactat gatggtaaca gtcgtgaacg tgctagctat actgcggaac ttgacttgtc
     9841 agatatcggt aagggaactt atccttacta catgcttaag gaaattgatg agcaaccaac
     9901 tgttatgcgt aaactcattc aagcctacac ggatgatgct ggtcaagtag tgattgatcc
     9961 tgctatcatt aaggctgttc aagacgcaga ccgcatctac atccttgcag ctggaacatc
    10021 ttaccatgca ggatttgctt ctaagaaaat gttggaagaa ttgacagata caccagttga
    10081 acttggcatc tcatctgagt ggggctacgg tatgccactt ctcagcaaga aaccactctt
    10141 catctttatc agccaatctg gtgaaacagc ggatagtcgt caagttttgg tcaaggctaa
    10201 tgaaatggga attccaagct taacagtgac aaacgttcca ggttcaaccc tctcacgtga
    10261 agccaactat accatgctcc ttcacgcagg tcctgaaatt gccgtggcat caactaaagc
    10321 ctatacagcg caaatcgcag cccttgcctt ccttgcaaaa gcagtcggag aagcaaatgg
    10381 taatgctaaa gcgcaagcct ttgacctggt tcatgaattg tcaatcgtag ctcagtctat
    10441 cgaatcaact ctttcagaga aagaaaccat tgaagccaag gttcgtgaac ttcttgaaac
    10501 aactcgtaac gccttttaca tcggacgtgg tcaagattac tacgtagcca tggaagcaag
    10561 tctcaaactc aaagagattt cttatatcca gtgtgaaggt tttgcggcag gagaactcaa
    10621 gcacggaacc attgccttga ttgaagaagg aacacctgtc ttggctctct tgtcagatcc
    10681 agtccttgcc aaccacactc gtggaaatat ccaagaggtg gcagcccgtg gtgctaaggt
    10741 cctcactatc gcagaagaaa atgttgctaa agataccgac gatatcgtcc ttacgactgt
    10801 acacccttac ctctcaccaa tttcaatggt cgtaccgacg caattggttg cttactttgc
    10861 aaccctccac cgtggcctcg atgtggataa accacgtaac cttgctaaat cagtaacggt
    10921 agaataagct aaaaaagtct agttatctag gctttttcta atgagcaaat tggttgcttg
    10981 tactcaagat tcgtgttaga ataatttttc aaattgaagg acagagatag acaaggagaa
    11041 tcacaatggt agaattggga atttcaacat ttggggaaat aacggagctt gaagggactg
    11101 gacaaactta cagtcatgct gaacgcattc gccagttggt ggcagagatt gagctggctg
    11161 acaaggttgg tttggacgta tatgggattg gcgagcacca tcgggcggat tttgcagtat
    11221 cagccccaga gattgtcctg gccgctgggg cagtcaatac caagaaaatc cgtttgacca
    11281 gtgcagtcag cattctgtca agcatggatc cgattcgttt gttccaacag tatgccacta
    11341 tcgatgcttt gtcaaatgga cgatcggaga ttatggctgg aaggggctct ttcacggaat
    11401 ctttccctct gtttggttat gacttgaaag actacgactc tctttttgat gagaaattag
    11461 acttgcttca gttagtcaat gaaaagacca agttagactg gcaaggtcga ttgactcaaa
    11521 cgattgctgg taaagaagtt tatcctcgtc cagttcagga caaattgccc ttgtggatag
    11581 ctacaggtgg tcatgtcgaa tcaacagtga agattgctca ggctggtcta ccgattgtat
    11641 atgctattat tggtggtaat ccacgttatt ttaaaaagtt gattcaggct tatcgtgaga
    11701 ttggaagcga agcgggccat gctgacaaag acttgaaagt gggagcccat tcttgggggt
    11761 ggattgcgga agatggtgag caggcggtga aagattattt ccatccgact aagcaagtgg
    11821 tggatgctat ttccaaagac cgtccgcact ggcaggaatt gcgttatgag caatatttgg
    11881 agcaggtagg gccaaatggc gccatgtttg ttggcaatcc agatcaggtg gccgaaaaat
    11941 tgattcgcat gatagaggat ttaggattgg accgcttcat gcttcatcta ccgcttggtt
    12001 ctatgcctca tgaccaggtt ctgagagcta ttgaactctt cggaacacaa gttgcaccca
    12061 aagtacgagc ttattttgct atgaaagagg cttaataaaa aatcctaatc aagtttatta
    12121 ggacaacaaa tattgtacaa aaattaatcc cccgagctat aatgcttggg ggatttttct
    12181 ataggagggc tagtttagtt ctctttttta ttttttagta agaaaccgag accaaggagc
    12241 gcaaggaggc tgattcctgc aaataggagt ttgttttcgt ttttgattcc tgtatttgga
    12301 agttcagctt gtttatctgg ggttgcaggt atattttcct tgctagagtt ttctaccgat
    12361 tcgtttcgaa ccgcttcttt tacagatgct tcttgtgctt cttgtgctgg ttgttcagct
    12421 tgtgaatcag ctgtagcttg gctaggttta ttttccgcat cagctacttt ggcatctggt
    12481 ttagtagaat caggtctagc ttctggagct gggtcttgat gtgcagggtg agaagcttca
    12541 ttttgatgtt caggcttgga aggggttgag tctggtttct cttctgcagt tgactcatgg
    12601 ctagttccat tttgagagac tcgaagaaca gtagctgtaa gggcattcaa tttcaagcct
    12661 ttttcagtcc attcaagtcc tttcgggttg gcaattccga ctgatcctgc ttggttttca
    12721 tctgccaaaa cttccgcatt tcttagatgt gcaaaggcag ttcccaaatt aaattcgcga
    12781 gctttttcat ccgcattgac aaagactgcg tagatatcac cgtttggagc agtgatttgg
    12841 tagccaatca ctacatcctc tttttccaca ccattttggc ctgggacagt gatgaggtgg
    12901 acacggtctt tgatatcttg aagactctta agtcggaagg catctgtaga ttgacgaagg
    12961 gcaatcaaac ctttcatata gtcacggctc ttgacatttt caggataagc tttaccatct
    13021 gtagccttag tccagtcaaa cttgttgact gcgtcgctag aatcgtaaga atcatggatg
    13081 aagtaaggat agtcaaatgg gttgccgtcc ttatcacgca acaagtgaga tttgtttgga
    13141 accttatcct ctgctactgg agtcttgtag gctgggtcac ggaattgttt agtacgtcca
    13201 tattcctgac cggagtggat aaatggagtt ccttgagctg tcaagaccat gagatttcca
    13261 agtcgtaaac gacggtggat ttcagcatag ttctcagcct tgcttgggtc ttttttgata
    13321 gactgggcaa tgatgtcaaa gagggtcaag ttatcatggg ctgcgatgta ttggatgaca
    13381 tctccagggc tgtcagcttc aaagttagtt ggttgagcaa tgagattttt aaagatggtg
    13441 ttgacatcac gcttgccacc tgtgataaag gcaggttgac cttcgtttgg ataaccagat
    13501 ttgaggttgt tacggatgtc atctgaaaag acagcgacag tatcggtatg tttcatccaa
    13561 tcttggtcag cagccttagt aggcatgttt tcatcaccgg cataggttct ccaaccttca
    13621 ccaagcatga tgaggtttgg attgagggcg cgtgcagcct tgtaagcttc ttcgatagaa
    13681 gcggcgtcat ggtctcccat catatcgaag cggaagccat ccactttgta ggtatcaact
    13741 aggtatttga tagagtcaac taggagccgt ttggtcatat ggtgggttgt ccccaagcgt
    13801 ccaccaccaa agctagttcg aggtgtgcca tcggcatcca taaagtggta gtagtttggc
    13861 tctaggtctt caaagatatc gactttggct gtgtggttat aaacgacatc taggatagct
    13921 cccataccac gtttgtggat ttcgttgatg aggtttttaa attctgcgat tcgtttttct
    13981 ggattcttag gatcgcttga gtacatacca gtcaaggaga agtagttttg agggtcatat
    14041 ccccagttgt agttgctgtt gcttgaagcg tagtcagaca agcgttcatg gtttttcaat
    14101 tcattgacaa agtagtaaga caagactgga aggagctgga tatgggttac acccaagtct
    14161 ttgagatagt ctagtttttc aatgaaggct tcaaaagtcc caaatggttt ggtcaagtct
    14221 tttgcaatgg caggatctga agtgaagtca cgcacatgag cttcgtagat aacggcgtct
    14281 tcacgagtct tgaaattgtg aatcttacca taagtcaagt cttgaggtcc gagtttagct
    14341 ggatctacaa aggcggcttt agccacttta tgggcatcgt caattttggc atcgtcgcta
    14401 ttccaagcag caagagattt agcgtaagga tcgagtgcaa gaacagtttt accttgacgc
    14461 tcgatttggt attgataata gtagccagtg aaatctgtga ttccgagttt gtttgtgctg
    14521 tctagagttt gtttccaagt tcctctttcc cctttttcga gagcgacagt tccaactact
    14581 ttgtcagggt cattcttgtc gtagacaaca acagaaacct tatcagcact tggtgaccaa
    14641 agggtcaaat caacttgttt tccttcttct tttaggtcag ctcccagttt gccatcatag
    14701 ctgtatgtct catctttcag gcgccagctt gttttggtag tgaattggtc ggaattgtag
    14761 ctaacagtat aaggatgttt tgtgtcagag aaatctccgc tgtaggtcac tttcttacca
    14821 gcttcatcga ttgcaacatc ggtaatagtt accttgtttc ctaggtgatt agtgatgttg
    14881 gagtgtttga ggatatcttc ttttttagca ccgacaagtg ttgaaaagct actttcaatg
    14941 ctagaagtgc ctacgtgttg ggctcctgtc atacggatat catggacata gtatggattt
    15001 gtgtaaatcg attcatcatc gtcttttagg aaaatttggc tatgattttt caaatctgtg
    15061 aacttataat tttctttacg gattttcacg tcgtctcctt gtttgctctc atctagtaat
    15121 aaaaatccaa attctcttgc ggcttcatta agaggaatgt cgatatagcg gccatatttg
    15181 cctgtagccg taaagtctgt tccgtcaggc cattgagcgc tacttggatt ttttacatct
    15241 ccccagtacc agagagattt cttgtcatag ttgccatctg tgcggtagta gttgacgcga
    15301 acagttcctg caggctgtgg ctcgtaagag aaaaccttgt aatcttggtc taaccaagcc
    15361 tcgttcattt ttggaactag tttttctaca gatttatcgc cggttagatt ttttccagct
    15421 gtattgttga tgaggaagct aattttcttg gcttgttctc cctttaattt gacatctagg
    15481 taatagccgt agtcatcttt cttggcatcc ttgaaggaca aagctccgtt tggccagttt
    15541 tcagatggtt tttcaacatc gtcccaagtc catagtcctt gagcatcctt gttttcttca
    15601 ggaagttttt tgacatggat acggaagtag ttatcttcga tgggctcttc tgccttagtt
    15661 tcagttgtta ctggactagt agaagtagtt ggctctgttg caggtttttc ttctgttttc
    15721 tctagggaag cgtttgcatt tctaggtgaa gaaatatcac tttcgttctt accagagcca
    15781 gctgctgtat cagtaagagg ttgggcaagg gtggttgtat ttctgttgtt gggttcgtta
    15841 gtggttggtg tactttcgtc ggatgagata gttggtgtag ccatggcaag caagacaagg
    15901 cttgcgccga taaggacaga accagttcca tttttgaggg aacggatgct gtagaccatt
    15961 tttttctcag tgtgagatgg tgtttttctc ataatgattc tccaatcaat aaatttctat
    16021 atcagtatag catgtagtaa aacaatatgc aagcgttttc tttgatttgt gaaaaaaatt
    16081 cttacttttg agaagttttc tgtactattt tatatatcag tataaatgac ggagataaaa
    16141 atgtcacata agccaagccg tattattagg aagatgatgt gttcccagct atttttattc
    16201 agaaattgat ctctaacatt accaataaaa aagaaaaata tcttgacaag caagggaaaa
    16261 ttttgttaca ataatagacg gtacttttta cttttggtct ctcaagagtg tacagggacg
    16321 tgctgacaaa tgttgcaaaa gtacacacag atgatatctg tcaccaagtg tatcatcacc
    16381 aaaaataaaa aaacacagga gaatgtagat gcctacaatt aaccaattgg ttcgcaaacc
    16441 gcgtaaatca aaagtagaaa aatctaaatc accagctttg aacgttggtt acaatagtca
    16501 taaaaaagtt caaacaaacg tttcttcacc acaaaaacgt ggtgttgcaa ctcgtgttgg
    16561 aacaatgaca cctaaaaaac ctaactcagc ccttcgtaaa ttcgctcgtg tacgtttgag
    16621 caaccttatc gaagttactg cctacatccc aggtatcgga cacaacttgc aagagcacag
    16681 cgtggtgctt cttcgcggtg gacgtgtaaa agaccttcca ggggtacgtt accatatcgt
    16741 ccgtggtgca cttgatactg caggtgttaa cgatcgtaaa caaggccgtt ctaaatacgg
    16801 tactaaacgt ccaaaagcat aaggaaaggg gataaagaga aatgagtcgt aaaaatagag
    16861 ctccaaaacg tgacgtattg ccagatccgc tatacaattc acaactagtt actcgtctta
    16921 tcaaccgcgt tatgcttgat ggtaaacgtg gtactgctgc ttcaatcgtt tacggtgctt
    16981 ttgagcaaat caaagaagct actggcaacg atgcacttga agtatttgaa acagctatgg
    17041 aaaacatcat gcctgtactt gaagtacgtg cacgtcgtgt tggtggttct aactaccaag
    17101 tcccagttga agttcgtcca gaacgtcgta caacacttgg acttcgttgg ttggtaacaa
    17161 tcgctcgtct tcgtggtgaa cacacaatgc aagaccgtct tgcaaaagaa atcttggatg
    17221 ctgctaacaa cactggtgca gcagttaaga aacgtgaaga tactcaccgt atggctgaag
    17281 ctaaccgtgc attcgcacac ttccgttggt aagataggat gcgaaagcgt taagaaagtc
    17341 ccagagaaaa tagggaatcg aagcaggttg cggttgcaac caatgagatt catctttttc
    17401 tccagacttt tagcttgagc tcaactaaat catgatgcta ggcacggtaa ggatgcaagg
    17461 tgaaaatagg aaactgacgc agtattcaac gaatacaagg agttttatct ttttcacgca
    17521 gcatcccgtt ccagctcaca tcggctaact aactttagcc tgggttcaaa ttagctaaat
    17581 cgattagtat tagctataac tcagcttacc atctcgtaag ttgaaaccaa caatagcatg
    17641 aaaacattga gaacgggtag gtcctgccta tccgttttta ttaaaatcgt gttataatag
    17701 aatagaaatc aaaaataaat aggagaaaca aacctcatgg cacgcgaatt ttcacttgaa
    17761 aaaactcgta atatcggtat catggctcac gtcgatgccg gtaaaacaac aactactgag
    17821 cgtattcttt actacactgg taaaatccac aaaatcggtg aaactcacga aggtgcgtca
    17881 caaatggact ggatggagca agagcaagaa cgtggtatca cgatcacatc tgctgcgaca
    17941 acagctcaat ggaacaacca ccgcgtaaac atcatcgaca caccaggaca cgtggacttc
    18001 acaatcgaag tacaacgttc tcttcgtgta ttggatggtg cggttaccgt tcttgactca
    18061 caatcaggtg ttgaacctca aactgaaaca gtttggcgtc aagcaactga gtacggagtt
    18121 ccacgtatcg tatttgccaa caaaatggac aaaatcggtg ctgacttcct ttactctgta
    18181 agcacacttc acgatcgtct tcaagcaaat gcacacccaa tccaattgcc aatcggttct
    18241 gaagatgact tccgtggtat cattgacttg atcaagatga aagctgaaat ctatactaac
    18301 gaccttggta cggatatcct tgaagaagac atcccagctg aataccttga ccaagctcaa
    18361 gaataccgtg aaaaattgat tgaagcagtt gctgaaactg acgaagaatt gatgatgaaa
    18421 tacctcgaag gtgaagaaat cactaacgaa gaattgaaag ctggtatccg taaagcgact
    18481 atcaacgttg aattcttccc agtattgtgt ggttcagcct tcaaaaacaa aggtgttcaa
    18541 ttgatgcttg atgcggttat cgactacctt ccaagtccac ttgacatccc agcaatcaaa
    18601 ggtattaacc cagatacaga cgctgaagaa actcgtccag catctgacga agagccattt
    18661 gcagctcttg ccttcaagat catgactgac ccattcgtag gtcgtttgac attcttccgt
    18721 gtttactcag gtgttcttca atcaggttca tacgtattga atacttctaa aggtaaacgt
    18781 gaacgtatcg gacgtatcct tcaaatgcac gctaacagcc gtcaagaaat cgacactgtt
    18841 tactcaggtg atatcgctgc tgccgttggt ttgaaagata ctacaactgg tgactcattg
    18901 acagatgaaa aagctaaaat catccttgag tcaatcaacg ttccagaacc agttatccaa
    18961 ttgatggttg agccaaaatc taaagctgac caagacaaga tgggtatcgc ccttcaaaaa
    19021 ttggctgaag aagatccaac attccgcgtt gaaacaaacg ttgaaactgg tgaaacagtt
    19081 atctcaggta tgggtgaact tcaccttgac gtccttgttg atcgtatgcg tcgtgagttc
    19141 aaagttgaag cgaacgtagg tgctcctcaa gtatcttacc gtgaaacatt ccgcgcttct
    19201 actcaagcac gtggattctt caaacgtcag tctggtggta aaggtcaatt cggtgatgtg
    19261 tggattgaat ttactccaaa cgaagaaggt aaaggattcg aattcgaaaa cgcaatcgtc
    19321 ggtggtgtgg ttcctcgtga atttatccca gcggttgaaa aaggtttggt agaatctatg
    19381 gctaacggtg ttcttgcagg ttacccaatg gttgacgtta aagctaagct ttatgatggt
    19441 tcatatcacg atgtcgactc atctgaaact gccttcaaga ttgcggcttc actttccctt
    19501 aaagaagctg ctaaatcagc acaaccagct atccttgaac caatgatgct tgtaacaatc
    19561 actgttccag aagaaaacct tggtgatgtt atgggtcacg taactgctcg tcgtggacgt
    19621 gtagatggta tggaagcaca cggtaacagc caaatcgttc gtgcttacgt tccacttgct
    19681 gaaatgttcg gttacgcaac agttcttcgt tctgcatctc aaggacgtgg tacattcatg
    19741 atggtatttg accactacga agatgtacct aagtcagtac aagaagaaat tattaagaaa
    19801 aataaaggtg aagactaatc cgtcctcact ctagaaggaa gtcacttagt ggcttccttt
    19861 tgtctttaga aaatacctct aaatatggta aaatagtaga agaataatgt gaggaaaatg
    19921 aatgtcaaat agttttgaaa ttttgatgaa tcaattgggg atgcctgctg aaatgagaca
    19981 ggctcctgct ttagcacagg ccaatattga gcgagttgtg gttcataaaa ttagtaaggt
    20041 atgggagttt catttcgtat tttctaatat tttaccgatt gaaatctttt tagaattaaa
    20101 gaaaggtttg agcgaagaat tttctaagac aggcaataaa gctgtttttg aaattaaggc
    20161 tcggtctcaa gaattttcaa atcagctctt gcagtcctac tatagggagg ctttctctga
    20221 aggtccatgt gctagtcaag gttttaagtc cctttatcaa aatttgcaag ttcgtgctga
    20281 gggtaatcag ctatttattg aaggatctga agcgattgat aaggaacatt ttaagaagaa
    20341 tcatcttcct aatttagcca aacaacttga aaagtttggt tttccaactt ttaactgtca
    20401 agttgagaag aatgatgtcc tgacccaaga gcaggaagag gcctttcatg ctgaaaatga
    20461 gcagattgtt caagctgcca atgaggaagc gctccgtgct atggaacaac tggagcagat
    20521 ggcacctcct ccagcggaag agaaaccagt ctttgatttt caagcgaaaa aagctgcagc
    20581 taaacccaag ctggataagg cggagattac tcctatgatc gaagtgacga cagaggaaaa
    20641 tcgtctggta tttgaagggg ttgtttttga tgtggagcaa aaagtgacta gaacaggtcg
    20701 tgttttaatc aactttaaaa tgacggacta tacttcaagt ttttctatgc aaaagtgggt
    20761 taaaaacgag gaagaggccc agaagtttga cctcatcaag aagaattctt ggctccgagt
    20821 tcgagggaat gtggagatga ataacttcac acgcgatttg actatgaacg tacaggatct
    20881 gcaggaagtt gttcactatg agcggaagga tttgatgcca gaaggtgagc gtcgggttga
    20941 gtttcatgct catactaaca tgtcgactat ggatgctttg ccagaggtcg aagagattgt
    21001 tgcaacagct gctaagtggg gacacaaggc ggttgctatc acagaccatg ggaatgtcca
    21061 gtcctttcca catggctata aggcggctaa gaaagcggga atccagctga tctatgggat
    21121 agaagccaat atcgtggagg accgtgtccc tatcgtctat aacgaagtgg agatggactt
    21181 atcagaagca acctacgtgg tctttgacgt ggaaacgacg ggactttcag ctatctataa
    21241 tgacttgatt caggttgcgg cctctaagat gtacaagggg aatgttattg ctgaatttga
    21301 tgaatttatc aatcctgggc atcccttgtc agcttttact acagagttaa ctggaattac
    21361 agatgatcat gtcaaaaatg ccaaaccact agaacaagtt ttgcaagaat tccaagaatt
    21421 ttgcaaggat acggtcctag ttgcccacaa tgctgccttt gacgttggct ttatgaatgc
    21481 taattatgag cgtcatggtc ttccaaagat tagtcagcca gttattgata cgctggagtt
    21541 tgctagaaac ctctatcctg agtataaacg ccatggtttg gggcctttga ccaagcgttt
    21601 tggtgtggcc ttggaacatc accacatggc caactacgat gcggaagcga ctggtcgtct
    21661 gcttttcatc tttatcaaag aggtagcaga aaaacatggt gtgaccgatt tagctagact
    21721 caacattgat ctaatcagtc cagattctta caaaaaagct cggatcaagc atgcgaccat
    21781 ctatgtcaag aatcaggtag gtctaaaaaa tatctttaag ctggtttcct tgtctaatac
    21841 caagtatttt gaaggagtgc cacggattcc gagaacggtt ctagatgccc atcgagaggg
    21901 cttgatttta ggttcagcct gttcagaggg tgaagttttt gacgtggtcg tttctcaagg
    21961 tgtggatgcg gcggttgagg tggccaagta ttatgacttt atcgaggtca tgccaccggc
    22021 tatctatgcg cccttgattg ctaaagagca ggtcaaggat atggaggaac tccagaccat
    22081 tatcaagagt ttgatagagg ttggagaccg ccttggcaag cctgttttgg ctacgggaaa
    22141 tgttcactat atcgaaccgg aagaagagat ttatcgtgaa attatcgtcc gtagtttggg
    22201 acagggtgcg atgattaacc gaactatcgg tcatggtgaa catgcccaac cagcaccact
    22261 tccaaaggct cattttcgaa cgactaatga gatgttggat gaatttgcct ttttgggaga
    22321 ggaactggct cgtaaactgg ttattgaaaa caccaatgcc ttggcagaaa tatttgaacc
    22381 cgttgaagtc gttaagggtg acttgtatac gcctttcatc gacaaggctg aagaaacagt
    22441 tgctgagttg acctataaga aagcttttga gatttatgga aatccgctgc cagatattgt
    22501 tgatttgcgg attgaaaaag aattaacatc catactgggg aatggatttg ctgtgattta
    22561 tctggcatcg cagatgctgg tgcaacgttc taatgaacgg ggttatttgg ttggttctcg
    22621 tgggtctgtc ggatctagtt tcgttgcgac catgattgga attacggagg tcaatcctct
    22681 ctctcctcac tatgtctgtg gtcagtgtca gtacagtgag tttatcacag atggttcgta
    22741 cggttcagga tttgatatgc cccataagga ctgtccaaac tgtggtcaca aactcagtaa
    22801 aaacggacag gatattccgt ttgagacctt ccttggtttt gatggggata aggttcctga
    22861 tattgacttg aacttctcgg gagaagatca gcctagcgcc cacttggatg tgcgtgatat
    22921 ctttggtgaa gaatatgcct tccgtgcggg aacagttggt acggtagctg ccaagactgc
    22981 ctatggattt gtcaagggtt acgagcgaga ttatggcaag ttttatcgtg atgcagaagt
    23041 agaacgcctc gctcaaggag cggcgggtgt caagcggaca acaggccaac acccgggggg
    23101 aatcgttgtt attccgaact acatggatgt ctacgatttt acgcctgtcc agtatccagc
    23161 agatgatgtc acggctgaat ggcagaccac tcactttaac ttccacgata tcgatgagaa
    23221 cgtcctcaaa ctcgatgtac tgggacatga tgatccgacc atgattcgaa aacttcagga
    23281 tttgtctggt attgacccta ataaaattcc tatggatgac gaaggcgtga tggcactctt
    23341 ttctgggact gatgtgctag gggtaacacc tgaacaaatt ggaacgccta cgggtatgtt
    23401 ggggattcca gagtttggaa caaatttcgt acgtggaatg gtagacgaaa cccatccgac
    23461 aacctttgcg gaattgcttc agctgtctgg tctgtcccac ggtactgatg tttggttggg
    23521 gaatgctcag gatctgatta agcaaggaat agcggaccta tcgactgtta tcggttgtcg
    23581 ggacgacatc atggtttacc tcatgcatgc gggtctggaa cctaagatgg cctttaccat
    23641 tatggaacgg gtacgtaagg gtttgtggct aaagatttca gaagaggaga gaaatggcta
    23701 tatcgaagca atgaaggcta ataaggtgcc agagtggtat atcgaatcct gtgggaaaat
    23761 taagtacatg ttccctaagg cccatgcggc agcctacgtt atgatggcct tgcgtgtagc
    23821 ttacttcaag gttcaccatc ctatttatta ctactgtgct tacttctcca ttcgtgctaa
    23881 ggcttttgat atcaagacca tgggtgcggg cttggaggtc atcaagcgca gaatggaaga
    23941 aatctctgaa aaacggaaga acaatgaagc ctctaatgtg gaaatcgatc tctatacaac
    24001 tcttgagatt gtcaatgaga tgtgggaacg aggtttcaag tttggtaaat tagatctcta
    24061 ccgtagtcag gcgacagagt tcctcatcga cggggatacc cttatcccac catttgtagc
    24121 aatggatggt ctgggagaga acgttgccaa gcaactggtg cgggcgcgtg aagagggaga
    24181 attcctctct aaaacagaac tacgcaagcg tggtggactc tcatcaacct tggttgaaaa
    24241 gatggatgag atgggtattc ttggaaatat gccagaggat aaccagttga gtttgtttga
    24301 tgagttgttt taaaaaattg cttaataatc tattaaaaga ggctaacgta tatccaatag
    24361 atttacatta gctttctttt ttgttaaaat agtctatgga aagagggtga gagtatgtca
    24421 aagatgagta taagcatccg tctggatagt gaggttaagg agcaggccca acaggtgttt
    24481 agtaatctgg gaatggatat gacaacagct attaatattt tccttcgtca ggcaattcaa
    24541 tatcagggat taccttttga tgttagacta gacgaaaatc ggaagttgct ccaagcgtta
    24601 acggatttag accaaaatcg taatatgagc cagtcttttg aatcagtctc agatttgatg
    24661 gaggacttac gtgcttaaga ttcgttatca taaacagttt aaaaaagatt ttaagttggc
    24721 tatgaagcgt ggtttgaagg cagaattatt agaagaagtt ttgaattttc tggttcaaga
    24781 aaaagaacat cctgccagat atcgtgatca ttcattgacg gcatccaagc attttcaagg
    24841 agttcgtgaa tgccataccc agccagattg gcttttggtt tataaagtag acaagtcgga
    24901 attgatttta aatttgctga ggacaggcag tcacagtgat ttattttaat ctattttaag
    24961 ggggttctca tgaaactaag aatatttgcg gaagataagc cggctaagaa ggtatttgaa
    25021 tatcaattag aacttgctga tcgtacaatt cttctatcga cagcactctt gtcaggtgct
    25081 attgctttag caggaatctt ttctgctttg aaagaaaaat aaaaatagaa aagagaaaac
    25141 agaatggttt taccaaattt taaagaaaat ctagaaaaat atgcgaaatt gttggttgcg
    25201 aacggaatta acgtgcaacc tggtcacact ttggctctct ctattgatgt ggagcaacgt
    25261 gaattggcac atctaatcgt gaaagaagct tatgccttgg gtgcgcatga ggtcatcgtt
    25321 cagtggacag atgatgtgat taaccgtgag aaattcctcc atgccccgat ggagcgtttg
    25381 gacaatgtgc cagaatacaa gattgctgag atgaactatc ttttggagaa caaggctagc
    25441 cgtcttgggg ttcgttcatc tgatccaggt gccttgaacg gagtggacgc tgacaagctt
    25501 tcagcttctg ctaaagctat gggacttgcc atgaagccta tgcgtatcgc aactcaatct
    25561 aacaaggtta gctggactgt agcagccgct gctggacttg agtgggctaa gaaagtcttc
    25621 ccaaatgctg cgagcgacga agaagcagtt gatttccttt gggatcaaat cttcaaaact
    25681 tgtcgtgtct acgaagcaga tcctgttaag gcttgggagg aacatgcagc cattctcaag
    25741 agcaaggccg atatgcttaa taaggagcaa ttttcagccc ttcactacac agcgccagga
    25801 acagatttaa cacttggttt gccaaagaac cacgtttggg aatcagctgg tgctgtcaat
    25861 gcacagggcg aagaattctt gccaaatatg ccgacagaag aggtcttcac agcgcctgac
    25921 ttccgtcgtg cagatggtta tgtcacttct acaaaaccgc ttagctacaa cggaaatatc
    25981 attgaaggca ttaaggtgac ctttaaggat ggacaaatcg tagatatcac tgctgagaag
    26041 ggtgatcagg ttatgaaaga ccttgtcttt gaaaatgcgg gtgcgcgtgc cttgggtgaa
    26101 tgtgccttgg taccagatcc aagtccaatt tctcagtcag gcattacctt ttttaacacc
    26161 cttttcgatg aaaatgcgtc aaaccacttg gctatcggtg cagcctatgc gactagcgtt
    26221 gttgatggag cggagatgag cgaagaggag cttgaagctg cagggcttaa ccgttcagat
    26281 gttcacgtag actttatgat tggttctaac caaatggata tcgatggtat tcgtgaggat
    26341 ggaacgcggg tacctctttt ccgtaatggg aattgggcaa attaaggaga taatatgtta
    26401 ggaagtatgt tcgttggtct cctagtggga tttttagcag gtgctatgac caatcgtgga
    26461 gagcgaatgg gatgttttgg aaaaatgttt ctcggttgga tcggagcctt tctaggtcac
    26521 ttgctctttg gaacttgggg gccagtttta tcaggaacag ctattatccc agcgatttta
    26581 ggagccatga ttgttttagc tattttttgg agacgaggaa gttaatttcc taaatctgat
    26641 actcaatgaa aatcaaagag caaactagga aactagccgc aggttgctca aagcactgct
    26701 ttgaggttgc agatagaact gacgaagtca gctaaaaaca ctgttttgag gttgcagata
    26761 gaactgacga agtcagtaac atatatacgg caaggcgacg ttgacgcggt ttgaagagat
    26821 ttttgaagag tatgaaacga aaaggaggtt ggtcattgta ctagcctcct tttgatatga
    26881 tataatagtt ctatgagatt agataaattt ttagttgcct gtgcggtggg aagtcggact
    26941 gaggtcaaaa acttgctcaa ggctgggcgc gtgactgtaa atggtaaaaa agaaaaatca
    27001 gctaaattgc agattgatga aaaaatagat gagattcgct ttgatgggca agtgttggag
    27061 tatgaagagt ttgtctacta catgatgaac aagcccaaag gagttatctc agcgactgag
    27121 gatcccaagc acagaaccgt tctggacttg ttggatgact tggcgcggag taaggaagtt
    27181 ttcccagtag gacgcttgga tattgacacg catggtcttt tgctcttgac caatgatggt
    27241 cagctggctc atgttcttct ttcgcccaag cgtcatgtgg acaagactta tctggcacaa
    27301 gtcaagggaa tcatgaccca agaagatgtg gagacatttg ctgagggtat tcctctcaaa
    27361 gactttacct gtcaacccgc tatactggag cttgtatcca tagatacaga aaagaatcaa
    27421 agccaaatcc gtgtgaccat tgcagaaggg aagtttcatc agatcaagcg tatggtgggc
    27481 tactgtggca aggaagtggt ggacttgcaa cgattgacta tgggaacttt agtattagat
    27541 gagaacctgg aacgagggga atggcgtcgc ttgaccaagg aagaattaga aattctccgc
    27601 gctaatatta tttaatttag tttaatactc aatgaaaatc aaagagcaaa ctaggaaact
    27661 agccgcaggc tgtacttgag tacggcaagg cgacgttgac gtggtttgaa gagattttcg
    27721 aagagtataa attcgaaaaa ggtgagggac aatgtcctcg ccttttatgt tttttagttg
    27781 cttcctttgt gaaaagagtt ataatagact gtagaataaa aggaggaatc tatgaacgcg
    27841 attcaagaat catttactga taaactattt gccaactatg aagcaaatgt aaaataccaa
    27901 gcgattgaaa atgctgccag ccacaacgga atttttgcag ctctggaacg tcgccaaagc
    27961 catgtagaca acacacctgt tttctcattg gatttaacca aggacaaggt cactaaccag
    28021 aaagcgtctg gtcgttgctg gatgtttgcg gctctcaaca ccttccgcca caaactcatc
    28081 tcgcaataca aattggagaa ctttgagttg tcacaagccc acactttctt ctgggataag
    28141 tatgagaaat caaactggtt cttggagcaa gtcattgcga cttcagacca agaattgact
    28201 agccgcaagg ttagcttctt actccaaaca cctcaacaag atggcggtca atgggatatg
    28261 gtcgtttccc tctttgaaaa atacggtgtc gtgcctaagt cagtttatcc tgagtctgtt
    28321 tcatctagca gcagtcgtga gctaaatgcg atccttaata aattgcttcg tcaagatgct
    28381 caaatcttgc gtgacttgct tgtttctggt gcagatcaag cgactgttca agctaagaaa
    28441 gaagacctct tgcaagaaat ctttaacttt cttgctatgt cattaggact tccaccacgc
    28501 aagtttgact ttgcttatcg cgataaagat aacaactaca aaagtgaaaa aggaatcaca
    28561 ccacaagagt tttacaagaa atatgtcaat cttcctttag aagactacgt ttctgttatc
    28621 aatgctccaa ctgctgataa accttacgga aaatcttaca cagttgagat gttggggaat
    28681 gtggttggta gccgtgcagt tcgttacatc aacgttccaa tggagcgctt gaaagaattg
    28741 gcgattgccc aaatgcaagc aggtgagact gtttggtttg gttctgatgt cggccagctc
    28801 agtaaccgta aggctggcat ccttgcgaca gatgtttatg actttgaatc aagcatggac
    28861 attaaactta ctcaagacaa ggctggacgt ttggactata gcgaaagctt gatgacccac
    28921 gccatggtct tgacaggtgt tgacttggac gaaaatggta aatcaaccaa gtggaaggtt
    28981 gaaaactcat ggggagacaa ggtcggtaca gatggttact ttgttgcctc agacgcttgg
    29041 atggacgaat acacatacca aatcgttgtt cgtaaggaat tgctgacagc agaagaacaa
    29101 gctgcctatg gagcagaacc aattgtactt gcaccatggg atccaatggg agccttggct
    29161 gaataaaagc atagaaaaaa ggaatcagat tttagaacct ggttcctttt tagttgcttg
    29221 attacatgat gtgaagaaca tgtgccacaa tacccactgc gaagagggca aggataatag
    29281 tgattggaga tacttttttc ttaagtaagt acatgcaaag taaagtaagg agtagtcctg
    29341 ataatccagg aatcaacata tccaagtttt gttggaaagt agtaactttt tcaggagttt
    29401 gagacaatcc ttgtcctact tgtgcgaatg cttcttggat acctttagac ccttctggca
    29461 atttatccca atggatataa gccttttcat ctagttgaac tttagaaaca tcgaaagcaa
    29521 atttaatatt tacccagcgt tgaacaagga cagcaagaat gaacatccca aggatagaag
    29581 ctcctttagt gatatcttga aggataccac cagacatatc tttagtgatt tctgatccag
    29641 ccttgtatcc aatctcttga acataccaca agaatgacat acgaatcaag ttccatgcaa
    29701 caaagaagag gagtggaccc aagatattgc cagtaagggc aagtgaagca ccgagagatc
    29761 caaggattgg gcgtactgta aaccagaata ctgggtcacc gataccagca agaggtccca
    29821 tcataccgat tttgacccct tggatagcag cgtcatcgat ttccacaccg ttagcacgtt
    29881 cttcttcaag cgcaagagta acccccatga ctggagcagc tacgtatgga tgagtgttga
    29941 agaactcaag gtgacgctca agagcagcga tttgatcttc ttttttagta tagagttttt
    30001 tgatagctgg aatgagtgta taagcccagc ccaagttttg catccgttca aagttccaag
    30061 acccttgtaa gaaggttgaa cgccaccaaa cttttttacg atctgattta gttaattgaa
    30121 gtttttcagt catgatgttt tcagtccttt cttatcttag tagtcttcta ggatatcgcc
    30181 gattgggtcg ttagaagttg cggctcctcc gccaccattt ccaccagttt tagaaaggtg
    30241 aaggtagata agagcgatag caacaccgat agcaccgaat ccgattagag taatatctga
    30301 cacagcagcg agaacgaaac caagagcgaa gaatggccat acttcacgag ttgccatcat
    30361 gttgataacc atggcgtaac caacggcaac gaccatacca ccaccgatag ccataccatc
    30421 tttgagccag tctggcatgg cactaaggat actttgtaca gtttcagttg gtaccataag
    30481 gagaagagct gcaggaagcg cgatacgaag tccttggaag agtagcgcaa tgaaatgcgc
    30541 acgctccaca gcgccgaagt cacctttttt agcggcagca tctgcagtat gaaccaaacc
    30601 aactgaaatt gtacgaacaa tcattgtcaa gaaaagtcca gctacggcaa gagggatagc
    30661 aaccgcttgg gcaacaccga taccagtctt ggtaaagtca ccaccaagaa ccatgataat
    30721 ggcagcagcg acagaagcaa gtgcagcatc aggagcgata gcagcaccga tatttgacca
    30781 accaagggca atcatttgaa gcgatccacc gaggataatc cctgcttcca agtgacctgt
    30841 tacaagccca ataagggtac aggctacaag tggttggtga aattggaact ggtcgaggat
    30901 gccttcaaga cctgcaaaga aggctacaac gactactaaa accatagaaa taatagacat
    30961 gtttaaaatc ctttcataaa taatggctta tttgacattg gctttgttaa tcaagtcaaa
    31021 caaatctttt ttagaatcat ttggtacttt acggacatca aattcaacac ccaagtcacg
    31081 cattttttca aatgtcgcaa catcttcttt gtccatagac aaaacggtat tgaccaatgt
    31141 tttacctgtt gagtgagcca tagaaccaac gttaagagtc ttgattggca cgccgccttc
    31201 gatggcacga agggcatctt gaggtgtttc aaacaagata agggcatgtg tttctccaaa
    31261 acgtgggtct tttgaaatct caatcagttt ttgaattgga accacgttag ccttgacatt
    31321 acctggagct gcttgtttaa tcaattcttt acgaaggtcg tctttagcca cgttatctga
    31381 agcaacgatg atacgatttg cttttgaatc tggagtccaa gcagttgcaa cctgaccgtg
    31441 aagtagacgt gtgtcaagac gggcaagatt gattttcaat ttaccgtctc cgataacagt
    31501 tccttctggg atagcagctt gggcaactgg agcagctgca gcgcttgcaa cttcttcaac
    31561 tggatttagc tcttctggaa gagctttgat gccatccttg gcttctttaa tgatattagc
    31621 agcgactttt tctacacctg cagcagcgtc catgaggcgc tctgtgtagg cttgaatcaa
    31681 catcggtaag ttaagtcctg tgatgatggc aaacttacgc tcaggatttt ctcccatcac
    31741 gcgactagct tggttaaatg gagaaccact ccaaaggtca gccaaaacta gaacctcatc
    31801 ttctgcgtca aatgcagcaa cagcgttatt aaacttagcg tatagatcat caggaccttc
    31861 atttggcata aaggtcacaa cttgaacctt ttcttgttca ccaaagatca tagatcctga
    31921 ctgatgaata cccgcagcaa attcgccgtg gctcgcaata atgattccga tactcattat
    31981 tgtcattcct ccttttttgt tttagttttc atttaagaaa actttaagac tgtttaagta
    32041 taaaccgttt tcataaaaaa agcaactatt tatcataaaa aattaaaaaa tttttatttt
    32101 tatatgttga tatgttgagt ttttaaggag taatcttgaa ttcttattta aaaatttaat
    32161 ataaaaaagt tagaagaagc ttccaacttt taaaataggt ttctattaga ttagtgggtg
    32221 aagtcgagta ccatacgtcc ttggatttga cctttttcca tttcgtcgaa aatggcaaca
    32281 gcatcttcta ctggacgttt ttgaacaact ggggctacca gaccttctgc accaaattgg
    32341 aaggcttctt ctaagtcttt acgagttccg acaagagaac cgatgacttg gattccatcg
    32401 aggactgttt taacgatact gagttccatc atttcagaag gaagaccaac agcgacgacg
    32461 cgaccaccag cacgaacgga gtcaacagcc tggttgaagg caactttaga cacagcagtt
    32521 acgacagctg aatgagctcc tccatcagtt tttcctttaa tgagtccagc tacatcttca
    32581 acttcgaggc cgttaatcac aatgtcagcg cctacttctt ttgcaagggc aagtttgtca
    32641 ttgttgatat cgactgcgat aacatgagca ttgaatactt ttttagcgta ttgaacagcg
    32701 aggttaccaa gtccaccagc accgtaaaga acaacccatt ggcctggttc aacttttgct
    32761 tctttgatag ctttataggt tgttactcca gcacatgtga tagaagaagc ttgggctgga
    32821 tcaagtccgt caggaacctt gacagcatag tcagcagtta cgatacattg ttcagccata
    32881 ccaccgtcta ctgagtagcc agcatttttc actgtacggc aaagggtttc gcgaccagtt
    32941 gtacagtatt cgcaagtgcc gcatccttca aagaaccaag caacgctgac gcggtcaccg
    33001 actttaaggc ttttcacatc tggagcaatc tctttaacga taccgatacc ttcgtgccca
    33061 agaacacgtc ctgggacttg accaaagtca ccatgagcaa cgtggagatc ggtgtggcaa
    33121 acgccacagt attcaacttc tacaagtgct tccccagttt caagtggacg gagtactttt
    33181 tcttcaatag caacaccagt gctttctgga tttacaacaa cagctttcat agctatcctc
    33241 cttgatattg accgagaaca gggacaacgg gactggattg attttttgtc aacagagtcg
    33301 agtgtgacga gctctcttgt atttatatgt gaagtatatc acaaaagaaa gccttttcca
    33361 aggttttgga gacaaaaagt agaacaatcg attaactggt tgatgagact gtgaaaagag
    33421 cacaaagacc agcttgcaag ctggtcatac tcttcgaaaa tctcttcaaa ccacgtcagc
    33481 ttcatctaca acctcaaagc agtgctttga gcaacctacg gctagcttcc tagtttgctc
    33541 tttgattctc attgagtatc agtataggtt ataagaataa gtcttgtagg gttttggcaa
    33601 ccccatcttg gtcgttggta agggaaattt gctcatctgc ataagggagt agctctggat
    33661 tggcattttt catggcataa cccttcccag caaaagcgag catttcggta tcattgtgtt
    33721 catctccaaa ggcaatcaaa tcttttttgt cacgattcat tatcttgagc aagtagtcca
    33781 aagcaaaggc cttgttgaca ccttttgggg tacattcaag gatattgagc ggacctcccc
    33841 aggtattgat agacagttga tgctggtaga aggcgttcat ttcttttgcc agagcatatt
    33901 tgtcactggc tctagtctgt aacagaatac agttaggatc cttggttact aactcaggct
    33961 gaaattgatt ttcaggctgg aaagcttcta caccaaatag tttgggatta gcaatttctt
    34021 cattgggatt tgtaatgtaa aattttttac ggtattctcc agcgataaaa tcggcttgaa
    34081 tgtcctctga acgtcgaacc atgtctagca gatatttttt gtctacagtt aaacactttt
    34141 caaaatccca aacttggtct ggtaaatgag taagggagcc gttgaaatta atcataggag
    34201 tgtttaagcc tagttcatgg taaaaatctt ttgacatgcg gtaagggcga cccgtcgtaa
    34261 taataatctg atggcctttt tcagcaactt ttttaatggt ttctttggta aagtcagaaa
    34321 tttgactgtc tgagttgagc agggttccat ccaggtcaac tgcaataatt tttttcgtca
    34381 tagggacctt tctagtgtct tttcagataa gatgtctact attataacag aaagcaggca
    34441 gaaaagcaga ttcgaaacaa aaaaagaaat ttcatcaaat tcttaaataa atcaaacaaa
    34501 gatattgaaa aagtgaatga taaatgatat aattctatta ttgttcgtaa aaattaaaag
    34561 gagattgata atggacaaat tatttaaact aaaagagaac ggtacagacg ttcgtacaga
    34621 ggttctcgct ggtttaacaa ctttctttgc aatgagctat attctctttg taaacccaca
    34681 aattctttcg caaacaggaa tgcctgctca gggtgtattc ctcgcaacga ttattggtgc
    34741 agttgctggt accctgatga tggccttcta cgctaactta ccttatgccc aagcgccagg
    34801 tatgggactc aatgccttct ttacctttac agttgtattc ggacttggtt attcttggca
    34861 agaagcccta gctatggtct tcatctgtgg aattatctca ttgattatta ccttgacaaa
    34921 tgttcgtaaa atgatcattg aatcgattcc caatgctctt cgctcagcta tttcagctgg
    34981 tatcggtgtc ttccttgcct atgtagggat taagaatgct ggacttttga aatttacgat
    35041 tgatccaggt aactatactg ttgtaggaga aggggctgac aaagctcaag caacgattgc
    35101 agcaaactct tcagcagttc caggattggt cagctttaat aatccagctg ttttggtggc
    35161 tcttgcagga ctcgctatca caattttctt tgtcatcaaa ggaattaaag ggggaattct
    35221 cctctctatc ttgacaacaa ctgttcttgc tattgcagtt ggtttggtag atttgtcaag
    35281 catcgatttt gctaataacc atgttggtgc agcttttaaa gatttgaaga caatctttgg
    35341 tgcagctctt ggttcagaag gtttgggagc tttgatttca gatacagctc gcttgcctga
    35401 aactctgatg gctattcttg ccttttcatt gacagatatt tttgatacaa ttggtacctt
    35461 gatcggtaca ggtgaaaaag ttggtatcgt agcgacaaat ggtgaaaatc atcaatcagc
    35521 taagttagac aaggctcttt actctgactt gattggtact tcaattggtg ccatcgcagg
    35581 tacttcgaac gtaacgactt atgttgagtc tgctgctggt atcggtgcag gtggacgtac
    35641 tggtttgaca gccttggtcg tggcaatctg ttttgcgatc tcaagcttct ttagcccact
    35701 tctagcgatt gtaccaacag ccgctacagc tccaatcttg attatcgttg ggattatgat
    35761 gttggctagc ttgaaaaata tccattggga cgatatgtct gaagcggttc ctgctttctt
    35821 cacatctatc tttatgggat tcagctactc tatcactcaa gggattgcag ttggtttctt
    35881 gacttacact ttgactaagc ttgtcaaagg tcaagctaaa gatgttcatg tcatgatttg
    35941 gattttggat gctttgttta tccttaacta catcagtatg gcactataaa tgctataata
    36001 taaaaagggg ttctcccctt tttatattat agttacttga aaattgcttc aaactaggta
    36061 ggtgattttg attgaatggt aggagtataa ttgatgataa aaaagaatat ttgggatgaa
    36121 gtattaaaca gggggaagtg gttaataatc tttctagtag ggcttttgtt ttctcagttt
    36181 cctttagccc tagcaacttt tttaactagc agaaaatttc cactgcttca aacgggacta
    36241 ttagtagggg ccttatctct tgtggtttta actgtattta taataggtgc taggaaaaca
    36301 cagttggcta gttttggttt atcgtttttc aaggctaagg atttggctag attggcctta
    36361 agctatctag tgattcttgc ctttaatatt cttggtgtgg tcttactgca tttgatgaat
    36421 gaaacaacaa ccagcaatca atcaaatatt aatgatttgg tccagaatag ttccttaatt
    36481 tccagttttt tcttactgct tctaatagct cctatttgtg aggagatttt atgtcgagga
    36541 gtgattccta aaaaactctt tcgtggtaaa gaaaatgtgg gttatatagt cggtgctatt
    36601 atctttgcct tgcttcattt accgacaaat ctaccttctc ttcttatcta tggaggaatg
    36661 tcaactgtgc taacttggac agtttataaa acccaacgtt tggaaatgtc tatcttactt
    36721 cacatgattg ttaatggaat ttttttctgt ttgttggctc tcgtggtgat tttgagtcgg
    36781 acattaggga tctctgttta agatttttga caattgctta cttgtttctg ctgggaaaaa
    36841 gatgaatgca atcgtgtcca tctttttctt tttatggtaa aatagagaaa taatatgatg
    36901 aaaagccttg agggagtgac cgatatgtca actaaagcca atcatgcaaa gacagctatt
    36961 tgcggaatta tcaatgtaac cccagactcc ttttcggatg gtggtcaatt ttttgctctt
    37021 gagcaggcac tccagcaggc tcgtaaattg atagcagaag gggctagcat gctagatatc
    37081 ggcggagaat cgactcggcc gggaagtagc tatagctatg ttgagataga agaggaaatc
    37141 cagcgtgttg ttccagttat taaggctatt cgcaaggaaa gtgatgtcct catctctatt
    37201 gatacttgga agagccaggt agcagaggct gctttggctg ctggtgccaa tctagtcaac
    37261 gatatcactg gtctcatggg cgatgaaaaa atggctcgtg tggttgctaa ggctggagcg
    37321 aaagtggtta tcatgtttaa tccagtcatg gctcgtcctc agcatcctag ctcgctcatc
    37381 tttcctcatt ttggctttgg tcaagctttt acagaggaag agttagctga ctttgaaaca
    37441 ttgccaatcg aagacttgat ggatgctttc tttgaacgag cactagcgag agcaaatcaa
    37501 gctggaattg cacaagaaaa tatcctgttg gatctgggaa tcggctttgg tctgaccaag
    37561 aaagaaaatc tgcttctttt acgggacctg gataaactac atcagaaggg ctatccaatc
    37621 tttcttggag tgtcgcgcaa gcggtttgtc atcaatatcc ttgaagaaag tggttttgaa
    37681 gtcaatcctg agacagaact tggtttccga aatcgggaca cggcttcggc tcatgtaact
    37741 agtatcgctg cgagacaggg tgtagaagtg gtgcgcgtgc atgacgtagc tagtcacagg
    37801 atggcagttg aaattgcctc tgccattcgt ctggctgatg aagcggaaaa tttagattta
    37861 aaacaatata aataagatga aagaaattga aaataatcag tggattgcta actaccggac
    37921 ggatcaaccg cattttggct tggaacgaat ggtggaactg ttagccttgc gtggaaatcc
    37981 ccatctcaaa ctcaaggtca tccatatcgg agggactaac ggcaagggtt cgaccattgc
    38041 ttttttgaag aatatgctgg aaaagctagg gctgagagtt ggggtgttca gctcgcccta
    38101 tctcattcat tacacagacc agattagcat caatggggaa tccattccag aggctaggct
    38161 agaagccctc atggcagact atcagtcttt gctggaggga gaagcggtcg ccaatttaca
    38221 gagtacaacc gagtttgaga ttatcacagc cctggcctat gactactttg ccgcagagca
    38281 agtagaagtg gctatcatgg aagtcggtat gggtggactt ttagatagta ccaatgtctg
    38341 tcagcccatt ttgacaggaa ttacgactat tggcttggac catgtagccc tacttggtga
    38401 taccttggaa gccatagcag agcagaaagc tggtattatc aaacaaggta ttcccttggt
    38461 gacaggtcgt atcgctccag aagctttggc tgtgattgac cgcattgcgg aagggaaaga
    38521 tgcgccgaga cttgcctacg ggacagatta tcaggtcagc catcaaaaga gtgtggttac
    38581 aggcgaagtc tttgactata caagtgttgt caggcaaggt cgcttccaaa ctggcctgct
    38641 tggcttgcac cagatagaga atgctgggat ggccatagct ttacttgata ctttttgtca
    38701 agaacatggt cgagagctag caagcaatga cctgcttggt caagccttgg aagaaacaag
    38761 ttggccaggg cgtttggaag ttgtgtcgag agaccccctg atgattttgg atggagccca
    38821 caatccccat gcgatcaagg ccttattggc aaccttgcaa gaacgctttg cggattatcg
    38881 taaggaaatc ctctttactt gcatcaaaac caaggcctta gaggatatgt tggacttgct
    38941 gggggccatg ccagataccg agctaactct aacacatttt gacgatagtc gggcgactga
    39001 tgaaagcgtg ctggaagagg cggctaagtc tagaaatctc aactaccaag gttggcagga
    39061 ttttctagag cagaaattga cagataaaaa agaagagaaa aaaacagtta ggattgtcac
    39121 gggttccttg tatttcttga gccaagtgag agcctatctg atggagagga aaaacgaaaa
    39181 tggatacaca aaagattgaa gcagctgtaa aaatgattat cgaggctgtc ggagaggacg
    39241 ctaaccgtga gggcttgcag gaaacgcctg ctcgagtggc ccgtatgtac caagagattt
    39301 tttcaggtct tggtcaaaca gcggaggaac atttgtcaaa atcctttgag attattgatg
    39361 acaacatggt agtagaaaag gatatctttt tccacactat gtgtgagcac cacttcttgc
    39421 cattttatgg tagagcgcac atagcctata ttccagatgg tcgtgtggca ggtttgtcta
    39481 agctagcccg tacggttgaa gtttattcga aaaaaccaca aattcaagaa cgattgaata
    39541 tcgaagtggc cgatgccttg atggagtatc taggtgctaa aggagccttt gttgtcattg
    39601 aggcggaaca tatgtgtatg agcatgcgtg gtgtcagaaa accaggcact gcaaccttga
    39661 cgacagtagc tcgtggtcta tttgaaacag ataaggacct ccgagatcag gcttatcgtt
    39721 taatgggact ataatattct tcgaaaatca aattcaaacc acgtcagcct ccatctgcaa
    39781 cctcaaaaca gtgttttgag cagcctgcgg ctagcttcct agtttgcact ttgattttca
    39841 ttgagtataa aaagaatccg ctttgggcgg atttttcgag aaaggaatca ttatggatca
    39901 actgcagatt aaggatttgg aaatttttgc ctatcatggt ctttttccga gtgagaaaga
    39961 attggggcaa aagtttgtcg tttcagctat cctattctat gatatgacca aggcggcgac
    40021 agatttggat ttaacagcct ctgtccatta tggagaactg tgtcagcagt ggacgacttg
    40081 gtttcaggaa acaactgagg acttgattga aacggtagcc tacaaactag tagaacgtac
    40141 ctttgaggct tatcctcttg tccaagaaat gaagctggaa ctgaaaaaac cttgggcacc
    40201 ggtgcatttg ccactagata cttgctcggt aaccattcat cgccgcaagc aacgagcctt
    40261 tatcgcccta ggaagcaata tgggagataa acaagcaaac ttgaaacaag ccattgagaa
    40321 aatgcgaaat caaggtatcc atattctcaa agagtccagt gtcttgacga cggagccttg
    40381 gggtggtgtg gagcaagata gctttgctaa tcaagtggtt gaggttgaaa cctggctacc
    40441 ggcaccggtc ttgttagaaa gcttgttagc cattgagtca gagatgggac gggtgagaga
    40501 agtacattgg gggcctcgtt tgattgattt ggacttgctc tttgtggagg accagatcct
    40561 ttatacagat gaccttatct tgccccatcc ttacatagcg gaacgccttt ttgtccttga
    40621 gtccttacag gaaattgcgc ctcattttat ccatccgaca ttaaagcaac cgatccgcaa
    40681 cttgtataat gctttgaaac aatagaaaaa actctagttt tcagtagttt gtaactgaag
    40741 gctagagttt ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtcca
    40801 tgtctaaaac cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat
    40861 caatggctgt agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa
    40921 gcaattgaaa ctcgagttct tcttccaatt caaagacatt ttttaagaaa tggtcgataa
    40981 tataccaaaa agagtcaatg atgtcatcag gcaagctggt aacaatgcca aaactagcag
    41041 accgcatgtg ggtattggta aaagccatat ctctgtctcc tttcttttcc cttatcatac
    41101 agcaaatagg attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg
    41161 aaaaagaagg aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta
    41221 acttgattat ataactttca gttactttga gaagttaccg aaaaatattt ttcatatcta
    41281 ttgactttta ggggtgaaat ttggtatgat agtaggcggt attgtttacc ccatttgaaa
    41341 ggccccggaa ccttccaaat acttttcgat gggaaggaac acccatcacc gtaaacaaaa
    41401 atcgaactat atataggaga aatcatgaac aaaacaacat ttatggctaa accaggccaa
    41461 gttgaacgta aatggtacgt agttgacgca actgatgtac cacttggacg tctttctgca
    41521 gtagttgcta gcgtacttcg cggaaaaaac aaaccaacat ttacaccaca cactgataca
    41581 ggtgacttcg tgattgttat caatgctgaa aaagttaaat tgactggtaa aaaagcaact
    41641 gataaaatct actacactca ctcaaaccac ccaggtggat tgaaacaaat ctctgcaggt
    41701 gaacttcgtt ctaaaaatgc agtacgtttg attgagaaat cagttaaagg tatgcttcca
    41761 cacaatacac ttggacgcgc tcaaggtatg aagttgaaag tatttgttgg agctgagcac
    41821 actcatgctg cacaacaacc agaagttctt gacatttcag gacttatcta aggaaaggaa
    41881 caaataaagt atgtcacaag cacaatatgc aggtactgga cgtcgtaaaa acgctgttgc
    41941 acgcgttcgc cttgttccag gaactggtaa aatcactgtt aacaaaaaag atgttgaaga
    42001 gtacatccca cacgctgacc ttcgtcttgt catcaaccaa ccattcgcag ttacttcaac
    42061 tgtaggttca tacgacgttt tcgttaacgt tgtaggtggt ggatacgctg gtcaatcagg
    42121 agctatccgt cacggtatcg ctcgtgccct tcttcaagta gacccagact tccgcgattc
    42181 attgaaacgc gcaggacttc ttacacgtga ctcacgtaaa gttgaacgta agaaaccagg
    42241 tcttaagaaa gctcgtaaag catcacaatt tagtaaacgt taattcgaaa gaattactat
    42301 acttatacag agcacctttc ggggtgttct ttttttatac tttcttacta aattggtgca
    42361 attgacacag ttgttgcgac tttagtcgct tacaaatgtg gctgcaacct gacaaggtca
    42421 gttgcctcaa aacgttaatc aatacaatta tatcaacgtt tcaaagcact caagagttta
    42481 cctcatgggt gcttttttta tgttttttga aaaagttcac ctcaaagttt accttatttt
    42541 caccttattg ttttagagac tgtaaggcaa attcaccgaa ggccataggg actacattag
    42601 aagtattgac ataaatctgt gttgtacctg tgtcgctatg tattagagct tcagaaatgg
    42661 cttctaagct cattcctgct tgtttagcga gcgttgctcc ggtatgacgt agtttgtgtg
    42721 gcgtagcgtg tgtaagctct gggtgtcgtt ttctgatagt tttcatctta ttattgagat
    42781 agtcagaatg taaaggttta ttgatattgc ctttggtatc tatgtaagta aagatgaatt
    42841 gttctggatt actgatgata ccaaactttg ccagttcata tttttgttgt tttttccatg
    42901 aagtcagaag ttgaagtaag tcattagaaa tagagaaaat gggaaatgtt tccacaataa
    42961 aacgcatatt atcagatggt taatgcgttt tatatttggg tttgaggctt ataaaatagg
    43021 ataagcgtac tgaaaactta gatatgacaa acaaaataaa atttttaaaa gctacagaga
    43081 aacatggtat aatgtatcta aaggaggtag catatgtcct tagatataga taaagaaaag
    43141 atgacaatca tgggaatagc ttttgaaaac cgatccgttt ttaagagtgt ttggtatgct
    43201 ttaagtacaa atatgattga aggatggcga cctacggtta gtgatgttga aaaattacga
    43261 gatgaagctc ttgctctggg gatgacttaa tgaagcgcaa ctgttatgag tcttatgact
    43321 atgttgatcc ggataattta tataccgatc cgggttcttc agttctaaga aataagcagg
    43381 aaggaaaaaa gcacgtgagc ttgaatatcg tatgattgct agtaagagtt tgaaattatt
    43441 tatcaatcct atcttagtta atagtttaaa agtagtttgt ttcacaactg cataagctta
    43501 gaaaagttga aaagtgataa ctctttaata aactcttggt ttgttaaaag atattttgtc
    43561 cactacattt tttcaattga ctattatttg tcatagatat aacagataga acattgcatt
    43621 cagaataatg aaaaacgcat caaaaatggt gcgttctgtt tttatgctac cataaaagga
    43681 ggaaaacaaa ttgaaaattt ttaagggaga gttttatcga atctctgtat taacagacaa
    43741 gctagtaagg ttagaatact ctcgaactgg aaattttgag gatagaacga cacaacttat
    43801 ctataataga gattttggcc aaatttcgtt agattatatc gagacatcaa acgtactaga
    43861 tattatgacg gactattttc atctgcactt taataaagga gaatttaacg ccgaaaattt
    43921 atttatagaa ttaaaaggaa attttgccgt atatggtagt cgctggtatt ttggtgaatc
    43981 tattgaaacg ttaaaaggaa cagctcggac tctggataag gcagatggag caatctcgtt
    44041 agaagatgga attattagcc gaaatggtat agccttattg gatgattctc aaggatttat
    44101 ttgggatgaa caatctggtt atattgagag agaaaatcaa attgacctgt atttctttgc
    44161 ctatgggcat gattatagag gagcaatcag agacttttac catttgactg gttcaacacc
    44221 cttgttgcca agatatgctt taggcaattg gtggagtaga tattggcctt atacgtcgga
    44281 tgaatacttg gatttaatag acagatttga aacagagaaa attccattat ctatcggtgt
    44341 gttagatatg gattggcata taactgacat tccagctcgt tttggaagtg gctggacagg
    44401 atatagttgg aatagaaact taataccaaa tccagaacag ttattgcaac aacttcatga
    44461 tagaaagtta aaactctcct taaatgtcca tcctgctgat gggatacggg cttatgaaga
    44521 agcttatcct caaatcgcaa aacggttggg gttaaatgta gaactagaag aacctgctat
    44581 ttttgatttt tttaatccct cttttaggga agcctacttt aaagatgttc attatgagct
    44641 agaaaagcag ggagtagatt tttggtggat tgactggcaa caagggacac aaggtatgct
    44701 agatccactt tggcttttaa accattatca ctatcaggat agttgtaaaa atgcagaagg
    44761 tggtttgatt ttatcaagat atgcaggtcc tggtagtcac cgctaccctg ttggtttttc
    44821 aggggatact attattagtt ggaattcctt aaggtttcaa ccctatttta cagcgacagc
    44881 atctaatatc ggttatagtt ggtggagtca tgatatcggt ggacatatgt tgggggatta
    44941 tgacgaagag ctacaaacta gatggctaca gtttggtgtt tttagtccga ttactcgatt
    45001 acatagttct agaagtcctt ttaatagtaa agaaccttgg tttttttcag aaacaacatc
    45061 taagattatg aagaaatacc ttcgtttgag acatcagatg attccttatc tatataccat
    45121 gaatgtaaag acacatgagg aaggtgcccc attaatcagt ccaatctatt atttctatcc
    45181 agagaatgat gagagctata atgttccaaa ccaatacttt tttggaacag aactgatggt
    45241 ggctcccatt gtagaaaaga tggatttgac attccaatct gcaaaagtag atgtatggtt
    45301 ccctgaaggt gaatggtatg acttcttttc agagaaaaaa tacacaggtg gtgtgaagtt
    45361 aagtgtttat agggacatct cgactacgcc tgtgtttgca aaaagtggtg caatcattcc
    45421 cttggttggt tctgagatag gtatgggtgt tgatttacct gaggttgtag attggtatgt
    45481 attcccaggg aaacaacatt cttttgaaat gcttgaagat caaaatggtc aaagatataa
    45541 aacaagatta tcaatcgatt gggaaatggg aatggtagag ttagcattac aaggagattc
    45601 tagtatcgtt ccaagcaata gaaaacatag aattcatttt aaaggaacga atgtgtctat
    45661 aattgaattg ccaaataaga atgatacagc taaatttgaa tggaaagata ataaaaggac
    45721 atctttaaat gacgaagttt ttagactact aaagacagct tctcttccat atgaattaaa
    45781 agatagattg ttaaatcaat tcatcaatgc gaaaaactct catgacttaa tgaatatctt
    45841 gcatcatcag gataaggaat tgagagggcg tttgttggaa atgatattta ctagccaaaa
    45901 ctaattgaaa taattagaaa gtcatttgtt tagtgtatat gaagattctg tatggtattc
    45961 gttatcactg gtcacattga aaatgtgaaa taagcaccta caacatagac tttacaacac
    46021 ttcatgtttc atatcatggg gtgtttttct atttaagtca aagccaatca aaaaatctca
    46081 ctattcatca ggttaaagga aacctaatca tagtgagatt gtgaattata gtagagtttg
    46141 tatcgcctct tcaatttgtt ttgggtctgt ttttgaagaa aagcgttcaa agacttgccc
    46201 atcacgacca atgagaaact tagcgaaatt ccattcgatt cgttttccta gtgggccaga
    46261 tttatggtct tttaaccaga catagagagg gtctgcttcc ttaccgttga ccttaatctt
    46321 ggcaaaacgt gggaaggtgg tttgaaaatg taggctacag aaggtgttga tttcctctgc
    46381 gctgccgggt gcttgtccca taaactgatt gcaagggaaa tccaatattt cgaagccctg
    46441 atcttgatag cgttcataga gttcttgaag tctctggtac tggggcgtta aaccacatcc
    46501 agtagcagtg ttgacaatca agagaacttt gccacgatag ctatccaagg gagttgcttg
    46561 gttgttttgg ttcaaaacgg aaaaatcata aagtgaagtc atgagggcct cttttctttt
    46621 tctacattgt aacagttttt acttttttcg tcgagtcgga tggaagatat tgttgaagaa
    46681 taagccctca atatgataga aaccgtttac aaataacttt aaaaatggta tgatttaatt
    46741 aaaccggttt actttgttgc tataaatctc taatttgaga tttagttcct attgatttta
    46801 caatatgttt attggagtgt atacatgcaa acaaaaacaa agaagctcat tgtgagtttg
    46861 tcttcacttg ttttatcagg atttttatta aaccattata tgacagttgg agcggaagaa
    46921 acgactacga ataccattca gcaaagccag aaggaagttc agtatcagca aagggataca
    46981 aaaaatttag ttgaaaatgg tgattttggt cagacggagg acggaagcag tccgtggaca
    47041 ggaagcaaag ctcaggggtg gtcagcttgg gtagaccaga agaatagttc tgcagatgcc
    47101 tcaactcgag tcattgaggc taaggatggg gctatcacta tctcaagccc tgagaaatta
    47161 agggcagcgg ttcaccgtat ggttcctatt gaagctaaga aaaagtataa actgcgtttc
    47221 aagattaaaa cagataataa agtcgggatt gccaaggttc gtatcattga ggaaagtggt
    47281 aaggacaagc gattgtggaa ttctgcaacg acgtcaggaa caaaggactg gcagaccatt
    47341 gaagcagact atagcccgac tttagatgtt gataaaatca agctggagtt attctatgaa
    47401 acaggaactg ggactgtttc ctttaaggat attgagctgg tagaggtagc agcccagctt
    47461 tctgaggatt ctcaaacaga taaacagctt gaggaaaaga ttgatttacc aattggaaaa
    47521 aaacatgttt tttctcttgc ggactatact tataaggtag aaaatcctga cgttgcttca
    47581 gtcaaaaatg gaattttaga acctcttaag gaagggacaa ccaatgtcat tgtcagtaaa
    47641 gatggcaagg aagtgaaaaa gattcctttg aagattctag cctctgttaa ggatgcatac
    47701 acagcccgtt tggatgactg gaatggcatc atcgctggga atcaatacta tgattctaaa
    47761 aatgaacaga tggccaaatt aaaccaggaa ttggaaggaa aggtagctga tagcctatct
    47821 agtatttcaa gtcaggcgga ccgcacctat ttgtgggaaa aattttcaaa ttataaaatg
    47881 tctgcaaatc tgactgccac ttatcggaaa ttggaggaga tggccaagca agtgaccaat
    47941 ccttcttctc gttattatca agatgaaact gtcgttcgaa cagtcaggga ttccatggaa
    48001 tggatgcata aacatgtcta caatcgtgaa aagagcattg ttgggaactg gtgggattat
    48061 gaaatcggta cacctcgtgc catcaacaat accttgtctc tgatgaaaga atacttctct
    48121 gatgaggaaa ttaaaaaata tacagatgtg attgaaaaat ttgtaccaga tcccgaacat
    48181 ttccgaaaga cgactgataa cccatttaag gctctaggtg gaaacttagt tgatatggga
    48241 agagtaaaag taatagctgg tttactgcgt aaggatgatc aagaaatttc ttctaccatt
    48301 cgctcgattg agcaagtgtt caagttggta gaccaaggtg aaggttttta tcaagatgga
    48361 tcctatatcg accacaccaa tgttgcctat acgggtgctt atgggaatgt tttgattgat
    48421 ggcctgtctc aactgttgcc agtcattcaa aagaccaaga atccaatcga taaagataaa
    48481 atgcaaacca tgtaccactg gattgataaa tcgtttgctc ctttgctggt gaatggagag
    48541 ctgatggata tgagtcgtgg acgctcgatc agtcgtgcaa atagcgaggg gcacgtggcc
    48601 gcagtagaag tactaagagg gattcaccga atagcggata tgtctgaagg agaaaccaaa
    48661 caacgtttgc agagtcttgt gaagaccatt gttcaatcgg atagttatta tgatgtcttt
    48721 aagaatttga agacttataa ggatatcagt ttgatgcaat ccttgttaag tgatgcagga
    48781 gtcgcaagtg ttccaagaac aagttaccta tctgccttta acaagatgga taaaacagcc
    48841 atgtacaatg cagagaaagg gtttggattt ggcttgtcac tcttttccag tcgtaccttg
    48901 aattacgaac acatgaacaa ggaaaataaa cgtggttggt atacgagtga tgggatgttc
    48961 tatctttaca atggcgattt gagtcactat agcgatggct actggccaac agttaatcca
    49021 tataagatgc ctggtacaac agagacggat gctaagagag cggatagcga tacaggtaaa
    49081 gttttaccgt ctgctttcgt tggaacgagc aaactagatg atgccaatgc gacagcaacc
    49141 atggatttca ccaactggaa tcaaacattg actgctcata agagctggtt tatgctaaag
    49201 gataagattg cctttttagg aagcaatatc caaaacactt caacagatac tgctgcaact
    49261 acaatcgacc agagaaaact ggaatcaagt aatccatata aagtctatgt caatgataaa
    49321 gaagcctccc ttacagaaca agaaaaggat tatcctgaaa cccaaagtgt ctttttagaa
    49381 tcgtccgatt cgaaaaagaa tattggttac tttttcttta agaagagttc aatcagcatg
    49441 agtaaggctt tgcaaaaggg agcctggaag gatatcaatg aaggacagtc agacaaggaa
    49501 gttgaaaatg aatttcttac gattagtcag gctcataagc aaaatggaga ttcttatggc
    49561 tatatgctca ttcctaacgt ggatcgtgcc accttcaatc aaatgataaa agagttagaa
    49621 agtagcctca tcgaaaataa cgaaaccctt cagtctgttt atgatgccaa acaaggagtt
    49681 tggggcattg tgaaatatga tgattctgtc tctactattt ccaaccaatt ccaagttttg
    49741 aaacgtggag tctataccat tcgaaaagaa ggggatgaat ataagattgc ctactataat
    49801 cctgaaaccc aggaatcagc tccagatcag gaagtcttta aaaagctaga gcaagcagct
    49861 cagccacaag tacagaattc aaaagaaaag gaaaaatctg aagaggaaaa gaaccattcg
    49921 gatcaaaaga atctccctca gacaggagaa ggtcagtcaa tcttggcaag tctagggttc
    49981 ttgctacttg gggcgtttta tctattccgt agaggaaaga acaactaatt tgttcatcat
    50041 ctagatgaat tacatgaaac tgtggaaaat agaaaaaatc cgaagaaggc caaatatctt
    50101 cggatttttc ttttaaaaaa ggataagttg atacttatcc tttttacttc attatgtgac
    50161 tatagcgttt tgaaactaga ataggacatc ataactgcta aaagatttct ataaattcat
    50221 ttgattttcc taatcaattt gttcgtatcc tatttcactc cactatatta gtccgtctcg
    50281 ctccgtgagg tgcgagacaa aacaaccacc cgctatacgg gtgcgcgtcg aaggttatac
    50341 caaaaaaact ccaaacgcga tacaataaag gtgttcaatc cacttgtaaa gcgaaaggag
    50401 aaaaaatatg gcacaaaagg ctcatagttt atctcacaca aagtggaggt gttctatcac
    50461 attgtgttca cccctaagta tagacgaaaa gtcatctata atcaatatag aagtagttta
    50521 ggcgaaatat ttcatcgctt gtgtagttat aaaggtgttg aaatgatcga gggtcactta
    50581 atgccagacc atgtacacat gttagtcagt attccgtcga ggctaagtgt ttcaagtttt
    50641 atggggtatt taaaaggcaa aagtgcactc atgatgtttg acaaacacgc caatctcaag
    50701 tacaagtttg ggaatcggca tttctgggcg gaaggttatt atgtaagtcc agtagggctt
    50761 aatgaagcca caattaagaa atatagtcaa gattaaagaa attatccagt ggatgatttc
    50821 ttcacgagta tgaaaatttg agaacgagta aagtatgata tatagtaaaa tgaaataaga
    50881 acaggacaaa atcgatcagg acagtcaaat cgatttttaa caatgtttta gaagtatagg
    50941 tgtactattt cagtttcaat ctactatagc actagataaa ttgagtgtaa aagaatatga
    51001 ggatcccttt agggatagtg gtaagtaata ccaaagtctc ttaaagaggc aagtgacgag
    51061 tcaagagcaa taaggcttga acaacgtgaa agccagcgtc tttaggcgct ggctgatgat
    51121 ttgggcttat agctctgaga taaaccaccc gttagacggg tagttatgat tttatctgag
    51181 tgtaatatac tgttgggcaa tctcgctgat gcggtcaaag ttgccttggg aagcgagttt
    51241 attgagttcg ccaccaattc caacggcatc tgcaccagca gcgaaccatt gagggatgtt
    51301 gtttaggccg actcctccgg ttaccattac ggaaacttgt gggatcggtg ccttgactgc
    51361 agagatatat gctggactga gagtactacc tgggaagagt ttgatgattt cactaccggc
    51421 ttcaagtgca gtcgtgatct ctgtgagggt aatacagcct ggaatgtacg gtgtgctgta
    51481 gagattgcac attttcgcag tttcagcatg gaaagatgga gaaacaacgt aatttgctcc
    51541 agctagaatg gcatctctag cagttacggc atcaagcaca gtacctgcac cgatacaaac
    51601 actctgatcg tcctgataca agtctacaag ttccttgatg atttgtcctg catactgatt
    51661 ggtataggcg atttcaatag ctttgatacc gcccttgata caagcaatcg aggcttgtag
    51721 tccttcttcc tttgtatttc ctcgaatgac agcgacaatt ttctgttttt ttagttcaat
    51781 aatcgtatct gatttggtca tgtaattctc ctaacgaatg atatcttgtg catttgccag
    51841 taaattttca atactagttg cggaagtgga gagatggtct cctggaagag tgcatttgag
    51901 agttgcgctc gcaactgcaa agtcaatggt agtttttagg gaggaatgat ggagtagttg
    51961 gtaaagggca ccagatataa aggcatcccc gctaccaatt cgttgataga ctgcagtttt
    52021 tagttggaca gactcttcaa atcgttcttc cagagcatag gcttgataga catttttgtc
    52081 ttgctcatca ctagatcgga gggtatggaa aatagccttg aaaccatagg cttcttttaa
    52141 aagtcgcatg cgattttcca cctcttctag gctagcactg tctcttggga acatctctag
    52201 attttggtca tcaatcatga gaggatcaat accgaagcaa tagtcagtaa aacgtgcaaa
    52261 cttagaaaat tcatacttgg cttctaggac tgaaatcatc tttgttctca gattgagatc
    52321 cattgaaacg acaattcctc ggcgcttggc ttcttccaag agtaggagaa ggatcgcacg
    52381 gacctcttga ccgatagcta tggtgattcc actaaaatga aaatggctaa tcccctgaaa
    52441 gagagaatcc atatctagca tgtttggccg aatctggctg atactcgtat gcttacgatc
    52501 gtagaaaact tcactttgac gacaaccaaa gccgttctcc aaatagtaga ggccgattcg
    52561 atcgccaagc cgacagattg aactggtatc gatttggtgc tgtttcaaga atgtgagaaa
    52621 acgatctcca atctcgttgg cagggagtgc ggtaaagact ttcgttgaga tacccagggc
    52681 ttgcaaatta caagcgatgt taatttctga tccgccaaaa taagtcgaac tggcaacatg
    52741 atcgccgata ctggtggcat ctaatggtga gattcgaatt aatggttcgc caaacagtaa
    52801 tattttcgtc atccattagt tcctttctgg tttagaatag ctttacttgg ctaatatttc
    52861 tttcaaataa gcagcgactt catcatcttg gcagttttca aagaagtatt cttggaagta
    52921 tttgccagag atggtgtctt tgaggaagtc ttggtcgatt gttttaagga tggtcatcaa
    52981 atcattgtgg gtgatttgtt tcacctcgtt taagatacga gcgttgcgtt gttcagggat
    53041 tacacgttct cttgggtagc caccgcccat ttcttcagca aataagcgtt caaacatcaa
    53101 tttgagggtc agttctgccc cccagccaaa tcctttggca taagggatag acaaggcgtt
    53161 accaccattg atttgagaat aaaggtaagc gtcagttggg tccactgcta gaccacagac
    53221 aacaccaggg aagctgttta aagcaagcat agcccctaca cccgtaccac agccggtaac
    53281 aacaaagtca actgcctttg tatttaaaag gatggcagcc attagtccgt tctgcacata
    53341 agttaattga ctttctcctt cttctccacg cataccatag ttaaataatt ggtagccttt
    53401 tttatctgtc gcttctttta gactatcgta aataatgtga ttcttgctag cttgactatt
    53461 ttcattgatt aatgcgattt tcataagatc ttctttctat ttttactcag gttgttttcc
    53521 gatgtaggct aagataccgc catctacata taggatgtgg ccattgacaa aattgctggc
    53581 atcactagcg agaaagacag cagggcccat caaatcttca ggatttcccc aacgtgcagc
    53641 aggtgttttt gcaatgatga actggtcaaa tgggtggcga gaaccatctt cttgcaactc
    53701 acgaagaggt gctgtttgag gagtggcaat ataacccggt ccaattccgt tacattggat
    53761 attggcttca ccgtattcag acgcaatgtt gcgggtcaac attttcaagc cccctttagc
    53821 agcagcataa gcgctaactg tttcacgtcc cagttcgctc atcatcgaac aaatattgat
    53881 aatctttcca tgccctttct ttatcataga aggaataact gcctttgaaa cgataaatgg
    53941 tgcgtttaag tcaatatcga tgaccttacg gaaatcagcg gcgctcattt cgcacattgg
    54001 aactcggcgg ataataccag cgttattaac gaggatgtca atgacaccaa cctcttgttc
    54061 gatttgcttg accatggctt ggataccgtc ctcgtctgtc acgtcacaga catatccatg
    54121 ggcttcgatg ccaacttcac gataagcttc aatcccttta ttgaccagat cttgattgat
    54181 atcgttaaag acaatagtag cgccggcttc agcgtaggat ttggcaatag caaatccaat
    54241 tccataagaa gcgccggtga tgagagcaat ttttcctttt aaagaaaact gctcaattga
    54301 gaatgatgta tttgtcattt gatacttcct ttcaaatttg ttaagacttc tctataacca
    54361 aattatattc tagtaaaccg gttttgtcaa taaataaata tttttattta taaaaagatt
    54421 tattttcctt aaaaatggaa tattttgaaa tttctgtcta ttagaatgat taaaaagata
    54481 atgaaagcgc taatattttt taaaaaaaac tattgacaag ataaaaataa aggattacaa
    54541 tggggaatat aaagtaaacc ggtaaactta aacaagaaag gagaaaagat gaaaattgta
    54601 cttgtagggc atggacattt tgctacaggg atttatagtt ctttacaatt gattgcaggc
    54661 aatcaagaaa atgtggaggc aattgacttt gtggaaggaa tgtcagcaga tgaactcaag
    54721 caaaaaatct tacttgcaat ttcaaatgaa gaagaagttt taatcctaag tgatctcttg
    54781 ggaggatcgc cattcaaggt ttcttctacc ataatgggag aaaatccagc caaaacaatg
    54841 aatgttcttt cgggtttgaa cttagccatg ttaatggaag cagtctttgc tagaatggct
    54901 catagctttg atgaggttgt taataaatca gtagtggcgg cccagggcgg agtcgtaaat
    54961 ggtaaagaat tgttttcaac ggatgcagag gaagaggaag aagatttcga atcgggtatt
    55021 taaagggtaa aagaatgata aaaaaggtta cgattgaaaa aataaaatcg cctgagcgct
    55081 tcttagaagt accacttctg acgaaagaag aagtcggcca ggcaatcgat aaggttattc
    55141 ggcagttaga actcaacctt gactatttca aggaagattt cccgacgcca gctacctttg
    55201 ataatgtcta tccaatcatg gataacacgg aatggaccaa tggtttctgg acaggagaac
    55261 tgtggttggc ttatgaatac agtcaacagg atgcatttaa aaacatcgct cataaaaatg
    55321 ttctttcttt cctggatcgt gtcaataaga gagtagaatt ggatcaccat gatctcggct
    55381 tcttgtacac accgtcttgt atggctgaat ataagataaa tggagatgga gaggctagag
    55441 aagcaacctt gaaagctgca gataagttga ttgaacgcta tcaagaaaaa ggtggtttta
    55501 ttcaagcttg gggagacttg ggcaagaaag agcattaccg tttgattatc gactgcttgc
    55561 tcaatatcca actcttattc tttgcttatc aagaaacagg cgatcaaaaa tactacgata
    55621 ttgcagaaag tcatttctat gcttcagcta ataatgtaat ccgtgatgac gcttcgtcct
    55681 tccacacctt ctattttgat cctgagacag gtcaaccctt taaaggtgta acgagacaag
    55741 ggtatagtga tgattcatgc tgggcacgtg gtcaatcatg gggagtctat ggtattcctt
    55801 tgacttatcg tcacttaaaa gacgagtcct gctttgactt gtttaagggt gtgaccaatt
    55861 atttcttgaa tcgtctgcca aaagatcatg tgtcctattg ggatttgatt tttaatgatg
    55921 gtagtgctca atcacgagat tcttcagcaa cagctatcgc cgtctgtggg attcatgaaa
    55981 tgctaaaaca tctcccagag gtggatgctg acaaagatat ttataaacat gctatgcatg
    56041 ccatgcttcg ttccttgatc gaacattatg caaatgatca atttacccct ggtgggacaa
    56101 gtctcctcca cggtgtgtac tcatggcatt caggtaaagg agtggatgaa ggcaatatct
    56161 ggggtgacta ctattaccta gaagccctta tccgtttcta caaagactgg aacctatatt
    56221 ggtaggagga gaaatatgac aatgccaaat attattatga cccgtatcga tgaacggttg
    56281 attcatgggc aaggacaact ttgggtaaaa tacctaggtt gtaatacggt cattgttgcc
    56341 aatgacgaag taagcacgga caagatgcaa caaactctga tgaaaacagt tgtgccagac
    56401 tcagttgcca tgcgtttctt ccctttgcaa aaggtgattg atatcattca caaggctaat
    56461 cctgctcaaa cgatctttat cgttgtaaag gatgtgaagg atgctttaac cttggtagaa
    56521 ggtggtgtcc ctatcaaaga aatcaatatt gggaacattc acaatgctac tggtaaagag
    56581 caagtgacac gctccatctt cctgggtgaa gaggacaagg cggccctcaa ggaattgagc
    56641 caaactcatc aagtaacatt taatacgaaa acaactccaa caggaaatga tggagctgtt
    56701 caagtcaaca ttatggacta tatttaaaag aggagatcgt tatgtcgatt aatgtatttc
    56761 aagcgatttt aattggatta tggacagctt tctgttttag tggaatgctg ttaggaattt
    56821 acaccaatag atgtattgtt ctgtcatttg gtgtcggaat tattctaggt gatctgccta
    56881 ctgctcttgc aatgggagct attggtgaat tggcttatat gggattcggt gttggtgctg
    56941 gaggtactgt tccaccaaac ccaatcggac ctggtatctt tggtaccttg atggctatca
    57001 ctagtgctgg taaagtcagt ccagaagcgg ctcttgccct ctctactccg attgctgtgg
    57061 cgattcaatt cttacaaact ttcgcctaca ctgtacgtgc tggtgcgcct gaaacagcga
    57121 tgaagcactt gaaaaaccat aatttgaaga aattcaagtt cactctaaat gcaacaattt
    57181 ggttgtttgc ctttattgga tttaccttgg gttgcttggg tgccctttca atggatacct
    57241 tgttgaaact cgtagactac attccaccgg tattgcttac aggtttgaca gttgctggta
    57301 aaatgctccc agctatcggt tttgcgatga tcttgtcagt gatggctaag aaagagttga
    57361 ttccctttgt cttgttggga tatgtttgtg cagcttatct aaacatccca acaattggta
    57421 ttgcaattgt aggtactatc tttgctttga ttgaatttta taacaagcca aaaacagcgg
    57481 atcatgtggt agaggaggaa gcacacgatg actggatcta acaaattaac aaaacgtgat
    57541 tatcttaaaa cgtctttgcg ggcattcttt tgtcaaaatg gatttaacta tagtaactat
    57601 caagggttgg gatatgccaa tgtgatgtat cctgctttga aaaaacacta tggagaggat
    57661 caggaaggtt tctaccaagc cttggaagaa aactgtgaat tctataatac caacccacac
    57721 ttcctgcctt ttattaccag cttgcatctt gtaatgttgg aaaatggccg tccggcaaaa
    57781 gaaacacgta gcatcaagat ggccttgatg ggaccattgg caggtattgg ggattctctt
    57841 tctcaattct gtttagctcc attgttctca accatcgcag cttcgtttgc tcaagaaggc
    57901 ttggttgtcg gtccaatctt gttcttcctt gcgatgaata cgattttaac agcgattaaa
    57961 ttgtcaactg gtctgtatgg atacaaacta ggaacaactg tgattgataa actaagcgaa
    58021 cagatggcaa cgatttctcg tattgccaat attatcggtg taaccgtaat tgctggtttg
    58081 gcagcgacat ctgttaagat tatggtgccg attacctttg ctgcagggga agttaaagca
    58141 gacgctaaac aaagtatcgt aagtattcag ggaatgcttg ataaggttgc tccagctctt
    58201 ctaccagccc tatttacact tttagtttac tacttgatca aagaaaagaa atggacaaca
    58261 tataaactcg ttattttaac agttatcatc ggaattatcg gaagctggct taagattata
    58321 gcttaatgga tacaacattg ttttatggaa tagtgattgt cttggcagtg agtccccttt
    58381 tactgtcaag ctttcattct attcgtcagc aaaagttgct tcgcaaacag atggagcaac
    58441 gacaagagta tttagcttct ttaacatctg gtgatgaagt gttgttattg tctggaattc
    58501 atggaaaaat catttctatc caagatgact tggtctcctt gcagattgca aaaggtgtgg
    58561 tcatctatgt agaaaaggaa agtgtaatgg gaaagacaaa agaactgctt tttaagtagt
    58621 tctttttctg gtaatagata atgaaagaag aaagaagaca attttttgaa agagtcgatg
    58681 gaaaccaatg tcgtgattat atcttgtccc actgttcaaa agactatgag aaagtcaaga
    58741 gttcccttga acgcttgata gacaatcgtt ttatgtttga tagtccttgg gatatggagc
    58801 cttgttcaaa aatccatcaa atccagccga tggtatggga tcaagtattt gaagatgatc
    58861 cagaatggtc ttatatgctc aatcgacaag aatatctctt gcagtttatg atagggtatc
    58921 tggtagaagg agataagggc tatatccaaa agtgcaagtt ctttctattt gattggattg
    58981 agcaggtgag agaattttct cctcaatcct tgatgactag aaccttggat acgggtattc
    59041 gttcctttac ttggttgaaa ctactcttgc tcctcttgaa atttgacttg ctagaggaga
    59101 aagaactaga gaaaattttg gtcagtctag aaaagcagat tgactttatg aaaagccact
    59161 atcgcgccaa gtacaccctt agtaactggg ggattttaca aacaattccg atgcttgcta
    59221 tctattattt cttttcagat aagatggacc tagaagaagc ttaccatttt gcttcagagg
    59281 agttgaaaca gcaaattgag acacagattt taggagatgg aagccagttt gaacagtcga
    59341 ttctctatca tgtagaggtt tataaagcct tgctggattt gtgtctcttg cttccagact
    59401 tgcaagatag ttaccgagag ttgctggaaa agatggcgac ctatattcaa atgatgacag
    59461 gcttagatgg acgaactttg gcttttggtg atagcgattc tacagaaacg acagaaattt
    59521 tgagcctgtc tgctgtggtt ttgaacaagg aagaccttct taacggtctg gatgttaaag
    59581 tcgatttgct tagcctcttg ttcctggggc gagaaaaggt caagcgactg caggaatttg
    59641 aaaggagagc ttggcagcct aagtccatga tctttgaaga ctctggacat gtctgcatta
    59701 aggatgaaca tcgttatcta tttttcaaaa atggtccgct aggaagtgcc catagccata
    59761 gtgacgagaa tagtttttgc ttacagtatc aaggccaacc tattttcata gatgctgggc
    59821 gttattctta tcgggagata tatgaacgtt atctcttaaa gagtgcttgg agtcattcga
    59881 cctgcattgt agatgggaaa gctccggaaa gaatcacggg atcctgggaa tatgaatact
    59941 atcctcactc cctgttttgt caccataaag aaagggaggg agtgcattat attgaggggg
    60001 cttattggtc agcagaacct gatttgcctt atcttcacaa gagaaaaatc ctcatgttgg
    60061 tagaggatgt ctggctcttg gtagatgaca tcaggtgtca aggtcagcat gaggcgttga
    60121 ctcagtttat ccttgacaag gatgtgacct atcaagatgg gaaaatcaat cagttgagac
    60181 tatggagtga agttgatttt gatttggaag ataccatcat ttctcctaaa tacaatgagc
    60241 ttgaaagaag tagcaaactc accaagcgcc aattctttga gaatcagatg ctggattata
    60301 ccatcattgc gcatgagagt tttgaaatta tccgtcattc tgtctaccag acagatgatc
    60361 gtgaagtgga aaatgctctg gcttttgaag tgaaaaatga cgaaacagac aagctgattc
    60421 tgttattaag cgaggatatt ggtgtaggtg aaaaattgtg cctcgttgac ggaacaaaaa
    60481 tgcgtggaaa atgtctagta tatgataaaa taaatgagag aatgattcgc ttgcagtgct
    60541 agaaataggc attttgaata gtgaatatgt tataataagt attagtagga ggtgttttag
    60601 attggagaag aaactgacca taaaagacat tgcggaaatg gctcagacct cgaaaacaac
    60661 cgtgtcattt tacctaaacg ggaaatatga aaaaatgtcc caagagacac gtgaaaagat
    60721 tgaaaaagtt attcatgaaa caaattacaa accgagcatt gttgcgcgta gcttaaactc
    60781 caaacgaaca aaattaatcg gtgttttgat cggtgatatt accaacagtt tctcaaacca
    60841 aattgttaag ggaattgagg atatcgccag ccagaatggc taccaggtaa tgataggaaa
    60901 tagtaattac agccaagaga gtgaggaccg gtatattgaa agcatgcttc tcttgggagt
    60961 agacggcttt attattcagc cgacctctaa tttccgaaaa tattctcgta tcatcgatga
    61021 gaaaaagaag aaaatggtct tttttgatag tcagctctat gaacaccgga ctagctgggt
    61081 taaaaccaat aactatgatg ccgtttatga catgacccag tcctgtatcg aaaaaggtta
    61141 tgaacatttt ctcttgatta cagcggatac gagtcgtttg agtactcgga ttgagcgggc
    61201 aagtggtttt gtggatgctt taacagatgc taatatgcgt cacgccagtc taaccattga
    61261 agataagcat acgaatttgg aacaaattaa ggaattttta caaaaagaaa tcgatcccga
    61321 tgaaaaaact ctggtattta tccctaactg ttgggcccta cctctagtct ttaccgttat
    61381 caaagagttg aattataact tgccacaagt tgggttgatt ggttttgaca atacggagtg
    61441 gacttgcttt tcttctccaa gtgtttcgac gctggttcag ccctcctttg aggaaggaca
    61501 acaggctaca aagattttga ttgatcagat tgaaggccgc aatcaagaag aaaggcaaca
    61561 agtcttggat tgtagtgtga attggaaaga gtcgactttc taaaatgaag gaaaatgact
    61621 tgcaatttct gttaagaaat aaaataatcc cacctagaac aagctaggtg ggattatttg
    61681 cctatgaaat gagaaattat gggagcaagc tcctaaatca actgtttttg atctacttct
    61741 ttaactactt gataaaagtt atagaagtag gccaaacttg aaatgatggt tacgactagg
    61801 aatattgaaa atttccattg gacagggttg gttaaaagtt gtggaaagga tatgaggaga
    61861 aagaagaggg ctgcgttgag gacaggtatc cgttttgatt gtattttctc aagtccttta
    61921 ttgagcgcag gaagaaagag gagtaggagt agtaaaactg tatgagaaac agctcctgaa
    61981 ataagggcga agaaaaggaa aatactgata aaaacatgaa tgatcagtag tctagctagt
    62041 gatttcataa ggcacctcct aatcctggtc ttttttagct cttgcaatac gaagtgagtc
    62101 gacaatatgt atcatcactc cgaaaaagaa agctcccagt atagttttaa aaatatgttt
    62161 tgtatttaga agagaactga taaaatttgg attttcactt gttagggtat caatgagtgg
    62221 aattataaaa aatatcactg ttccataaat cgaacctgct ttcagaccag gataacgtaa
    62281 ctgtttcttt tcttttttca tgagtttgct ccttttttaa aaatcttcct tccaaaagag
    62341 actgttgagg tcagtttgga ggctgcgagc gagattgaga cagagttcca gagttggatt
    62401 gtacttgtcg ttttcaatca tattgatggt ctgtctcgag acaccgatat ccttggcgag
    62461 ctcgagctgg gaaatgccca gttccttgcg aaattctttc acacgattca tctggtctcc
    62521 tttctgattt gtgtcgtata tatttgactt tattatagtc ttttaaacat aaagtgtcaa
    62581 gtatttttga catatttttt gaagaaatag tagtctcctt gtcctatttg tctgacaagt
    62641 gcaagctggt cggatttgtg gtaaaataga taagatatga caaaagaatt tcatcatgta
    62701 acggtcttac tccacgaaac gattgatatg cttgacgtaa aacctgacgg tatctacgtt
    62761 gatgcgactt tgggtggagc aggccatagc gagtatttat taagtaaatt aagtgaaaaa
    62821 ggccatctct atgcctttga ccaggatcag aatgccattg acaatgcgca aaaacgcttg
    62881 gcaccttaca ttgagaaggg aatggtgacc tttatcaagg acaacttccg tcatttacag
    62941 gcacgtttgc gcgaagctgg tgttcaggaa attgatggaa tttgttatga cttgggagtg
    63001 tctagtcctc aattagacca gcgtgagcgt ggtttttctt ataaaaagga tgcgccactg
    63061 gacatgcgga tgaatcagga tgctagtctg acagcctatg aagtggtgaa caattatgac
    63121 tatcatgact tggttcgtat tttcttcaag tatggagagg acaaattctc taaacagatt
    63181 gcgcgtaaga ttgagcaagc gcgtgaagtg aagccgattg agacaacgac tgagttagca
    63241 gagattatca agttggtcaa acctgccaag gaactcaaga agaagggtca tcctgctaag
    63301 cagattttcc aggctattcg aattgaagtc aatgatgaac tgggagcggc agatgagtcc
    63361 atccagcagg ctatggatat gttggctctg gatggtagaa tttcagtgat tacctttcat
    63421 tccttagaag accgcttgac caagcaattg ttcaaggaag cttcaacagt tgaagttcca
    63481 aaaggcttgc ctttcatccc agatgatctc aagcccaaga tggaattggt gtcccgtaag
    63541 ccaatcttgc caagtgcgga agagttagaa gccaataacc gctcgcactc agccaagttg
    63601 cgcgtggtca gaaaaattca caagtaagag ggaaaaagat ggcagaaaaa atggaaaaaa
    63661 caggtcaaat actacagatg caacttaaac ggttttcgcg tgtggaaaaa gctttttact
    63721 tttccattgc tgtaaccact cttattgtag ccattagtat tatttttatg cagaccaagc
    63781 tcttgcaagt gcagaatgat ttgacaaaaa tcaatgcgca gatagaggaa aagaagaccg
    63841 aattggacga tgccaagcaa gaggtcaatg aactattacg tgcagaacgt ttgaaagaaa
    63901 ttgccaattc acacgatttg caattaaaca atgaaaatat tcgaatagcg gagtaagata
    63961 tgaagtggac aaaaagagta atccgttatg cgacgaaaaa tcggaaatcg ccggctgaaa
    64021 acagacgcag agttggaaaa agtctgagtt tattatctgt ctttgttttt gccgtttttt
    64081 tagtcaattt tgcagtcatt attgggacgg gcactcgctt tggaacagat ttagcgaagg
    64141 aagctaagaa ggttcatcaa accacccgta cagttcctgc caaacgtggg actatttatg
    64201 accgaaatgg agtcccgatt gctgaggatg cgacatctta taatgtctat gcggtcattg
    64261 atgagaacta taagtcagca acgggtaaga ttctttacgt agaaaaaaca caatttaaca
    64321 aggttgcaga ggtctttcat aagtatctgg acatggaaga atcctatgta atagagcaac
    64381 tctcgcaacc taatctcaag caagtttcct ttggagcaaa gggaaatggg attacctatg
    64441 ccaatatgat gtctatcaaa aaagaattgg aagctgcaga ggtcaagggg attgatttta
    64501 caaccagtcc caatcgtagt tacccaaacg gacaatttgc ttctagtttt atcggtctag
    64561 ctcagctcca tgaaaatgaa gatggaagca agagcttgct gggaacctct ggaatggaga
    64621 gttccttgaa cagtattctt gcagggacag acggcattat tacctatgaa aaggatcgtc
    64681 tgggtaatat tgtacccgga acagaacaag tttcccaacg aacgatggac ggtaaggatg
    64741 tttatacaac catttccagc cccctccagt cctttatgga aacccagatg gatgcttttc
    64801 aagagaaggt aaaaggaaag tacatgacag cgactttggt cagtgctaaa acaggggaaa
    64861 ttctggcaac gacacaacga ccgacctttg atgcagatac aaaagaaggc attacagagg
    64921 actttgtctg gcgtgatatt ctttatcaaa gtaactatga gccaggttcc actatgaaag
    64981 tgatgatgtt ggctgctgct attgataata ataccttccc aagtggagaa tacttcaata
    65041 gcagtgaatt aaaaatagcg gatgcgacga ttcgagattg ggatgttaat gatggtttga
    65101 cgactggtgg gatgatgact ttcttacaag gtttcgctca ctccagtaat gttggaatga
    65161 gtctacttga acaaaaaatg ggagatgcta cttggttgga ttatctaaac cgctttaaat
    65221 ttggggtccc aactcgcttt ggcttgacag atgaatacgc tggtcaactt ccagctgaca
    65281 atattgtcaa tattgccatg agtgcatttg gtcaggggat ttctgtaacg cagacccaga
    65341 tgctacgtgc ttttacagcc attgccaacg atggggttat gttggaacca aaatttatca
    65401 gtgcccttta tgatccaaat gatcaaactg ctcggaaatc tcaaaaagaa attgtgggaa
    65461 atcctgtttc taaagatgca gctagtctaa ctcggactaa tatgattttg gtagggacgg
    65521 atccggttta tggaaccatg tataaccaca gcacaggcaa gccaactgta actgttcctg
    65581 ggcaaaatgt agccctcaag tctggtacgg ctgaaatagc tgacgagaaa aatggaggct
    65641 acttagttgg ttctactaac aacattttct cggttgtagc catgaaccct gctgaaaatc
    65701 ctgactttat cttgtatgta acggttcaac agcctgaaca ttattcaggt atccagttgg
    65761 gagaatttac aaatcctatc ttggaacgag cttcagctat gaaagactct ctcaatcttc
    65821 aaacaacagc taaagctttg gagcaagtaa gtcaacaaag tccttatcct atgcctagtg
    65881 tcaaggatat ttcacctggt gatttagcag aagaattgcg tcgcaatctt gtacaaccta
    65941 tcgttgtggg aacaggaacg aagattaaaa acagttctgc tgaagaaggg aagaatcttg
    66001 ccccgaatca gcaagtcctg atcttatctg ataaagcaga ggaagtgcca gacatgtatg
    66061 gttggacaaa agcgactgct gagacctttg ctaagtggct caatatagaa cttgaatttg
    66121 aaggttcggg ctctactgtg cagaagcaag atgttcgtgc taacacagct atcaaggaca
    66181 ttaaaaaaat tacattaact ttaggagact aatatgttta tttccatcag tgctggaatt
    66241 gtgacatttt tactaacttt agtaggaatt ccggccttta tccaatttta tagaaaggcg
    66301 caaattacag gccagcagat gcatgaggat gtcaaacagc atcaggcaaa agctgggact
    66361 cctacaatgg gaggtttggt ttttttgatc acttctgttt tggttgcttt ctttttcgcc
    66421 ctatttagta gccaattcag caataatgtg ggaatgattt tgttcatctt ggtcttgtat
    66481 ggcttggtcg gatttttaga tgactttctc aaggtctttc gtaaaatcaa tgaggggctt
    66541 aatcctaagc aaaaattagt tcttcagctt ctaggtggag ttatcttcta tcttttctat
    66601 gagcgtgggg gcgatatgct ttctgtcttt ggttatcaag tgcatctagg gattttctat
    66661 attgtcttcg ctcttttctg gctagtcggt ttttcaaacg cagtaaactt gacagacggt
    66721 gttgacggtt tagctagtat ttccgttgtg attagtttgt ctgcctatgg agttattgcc
    66781 tatgtgcaag gtcagatgga tattctttta gtgattcttg ccatgattgg tggtttgctc
    66841 ggtttcttca tctttaacca taagcctgcc aaggtcttta tgggtgatgt gggaagtttg
    66901 gccctaggtg ggatgctggc agctatctct atggctctcc accaagaatg gactctcttg
    66961 attatcggaa ttgtatatgt ttttgaaaca acttctgtta tgatgcaagt cagttatttc
    67021 aaattgacag gtggtaaacg tattttccgt atgacgcctg tacatcacca ttttgagctt
    67081 gggggattgt ctggtaaagg aaatccttgg agcgagtgga aggttgactt cttcttttgg
    67141 ggagtgggac ttctagcaag tctcctgacc ctagcaattt tgtatttaat gtaagaatgg
    67201 catcctgatg tttcagggtg tttttgtatt taaatacaca atgaaaatca aagaacaaac
    67261 tagaaagcta actttaggct gctcaaaata tagtagattg aaactagaat agtacacatc
    67321 tacttctaaa atattgttag aaatcgattt gactgtcctg atcgatttgt cctgttctta
    67381 tttcatttta atatatagtt ttgagatggt tgatagaact gacgaagtca gctcaaaaca
    67441 tggttttgag gttgtagata aggagaagct gatgtggttt gaagaggttt tcgaagagtg
    67501 taaaaaaata ttggtcagtt aaagccaaaa ctcttgacct tttctgacca atgtagtata
    67561 ttatgaacgt aaggtaaatg aaagccttac tagaacactt atttaaagta aaatagaaag
    67621 aggtgggtct atgtttcatc tagaaatctt cagaagtaaa gatggtctac tcctgcttga
    67681 aaaagaaaaa ccagaaatag tacgtagggt agcggtttaa ctagtctaaa ttttttaaaa
    67741 caatggtcaa agatagtcaa tatcagtaat cataactaag taaacaaaaa gaggtaaaga
    67801 atatgaataa caactttaat aattttaata acatggatga tttatttaac caattgatgg
    67861 gtggtatgcg aggatatagt tctgaaaatc gccgttactt aattaatgga cgcgaagtca
    67921 cacctgagga atttgctcac tatcgtgcga ctggtcaatt accaggaaat gcagaaactg
    67981 atgtgcaaat gccacaacag gcatcaggta tgaaacaaga cggtgtcctt gcaaaactag
    68041 gtcgaaactt gacagcagaa gcgcgtgagg gcaagttgga tcctgttatc ggacgaaaca
    68101 aggaaattca agaaacatct gaaatcctct cacgccgcac caagaacaat cctgttttgg
    68161 tcggagatgc aggtgttggt aagacagcag ttgtcgaagg tctagcgcaa gccattgtga
    68221 acggagatgt tcctgctgct atcaagaaca aggaaattat ttctattgat atctcaggtc
    68281 ttgaggctgg tactcaatac cgtggtagct ttgaagaaaa tgtccaaaac ttagtcaatg
    68341 aagtgaaaga agcagggaat attatcctct tctttgatga aattcaccaa attcttggtg
    68401 ctggtagcac tggtggagac agtggttcta aagggcttgc ggatattctc aagccagctc
    68461 tctctcgtgg agaattgaca gtgattgggg caacaactca agacgaatac cgtaacacca
    68521 tcttgaagaa tgctgctctt gctcgtcgtt tcaacgaagt gaaggtcaat gctccttcag
    68581 cagagaatac ttttaaaatt cttcaaggca ttcgtgacct ctatcaacaa caccacaatg
    68641 tcatcttgcc agacgaagtc ttgaaagcag cggtggatta ttctgttcaa tacattcctc
    68701 aacgtagctt gccagataag gctattgacc ttgtcgatgt aacggctgct cacttggcgg
    68761 ctcaacatcc agtaacagat gtgcatgctg ttgaacgaga aatcgaaacg gaaaaagaca
    68821 agcaagaaaa agcagttgaa gcagaagatt ttgaagcagc tctaaactat aaaacacgca
    68881 ttgcagaatt ggaaaggaaa atcgaaaacc acacagaaga tatgaaagtg actgcaagtg
    68941 tcaacgatgt ggctgaatct gtggaacgaa tgacaggtat cccagtatcg caaatgggag
    69001 cttcagatat cgaacgtttg aaagatatgg ctcatcgctt gcaaaacaag gtgattggtc
    69061 aagataaggc cgtagaagct gtagctcgtg ctatccgtcg taaccgtgct ggttttgatg
    69121 aaggaaatcg cccaatcggc agcttcctct ttgtagggtc tactggggtt ggtaagacgg
    69181 agcttgctaa gcaattggca ctcgatatgt ttggaaccca ggatgcgatt atccgtttgg
    69241 atatgtctga atacagtgac cgcacagctg tttctaagct aattggtaca acagcaggct
    69301 atgtgggtta tgatgacaat agcaatacct taacagaacg tgttcgtcgc aatccatact
    69361 ctatcattct cttggatgaa attgaaaagg ctgaccctca agttattacc cttctcctcc
    69421 aagttctaga tgatggtcgt ttgacagatg gtcaaggaaa tacagtaaac ttcaagaaca
    69481 ctgtcattat tgcgacctca aatgctggat ttggctatga agccaacttg acagaagatg
    69541 cggataaacc agaattgatg gaccgtttga accccttctt ccgtccagaa ctcctcaacc
    69601 gctttaatgc agtcatcgag ttctcacact tgactaagga agatctttct aagattgtag
    69661 atttgatgtt ggctgaagtt aaccaaacct tggctaagaa agacattgac ttggtagtta
    69721 gtcaagcggc taaagattat atcacagaag aaggttacga cgaagtcatg ggggttcgtc
    69781 ctctccgtcg cgtggttgaa caagaaattc gtgataaggt gacagacttc cacttggatc
    69841 atttagatgc taaacatctg gaagcagata tggaagatgg cgttttggtt attcgtgaga
    69901 aagcctaaga tagaattttg aggataaaaa agaaggagcc agctgaaaaa aactggttcc
    69961 ttttgaggta cgacgggcat gtcgtatagt aggttgaaac tagaatagta cacatctact
    70021 tctaaaacat tgttagaaat cgatttgact gtcctgaacg atttgtcctg ttcttatttc
    70081 attttactat atatctgaat atctgaggtg taagtcctcg gtgggcaccc actaccggtg
    70141 aacccaatag cgattcccaa gcctgactat cgtgaggtag tggattaaaa cggtctgggg
    70201 atagaccgtt ttaagtctga cgctggaaat aagaatcgtc agaggaaggg atagcgaaat
    70261 cgtggcttta cgaacaggaa cgtgatagta aggcgtatat agcggataag ggggtctcaa
    70321 actctaaagt tcaaaaaggt agtcgtaacc tatatgcgta aatcacgaga gcaactgaat
    70381 ttgttcattc gaggatggat aaactatttc tcattgggaa atatgaaaag tatagtcgcc
    70441 agcatagatg agcgcttgcg tactcgccta cgagtgatta tctggaagca atggaagaag
    70501 aaatcgagac gattatgggg attgcttaag ttaggagttc ctaaatggat agcagataag
    70561 gtatctggct ggggcgacca ttatcaatta gtagctcaga agtcggtact taaacgtgct
    70621 atatcaaaac cagtcctgga aaaacgtgga ctggtttcgt gtttggatta ttaccttgaa
    70681 cgacatgcgt taaaagttag ttgaaccgcc gtatgccgga cggcacgtac ggtggtgtga
    70741 gaggggctag agattatccc ctactcgatt ttaaatcaca tgacgttcaa aggcatcatc
    70801 tgaaatccct tgttccaaga tgagttttgc ccattcttta gcagagaaga ggctgtggtc
    70861 cttgtagttt ccgcaagatt cgatggttgt ccctgggaca tcttcccaag tagtagtttc
    70921 agcgatttcc ttgagcgaat ccttgataac agctgcgatt ttagcactgg tgtgacgtcc
    70981 ccacataatc atgtggaagc ctgtgcggca accaaatggt gaacagtcaa tcatgccgtc
    71041 aatgcgggta cggatgagtt tggctaagag gtgctcgata gtgtgaaggc cggcagtagg
    71101 gatagagtct tcgtttggtt gcaccaagcg aatatcataa ttggagatga tgtctccttt
    71161 tggtcctgtt tcttccccaa tcaagcgaac atagggtgct ttgacaatgg tgtggtcaag
    71221 ttcaaaactt tcgacaataa cttcttttga catggtaaat cctttcagtt ttcttctctc
    71281 attatatcat aaaggttgct cctgagacag agagaaaacc tctccgaggc tggagaggtt
    71341 gaaatcttta cttacgatat aagcggtcgt attggtagta tgggtcaaag gttacgttga
    71401 tacccagttt acgaaggaca ttcttgtctt catcagtcaa gatgatggtt gagtgggctt
    71461 cgcttccttt gaggttgccg agttcttcca tagcgcgggc agcatcagga ttttctgtag
    71521 ctgtgatagc aagtgcaatc aggatttcat ttgaatgaag gcgtggattg cggctaccga
    71581 gatgatcgat tttaagacct tggattggct taacaacttc cggctcgatt aattttactt
    71641 ctttagcgat atcagctgat tttttgatgg cgttgatcaa ggcagcggct gtagggccaa
    71701 agagttctga gttcttacca gtgacgattt ccccatttgg caattcaaag gctagggctg
    71761 gtccaccagt ttcttctgct ttttggcgcg caacgacagc aaccttacgg tctgcaggtg
    71821 tgataccgag gtcgttcatg agcaactcaa ttttcttgac ggcagcttcg ccaacttttt
    71881 cagctttgaa gtcaagaact gtttgatagt aacggcggat gatttcttgt ttagaagctt
    71941 cgacagcagc ctcgtcatct gtaatagcga aaccaaccat gttgacaccc atatctgtcg
    72001 gtgaagcgta tggtgatttt ccgagaatac gttccaacat gcgcttgagc actgggaaga
    72061 tttcgatatc acggttgtag ttgacagtgg tttctccata ggtttgaaga tggaaggggt
    72121 caatcatgtt gacatcatca aggtcagctg tggcagcttc ataagccaag ttaactggat
    72181 gatgaagggg aagattccaa acagggaagg tttcaaattt agcgtagcca gatttgatgc
    72241 cattgatttg gtcgtggtac atattggaca tacacgttgc caattttcca gaaccgggtc
    72301 caggagcggt tacgacaatc aagttgcgac tggttttgat gtagtcgttt ttgcccatgc
    72361 cttctgggga aatgatgtga tccatatccg tcggatatcc tttgattgga taatgaagat
    72421 aagaatcaat tccgtttttc tcaagttgat tgcggaaggc atctgcagcg ggttggccag
    72481 cgtattgtgt aatgacaacg gaaccaacaa aaatccctaa ttcattgaat ttgtcaatca
    72541 aacgaagaac ttcttggtca taagaaatgc ctaagtcgcc acgtgctttg gaatgttcaa
    72601 tgttgctagc attaatggca atcacaacct caacctgctc tttcaattct tgcaagagct
    72661 tgattttgtt gtcaggttca taaccaggaa ggacacgagc agcgtggaaa tcttctaaca
    72721 ttttaccgcc aaactctaag tagagcttgc cgtcaaattg gttaatgcgc tccaaaatat
    72781 ggtcgcgttg taaattcaaa tattgttcag aactaaaagc ttgttttttc atttttttac
    72841 ctctggactc tattataata aaaaattgga agttaggaaa ctacggagct aaaaaagaaa
    72901 ttaaaaagat taagcaaacg cttgcacaaa attttaaaaa gtgctatcat atactataga
    72961 ttattaaaat aatgaggtaa gaagatgcaa gaaaaatggt ggcataatgc cgtagtctat
    73021 caagtctatc caaagagttt tatggatagt aatggagatg gagttggtga tttgccaggt
    73081 attaccagta agttggacta tctagctaag ctaggaatca cagcgatttg gctttctccc
    73141 gtttatgaca gccctatgga tgataatggc tacgatattg ctgattatca agcgattgca
    73201 acgatttttg gaaccatgga ggatatggat caactgattg cggaagctaa gaagcgtgac
    73261 attcgtatca tcatggactt ggtggttaat catacctcag atgaacatgc ttggtttgtc
    73321 gaagcctgtg aaaatactga cagccctgag cgagactact atatctggcg cgatgaaccc
    73381 aatgacctag attctatctt tagtgggtct gcttgggaat acgatgaaaa gtcaggtcaa
    73441 tactatctcc actttttcag caaaaaacag ccggatctca actgggaaaa tgaaaaactt
    73501 cgccagaaaa tttatgagat gatgaacttc tggattgata aaggtattgg tggtttccgt
    73561 atggatgtta ttgacatgat tggcaaaatt cctgacgaga aggtagtcaa taatggtcct
    73621 atgctccatc cctatctcaa ggaaatgaat caggcgacct ttggagataa ggatctcttg
    73681 acagtagggg agacttgggg agcaacgcca gagattgcca agctctactc tgatccaaag
    73741 gggcaagaat tgtctatggt cttccagttt gaacatatcg gtcttcagta tcaggaaggt
    73801 cagcctaaat ggcactatca aaaagagctg aatatcgcta agttaaaaga aatcttcaac
    73861 aaatggcaga cagagttagg agttgaggac ggctggaatt ccctcttctg gaacaaccat
    73921 gacctccctc gtattgtctc aatctgggga aatgaccaag aataccgcga aaaatctgcc
    73981 aaagcctttg caatcttact tcatctcatg agaggaactc cttatatcta ccaaggtgag
    74041 gagattggga tgaccaacta tccgtttgaa acactagatc aagtagaaga tattgaatct
    74101 ctcaactatg cgcgtgaggc tcttgaaaaa ggtgttccga tgcaagaaat catggacagt
    74161 atccgtgtta ttggacgtga caatgcccgt acccctatgc aatgggacga gagcaaaaac
    74221 gctggtttct caacaggtca accttggttg gcagttaatc caaattacga gatgatcaac
    74281 gtccaagaag cgctggcaaa tccagattct attttctata cctatcagaa actggtccaa
    74341 attcgcaagg agaatagctg gctaattcga gctgactttg aattgcttga tacggctgat
    74401 aaggtctttg cttatatacg taaggatggc gaccgtcgct tcctagttgt ggctaacttg
    74461 tccaatgaag agcaagactt gacagtagaa ggaaaagtca aatctgtctt gattgaaaac
    74521 accctagctc aagaagtctt tgaaaaacaa atcttagttc catgggatgc tttctgtgtg
    74581 gaattactat aaatattttt tgcagaaaaa tttaaaattg aaatcgtata aaaacaaggg
    74641 aggactgtat aaaaggcaga aatcctttgt tttttataac caaggtttat aaaccttcat
    74701 tctcgaaatt caattaactt tacaaattcc cactattaag gagaaagaag acgaacataa
    74761 agaagcgtat ccttagtgca ggcctgactt ttacatctgc tttgctttta gctgcttgcg
    74821 accaatcagg ttcagataca aaaacttact catcaacctt tagtggaaat ccaactacat
    74881 ttaactatct attagactat tacgctgata atatagtcaa ttgaaacaag aacaagacaa
    74941 aagagcctca taaaaggtat tgcaacttgg taataccttt ttgaggtgct ttttgatatg
    75001 agcccatgtt ttctcaatag gattgtactc aggtgagtag ggaggaagag gtaaaagttt
    75061 atgcccaaac tcttcgcata aaagttctag cttccccatt ctatggaatc ttgcattatc
    75121 cataataata accgatggtg tggttaatgt tggtaagaaa aacttctgaa accatacttc
    75181 aaaaaagtcg ctcgtcatca tctcttcgta agtcattgga gcgattaatt caccatttgt
    75241 tagacctgca accaaagaaa tcctctgata tcttcttcca gatactttgc ctcttcttaa
    75301 ctgacctttt aatgagcgac catattctcg ataaaaataa gtatcgaatc ctgtttcatc
    75361 aatctaaaca ggtgctaggt gctttaaact attaaaattc ttaagaaata aggctacttt
    75421 tctgggtctt gttcataatt agattgaaac tagagtagta gacctctgct tctaaaacat
    75481 tgttagaaat cgatttgact gtcctgatcg atttgtcatg ttcttatttc attttactat
    75541 atttttgttt cgcgggaagt ctactaagat acttaaagat gcagatagta aaaaaagatg
    75601 cagatagtaa aaaaatgtag acattaccgt aaaaaagtga tataattata agatgttcaa
    75661 tgtataggtg ttaatcatga gtagacgttt taaaaaatca ggttcacaga aagtgaagcg
    75721 aagtgttaat atagttttgc tgactattta tttattgtta gtttgttttt tattgttctt
    75781 aatctttaag tacaatatcc ttgcttttag atatcttaat ctagtggtaa ctgcgttagt
    75841 cttactagta gccttggtag ggctactctt gattatctat aaaaaagctg aaaaatttac
    75901 tatttttctg ttggtgttct ctatccttgt cagctcagtg tcgctctttg cagtacagca
    75961 gtttgttgga ctgaccaatc gtttaaatgc gacttctaat tactcagaat attcgctcag
    76021 tgtcgctgtt ttagcagata gtgagatcga aaatgttacg caactgacga gtgtgacagc
    76081 accgactggg actgataatg aaaatattca aaaactacta gctgatatca agttaagtca
    76141 gaataccgat ttgacagtcg accagagttc gtcttacttg gttgcttaca agagtttgat
    76201 tgcaggggag actaaggcca ttgtcctaaa tagtgtcttt gaaaatatca tcgagtcaga
    76261 gtatccagac tacgcatcga agataaagaa gatttatacc aagggattta ctaaaaaagt
    76321 agaagctcct aagacgtcta agaatcagtc tttcaatatc tatgttagtg gaattgacac
    76381 ctatggtcct attagttcgg tgtcgcgatc agatgtcaat atcctgatga ctgtcaatcg
    76441 tgataccaag aaaatcctct tgaccacaac gccacgtgat gcctatgtac caatcgcaga
    76501 tggtggaaat aatcaaaaag ataaattaac ccatgcgggc atttatggag ttgattcgtc
    76561 cattcacacc ttagaaaatc tctatggagt ggatatcaat tactatgtgc gattgaactt
    76621 cacttctttc ttgaaaatga ttgacttatt gggaggggta gatgttcata atgatcaaga
    76681 gttttcagct ctacatggga agttccattt cccagtaggg aatgtccacc tagactctga
    76741 gcaggctcta agttttgtac gtgaacgcta ctcactagcc gatggagacc gtgaccgtgg
    76801 tcgcaaccaa caaaaggtga ttgtggctat ccttcaaaaa ttaacgtcaa ccgaagcact
    76861 gaaaaattat agtacgatca ttgatagctt gcaagattct atccaaacaa atatgccact
    76921 tgagaccatg atagatttgg tcaatgctca gttagaaagt ggtggaactt acaaagtgaa
    76981 ttcgcaagac ttgaaaggta caggtcggat ggatcttcct tcttatgcaa tgccagacag
    77041 taacctctat gtgatggaaa tagatgatag tagtttagct gtagttaaag cagctataca
    77101 ggatgtgatg gagggtagat gaaatgatag acatccattc gcatatcgtt tttgatgtag
    77161 atgacggtcc caagtcaaga gaggaaagca aggctctctt ggcagaatcc tacaggcagg
    77221 gggtgcgaac cattgtctct acctctcacc gtcgcaaggg catgtttgaa actccggaag
    77281 agaagatagc agaaaacttt cttcaggttc gggaaatagc taaggaagtg gcgagtgact
    77341 tagtcattgc ttacggggct gaaatttact acacaccaga tgttctggat aagctgggaa
    77401 aaaagcggat tccgaccctc aatgatagtc gttatgcctt gatagagttt agtatgaaca
    77461 ctctttatcg cgatattcat agcgccttga acaagatctt gatgttggga attactccag
    77521 tcattgccca catcgaacgc tatgatgctc ttgaaaataa tgaaaaacgc gttcgggagc
    77581 tgatcgatat gggctgttac acgcaagtaa atagttcaca tgtcctcaaa cccaaacttt
    77641 ttggcgaacg ttataaattc atgaaaaaaa gagttcagta ttttttggaa cgtgatttag
    77701 ttcatgtagt tgcaagtgat atgcacaatt tagacagtag acctccatat atgcaacagg
    77761 catatgatat cattgctaag aaatatggag cgaaaaaagc gaaagaactt tttgtagata
    77821 atcccagaaa aattataatg gatcaattaa tttaggagaa aatatgcaag atcaaaacac
    77881 tttggaaatc gatgtatttc aactattcag agctttatgg aaaagaaagt tggtcatttt
    77941 attagtggca attataactt cttcagttgc ttttgcctac agtacttttg ttatcaaacc
    78001 tgagtttact agtacgaccc ggatttatgt agttaaccgt aatcaggaag agaaatctgg
    78061 tttaaccaat caagacttgc aggcaggttc atacttggtt aaagactatc gtgaaattat
    78121 cctatcgcag gatgttttgg aggaagttgt ttctgatttg aaactagatt tgacgccaaa
    78181 aggtttggct aataaaatta aagtaacagt accagttgat acccgtattg tatctgtttc
    78241 agttaatgat cgagttcctg aagaggcaag ccgtatcgct aactctttga gagaagtagc
    78301 tgctcaaaaa attatcagta ttactcgtgt ttctgatgtg acaacactgg aggaggcaag
    78361 accggcgaca tcaccgtctt cgccaaatat taaacgcaat acactaattg gttttttggc
    78421 aggggggatt ggaactagtg ttatagttct tcttcttgaa cttttggaca ctcatgtgaa
    78481 acgtccggaa gatatcgaag atacactgca gatgacactt ttgggagttg taccaaactt
    78541 gagtaagttg aaataggaga gaggaatgcc gacattagaa atagcacaaa aaaaactgga
    78601 gttcattaag aaggcagaag aatattacaa tgccttgtgt acaaatatac agttgagcgg
    78661 agataaacta aaagtaattt ccgttacttc tgttaaccct ggggaaggaa aaacaactac
    78721 ttccgtaaat atagcaaggt cgtttgcgcg tgcaggctat aaaactcttt tgatcgatgg
    78781 cgatactcga aattcagtta tatcaggagt ttttaaatcg cgtgaaaaaa ttacagggct
    78841 aacagaattt ttatctggga cagctgattt atctcacggt ttatgtgata caaatattga
    78901 aaatttattt gtaattcaat cgggatctgt atcaccaaac cctacggcct tgttacaaag
    78961 taaaaatttt aatgatatga ttgaaacatt gcgtaaatat tttgattata tcattgttga
    79021 tacaccacct attggaattg ttattgatgc ggcaattatc actcaaaagt gtgatgcgtc
    79081 catcttggta acagcaacag gtgaggcgaa taaacgtgat gtccaaaaag tgaaacaaca
    79141 attagaacaa acagggaaac tgttcctggg agttgtttta aataaattgg atatctcggt
    79201 tgataagtat ggagtttacg gttcctatgg aaattatggt aaaaaataac ttagaaaaga
    79261 ttttatggat gaaaaaggat tgaaaatttt tctggcagta ttacagagta ttattgtcat
    79321 tttattggtt tattttctta gctttgttag agagacagaa gttgaacgtt cttcgatggt
    79381 tatactatac cttctccact tttttgtatt ctattttagt tcctatggta acaatttttt
    79441 taaaagaggg cacctagttg agtttaatag tactataaga tatatttttt tctttgcaat
    79501 agctataagt gtattaaact tttttatagc ggaacggttt agtatctcta gaagaggaat
    79561 gatatacttc ttaactttag aaggaatatc cttatacttg ttaaatttct tagtaaaaaa
    79621 atattggaag catgtgtttt ttaatctaaa aaatagcaag aaaattttac tgttaacagt
    79681 aacgaaaaat atggaaaaag ttcttgataa attgctagaa tctgatgaac tttcatggaa
    79741 attggtagca gtaagtgttt tggataaatc tgattttcaa catgataaaa tacctgtaat
    79801 tgaaaaggaa aaaattattg aatttgcaac gcatgaagtt gtggatgagg tgtttgtcaa
    79861 tcttccagga gagagctacg atgttggaga aattatctct aggtttgaga caatggggat
    79921 agatgtaact gtaaatctta aagcatttga taagaatttg ggtcgcaata aacaaattca
    79981 tgagatggtg ggattgaatg tagtcacttt ctctacaaat ttttataaaa ctagtcatgt
    80041 gatttcaaag agaattctcg atatttgtgg tgccactatt ggccttattc tttttgctat
    80101 agctagtcta gttttagttc cattgattcg taaagatggc ggaccagcta tttttgctca
    80161 aactcgtata gggaaaaatg gtcgacattt taccttttat aaattccgtt cgatgcggat
    80221 cgatgctgaa gctatcaaag aacagttgat ggatcaaaat acgatgcaag gtggtatgtt
    80281 taagatagac aatgatcctc gtgttacaaa aattggtcgc tttattcgta aaaccagttt
    80341 ggatgaattg ccgcagtttt ggaatgtctt tataggagat atgagtttgg tgggaacacg
    80401 tccacctaca gtagacgagt atgatcagta tactccagaa cagaaacgtc gactcagctt
    80461 taaacctggt attacaggtt tatggcaggt tagcggccgt agtaaaataa ccgattttga
    80521 tgatgttgta aaattagatg tggcttatat tgataattgg acaatctgga aagatattga
    80581 aattttgctt aaaactgtta aagttgtatt tatgagagat ggagcgaagt aatttctgta
    80641 tatccatcat attaggagag aaatgaaaaa gtcagtttat atcattggtt caaaaggaat
    80701 tcctgctaag tatggaggat ttgaaacttt tgttgaaaaa ttaacagcct tccaacaaga
    80761 taaggctatc caatattatg tggcttgtat gcgtgaaaac tctgcaaaat cagggactac
    80821 tgaggatgtt tttgaacata atggtgctat ctgttataac gtcgatgttc ctaatattgg
    80881 tccagcgcga gccatagtat atgatatcgc ggcaattaac agagctatta aaattgccaa
    80941 agaaaataag gatgaagatc caatcttcta tattctagct tgtcgaatcg gtccgttcat
    81001 ccatggaatt aagaaaaaaa tccaggcgat aggtgggact cttctagtta atccagatgg
    81061 tcacgagtgg ttacgagcta agtggagcgc tccagttcgt cgttattgga aaatttccga
    81121 aggtcttatg gtcaaacatg cagatctttt agtgtgtgat agtaagaata ttgaaaaata
    81181 tatccaagaa gattataaac agtatcaacc taagacaacc tatatcgctt atgggactga
    81241 tacaacacgc tccatattaa agagtagtga cgaaaaagta cgttcttggt tcaaagagaa
    81301 gaatgtttct gagaacgagt attatctagt tgtaggacgt tttgtaccag aaaacaacta
    81361 tgaatctatg attcgtggct ttttggcatc taactctaag aaggactttg tcttaatcac
    81421 aaatgtagaa cagaataaat tttataatca gttgttggca aaaactggtt ttgataagga
    81481 cccacgagta aaatttgtag gtacagtcta tgagcaagag cttcttaaat atattcgtga
    81541 aaacgccttt gcttacttcc acgggcatga agttggtgga accaatcctt cacttttaga
    81601 agctctggca tcaactaaac tgaatttatt gctagatgtt ggctttaacc gagaagttgg
    81661 ggagcaaagt gcgatttatt ggaaaaaaga tgagctttcc caagtaatcg agaaagttga
    81721 acaatttgat gcaaaaatga ttgatgagtt agatagacaa tcaaatcaga gaattgcgga
    81781 ttctttcact tgggaaaaga ttgtcacaga ctacgagaaa gtatttaaag gttagagtta
    81841 atggcagtaa aattaaaata tgataaatca gatattacat ttttagatga tgacgaattg
    81901 aaaaaatacc aatcagaatt gttgaaaatg atatcagatg tgtttacttt ttttgatgaa
    81961 aataggatag cgtattcttt aagtggaggt agcattttag gggcaatccg tcataaaggg
    82021 tttatccctt gggatgatga tgttgatatc aatattccga gggaaagtta cgataaacta
    82081 ttttctctat ttgagttaga caatagtctt agtcgtaaat attatcttca atcagcaaaa
    82141 agtcatccag aattgggact tcatgtttct caaattagaa aaaaaggaac agttgctcgt
    82201 aggaaatacg atcattcggc tgaggagtgc ggtatttcta tagatcttta cattgtagaa
    82261 aatgtataca ataatccagt gaaacgattc tttcaaggtt atacaagtat gtttttgact
    82321 tttgccttgg cttctgtacg agaaacaaag aatcatgccc tgatgaagga aatgtttaga
    82381 ctggaaggta gaaaactaaa ttattcagct ggaaagttaa tggttggttg gttttttgga
    82441 attattccaa ttgaaaagtg gttgaattgg cttgataaat gtaattcaag ctgtaaggat
    82501 tcacatacaa aatatgtatc catacctaca ggaaggaaac actttagacg cgagacttac
    82561 ttgcgagaga atatgaatat ttataaaaag gttccttttg aaactttgat ggtgaatgtt
    82621 cctgtttggt cagaagagta tttagaaatg ttttacggta aagattatat ggtcgttcct
    82681 cctgttgata agagagagca acatttgttt ttagaattga gttacggaga agaatagatg
    82741 aaagtagcga ttttaacagc ttcaggcatt ggaagccgaa ttggtcaaga tatccctaaa
    82801 caatttattc atgttgaaaa taagccagtc attatctata cccttgaaaa atttcaaaat
    82861 catccagaaa ttgatgaaat ctgtattgtt attttaaaag gctgggatca gatggttaaa
    82921 gcttatgcgg aacaatttgg aattacaaag ttaaagatga taacttttgg ggggaagtct
    82981 ggtcaagaat caatttataa cggtcttaga gaagttaaga aagctcatcc caatgatgat
    83041 gtgactgtat taattcatga cgggaatcgt cctttagtga gcaatgatat tattagcaac
    83101 gctttagcaa cataccaaca gtttggaaat gctgttgcag cgataccaac gactgaggta
    83161 gtatttgttt tagaaaaccc acaatcaact tcgtccacag aagcattgaa tcgtgacttg
    83221 ttgagacgaa cacaaactcc tcatgtttac catcttgata atattctatc gcttcatgaa
    83281 aaagcattag aaaatgggat aactgatgtt gcagcatcat gccaactcat gcaactattt
    83341 ggtgaaaaga gttatttctc tcttggaaca gagaaaaact tgaaaattac gactgtagaa
    83401 gatctcgata tttttaaagc cttattgagt tcaactcgag ataagtggat taaatagtaa
    83461 tgacattatt attaaataaa atatatagac aagatgtaga atcttctcta gaaacaatcg
    83521 tcaatattaa tgacttgaat ggcaagtcaa ttttaattac tggagcttct ggtttgattg
    83581 gttcaagtgt cattgaccag ttattattgc taaatgaaat aaggaatttt aacattaaaa
    83641 ttttttgttg tggaagagag tttgaatcat tagaaaaacg atttggtaga caaacagagt
    83701 atttacactt tgtgttctat gatgcgacta aagcacctca ctttgatttt gcagtggact
    83761 acattattca tgctgctagt cctgctagtc ctgaattata cgttaatcag cctgtagaaa
    83821 caatggctag taattttctg ggtatgtata atctactgga atacgccaaa aatgctaaag
    83881 tttcaaatct agtttatatc tcatctagtg aagtttatgg aattagcact agtaataatc
    83941 ctttggacga aaattatatt ggaactgttg atcatcttag cgtacggtct tcttatgcca
    84001 gttcaaaaag agctactgaa acactttgtg ttagttttgc ttccgagtat ggaatcaaaa
    84061 taatgatagt aaggccagga catatctatg gtcctagtgc caaggactct gataatcgtg
    84121 tatcatcatt ttttatgaca gaagcgattg ctgggcgtga tattgtcata aaaagtacag
    84181 gtagtcagtt aagatcctat tgttatagtt tggattgtgc cagtgcaatt ctaagtgttc
    84241 ttctttcggg tggatcagga caagcttata atgtttccaa tccaaattca attattacta
    84301 taaaacagat ggcaacttgc attgcagatg cttcaggagt cagagttctt tatgatatac
    84361 ctataactca agagcgaaag cgggaaaatc ctatggtaaa tgcaagctta gatagtgaga
    84421 aaattgagtc cttgggatgg tcaggtctat tttcagctga agtaggcttc catcacacat
    84481 ttagtatttt aaaggagtta tcaagtgaaa aatgatagta ttttaatcat gatgacaaca
    84541 tacaatggag aagaatttat acgtgaacag ttggagagta tcctttttca aaccattaca
    84601 gcatggaaac tatagattcg tgatgacaat tctagtgatc aaataagagc aattattaaa
    84661 gaatacgaag aaaaagatag tcaatttttg atataagcta tccaagagga ttttggagaa
    84721 gtttttttat tgaagagtgg ccttaagaag gtcttctagg cttaatttag gtttttgtcc
    84781 accttttgcg tgtttaagtt gataagctgt ttttaataca gctaacatct cttcaaaaat
    84841 ggtacgctga acgtcaacaa gacgcttaaa tcgtacatca gttagttgtt tacttgcttc
    84901 ataattcata gaactattat accatatttt atttcgcagg aaatctattg aaaaaacgac
    84961 actatattat caatggggat gttaggacta tatgttaaaa acatgcgaga gtatcttttg
    85021 ttatgaatat tatgagagta catagaaaga tagagattcc actgatggaa ttttatagag
    85081 aagggaaaac tgtatttatt tggatatatt gaactccgtg gaatggattg attagggtat
    85141 gtacatatgg taaatggatg taacccgcaa acagaacacg gatggagtac acatttgcta
    85201 attacagaga ttcattgaaa aatattagag tttcaaatag gaaaagtaat gattgacgga
    85261 gattttatga atagaagact tgtaataaaa aagaaaagta taatgttttt catgcttatg
    85321 ttatgtgtta cggcatttta tgggacaaat tattggtata caaatatata tatatatgat
    85381 tttatgatta taacatcatg cttattatca ataatagtat ttgtatgtaa tggtattaga
    85441 attgataaaa catattataa agggacaata atactgggta ttgtaatgtg gttttcagga
    85501 cttattgctg cacaaggaaa agggctccct gctattgtaa tctttaaaga gagtttatat
    85561 actattactc caataatgat atttttagct ttccgaccta tgataaagtc aataaaagac
    85621 acttcattat tccttcgtac tatttctgct gccggtgtta tatgtaattt aattgcttgt
    85681 attgaaatgt tctttgccaa aagaggattt gattttctaa atataagtgt atttgaaaaa
    85741 cttagaaatg gtactcctag atttacaatt ggagaaacaa taatagttct tagttttttt
    85801 atctcctgta gtgttgtttt tagtaaaggg ggaaagagaa atagacgcat tttccatgtt
    85861 ctaaatatag ctctcacagc tataaattta gtgtatatta ttaaaacaag gacactgaat
    85921 ttatatattt tatcaacact tatgatggtg cctgttttaa aaaaaaatgt aaagaaacaa
    85981 cttaagtttt ggattgtgtt tttgatatct ataattctta cttttgtttc tgcagaatat
    86041 tttattccaa tagtcaaaaa tttaattcat agtgatcatg ggattc
//
LOCUS       DAVMJI010000004        84316 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.004, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000004 DAVMJI010000000
VERSION     DAVMJI010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.004"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            232..643
                     /locus_tag="VYR58_000275"
                     /pseudo
     CDS             232..643
                     /locus_tag="VYR58_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            646..1577
                     /locus_tag="VYR58_000276"
                     /pseudo
     CDS             646..1577
                     /locus_tag="VYR58_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            1552..2130
                     /locus_tag="VYR58_000277"
     CDS             1552..2130
                     /locus_tag="VYR58_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV3621505.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKA
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESMV
                     RDNSTAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(2187..2471)
                     /locus_tag="VYR58_000278"
     CDS             complement(2187..2471)
                     /locus_tag="VYR58_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV3621506.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(2525..3460)
                     /locus_tag="VYR58_000279"
     CDS             complement(2525..3460)
                     /locus_tag="VYR58_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV3621507.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3564..4007
                     /locus_tag="VYR58_000280"
     CDS             3564..4007
                     /locus_tag="VYR58_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV3621508.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            4123..4389
                     /locus_tag="VYR58_000281"
     CDS             4123..4389
                     /locus_tag="VYR58_000281"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV3621509.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            4386..4760
                     /gene="crcB"
                     /locus_tag="VYR58_000282"
     CDS             4386..4760
                     /gene="crcB"
                     /locus_tag="VYR58_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV3621510.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            4754..5083
                     /gene="crcB"
                     /locus_tag="VYR58_000283"
     CDS             4754..5083
                     /gene="crcB"
                     /locus_tag="VYR58_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV3621511.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            5202..5549
                     /gene="rplS"
                     /locus_tag="VYR58_000284"
     CDS             5202..5549
                     /gene="rplS"
                     /locus_tag="VYR58_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV3621512.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            5591..5662
                     /locus_tag="VYR58_000285"
     tRNA            5591..5662
                     /locus_tag="VYR58_000285"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5624..5626,aa:Arg,seq:cct)
     gene            complement(5717..6523)
                     /gene="yidA"
                     /locus_tag="VYR58_000286"
     CDS             complement(5717..6523)
                     /gene="yidA"
                     /locus_tag="VYR58_000286"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV3621513.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMVGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(6536..7840)
                     /locus_tag="VYR58_000287"
     CDS             complement(6536..7840)
                     /locus_tag="VYR58_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV3621514.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            7912..8289
                     /locus_tag="VYR58_000288"
     CDS             7912..8289
                     /locus_tag="VYR58_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV3621515.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDRQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            8379..8711
                     /locus_tag="VYR58_000289"
     CDS             8379..8711
                     /locus_tag="VYR58_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV3621516.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            8723..10294
                     /gene="ffh"
                     /locus_tag="VYR58_000290"
     CDS             8723..10294
                     /gene="ffh"
                     /locus_tag="VYR58_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV3621517.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(10489..11772)
                     /locus_tag="VYR58_000291"
     CDS             complement(10489..11772)
                     /locus_tag="VYR58_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV3621518.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(12026..12739)
                     /gene="rsmG"
                     /locus_tag="VYR58_000292"
     CDS             complement(12026..12739)
                     /gene="rsmG"
                     /locus_tag="VYR58_000292"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV3621519.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12833..13393
                     /locus_tag="VYR58_000293"
     CDS             12833..13393
                     /locus_tag="VYR58_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV3621520.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            13395..14294
                     /gene="htpX"
                     /locus_tag="VYR58_000294"
     CDS             13395..14294
                     /gene="htpX"
                     /locus_tag="VYR58_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV3621521.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(14443..16002)
                     /locus_tag="VYR58_000295"
     CDS             complement(14443..16002)
                     /locus_tag="VYR58_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV3621522.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQSVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(16241..16557)
                     /locus_tag="VYR58_000296"
                     /pseudo
     CDS             complement(16241..16557)
                     /locus_tag="VYR58_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
     gene            16726..17268
                     /locus_tag="VYR58_000297"
     CDS             16726..17268
                     /locus_tag="VYR58_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV3621523.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            17268..17897
                     /gene="nth"
                     /locus_tag="VYR58_000298"
     CDS             17268..17897
                     /gene="nth"
                     /locus_tag="VYR58_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV3621524.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            18108..18629
                     /gene="pyrR"
                     /locus_tag="VYR58_000299"
     CDS             18108..18629
                     /gene="pyrR"
                     /locus_tag="VYR58_000299"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV3621525.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            18648..19571
                     /locus_tag="VYR58_000300"
     CDS             18648..19571
                     /locus_tag="VYR58_000300"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV3621526.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            19621..20700
                     /gene="carA"
                     /locus_tag="VYR58_000301"
     CDS             19621..20700
                     /gene="carA"
                     /locus_tag="VYR58_000301"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV3621527.1"
                     /translation="MTKRILVLEDGTVFEGKAFGSDIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEIFKQSN"
     gene            21012..24188
                     /gene="carB"
                     /locus_tag="VYR58_000302"
     CDS             21012..24188
                     /gene="carB"
                     /locus_tag="VYR58_000302"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV3621528.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(24463..25272)
                     /locus_tag="VYR58_000303"
     CDS             complement(24463..25272)
                     /locus_tag="VYR58_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV3621529.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(25274..26077)
                     /locus_tag="VYR58_000304"
     CDS             complement(25274..26077)
                     /locus_tag="VYR58_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV3621530.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYELLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKI
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(26087..27574)
                     /gene="tacF"
                     /locus_tag="VYR58_000305"
     CDS             complement(26087..27574)
                     /gene="tacF"
                     /locus_tag="VYR58_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV3621531.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIIKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNRIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIILLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            27910..28617
                     /locus_tag="VYR58_000306"
     CDS             27910..28617
                     /locus_tag="VYR58_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV3621532.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            28622..29644
                     /locus_tag="VYR58_000307"
     CDS             28622..29644
                     /locus_tag="VYR58_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV3621533.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            29661..30530
                     /gene="licA"
                     /locus_tag="VYR58_000308"
     CDS             29661..30530
                     /gene="licA"
                     /locus_tag="VYR58_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV3621534.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            30520..31398
                     /locus_tag="VYR58_000309"
     CDS             30520..31398
                     /locus_tag="VYR58_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV3621535.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            31410..32099
                     /locus_tag="VYR58_000310"
     CDS             31410..32099
                     /locus_tag="VYR58_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV3621536.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            32195..33043
                     /gene="dprA"
                     /locus_tag="VYR58_000311"
     CDS             32195..33043
                     /gene="dprA"
                     /locus_tag="VYR58_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV3621537.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            33927..34970
                     /locus_tag="VYR58_000312"
     CDS             33927..34970
                     /locus_tag="VYR58_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV3621538.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            35137..37224
                     /gene="topA"
                     /locus_tag="VYR58_000313"
     CDS             35137..37224
                     /gene="topA"
                     /locus_tag="VYR58_000313"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV3621539.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            37330..37689
                     /locus_tag="VYR58_000314"
     CDS             37330..37689
                     /locus_tag="VYR58_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV3621540.1"
                     /translation="MRLIYLIIGFLSLGLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            37782..38414
                     /locus_tag="VYR58_000315"
     CDS             37782..38414
                     /locus_tag="VYR58_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV3621541.1"
                     /translation="MIYEFCAENMTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            38458..39114
                     /locus_tag="VYR58_000316"
     CDS             38458..39114
                     /locus_tag="VYR58_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV3621542.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            39133..39765
                     /locus_tag="VYR58_000317"
                     /pseudo
     CDS             39133..39765
                     /locus_tag="VYR58_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
     gene            39793..40227
                     /locus_tag="VYR58_000318"
     CDS             39793..40227
                     /locus_tag="VYR58_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEV3621543.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGCSVSYHDMPSV"
     gene            40239..41276
                     /gene="leuB"
                     /locus_tag="VYR58_000319"
     CDS             40239..41276
                     /gene="leuB"
                     /locus_tag="VYR58_000319"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV3621544.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVSMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            41273..41542
                     /locus_tag="VYR58_000320"
     CDS             41273..41542
                     /locus_tag="VYR58_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV3621545.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            41546..41905
                     /gene="leuD"
                     /locus_tag="VYR58_000321"
     CDS             41546..41905
                     /gene="leuD"
                     /locus_tag="VYR58_000321"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV3621546.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            42067..42690
                     /locus_tag="VYR58_000322"
                     /pseudo
     CDS             42067..42690
                     /locus_tag="VYR58_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42856..44787
                     /locus_tag="VYR58_000323"
     CDS             42856..44787
                     /locus_tag="VYR58_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV3621547.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQTVADDNEGDENDDADY"
     gene            44774..46090
                     /locus_tag="VYR58_000324"
     CDS             44774..46090
                     /locus_tag="VYR58_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV3621548.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            46265..47251
                     /locus_tag="VYR58_000325"
     CDS             46265..47251
                     /locus_tag="VYR58_000325"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV3621549.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            47315..47386
                     /locus_tag="VYR58_000326"
     tRNA            47315..47386
                     /locus_tag="VYR58_000326"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47348..47350,aa:Arg,seq:ccg)
     gene            47569..48267
                     /locus_tag="VYR58_000327"
     CDS             47569..48267
                     /locus_tag="VYR58_000327"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV3621550.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            48258..51797
                     /gene="smc"
                     /locus_tag="VYR58_000328"
     CDS             48258..51797
                     /gene="smc"
                     /locus_tag="VYR58_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV3621551.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALDIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEVALKTLQDEMARLTESLEAIKSQGEQARIQEQGLFLAYQQTSQQV
                     EELETLWKLQEEEKDRLSEGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVTDIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            51794..52588
                     /locus_tag="VYR58_000329"
     CDS             51794..52588
                     /locus_tag="VYR58_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV3621552.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLGKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            52588..53406
                     /locus_tag="VYR58_000330"
     CDS             52588..53406
                     /locus_tag="VYR58_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV3621553.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGINQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAVANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            53410..54699
                     /gene="ftsY"
                     /locus_tag="VYR58_000331"
     CDS             53410..54699
                     /gene="ftsY"
                     /locus_tag="VYR58_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV3621554.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVDEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDSEPVVGVSQEEVEEFPHSEELPEEEKLDHE
                     GTIEENNSEVLEAERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVLEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(54745..56232)
                     /locus_tag="VYR58_000332"
     CDS             complement(54745..56232)
                     /locus_tag="VYR58_000332"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV3621555.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTAATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(56381..57121)
                     /locus_tag="VYR58_000333"
     CDS             complement(56381..57121)
                     /locus_tag="VYR58_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV3621556.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(57121..59286)
                     /locus_tag="VYR58_000334"
     CDS             complement(57121..59286)
                     /locus_tag="VYR58_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV3621557.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            59456..60409
                     /locus_tag="VYR58_000335"
     CDS             59456..60409
                     /locus_tag="VYR58_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3621558.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            60486..62474
                     /gene="uvrB"
                     /locus_tag="VYR58_000336"
     CDS             60486..62474
                     /gene="uvrB"
                     /locus_tag="VYR58_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV3621559.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVQALD"
     gene            62484..63047
                     /locus_tag="VYR58_000337"
     CDS             62484..63047
                     /locus_tag="VYR58_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3621560.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            63013..63501
                     /locus_tag="VYR58_000338"
     CDS             63013..63501
                     /locus_tag="VYR58_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3621561.1"
                     /translation="MTVIIKSMETPEEIEDKSLVHWQTWREAYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            63575..64042
                     /locus_tag="VYR58_000339"
     CDS             63575..64042
                     /locus_tag="VYR58_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV3621562.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVIYYKATEFSGSLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(64039..64554)
                     /locus_tag="VYR58_000340"
     CDS             complement(64039..64554)
                     /locus_tag="VYR58_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV3621563.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(64566..65093)
                     /locus_tag="VYR58_000341"
     CDS             complement(64566..65093)
                     /locus_tag="VYR58_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV3621564.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPIVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(65376..65939)
                     /locus_tag="VYR58_000342"
     CDS             complement(65376..65939)
                     /locus_tag="VYR58_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV3621565.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(65923..66474)
                     /gene="coaC"
                     /locus_tag="VYR58_000343"
     CDS             complement(65923..66474)
                     /gene="coaC"
                     /locus_tag="VYR58_000343"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV3621566.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(66486..67175)
                     /gene="coaB"
                     /locus_tag="VYR58_000344"
     CDS             complement(66486..67175)
                     /gene="coaB"
                     /locus_tag="VYR58_000344"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV3621567.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            67405..69075
                     /locus_tag="VYR58_000345"
     CDS             67405..69075
                     /locus_tag="VYR58_000345"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV3621568.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            69403..70578
                     /gene="mutY"
                     /locus_tag="VYR58_000346"
     CDS             69403..70578
                     /gene="mutY"
                     /locus_tag="VYR58_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV3621569.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            70633..71337
                     /locus_tag="VYR58_000347"
     CDS             70633..71337
                     /locus_tag="VYR58_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3621570.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            71330..72679
                     /gene="vicK"
                     /locus_tag="VYR58_000348"
     CDS             71330..72679
                     /gene="vicK"
                     /locus_tag="VYR58_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV3621571.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            72681..73490
                     /locus_tag="VYR58_000349"
     CDS             72681..73490
                     /locus_tag="VYR58_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV3621572.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            73581..73823
                     /locus_tag="VYR58_000350"
     CDS             73581..73823
                     /locus_tag="VYR58_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV3621573.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMIHDLGLKDE"
     gene            73825..74079
                     /locus_tag="VYR58_000351"
     CDS             73825..74079
                     /locus_tag="VYR58_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV3621574.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            74154..76025
                     /locus_tag="VYR58_000352"
     CDS             74154..76025
                     /locus_tag="VYR58_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEV3621575.1"
                     /translation="MTIDISEESLAKESADLLKILLKDRTTKKSIVWATHSYELLGKG
                     FAPSDRINPSKVTGNFANLIQPRSEKSKYEQKDRTKIRAEVFTPTWLVAKQNGYVESK
                     LGSLSLEEYVDLRWLEVTCGEAPYMVTRYDTVTGEEIPLSERVGFVDRKLQRISREVS
                     DEVTFYKLVKDAYHASYGYEYQGDSLLLARENLLATFEDYYLAKTGNQPTLEQKKEIA
                     TIISYNVFQMDGLKKSSPYSAKQKQSQQLSLFADELEVQEVEESKTHIKDWKKNRMIG
                     FERLSSEESEMKFDVVIGNPPYQETGEARDEPIYHYFIDEAYKIADKSILITPARFLF
                     KAGQTPKNWMEKMLEDKHLKVQFYELKSGKVFTGTDIKGGVAITYRDVDKDLGPIGVF
                     TIFETLNGIVKKIEKHPEFETFSDLVYPQGIYRFSNKLFSDYPNAEKLQGKGTKNKIV
                     SKSLTQLDFVFKNNEEKDHVALLGRIGSERVYRYINKKYLDLPETFENYNVFVPEANG
                     SGALGEVLSTPLIGEPLIGHTDTFLSIGNFKTKFEADACIKFIKTKFARVLLGVLKVT
                     QHNSRKTWYYVPLQDFTVNSDIDWTQSVTDIDRQLDQKYDLSPEEIAFIENHVREMD"
     gene            76190..79444
                     /locus_tag="VYR58_000353"
     CDS             76190..79444
                     /locus_tag="VYR58_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001143847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV3621576.1"
                     /translation="MPVEIKTTKEIHPKIYAYTTPTVTSNEGWIKIGYTERDVTQRIK
                     EQTHTAHIATDVLWTGDAAYTEEPDKGKTFKDHDFHHFLSFHDVERRPKTEWFYFNGT
                     PEKSKNLFDKFVQHDLSGYQPGKGQDYTLRQEQEEAVAKTLAYFQEHAGGKFLWNAKP
                     RFGKTLSTYDLARRMEAVNVLIVTNRPAIANSWYDDFETFIAGQTTYKFVSESDSLKS
                     RPILSRQEFLGILADDVRQLAFISLQDLKGSVYLGGEHDKLKWVTDLHWDLLVIDEAH
                     EGVDTFKTDQAFNKIRRNFTLHLSGTSFKALAKGDFTEEQIYNWSYADEQAAKYSWSL
                     EQEEENPYESLPQLNLFTYQMSQMIGEKLEKGAQIDGENIDYVFDLSEFFATDDKGKF
                     IHEHDVRNWLDTLSSNEKYPFSTKELRNELKHTFWLLERVASAKALKALLEEHPIYEN
                     YEIVLAAGDGRMSEEDDKVKLKSLDLVRKAIAENDKTITLSVGQLTTGVTIPEWTGVL
                     MLSNLKSPALYMQAAFRAQNPYSWSDNKGNHFRKERAYVFDFAPERTLILFDEFANNL
                     SLVTAAGRGTSATREENIRELLNFFPIIAEDRAGKMVEIDAKAVLTTPRQIKAREVLK
                     RGFMSNLLFDNISGIFQASQTVLDILNELPVEKEGKVQDSSDLLDFSDVTVDDEGNAV
                     VDHEIVVNQQMRLFGEKVYGLGESVAELVTKDEERTQKQLVNDLSKTVSSVIVEELKA
                     DYSLKTRETEQIKKQITATLENEIRKNDIERKISEAHIKQELQQQLKEANDKAQKDKI
                     QEDLEKRLEENKLIHKEKLEQTLKKEVEKMPEKFIEQVEIKRVEQLKQSAQDEIRDHL
                     RGFARTIPSFIMAYGDQTLTLDNFDAFVPEHVFYEVTGITIDQFRYLRDGGQDFAGHL
                     FDKATFDEAIQEFLRKKKELADYFKDQKEDIFDYIPPQKTNQIFTPKRVVKRMVDDLE
                     KENPGIFDDPSKTFIDLYMKSGLYIAELVKRLYNSNGLKEAFPNPEERLKHILEKQVY
                     GFAPSEIIYNISTNFIFGNLSKDISRKNFVLADTIPAAKEGSIQKLVDSYFENN"
     gene            complement(79830..80816)
                     /locus_tag="VYR58_000354"
     CDS             complement(79830..80816)
                     /locus_tag="VYR58_000354"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV3621577.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            81010..83478
                     /gene="gyrA"
                     /locus_tag="VYR58_000355"
     CDS             81010..83478
                     /gene="gyrA"
                     /locus_tag="VYR58_000355"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV3621578.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            83478..84221
                     /gene="srtA"
                     /locus_tag="VYR58_000356"
     CDS             83478..84221
                     /gene="srtA"
                     /locus_tag="VYR58_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV3621579.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT        25854 a        15073 c        18498 g        24891 t
ORIGIN      
        1 taaaatgaaa caagaacagg acaaatcgat ttctaacaat gttttagaag tagaggtgta
       61 ctattctagt ttcaatctat tatatttcgt ctgatgggca aattttataa agagattata
      121 gaacttttat agtggtttga aataagatgt gaacaactct atcaggaaag tcaaattaat
      181 ttatagaaat attttagcag ccaaggtgta ctgttataga ttcaatacac tatagactgt
      241 aatcaaacaa cgatttgacg aaatgtaaaa aaatatgagg agttcggact cgactctctc
      301 cttcaagaaa cacgtggtgg tcgtaaccat gcatatatga cagttgagga agagaaagcc
      361 tttcttgccc gtcatttgaa ggctgcagag gcaggagaat ttgttacaat tgatgcctta
      421 tttcaggctt ataaaaagga gttaggtcgt tcctacacac gtgatgcctt ctatcaactg
      481 ttgaagcgcc atggctggcg aaatattacg ccacgtccag aacatcttag gaaagcagac
      541 gctcaaacca ttgtcgcgtc taaaaataaa atctcaattc aagaagacaa gaaagcgctt
      601 taaaatcagt agaccttttc ataaggttcg cttgatgtac caaatagtac gcccatgcaa
      661 aagaatatct attttgttgt cttggacctg catacgacgg atagagataa aattatccag
      721 ctattcaagg attggacgga tgacagttgg gctcaatcct catcgtttga cgctgacttt
      781 tggtgtatct gcaagtttct tgaaaaggat gaacttggaa aacaagcgcc ctcgactgtt
      841 cagggattta cctctatttc ctaaggagca attacgtgaa aaatatactg gtggagatat
      901 tgtgattcat gcttgtgcag atgatgagca aattgccttt cacgttattc gcaatctcat
      961 acgtaagggt agaaatgcgg tgccccttcg ttggagtcag tctggatttg cagctatcgg
     1021 ggacgaatgg agactccgtg gaacctcttt ggttttaagg atggaacagc aaatccaacc
     1081 aaggagcaag actttgaccg cgttatctgg gctgatagta aggactggat ggaaaatggt
     1141 tcttatatgg cagttcgtcg gattcagatg tttttagaga cctgggaccg cactggtctc
     1201 gaagaacaag aaaatacctt tggtcgttac aaggaaagta gtgccccttt cggtaaaaaa
     1261 atgagtttga tgaagtgaat ttgagttttt tgctagatga ttcgcatgtt cgtttggcta
     1321 agtaagtgga caagccactt ttgcgttgtt cttactctta ctcagatggc attgatgaaa
     1381 agactggtca gtttgatacg ggattgctct tcatttcttt ccagaaggat cctgataact
     1441 ttgttaaggt tcaaactaac ctaggtgcta ctgataagat gaatgaatac atcactcaca
     1501 taggtagtgg actttttact tgctttggtg atgtggagaa aggaggctac attggtcaga
     1561 aattattgga aggctaaaag ctggttacta gttttagctt tgtcattttt aattctttcc
     1621 ccagcaggtg cccaagaaag cttgagtttt ttctttgtga aaatcacaga tgcatccaaa
     1681 gcggttaaaa atggtggtca gactgagacc cagaaactcg ttacgaagat ggcatcagac
     1741 ttcgaaagag tagaaaataa ggattctgag gttggtaaga ttgttaagga aaagttagct
     1801 ctatctggag atattactga agccaaactc accgaaattt cctcagctct attagctttt
     1861 gaaaaagaac aaaatcctgt tgacctagat gcggaaaagg aaaaattggt aaaccgtcta
     1921 agtcctcgtt ttgaaacctt agagcaggcc attgcctcca aagatttgga aaaggttcga
     1981 gaggccttta agaaaatgaa ttccacttgg accatcaatg aaagtatggt tcgtgacaat
     2041 agtacagctc attatggacg tgttgaaaca gctatttcct tcctgcctag tagcatggaa
     2101 atcgaaccta cagatgagtc tggaacatga aaacagcagt tgatttcaag aaacaaaaaa
     2161 gaacagccga aactgttctc ttatcattat ttgagaccgt attttttgtt gaaacgatcc
     2221 acgcgtccat ctgcttgagt gaacttttga cgtccagtgt agaatgggtg tgagtctgat
     2281 gaaatttcca cacggatcaa tgggtaagtt tcgccttcga actcaactgt ttcgttagag
     2341 cgttttgttg aaccgctaag gaattggtaa ccagtagttg tgtccatgaa gacaactggg
     2401 cgatattctg gatggatatc ttttttcatt ttgcaatatt tcctttctgc catggtctct
     2461 ttgcgagcca tagattgtta ccatactagt ctatcagatt ctgaaaagtt tggcaagtat
     2521 tttatcagtt tttaagcaag ttttttaact tttggtagat gatttcattt tcttctaggc
     2581 tataggaatt agcaccactt gctagagggt ggcctccacc atcatgctcc ttggcgattt
     2641 cattgatagg atggatttta ctgcgtaagc gaactcggta gtggccatca gcctgttcga
     2701 caaaaattcc ccagagactc actctgtcaa tgcgtccagg tgcaccgaca atggctgcag
     2761 tttcagcatc ggttacattg tattgtttca agacttcttg actcaggata acgcgagcag
     2821 caccattttc atccacttcc agatggtcgt agatgtagcc ttgcagttta gcaattttgt
     2881 agctcatagt gtccattttg cgagtgagag ccgcaaagtc aaagttatgt tctctcaaat
     2941 aagcagccag gcgaagagtc cgtgcagtgg tagaagggta gaggaagcga cctgtatcac
     3001 cgacaattcc tgcaaagagc aactcagcat cgcgatctgc caaggctagt tgggttgttt
     3061 gggcaaatag ggtaatcatc tcgctagcgc tacttgaact agtatcgacc caagacaggt
     3121 caccgtatac atcatcattt ggatggtggt caatcttaat gagaaaatca ccttgactat
     3181 agcgcttatc atcgatacga gcagtattag ctgtatcaca gacgatgaca agtgcgcctt
     3241 ggtaggctct atcttcaaca agatccatct cagccatcca agtaagagtt ggttcatcaa
     3301 aaccgacggc tttgatggtt ttttctggga aatgatgttc cagcaaggct ttcaatccca
     3361 cctgacttcc caaggcatca gggtctggtt tcatatgacg atgaatgata atggtgtcgt
     3421 attctttaat tttttctaaa atttgttggc aaatctccat aaataacctc aattctttct
     3481 catttcattg tagcacaaga atttttattt ttaaaatgaa aaagatgtga tataatggag
     3541 aaagataaat tgaggaggac gatatggcat tagcaaaaat tgtatttgcc agtatgaccg
     3601 gtaataccga agaaattgca gatattgtag cagacaaatt acgtgacttg ggcttggatg
     3661 ttgatgttga tgaatgtaca actgttgacg cttcagactt cttggaagca gacatcgcta
     3721 tcgttgcgac ctatacttat ggtgatggtg aattgccaga tgagatgatg gacttctacg
     3781 aagatctagc agatctcaac ttgaatggca aaatctacgg agtggtcggc tcaggagata
     3841 ccttctacga tgaattctgt aaggctgttg atgactttga ccgtgtcttt gtttcaacag
     3901 gagcagaaaa aggttctgag tgtgtcaaag ttgatctttc tgccgaggaa gaagatattg
     3961 aacgcttgga acaattcgca gaagaattgg ttgctaaagt aggataagca taaaagtgcg
     4021 ctgatgtaat caatcagtgc atttttctta tcgagagttg ggattttact agcctaattg
     4081 atggcttttt gatacaataa ttcaaataaa ggaggagact gtatggattt agatattatt
     4141 cgtcaagaaa tcgatcaaat cgacgaccaa attgtcaaac tgttagaaga acgaatgcat
     4201 ttagttgagg gggtggttgc ttataagaaa gcttcaggta aaccgatttt agatactaag
     4261 agagaagaag ttatttttga aaaggttagg agtcgtgtag aggacaagcg ctatcaggag
     4321 actattgtag cgactttttc ggacatactc aaacgttcgc gtgattatca ggatcaaaat
     4381 atcaaatgaa aaaagaacaa ttttatccgc taggaatttt tctagctgct atgttgggcg
     4441 gacttgtccg atatctagtt tccacctggt taccagccag tccagacttt ccttggggca
     4501 ctctctttgt caactatctg ggaattttct gcttgattta tcttgtcaag ggctatctgg
     4561 tctataaggg gactagtaag ggcttgattt tagcactggg gacgggtttt tgcggaggtt
     4621 taacaacttt ttccagccta atgcttgata ctgtgaagct gcttgataca gggcgttatc
     4681 ttagtttgat actgtatttg cttttgagta tcggtggagg cctgctttta gcttattttc
     4741 tagggaggaa gaaatggtaa tcgtctatct tgcaatcgcc tgtggcttgg gagcactcgt
     4801 acggtatttc ttttctcgct ataatcaagc ttctaaattg ccactcggaa cgctcatagc
     4861 taatctttta ggttgttttt taattggagt attctacaat catgtagagt ctaaggaagt
     4921 atatgctatt ctggcaacag gattttgtgg cggtttaaca actttttcga ccttgaatga
     4981 cgaacttcaa agactgctaa gcgataagaa ggtattttat tcttacctga ctttgactta
     5041 cataggtggt ttggttgcga tttttttagg aattttgcta taaatttctt tacttttttt
     5101 tagaaatttg gtaaactgta tcttgtgtgt aatggacgca caaaaataca gtttatccgc
     5161 tgaggaagtt tcctcaagat tgacaaagat aggagaataa aatgaatcca ttaatccaaa
     5221 gcttgactga aggtcaactt cgtacagata tcccatcatt ccgtcctggt gacactgttc
     5281 gtgtacacgc gaaagttgtc gaaggtaacc gtgaacgtat ccagattttt gaaggtgttg
     5341 ttatcgcacg taaaggtgct ggaatctcag aaaactacac agttcgtaaa atctctaacg
     5401 gtgtaggtgt tgagcgtatc ttcccaatcc acactccacg tgttgaaaaa atcgaagttg
     5461 ttcgttacgg taaagtacgt cgtgcgaaat tgtactactt gcgtgctctt caaggtaaag
     5521 cagctcgtat caaagaaatc cgtcgttaat tcgactaaaa aactctgctt ttcagcagag
     5581 tttttatcta gctcccttag ttcaatggat ataacaactc cctcctaagg agtagttgca
     5641 ggttcgattc ctgcaggggg cagtaattag acatcaaaaa ccgctcagct gagcggtttt
     5701 agtctattct ttccttttac agtacccatg ttcggatggc atgggcaacg ccggattcgt
     5761 catttgtttt ggtgatgtat ttggcgattt ttttgatttc tggatttcca ttttccatga
     5821 caacggggtt tccaacgact tccagcatgg cacggtcatt ttcttcatca ccgattgcca
     5881 tggtttcatc tttggtcaat ccgagttttt cagccaagtg agtaatggct gaacccttgt
     5941 ctacattctt tttaaggagt tcgaggtaga aaggagcaga tttgttgatg gagtagcgct
     6001 cgtaaaattc tgctggaatt ttttcaatcg cagcatcgag aatttctggt tcatcgataa
     6061 acatacattt aacaatttct ttgccaacca tttcttcagg ggtacggtag aagataggca
     6121 tgctgacgag ggttgattcg tgtacagtgt attttccgat attgcgattt gcagtataga
     6181 taccgtcctt ggtaatggca tgcatgtgga caccgagctt gcgactgagg aattccatat
     6241 ccagataatc ctcataggtc aaggattcgc tgataatctc atggccagta gcagtttctt
     6301 ggacaagggc accattgaag gtcaccacat agtcaccttg gtctctcaac tgcaagtcgt
     6361 ccagaagttt ggcaacacct gcgatggggc ggccagttgc aatcacgact ttgacaccag
     6421 cttctttggc atcttggatg gcagaaaaga cttcaggagt gatttccttt tggctgttga
     6481 caagggttcc gtcgatatca acggcaatta gtttaatact cataaatttc ctcttctagt
     6541 ttttatttgg ggtaaaatga tcgttctcaa tcaagtataa aaattgctgg gtaatgctag
     6601 caaagatact gttttgatct aacatttctt tcggaaaata gaaacgatta tctccgtgac
     6661 gactaccagc aagggattgg acgataggag acaggctaga gagttcggcc agttctccat
     6721 tcttttgtaa aatctcaatc tgtgtccgtg gattttcaga ttcgggacga tagatatcat
     6781 aagggaggtc aaagttctta tgaatggcag tatagtagtc gggatcaaag ccaatgtcct
     6841 caaccaattt tctcatgcta gcgagttggt cttgatcttc ttgtgaaaag gtaatggatt
     6901 taaagacctt gcggttgaca aagcgttgcg ataaatctgc gagaattttg tcaggactgg
     6961 tcatccagag ctggaagtag gtattcatca caccatcatc tagagccaga tagtcagaca
     7021 aggtcacatt tttttcaaag aaaggcagga ggtgtgggga agttcgtgca aagaagtctt
     7081 tgtccttagg gtagagttcc ttagcgcgct tgagaagatt ctgtaggaga acttccatag
     7141 cgcgtgttgc ggggtggaaa taaacctgca tgtacatctg gtagcgactg aggacgtagt
     7201 cttcgatggc gtgcatgcca ttgcgctgaa aggcgatacc attttcgata ggacgaatga
     7261 ctcggaggat gcgagtcagg tcaaattccc cataggatgc tcctgtaaaa taggagtcgc
     7321 gcaagagata gtccatgcga tctgcgtcaa tctgactaga aatgagctgc acgacctgct
     7381 tattaggata ggtatggtca atgacactgg ccaccttttc tgggaaatcg ggcgctactt
     7441 gtagcaagac ttggtgaatc tctgtctcag gattttgaat aatctcctga gtaatggctt
     7501 catggtctgt atcaaagaga tgttcaaaag tatgggagta ggcgccatgc ccaaggtcat
     7561 gtaggagagc agcggtcatg gtcaagagag actcggcagg attccattcc tcaggatatt
     7621 tttcttcaaa aatttctgtg atacgtcgtg caatctcata gactcccaga cagtgagaga
     7681 agcgactatg ctctccaccg tggaaggtat aactggaagt ccctagttgc ttgatccggc
     7741 gcaaacgttg aaattctttt gtattaatca agtcatagat gatttgatta ttgacatgga
     7801 tgtagttgtg aacagggtca cggaatactt tttcgttcat atgaccatta tagcaaaatc
     7861 ctgctctttt tggtaaaata gtaggacaag agacaagaaa gaggacctga tgtgaagatt
     7921 cggatgcgaa atacgattca gtttgatgag cagttggaag tgattgacca gctttatgat
     7981 gtggaagtgc atgaaaaggg agattatagc tatttactct tttataatga ggaaaaggaa
     8041 aaagtagtta ttaaatttca tggtcaagaa ctggtgatga gccgattttc taatcccaag
     8101 accattatgc gctttttaaa ggatagtgat agtttggcct atattcctac ccctatgggc
     8161 atgcaggaat ttatcattca aacgagccgt tatcaagttg ataggcaaaa gattgagcta
     8221 gcttatcaac tacaaaatca agaggggcat ccctttgcca gctatcaatt ggaaattact
     8281 tggggctagg atctcgtttt tctcaaatct actttctatc ttcaaggatt ggctccctag
     8341 tgtggtagat taggctattt tttggtataa taaaagttat ggaaatcgaa aaaaccaatc
     8401 gtatgaatgc gctctttgaa ttttatgcgg cgcttttgac agataagcaa atgaattata
     8461 tcgagctcta ctacgctgat gattacagcc ttgctgaaat tgccgaggag ttcggtgtca
     8521 gtcgtcaggc tgtctatgac aatatcaagc gaacagaaaa gattctggaa gattatgaga
     8581 tgaaattgca catgtactcg gactatattg tccgcagtca gatttttgat cagattttgg
     8641 agcgctatcc caaggataac tttctgcagg agcagataga aattttaaca agcattgata
     8701 atagagaata agaggaagaa aaatggcatt tgaaagttta acagaacgtt tgcagaacgt
     8761 ctttaaaaat ctacgtaaaa aaggaaaaat ctctgaatct gatgtccaag aggcaaccaa
     8821 agaaattcgc ttggccttgc tcgaggccga cgttgccttg cctgttgtaa aggactttat
     8881 caagaaagtt cgtgagcgtg cagtcgggca tgaggtcatt gatacactta atcctgcgca
     8941 acagattatt aaaatcgttg atgaggaact gacagccgtt ttaggttctg atacggcaga
     9001 aattatcaag tcacctaaga ttccaaccat catcatgatg gttggtttac aaggggctgg
     9061 taaaacaacc tttgctggta aattggccaa caaactcaag aaagaagaaa atgctcgtcc
     9121 tttgatgatt gcggcggata tttatcgtcc agctgccatt gaccagctta agaccttggg
     9181 acaacagatt gatgtgcctg tctttgcact tggaacagaa gtaccagctg ttgagattgt
     9241 acgtcaaggt ttggagcaag cccaaactaa tcataacgac tatgtcttga ttgatactgc
     9301 gggtcgtttg cagattgatg agctcctcat gaatgagctt cgtgatgtga aagcattggc
     9361 tcaaccaaat gaaatcttgc ttgtcgttga tgctatgatt ggtcaggaag cagccaatgt
     9421 tgcgcgtgag tttaatgctc agttggaagt gactggggtc atccttacca agattgatgg
     9481 cgatactcgt ggtggtgctg ctctgtctgt tcgtcacatt actggaaaac caatcaagtt
     9541 cactggtaca ggtgaaaaga ttacggacat tgaaaccttc cacccagacc gcatgtctag
     9601 ccgtatcctt ggtatggggg atatgctcac tttgattgag aaagcttctc aggaatacga
     9661 tgaacaaaaa gcccttgaaa tggctgagaa gatgcgcgaa aacacctttg attttaatga
     9721 tttcatcgat caattagatc aggtgcaaaa tatggggccg atggaagact tgctcaagat
     9781 gattccaggt atggccaaca atccagccct tcaaaacatg aaggtggatg aacgccagat
     9841 tgctcgtaaa cgtgccattg tgtcttcgat gacacctgaa gagcgtgaaa acccagattt
     9901 gttaaatcca agccgtcgcc gtcgtattgc tgctggttct ggaaatacat tcgtcgaagt
     9961 caataaattc atcaaggact ttaaccaggc taaacagctc atgcagggtg ttatgtctgg
    10021 ggatatgaat aaaatgatga agcaaatggg gattaatcca aataaccttc ctaaaaatat
    10081 gccaaatatg ggaggaatgg atatgtctgc ccttgaagga atgatgggac aaggcggtat
    10141 gcctgactta tcagctctcg gaggagcagg aatgccagat atgagccaga tgtttggtgg
    10201 cggtttgaaa ggtaaaattg gtgaatttgc catgaaacag tccatgaaac gtatggctaa
    10261 caaaatgaag aaagcgaaga agaaacgcaa gtaagacaag agattgatgc aaatctcatt
    10321 tgatgagaaa ataaagtaaa aatttctatg ataaaacgta cagtatcaag gttttagaat
    10381 atctgatatt atacgttttt tgattttaat aattttgtta agacactttt attatggtat
    10441 gcgaaaaatc cactcagctg tctgagtgga ttaggtgtat ttagactctt agtctttatt
    10501 ttcgtatggc aagatcaagt tcaagatgat tcctgtcatg gctgaaaggg cagtacctga
    10561 aagtgtaact ggaccaagtt taaggatagc tcctccaagt ccaagaacca acatagcact
    10621 tgcgatgatg aggtttcgca tttgagcgaa atcaacacgt tctttaatca agactttcaa
    10681 accattgctg gcgataaccc catagagaag gattgacata ccaccaagta cagcgtttgg
    10741 aatagttgaa atcaaggcag tgaatttacc aaggaagctg agggcaatcg cgatgaaggc
    10801 agcgttacgg ataactgaga cagaagcgat acgagtcata ccgataaccc ctgtattttc
    10861 tccgtaagtt gtattggctg gtccaccaag gaaggcagaa acagaagttg cgataccgtc
    10921 accaagaaga gtacggtgaa gacctggttc ttttaagaat tgacgaccac agatttgacc
    10981 caaaacagta tggtctccga tatgttcaga aattgttacg atagcgattg gcaagatagc
    11041 gatggcttct ggaccaaagt aaagattgta ctctttaaag gcaccacctg tgctaaatgg
    11101 caagtagaaa ccaggaattt cgaaccagtt ggctttaaga actggtgtaa agtcaaccaa
    11161 gccaagagtt agtgcgaaaa ggtaaccacc gataatggca aagaggaatg gaatgattcg
    11221 taggaagcct tttccttttg tattgataaa ggcagcaatt aggaaagtaa caacggctac
    11281 cagagcattt ttccaatttc cgtctgctac aagacctgca ttggtaacag ctgaacctgc
    11341 aagtccaaga ccgataacga tgatcatagg accgataatg attggtggca agagtttatc
    11401 aatccatttt gttcctacaa atcggatgct ggtagcaaca aggacataga ccaaaccagt
    11461 caagataacc cctgtttggg cagcagatac atcccccccc atttctttca tagccagtga
    11521 catagctgtg ataaaggcaa atgaagaacc tagataaact ggaactttaa aaccagtagc
    11581 aatcatgtag atgagtgttc caacacctga agcaaaaagg gcaacagata caggcattcc
    11641 caaaatcaat ggtaccaaga tggtcgcacc aaacatggcg aaaacgtgtt ggaaactaag
    11701 gagaattcct tttccatccg aaggacgttg gtcaacgtct agtaacaaat caacagttga
    11761 ttcttgtttc atataaacct cacttttggg catcagaaaa gagcccatta ttttacagca
    11821 ataggccctc agagtaagac ttctctaaaa tctagacttt aaagagtttc aaatattttt
    11881 gcgtcttcgt cacctcacgg gatgacatta aaaacctttg cttaggatag tatagcagaa
    11941 aaaaatgatt ttgtaaatca ttttttcccg agcctagaaa taaaagagcg aggctgattt
    12001 tgtaaacatt tgtttactaa aaaatttaaa gtgggcgttt atttggcata ccagccttac
    12061 gtggatattt atttggtgtt tcttttttct tttctaccac tgtgatatag cgcggatctc
    12121 tattcggtag ggcgtagctg agattgtctt cgaccttact aaaaaggaga ttgagggcat
    12181 tcttagcttc taataattcc tcaggcgcat tgctggcctt gagtgccaat agtttgccac
    12241 caaccttaag gtagggaata gtcaattcag ataggacctg catacgggca accgcacgag
    12301 ctgttacaaa atcatattga gcacggaagt tcttgtcttg ggcaaaatct tcggcacgtc
    12361 cgtggtagaa atgaactccg ttcaaatcca gttcttgagc caagagttgt aggaagttga
    12421 tgcgcttatt gagtgaatca ataatggtca catctaactc cggatagaga attttcattg
    12481 gtagactagg aaatcctgcc ccagccccga tatcaagaag tttgatagtt tcattgggaa
    12541 tcaaaccttg aagaatgggt gcaatcgaat cgtaaaaatg tttgagataa acttcttcct
    12601 tgtccgtaat cgccgtcaaa ttaatcttct cattccactc gaccaagagc tcaaaataac
    12661 gttcaaattg ttctttttgc tggtccgaaa gtggaagatt ctgctcggca agcaagttgt
    12721 aaaatgtttt tggtttcata gttatttcct tctttagtat catcttattt taccacaatc
    12781 atagaaaatt tgatatactg gtactaatct aaaagcagaa aggacttata ttatgacttg
    12841 gattattctt ggagttttag ctcttgttgt tatttttgtg attgttagct ataacggttt
    12901 ggttaaaaat cgtatgcaaa ccaaggaggc ttggagtcag attgatgttc agttgaaacg
    12961 tcgaaatgac ctcttgccaa acttgattga gactgtaaaa ggttatgcca aatatgaagg
    13021 ttctaccctt gaaaaggtgg cagaactacg taaccaagtg gcggcagcga cttcaccagc
    13081 agaagctatg aaagccagtg atgccctcac tcgtcaggtt tcaggtattt ttgcagttgc
    13141 agaaagctat ccagatttga aagctagtgc taactttgtt aaattgcaag aggagttgac
    13201 aaacacagaa aataaaattt cttactctcg tcaactctat aacagtgttg tcagcaacta
    13261 caatgtaaaa ttagaaactt tcccgagcaa tattatcgct ggaatgtttg gatttaaagc
    13321 ggcagatttc cttcaaacac ctgaagagga aaagtcggtt cctaaagttg attttagcgg
    13381 tttaggtgac taagatgttg tttgatcaaa ttgcaagcaa taaacgaaaa acctggattt
    13441 tgttgctggt atttttccta ctcttagctc ttgttggtta tgcggttggt tatctcttta
    13501 taagatctgg acttggtggt ttggttatcg cactgattat cggctttatc tacgctttgt
    13561 ctatgatttt tcaatcgaca gagattgtca tgtccatgaa tggagcgcgt gaggtggatg
    13621 agcaaacggc accagacctc taccatgtag tggaagatat ggctctggtc gctcagattc
    13681 ctatgccccg tgttttcatc attgatgatc cagccttaaa tgcctttgcg acaggttcta
    13741 atcctcaaaa tgcggctgtt gctgcgactt caggtctact agctatcatg aatcgtgaag
    13801 aactagaagc tgttatggga catgaagtca gtcatattcg taattatgat atccgtattt
    13861 cgactattgc agttgccctt gctagtgcta tcaccatgct ttctagtatg gcaggtcgta
    13921 tgatgtggtg gggtggagca ggtcgcagac gaagtgatga tgaccgagat ggaaatggtc
    13981 ttgaaatcat tatgctagtg gtttccctac tagctattgt actggcacct ctcgctgcaa
    14041 ccttggttca gctcgctatt tctcgtcaga gggaatttct ggcagatgca tctagtgtcg
    14101 agctgactcg caatccccag ggaatgatta atgccctaga taagttggac aatagcaaac
    14161 ctatgagtcg ccacgtcgat gatgctagca gtgcccttta tatcaatgat cccaagaaag
    14221 gtggggggtt ccaaaaactc ttttataccc acccacctat ctcagaacgg attgaacgtt
    14281 taaaacatat gtaaaatgaa ggctggaaaa aagtctttaa aatctgaaaa acgcataata
    14341 tcaggtgtga aaacttgata ttatgcgttt tactatggga agatttactt ctttttctcc
    14401 taaaattgtg tttttgcccc acctatctgc tatgttgcaa atttataaat cttctaaatt
    14461 aactagcttc aaaccgtgtt ctgtcatgcg atagatgatc gagcagactt cttttaagaa
    14521 acgacggtca tgcgaaacag tgatgagacc gccaggataa gtggcaaaga gttttctgat
    14581 ttggggttga gaagtgggag aaaagtttcg tgtgggttca tccagcagga gaaagtttgg
    14641 tttgcgcagg actaaatcca aaagcaggag ttttccctgt tgtccgccag ataaggagcg
    14701 aatttgatgc tgcatttctg gataactgaa attgagacta gctaggtgag attggatttt
    14761 ctgtagttcc tctttttccc cagttttact gagataggct attggggata aatccaattg
    14821 cagttttttg tggtaatctt gtggcataaa accaagtgaa atctctcttt tatcattcag
    14881 aagtctctgt aacttggcta acagagttga tttcccaaca ccatttggcc cgataatacc
    14941 gattttttct tggccacgga cagttagttg tagtttttga accaaaactc ggtcgtcaat
    15001 ggacaaattt tctttttcca gttggactaa gactttagaa gctggtaatg gttggatgtc
    15061 tgaaaagaaa agttggattt gttcctcttc aagtggcttt tgagtcatgg actgagctgc
    15121 cttttcgtag cgtttttctt gtgagaggac agttttcatc tttttagcca ataggcgacc
    15181 ggcagtacta tctttggtag ctcgaagcgc agtttctaca ctttgcttga ctctccgatg
    15241 tttttccatg gttttatcgt aggctctttg gttgttagca gcttgctgac tttgtttggc
    15301 aaaattagcc tttctctgct cactatagct atcatagtct aaatgctcta ctagcgtttc
    15361 cgcttcttta cggtgtttga ccagtcgcaa gtgaacaata gtgtctgccg tttcagaaag
    15421 aaagtcttca tcatgggaaa tgaaaataac ggtttgcctg gtcttttgaa tctggccttt
    15481 tagccaatca actgtctcaa ggtctaggtc atttgaaggt tcatctaaaa atagaatctc
    15541 aaagggtttg gctaactcat ggataagctg aattttcaaa gcttcgcccc ctgatagatt
    15601 gccaatcttt tggtcacttg cgaaacgatt gctatcaaaa tgcaattcct ccgccaaacg
    15661 atagaggata ctgtagtcta aatcaataga atctaaaaag aagtagtcgt gtaaagtttt
    15721 ctttttcagc tcctcgggaa gtttttgagg aatgtaggcc agtgactgat agtcagattg
    15781 gatgtttccc ttgatagtga aatcagacaa agcttccccc attaaaattt taagtaaggt
    15841 tgatttgcca tttccttctt caccaataat agcaaccttt tccccgtctt ggatggtcat
    15901 gcttaggtca gatacaagat ctcgtaaatc tttgttttgt gtgatggtta gatgattgat
    15961 ttttatcata tgatttccct ttctagaatg ttcatagtgc ataacaaaaa gctctacttt
    16021 acctagtaga gcccaaagtc tatgtcaaaa aaactctatt aacatgccag aaaaagagca
    16081 taaaagagca cacaaaaaga gacaaaaaca agatctacta aataaaggtt ctttatttga
    16141 tagacttagt tgttcatgtc tcccttacct ccgagtatta gtatctttat attatacctt
    16201 taaggaaatt ttgtcaacag aaaactggaa attctatgct ctaaaatcca aaaacaggtc
    16261 catagagact tagtacgtgt ttgacatgct cgtaatggaa tttatcatag tttcgccaag
    16321 cagtgcgtgc ttgatcgttt agttttaggc tacccagtcc aatcagaaga ctggtgggtt
    16381 ggtaaaattt ctcaagatca attaagatac tgttgttcaa cttttccgtt ttttgagctc
    16441 ttgcatagta gtgtttagca gctcttgtag tcgaatatca tctgccgtac cctgtttaca
    16501 gttttggtag cttttattta acttggatag gagttgaatg agtttcttgt cttccatgtg
    16561 agcatcctcc ttgatctgat gtactctttc cctatagtat agcactaaaa aataaaacta
    16621 tcatagtaaa tatgttaaaa tttgaatttt aattacaaag tttggtgtgc tgatttgtag
    16681 ccttttcatg gtataatcaa gagagtaaat ctttatggag gaagtatgaa attaaatatt
    16741 caagaaattc gtaagcagtc tgaaggtttg aactttgaac aaacgttaga tttagttgat
    16801 gacctgcgtg cacgtaatca agaaatttta gatgtaaaag atatccttgc agttgggaaa
    16861 gtacaatatg aagaccgtat gtatttctta gattatcaac tatcttatac cattgttctt
    16921 gcttcgagtc gcagtatgga gccagttgag ttagttgaat cttatccagt cacggaagtt
    16981 ttcatggaag gcgcaactaa ccagctagat caagaagttt tagatgatga cttggtcttg
    17041 cccatcgaaa atggggcgct tgaccttgct gagagtgtat cagacaatat cctgctaaac
    17101 attcctatca aggtcttgac ggctgaagaa gaagctggtc aaggatttgt ctcaggaaat
    17161 gactggcaaa tcatgacaga ggaagaatac caagctcaac aagcagtaaa gaaagaagaa
    17221 aacagtcctt ttgctggctt acaaggacta tttgacggag atgaataatg gtcttgtcaa
    17281 aaaaacgagc acgaaaggtg ctagaagaaa tcattgccct cttcccagat gccaagccta
    17341 gtcttgattt taccaatcat tttgaactcc tggttgcggt catgttatca gcccagacga
    17401 cagatgcagc ggtaaataag gccacaccag gtctctttgt tgcctttcca acaccccaag
    17461 ctatgtctgt agcgacagag agtgagattg cttcacatat ttctcgcttg ggattgtatc
    17521 ggaataaagc taaattcctt aaaaaatgtg cccaacagtt actagacgat tttgatggtc
    17581 aagtccctca gacacgtgaa gaattggaga gtttggcagg tgttggtcgc aagacagcca
    17641 atgttgtcat gagtgtagga tttgggattc cagcctttgc agtggatact catgtggagc
    17701 gtatttgcaa acaccacgat attgtcaaaa aatcagcgac gccacttgag gtggaaaagc
    17761 gggtcatgga tatcttgccg cctgagcagt ggttagctgc ccatcaggcc atgatttatt
    17821 ttggaagagc catttgccat ccaaaaaatc cagagtgtga ccagtaccca caattatatg
    17881 attttagcaa tttgtaagat gctacattga aactttttgc ttgattttaa gcatgctttg
    17941 tgctatagta aatgataact aaatattcct ttaaacctgt cccgtgaggc aggcaaggag
    18001 cgcgataaag tagaagggtg aagtctatac tgtgtgcagt agggctcgct tggctataaa
    18061 tttcaagtct ccttgtttaa ggagactttt ctttttggag gtttgtcatg aaaacaaaag
    18121 aagttgtaga cgaattgacc gtcaaacgag cgattacgcg tattacttat gagattatcg
    18181 aacgcaacaa agatttgaat aagatcgtct tggctggtat taaaactcgt ggtgtcttta
    18241 ttgcccaccg aatccaagaa cgtttgaagc agttagaaaa tctttcagtt cctgttgtgg
    18301 aattggatac taaacctttc cgtgatgatg ttaaaagtgg agaagatact tctttggttt
    18361 ctgtcgatgt gacagaccgc gaagttatct tggtggatga tgtgctctat acaggtcgta
    18421 ccatccgtgc tgctattgat aatattgtcg gtcatggtcg tcctgcgcgt gtgagtttag
    18481 cagttctagt cgatcgtgga catagagaat tgccaatccg tccagattac gttggaaaaa
    18541 atatcccaac cagtcgttct gaagaaatca tcgtagagat gacagaactt gatgaccaag
    18601 acagagttct gattactgaa gaagcttaga aagttaaagg agtagccatg tcagaaaatc
    18661 aacaagcatt gaaccatgtg gtgtccatgg aagacctcac tgtcgatcaa gtaatgaaat
    18721 tgatcaagcg aggaattgag tttaaaaatg gagcccagct tccctatgaa gaccatccga
    18781 ttgtttccaa tctcttcttt gaggattcta cacggacaca taagtccttt gaagtcgcag
    18841 agattaaact tggattggaa cgacttgact ttgatgtgaa gactagttcg gttaataagg
    18901 gtgagacact ttatgacacc attttgactc tgtctgcttt aggagtggat gtctgtgtga
    18961 ttcgccatcc agaggtcgac tactatagag aattgattgc tagtccaacg attacgactt
    19021 ccatcatcaa tggtggagat ggttcgggcc aacaccctag ccagagcttg cttgatttga
    19081 tgaccattta tgaggaattt ggccactttg agggtcttaa agttgctatt gcaggtgact
    19141 tggaccactc acgcgttgcc aaatccaata tgcagatttt gaaacgcttg ggatctgaac
    19201 tctttttcgc tggacctgag gaatggagaa gtcaagagtt tgcagactat ggacagtttg
    19261 taaccattga tgaaatcatt gatcaggttg atgtcatgat gtttctccgt gtgcaacacg
    19321 aacgccatga tagtggagct gtattttcaa aagaagacta ccatgcccaa catggcttga
    19381 ctcaagaacg ttacgatcgt ttgaaagaaa cagcaatcct catgcaccca gctccaatca
    19441 atcgtgatgt agaaatagca gaccacttgg ttgaagcacc aaaatcacgg attgtccaac
    19501 aaatgaccaa tggtgtcttt gttcgaatgg caatcttaga atccgtacta gcgagtagaa
    19561 acgccaacta aaacacaaga cgttaaaaga cgccagtgag cgtccacgag aggtgaaaat
    19621 atgacaaaaa gaattctagt attagaagat ggcacagttt ttgaaggcaa ggccttcgga
    19681 tcagatattg atgtaacagg cgaaatcgtc tttaatacag ggatgaccgg ctaccaagaa
    19741 tccattacag accagtctta taatggacaa atcttgacct ttacttatcc tttggtagga
    19801 aattatggta ttaatcgtga tgattatgaa tccattattc caacttgtaa gggagtcgtt
    19861 gtttttgaag aagcgcgtag agctagcaac tggcgcaacc aaatgacctt ggatgaattt
    19921 ttgaaagcca agaaaattcc agggatttca ggaattgata cgcgtgctct taccaagatt
    19981 atccgtaagc atggtactat gcgtgcaacc ttgacccatg ttggggacag tatggaccat
    20041 gtgacggacc agctccaagc aacagtttta ccgacagaca atatcaaaca ggtttctact
    20101 aaaacgtctt atccagctcc aggagttggt ttgagcgtgg tgctagtgga ctttggtctc
    20161 aagcactcaa tcctacgtga actttctaaa cgcaactgta acgtgacagt tgttccttat
    20221 tcgacaacgg ctgaagaaat tctccatctc aatcctgacg gagttatgtt gtcaaatggt
    20281 ccaggtaacc cagaagacgt tccacaagca ctcgacatga ttcgcggtgt acaaggaaaa
    20341 attccaatct ttggtatttg tatgggacac caactctttg caatggcaaa cggggctaag
    20401 acctataaga tgaagtttgg ccaccgtgga ttcaaccatg cggtacgtga aatcgcaaca
    20461 ggacgagtag atttcaccag ccagaaccat ggttatgcag tcagccgcga ggatttgcca
    20521 gagcacttga ttattaccca cgaagaaatc aatgacaagt cagtggaagg tgtgcgccac
    20581 agataccaac ctgctttctc tgttcaatac cacccagatg cagctcctgg accacacgac
    20641 gctagctacc tatttgacga gtttatcgag atgatggaaa tttttaaaca atcaaactaa
    20701 gaacgagtaa aagctcgtcg gagaatttat gtaactgaac acggacggaa agctcagaat
    20761 ttagagaaac caacttggat tgtcaatcct tccttgattt cctaaaattc aatcgctttc
    20821 tattcgtcct ttgtatctta tttaatgtcg ccctgagagg cgacgaatag aaaggagaag
    20881 atacattgtt cgcggaagtg aacacgccct aagaactgtg tgaaaaagat aaacatcgtc
    20941 ttgacgctga aggcgtctgc gccgagtttc ctattttcac tgtgttcttt acgggctttg
    21001 tatcataaac tatgcctaaa cgtactgata ttcaaaaaat tatggtgatt ggttctggtc
    21061 cgattattat tggtcaggct gctgagtttg attacgctgg gacccaggct tgcttgtcgt
    21121 tgaaagagga aggttatgag gttgttttgg ttaactcaaa tcctgcaacc atcatgacgg
    21181 acaaggaaat tgctgacaag gtttacattg aaccgattac acttgagttt gtgacacgta
    21241 ttcttcgtaa ggaacgtcca gatgccttgc taccaacact cggtggtcag acaggtctca
    21301 acatggccat ggaattatct aaaaatggta tcctagacga gcttggcgtt gaacttctgg
    21361 gtaccaaatt atctgccatt gaccaagcgg aggaccgtga cctctttaaa caattgatgg
    21421 aagagcttga gcaacccatt ccagaatctg aaattgttaa cacagtagaa gaagcagttg
    21481 cctttgcagc gacaattggc tacccagtca tcgttcgtcc agcctttacc cttggtggta
    21541 ctggtggtgg tatgtgtgcc aacgaaaaag aattgcgtga aatcactgaa aatggtttga
    21601 aattgtcacc tgttacccaa tgtttgattg agcgttcgat tgccggtttt aaggaaattg
    21661 aatacgaagt gatgcgtgac tcagctgaca atgccttggt tgtttgtaac atggaaaact
    21721 ttgacccagt tgggattcac acaggggatt ccattgtatt tgcccctgcg caaaccatgt
    21781 cagactatga aaaccaaatg cttcgtgatg cgagcttgag cattattcgc gccctcaaga
    21841 ttgaaggtgg atgtaatgtt cagctagctc ttgatcctaa cagcttcaag tattatgtta
    21901 tcgaagtaaa ccctcgtgta tcacgttcgt cagcccttgc ttctaaagcg acaggatatc
    21961 cgattgctaa gttggctgcc aagattgcag taggtttgac cttggatgag gttataaacc
    22021 cagttacagg ttcaacctat gccatgtttg aaccagccct tgactacgta gttgctaaga
    22081 ttccacgttt cccatttgac aagtttgaaa agggtgaacg ccgtctcggt acacaaatga
    22141 aggcgactgg agaagtcatg gcaatcggtc gtaacatcga ggaatctctt ctcaaggcct
    22201 gccgctccct tgaaattggg gtgcaccaca atgaaatacc tgaacttgca gcagtttctg
    22261 atgatgcctt gattgaaaag gttgtcaaag cccaagatga ccgtctcttc tacgtatcag
    22321 aagccattcg tcgtggctac acacctgaag aaattgcaga gcttacaaaa attgatatct
    22381 tctatcttga taaactcttg catatctttg aaattgagca agaattgggt gctcatccac
    22441 aagatctaga agttttgaaa acagccaaac ttaatggttt ctcagaccgt aagattgctg
    22501 aactctgggg aacgactgat gatcaagttc gccaacttcg cttggaaaac aagattgttc
    22561 cagtttataa gatggtagat acttgtgcgg cagagttcga ctctgaaacg ccatatttct
    22621 attcaaccta tggttgggaa aatgaatcta tcagatctga taaagaatct gtacttgtcc
    22681 taggttcagg tccaatccgt atcggtcaag gggttgagtt tgactacgca accgttcact
    22741 ctgttaaggc tatccaggca gctggttatg aagctatcat catgaactca aacccagaga
    22801 ccgtttcaac agacttctct gtatcagata agctttactt tgagccattg acattcgaag
    22861 atgttatgaa cgtcattgac ttggaacaac caaagggagt tatcgttcag tttggtggtc
    22921 aaacagccat caaccttgcg gagccattgg caaaagcagg tgtgaccatc cttggtacac
    22981 aggttgctga cctagaccgt gccgaagacc gtgacctctt cgagcaagct ctcaaagaat
    23041 tggatattcc acagccacca ggacaaacgg ctaccaatga agaagaagca gctcttgcag
    23101 ctcgtaagat tggcttccca gttcttgtcc gcccatctta tgtacttggt ggacgtgcca
    23161 tggaaatcgt tgaaaacgaa gaagaccttc gttcttacat gcgaactgct gttaaggcta
    23221 gtccagatca cccagttctt gtcgactctt atatcgttgg gcaagagtgc gaagttgatg
    23281 ccatttcaga tggtaaagat gtgctcattc ctggtatcat ggagcatatc gaacgtgctg
    23341 gtgtccactc aggtgactca atggctgttt acccaccaca aaccttgtcg caaaaggttc
    23401 aggagaccat cgcagactac accaaacgct tagcaatcgg tcttcactgc cttggaatga
    23461 tgaacatcca gtttgttatc aaggatgaaa aagtctacgt tattgaggtc aatccacgtg
    23521 ccagccgtac tgttccattc ctatctaagg taaccaatat tcctatggct caagtagcga
    23581 ccaagctcat tcttggtcaa agtttatcag aacttggcta ccaaaatgga ctttaccctg
    23641 aaagcacccg tgttcatatc aaggcacctg tcttctcctt taccaaacta gctaaggtag
    23701 acagcttgct cggtcctgaa atgaagtcaa caggtgaagt tatgggttct gatgctactt
    23761 tggaaaaagc tctctataaa gcctttgaag cttcttatct acacttgcca acttttggta
    23821 atgtcgtctt taccatcgct gatgatgcca aagaagaagc cttgaacttg gctcgtcgtt
    23881 tccaaaacat tggttatgga atccttgcga cagaagggac agcagccttc tttgctagtc
    23941 atggcttgca agcccaacct gttggtaaga ttggtgatga cgataaggat atcccaagtt
    24001 ttgtacgcaa aggaagaatt caagctatca ttaacacagt aggaacaaaa cgaactgctg
    24061 acgaagatgg tgagcaaatt cgtcgttcag ccattgaaca cggggtgccc ctcttcacag
    24121 cgctagatac agctaatgcc atgcttaagg tacttgaaag tcgtagcttt gttacagaag
    24181 cgatttaaat agaaaaataa gatatagcag actgaattta gaacagtaca caggaatact
    24241 aaaatatttc tataaattaa tttgaatttt ctaattgatt tgttcgcatc ttatttcaat
    24301 ctactataga aaaaagtctt taaaattata aaacgcatca tatcaaggtt tttcaaaaac
    24361 cttgatatga tgcgttttat tgtgggaata tgtatttcat tttctactaa aattatgttt
    24421 ttgaataacc tctatcttag tagtttgtat aatccccctc aatcagtttt tgcgataagc
    24481 tttaatgcta tgactatacc actcttgcat ttcttttgat ggtggtgtca tataatcgcc
    24541 atacatctgg gttaaaaatt ggtcatattt tttgggaaca ggcaacatac ggccctcaaa
    24601 ctcagttaaa atcagttctt taaaggtatc aactgggaag atttctttca tcccttcctt
    24661 accgatccca actcctcctt catattgagg aatgttggtt acagcatttt tgactagttg
    24721 atcaattttc ttgtaaaagt agcgaggatt gacaaatcgg agagcgtacc agctacataa
    24781 tctaagaaaa tcttttagtt tgctatcacc gtgaactgct cgtgattttt tgatataagc
    24841 tagttgacga agagccacat acttatagct cttgtcgaca atgctcaagt ctgtaaatcg
    24901 atcaattggg aagacatcga tgaaaaggct ggtatcatga cgcttgtact taacatggtc
    24961 ttctataaca gtagaagtgt ccaaaatcga tgcgaaatta tggaagtacc aagaagatgt
    25021 atcgtaggaa agaaccttgt agcgagggtg attttcttct tcaataatct tcagtaaacg
    25081 ctcataatcc tcacgataaa gggaaatatc aatatcatca tcccaaggaa tcataccttt
    25141 gtggcggatg gctccaagca tggttccata actgagaaaa taaggaatat catgtttctt
    25201 acaagtctca tcaatatagt ccagcagggc tagttgaatt tctttaattt cttttttttc
    25261 taaatattgc atcctaatcc tccaatttat aagcgtgaaa ttcatgactg tagaagcgtt
    25321 tttcttctgg tggtagggtc atataatctc cataaaattg tgtcaaaata gtatcaaatt
    25381 tttcaggtgc aggaaggctt aaattctcaa agggtaaatc gattatttta tcaaaggtac
    25441 cacttgggaa gacttccttt tccttaaatt ttgaagggat aaaagccata tactgcccat
    25501 tttcacgact atatttttga atttctttct cgattttatt tgcaaaataa cgaggagaaa
    25561 ctggtcgaag gagcaaccaa aaggctgttc gtatccaatc ttttaaaagg ctatccttat
    25621 agacaatatt tttatgttta ctgaaagaca gcagtttgaa gctttccagt ttataacaag
    25681 tatcaatgac cttaggatca tcaaagcgat ccatagggaa aatatcgata aagataccag
    25741 actcataggt ttttgtattt cgagtatcaa taattttagt cgtactgtcg gttatcttga
    25801 taaagttgtt aaagtagttc ttatcagttt ctaaggatag gagttcatac ttgctttttt
    25861 ccttttgaaa aatgttaata aatcgttggt agtcttctct aggcatggat aaatcaatat
    25921 cgtcgtccca agggataaag ccctcatgtc gaaccgcccc aatcagagta ccgtagttaa
    25981 taatatagtt gatattgtgc tttttacaga gagtatcaat ataatccaaa atttctaatt
    26041 caatttgttt ggcatcttca acggttagtt gtttcatttt aaactcctat gattttttaa
    26101 atttattttt taaggctaga acatggttta aaaattcata gaaaatgcta tcttttgtga
    26161 agacaagtag actaatataa gagatagctg atagcaagat aatcaaacca gtattaatca
    26221 aaaatggcaa attaatgacc atatccacag gatacacgaa attaatcagg aaataaattg
    26281 ctacaaagga aagtgaaaag agagagtatc gaacagtata gctaaagata tgtcccaagt
    26341 ggatgagttg ttttctatgg atgaaaatga tatagaaaac aagtagagaa gcctctgata
    26401 acatagttgt cagtaagtag tattcgggag ccacgatacg gttgaaaaag aggagactat
    26461 tcaagcccaa attgagtagc ccagcaaaga ctgtataaac tgtgatacgt ttttcatagc
    26521 cattggtaaa gagaatttgg gaaccaagaa tggtatctaa ggccaggata atcgtacgaa
    26581 aagcgaagag agaggtcaag atgccgcctc cgatatattt ttcactaccg taaagtagga
    26641 tggcatttgg tcctaaaacc atgagtccaa aactcagtgg aatgataaag aagttaaaga
    26701 ttcgactacc tctattaacc agagaaacat aggcttcttt gtctcctttc cccagatagt
    26761 aactgagacg aggcacactc actccaattg cacctgttac aaccccagct ataacggtca
    26821 caattcgctg agctatggta tagtaactaa cgttgacatc aatccctgtt ttaacgagga
    26881 agaggcgatc taaaaaagtg aagagcatat tggcattggc aaagactaac atggctgtca
    26941 gagggagaaa gagtggttta aaatcactta ggtgaatctt aacaagtttg atgtctcttt
    27001 taatccaaaa ataactaatc aggtagttaa tcagcgtcga taaactcatc acaagtgtat
    27061 agacaacaat atcgtgttca tttttaacaa ataagaaaat agagaccagc atcaggatac
    27121 ggatgaaggc agttttgtaa aagagaaaac tgtaattttc cagagcttca ttgacccatt
    27181 cgattgaaaa aatctgggca atgagttgaa tccccataac aaggtagacc tttttgatga
    27241 ttggattatc agtaaagaag agaggatagg ctaggatata gacagcagtg gtcaaaatcg
    27301 tacaagcgat gcacaaataa aaaagactag aaaaggttct gttaagatct tttttgttat
    27361 ccttgacatt actgatagcc cttaaaccgt agttatagac accataagtt gcaaagggca
    27421 agaaaaatga caaaatagtg tcgactgagt tgaagtaacc atagtcagtt cggtccaaga
    27481 cacgcgcgac ataggttcca gttaggatgg gaaaaataat attcaagaca cgaattccca
    27541 tgtaagatag agcatttaat tttatacttt tcattcaatt tacctcgttt ttcattatat
    27601 cataaagtta gctaataaga aatgaagggc agtaagtcaa gtaatcactt tgaagtttca
    27661 aatcttaagt tttaagtttt ctttaaggaa agtatattat tctgaaggac tctaaaattt
    27721 cgcagccatt tattagtaat tgctacagaa ttcctagtca ttactagaaa tggactagtt
    27781 tctttgaata atagaactgc ataattctcc tattctagaa ggggaggacc agtatttctt
    27841 ttatgatagg actagattgt ggtataatag agagaataag tttttttagt aagacaaagg
    27901 agaaaataga tgatttatgc aggaattctt gccggtggaa ctggcacacg catggggatc
    27961 agtaacttgc caaaacaatt tttagagcta ggtgatcgac ctattttgat tcatacaatt
    28021 gaaaaatttg tcttggagcc aagtattgaa aaaattgtag ttggtgttca tggagactgg
    28081 gtttctcatg cagaagatct tgtagataaa tatcttcctc tttataagga acgtatcatc
    28141 attacaaagg gtggtgctga ccgcaataca agtattaaga acatcattga agccattgat
    28201 gcttatcgtc cgcttactcc agaggatatc gttgttaccc acgattctgt tcgtccattt
    28261 attacacttc gcatgattca ggacaatatc caacttgccc aaaatcatga cgcagtggac
    28321 acagtggtag aagcggttga tactatcgtt gaaagtacca atggtcaatt tattacagat
    28381 attccaaatc gtgctcacct ttatcaagga caaacacctc aaacattccg ttgcaaggac
    28441 ttcatggacc tttatggatc tctttctgat gaagagaagg aaatcttgac agatgcatgt
    28501 aaaatctttg tgatcaaagg aaaagatgtg gctttggcca aaggtgaata ctcaaatctg
    28561 aagattacaa ccgtaacaga tttgaagatt gcaaaaagta tgattgagaa agactagtaa
    28621 aatgattaat caaatttatc aactaactaa gcctaagttt atcaatgtca aatatcagga
    28681 agaggctatt gaccaagaga atcatatcct tatccgtccc aactacatgg ctgtctgtca
    28741 tgcggatcag cgttactatc agggaaaacg tgatcccaag attttgaata aaaagcttcc
    28801 aatggcaatg attcacgagt catgtggaac cgtcatttct gacccgaccg gaacctacga
    28861 ggttggtcaa aaagttgtca tgattcccaa tcagtctcct atgcagagtg atgaagaatt
    28921 ctatgaaaac tacatgacag ggacccattt cttgtctagt ggatttgatg gctttatgag
    28981 agagtttgtt tctctcccta aagatcgtgt ggtggcttat gatgctattg aagatacggt
    29041 tgcagccatt acagagtttg tcagtgtggg catgcacgct atgaatcgtc tattgactct
    29101 tgctcatagc aagcgggagc ggatcgccgt tattggagat ggaagtttag cttttgtggt
    29161 tgccaatatt atcaactata ctttgccaga agcagagatt gtggttattg gtcgtcattg
    29221 ggaaaagttg gaactcttct catttgccaa agaatgctat attacggata atattcctga
    29281 agatttggcc tttgaccatg cttttgaatg ttgtggtggt gatggtactg gaccagctat
    29341 taatgacttg attcgctaca ttcgtcctca gggaacgatt ctcatgatgg gagttagcga
    29401 atataaagtc aatctcaata ctcgcgatgc cttagaaaag ggcttgattt tggttgggtc
    29461 atctcgttct ggtcgcattg attttgaaaa tgctatccaa atgatggaag tcaagaaatt
    29521 tgctaatcgt cttaaaaata tcctttatct agaagaacct gtaagagaaa ttaaagatat
    29581 tcatcgtgtc tttgcaaccg atttaaacac agcctttaaa acagtgttta agtgggaagt
    29641 ataagtactg gaggttaatt gtggagaaaa tcattaaaga aaaaatttct tccttactta
    29701 gtcaagaaga ggaagtcctc agtgttgaac aactgggtgg aatgaccaat caaaactatt
    29761 tggccaaaac aacaaataag caatacattg ttaaattctt tggtaaaggg acagaaaagc
    29821 ttatcaatcg acaagatgaa aagtacaatc ttgaactact aaaggattta ggcttagatg
    29881 taaaaaatta tctttttgat attgaagctg gtatcaaagt aaatgagtat atcgaatctg
    29941 cgattacgct tgattcaacg tcaatcaaga ccaagttcga caaaattact ccaatattac
    30001 aaactattca tacgtctgct aaggaattaa gaggagaatt tgctcctttt gaagaaatca
    30061 aaaaatacga atccttgatt gaagaacaaa ttccttatgc caactatgaa tctgttagaa
    30121 atgcagtctt ctccttagag aaaagactgg ctgacttagg tgttgacaga aaatcttgtc
    30181 atatcgattt ggtgcctgaa aactttatcg aatcacctca aggacgactt tatttgattg
    30241 actgggaata ttcatcaatg aatgatccaa tgtgggattt ggctgccctc tttttagagt
    30301 ctgaattcac ttcccaagag gaagaaactt tcttatctca ctatgagagt gaccaaacac
    30361 cggtttctca tgaaaagatt gctatttata aaattttaca agatactatt tggagtctat
    30421 ggactgtcta taaggaagag caaggtgaag attttggtga ctatggtgtg aatcgttacc
    30481 aaagagctat taaaggtttg gcttcttatg gaggttcaga tgaaaagtaa aaacggagtt
    30541 ccttttggcc ttctctcagg tattttctgg ggcttgggtc taacggttag tgcttatatc
    30601 ttttcgattt ttacagattt gtcacccttt gtggtggctg cagctcatga ttttttgagc
    30661 atctttatct tactagcttt tctcttggta aaagaaggga aagttcgcct ctcaattttc
    30721 ttaaatattc gcaatgtcag tgttatcatc ggagccttgc tagcaggccc tatcggtatg
    30781 caggccaatc tttatgcagt taagtatatc ggaagttctt tagcttcatc tgtatcggct
    30841 atttaccctg cgatttcagt tctattggct tttttctttt tgaagcacaa gatttcgaaa
    30901 aatactgtat ttgggattgt cttgattatt ggagggatta ttgcccagac ctataaggtt
    30961 gaacaggtta attccttcta cattgggatt ctctgtgctt tggtttgtgc tattgcatgg
    31021 ggaagtgaga gtgttcttag ctcctttgct atggaaagtg aactgagtga aatcgaagcc
    31081 ctcttaatcc gtcaagtgac ttcgttcttg tcctatcttg tgattgtgct cttctctcat
    31141 cagtcattta ctgcagtagc caatggacaa ttgctaggtc tcatgattgt ttttgcagcc
    31201 tttgatatga tttcctactt ggcttattat atcgctatca atcgcttgca accagccaag
    31261 gctacaggct tgaacgtgag ctatgtagta tggacggtct tgtttgcagt tgtttttttg
    31321 ggtgcaccgc tagatatgct gaccattatg acgtcacttg tcgtcattgc tggagtttat
    31381 attattatta aagaataaag gagattcgtg tgaaagccat tatcttagca gcgggattgg
    31441 gaactcgctt gcgtcctatg actgaaaata cccctaaagc cttggttcag gttaatcaaa
    31501 aacctttgat tgaataccaa attgagtttc tcaaagaaaa aggaatcaat gacatcatca
    31561 tcattgttgg ttatcttaaa gaacaattcg attacttaaa agaaaaatac ggtgttcgcc
    31621 tcgttttcaa tgataaatac gctgactaca ataactttta ctctctctat cttgtaaaag
    31681 aagaattggc caacagctat gttattgatg ctgacaatta tctctttaaa aatatgttcc
    31741 gcaatgattt gacacgttcg acttatttta gtgtttatcg tgaagattgt accaacgaat
    31801 ggttcttggt ctatggagat gactacaagg ttcaagacat tattgttgat agcaaggcag
    31861 gtcgcatcct tagtggtgta tccttctggg atgctccaac tgcagaaaag attgtcagct
    31921 ttatcgacaa ggcttatgca agtggtgaat ttgttgatct ctattgggac aatatggtta
    31981 aggataatat caaagagcta gatgtctatg ttgaagaatt agaaggcaat agcatttatg
    32041 agatcgatag tgtccaagac tatcgtaaat tagaagaaat tcttaaaaac gaaaattaaa
    32101 gattccaaca tctgacaaaa tagtcggatg ttttttgatt ttttacgaac ttttacgaat
    32161 agatagatga gtagaaaaag aaatggagtt atttatgaaa atcacaaact atgaaatcta
    32221 taagttaaaa aaatcaggtt tgaccaatca acagattttg aaagtgctag aatacggtga
    32281 aaatgttgat caggagcttt tgttgggtga tattgcagat atatcaggtt gccgtaatcc
    32341 agccgttttt atggaacgtt attttcagat agacgatgcg catttgtcga aagagtttca
    32401 aaaatttcca tctttctcta ttttagatga ctgttatcct tgggatttga gtgaaatata
    32461 tgatgcgcct gtacttttat tttacaaggg aaatcttgac ctcctgaaat tcccgaaggt
    32521 agcggtcgtg ggcagtcgtg cttgtagcaa acagggagct aagtcagttg aaaaagtcat
    32581 tcaaggcttg gaaaatgaac tggttattgt cagtggtctg gccaagggca ttgacacagc
    32641 agctcatatg gcagctcttc agaatggcgg aaaaaccatt gcagtgattg gaacaggact
    32701 ggatgtgttt tatcctaaag ccaataaacg cttgcaagac tacatcggca atgatcatct
    32761 ggttctaagt gaatatggac ctggcgaaca acctctgaaa tttcattttc ctgcccgtaa
    32821 tcgcatcatt gctggacttt gtcgtggtgt gattgtagca gaggctaaga tgcgttcagg
    32881 tagtctcatt acgtgtgagc gagcaatgga agaaggacgc gatgtctttg ctattcctgg
    32941 tagcatttta gatggactat cagacggttg ccatcatttg attcaagaag gagcaaaatt
    33001 ggtcaccagt gggcaagatg ttcttgcgga atttgaattt taaaaatgac ctaagctaaa
    33061 attctaagaa aaaatcaatt ttaagagaaa atgaacccaa catttccata ataaaacgca
    33121 tattagcaag tttttaacac ttgataatat gcgttttttc taagtggatt agtagagtag
    33181 aggatttttc tcatataata ctcttcgaaa atctcttcaa actacgtcag cttccatctg
    33241 caacctcaaa acagtatttt gagctgactt cgtcagtctt atctacaacc tcaaagcagt
    33301 gctttgagca acctgtggct agcttcctag tttgcgcttt gattttcatt gagtataagg
    33361 gaaagtatag tgaattgaaa taagatgtga acaactctat caggaaagtc aaattaattt
    33421 atagaaatat tttagcagcc aaggtgtact gttatagatt caatacacta taatttagtg
    33481 taattgagaa aggagaaatg attgtgattg atgttggcta ggttatgttc aatgattcct
    33541 accgtctcaa atcttgtcag taaggaaaaa taaattcttc aaaagtagag attacaaggc
    33601 ttgtttaaga aagaattcaa agaccttgac aaataaaaat aaaatggtta ttataaaaaa
    33661 tggtctaaaa tagatgatga tacttttcga aaatcttttt acgtcagctc agctttgcct
    33721 tgctgtgttt tgagcaagct acggttagct tccgagtttg attttcattt actagaaatg
    33781 aaactgatga gagatatcag tagacatttg agtcaggata ttatggaaaa tgataaaaag
    33841 agctcgtgag attggcatat cagactacta aagtattgag tttgttagga ttttagcgac
    33901 tagttagctg ggaaaggaag atatttgtga caaataataa actgtattcg ttgatagaat
    33961 ttagaaataa aatatatgaa gaattagaac tttccagaag tgatttagcg attttactat
    34021 gtgccatgct tatcgcctct atcggattaa atatggattc gactcccgtg attattggag
    34081 ccatgttaat ctctcctttg atgacaccta ttctgggagt ggggctctct ctagctatat
    34141 ttgattttaa attgttaaga aaatctttta aaatattagc tattcaaatt cttgccagtc
    34201 taatagcttc aacactttat ttttatcttt ctcccatttc gtatgctagt tcggagattg
    34261 ttgctagaac ctctccgact atttgggatg ttctcattgc ttttgtagga gggatagcag
    34321 gtattattgg tgctaggaaa aaagagacca ataatattgt tcctggtgtt gctattgcaa
    34381 ccgccttgat gcctcctctt tgtacagtag gttatgctat tgcttctgct aatctaaaat
    34441 ttatcatagg ctcctcttac ctattcctca tcaattgtag ctttattgtc attgcgactt
    34501 atataggtgt taggttgatg atggttaaga aacattattt taaagataat gaagaagact
    34561 ctaaaatgcg taggattttg cttctagttg ctgttttgct gatgattccg agtttcatct
    34621 ctgcaacgac tttagtgaga gaaacgttga aaaaagagtc ccttaagaaa tttatatcag
    34681 agcagtttca ggggtataat attttgaaaa aaacctattc taaaaagact cataccctaa
    34741 agctaaccat ttcaggaaat tatttgacag aagaagaact cgatatgatt tcaagtaaga
    34801 gaggtgacta tggtttaagt gatgtttctg ttcaagtttc acaattgtct gattcagaac
    34861 aacttagtaa ggaagagctg gtggagtatt tcttccagta tatcaaggat aaggaagcaa
    34921 aagaaaagga gaaagccaat aaatttgata cagagtctga ggagcaataa tttcttgaga
    34981 atagctggtt tctctcgtga gtcttctatg tatatcaaag gaagactgag gttttaagta
    35041 taaaactttt cttctattat agtagctaag tcttgacagg gttcaaaaaa tggtttacac
    35101 tttataaagt ttattacttt gaaaaggtgt gatactgtgg ctacggcaac aaaaaagaaa
    35161 aaatcaacag ttaaaaaaaa tctagtcatc gtggagtcgc ctgctaaggc caagacgatt
    35221 gaaaaatatc taggcagaaa ctacaaggtt ttagccagtg tcgggcatat ccgtgatttg
    35281 aagaaatcca gtatgtccgt cgatattgaa aataattatg aaccgcaata tatcaatatc
    35341 cgaggaaaag gccctcttat caatgacttg aaaaaagaag ctaaaaaagc taataaagtt
    35401 tttctcgcga gtgacccgga ccgtgaagga gaagcgattt cttggcattt ggcccatatt
    35461 ctcaacttgg atgaaaatga tgccaaccgt gtggtcttca atgaaatcac caaggatgca
    35521 gtcaaaaatg cttttaaaga acctcgtaag atcgatatgg acttggtcga tgcccaacaa
    35581 gctcgtcgga tcttggatcg cttggtaggg tattcgattt cgcctatttt gtggaagaag
    35641 gtcaagaagg gcttgtcagc aggtcgcgtt cagtccattg cccttaaact catcattgac
    35701 cgtgaaaatg aaatcaatgc cttccagcca gaagaatact ggacagttga tgctgtcttt
    35761 aaaaagggaa ccaaacaatt tcatgcttcc ttctatggag tagatggtaa aaagatgaaa
    35821 ctgaccagca atgacgaagt caaggaagtc ttgtctcgtc tgactagtaa agacttttca
    35881 gtagatcagg tggataagaa agagcgcaag cgcaatgctc ctttacccta taccacttca
    35941 tctatgcaga tggatgctgc caataaaatc aatttccgta ctcgaaaaac catgatggtt
    36001 gcccaacagc tctatgaagg aattaatatt ggttctggtg ttcaaggttt gattacctat
    36061 atgcgtaccg attcgactcg tatcagtcct gtagcgcaaa atgaggcggc aagcttcatt
    36121 acggatcgtt ttggtagcaa gtattctaag cacggtagca aggtcaaaaa cgcatcaggt
    36181 gctcaggatg cccatgaggc tattcgtccg tcaagtgtct ttaatacacc agaaagcatc
    36241 gctaagtatc tggacaagga tcagctcaag ctatataccc ttatctggaa tcgttttgtg
    36301 gctagccaga tgacagcggc cgtttttgat accatggctg ttaaattgtc tcaaaatgga
    36361 gttcaatttg ctgccaatgg tagtcaggtt aagtttgatg gttatcttgc catttataat
    36421 gattctgaca agaataagat gttaccggac atggttgttg gagatgtggt caaacaggtc
    36481 aatagcaaac cagagcaaca tttcacccaa ccgcctgccc gttattctga agcaacactg
    36541 attaaaacct tagaggaaaa tggggttgga cgtccatcaa cctacgcgcc aaccattgaa
    36601 accattcaga aacgttatta tgttcgcctg gcagccaaac gttttgaacc gacagagttg
    36661 ggagaaattg tcaataagct catcgttgaa tatttcccag atatcgtaaa cgtgaccttc
    36721 acagctgaaa tggaaggtaa actggatgat gtcgaagttg gaaaagagca gtggcgacgg
    36781 gtcattgatg ccttttacaa accattctct aaagaagttg ccaaggctga agaagaaatg
    36841 gaaaaaatcc agattaagga tgaaccagct ggatttgact gtgaagtgtg tggcagtcca
    36901 atggtcatta aacttggtcg ttttggtaaa ttctacgctt gtagcaattt cccagattgc
    36961 cgtcataccc aagcaatcgt gaaagagatt ggtgttgagt gtccaagctg tcatcaggga
    37021 caaattattg agcgaaaaac caagcgtaat cgcctattct atggttgcaa tcgctatcca
    37081 gaatgtgaat ttacctcttg ggacaagcct gttggtcgtg actgtccaaa atgtggcaac
    37141 ttcctcatgg agaaaaaagt ccgtggtggt ggcaagcagg ttgtttgtag caaaggcgac
    37201 tacgaggaag aaaagattaa ataagaggag gggcccgaaa gtaaatttca ggctcctttt
    37261 ggttagaact tgacaaaata catcatttta tgcgaaacta gaagaagatt attttaacta
    37321 ggagaagtta tgcgtcttat ctatctgata attggttttt tatcactggg cttggctatt
    37381 gttggggttg ttttaccctt gttgccgaca acgcctttcc ttttgttgtc tattgcttgt
    37441 ttctccagaa gttccaagcg tttcgaagac tggctttatc ataccaagct ctatcaaaca
    37501 tatgtagctg attttcgcga gactaagtct attacgcgtg aacgaaagaa aaaaatcatc
    37561 gtctctatct acgtcttgat gggaatttct atttattttg cacctctttt accagtcaaa
    37621 atcggtctgg gtgctttgac catctttatc acttattatc tcttcaaggt cattccagac
    37681 aaagaatagt taaaacagta gttatttgcc ttgataaaat tgaaagcata ttcataacaa
    37741 tatgatataa taaatttgaa gtaatattca aggagaatca aatgatttac gaattttgtg
    37801 ctgaaaatat gactttactt gaaaaagcga tgcaggctgg agctcgtcgg attgaactct
    37861 gtgataatct agcagttggt gggacaacac ccagctatgg agtgactaag gcagcggttg
    37921 aactggcagc taactacgat acaaccatca tgaccatgat tcggccacgt ggtggtgact
    37981 ttgtctataa tgacctagaa attgctatca tgctagaaga cattcgtttg actgctcagg
    38041 ctggaagtca aggggttgta tttggagctt taactgctga taaaaagttg gataagccta
    38101 atctggaaaa gttaattgct gcatcaaaag gaatggaaat tgtctttcac atggcctttg
    38161 atgaactaag tgatgaagat caaccggaag ctattgactg gctcagtcaa gccggtgtca
    38221 ctcgtatcct aactcgtgct ggtgtgtctg gcgactcctt agaaaaacgt tttgttcact
    38281 atcacagaat tttggagtac gctaaaggta aaattgaaat tctaccaggt ggggggattg
    38341 accttgaaaa ccgtcaaacc tttatcgacc aggtgggggt aacacaattg catggtacta
    38401 aggttgtttt ttaaaaaata gaaaggaact gctagctttt ggtagcagtt ttcacttatg
    38461 tttgaaattt ttaaatccta tcaatttaat caagaaaagg ctcatgatta tggttttata
    38521 gaaaatagcg aagtctggac atatagttgc cagattttgc aaggtgactt tgtcatgact
    38581 gtgtccatca ctgctgataa tgtgaacttt caagtctttg accaagagac tggtgacctc
    38641 tatcctcacg ttcatatgga aagcatgagg ggaagttttg tcggaaatgt ccgtgaggct
    38701 tgtctggaga ttctttacca gattcggaag gcttgttttg atgtgcaaga ttttatctgt
    38761 catcagacta agcgtatcat gactcaagtt caggaaaagt atggaaacca gttggagtat
    38821 ctgtgggaaa aatcgcctga tacagctgta ttgcgccatg aaggcaatca aaagtggtat
    38881 gccgtcttga tgaaaatctc ttggaataag ctggaaaagg gcagagaagg acaagtggaa
    38941 gcagtcaacc tcaagcatga ccaagtagct aatttgcttt cacaaaaggg gatttatcca
    39001 gccttccata tgagcaagcg ctactggatt agtgtgtccc ttgatgatac tttatcagat
    39061 gaagaagtac tggaattgat agaaaaaagt tggaacttaa cctctaaaaa atgaaatatt
    39121 ttaataattt tcatgaactt tcaattagct aaatattctt tactgaagaa attttcagaa
    39181 aatatagaat ttaccacacc agaggaatat ggtgccatct tcaaatacct gattgagaat
    39241 gtcaagacgg atcgtcagat catctattcg cctcactgtc atgatgacct tggaatggca
    39301 gtggcaaata gccttgctgc tgtcaagaat ggtgcaggac gtgttgaagg gactatcaat
    39361 ggtattaggg agcgagctgg aaatgctgct ttggaagaaa ttgcagtggc tctcaatatt
    39421 cgccaagatt actaccaagt agaaaccagt attgtcctaa atgagaccat caatacgtca
    39481 gaaatggttt ctcgcttctc tggtattcca gttcctaaaa acaaagccgt cgttggtggc
    39541 aataccttct cccacgaatc tggtattcac taagatggag tccttaaaaa tcctctcact
    39601 tatgagatca tcacacctga attggttggt gttaagattc cgcttggaaa attatctggt
    39661 cgccatgctt ttgttgagaa actgagagaa ttggccctag attttacaga agaggatatc
    39721 aaatcactct ttgctaagtt caaggcactg gccgataaga agtaagaaat cacagatgca
    39781 gatattcgag ctttggtagc tggaaccatg gttgaaaatc cagaaggctt ccactttgat
    39841 gatttacaac ttcaaactca tgcagataat gacattgaag cgctcgttag cctagccaat
    39901 atggatggtg agaaagtcga atttaatgcg acagggcaag gttccgttga agcaatcttt
    39961 aacgctatcg ataagttctt taaccaatct gttcgtttgg tgtcctacac tatcgatgca
    40021 gtaacagatg gaatcgatgc ccaggatcgg gttttggtca ctgttgaaaa cagagataca
    40081 gaaaccatct ttaatgcagc agggcttgat tttgatgtgt tgaaggcttc tgctattgcc
    40141 tatataaacg ctaatacctt tgttcaaaaa gagaatgcag gtgagatggg atgcagtgtt
    40201 tcttaccatg atatgcctag tgtgtaaagg agaaggctat ggcaaagaaa atagtagctc
    40261 tagcaggaga cggaattggc ccagaaatca tggaggttgg tttagaagtt ctggaggctc
    40321 tagctgaaaa aacaggtttt gactatgaga ttgacagacg accgttcgga ggtgcagata
    40381 ttgatgcagc atggcctccc ttacctgatg aaacccttaa ggcaagtagg gaagcagatg
    40441 ctatcctact agcagctatc ggtagtcctc agtatgatgg agcagtggtt cgccctgaac
    40501 aaggcctgat ggctctccgt aaggaactca atctttacgc taatattcgt cctgtaaaaa
    40561 tctttgacag tctcaagcat ttgtcaccac tcaaactgga acgaattgct ggtgtagact
    40621 ttgtcgtggt gcgtgaattg acaggcggga tttactttgg agatcatatt cttgaagagc
    40681 gcaatgcgcg tgatatcaac gactatagct atgaggaagt ggagcggatt attcgcaaag
    40741 cctttgaaat tgcaagaaat cgcagaaaaa tccttactag tatcgataag caaaatgttc
    40801 tagcgacctc aaaactctgg cggaaagtag ctgaggaagt cgcacaggat ttcccagatg
    40861 taaccttgga acaccagctg gtagactcag ctgctatgct tatgattacc aatcctgcta
    40921 agtttgatgt tattgtaacg gagaatcttt ttggagatat tttatctgat gaatcaagcg
    40981 tcttatctgg tacacttggg gttatgccat cagccagtca ttccgaaaat ggaccaagtc
    41041 tctatgaacc tattcacggt tcagcacctg atattgcagg tcaaggaatt gccaatccta
    41101 tttccatgat tttatcagtt tccatgatgt tgagagatag tttcggacgt tatgaggatg
    41161 cagagcgtat caaacgtgct gttgagacaa gtctggcggc aggaatttta acgagagata
    41221 taggaggtca ggcttcaaca aaggaaatga cggaagctat tattgcaagg ttatgaagtt
    41281 agacgaaaaa attactctag tccttttgat ttggaatgtc atcattttct tgatttatgg
    41341 cattgacaaa ttcaaggcaa gaagaagagc ttggcgcatc caagagaaaa tcttactcat
    41401 tttagccctt acttgtggtg gttttggggc ctggttagct ggaatcactt ttcaccacaa
    41461 gactcgaaaa tggtacttta aaacagtttg gtttcttggg atggtgacca cactagtagc
    41521 cttatatttt atttggaggt aatggatggc agggtcttcg agggaacacg ctgcttgggc
    41581 tctagcggac tatggtttta aggtcgtgat tgcaggatct ttcggtgaca ttcattacaa
    41641 taatgaactc aataatggcc tgttgccaat cgttcagcct agagaggtta gagagaaact
    41701 agcccagcta aaaccaaccg accaggtaac tgtggacttg gaacaacaaa aaatcatctc
    41761 accagttgaa gaattcacct tcgagataga tagcgagtgg aaacataaac tcctaaatag
    41821 tttggatgat atcggtatta ccttgcagta tgaagagttg attgctgctt atgaaaaaca
    41881 acgaccagcc tactggcagg attagaaaaa atagaaaagg aaatatagta aactgaaata
    41941 agatgtaaac aaatgaatta gagcttaaca tccatttcca gcaatttttt agaaactaca
    42001 gtggactatt ctggattcaa cacattataa aattatgaca aaacacattc acaagaaggc
    42061 tacgacattt taaaaggtga gggcggatgt atcgtttgcc ctactaaagt tggttacatt
    42121 atcatgacca gcaacaaggc aggacttgag cgtaagttcg cagccaaaga acgtaagcgt
    42181 aacaaaccag gtgttgttct ctgcggtagc atggatgaac ttcgcgcttt agcgcaactc
    42241 aacccagaaa ttgaagcatt ctactaaaaa cattggatga agatattctt cttggttgta
    42301 tccttccttg gaaaccagaa gcctttgaaa aactcaaagc atacggggat ggccgtgaag
    42361 aacttatgac tgatgtacgt ggtactagct gttttgttat caagtttgga aaagcaggtg
    42421 aacaattggc tgccaagctt tgggaagaag gtaaaatggt ctacgcctca tatgcttcaa
    42481 tgacaaaacg attgaaactc gctatgagag caaggtgtaa tggtgtctat ggtcgataag
    42541 gacggcaaac tcatcccaga acaaggagga gcacgttcaa cttcaccagc accagttgtg
    42601 atccgtaaag ggcttgacat tgataaaatc atgatgcacc tgtcagatac ttttaactca
    42661 tgggactacc gtcaggttga gtattattaa gataaaaaaa gaagtctagt gttatgagat
    42721 attaaagctc ctaacactgg actttttgtt tagaatttct tttctttttc tataggatat
    42781 ggtattctat gtagaaaata tatgttaata agtaatgcca atatttaaac atcattagta
    42841 aaaggagtta gattgatgaa taaaagaaaa gttagtttag aagattttta taaatggtat
    42901 agtctaaata aagaagagtt attaaataag gcaactgttg gtgaaaagtt taatgataaa
    42961 ttaaaagaag agtttctcca ggaatggcct ttggatagga ttttaacaat gtcaatcgat
    43021 gaatatgtaa taggaaaggg acagcaaaat aagtctttat gctacgctct tgagaaggga
    43081 aaatacaaaa atctatttct tggaatttct ggtggctcag cttcaaaatt tggtatttat
    43141 tggaataaaa aaacaaacaa atataaagat caagctaata atgagatttc agagttggat
    43201 cagcgatttt caaaattaaa atcagatttg tatgaaatta tcaaagaagg tattcgtttt
    43261 aactttgaaa atcctatttt tgatatgaaa agatcaacaa atgaatttat tggtcgttct
    43321 gctatggtga caaaattact ttgtatctat actgagggag atcctttctt tggtgtaaat
    43381 attaatagtc agaaagaatt ttggaaccac tttgtttctc agacaaatca aggtggacct
    43441 tatctgcaaa atcataaaat aattgaacta gtgtccaaaa cttatcctga gttggagcca
    43501 tcgaaattag gaactatgct ttttgagtat tctaagcttt ttatggaaaa taaggaagac
    43561 aatagtacaa tggattcatc aaacaatttt cgtcatcaat taactcaatc tctattaaag
    43621 tctccaaacc ttatccttcg tggtgctcct ggcacaggaa agacttatct tgctaaagaa
    43681 attgccaaag aattaacgga tggcaacgaa gaccaaatcg gatttgtaca atttcaccca
    43741 tcctatgatt atacggattt tgtagaaggt ttaagaccag tatcaaatgg ggatggagct
    43801 attgagttta ggctacagga cggtattttt aaagattttt gtcagaaagc aaaagaaacc
    43861 caattgattg gaggacaaga taattttgat gaggcttggg attcttactt agaatatata
    43921 aatgttgctg aagaaaaaga atatataaca aaaacatctt acttatctgt taatagtaga
    43981 caaaatttgt cagtaaatta tgatagtggt gttccaggat ggtcactacc tagcaaatat
    44041 gtttacgagt tgtataaaga taaaaattat aataagcaag aatactacaa aagtggtgga
    44101 aaaactgtcc tagaaacatt gagaaagaga tttggtttga aagactatgt ttccccaaca
    44161 gaaattgata ctgataagaa attcgtcttc atcatcgatg agatcaatcg tggggagatt
    44221 tctaagattt ttggcgaact ctttttttct atcgaccctg gctatcgtgg tgaaaaagga
    44281 agtgtttcta cccaatatgc aaatctacac gaaactgatg aaaagttcta tatccccgaa
    44341 aatgtttaca tcatcggaac tatgaatgat attgatcgtt cagtggatac ctttgatttt
    44401 gctatgcgtc gtcgttttcg ttttgttgaa gttactgccg agggtcaagt tggcatgttg
    44461 gataaagagt tgaatatcca tgcagaagaa gcaaaaattc gtctaagaaa cttgaacgct
    44521 gctatcgaaa atgttcagga attaaacagt cattatcata ttggaccaag ttattttctt
    44581 aagttgaagg atgtagattt tgactatgaa ttactctggt ctgattatat taagcctctc
    44641 ctagaagact acttgcgagg ttcttatgat gaggttgaaa ctttggaaac tttgaaaaaa
    44701 gcatttgaac tgacaaataa tgagcaaaaa gatcagacag tagctgatga caatgaaggt
    44761 gatgaaaacg atgatgcgga ttactgataa tcaacacaag attattaaag aaaaatttgt
    44821 tgaagaatat cctaaactaa gcaatcttct tttagacaga accttggaaa gtctatccca
    44881 agatgaacgt attttcattt ttccaaatga tttgactcat actcctgatt tggataagga
    44941 ccaaaagatt tttgaaacag tcaatcagaa aatcaagaca gggaacgtga ttggttttct
    45001 tggatatggt caggaaagat taacgatttc ctcacgattt tctgatgaga gtaatgacca
    45061 ttttttgcat tatctcttaa acaaggttct tcatatcaat ctcactagtt tagatgttgc
    45121 tttgtctcgt gaagagaggc tttatcaact tttgatgtat ctcttcccca agtatctaca
    45181 agctgctatt cgaaaaggtc tttataagga atatcatcga ttttctcata acgacagtca
    45241 tgttaaggga gtgattgatg taagaagcca tctcaagaaa aatcttcctt tcacgggaaa
    45301 tattgcctac gcaacgagag agttcaccta tgataatccc ctcatgcagt tggtccgtca
    45361 cactattgaa tacattaaga atcagaaaag cattggtcaa ggggtactag ataatctctc
    45421 aactagtcgt gaaaacgtat ctgaaatcgt gcgtgtaacg ccctcttata aactagctga
    45481 tcgtgctaag attactcgga gaaatcaatc taaacctata cgtcatgcat actttcacga
    45541 gtacagaaac ttacaagaac tttgtctgat gatcctaaac caagaaaagc acggtttagg
    45601 gtatcaagat caaaaaatct atggtattct ctttgatgtt gcctggcttt gggaagagta
    45661 tgtttacacc ttgttgccaa aaggttttgt acatcccaga aataaggata agacggatgg
    45721 aatttcagta ttttctgttg ggaaacgaaa agtatatcca gatttttatg acagagaacg
    45781 aaagattgtt ctagatgcaa aatataaaaa actggaattg actgaaaaag gaatcaaccg
    45841 tgaggactta ttccagctga tttcctattc ttatatttta aaagctgaga aggctggact
    45901 tgtttttccg agcaaggaca aggtcattga taatgagata ggaaacctag caggttatgg
    45961 agctttgttg aagaaatggt ctatccaaat tcctcagaag tcttcatctt atagtgcatt
    46021 ttgtaaaatg atggaaaatt cagaagaaaa ttttaaagcg attattgatg aagaagtggg
    46081 gagaaaataa tttcccctct ttcttttatt tttaacacaa gcaaaatccg aacaatatat
    46141 tttaattcat aaaataattt gacaaaaact gtactttggt ttataataaa ttaaggaaac
    46201 gtcggaaaag gcgtagtgat gcgagagcat aggtaggtca ttacaaaaga aacgagacat
    46261 cgatatgtta aatgaatttc caatttttga ttacgaagat attcaattga ttccaaataa
    46321 atgtgtcatt aaaagccgtg cagaagcgga tacaagtgtc actttaggaa atcacacctt
    46381 taaactacct gttgtgccag cgaatatgca gacgattttg gatgaaaatg tagcagagca
    46441 actggctaaa ggtggttact tctacattat gcaccgtttt gatgaggcag gacgcattcc
    46501 ttttattaaa cgaatgcaca atcaagggct cattgcttcc atatctgtcg gtgttaagga
    46561 ctatgagtat gatttcgtta gacagctcaa gactgatgct cctgagtata tcactattga
    46621 tattgctcat ggtcatgcgg atagcgtgat ttctatgatt caacacatca agaaagaatt
    46681 gccagatacc tttgtcattg ctggaaatgt gggaacacca gaagctgtgc gtgaattgga
    46741 aaatgctggt gcggatgcta ctaaggtcgg aatcggtcct ggtaaggttt gtatcaccaa
    46801 ggttaagact ggttttggta caggtggttg gcagttggct gctctacgct ggtgtgccaa
    46861 ggctgcgcgt aaaccgatta tcgctgatgg aggaattcgt actcacggtg atattgccaa
    46921 gtctatccgc ttcggtgcta gcatgatcat gattggttcc ctctttgcag gacatattga
    46981 aagtccaggg aaaacgattg aagtcgatgg tgaacagttc aaagaatatt atggttcagc
    47041 ctcacaatat caaaaaggtg cttacaaaaa tgtggaaggc aaacgtatct tgcttcctgc
    47101 taaaggtcat ctgcaagaca ctttaactga gatggaacaa gaccttcaaa gtgctatttc
    47161 ttatgcaggt ggacgtcagg ttgctgacct taaacacgtt gattatgtga tcgtgaaaaa
    47221 ctccatctgg aatggggatg cttcccacta agacggggtc tttgactaaa aaacttgtta
    47281 ttagagcaaa tttctgttat aataaaacaa gtttccaccc ttagtgtaat ggatatcacg
    47341 taagattccg gttcttgaga tgggggttcg attccctcag ggtggatgta aacattctaa
    47401 aaagccttta atagggcttt tttctttaca ctactctaaa tttgccacta aaactgagaa
    47461 tctctgtcta aagaattccc aaatgctttc cagtcccgtt ttagagtgac tcagggggct
    47521 ttttttgata taataaaaag gactgttatc agttagaaag aggttggtat gaaagaatta
    47581 caaactgtac taaagaacca ttttgcaatc gaatttacag acaaaaagtt actggaaact
    47641 gcctttactc atacgagtta tgccaatgag caccgcctct taaaaatttc acataatgaa
    47701 cgcttggaat ttttaggaga cgctgttcta cagttattga tttcagaata tctgtataaa
    47761 aaatatccta aaaagcctga aggtgaccta tcaaaactcc gtgctatgat tgtccgtgag
    47821 gagagtttag ctggttttgc gcgtgattgc cagtttgacc agtttatcaa gttgggtaaa
    47881 ggggaagaaa aatctggtgg tcgcaatcgt gacaccattc ttggtgatgc ctttgaagcc
    47941 tttcttggtg cccttctttt ggataaggat gtggccaagg tcaaggaatt tatctatcaa
    48001 gtcatgattc ctaaggttga agcaggcgaa tttgagatga ttacagacta taaaacccat
    48061 ctccaagagt tacttcaggt caatggtgat gtggctattc gttatcaggt gatttctgaa
    48121 acagggcctg ctcacgataa ggtctttgat gtagaagttc ttgttgaagg taagagcatc
    48181 ggtcaaggcc aaggtcgttc taagaaatta gcagagcagg aagctgccaa aaatgccgtt
    48241 gagaaggggc tggattcatg tatttaaagg aaatcgaaat tcaggggttc aagtcttttg
    48301 ctgataagac caaggtcgtt tttgaccaag gtgtgacggc agttgttgga cccaatggat
    48361 ctggaaagtc caatattaca gaaagtctgc gttgggcttt gggggagtct agtgtcaaga
    48421 gtctccgtgg gggcaagatg ccggatgtca tctttgctgg aacagaaagt cgcaaaccgc
    48481 tcaattatgc ttctgtagtt gtgactctgg ataatcatga cggatttatc aaggatgcag
    48541 gtcaagaaat cagggtggaa cgccatatct atcgtagtgg agatagcgaa tacaagattg
    48601 acggcaagaa agtccgtctg cgtgatattc atgacctttt cttggataca ggtttgggac
    48661 gagattcctt ctctattatt tcccaaggga aggttgagga gatttttaat tccaagcctg
    48721 aggagcgacg agctattttt gaagaagctg ctggagtttt aaaatacaag actcgcagaa
    48781 aagaaaccga gagtaaactg cagcaaactc aggataatct ggaccgctta gaggacatta
    48841 tctacgagtt ggataatcaa atcaagcctc ttgagaagca agctgaaaat gcccgtaaat
    48901 ttctagactt agaaggtcaa cgcaaggcta tttacttgga tgtattggtt gctcaaatca
    48961 aggaaaataa ggcagaacta gagtcgacag aagaagagtt ggctcaggtt caagaactct
    49021 tgatgagtta ttaccaaaag cgtgaaaaat tagaagaaga aaatcaaact cttaaaaagc
    49081 aacgccaaga tttacaggct gaaatggcca aagaccaagg cagtttgatg gacttgacta
    49141 gtctgattag tgatttagaa agaaaattag ccctatcgaa actggagtcc gagcaagtgg
    49201 ccttgaatca acaggaggca caagctcgtt tggctgcttt ggaggataag agaaattcac
    49261 tcagcaaaga aaagtctgat aaagaaagct ctttagctct gttagaggga aatctagtcc
    49321 aaaataatca aaaactcaat cgtttagaag ctgaattgct ggctttctca gacgatcctg
    49381 atcagatgat tgagctctta cgtgaacgct ttgtagctct tttacaagaa gaagcggatg
    49441 tctcaaacca gttgacccgt attgagaatg agttggaaaa tagtcgtcag ctttctcaaa
    49501 aacaagcaga tcaactagaa aagctgaaag agcaattagc tatagctaaa gagaaggcta
    49561 gtcagcaaaa ggaagagctt gaaactgcca aggagcaggt tcagaaatta ttggctgact
    49621 accaagctat tgccaaggag caagaggagc agaaaacttc ctatcaagct caacaaagcc
    49681 aactctttga ccgtctggat aatctcaaaa acaagcaggc cagagctcaa agtttggaaa
    49741 atatcctgag aaatcatagt aacttttatg caggtgttaa gagtgttctc caagaaaaag
    49801 atcgcctagg tgggattatt ggtgcagtca gtgagcatct gacctttgat atgcattatc
    49861 aaactgccct agacattgcg cttggagcga gtagtcagca cattattgta gaagatgaga
    49921 atgcggcaac caaagccatt gatttcctca aacgaaacag agccggtcgt gcaacctttc
    49981 ttcctttgac cactattaag gcgcgtacga tttctagtca gaaccaagat gctatcgctg
    50041 taagcccagg tttccttggg atggcagatg agttggtgac ttttgatact agactggaag
    50101 ccattttcaa gaacttgcta gctacgacgg ctatctttga taccgtagaa catgcgcgtg
    50161 cagcagctcg ccaagttcgt tatcaggttc gtatggtgac attggatggg acagaattac
    50221 gcacgggtgg ttcctatgcg ggtggtgcca atcgccaaaa taacagtatt ttcatcaagc
    50281 cagaactgga gcaattacaa aaagaaattg ctgcagatga agcaagcttg cgttcagaag
    50341 aagtggcttt gaagaccttg caagatgaga tggccagatt gaccgagtca ttagaagcca
    50401 tcaaatctca aggagagcag gcacgtattc aggagcaagg cttgttcctc gcttatcagc
    50461 aaactagtca gcaagttgaa gaactggaaa ctctttggaa actccaagaa gaggaaaaag
    50521 atcgtctttc cgagggagat tggcaagcag acaaggaaaa ctgccaagag cgtcttgctg
    50581 caatcgccag tgacaagcaa aatctggaag ctgagattga agagattaag tctaacaaaa
    50641 atgccatcca agaacgctat caaaacttgc aggaagagct agcgcaagct cgtttgctta
    50701 agacagaact gcaagggcaa aaacgttatg aagtgactga tattgaacgc ttaggtaagg
    50761 aactagataa tcttgatatt gagcaagaag aaattcagcg ccttcttcaa gaaaaggttg
    50821 acaatcttga gaaagttgat acggatttgc tcagtcaaca ggctgatgaa gccaaaactc
    50881 aaaaaacaaa tctccaacaa ggtttgattc gcaagcagtt tgagttggat gatattgagg
    50941 gtcaactgga tgatattgct agtcatttgg atcaggctcg ccagcagaat gaagagtgga
    51001 ttcgcaagca aactcgtgct gaagcaaaga aagaaaaggt tagcgagcgc ttgcgccatc
    51061 tacaaagtca attaacagac cagtaccaga tcagctacac agaagcttta gaaaaggcgc
    51121 atgagttgga aaatctcaat ctggcagagc aagaagttaa ggatttagag aaggctatac
    51181 gctcactggg tcctgtcaat atagaagcta ttgaccagta cgaagaagtt cacaaccgtc
    51241 tggatttcct aaatagccaa cgtgatgata ttttgtctgc gaaaaacctg cttcttgaaa
    51301 ccatcacaga gatgaatgat gaggtcaagg aacgctttaa atcaaccttt gaggccattc
    51361 gtgagtcctt taaagtgacc ttcaagcaga tgtttggtgg aggtcaggct gacctcattt
    51421 tgactgaagg agacttgctg acagctgggg ttgaaatttc tgtccaacca ccaggcaaga
    51481 aaatccagtc tcttaatctc atgagtggtg gtgaaaaagc cctatcggct cttgccttgc
    51541 tcttctctat cattcgagtt aagactatcc cgtttgttat cttggatgag gtagaggctg
    51601 cgctagacga agccaatgtt aaacgtttcg gggattatct caaccgcttt gataaggaca
    51661 gtcaatttat tgtcgtaacc caccgtaagg ggaccatggc agcggccgat tctatctatg
    51721 gagtgaccat gcaagaatcg ggtgtttcaa agattgtttc agttaagtta aaagatttag
    51781 aaagtattga aggatgacaa ttaaactagt agcaacggat atggacggaa ccttcctaga
    51841 tgggaatgga cgctttgata tggatcgtct caagtctctc ttggtttcct acaaggaaaa
    51901 agggatttac tttgcggtgg cttcgggtcg gggatttctg tctctaggaa aattatttgc
    51961 tggtgttcgt gatgacatta ttttcatcgc ggaaaatggc agtttggtag agtatcaagg
    52021 tcaggacttg tatgaagcga ctatgtctcg tgacttttat ctggcaactt ttgaaaagct
    52081 gaaaacgtca ccttatgtag atatcaataa actgctcttg acgggtaaga aggggtcata
    52141 tgttctagat acggttgatg agacctattt gaaagtgagt cagcattata atgaaaatat
    52201 ccaaaaagta gcgagtttgg aagatatcac agatgacatt ttcaaattta caaccaactt
    52261 cacagaagaa acgttagaag ctggtgaagc ttgggtcaat gataatgtcc ctggtgtcaa
    52321 ggctatgaca actggctttg aatctattga tattgttctg gactatgtcg ataagggtgt
    52381 agctattgtt gaattagcta aaaaacttgg tatcacaatg gatcaggtca tggcttttgg
    52441 agacaatctt aatgacttac atatgatgca ggttgtggga catcctgtag ctcctgaaaa
    52501 tgcacgacct gaaattttag aattagcaaa gactgtgatt ggtcaccata aggaacggtc
    52561 ggttatagct tatatggagg gcttataatg gcagatataa aattgattgc attggacttg
    52621 gacgggacct tgctgactac tgataaaagg ctgacggatc gtaccaagga aaccttgaaa
    52681 gctgcgcgtg atcgtggtat caaggtcgta ttgacaactg gtcgtccctt aaaagccatg
    52741 gatttctttc tccatgagtt agggactgac ggtcaggaag atgagtatac cattactttt
    52801 aatggtggat tagttcagaa aaatacagga gaaatccttg ataaaacagt cttttcatat
    52861 gatgatgtgg cacgtttgta tgaagaaaca gagaaattat cactgcctct tgatgccatc
    52921 tcagaaggaa cagtttatca aatccaatcg gaccaagaaa gtctttatgc caaattcaat
    52981 ccagccttga cctttgttcc agtggacttt gaagacttat ctagtcaaat gacctacaac
    53041 aaatgcgtga ctgcctttgc tcaagaaccc ttggatgcag ccattcagaa gatttctcca
    53101 gaattgtttg accaatatga aatctttaaa tcacgtgaaa tgttgctaga gtggtcacca
    53161 aagaatgttc ataaagcaac aggtttggca aaactaatta gccatcttgg aatcaaccaa
    53221 agccaagtta tggcctgtgg tgacgaggcc aatgacctct ctatgattga atgggcaggg
    53281 ctcggtgttg ccatgcaaaa cgctgttcct gaagtcaagg cagtcgcaaa tgtggtaact
    53341 cctatgacca acgatgagga agctgtcgcc tgggctatcg aagaatatgt gctaaaggag
    53401 aactaagata tgggattgtt tgaccgtcta ttcggaaaaa aagaagaacc taaaatcgaa
    53461 gaagttgtaa aagaagctct ggaaaatctt gatttgtctg aagatgttga tcctaccttc
    53521 acagaagttg atgaagttcc tcaggaagaa gcagaggttg aaattgttga acaagctgtg
    53581 ttccaagaag aggaaatcca agacacagtt gaagaaagtc tggattcaga gccagttgta
    53641 ggggtttctc aagaagaagt cgaagaattt ccacactcag aagaattacc agaggaagag
    53701 aagcttgatc acgaaggaac tatagaagaa aataattctg aagttcttga agcagaaagg
    53761 cctcaagcag aagaaaccgt tcaggaaaaa tatgaccgca gtcttaagaa aactcgcaca
    53821 ggtttcggtg cccgcttgaa tgccttcttt gctaacttcc gctctgttga cgaagaattt
    53881 ttcgaggaac tggaagaact gctgattatg agtgatgttg gtgtccaagt cgcttctaac
    53941 ttaacggagg aactacgtta cgaagccaag cttgaaaatg ccaagaaacc tgatgcactt
    54001 cgtcgtgtca tcattgagaa attggttgag ctttatgaaa aggatggtag ctacgatgaa
    54061 agcatccact tccaagataa cttgacagtt atgctctttg ttggtgtgaa tggtgttggg
    54121 aaaacaactt ctatcggaaa actagcccac cgctacaaac gagctggtaa gaaggtcatg
    54181 ctggttgcag cagatacctt ccgtgcgggt gcagtagctc agctagctga atggggccga
    54241 cgagtagatg ttccagtagt aactggacct gaaaaagctg atccagccag cgtggtcttt
    54301 gatggtatgg aacgtgccgt ggctgaaggt atcgatattc tcatgattga tactgctggt
    54361 cgtctgcaaa ataaggataa ccttatggct gagttggaaa agattggtcg tattatcaaa
    54421 cgtgttgtgc tagaagcacc acatgaaacc ttcttggcac ttgatgcatc aacaggtcaa
    54481 aatgccctag tacaggccaa agaattttcg aaaatcacac ctttaaccgg aattgttttg
    54541 actaagattg atggaactgc tcgaggaggt gtggttctag ccattcgtga agaactcaat
    54601 attcctgtaa aattgattgg ttttggtgaa aaaatcgatg atattggaga gtttaactca
    54661 gaaaacttta tgaaaggtct cttggaaggt ttaatctaat cagaagcaaa aatcctgcaa
    54721 ggcataaact tgcaggaaat ttttttattc taagcgacca tcttgacgat aggcgatatc
    54781 tggttgccaa gtccatttgg caccgaattt ttcaagtagg tcaaagctgg cttgaggtcc
    54841 catgcttcca gctttatagt catgaagtgg ggcaccattt tcagcccaga gcttttcaat
    54901 acggtcaatt aacttccatg acgcaccaac ttcatcccag tggctaaagt tagttgagtt
    54961 gttatttagg acatcataaa tcaatttttc gtatggttct ggagaagcac cagttgcagt
    55021 cgcagctgta cggtaatcaa gtgagttagg agccaagtta aattcttctc ctacttgctt
    55081 cccatttagg ctaagagaga agccttctgt tggttgaata tagatggtca aaatatttgg
    55141 agcaagtggt tctccaaata tagaatccat ttgtttaaag acgatgttga catgagttcc
    55201 tttttcagtc agtcgtttac ctgtacggaa aaagaaagga acactacgga atcgatcgct
    55261 gtctacaaag aaggcaccag atgtaaaggt ttcagttgtt gattctggat tcacatttgg
    55321 ctcgctacga taagagatgt atttcatgcc atcaatctta ccagagcggt attgcccacg
    55381 gataaagtgt tctttgagtt cttcatcagt tggatgatag aggtttttaa agaccttaat
    55441 cttttcagca cgaatctcgt cttttgtgaa gcttgctggt ttgtccatgg cgaggagcga
    55501 aagaagttgt agagtgtggt tttggaccat gtcacggagg gcaccggatt ggtcatagta
    55561 gccaccacgt tcttctacac ccaagcgctc cgcaaaggta atttgaacat tgtcgataaa
    55621 atccttgttc caaacgtttt caaaaatcaa gtttgcaaag cgaactgcaa agatgctttg
    55681 gatcatttcc ttaccaagat aatggtcgat acggaaaatt tgttcttcgt caaatgttgc
    55741 taggagttcg tcattcaact tgcttgcagt tgcgtaatct gtaccaaatg gtttttcaac
    55801 gatcaagcgc tcaaaacctt tgccatcgac aatgttttca gatttgaggt gtttggcaat
    55861 ggttccaaag aactgaggtg ccatagacaa gaagaagagc ttattgtgtt cagcttggta
    55921 tttttcatta agctcagctt gtaattgacg caaagcaata taatgttccg aatcattgac
    55981 atcatggctt tgatagtaga agtggctagc aaattcttgg gcttgctcgg tactatctgc
    56041 caaatcaagg atggactcga caactacaga ttcaaaatat tccttactcc aaggtctacg
    56101 ggcagttcca ataacggcaa agtgcttgga aagattgccg gatttatata gtctaaaaag
    56161 ggaagggtag agcttgcgtt tagccaggtc tccactcgca ccgaaaattg taacaataac
    56221 cttagatgac atctagctac ctaatttcta tttttattcc tagtcttgct aggtatgagg
    56281 aaacctcatt tcataaactt aattctaaca taattttccg aaaaatcaaa aattccaata
    56341 cgaggtagaa aaactgcaag gaaatcctta cagtttgagt ttagacgttt aagaccttat
    56401 ctaagaactc tttcagacga gggtgttgtg ggttatcaaa gatttggtca ggtgttccgt
    56461 cttcaaggaa ctcgccatct gcagtaaaga taacgcggtt ggcaacctga cgagcaaatc
    56521 ccatctcatg ggttacgata atcatggtca tgccttgctc agccaattcc ttcataacgt
    56581 taagtacgtc tccaaccatc tcagggtcaa gggcagaagt tggttcatcg aagagcatga
    56641 tgtctggatt cattgctagg ccacgagcga tggccacacg ttgtttttga ccacctgata
    56701 ggctatctgg attggcatta gctttatctg ctagtccaac cttttcaagc aactccattc
    56761 ccaattcctc agcttcttcc ttagtcatca acttgtgctc aataggagca aaggtgatgt
    56821 tgtccaatac agacatatga gggaagaggt tgaagtgttg gaataccatg ccgatatttt
    56881 cacggacgtg gtcaacattg gttgtttttt cagttaaatc atagccgttc acagtgatgt
    56941 gaccgctagt gacttcttct aaaagattga ggctacggag gaaagttgac ttaccagaac
    57001 ctgaaggacc gatgatacaa acaacatctc cttcatagaa cttagtcgta attcctttta
    57061 ggacttcatt ttttccatag tgcttgtgta aatcatttac atcaattttt aattttgcca
    57121 ttaacgaatc ctcttttcta agcgtttcgc tagtctagtc aaaagtgtga taattacaag
    57181 atagaagata gcaaggattg catacatctt gaaactttgg tagttacgag caatgataat
    57241 cttaccagtt tggaagagtt caaccaaacc gatagcagat acgatagttg tatctttaag
    57301 agcgataacg aattggttga caaagtttgg caacatcaat ttagttgctt gtggcaagat
    57361 aatcttacgc atggtttttc cataagagat acccaagctt cggctggctt ccatttggcc
    57421 aactggaacg gcctgaatac caccacgaac gatttcagcg atataagcag ccgcattgag
    57481 tgagagggca attgttccag ctacaaagtc gttaattggg ctttgttggc ctgtgataga
    57541 ctcgatgaag tttggaattc cccagaagat gaaggctgca agaatcatca atggaatacc
    57601 acgaataacg tcaacgaaaa tctcagagat gacgcgaaga gatttgtatg ggctaacgct
    57661 aaacataccg aagataattc cgatgacaat ggcaatagca aatgagataa gagctagagc
    57721 aagagtgata ccaagaccgc taaggagttg tttgtagttg ttttgaagca agccccagag
    57781 cgttgtttcg tcaacagtac ttgttgaagc agttgaagat tcgctagcta ggtatttgtc
    57841 aagaatcttt tggaattcac cgtttgcttt aaggtttgca agtccgttgt tgaacatttc
    57901 aatcagttct ggatttgctc cttttttaac ggcaaaggct gtttcaccga ttggagttcc
    57961 agagattgga gttttcaatt tttgaccttg gctgatagaa tatttgagaa caggttcatc
    58021 atccataacg gcatcaatgg caccagtatt taaactgtca tacattgaag aaccatcagc
    58081 aaaggttttg attttgtagc cgtatttgct ttgattttct gttaggaagg tttgagaagc
    58141 agttccgttt ttaacaccga ctgtctttcc ttttagatct tcataagaag caatattgct
    58201 tgattctttg acaccaagaa tggtattagc agtgtagtat gattctgaga agtcaaaagt
    58261 tgccttacga gcatctgtga cagacatacc agcgatgata ccatcggctt gaccagcttg
    58321 gacagcactg atagcagcat caaaaccagg gttggtgatt tcaatttcaa aaccttggtc
    58381 tttagcgatt gccttaatca attccatatc aataccagtg tattggttgc ttgaattttg
    58441 gaaaacaaaa ggtgcaaaag aagaatcgct ggcaatgata tatttagcct taacaggaat
    58501 ggcttttaat cctgcgagag tagttgtagt tggcactgct gaagatgatg aagcagtcca
    58561 tttcttgata attttatcaa gactaccatc ttttttcatt tcagacaagg cttggttaaa
    58621 ttcagtaacc aggtgctcgt atttacttcc ttttttcaca ccgaaagcaa aacttcctac
    58681 agcttcacca tccatttcaa tatggaggtc ttgaccttgg ttaatggcat attcgataac
    58741 aggtttgtca tccatcatgg catcgatggc accagcactc aagctgttgt tcattaaatc
    58801 accagtgtca aatgttttaa tagtaaagcc gtatttatct ttgattgttt caaggaaacg
    58861 ttgagcggca gttccgtttt taacaccaac ggttttgcca gttaattggt cgtacttgct
    58921 aattttgtgt gactttgtag tagcaatgac aacttttgta tcatagtaag tatcagacat
    58981 ggtgaagact ttttcacgtt ctttagtctt tgtcatccct gccatgatag cgtcggcttg
    59041 cccagcttga accgcattga ctgctgcgtc aaatccagga taggacatct gaatgttcca
    59101 gcctttaatc tcagcgactt tgttaataat gtcaacatca attcctttat aagtttgatc
    59161 tgaatcttta aactcaaaag gtgcataggc ggtatcagaa acaatcttaa tcgtttctgc
    59221 tttggcaata cctaatgaga aaattgggaa taaaattagc aaaaatgcta gaaatttttt
    59281 cttcattttt agtctccttt tccgaatatt ctctcattat atcagaaaaa gtaaaaaaag
    59341 gcaaattttt atatttttcg tgtcagaaaa tataacatcg attttttcct ttccttgaat
    59401 tgctattaaa aagtgctata ataatagtat atatagaaga aaagaggacg gggatatgaa
    59461 gaacaaaaga atatttaaag acttccaagc ttcaaaaatg agtttaaaca tttacacaag
    59521 ccccttgtta gcctttgttt ttgtcttcat aggagagttt gtggctttta ctttgtatgg
    59581 tattggcttg ttagctctca tcggacttgc tagaaatttt ggagaggctg gtcaaaatct
    59641 tgcaagctac ttgcagacct tgcatcagag cttgacggat aaaacaagtg actttcgttt
    59701 aattttagga ttactggcct ttggttttat tcttaacact gtgttcagat ggacaagaaa
    59761 agttgagaaa agacctattc gaaccttggg attttataga gagaatttcc tcagcaatct
    59821 tctgaaagga tttagtctag gcctggcact ttttcttctg accttgttag gtttagtggt
    59881 cttaggtcaa tatcgtttgg aatccattca cttgaatcct tattctcttg cctttgtcgt
    59941 ctttactatc ccattttgga ttttacaggg gacagcagaa gaagtggtgg cccgtgcttg
    60001 gctacttcct caattggcct caagaaccaa tctaaaacta gctattctta tatctagcct
    60061 gttctttacc ctgcttcata tgggcaattc tggtctcacc cctctatctc tagtaaatct
    60121 ctttttattc ggagttgcca tggctcttta ccttctcaaa actgatacag tttggggtgt
    60181 tgcaggtatt catggtgctt ggaattttgc tcagggtaat ctctttggga ttttagttag
    60241 tggtcaaccg tcaggaacgt ctctgatgac ctttttacca caaggcaatc aagattggct
    60301 atcaggtggt tcttttggca tagaaggttc cattatgaca agtctggtat tactactgct
    60361 gattgtctat cttgctaata aattaaagaa agaaaatgaa aggatgtgac ttcggtccgt
    60421 ccttttcttc gtgaaaatac tataagtatg ctaaaatagg aatagcacat ggagagagga
    60481 ttcttatgat caatcacatt acagataatc aatttaaact agtatcaaaa tatcaaccat
    60541 caggagatca accccaagct atcgagcagt tggtggataa cattgagggg ggagaaaaag
    60601 ctcagattct gatgggggcg actggaacag ggaagaccta tactatgagt caggtcattt
    60661 ctaaagtcaa taaaccaact ctggttattg cccacaataa aactctggct ggtcagctct
    60721 atggggagtt taaggaattt ttccctgaaa atgcagttga gtatttcgta tcctactatg
    60781 attattacca gccagaggcc tatgtccctt ctagcgatac ctatattgag aaggatagtt
    60841 ctgtcaatga cgagattgac aagcttcgcc actcagctac ctcagccctt ttggagcgta
    60901 atgatgttat tgtcgtggcc tcagtctctt gtatctatgg tttgggttcg cccaaggaat
    60961 acgctgatag tgtcgttagt ctccgtcctg gtctagagat ttctcgtgat aaactcttga
    61021 atgacttggt cgatattcag tttgaacgta atgatattga tttccaacgc ggaagatttc
    61081 gcgttcgtgg ggatgtggta gagattttcc cagcttcccg agatgaacat gcctttcgag
    61141 tagaattttt tggagacgaa attgaccgta ttcgtgaagt tgaggctctg acaggtcagg
    61201 tgttgggaga agtggatcat ttagcgattt tcccagcgac acactttgtg accaatgacg
    61261 accacatgga agttgccatt gcaaagattc aggccgagtt ggaagaacaa ttagctgtct
    61321 ttgaaaagga aggtaaactg cttgaagccc agcgtttgaa acagcggaca gagtatgata
    61381 tcgaaatgtt acgtgagatg ggctatacca atggggttga aaattattct cgccacatgg
    61441 atggacggag cgaaggagag cctccttata cgcttctcga cttcttccca gatgatttct
    61501 tgattatgat tgacgagagt catatgacca tagggcaaat caagggcatg tacaatggag
    61561 accgttcgcg taaagaaatg ctggttaatt atggtttccg tttgccgtct gctttggaca
    61621 atcgtcctct ccgtcgggag gagtttgaga gtcacgttca tcagattgtt tacgtttcag
    61681 cgacacctgg tgactatgaa aatgaacaga ccgagacagt gattgagcaa atcattcgtc
    61741 caacgggact cttggatcca gaggtggaag tccgtccgac tatgggacag attgatgacc
    61801 tcttgggtga aatcaatgcc cgcgttgaaa aaaatgagcg tacctttatc acaactttga
    61861 ccaagaaaat ggcagaggat ttgaccgact acttcaagga aatgggtatc aaggtcaagt
    61921 acatgcactc ggatatcaag accttggaac ggacggagat tatccgtgac ctgcgcttgg
    61981 gtgtctttga tgtcttggtc ggaattaacc tgctccgtga aggaattgac gttcctgaag
    62041 tgagcctcgt agctattctc gatgctgaca aggaaggttt ccttcgcaac gaacgtggac
    62101 tcatccagac tattggacgt gctgctcgta acagtgaagg ccatgtcatc atgtatgcag
    62161 acacggttac ccagtctatg caacgtgcta tcgatgaaac tgcccgccgt cggaaaattc
    62221 agatggccta taatgaagag catggtatcg taccacagac aatcaagaaa gaaatccgtg
    62281 acctgattgc cgtgaccaag gcagttgcta aggaagagga caaggaagtc gacatcaata
    62341 gcctcaacaa acaagagcgc aaagaactcg tcaagaaact agaaaaacaa atgcaagaag
    62401 ccgtcgaagt gcttgacttt gaactggcgg ctcagatccg tgatatgatg ttggaagtcc
    62461 aggccttgga ttaggggaat agtatgattt atttaagaaa gttaaagaga gaagatttga
    62521 tgtctttatg ggaaatggct tattcacaac ttaatccagt ttggaaacag tatgatgctc
    62581 cctattatga tgattatcag tatttttcaa attttaaaga attcgaacta caaaaatcag
    62641 aatccatttt aagcaactca aatcgccttg gtatttttgt tgatgataaa ctagttggga
    62701 ctgtttcgcg ttattgggta tgtaaacaaa caagatggat ggaattggga attggtattt
    62761 atgataaaaa attctggaac actggtattg ggaaagttgc tatgttgcag tggatagata
    62821 ggacgtttca ggattacttg gagttggagc atctgggttt gacaacttgg tcagggaata
    62881 ttggtatgat gaaacttgct gaaaaattaa gaatgaaaaa agaagctcat attccaaaag
    62941 ttcgttatta tcaaggtaaa tattttgata gtattaaata tggtattttg agagaagact
    63001 gggagaaaat aaatgacggt tattatcaaa tcaatggaaa ctcctgaaga gatagaagat
    63061 aaatcccttg ttcactggca aacgtggaga gaggcttatg atgacctttt gcctgcggaa
    63121 tttcaggata caatgacatt agaaagatgt cgattcttta gtcaaaagta tccagaaaat
    63181 acattgattg cgatggatgg cgtgaaggtg gttggtttta tcagttatgg caattttcgt
    63241 gatgagacta ttcaagctgg tgaaattatt gctttatatg ttttaaaaga ctattatgga
    63301 aaaggtatcg cacaaaagtt aatgaaagca gctttgactg ctcttaatca tttttctgaa
    63361 attttcttat gggtattgaa agataacaag cgcgccattg ctttctatca aaaaatgggt
    63421 tttacttttg atggacaaga aaaaatactt gaacttggaa agcctataaa ggaaaaacga
    63481 atggtgttct attctaaata attttaaaaa agtaaaagat aatatctctg gtagtaagtc
    63541 tgaaaattta ataaattaga aagcgagtaa atttatgtcc cgttcccaat taacaatttt
    63601 aacaaatatc tgtctgattg aagacctcga aactcagcgc gtggtgatgc agtatcgcgc
    63661 ccctgaaaac aatcgctggt ctggttatgc ctttcctgga ggtcatgtag aaaatggcga
    63721 gtctttcgca gagtctgtca ttcgtgaaat ctatgaagaa acagggttga ctatccaaaa
    63781 tcctcaactt gtcggcatta aaaattggcc actagataca ggtgggcgct acattgtcat
    63841 ttattataag gcgactgagt tctctggtag ccttcggtct tcagatgaag gagaagtttc
    63901 ttgggtgcaa aaagaccaga ttccaaactt ggatctggcc tatgatatgc taccattgat
    63961 ggaaatgatg gaagctcccg acaagtcaga gtttttctat cctcgccgta cagaagacga
    64021 ttgggaaaag aaaatcttct agtcttttac taaataacct agctgatcca aggcctcctc
    64081 gatatagtgg aggtcttgtt gtgtttcggc ttcgactagg tggtaatgga tgccatctgt
    64141 caattcagat agaggtctaa agtcagaatg ctcgacttgt tctagaaaat gttgcacatc
    64201 tctgcgacaa gacagtttaa gcaaggtttc aatttctcca taaacgggat ggtcaatcaa
    64261 ggtattctgg acatgcccac cattatcgac aatagcaagg agttcctgac cgatttcttc
    64321 aacttcatgt ttcactttga aaagtttgtg aacataagga ttggtatcaa tttgcttata
    64381 gatgtagcca cgattggtgg ataggatagg agcgccatcg gctctcaaaa ttgcaatgtc
    64441 ctgcacaatg acctgacgtg tgacatgaaa atgttccgcc aaactttggc cattaagggc
    64501 tttaggagct tctttcaaga gttggagcag ggcttgtttg cgatcttttg tcatagcttt
    64561 tccttttaac ggcgttttcg aagcacttta tagacagcta gtgctaatgt atagtctacc
    64621 atactatgga taattgtgcc aaatccaact agtacaaata gaacatagaa catgttttct
    64681 acattggtac ccgaagttgc gtaaaaaagg acacaggcta atacttcagc aagggcatga
    64741 acaacagcca aaacaaaatt gaaaacccag gaagattttg gtttatctag ggtatcgggg
    64801 aatttttgta ggtaaagagc tcctaaagca ccaaaagata tatgggaaaa ggcccgaaaa
    64861 acgataacaa tgggatagcc agccatcaaa aatccaaaac tagaggctag gatgacaaaa
    64921 actgccatca agggcgacaa gaacatggct ataaaaatag cgatgtggct ccccaaagta
    64981 taggaagcag gtggaatgac aatcttgaaa ggcataacaa ttggaatcaa aatcgcaata
    65041 gccgttaaaa gggctgtcat tgtcataaat tgtgtctttt tccgtgtatt cacaagaatc
    65101 tcctttttaa ctgcatatac actagtatgg tacaataaac cagacaataa agcaagaatt
    65161 tacttgggtt tatagatcat tttttagtta aaagttatag tagattgaaa ctagaatagt
    65221 ccacctctac ttctaaaaca ttgttagaaa tcgatttggc tgtcctgatc gatttgtcct
    65281 gttcttattt cgttttacta atagtaaaga tttcattaaa aagaaactgt atagagcaaa
    65341 atctccacct tcaggtttga aagcggagat tgtttttatt ttttcaaggt ttgtagtcgt
    65401 ggaacaatgg ctagggttag aattgcagaa atgaccaatt cagcaattga atttgttgag
    65461 ataacggttg ccagaagaag ttggatattt ccattataaa catttccaaa taggaagaag
    65521 attcctccaa ggacaaagat agtatttgtc aaggaaccaa gggccccagc taaaatcaga
    65581 ccagtcttgt ttttcatcag tttatagact aagtaaggag ttaaaccaat caaaatacgt
    65641 gggacaatgg caatgatagc tgagtagatg tttccgtttg gtacgaaggg agagaagagg
    65701 tagcttgtcg gtagaatcgt aatcgtgtta accgtcaagc taagtaatcc catcaaaaat
    65761 ccaagtgtaa ccccaactcg tggaccataa ataatgctgg caataatgac aggaatatga
    65821 acaatggtcg gtttgattgg aaatggaaaa aggttaaaga taagtgagct cagaaagtgt
    65881 atcacgagca tggtagcaaa aaagatagca atgggtgcaa tattagagcg ttttttcatc
    65941 gatagtttcc tttattcttt ctaaaataat tgtgaggtca gctaaagctc ctcgtccgtg
    66001 gtctccacaa gctagtaggg attccttagg agcaatcagc tgatagccgt aagtttctaa
    66061 tgttttcaga ttattctgag ttactggatg gtcatacatt tttgtattca tagcaggagc
    66121 tattagtttg ggaatatgac ttggtagggc tagagctgta ctggttacca tgttgtccgc
    66181 aaatccgtga gctagttttg caatagtgtt agcagttgca ggtaccacga taaataaatc
    66241 tgcttttttt ccaagttcga tatgattgac ctgatcagga tagggttcct tcatgacatc
    66301 caagtggaca ggattctgtg agagtacctg tagtgtcaaa ggttggataa actctgtagc
    66361 agcctgagtc attaagacag tgacttgatg gccttgtttt tttagagaac tgactaaatc
    66421 tgccgactta taagaggcga ttgaacccgt tacagccaag agaatgtttg ccatagtttt
    66481 cctttctaag aatgataggc ttgaattttt tcaaggagga gttctgcaat ttcttcttta
    66541 gtctggactg tttgaagctg atttttctca acaaatatag ctcggtgctg acctgctgaa
    66601 atttgagtca ggtcattcgc gatgattaaa tctgcttgat tcttgataag actttttcgt
    66661 gcaatgtcaa ccagatgatc ttcggtaaca tcaaccagca gtttgaaacc aatcagatga
    66721 atagtaggat tccattcctt gactagggat atgattttgg gtgtcttttt aaggaacaaa
    66781 acctgaacct catcagttga agaaatcttg gcctgatgat tctgcttgct taaaaattct
    66841 tttagattgg agctagcctg aacttcctca agccctgtca tataaacagg agtgtagtca
    66901 gaaacagcca ttgagtggat caagacctga taatcctgaa cacgttcttg catttctatt
    66961 agaaggtcct tggtattggt aatttctcga atacttaggt taggatgagg ctctggcttc
    67021 agagctcgtt ttgtcgtaat taaacaaact tcatgccctg caaaaagcaa agtctctgtg
    67081 ataattttcc ccaagtgacc tgtagaatgg ttagtgatag agcggacgct atcgatagct
    67141 tcactggtac cgcccgatgt aactaaaatt ttcatagcac tattgtacac aaaaataagc
    67201 ggtaagtaaa atgaaagtga taaatttttg gtaaaaacga agatttatta tagtttcaaa
    67261 ctataaagcc atataaaatt taagaaagga ctctaaaagt cttaaaaaca gagatattta
    67321 cgaacgttta gagagtttta ggatgttaaa aatcttgttt tgtgatataa tgaattatca
    67381 tataagaggt tagaggaatt ttgaatgaaa acagatattg aaatcgcaca gagtattgag
    67441 ttgaagccaa ttgttgatgt tgtagagaaa cttggtattt cttacgacga tttggagttg
    67501 tacggaaagt acaaggctaa actcagcttt gataaaattc gtgcagttga gagcaatcca
    67561 gtcggtaaat tgatcttggt tactgccatc aacccaacac ctgcaggtga aggaaagtcg
    67621 acgcttacca ttggtcttgc ggatgccttg aacaagattg gcaagaaaac catgattgct
    67681 atccgcgaac cgtctcttgg tccagtcatg gggatcaagg gtggtgctgc tggtggtggg
    67741 tatgcacaag ttctgccaat ggaagacatc aacctccact ttactggaga tatgcatgct
    67801 attacaactg ccaacaatgc cctttctgcc ttgattgaca accacttgca ccaagggaat
    67861 gagctggaaa ttgatcaacg tcgtatcctc tggaaacgcg ttgtggactt gaacgaccgt
    67921 gcgctccgcc atgtgactgt tggtcttggt ggtcctctaa acggtattcc acgtgaggat
    67981 ggttttgata ttacagttgc ttcagaaatc atggcaattc tttgcttggc aacggacatc
    68041 gaggacttga aacgtcgttt ggcgaatatc gttattggtt atcgctatga ccgtacgcct
    68101 gtttctgtag gtgatttgca ggttgagggt gccttggctt tgattttgaa ggatgctatt
    68161 aagccaaact tggttcagac aatttacggt acacctgcct ttgtacatgg tggtccattt
    68221 gccaatatcg ctcatggctg taactctgtt ttggcgacga caacagccct tcacttggct
    68281 gattacactg ttactgaagc tggttttggt gcggatcttg gtgctgagaa attccttgat
    68341 atcaagacac caaacttgcc aacatctcca gatgcagttg ttattgtcgc aacccttcgt
    68401 gcccttaaga tgaatggtgg tgtggctaaa gacgctctga ctgaagaaaa tgtagaggca
    68461 gttcgtgcag gttttgctaa cttgaaacgc cacgttgaaa atatccgtaa gttcggtatt
    68521 ccagcagttg tagctattaa cgaatttgta tctgatacag aagctgaaat tgcagtctta
    68581 aaagaactct gtgcctcaat cgatgtacca gttgaattgg ctagtgtctg ggctgatgga
    68641 gcagaaggtg gagtagcact tgccgaaaca gttgttaaga caattgctga aaatccagct
    68701 aactataaac gtttgtacga taatgacctt tctgtccaag aaaagattga aaaaattgtc
    68761 actgaaatct atcgtggtag caaagtgaac tttgagaaga aagctcaaac acaaattgct
    68821 caaatcgttc aaaacggttg ggacaaattg ccaatttgta tggctaaaac tcaatacagt
    68881 ttctcagaca atccaaatgc gcttggagca ccagaaaact ttgaaattac cattcgtgaa
    68941 ttggtaccaa aattaggtgc aggcttcatc gttgccttaa ctggtgatgt tatgaccatg
    69001 ccaggtcttc caaaacgtcc agcagctctc aacatggatg ttgaaagcga tggaactgta
    69061 ctaggcttgt tctagtggat tgaaattgac tttaagtgag tttggaaata atatccaagc
    69121 tcattttttc tcagactgca agcagttcat caataagatt tatactcttc gaaaatcttt
    69181 tcaaactacg tcagcttcac cttgccgtag gtatatgata ctgactctgt cagttctatc
    69241 cacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt gctctttgat
    69301 tttcattgag tataagtaga tagaaaagtt atatactatc tattgaaaat attataaatc
    69361 agatacaaag acaggtgaaa ccttctgtgt tatactagag atatgttaga tttgaaagaa
    69421 tacggtatcg tcatgtggcc ggaggagaaa gtcatttctt tccgtgagaa acttctcgct
    69481 tggtatgatg aaaacaaaag agatttgcct tggaggagaa gtaaaaatcc ttatcacatc
    69541 tgggtatctg aaatcatgct tcagcagacc agggtggata cagttatccc ttactacgaa
    69601 agatttttgg actggtttcc aactgtcgaa agtctggcaa ctgcgcctga ggagagttta
    69661 ctgaaagctt gggagggctt gggctattat tctcgagttc gcaatatgca ggctgcagcc
    69721 cagcagatta tgactgactt tggtggccaa tttccaaata cctatgaagg aatttccagc
    69781 ttgaaaggga ttggacctta cacagcagga gccatttcca gtattgcttt taacttgcct
    69841 gagccagctg tagatggtaa tgtcatgcgg gtcttggcgc gtctgtttga agtcaaccac
    69901 gatattggga ttccaagtaa tcgaaaaatt tttcaggcaa tgatggagat cttgattaat
    69961 ccagatcgtc cgggtgattt taatcaagcc ttgatggact tagggtctga tattgagtct
    70021 cctgtaaatc ccagacctga agaaagccca gtcaaggact ttagtgcggc atatcagaat
    70081 ggaaccatgg accgttatcc aattaaatct cctaagaaaa agccggttcc tatttatctt
    70141 aaagccttag ttgtgaaaaa ttctcaagga caatttttac ttgaaaaaaa tgaaagcgaa
    70201 aagctcttgg caggtttttg gcatttcccc tttatagaag ttgataactt ttcgcaagaa
    70261 gagcagtttg acctctttca tcaggttgcg gaagaaagtg tgaactctgg ccccagtcca
    70321 gaagagagtt tccagcagga ctatgaccta gatgttgatt ggcttgatgt ttgttttgat
    70381 acagtccagc atgtttttag tcatcgaaaa tggcatgtac agattgtagc aggtcaggtg
    70441 agtgacttcc atgatttttc agatagggaa gttcgttggc tttcaccaga agaattcaag
    70501 aattacccac ttgccaaacc ccaacaaaaa atctggcagg cttatgcaca agccaactta
    70561 gacagtagcc aagactagct attgtgtctt ctgactattt tttggtataa tagtagagaa
    70621 aaaggtgaac atatgaaaaa aatactaatt gtagatgatg agaaaccaat ctcggatatt
    70681 atcaagttta atatgaccaa ggaaggttac gaagttgtaa ctgcttttaa tggtcgtgaa
    70741 gcgctagagc aatttgaagc agagcaacca gatattatta ttctggattt gatgcttcca
    70801 gaaattgatg gtttagaagt tgctaagacc attcgtaaga caagcagtgt gcccattctt
    70861 atgctttcag ccaaagatag tgaatttgat aaggttatcg gtttggaact tggggcagat
    70921 gactatgtaa cgaaaccctt ctccaatcgt gagttgcagg cgcgtgttaa agctcttctg
    70981 cgtcgttctc aacctatgcc agtagatggg caggaagcag atagtaaacc tcaacctatc
    71041 caaattgggg atttagaaat tgttccagac gcctacgtgg ctaaaaaata tggcgaagaa
    71101 ctagacttaa cccatcgtga atttgagctt ttgtatcatt tagcatcgca tacaggtcaa
    71161 gtcatcacgc gcgaacactt gcttgagact gtctggggtt atgactattt tggtgatgtc
    71221 cgtacagttg atgtgactgt acgacgtctg cgtgagaaga ttgaagatac gcccagccga
    71281 ccagagtata tcttgacgcg ccgtggtgta gggtattaca tgagaaataa tgcttgattt
    71341 actgaaacaa accattttta ccagagattt tatctttatc ctgattttgt taggtttcat
    71401 ccttgttgtg accctcttat tactggaaaa tagacgtgat aatattcagt tgaagcaaat
    71461 caatcaaaag gttaaagatt tgattgcagg agattattcc aaggttcttg atatgcaagg
    71521 tgggtctgaa atcaccaata ttaccaataa tttgaatgac ttgtcggagg ttattcgtct
    71581 cactcaggaa aatctagaac aagagagtaa gaggctaaat agtattctgt tttatatgac
    71641 agatggggtt cttgcgacca accgtcgggg tcagattatc atgattaacg atacagccaa
    71701 gaagcaactg gggttggtta aggaagatgt tctgaataga agcattttgg aattgctcaa
    71761 gatagaagaa aactatgaat tgcgtgattt gattacccaa agtccagaat tgttgctaga
    71821 ttcccaagat atcaatggcg aatatttgaa ccttcgagtt cgctttgcct tgatacgtcg
    71881 agagtctggc tttatttcag gtttggtggc tgttttgcat gatacgacgg agcaggagaa
    71941 ggaagaacgc gaacgaagac tctttgtttc caatgttagc catgagttac ggactcctct
    72001 gactagcgta aaatcctatc ttgaagcctt ggatgagggg gctttgtgtg aaactgtagc
    72061 accagacttt atcaaggttt ctcttgatga gaccaaccgt atgatgcgca tggtgacgga
    72121 tctcctccat ctttcacgta ttgataatgc taccagtcac ctagatgtgg aactgattaa
    72181 cttcactgct tttattacct ttatcctcaa tcgttttgac aagatgaaag gacaggaaaa
    72241 ggagaaaaaa tatgagttgg tgagagatta tcccatcaat tctatctgga tggaaattga
    72301 tacagataag atgacgcagg ttgtcgacaa tattttaaat aatgctatta agtattcgcc
    72361 agatgggggt aaaatcactg tcagaatgaa gacaactgaa gaccagatga ttttatccat
    72421 ttctgaccac ggtttgggga ttcctaagca ggatttacca cgtatctttg accgtttcta
    72481 tcgtgtggat cgtgctagaa gtcgtgcaca aggtggtaca ggtctaggac tgtctatcgc
    72541 taaagaaatt atcaaacaac ataagggctt tatttgggcc aagagtgaat acggcaaggg
    72601 ttcaaccttt accattgtgc tcccttatga taaggatgca gtgaaagaag aagtatggga
    72661 ggatgaagta gaagactaga atgagtgaaa taggctttaa atacagtatt ttagcgtcgg
    72721 gttccagtgg aaattctttt tatctggaaa cctcaaaaaa gaagctttta gtagatgcag
    72781 gcttgtctgg caagaaaatt accagtctgc tagctgaaat taaccgtaag ccagaagacc
    72841 tggatgccat cttgattacc catgagcatt cagatcatat ccatggagta ggcgttttgg
    72901 ctcgcaagta tggtatggat ctttatgcca atgaaaagac ctggcaagct atggaaaata
    72961 gtaaatatct tggcaaggtg gattcttcgc aaaagcatat ttttgaaatg ggtaaaacca
    73021 aaacctttgg agatatcgac atcgagagtt ttggtgtaag ccatgatgca gtcgcaccgc
    73081 agttctatcg ctttatgaag gatgataaga gttttgtcct cttgacagat acaggttatg
    73141 tcagtgaccg tatggcgggc attgtcgaaa atgcggatgg ttatcttatc gaggccaacc
    73201 atgatgtaga gattttgcga tcaggttctt acgcttggcg actcaaacaa cgaatcctat
    73261 ctgaccttgg tcacctttct aacgaggacg gtgctgaagc tatgattcgg acgctaggaa
    73321 atcgtactaa gaagatttac cttgggcatt tatctaagga aaacaatatc aaggaactgg
    73381 ctcatatgac catggtcaat cagctggctc aagctgatct gggagtcgga gtagacttta
    73441 aggtttatga tacctcacca gataccgcaa caccattgac agagatatag aaagaacgct
    73501 gagaaggtgt tctttttata ttgactggac acctaaaaag taatacaatg gtgttaccat
    73561 taaaaaaggg agcacaaaag atgactacta ttacattaaa agtttctgaa gctgataaaa
    73621 catttatgaa agcaatggct aagtttgaag gagtttccct ttcggaactt attcgcacca
    73681 aaactcttga agccctagaa gatgaatacg atgctcgtgt ggcagattta gcctatcaag
    73741 agtatttaga agacttggaa aaaggagttg aacccattac ttgggaagaa atgatccatg
    73801 atttaggctt gaaggatgaa taatttgtat aaattagttc caacaagacg ttttatcaag
    73861 caattgaaaa aattggaccg ttatacgcag aagctaatta caaactattt acaaaccaat
    73921 gttttggaag acccaagacg acacggaaag gctttggttg gtaatcgcgt tggtcaatgg
    73981 cgctatagaa ttggtaatta tcgagttatc gtacaaattg tagatgatga attagtcgtt
    74041 gctactctag aagttggtca tcggagagat atttattgaa ttactttttt caagtaaatt
    74101 ttcattcttt aaaatatgat ataatagggc ttacaatata agagaggttg ctgatgacaa
    74161 tagatattag tgaagaaagt ttggctaaag aatcggctga cttattaaaa attcttttaa
    74221 aagatcgaac gacaaagaaa tcaattgttt gggctacgca ttcttatgaa ttgttaggaa
    74281 agggatttgc tccaagtgat cgcatcaatc caagtaaggt tactggaaac tttgccaact
    74341 tgattcagcc cagatctgaa aaatccaaat atgaacaaaa agatcggaca aaaataaggg
    74401 cagaagtgtt tacaccaacg tggttggtcg caaagcaaaa tggatatgta gaatcgaaat
    74461 taggctcgtt aagtcttgag gagtatgtgg acttacgatg gttagaggta acttgtggtg
    74521 aagcacctta tatggtaacg agatatgata ccgtaactgg tgaggaaatt ccattatctg
    74581 agcgagttgg ttttgttgat agaaaactgc aacggattag tcgtgaggtt tcagatgaag
    74641 tcacatttta taaacttgta aaagatgctt atcatgcttc gtatggttat gagtatcaag
    74701 gagattctct ccttttggcg cgtgagaatc ttttggcaac ttttgaggac tattatctag
    74761 ctaagactgg aaatcaacca acattagagc aaaagaaaga aattgcgact attatctctt
    74821 acaatgtctt tcagatggat ggattgaaaa aaagtagtcc ttattcagct aaacaaaagc
    74881 aatctcaaca attgagtttg tttgcggatg agctagaagt ccaagaagta gaagaatcta
    74941 aaacccatat caaagactgg aaaaagaata gaatgatagg ttttgagcgc ctatctagcg
    75001 aggaaagtga aatgaaattt gatgtcgtga taggaaatcc tccgtatcag gaaacaggag
    75061 aagccagaga tgagccgata tatcactatt ttattgatga agcttataaa atcgcagata
    75121 aatctatact aatcacccca gcaaggtttt tatttaaagc tggtcaaact cctaaaaatt
    75181 ggatggaaaa gatgcttgaa gacaagcatt taaaagttca attctatgaa cttaaaagcg
    75241 gtaaagtatt tacaggaacg gatattaagg gtggagtagc aataacttat cgtgatgttg
    75301 ataaagattt gggaccaatc ggagtattta ctatttttga aactttgaat ggtattgtaa
    75361 aaaaaatcga aaaacatcca gaatttgaaa ctttttctga tttagtttat cctcaaggta
    75421 tttatagatt ttcaaataaa cttttttctg attatccaaa tgctgaaaag ctgcaaggaa
    75481 aagggacaaa aaataaaatt gtttcgaaat cactaactca gttagatttt gttttcaaaa
    75541 acaacgaaga aaaagaccat gttgctctac ttggaagaat tggctccgaa cgtgtttatc
    75601 gatatattaa taaaaaatat ttagatttac cggaaacatt cgaaaattat aatgtttttg
    75661 taccagaagc taatggaagt ggtgccttag gtgaagtctt atcaacaccc ctaatcgggg
    75721 aacccctaat cgggcataca gatacttttt tatctattgg taattttaaa acaaaatttg
    75781 aagccgatgc ttgtattaaa tttattaaaa ctaaattcgc tagagtatta ttaggtgttt
    75841 tgaaagttac tcagcataat tcacgcaaaa cttggtatta cgtccccctc caagacttta
    75901 cggtcaattc ggacattgat tggacacaat cagtgactga tattgaccgc cagcttgatc
    75961 aaaaatatga cctttcccct gaagaaattg cctttattga gaatcatgta agggagatgg
    76021 attagaaaag tatttttatt tgacaaatag tgctcaatga tctaaaatga ctatatagga
    76081 ttaggtcagg aagcatacga tgccctgacc ctttttgtac ttatgagatg agaaagtcat
    76141 ttgttagata aattgacttc gttagcaaac gttcaaaaaa ggaaaactta tgccagtaga
    76201 aattaaaacc actaaagaaa ttcatcctaa aatctatgcc tacaccacac cgacagtaac
    76261 cagtaatgaa ggctggatta agattgggta tacagaacgt gatgtcacac aacgtatcaa
    76321 ggagcaaacg catacagctc atatagctac agatgtctta tggactggtg atgcagctta
    76381 tacagaagag cctgataagg ggaaaacttt caaggaccat gatttccacc atttcctttc
    76441 tttccatgat gtagaacgtc gtcccaagac ggaatggttc tattttaatg gaactcctga
    76501 aaaatcaaaa aatctttttg ataagtttgt tcagcatgat ttgtctggtt atcagcctgg
    76561 aaaaggacag gactatactc tgcgacaaga gcaagaagaa gcagttgcta agacattagc
    76621 ttatttccaa gaacatgctg gaggcaagtt tctctggaat gccaagccac gctttggtaa
    76681 aaccttgtct acctatgacc tagctcgacg gatggaagct gtcaatgtcc taattgtaac
    76741 aaaccgccct gccattgcta actcatggta tgatgatttt gaaacattca tagcaggtca
    76801 aacgacttac aagtttgttt ctgaatcaga tagccttaag agtcgtccaa tcttgtcacg
    76861 acaagaattt cttggtattt tagctgacga tgtaagacaa cttgctttta tcagtctcca
    76921 agacttgaaa ggatctgttt atttaggtgg agagcacgat aaactcaaat gggtaactga
    76981 tctgcattgg gacttgttgg ttattgacga ggctcatgaa ggagttgata ccttcaagac
    77041 tgaccaagcc tttaataaga ttcgacgaaa ttttactctg catttgtcag gtacatcatt
    77101 taaagcattg gctaaaggag attttacaga ggaacaaatc tacaactggt cttatgctga
    77161 tgagcaggct gctaagtatt cgtggtctct tgagcaagaa gaggaaaatc cttatgaaag
    77221 cttgcctcag ttgaatctct ttacctatca aatgtctcag atgattggcg aaaagttaga
    77281 aaaaggcgct cagatcgatg gtgaaaatat tgactatgtt tttgacttaa gtgaattttt
    77341 cgctacagat gataaaggga aatttattca tgagcatgat gtcagaaatt ggttagatac
    77401 tctatcaagc aatgaaaaat atccattttc aaccaaagaa ctccgtaatg aactcaagca
    77461 tactttttgg cttttagaac gtgtcgcttc ggccaaagca ttaaaagccc tactagaaga
    77521 acacccaatc tatgaaaact atgagatcgt tctagctgct ggtgacggac gtatgtccga
    77581 agaagacgat aaagtcaaac tcaaatcctt ggacttggtt agaaaagcga tagcagagaa
    77641 tgacaaaacc attaccctat ccgttggtca gctgacgaca ggtgtcacta tccctgaatg
    77701 gacaggtgta ttgatgttat caaatttgaa atcaccagct ctttatatgc aggccgcctt
    77761 ccgtgctcaa aatccttact catggagcga taacaaagga aatcactttc gcaaagaaag
    77821 agcctatgta tttgactttg cgccggaaag aaccttgatt ctctttgatg agtttgccaa
    77881 caacttatcg cttgtaactg cagctggtag aggaacttca gctacacgcg aagaaaatat
    77941 tagagaatta ttaaacttct ttccaattat tgccgaagac cgtgctggta agatggttga
    78001 aattgatgca aaggcagttc taaccactcc tcgccagata aaagctagag aagttcttaa
    78061 acgaggtttt atgtccaatc tcttatttga taatattagt ggtattttcc aagcaagtca
    78121 aacagtttta gatattttaa atgagctgcc agttgaaaag gaagggaagg tacaagatag
    78181 ttctgattta ttagattttt cagatgttac agtcgatgat gagggaaatg cagtagtaga
    78241 ccatgaaatt gtagttaatc agcaaatgcg actttttggt gaaaaagttt atggacttgg
    78301 tgaatctgtt gctgagttag tcacaaaaga tgaggaacga actcaaaaac agctggtcaa
    78361 tgacttgagt aagaccgttt cttcagtgat tgtagaggaa ttgaaagcag attattctct
    78421 aaaaacaagg gaaactgagc aaattaagaa acaaattaca gcaacacttg agaatgaaat
    78481 tcgaaaaaat gatatcgaaa gaaaaatttc tgaagctcat atcaagcaag agttgcaaca
    78541 gcagctcaaa gaagcaaatg ataaagcgca aaaagataag attcaagaag atttggaaaa
    78601 acgtttagaa gaaaataaac tcattcataa agaaaaacta gaacaaacac tcaaaaaaga
    78661 agtggaaaaa atgcctgaga aatttatcga acaggttgag ataaaacgtg tggaacagtt
    78721 gaaacaatca gctcaagatg aaattcgtga ccatttacga gggtttgcaa gaacaattcc
    78781 aagttttatt atggcttacg gtgatcaaac tctaacactt gataattttg atgcctttgt
    78841 tcctgaacat gttttttatg aagtaacagg gattacgatt gatcagttta gatatttgcg
    78901 agatggtggg caggattttg cagggcatct ctttgataaa gcaacatttg acgaagctat
    78961 tcaagaattt cttcgcaaga aaaaggagtt ggcggattat tttaaagatc aaaaagaaga
    79021 catttttgac tatattccac cgcagaagac caaccaaatt ttcactccta aacgagtggt
    79081 gaaaaggatg gtagatgatt tggaaaagga aaatccaggg atttttgatg atccatctaa
    79141 gacttttatt gatttatata tgaagtcagg cctctatatt gcagaacttg tgaagcggtt
    79201 atataatagc aatggcttga aagaggcctt tccaaatcct gaagaacgct taaaacatat
    79261 tttggaaaag caagtttatg gatttgctcc gtctgagatt atctataaca tttccactaa
    79321 ttttatattt ggtaatcttt ctaaagatat cagtaggaag aattttgttt tagcagatac
    79381 cattccagcg gctaaagaag ggagcattca aaagttggtt gattcctatt ttgaaaataa
    79441 ttaaaaagaa ggccgagtca aaattctttg aaatcagaaa aaacgcataa tattgagtgc
    79501 ttttgtactg ccccccaaaa gttagacaga aaaaatctaa cttttggggg gcagttcaga
    79561 caatccttgg tattatgcgt tttattgtgg gaagatgtat aatggattga aataagatat
    79621 gaacaaatcg attaggaaag gaaaattgat ttatagaaat gttttagtag tcgatgcgta
    79681 ctgttataga ttcaacgaac tataaaatct gaagaaagca attttaacca gatcttagaa
    79741 gcagttgtgt actactctaa cttcaataga ctatatcata tagataaaaa acaactccct
    79801 gatgattcaa ggagttgtct atagttaaat tagtttttag aagcttcttg gaattctgga
    79861 tttttccatg cttcgtcaat aatagcttgc aattctttag cagatgcttg cattttttga
    79921 gtttctgcat cgttcaatgg aatgtttact ggacgaacga taccatgtgc accaacaaca
    79981 gctggttgac cgataaagac attctcaact ccgtattgac cttcttggaa tactgaaagt
    80041 ggaagtactg cgttttcatc gtcaaggatt gctttagtga tacgagcaag ggctactgcg
    80101 ataccgtagt atgttgcacc ttttttgttg atgattgtgt aggctgcatc acgaacacct
    80161 tcgaacaatt caatcaattc agcttcttga acattttgag tgtctttaag gaattcttca
    80221 aggtttacac cagcgatgtt agcgtgtgac caaacagcga actcagagtc accgtgttca
    80281 cccatgatgt aggcgtgcac tgaacgagca tccacatcca atttttcagc aagtgcttga
    80341 cggaaacgag ctgagtcaag tgaagtacct gaaccgataa cgcgttcttt agggaaacca
    80401 gagaatttcc aagttgagta agtcaaaacg tcaactggat tagcagcaac aaggaagata
    80461 cctttgaaac cagattcaac aacttgagtt acgattgatt tgttgatagc aaggttttta
    80521 cctacaaggt caagacgagt ttcacctggt ttttgaggtg cacctgcagt gatcacaaca
    80581 aggtcagcgt ctgcacagtc agagtattga gctgcataga tttttttagg tgaagtgaag
    80641 gcaagggcgt gactaaggtc aagcgcatca ccaacagctt tttcatgcaa ttgtggaatt
    80701 tcgataattc caagctcttg tgcaattcct tggttaacaa gtgcaaaagc gtaagatgaa
    80761 cctacagcac catcaccgac aaggataact tttttgtgtt gtttagttga agtcattgtt
    80821 ttaaacatct ccttaatttt attaggggat tttccctaga caacttcatt ctatcacttt
    80881 taaaaaactt tgtcacgaat atgccttata gttctcgatg taaacgtttt agtggtttag
    80941 aggctgaaat agatgggaat ttatggtata atgttgttac ttactaattg tgaaatgagg
    81001 catttattaa tgcaggataa aaatttagtg aatgtcaatc tgacaaagga gatgaaggca
    81061 agttttatcg actacgccat gagtgttatc gtagcgcgag ctcttcctga tgttcgagat
    81121 ggcttaaaac ctgttcaccg tcgcattctc tacggaatga atgaattggg tgtgacccca
    81181 gacaaacccc ataaaaaatc tgctcgtatt acaggggatg tcatgggtaa atatcaccca
    81241 cacggggatt cctctattta tgaagccatg gtccgtatgg ctcaatggtg gagctaccgt
    81301 tacatgcttg tagatggtca tgggaatttt ggttccatgg atggagatag tgctgccgct
    81361 caacgttata ccgaggcacg tatgagcaag attgctctgg aaatgcttcg tgatatcaac
    81421 aaaaatacag ttgatttcgt tgataactat gatgccaatg aacgggaacc cttggtcttg
    81481 ccagcgcgtt ttccaaacct tttggttaat ggagcaactg gtatcgcggt tgggatggca
    81541 accaatattc cacctcataa tctgggtgaa accattgatg cagtgaagtt ggtcatggat
    81601 aatcctgaag tgactaccaa ggacttgatg gaagtcttgc ctggaccaga ttttccaact
    81661 ggtgctcttg tcatggggaa atcaggtatc cataaggctt atgaaacagg taaaggttcg
    81721 attgtcctac gttctcgtac agagattgaa acgactaaga ctggtcgtga gcgcatcgtt
    81781 gtaacagaat ttccttacat ggtcaataaa accaaggtgc atgagcatat tgttcgcttg
    81841 gttcaggaaa aacgcattga gggtatcaca gcagtacgtg atgagtcaaa ccgtgaaggt
    81901 gttcgatttg ttattgaagt caagcgcgac gcctcagcca atgttattct caataacctc
    81961 ttcaaaatga cccaaatgca aaccaatttt ggtttcaata tgctcgctat ccaaaatggt
    82021 ataccgaaaa ttttgtctct tcgtcagatt ttggatgctt atatcgagca ccaaaaagaa
    82081 gtggttgttc gtcgtacacg ttttgataag gaaaaagcgg aagcgcgcgc tcatatctta
    82141 gaaggtctct tgattgcgct agaccatatc gacgaagtga ttcgtatcat ccgtgctagt
    82201 gaaacggatg cggaagctca agctgagttg atgagcaagt ttaagctttc tgaacgtcaa
    82261 agtcaagcta tccttgatat gcgtcttcgt cgtttgacag gtttggaacg cgataagatt
    82321 caatctgagt atgatgacct cttggctctg attgcggatt tagcagatat tcttgctaag
    82381 cctgaacgtg tttctcaaat tatcaaagac gaattggatg aagttaaacg taaattttct
    82441 gataaacgcc gtacagagtt gatggttgga cagattttga gtctcgagga tgaggacttg
    82501 attgaagaat cggatgtctt gattaccctt tctaacagag gctacattaa gcgtttggat
    82561 caggacgagt tcactgctca aaaacgtggg ggtcgtggtg tccaaggaac gggagtgaaa
    82621 gatgatgact ttgttcgtga gttagtgtca actagcacac atgatcatct gctcttcttc
    82681 acaaacaagg gacgtgtcta tcgtcttaaa ggttatgaaa ttcctgagta tggtcggact
    82741 gccaaagggc taccagtagt caatctcttg aaattggatg aagacgaaag tattcagacg
    82801 gttatcaatg ttgagtctga tcgcagtgat gatgcttatc tcttctttac aacccgtcac
    82861 ggtattgtga agagaactag tgttaaggag tttgccaata ttcgtcaaaa tggtctcaaa
    82921 gcgctgaatt taaaggatga agatgagtta atcaatgtct tgttggcaga aggagatatg
    82981 gatattatca ttggtaccaa gtttggttat gcagttcgct ttaatcaatc agccgttcgt
    83041 ggtatgagcc gtatcgccac tggtgtgaaa ggtgttaacc ttcgtgaagg agacacagtt
    83101 gttggtgcca gcttgattac tgatcaagat gaagttctta ttatcacaga aaaaggatat
    83161 ggtaagcgta cagtcgctac tgaataccca acaaaaggtc gtggtggtaa gggaatgcag
    83221 acagctaaaa ttaccgaaaa aaatggcttg ctggccggtc ttatgactgt tcaaggggat
    83281 gaggatttga tgattatcac tgatacaggt gtcatgattc gaaccaatct tgccaatatt
    83341 tcacaaacag gacgtgcaac tatgggagtt aaagtaatgc gcctggatca agatgctcag
    83401 atagtgactt tcacaacggt tgcggtggca gaaaaagaag aagttgggac agaaaacgaa
    83461 acagaaggtg aagcataatg tctcaaaaaa ataataaaaa gaaaaacaag cgaaaaaatc
    83521 tgctgacaaa tatcctagca ggatttctga tattactgtc actggctttg atttttaata
    83581 ctcaaattcg aaatattttc atagtctgga ataccaataa gtatcaagtt agccaggtat
    83641 caaaagaaaa attagaagaa aatcaggata cagaaggcaa ttttgacttt gattctgtca
    83701 aagctatctc ttcggaagct gttctaactt ctcaatggga tgctcaaaaa ttaccagtta
    83761 ttgggggaat tgcaattcct gaattggaaa tgaatttgcc gatttttaaa ggacttgata
    83821 atgttaatct cttctacgga gctggtacaa tgaaacgcga gcaagtaatg ggagaaggaa
    83881 attatagtct agctagtcac catatctttg gtgttgataa tgctaataaa atgttatttt
    83941 ctcctttaga taatgctaaa aatggcatga agatttatct aaccgataaa aataaagttt
    84001 atacttatga aatacgtgaa gtcaaacgtg tgacaccgga tcgtgttgat gaagttgatg
    84061 atagagatgg ggtcaatgaa atcacattag taacctgtga agaccttgct gctacagaac
    84121 gtattattgt caaaggtgat ttgaaagaaa caaaagatta ttcacaaaca tctgatgaaa
    84181 tcctaacagc tttcaatcaa ccatataaac aattttatta atacaaatca gtgaaatcat
    84241 ggatttcact gattttttaa gattttcata aaaatatagt aaaatgaaat aagaatagga
    84301 cgaattgttc aggaca
//
LOCUS       DAVMJI010000005        79985 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.005, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000005 DAVMJI010000000
VERSION     DAVMJI010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79985
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.005"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            481..933
                     /locus_tag="VYR58_000357"
     CDS             481..933
                     /locus_tag="VYR58_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV3621580.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGDFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            952..2289
                     /locus_tag="VYR58_000358"
     CDS             952..2289
                     /locus_tag="VYR58_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV3621581.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2368..3252
                     /locus_tag="VYR58_000359"
     CDS             2368..3252
                     /locus_tag="VYR58_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV3621582.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3252..4085
                     /locus_tag="VYR58_000360"
     CDS             3252..4085
                     /locus_tag="VYR58_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV3621583.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4103..6196
                     /gene="nanB"
                     /locus_tag="VYR58_000361"
     CDS             4103..6196
                     /gene="nanB"
                     /locus_tag="VYR58_000361"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV3621584.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPALIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGDSQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRVESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6208..7310
                     /locus_tag="VYR58_000362"
                     /pseudo
     CDS             6208..7310
                     /locus_tag="VYR58_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
     gene            7484..8182
                     /locus_tag="VYR58_000363"
     CDS             7484..8182
                     /locus_tag="VYR58_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV3621585.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8201..9718
                     /locus_tag="VYR58_000364"
     CDS             8201..9718
                     /locus_tag="VYR58_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV3621586.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETIAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9843..11171
                     /locus_tag="VYR58_000365"
     CDS             9843..11171
                     /locus_tag="VYR58_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV3621587.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11423..12289
                     /locus_tag="VYR58_000366"
     CDS             11423..12289
                     /locus_tag="VYR58_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV3621588.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12305..13144
                     /locus_tag="VYR58_000367"
     CDS             12305..13144
                     /locus_tag="VYR58_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV3621589.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13417..13869
                     /locus_tag="VYR58_000368"
     CDS             13417..13869
                     /locus_tag="VYR58_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV3621590.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            13966..14310
                     /locus_tag="VYR58_000369"
     CDS             13966..14310
                     /locus_tag="VYR58_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621591.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            14594..15238
                     /locus_tag="VYR58_000370"
     CDS             14594..15238
                     /locus_tag="VYR58_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV3621592.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15407..16324
                     /locus_tag="VYR58_000371"
     CDS             15407..16324
                     /locus_tag="VYR58_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV3621593.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLDTARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16342..17226
                     /locus_tag="VYR58_000372"
     CDS             16342..17226
                     /locus_tag="VYR58_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV3621594.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17242..18093)
                     /locus_tag="VYR58_000373"
     CDS             complement(17242..18093)
                     /locus_tag="VYR58_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV3621595.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18293..20350
                     /gene="pbp2b"
                     /locus_tag="VYR58_000374"
     CDS             18293..20350
                     /gene="pbp2b"
                     /locus_tag="VYR58_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV3621596.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKVTTSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVPTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELGNGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTAFSRPMPITAVQALEYSSN
                     AYMVQTALGLMGQTYQPNMFVGTSNLESAMGKLRSTFGEYGLGSATGIDLPDESTGFI
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSVLHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20361..20957
                     /gene="recR"
                     /locus_tag="VYR58_000375"
     CDS             20361..20957
                     /gene="recR"
                     /locus_tag="VYR58_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV3621597.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPVGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21133..22176
                     /locus_tag="VYR58_000376"
     CDS             21133..22176
                     /locus_tag="VYR58_000376"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV3621598.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22260..23633
                     /locus_tag="VYR58_000377"
     CDS             22260..23633
                     /locus_tag="VYR58_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV3621599.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTTYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGVELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            23656..24231
                     /locus_tag="VYR58_000378"
     CDS             23656..24231
                     /locus_tag="VYR58_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV3621600.1"
                     /translation="MIALTDTGLTFTKEPFDRERYEDLRSLLSEMLNQVSDLDADEVA
                     ELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEVGYSPTENILKEI
                     EEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQENQEIADLQFFAID
                     QLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24322..25026
                     /locus_tag="VYR58_000379"
     CDS             24322..25026
                     /locus_tag="VYR58_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV3621601.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25245..26618
                     /gene="ftsA"
                     /locus_tag="VYR58_000380"
     CDS             25245..26618
                     /gene="ftsA"
                     /locus_tag="VYR58_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV3621602.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26635..27894
                     /gene="ftsZ"
                     /locus_tag="VYR58_000381"
     CDS             26635..27894
                     /gene="ftsZ"
                     /locus_tag="VYR58_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV3621603.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27899..28570
                     /locus_tag="VYR58_000382"
     CDS             27899..28570
                     /locus_tag="VYR58_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV3621604.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28580..29119
                     /locus_tag="VYR58_000383"
     CDS             28580..29119
                     /locus_tag="VYR58_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV3621605.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29119..29382
                     /locus_tag="VYR58_000384"
     CDS             29119..29382
                     /locus_tag="VYR58_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV3621606.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29379..30164
                     /locus_tag="VYR58_000385"
     CDS             29379..30164
                     /locus_tag="VYR58_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV3621607.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30173..30961
                     /gene="divIVA"
                     /locus_tag="VYR58_000386"
     CDS             30173..30961
                     /gene="divIVA"
                     /locus_tag="VYR58_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV3621608.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31309..34101
                     /locus_tag="VYR58_000387"
     CDS             31309..34101
                     /locus_tag="VYR58_000387"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV3621609.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            34504..34884
                     /locus_tag="VYR58_000388"
     CDS             34504..34884
                     /locus_tag="VYR58_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621610.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            35078..35368
                     /locus_tag="VYR58_000389"
     CDS             35078..35368
                     /locus_tag="VYR58_000389"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621611.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            35419..36111
                     /locus_tag="VYR58_000390"
     CDS             35419..36111
                     /locus_tag="VYR58_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV3621612.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            36164..38575
                     /locus_tag="VYR58_000391"
     CDS             36164..38575
                     /locus_tag="VYR58_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV3621613.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            38825..39526
                     /locus_tag="VYR58_000392"
     CDS             38825..39526
                     /locus_tag="VYR58_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621614.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            39528..42236
                     /locus_tag="VYR58_000393"
     CDS             39528..42236
                     /locus_tag="VYR58_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV3621615.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLVEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(42332..42823)
                     /gene="tpx"
                     /locus_tag="VYR58_000394"
     CDS             complement(42332..42823)
                     /gene="tpx"
                     /locus_tag="VYR58_000394"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV3621616.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(42946..43875)
                     /gene="psaA"
                     /locus_tag="VYR58_000395"
     CDS             complement(42946..43875)
                     /gene="psaA"
                     /locus_tag="VYR58_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV3621617.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(43907..44755)
                     /locus_tag="VYR58_000396"
     CDS             complement(43907..44755)
                     /locus_tag="VYR58_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV3621618.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(44752..45474)
                     /locus_tag="VYR58_000397"
     CDS             complement(44752..45474)
                     /locus_tag="VYR58_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV3621619.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            45765..47657
                     /gene="pepO"
                     /locus_tag="VYR58_000398"
     CDS             45765..47657
                     /gene="pepO"
                     /locus_tag="VYR58_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV3621620.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(47780..48409)
                     /locus_tag="VYR58_000399"
     CDS             complement(47780..48409)
                     /locus_tag="VYR58_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV3621621.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            49405..51627
                     /locus_tag="VYR58_000400"
     CDS             49405..51627
                     /locus_tag="VYR58_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV3621622.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            51657..52100
                     /locus_tag="VYR58_000401"
     CDS             51657..52100
                     /locus_tag="VYR58_000401"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV3621623.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(52139..52553)
                     /locus_tag="VYR58_000402"
                     /pseudo
     CDS             complement(52139..52553)
                     /locus_tag="VYR58_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(52572..52986)
                     /locus_tag="VYR58_000403"
                     /pseudo
     CDS             complement(52572..52986)
                     /locus_tag="VYR58_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(53117..53763)
                     /locus_tag="VYR58_000404"
                     /pseudo
     CDS             complement(53117..53763)
                     /locus_tag="VYR58_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(53940..54590)
                     /locus_tag="VYR58_000405"
     CDS             complement(53940..54590)
                     /locus_tag="VYR58_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV3621624.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            54702..55544
                     /locus_tag="VYR58_000406"
     CDS             54702..55544
                     /locus_tag="VYR58_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV3621625.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            55620..56057
                     /locus_tag="VYR58_000407"
     CDS             55620..56057
                     /locus_tag="VYR58_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV3621626.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            56125..56427
                     /locus_tag="VYR58_000408"
     CDS             56125..56427
                     /locus_tag="VYR58_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621627.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(56518..57591)
                     /locus_tag="VYR58_000409"
     CDS             complement(56518..57591)
                     /locus_tag="VYR58_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV3621628.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEVFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            57747..58424
                     /locus_tag="VYR58_000410"
     CDS             57747..58424
                     /locus_tag="VYR58_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3621629.1"
                     /translation="MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            58417..59391
                     /locus_tag="VYR58_000411"
     CDS             58417..59391
                     /locus_tag="VYR58_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV3621630.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(59440..61383)
                     /gene="thrS"
                     /locus_tag="VYR58_000412"
     CDS             complement(59440..61383)
                     /gene="thrS"
                     /locus_tag="VYR58_000412"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV3621631.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFEKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(61441..61764)
                     /locus_tag="VYR58_000413"
     CDS             complement(61441..61764)
                     /locus_tag="VYR58_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV3621632.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDPLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            complement(62195..62395)
                     /locus_tag="VYR58_000414"
     CDS             complement(62195..62395)
                     /locus_tag="VYR58_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621633.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            62632..63261
                     /locus_tag="VYR58_000415"
     CDS             62632..63261
                     /locus_tag="VYR58_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV3621634.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            63402..63671
                     /gene="rpsO"
                     /locus_tag="VYR58_000416"
     CDS             63402..63671
                     /gene="rpsO"
                     /locus_tag="VYR58_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV3621635.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            64486..65100
                     /locus_tag="VYR58_000417"
     CDS             64486..65100
                     /locus_tag="VYR58_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV3621636.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(65392..66141)
                     /locus_tag="VYR58_000418"
     CDS             complement(65392..66141)
                     /locus_tag="VYR58_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV3621637.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDCSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            66274..68610
                     /locus_tag="VYR58_000419"
     CDS             66274..68610
                     /locus_tag="VYR58_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV3621638.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKLINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            68712..69389
                     /locus_tag="VYR58_000420"
     CDS             68712..69389
                     /locus_tag="VYR58_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV3621639.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            69376..70173
                     /locus_tag="VYR58_000421"
     CDS             69376..70173
                     /locus_tag="VYR58_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV3621640.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSCGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQEDDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIATLLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            70190..71293
                     /locus_tag="VYR58_000422"
     CDS             70190..71293
                     /locus_tag="VYR58_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV3621641.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            71300..71491
                     /locus_tag="VYR58_000423"
     CDS             71300..71491
                     /locus_tag="VYR58_000423"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621642.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            71594..72613
                     /gene="galE"
                     /locus_tag="VYR58_000424"
     CDS             71594..72613
                     /gene="galE"
                     /locus_tag="VYR58_000424"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV3621643.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            72615..73580
                     /locus_tag="VYR58_000425"
     CDS             72615..73580
                     /locus_tag="VYR58_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV3621644.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(73631..73837)
                     /locus_tag="VYR58_000426"
     CDS             complement(73631..73837)
                     /locus_tag="VYR58_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV3621645.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            73889..74365
                     /locus_tag="VYR58_000427"
     CDS             73889..74365
                     /locus_tag="VYR58_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV3621646.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSHPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            74374..75045
                     /locus_tag="VYR58_000428"
     CDS             74374..75045
                     /locus_tag="VYR58_000428"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV3621647.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            75176..75514
                     /locus_tag="VYR58_000429"
     CDS             75176..75514
                     /locus_tag="VYR58_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV3621648.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            75517..76146
                     /locus_tag="VYR58_000430"
     CDS             75517..76146
                     /locus_tag="VYR58_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV3621649.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            76386..77537
                     /locus_tag="VYR58_000431"
     CDS             76386..77537
                     /locus_tag="VYR58_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV3621650.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            77850..78599
                     /gene="truA"
                     /locus_tag="VYR58_000432"
     CDS             77850..78599
                     /gene="truA"
                     /locus_tag="VYR58_000432"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV3621651.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            78589..79362
                     /locus_tag="VYR58_000433"
     CDS             78589..79362
                     /locus_tag="VYR58_000433"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV3621652.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            79340..79801
                     /locus_tag="VYR58_000434"
     CDS             79340..79801
                     /locus_tag="VYR58_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV3621653.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT        23753 a        14628 c        17937 g        23667 t
ORIGIN      
        1 tttagccaaa gagtctatta gtgctagaat aatagattag aattatttta gaaaaacgaa
       61 gtgagcagct tataaattca agtccccaaa tagattcata ctagtatctt ttgcaaaaaa
      121 taaagggcga cttccttcat gaatatcaat ttcatctata aggaaggtag ctaattgaac
      181 taacttattt attctgtttg tcgctagaaa aatcagacct ccttgtgaag attgaggaga
      241 tactgaatga aaatcaaaga agaaactagc aagctagcag cagattgcct aaaacaccgc
      301 tttgaggttg tagataagac tgacgtatat aatccaaggt gaagcgactg tggtttgaag
      361 agattttcaa agagtatagg ctagagagta gtgtttttat gtccttctag tagaaaatgc
      421 tagacagaag aatggggaac ttggatagga aaaatagatt gagaaaggag gttagaagag
      481 atgattatta caaaaattag ccgtttagga acttatgtgg gagtcaatcc acattttgca
      541 acattaatag attttctaga aaaaacagga ctagaaaatt taacagaagg ttcgattgct
      601 atcgacggta atcgattgtt tgggaattgc tttacttatc tagcagatgg tcaagcaggg
      661 gatttctttg aaacacacca aaaatatttg gatattcatt tagttttgga aaacgaagaa
      721 gccatggctg ttacatcgcc ggaaaatgta agcgttaccc aagaatatga tgaagagaaa
      781 gatattgaat tatacacagg gaaagtggaa cagttggttc atttgagagc tggcgaatgc
      841 ctcatcactt ttccagaaga tttacatcaa cccaaggttc gtataaatga tgaacctgtg
      901 aaaaaagttg tctttaaagt tgcgatttct taatgtagaa agagaagaac gatgaaaaaa
      961 atgagaaagt ttttatgtct agctggaatt gcgctagcgg ctgttgcctt ggtagcttgt
     1021 tcaggaaaaa aagaagctac aactagtact gaaccaccaa cagaattatc tggtgagatt
     1081 acaatgtggc actcctttac tcaaggaccc cgtttagaaa gtattcaaaa atcagcagat
     1141 gctttcatgc aaaagcatcc aaaaacgaaa atcaagattg aaacattttc ttggaatgac
     1201 ttctatacta aatggactac aggtttagca aatggaaatg tgccagatat cagtacagct
     1261 cttcctaacc aagtaatgga aatggtcaac tcagatgctt tggtgccgct aaatgattct
     1321 atcaagcgta ttggacaaga taaatttaac gaaactgcct taaatgaagc aaaaatcgga
     1381 gatgattact actctgttcc tctttattca catgcacaag tcatgtgggt tagaacagat
     1441 ttgttaaaag aacataatat tgaggttcct aaaacttggg atcaactcta tgaagcttct
     1501 aaaaaattga aagaagctgg agtttatggc ttgtctgttc cgtttggaac aaatgactta
     1561 atggcaacac gtttcttgaa cttctacgta cgtagtggtg gaggaagcct cttaacaaaa
     1621 gatcttaaag cagacttgac aagccaactt gctcaagatg gtattaaata ctgggttaaa
     1681 ttgtataaag aaatctcacc tcaagattct ttgaatttta atgtccttca acaagctacc
     1741 ttgttctatc aaggaaaaac agcatttgac tttaactctg gcttccatat cggaggaatt
     1801 aatgccaaca gtcctcaatt gattgattcg attgatgctt atcctattcc aaaaatcaaa
     1861 gagtctgata aagaccaagg aattgaaacc tcaaacattc caatggttgt ttggaaaaat
     1921 tcaaaacatc cagaagttgc taaagcattc ttagaagcac tttataatga agaagactac
     1981 gttaaattcc ttgattcaac tccagtaggt atgttgccaa ctattaaggg gattagcgat
     2041 tctgcagcct ataaagaaaa tgaaactcgt aagaagttta aacatgctga agaagtaatt
     2101 actgaagctg ttaaaaaagg tactgctatt ggttatgaaa atggaccaag tgtacaagct
     2161 ggtatgttga ctaaccaaca cattattgaa caaatgttcc aagatatcat tacaaatgga
     2221 acagatccta tgaaagcagc aaaagaagca gaaaaacaat taaacgattt atttgaggct
     2281 gttcagtaga tgtaaaagac tagaaaatag gtgggctagt gagctgaaaa gctctagccc
     2341 aattttgtaa aagaagggag aaggagaatg gttaaagaac gtaatttaac tcgctggata
     2401 tttgttttgc cagctatgat tatcgtagga ttactctttg tttatccgtt tttctcgagt
     2461 attttttata gctttaccaa taagcatttg attatgccta attataaatt tgttggtttg
     2521 gctaactata aagctgtgct atcagatccc aacttcttta atgcgttctt taattcaatt
     2581 aagtggacca ttttctcatt agttggtcaa gttttagtag ggtttgtatt ggctttagct
     2641 cttcacagag tacgccactt caagaaatta tataggacct tattgattgt tccttgggca
     2701 tttcctacca tcgttattgc cttctcttgg cagtggattc taaacggggt ttatggctac
     2761 ttacctaatc taatcgtaaa attaggttta atggaacata cacctgcatt tttgacagat
     2821 agtacatggg cattcctatg tttggtgttt atcaacattt ggtttggagc accaatgatt
     2881 atggttaatg tgctttcagc tttgcaaaca gtaccagaag aacaatttga ggctgctaag
     2941 atagatggtg cttcaagttg gcaggtgttc aagtttatcg tctttccaca tattaaagtg
     3001 gttgtaggac ttctagttgt tttgagaact gtatggatct ttaataactt tgacattatc
     3061 tacctcatta ctggaggtgg accagccaat gctacaacga cgcttccaat ttttgcttac
     3121 aacctgggtt ggggaactaa attgttgggt cgtgcttcag cagttacagt attgctcttt
     3181 atcttcttgg tggcgatttg ctttatctac tttgctatca tcagtaagtg ggaaaaggag
     3241 ggtagaaaat aatgaagaag aaatccagta tttatttaga tattctctca catgtacttt
     3301 tagttggtgc gaccatcgtt gcaattttcc cattggtatg gattatcata tcttctgtca
     3361 aagggaaagg ggaattaact cagtatccaa cacgattttg gcctgaacag tttacattag
     3421 attatttcac tcatgttatc aacgatttgc acttcattga taacattcga aacagtttaa
     3481 tcattgcctt ggctacaacc ctcattgcga ttattatttc tgctatggca gcctatggta
     3541 ttgttcgatt ctttcctaaa ttgggagcaa tcatgtcgag actactcgtc attacctaca
     3601 ttttcccacc aattttgtta gcaattccct attcaattgc cattgctaaa gttgggttaa
     3661 caaatagttt atttggcttg atgatggttt atctatcttt tagtgttcca tatgcagttt
     3721 ggctcttagt tggatttttc caaacagttc caattggaat tgaagaagcg gctagaattg
     3781 atggtgcaaa taaatttgtt acgttttata aagttgtgct accgattgta gcaccaggta
     3841 ttgtagcaac agctatttat acatttatca atgcttggaa tgaattcctg tatgccttga
     3901 ttttgattaa caatacagga aagatgacag tagcagtagc ccttcgttca cttaatggtt
     3961 cagaaatact agactgggga gatatgatgg cagcgtctgt tattgtagtt cttccatcaa
     4021 ttattttctt ctctatcatc caaaataaga ttgcaagtgg attatcagaa ggatctgtga
     4081 agtagacgaa agaaggaaaa aaatgaataa aagaggtctt tattcaaaac taggaatttc
     4141 tgttgtaggc attagtcttt taatgggagt ccccgctttg attcatgcga atgaattaaa
     4201 ctatggtcaa ctgtccatat ctcctatttt tcaaggaggt tcatatcaac tgaacaataa
     4261 gagtatagat atcagccctt tgttattaga taaattgtct ggagatagtc agacagtagt
     4321 aatgaaattt aaagcagata aaccaaactc tcttcaagct ttgtttggcc tatctaatag
     4381 taaagcaggc tttaaaaata attacttttc aattttcatg agagattctg gtgagatagg
     4441 tgtagaaata agagacgccc aaaagggaat aaattattta ttttctagac cagcttcatt
     4501 atggggaaag cataaaggac aggcagttga aaatacacta gtatttgtat ctgattctaa
     4561 agataaaaca tacacaatgt atgttaatgg aatagaagtg ttctctgaaa cagttgatac
     4621 atttttgcca atttcaaata taaatggtat agataaggca acactaggag ctgttaatcg
     4681 tgaaggtaag gaacattacc tcgcaaaagg aagtattgat gaaatcagtc tatttaacaa
     4741 agcaattagt gatcaggaag tttcaaatat tcccttgtca aatccatttc agttaatttt
     4801 ccaatcagga gattctactc aagctaacta ttttagaata ccgacactat atacattaag
     4861 tagtggaaga gttctatcaa gtattgatgc acgttatggt gggactcatg attctaaaag
     4921 taagattaat attgccactt cttatagtga tgataatggg aaaacgtgga gtgagccaat
     4981 ttttgctatg aagtttaatg actatgagga gcagttagtt tactggccac gagataataa
     5041 attaaagaat agtcaaatta gtggaagtgc ttcattcata gattcatcca ttgttgaaga
     5101 taaaaaatct gggaaaacga tattactagc tgatgttatg cctgcgggta ttggaaataa
     5161 taatgcaaat aaagccgact caggttttaa agaaataaat ggtcattatt atttaaaact
     5221 aaagaagaat ggagataacg atttccgtta tacagttaga gaaaatggtg tcgtttatga
     5281 tgaaacaact aataaaccta caaattatac tataaatgat aagtatgaag ttttggaggg
     5341 aggaaagtct ttaacagtcg aacaatattc ggttgatttt gatagtggct ctttaagaga
     5401 aaggcataat ggaaaacagg ttcctatgaa tgttttctac aaagattcgt tatttaaagt
     5461 gactcctact aattatatag caatgacaac tagtcagaat agagtagaga gttgggaaca
     5521 atttaagttg ttgcctccgt tcttaggaga aaaacataat ggaacttact tgtgtcctgg
     5581 acaaggttta gcattaaaat caagtaacag attgattttt gcaacatata ctagtggaga
     5641 actaacctat ctcatttctg atgatagtgg tcaaacatgg aagaaatcct cagcttcaat
     5701 tccgtttaaa aatgcaacag cagaagcaca aatggttgaa ctgagagatg gtgtgattag
     5761 aacattcttt agaaccacta caggtaagat agcttatatg actagtagag attctggaga
     5821 aacatggtcg gaagtttcgt atattgatgg aattcaacaa acttcatatg gcacacaagt
     5881 atctgcaatt aaatactctc aattaattga tggaaaagaa gcagtcattt tgagtacacc
     5941 aaattctaga agtggccgta agggaggcca attagttgtc ggtttggtca ataaagaaga
     6001 tgatagtatt gattggagat accactatga tattgatttg ccttcgtatg gttatgccta
     6061 ttctgcgatt acagaattgc caaatcatca cataggtgta ctgtttgaaa aatatgattc
     6121 gtggtcgaga aatgaattgc atttaagcaa tgtagttcag tatatagatt tggaaattaa
     6181 tgatttaaca aaataaagga gaaaaacatg gttaaatacg gtgttgttgg agcagggtat
     6241 tttggagctg aattggctcg ctatatgcaa aagaatgatg gagcagagat tactcttctc
     6301 tatgatccag ataatgcaga ggcgattgca gaagaattgg gagcaaaagt agcaagttcc
     6361 ttagatgagt tggtttctag cgatgaagta gattgtgtta tcgtcgcaac tccaaataat
     6421 cttcataagg aaccggttat taaggctgca cagcatggta aaaatgtttt ctgtgaaaaa
     6481 ccaattgcgc tttcttatca agattgtcgc gagatggtag atgcgtgtaa agaaaacaat
     6541 gtaaccttta tggcaggaca tattatgaat ttctttaatg gtgttcatca tgcaaaagaa
     6601 ctcattaatc aaggagttat cggagacgtt ctatattgtc atacagctcg taatggttgg
     6661 gaagaacaac aaccgtcagt atcatggaaa aaattcgtga aaaatcaggt ggtcacttgt
     6721 atcaccacat ccatgaattg gattgcgttc aattccttat ggggggcatg cctgaaactg
     6781 taaccatgac aggtggaaat gtggcccatg aaggtgaaca tttcggtgat gaagatgata
     6841 tgatttttgt caatatggaa ttttctaata agcgttttgc tttgttagaa tggggttcag
     6901 cttatcgttg gggtgaacat tatgtcttaa tccaaggaag caaaggtgcc atccgcttag
     6961 acttattcaa ctgtaaagga actcttaagc tagatgggca agaaagctat ttcttgattc
     7021 acgaatcgca agaagaagat gatgatcgga ctcgtatcta tcatagtaca gagatggatg
     7081 gagcaattgc ttatggtaaa ccaggtaaac gtactccatt atggctatca tctgtcattg
     7141 ataaagaaat gcgctatctg catgagatta tggaaggagc tccagtatca gaagaatttg
     7201 caaaactttt gacaggtgaa gctaccctag aagcaattgc tactgcagat gcttgtaccc
     7261 agtctatgtt tgaagatcgc aaagtaagat tgtcagaaat tgtaaaataa attttggtat
     7321 tctcctatct ataggtcgac ttgctcctct gaaagtactt ttagaggagc tgtttgactt
     7381 tgctagtttt tgaaactgaa atctattata ctacaaacta ttgaaagcgt tttaatttta
     7441 aggtataata atctcataga aataaagaaa aggaggaaag aggatgccac agattagcaa
     7501 agaagccttg attgagcaaa tcaaagatgg aatcatcgtt tcttgtcagg ctcttcctca
     7561 tgaaccgctt tatacagaag cgggaggggt gattcccttg ctggtcaaag cggctgagca
     7621 aggtggagca gtcggtatcc gagcaaacag tgttcgcgat atcaaggaaa ttaaggaagt
     7681 cactaaactt ccaatcattg ggattatcaa acgtgattat ccacctcagg aacccttcat
     7741 cacggctact atgaaagaag ttgatgaatt ggcagaactg gacatcgagg tgattgctct
     7801 ggattgtacc aagcgtgaac gctacgatgg tttggaaatt caagagttca ttcgtcaggt
     7861 taaggagaaa tatcctaatc agcttttgat ggctgatact agtatcttcg aagaagggct
     7921 agcagctgta gaagcaggaa ttgactttgt cggaacaacc ttatcaggct acacatccta
     7981 cagtccaaaa gtagacggtc cagattttga attgattaag aaactctgtg atgccggtgt
     8041 agatgtcatt gcagaaggaa aaattcatac accagaacaa gccaaacaaa tccttgaata
     8101 tggagtgcga ggcatcgttg ttggtggcgc cattactaga ccaaaagaga ttacagaacg
     8161 cttcgttgct agtcttaaat aagatgtgag agggagtttt atgtttaaag ttttacaaaa
     8221 agttggaaaa gcttttatgt tacctatagc tatacttcct gcagcaggtc tacttttggg
     8281 gattggtggt gcactttcaa acccaaccac gatagcaact tatccaatac tagacaatag
     8341 tatttttcaa tcaatattcc aagtaatgag ctctgcagga gaggttgtat tcagtaattt
     8401 gtcactactt ctctgtgtgg gattatgtat tggcttagcg aaacgagata aaggaaccgc
     8461 tgcgttagca ggagtaactg gttacttagt tatgactgca acgatcaaag ctttggtaaa
     8521 actttttatg gcagaaggat ctgcaattga tactggagtt attggagcat tagttgtcgg
     8581 aatagttgcc gtatatttgc acaaccgata taacaatatt caattacctt ccgctttagg
     8641 attctttgga ggttcacgct tcgttcctat tgttacatcg ttctcttcta tcttgattgg
     8701 ctttgtcttc tttgttattt ggccaccttt ccaacaactt cttgtttcta caggtggata
     8761 tatttctcag gcgggtccaa ttggaacttt tctatatgga tttttaatga gactttctgg
     8821 agcagtaggc ttacatcata taatttaccc tatgttttgg tatactgaac ttggtggtgt
     8881 tgaaactatt gcaggacaaa cagtggttgg agctcaaaaa atattttttg ctcaattagc
     8941 cgatccggcc cattctggat tatttacaga aggaacaagg ttttttgcag gtcgtttctc
     9001 aacaatgatg ttcggtttac cggctgcctg tttagcgatg taccatagtg ttcctaaaaa
     9061 tcgtcgtaaa aaatacgcgg gtttgttttt tggagttgct ttaacatctt ttattaccgg
     9121 tattacagaa ccaattgaat ttatgtttct attcgtcagt ccggttctat atgttgttca
     9181 cgcattcctt gatggtgtta gcttctttat tgcagacgtc ttaaatattt caataggaaa
     9241 cacattttca ggaggtgtaa tcgatttcac tttatttgga attttgcagg ggaacgctaa
     9301 gacgaattgg gttcttcaga ttccatttgg acttatttgg agtgttttgt attatattat
     9361 ttttagatgg ttcattactc aattcaacgt tctaacgcca gggcgaggag aagaagtaga
     9421 ttctaaagaa atttctgaat ccgcagattc aacttcaaat actgcagatt atttaaaaca
     9481 ggatagccta caaattatca gagccttggg tggatcaaat aatatagaag atgtagatgc
     9541 ttgtgtgaca cgtttacgtg tagctgtaaa agaagttaat caagttgata aagcactttt
     9601 aaaacaaatt ggtgcagttg atgtcttaga agtgaagggt ggcattcaag caatctatgg
     9661 agcaaaagca atcttatata aaaatagtat taatgaaatt ttaggtgtag atgattaagt
     9721 acttactgac ttaataaaaa acagaggaga gtgatggatg agtaggatga aatgaaatcg
     9781 catacaagaa ataaagaact cattatccaa gttggatacg cttattacat aggagaatac
     9841 aaatgaaatt tagaaaatta gcttgtacag tacttgcggg tgctgcggtt cttggtcttg
     9901 ctgcttgtgg caattctggc ggaagtaaag atgctgccaa atcaggtggt gacggtgcca
     9961 aaacagaaat cacttggtgg gcattcccag tatttaccca agaaaaaact ggtgacggtg
    10021 ttggaactta tgaaaaatca atcatcgaag cgtttgaaaa agcaaaccca gatataaaag
    10081 tgaaattgga aaccatcgac ttcaagtcag gtcctgaaaa aatcacaaca gccatcgaag
    10141 caggaacagc tccagacgta ctctttgatg caccaggacg tatcatccaa tacggtaaaa
    10201 acggtaaatt ggctgagttg aatgacctct tcacagatga atttgttaaa gatgtcaaca
    10261 atgaaaacat cgtacaagca agtaaagctg gagacaaggc ttatatgtat ccgattagtt
    10321 ctgccccatt ctacatggca atgaacaaga aaatgttaga agatgctgga gtagcaaacc
    10381 ttgtaaaaga aggttggaca actgatgatt ttgaaaaagt attgaaagca cttaaagaca
    10441 agggttacac accaggttca ttgttcagtt ctggtcaagg gggagaccaa ggaacacgtg
    10501 cctttatctc taacctttat agcggttctg taacagatga aaaagttagc aaatatacaa
    10561 ctgatgatcc taaattcgtc aaaggtcttg aaaaagcaac tagctggatt aaagacaatt
    10621 tgatcaataa tggttcacaa tttgacggtg gggcagatat ccaaaacttt gccaacggtc
    10681 aaacatctta cacaatcctt tgggcaccag ctcaaaatgg tatccaagct aaacttttag
    10741 aagcaagtaa ggtagaagtg gtagaagtac cattcccatc agacgaaggt aagccagctc
    10801 ttgagtacct tgtaaacggg tttgcagtat tcaacaataa agacgacaag aaagtcgctg
    10861 catctaagaa attcatccag tttatcgcag atgacaagga gtggggacct aaagacgtag
    10921 ttcgtacagg tgctttccca gtccgtactt catttggaaa actttatgaa gacaaacgca
    10981 tggaaacaat cagcggctgg actcaatact actcaccata ctacaacact attgatggat
    11041 ttgctgaaat gagaacactt tggttcccaa tgttgcaatc tgtatcaaat ggtgacgaaa
    11101 aaccagcaga tgctttgaaa gccttcactg aaaaagcgaa cgaaacaatc aaaaaagcta
    11161 tgaaacaata gtccttagtt attctataaa aagtagtttt ttaaagaacc taagagtgta
    11221 tacccccttt tccctctaca cagatagtgt aagaaaaggg ggcttttgtt taaaatgtaa
    11281 gaaactgtca cgaaattaaa atgaagttct tacataagcg aatcataaaa aatttcattt
    11341 tgattttaaa acagttcaag aaagtcaaaa aattattcta tttgaaagag aggtgccgac
    11401 tgtgaaagtc aataaaatcc gtatgcggga aacagtgatt tcctacgctt tcctagcacc
    11461 agtattattc ttctttgtca tctttgtgtt ggctccgatg gtgatgggct tcattacaag
    11521 tttctttaac tactcaatga ctaaatttga gtttgtaggc ttggataact atatccgtat
    11581 gtttaaagat cctgtcttta caaaatctct gattaacaca gttattttgg ttattggatc
    11641 tgtaccagtt gttgttctat tctcactctt tgtagcatct cagacctatc atcaaaatgt
    11701 cattgccaga tccttctacc gtttcgtctt cttccttcct gttgtaacgg gtagtgttgc
    11761 cgtgacagtt gtttggaaat ggatttatga cccactatca gggattctaa actttgtcct
    11821 taagtccagc cacatcatca gccaaaacat ttcttggttg ggagataaaa actgggcatt
    11881 gatggcgatt atgattattc tcttgaccac ttcagttggt cagcccatca tcctttatat
    11941 cgctgccatg gggaatattg acaattcact ggttgaagcg gcgcgtgttg atggtgcaac
    12001 tgagtttcaa gttttttgga agattaaatg gccaagcctt cttccaacaa ctctttatat
    12061 tgcaatcatc acaacaatta actcattcca gtgtttcgcc ttgattcagc ttttgacatc
    12121 tggtggtcca aactactcaa caagtacctt gatgtactac ctttacgaaa aagccttcca
    12181 attgacagaa tacggctatg ccaacacaat tggtgtcttc ttggcagtca tgattgctat
    12241 cgtaagcttt gttcaattta aagtacttgg aaacgacgta gaatactaaa gaaaggagac
    12301 agctatgcaa tctacagaaa aaaaaccatt aacagccttt actgttattt caacaatcat
    12361 tttgctcttg ttgactgtgc tgttcatctt tccattctac tggattttga caggggcatt
    12421 caaatcacaa cctgatacaa ttgttattcc tcctcagtgg ttccctaaaa tgccaaccat
    12481 ggaaaacttc caacaactca tggtgcagaa ccctgccttg caatggatgt ggaactcagt
    12541 atttatctca ttggtaacca tgttcttagt ttgtgcaacc tcatctctag caggttatgt
    12601 attggctaaa aaacgtttct atggtcaacg cattctattt gctatcttta tcgctgctat
    12661 ggcgcttcca aaacaagttg tccttgtacc attggtacgt atcgtcaact tcatgggaat
    12721 ccacgatact ctctgggcag ttatcttgcc tttgattgga tggccattcg gtgtcttcct
    12781 catgaaacag ttcagtgaaa atatccctac agagttgctt gaatcagcta aaatcgacgg
    12841 ttgtggtgag attcgtacct tctggagtgt agccttcccg attgtgaaac cagggtttgc
    12901 agcccttgca atctttacct tcatcaatac ttggaatgac tacttcatgc aattggtaat
    12961 gttgacttca cgtaacaatt tgaccatctc acttggggtt gcgaccatgc aggctgaaat
    13021 ggcaaccaac tatggtttga ttatggcagg agctgccctt gctgctgttc caatcgtcac
    13081 agtcttccta gtcttccaaa aatccttcac acagggtatt actatgggag cggtcaaagg
    13141 ataatactct gcgaaaatcg aatgcaaact acgtcagctt caccttgcca tacttaagta
    13201 ttgcctgcgg ttagcttcct agtttgttct tcaattttca ttgagtatag gaaaatcaat
    13261 ctatcaagat acagaagtat attttataga tttagagaat atagaggtta taagtgtcta
    13321 caaaatggag ggtatgcagt tactttatga agttttgtca gacgcttatc aacttaagaa
    13381 tggttttagt taactatcag aaacgaagga aagagtatga tttttgacga tttgaaaaac
    13441 atcacctttt acaaagggat tcatcccaat ttagacaagg ctatcgacta cctctaccaa
    13501 catcgtaaag attcattcga attaggaaag tatgagattg atggagataa agtctttcta
    13561 gttgttcagg aaaatgtcct caatcaagtt gagaataatc aatttgaaca ccataagaac
    13621 tatgcagatt tgcatttgct ggtagaagga catgaatatt cgagctacgg ttcacgtatc
    13681 aaagacgagg cagtagcatt cgacgaagcg actgacattg gctttgttca ttgtcatgaa
    13741 cactacccac tcttgttggg ttatcataat tttgcgattt tcttcccagg tgagccacat
    13801 cagccaactg gctatgcagg tatggaagaa aaggttcgaa aatatctctt taaaattttg
    13861 attgattaaa aataggatga attgtttttt tgtaaagctt tgacaatact ctaccatgaa
    13921 attgatcttt gtgaggtaga gaaatgagaa taaaatattt aaaaattggt atcttctaag
    13981 catgctgcaa gagctagttt cttagatgga caggggatta cagttgatga gatgtcctgg
    14041 ataattaatg gcattgtgaa tgcattgatt ggtagataca taaaattagg tacttatgca
    14101 gctaagtatg gtattagtat agcacgctcg atcttaagta gggcagctgc aactgcagca
    14161 gcaagagtag gattactgac caagatttct ggatggattt tacgagtagc tgtgaatgta
    14221 gctgatgtat atggtaattt tgccaacaat attgctgcag cttgggatgc atatgataaa
    14281 attcctaaca atggtcgtat aaacttttaa aatgcgagaa tgaaagcact ttgtattttt
    14341 ttattgaata tgttagcttg gacagtgctt gcaatgataa ttcgtggagg gctagatgga
    14401 tttgataggc atacttggag tactatttta attgcttcgc tgttcggggt atatgattat
    14461 aagcccatag ataaaaatag aaaaaagtcc aaaagaaaaa agaaaaaata gatttgttca
    14521 tggtagggac ttatgaaagc tttactgaca aaaaagaaaa cagtttacaa agaaaaatga
    14581 tggaggagca aacatggcac aaaaaggagt aagccttatc aaggcagcat ttgatacaga
    14641 taactttctc atgcgtttta gtgagaaggt cttggacatc gtgacagcca atcttctttt
    14701 tgtcgtctct tgtttgccca tcgtgacgat tggagtggct aaaatcagcc tctacgagac
    14761 catgttcgaa gttaagaaga gcagacgggt gcctgttttt aaaatctatc taagatcttt
    14821 caagcaaaat ctgaaactag gtcttcagtt aggtctgctt gagttgggca ttgtttcatt
    14881 aagcctccta gatctttatc tcttttgggg tcaaacagct ctgccctttc aattgctgaa
    14941 agctatttgt ctaggcattc tgattttcct tacgattgtg atgttggcta gctatccaat
    15001 cgcggcacgt tatgatttaa cttggaaaga aattcttcaa aaaggattga tgttggctag
    15061 ttttaacttt ccttggttct tcctcatgtt agccattctt gtcctcattg tgatggttct
    15121 ttatctgtct gccttcagtc tactcttagg tggctcagtc ttcctgcttt ttgggtttgg
    15181 actattggtc tttatccaga ctggattgat ggagaaaatt ttcgcaaaat accaatagga
    15241 gccttatttc tgaaactact ttcaaaggct ccaaacgcta ttctataagc gagaaactaa
    15301 aatctaagtg tctataagat attgaaagcc ttttcggtaa agtgtatact aaagaagtaa
    15361 agaaaaatct gctttagcag aaaataaaaa taataggaga aaatctatgt cagatttgaa
    15421 aaaatacgaa ggtgtcattc cagccttcta cgcatgttat gatgagcaag gagaagtaag
    15481 cccagaacgt acgcgtgcct tggttcaata cttcattgat aaaggtgttc aaggtcttta
    15541 tgtcaatggt tcttctggtg aatgtatcta ccaaagtgtt gaagaccgca agttaatctt
    15601 ggaagaagtt atggcagttg ccaaaggtaa attgaccatt attgcccatg ttgcttgcaa
    15661 taatactaaa gatagtatgg aacttgctcg ccatgctgaa agcttgggag tagatgctat
    15721 tgcaacgatt ccaccaattt atttccgctt gccagaatac tcagttgcca aatactggaa
    15781 cgatatcagt tctgcagctc caaacacaga ctacgtgatt tacaacattc ctcaattggc
    15841 aggggttgct ttgactccaa gcctttacac agaaatgttg aaaaatcctc gtgttatcgg
    15901 tgtgaagaac tcttctatgc cagttcaaga tatccaaacc tttgtcagcc ttggtggaga
    15961 agaccatatc gtctttaatg gtcctgatga gcagttccta ggaggacgcc tcatgggggc
    16021 tagggctggt atcggtggta cttatggtgc tatgccagaa ctcttcttga aactcaatca
    16081 gttgattgcg gataaggacc tagacacagc gcgtgaattg cagtatgcta tcaacgcaat
    16141 cattggtaaa ctcacttctg ctcatggaaa tatgtacggt gtcatcaaag aagtcttgaa
    16201 aatcaatgaa ggcttgaata ttggatctgt tcgttcacca ttgacaccag tgactgaaga
    16261 agatcgtcca gttgtagaag cggctgctgc cttgattcgt gaaaccaagg agcgcttcct
    16321 ctaatctaaa aggaggtatt tatgacatat tacgttgcaa ttgatatcgg tggaaccaac
    16381 atcaagtatg gtttggttga tcaagagggg caacttcttg aatcgcatga aatgccaact
    16441 gaggcgcata agggtggacc tcatatctta caaaagacca aagatatcgt agctagttat
    16501 ttagaaaaag gcccagtagc aggtgttgcc atatcttctg ctgggatggt ggatccggat
    16561 aagggtgaga ttttctatgc tgggccgcaa atccctaact acgcaggcac ccagttcaaa
    16621 aaggaaatcg aagaaagctt tactattcct tgtgagattg aaaatgatgt caactgtgca
    16681 ggtcttgctg aggcagtatc tggttcaggc aagggagcaa gtgtgacact ttgcttgacc
    16741 attggaacag gtatcggtgg ttgcttgatt atggatagga aagtcttcca tggttttagc
    16801 aattcagcct gtgaagtcgg gtatatgcat atgcaggatg gagcttttca agacttggct
    16861 tctacaacag ctttagtgaa atatgtagct gaagcccatg gagaagatgt tgatcagtgg
    16921 aatggccgta gaattttcaa agaagccact gaaggaaaca aaatctgcat ggaaggtatt
    16981 gaccgtatgg ttgactatct aggaaaaggt ctggcaaata tttgctatgt tgccaatcca
    17041 gaagtggtta ttcttggtgg tggtatcatg gggcaagagg ctatcctcaa acctaagatc
    17101 cgcacagcct tgaaagaggc tttggtacca agtttagcag aaaaaacacg attagaattt
    17161 gcccatcacc aaaatacagc agggatgttg ggtgcatatt atcattttaa gacaaaacaa
    17221 tcctagtttg gctcagccaa actaggattt tcttacacgt ttttgtctac gatagccgtt
    17281 gagtttttta ttttcccagt agctattaaa gattttttcc ttgctttcgc gattgatttc
    17341 caaaaagtag gcataaatca aatcgataaa gaagagcata ggaagttgag cggatattcg
    17401 ttggatatag gagggttggc tgtgggtggc tacaagaaca gtctctgtat aggtctggct
    17461 atctttattg ggaacacttg taaagagtac agtctttgcc cccatctcct tggcatctaa
    17521 tagactatct aaaatagaag gagttgagcc tgaaagtgag aagcccagta ctagacaatt
    17581 ttcatccatg atgctggttg tccaggcaaa gccgtcttgg tctgtcaaag cttcgcagac
    17641 cacacctagt cgcataaaac gtaatttcat ttcacgggcg acgaggccag aactccctgt
    17701 tccaaagaag tagatacgct cagcatcttc gattagctgg gcaattcgtt ctagttggat
    17761 ttcgtcaatc aagtcttgtg tttgttccct catattgcta taacttctga ggactcgttt
    17821 ggtcagtgga ctgtgcttgg agacttggtt ggcttgattt tctgcctgat gttggtattg
    17881 gaaaataaat tctcggtagc cagtaaagcc acacttttta gcaaagcggg tcaaagcagc
    17941 ttgagaaata tgtaattttt gggtgacttg ttgagaagat aaatcatctg taatcgtttc
    18001 agcttgcaaa aaatagcgag cgatttcttg ttctaggtct gtcatttctt caaaatgtga
    18061 atcaatgata gttgcgatat ctggtttgtc catagggaaa gctcctttac atgagtcata
    18121 ctggaagact agatcaggga atagtcacac ttcattataa cacataatat aaggatagat
    18181 aaataaaaac gcatctctgt tttaaaaacg aaaaaatcga aaaagcttct tacttttcca
    18241 taattttcta ctcaaattgt ggtacaatta agagtaagat tttaagttag aaatgagact
    18301 gatttgtatg agaaaattta acagccattc gattccgatt cggcttaatt tattgttttc
    18361 aatcgtcatt ttactcttta tgaccattat tggtcgtttg ttgtatatgc aggttttgaa
    18421 caaggatttt tacgaaaaaa agctagcctc agctagtcag accaaggtca caaccagttc
    18481 tgctcgtggg gaaatttatg atgctagtgg aaaacctttg gtagaaaata cgttaaaaca
    18541 ggttgtttcc tttacgcgta gcaataaaat gacggctaca gacttaaaag aaacagctaa
    18601 aaagttactg acttatgtga gcatcagttc gccaaatttg acagaacgcc agctggctga
    18661 ttactatttg gctgatcctg aaatctataa aaaaacagtg gaagctctcc caagtgagaa
    18721 acgcttggat tcagatggta atcgcctatc cgaatcagaa ctgtataaca atgcggtcga
    18781 tagtgtccca acaagtcaac taaactatac agaggatgaa aagaaagaaa tctatctttt
    18841 tagtcagtta aatgctgttg gaaactttgc gacaggaacc attgcgacag atcctctaaa
    18901 tgattctcag gtggctgtta ttgcctctat ttcaaaggag atgcctggca ttagtatttc
    18961 tacttcttgg gatcgaaagg ttttggaaac ttccctttct tctatagtag ggagtgtatc
    19021 cagtgaaaaa gctggtctcc cagcggaaga agcagaagcc tatcttaaaa aaggctattc
    19081 tctaaatgac cgtgttggaa cctcctattt ggaaaagcaa tatgaagaga ccttacaagg
    19141 gaaacgctcg gtaaaagaaa tccatctgga taaatatggc aatatggaaa gtgtggatac
    19201 aattgaggaa ggtagtaagg gaaacaatat caaactgacc attgatttgg ccttccaaga
    19261 tagcgtggat gctttgctga aaagttattt caattcagag ttgggaaatg gtggagccaa
    19321 gtattctgaa ggtgtctatg cagtcgccct taacccaaaa acaggtgctg ttttgtctat
    19381 gtcagggatt aaacatgact tgaaaacggg agagttgacg ccggattcct tgggaacggt
    19441 aaccaatgtc tttgttccag gttcggttgt caaggcggcg accatcagct caggctggga
    19501 aaatggagtc ttgtcaggaa atcagacctt gacagaccag tccattgtct tccaaggttc
    19561 agctccaatt aattcttggt atactgcctt ttctaggcca atgccgatta cggcagttca
    19621 ggctctagag tattcatcca atgcttatat ggtccaaaca gccttaggtc ttatggggca
    19681 aacctatcaa ccaaatatgt ttgtcggcac cagcaatcta gagtctgcta tgggtaaatt
    19741 gcgttcaacc tttggcgaat atggcttggg ttctgcgaca ggaattgacc taccagatga
    19801 atctactgga tttattccca aagagtatag ctttgctaat tacattacta atgcctttgg
    19861 gcagtttgat aactataccc caatgcaatt ggctcagtat gtggcaacta ttgcaaatga
    19921 tggtgttcgt gtggctcctc gtattgttga aggcatttat ggtaataatg ataagggagg
    19981 actgggcgac ttgattcagc aactgcaacc gacagagatg aataaggtca atatatccga
    20041 ctccgatatg agtgtcttgc accaaggttt ttatcaggtt gctcatggga ctagcggatt
    20101 gacaactgga cgtgcctttt caaatggtgc cttggtatcc attagcggaa aaacgggtac
    20161 agccgaaagc tatgtggcag atggtcagca agcaaccaat accaatgcgg tggcctatgc
    20221 cccatctgat aatccccaaa tcgctgttgc agtggtcttt cctcataata ccaatctaac
    20281 aaatggtgta gggccttcca ttgcgcgtga cattatcaat ctgtatcaaa aataccatcc
    20341 gatgaactag aaaggaaatt atgctttatc caacacctat tgccaagttg attgacagtt
    20401 attctaagtt accaggtatc gggattaaga cggctacgcg tctggccttt tatacgattg
    20461 ggatgtctgc tgatgatgtc aatgaatttg caaaaaatct cctttctgct aagagagaat
    20521 tgacatattg ttctatttgt ggacgtttga cagacgacga tccttgttct atctgtactg
    20581 atccgactcg tgaccagaca acaattttag ttcttgagga tagtagagat gtggcagcca
    20641 tggaaaatat ccaagaatac catggactct atcatgtcct gcatggcctc atttctccta
    20701 tgaatggtat cagtccggac gatatcaatc tcaagagcct tatgactcgt cttatggata
    20761 gtgaggtttc agaagtgatt gtggcgacta atgctacagc ggatggtgaa gcgacttcca
    20821 tgtatctttc acgtttgctc aagccggttg gtatcaaggt tacgcgtcta gcacgaggtc
    20881 tcgctgtggg agcggacatt gagtatgcgg acgaagtgac actcttacga gcgattgaaa
    20941 atcggacaga gttgtaagtg taggcaaatt tacgaactcc cttcatttat aaaaaatcaa
    21001 agaggctgaa aatcgttcct atcggcctct ttttgtatag tgtgatgagt aggatcgggt
    21061 tcaagtttta aaaaaccaag caaatatgat atactaaaga gcgagtattc tagtagaatt
    21121 aggacaaata atatgaaaca aacgattatt cttttatatg gtggacggag tgcggaacgc
    21181 gaagtctctg tcctttcagc tgagagtgtc atgcgtgcgg tcaattacga ccgtttcaca
    21241 gtcaagactt tctttatcag tcagtcaggt gactttatca aaacacagga atttagtcat
    21301 gctccggggc aagaagaccg tctcatgacc aatgaaacca ttgattggga taagaaagtt
    21361 gcaccaagtg ctatctacga agaaggtgca gtggtctttc cagtccttca cgggccaatg
    21421 ggagaagatg gctctgttca aggattcttg gaagttttga aaatgcctta cgttggttgc
    21481 aacattttgt catcaagtct tgccatggat aaaatcacga ctaagcgtgt tctggaatct
    21541 gctggtattg cccaagttcc ttatgtggct atcgttgaag gcgatgatgt gactgctaaa
    21601 atcgctgaag tggaagaaaa attggcttat ccagtcttca ctaagccgtc aaacatgggg
    21661 tctagtgtcg gtatttctaa gtctgaaaac caagaagaac tccgtcaagc cttaaaactt
    21721 gccttccgat atgacagccg tgtcttggtt gagcaaggag tgaatgcccg tgaaattgag
    21781 gttggcctct tgggtaacta cgatgtcaag agcacgctac ctggagaagt tgtcaaggac
    21841 gttgcctttt atgactacga tgccaagtat attgataaca agattactat ggatattcct
    21901 gccaaaatca gtgatgatgt ggtggctgtc atgcgtcaaa atgcagaaac agccttccgt
    21961 gccattggtg gccttggtct atctcgttgc gatttcttct atacagataa gggagagatt
    22021 tttctcaacg agctcaatac catgccaggt ttcacccagt ggtctatgta cccactactt
    22081 tgggacaata tggggatcag ctacccagaa ctaatcgagc gtttggttga ccttgccaag
    22141 gaaagttttg acaagcgcga agcgcatttg atataaaatg aaagagaggg tagaagccag
    22201 aaccatcact gcaaggtgac tagagttctc ggacttcagc cctttttaaa ggagtagaaa
    22261 tgaaattaac aatccatgaa attgcccaag ttgttggagc caaaaatgat atcagtatct
    22321 ttgaggacac ccagttagaa aaagctgagt ttgatagtcg tttgattgga actggagatt
    22381 tatttgtgcc acttaaaggt gcgcgtgacg gtcatgactt tatcgaaaga gcttttgaaa
    22441 atggtgcggc agcaaccctg tctgagaaag aggttgcaaa tcatccctac attctagtag
    22501 atgatgtttt gactgccttt caacaactag ctgcctacta tcttgaaaaa acagctgttg
    22561 atgtctttgc ggttacgggt tcaaatggca agacaacgac taaggatatg ttggcgcatt
    22621 tactgtcaac gacctacaag acctacaaaa cacaaggcaa ctacaataac gagattggcc
    22681 ttccctacac agttctacac atgcctgaag gaacagaaaa gttggttttg gagatggggc
    22741 aggaccactt gggcgatatt catctcttgt ctgaattggc tcgtccaaaa acagccatcg
    22801 tgaccttggt tggagaagct catttagcct ttttcaaaga tcgttctgag attgctaaag
    22861 gaaaaatgca aattgcagac ggaatggctt caggttcctt gcttttagcg ccggctgacc
    22921 ctatcgtaga ggactatttg ccaactgata aaaaggtggt tcgttttggg caaggggtag
    22981 agctggaaat tactgacttg gttgagcgca aagatagtct gaccttcaag gccaatttct
    23041 tagagcaagt ccttgatttg ccagtaactg gcaagtacaa tgcgacaaat gctatgattg
    23101 catcctatgt tgccttgcaa gaaggagttt cagaggagca aattcgtttg gccttccaag
    23161 atcttgaatt gacgcgtaac cgtaccgagt ggaagaaagc agccaatgga gcagatatcc
    23221 tgtcagatgt ttacaatgcc aatccaactg ctatgaaact gattttagag actttctctg
    23281 ccattccagc caatgaaggt ggcaagaaaa ttgcagtttt ggcggatatg aaggagcttg
    23341 gtgaccagtc tgttcaactt cataatcaga tgattttgag cctctcccca gatgtgcttg
    23401 atatcgttat tttctatgga gaagacattg ctgaattagc ccaattggcc agtcaaatgt
    23461 tcccaattgg ccacgtttac tacttcaaga aaacagaaga ccaagaccaa tttgaagact
    23521 tagtcaagca ggtcaaggaa agcctcagtg ccaatgatca aatcttgctc aagggctcta
    23581 actctatgaa cctagccatg ttggtagaaa gtttagaaaa tgaaaccaag tgattttgtt
    23641 aagtatctgt aaagaatgat tgcccttaca gatactggct taacctttac aaaagagcct
    23701 tttgaccgtg agcgctacga agacttgcga agtctgttat ctgaaatgtt gaatcaggta
    23761 tcagaccttg atgcagacga agtggcagaa ctcttgaaac cgacctccgc ttatgcgact
    23821 cccttaatgg acgtccgtgc ttggattgtt gaggatgaga agatttgtct ggttagggga
    23881 caaggagagg atagttgggc tttgccaggt ggctttggtg aagtcggcta ttctccaact
    23941 gaaaatattc tcaaggaaat tgaagaagaa accggtttta aagccaaagt tgaaagactg
    24001 ctagctgttt ttgataccaa tcgtttccaa ctacagagca aacaatatgc aaagtttgtt
    24061 tttgaatgta agcttctcga tggacaattc caagaaaatc aagaaatcgc tgaccttcaa
    24121 ttttttgcaa ttgaccaact gccgaattta tctgaaaaac gcattaccaa ggagcaaatc
    24181 gagattcttt ggcaggttta tcaaggtcag agggagcaat atcttgacta agaagatgat
    24241 tatcgtattt ctaaattcat ttttcttaag tagcatggta taataaaatg caggaaaatt
    24301 ttgaatcatg aggaagacta gatgaattta tgggatattt tctttacgac tcaggcaacc
    24361 gagccgccca aatttgacct tttttggtat gttagcctat ttacgctctt agccttaacc
    24421 ttttatacag cccatcgcta tcgtgaaaag aaggtttacc aacgattttt ccaaatcttg
    24481 cagactgttc agttaatcct tctttatggt tggtactggg tcaatcatat gccactgtca
    24541 gaaagcctac ccttttacca ttgccgtatg gctatgtttg tggtactctt gcttcctggt
    24601 cagtccaaat ataaacaata ctttgcatta ttgggaacat ttgggacatt agcagccttt
    24661 gtttatccag tgccagatgc ttaccctttt ccacatatca ccattctatc ctttatcttt
    24721 ggtcatttag cactcttggg gaactctcta gtttatctat tgagacagta taatgcgcga
    24781 ttgctggatg tgaagggaat ttttctcatg acctttgccc taaatgcctt gatttttgtg
    24841 gtcaatttgg tgacaggtgg cgattacgga tttttgacaa aaccgccatt ggttggggat
    24901 cacggtctag tagctaatta tttacttgtt tcaattgtgc tggtagctac tatcagtttg
    24961 actaagaaaa tcttagaatt ctttttagct caagaagcag aaaaaatgat tgcaaaggaa
    25021 gcttaacaca gagctttctt ttttgctctt agagagtttt tacaagcagc ttataaaata
    25081 agaatttctg aatagacaaa ctcaaaaaat ggctgggaaa tttaggaaaa aagcaagcac
    25141 gattaaattt tttgtgttat aatattttgt gaatagctat gcctatgttt agctatggaa
    25201 taatacgaag tgcgaaactt ggaagataga gaggaagcga tgtaatggct agagaaggct
    25261 tttttacagg tctagatatt ggaacaagct ctgtcaaggt gcttgtggcc gagcagagaa
    25321 atggtgaatt aaatgtaatt ggcgtgagta atgccaaaag taaaggtgta aaggatggaa
    25381 ttattgttga tattgatgca gcagcaactg ctatcaagtc agccatttcc caagcggaag
    25441 aaaaggcagg catttcgatt aaatcagtaa atgtcggctt gcctggtaat cttttgcagg
    25501 tagaaccaac tcaggggatg attccagtaa catctgatac taaggaaatt acggatcaag
    25561 atgttgaaaa tgttgtcaaa tcagctttga caaagagtat gacacctgac cgtgaagtca
    25621 ttacctttat tcctgaagaa tttattgtgg atggtttcca agggattcgt gacccacgtg
    25681 gcatgatggg ggttcgcctt gaaatgcgtg gtttgcttta tacaggacct cgtactatct
    25741 tgcacaattt gcgtaagacg gttgagcgtg caggtgttca ggttgaaaat gttatcattt
    25801 caccactagc aatggttcag tctgttttga acgaagggga acgtgaattt ggtgctacag
    25861 tgattgatat gggggcaggt caaacgactg tcgctacaat ccgtaatcaa gaactccagt
    25921 tcacacatat tctccaagaa ggtggagatt atgtaactaa agatatctcc aaggttttga
    25981 aaacctctcg caaattagcg gaaggcttga aactgaatta cggggaagcc tatccgcctc
    26041 ttgcaagcaa agaaaccttc caagtagagg ttattggaga agtagaagca gtcgaagtga
    26101 cggaagccta cttgtcagaa attatttctg cacgaatcaa gcacatcctt gaacaaatca
    26161 agcaagaatt agatagaagg cgtctattgg acctccctgg tggtattgtc ttaatcggtg
    26221 ggaatgccat tttaccaggt atggttgagc ttgctcagga agtctttggc gtccgtgtca
    26281 agctttatgt tccaaatcaa gttggtatcc gtaatccagc ctttgcgcat gtgattagtt
    26341 tatcagaatt tgcgggtcaa ttaacagaag ttaatctttt ggctcaggga gcgataaaag
    26401 gtgagaatga cttaagtcat cagccaatta gttttggtgg gatgctgcaa aaaacagctc
    26461 agtttgtaca atcaacgcct gttcaaccag ctcctgctcc agaagtagag ccggtggcgc
    26521 ctacagaacc aatggcggat ttccaacaag cttcacaaaa taaaccgaaa ttagcagatc
    26581 gtttccgtgg attgatcgga agcatgtttg acgaataaag aggaaaaata aattatgaca
    26641 ttttcatttg atacagctgc tgctcaaggg gcagtgatta aagtaattgg tgtcggtgga
    26701 ggtggtggca atgccatcaa ccgtatggtc gacgaaggtg ttacaggcgt agaatttatc
    26761 gcagcaaaca cagatgtaca agcattgagt agtacaaaag ctgagactgt tattcagttg
    26821 ggacctaaat tgactcgtgg tttgggtgca ggaggtcaac ctgaggttgg tcgtaaagcc
    26881 gctgaagaaa gcgaagaaac actgacggaa gctattagtg gtgccgatat ggtcttcatc
    26941 actgctggta tgggaggagg ctctggaact ggagctgctc ctgttattgc tcgtatcgcc
    27001 aaagatttag gtgcgcttac agttggtgtt gtaacacgtc cctttggttt tgaaggaagt
    27061 aagcgtggac aatttgctgt agaaggaatc aatcaacttc gtgagcatgt agacactcta
    27121 ttgattatct caaacaacaa tttgcttgaa attgttgata agaaaacacc gcttttggag
    27181 gctcttagcg aagcggataa cgttcttcgt caaggtgttc aagggattac cgatttgatt
    27241 accaatccag gattgattaa ccttgacttt gccgatgtga aaacggtaat ggcaaacaaa
    27301 gggaatgctc ttatgggtat tggtatcggt agtggagaag aacgtgtggt agaagcggca
    27361 cgtaaggcaa tctattcacc acttcttgaa acaactattg acggtgctga ggatgttatc
    27421 gtcaacgtta ctggtggtct tgacttaacc ttgattgagg cagaagaggc ttcacaaatt
    27481 gtgaaccagg cagcaggtca aggagtgaac atctggctcg gtacttcaat tgatgaaagt
    27541 atgcgtgatg aaattcgtgt aacagttgtc gcaacgggtg ttcgtcaaga ccgcgtagaa
    27601 aaggttgtgg ctccacaagc tagatctgct actaactacc gtgagacagt gaaaccagct
    27661 cattcacatg gctttgatcg tcattttgat atggcagaaa cagttgaatt gccaaaacaa
    27721 aatccacgtc gtttggaacc aactcaggca tctgcttttg gtgattggga tcttcgccgt
    27781 gaatcgattg ttcgtacaac agattcagtc gtttctccag tcgagcgctt tgaagcccca
    27841 atttcacaag atgaagatga attggataca cctccatttt tcaaaaatcg ttaagtaaat
    27901 gaatgtaaaa gaaaatacag aacttgtttt tcgagaagtt gcagaggcta gtctgagtgc
    27961 tcatcgagag agtggttcgg tctctgtcat tgcagttacc aagtatgtag atgtaccgac
    28021 agcggaagcc ttgcttccgc taggtgttca tcatatcggt gaaaatcgtg tagataagtt
    28081 tctggaaaaa tatgaagctt taaaagatcg agatgtgact tggcatttga ttggtacctt
    28141 gcaaagacgt aaggtgaaag atgtcattca atacgttgat tatttccatg cattggactc
    28201 agtaaagcta gcaggggaaa ttcaaaaaag aagtgaccga gtcatcaagt gtttccttca
    28261 agtaaatatt tctaaagaag aaagcaaaca cggtttttcg agagaggaac tgctggaaat
    28321 cttgccagag ttagccagac tagataagat tgaatatgtt ggtttaatga cgatggcacc
    28381 ttttgaggct agcagtgagc agttgaaaga gattttcaag gcggcccaag atttacaaag
    28441 agaaattcaa gagaaacaaa ttccaaatat gcctatgacc gagttaagta tgggaatgag
    28501 tcgtgattat aaagaagcga ttcaattcgg ttccactttt gttcgtatag gtacatcatt
    28561 ttttaagtag gagagaacca tgtctttaaa agatagattc gatagattta tagattattt
    28621 tacggaggat gaggattcaa gtctccctta tgaaaaaaga gatgagcctg tgtttactcc
    28681 agtaaattct tcacaggaac cggctctccc aatgaatcaa ccttcacagt cggctggtac
    28741 aaaagagaac aatatcacca gacttcatgc aagacaacag gaattggcaa atcagagtca
    28801 gcgtgcaacg gataaggtca ttatagatgt tcgttatcct agaaaatatg aggatgcaac
    28861 agaaattgtt gatttattgg caggaaacga aagtatcttg attgattttc agtatatgac
    28921 agaggtgcag gctcgtcgtt gtttggacta tttggatgga gcttgtcatg ttttagctgg
    28981 aaatttgaaa aaggtagctt ctaccatgta tttgttgaca ccagttaatg ttattgtaaa
    29041 tgttgaagat atccgtttac cagatgaaga tcaacagggt gagttcggtt ttgatatgaa
    29101 gcgaaataga gtacgataat gattttttta attcgtatga tttataatgc agtggatatt
    29161 tactccctga ttttggtagc cttcgctgtc atgtcttggt ttccaggtgc ctacgaatcc
    29221 agtttaggtc gttggattgt agcgttggtg aaaccagtac ttgctccctt gcaacgcctg
    29281 cctttacaga tagcgggtct tgatttatct gtttgggtcg cgattgtttt ggttcgattt
    29341 ttaggagaaa acctagtgcg ttttctggcg atgataggat gaataaaggg atttatcagc
    29401 atttctccat agaagatcgt ccatttcttg acaagggaat ggaatggata aagaaggtag
    29461 aagatagcta tgctcctttt ttaactcctt ttatcaatcc tcatcaggag aagctattaa
    29521 agattttggc caaaacctat ggtcttgctt gtagcagtag tggggaattc gtctcgagtg
    29581 agtatgttcg agttttatta tacccagatt atttccaacc agagttttca gattttgaaa
    29641 tatctctcca agaaattgtg tattccaata aatttgaaca tttaacgcat gctaagattt
    29701 tagggacagt catcaatcaa ttagggattg aacggaaact ttttggagat atcctagtag
    29761 atgaagaacg ggcgcagatt atgattaatc agcagtttct tcttctcttt caagatggac
    29821 taaagaaaat tggtcgtata cctgtttcgc tggaggaacg tcctttcacc gagaaaatag
    29881 ataagctaga acagtatcga gaactggatt tatctgtgtc tagttttcga ttagatgttc
    29941 ttttatcaaa tgttttgaaa ctatctagga atcaagcaaa ccagttgatt gaaaagaaac
    30001 ttgtccaagt aaattatcat gtggtagaca aatcagatta cactgttcaa gttggagact
    30061 tgattagtgt gagaaaattt ggtcgcttga gattacttca agataaggga caaacgaaaa
    30121 aagagaagaa aaaaataacc gtccagttat tattaagtaa gtgaggaata gaatgccaat
    30181 tacatcatta gaaataaagg acaagacttt tggaactcga ttcagaggtt ttgatccaga
    30241 agaagtcgat gaatttttag atattgtggt tcgtgattac gaagatcttg tgcgtgcgaa
    30301 tcatgataaa aatttgcgta ttaagagttt agaagagcgt ttgtcttact ttgatgaaat
    30361 aaaagattca ttgagccagt ctgtattgat tgctcaggat acagctgaga gagtgaaaca
    30421 ggcggcgcat gaacgttcaa acaatatcat tcatcaagca gagcaagatg cgcaacgctt
    30481 gttggaagaa gctaaatata aggcaaacga gattcttcgt caagcaactg ataatgctaa
    30541 gaaagtcgct gttgaaacag aagaattgaa gaacaagagc cgtgtcttcc accaacgtct
    30601 caaatctaca attgagagtc agttggctat tgttgaatct tcagattggg aagatattct
    30661 ccgtccaaca gctacttatc ttcaaactag tgatgaagcc tttaaagaag tggttagcga
    30721 agtacttgga gaaccgattc cagctccaat tgaagaagaa ccaattgata tgacacgtca
    30781 gttctctcaa gcagaaatgg aagaattaca agctcgtatt gaggtagccg ataaagaatt
    30841 gtctgaattt gaagctcaga ttaaacagga agtggaaact ccaactcctg tagtgagtcc
    30901 tcaagttgaa gaagagcctc tgctcatcca gttggcccaa tgtatgaaga accagaagta
    30961 gctccagtgc atccgacagg tccaacacca gctacagaaa ctgttgattc agcaccagga
    31021 tttgaagcac cgcaagaatc cgttacaatt ttataagaaa cgatgtgaga acaatatctt
    31081 atccttatat ttccagcgag caggagatgg tgtgagtcct gcattcccta acgataagat
    31141 tatcctctca aaaactcaag tctgaagcta gtaagatttg acgtttccca cgttacggga
    31201 taagagggag aaagactaaa tctttttccg aataaaggtg gtaccacgat tttcgtcctt
    31261 tttggaagtc gtggttttta atttgttatt atttataaag gagataccat gaaactcaaa
    31321 gataccctta atcttgggaa aacagctttc ccaatgcgtg caggccttcc gaccaaagag
    31381 ccagtttggc aaaaggaatg ggaagatgca aaactttacc aacgtcgtca agaactaaat
    31441 gaagggaaac cgcattttgt cttgcatgat ggccctccat acgcaaacgg aaatatccac
    31501 gttggacatg ccatgaatca tatctcaaaa gatatcatca ttcgttctaa gtctatgtca
    31561 ggttttaacg caccttatat cccaggttgg gatactcatg gtctgccaat cgagcaagtt
    31621 ttggcaaagc aaggtgtgaa gcgcaaagaa atggacttgg ttgagtactt gaaactctgt
    31681 cgtgagtacg ctctttctca agtttataaa caacgtgatg atttcaaacg cttggggatg
    31741 tcaggtgact gggaaaattt atatgtgact ttaactccag actatgaagc agcccaaatc
    31801 cgtgtctttg gtgagatggc taataagggt tatatctacc gtggtgccaa gccagtttac
    31861 tggtcatggt catctgagtc agcccttgcc gaagcggaaa ttgaatacca tgatttggtt
    31921 tcgacttcac tttattatgc caataaggta aaagatggca aaggtatcct agatacagat
    31981 acttatatcg tagtctggac aacaactcca tttaccatca cagcttctcg tggtttgact
    32041 gttggtgcag atattgatta cgttttggtt caacctgcta gtgaaactcg taagtttgtc
    32101 gttgctgcag aattgttgac tagcttgtct gagaaatttg gctgggctga tgttcaagtg
    32161 ttggcaactt accgtggtca agaactcaac cacatcgtaa cagaacaccc atgggataca
    32221 gctgtagatg agttggtaat ccttggtgat cacgttacca ctgactctgg tacaggtatc
    32281 gtccatacag cccctggttt tggtgaggac gactacaatg ttggtattgc taatggtctt
    32341 gaagtcgcag tgactgttga cgaacgcggt atcatgatgg cgaatgctgg tcctgagttt
    32401 gaaggtcagt tctacgacaa ggttgtacca actgttattg aaaaacttgg taacctcctt
    32461 ctagcccaag aagaaatctc tcactcatac ccatttgact ggcgtactaa gaaaccaatc
    32521 atctggcgtg cagttccaca atggtttgcc tcagtttcaa aattccgcca agaaatcttg
    32581 gatgctattg ataaagttaa attccataca gaatggggta aagtacgtct atataatatg
    32641 attcgtgacc gtggtgactg ggttatctct cgtcaacgtg cttggggtgt tccacttcca
    32701 atcttctatg cagaagacgg tacagctatc atgacagctg agactattga acatgtggcg
    32761 caactctttg aagtacatgg ttcaagcatt tggtgggaac gtgatgccaa agacctctta
    32821 ccagaaggat ttacacatcc aggttctcca aatggggagt tcaagaaaga aacagatatt
    32881 atggatgtat ggtttgactc aggttcatca tggaatggtg ttttggtaaa tcgtccaaat
    32941 ctgacttatc cagctgacct ttaccttgaa ggttctgacc aataccgtgg ttggttcaac
    33001 tcatcactca ttacatctgt tgccaaccat ggcgtagcac cttacaaaca aatcttgtca
    33061 caaggtttta cccttgatgg taaaggtgag aagatgtcta aatcacttgg aaataccatt
    33121 gctccaagtg atgttgaaaa acaatttggt gcagaaatct tgcgtctctg ggtaacaagt
    33181 gttgactcaa gcaatgacgt gcgtatctct atggatattt tgagccaagt ttctgaaact
    33241 taccgtaaga ttcgtaacac tcttcgtttc ttgattgcca atacatctga ctttaaccca
    33301 gctcaagatg tagtcgctta cgatgaactt cgttcagttg ataagtacat gactattcgc
    33361 tttaaccagc ttgtcaagac cattcgtgat gcctatgcgg actttgaatt cttgacaatc
    33421 tacaaggcct tggtgaactt tatcaacgtt gacttgtcag ccttctacct tgattttgcc
    33481 aaagatgttg tttacattga aggtgccaaa tcattggaac gccgtcaaat gcagactgtt
    33541 ttctatgaca ttcttgtcaa aatcaccaaa ctcttgacac caatccttcc tcacactgcg
    33601 gaagaaatct ggtcatatct tgagtttgaa gctgaagact tcgttcaatt gtcagaattg
    33661 ccagaagctc aaacttttgc taatcaagaa gaagtcttgg atacatgggc agccttcatg
    33721 gacttccgtg gacaagctca aaaagccttg gaagaagctc gtaatgcaaa agttatcggg
    33781 aaatcgcttg aagcacactt gacagtttat ccaaatgaag ttgtgaaaac tctactcgaa
    33841 gcagtaaaca gcaatgtggc tcaacttttg atcgtgtcag acttgaccat cgcagaaggg
    33901 ccagctccag aagctgccct tagcttcgaa gatgtagcct tcacagttga acgcgctgca
    33961 ggtcaagtat gtgaccgttg ccgtcgtatc gacccaacaa cagcagaacg cagctaccag
    34021 gcagtcatct gtgaccactg tgcaagcatc gtagaagaaa actttgcgga agcagtcgca
    34081 gaaggatttg aagagaaata aggttgaaaa gtctaggcaa aattcaattt gagaagaaaa
    34141 gacaactaat tttatagtct attaaacgca ttgtatcacg tttttgaata cctgatatga
    34201 tgcgtttttt atttatttta aaaatttgcg aggtatgact ttttatactc aacaagaatc
    34261 aaagagaaac ttagcaagct aacagtagta agataaaata ggaatttgat attagggata
    34321 agattgctaa atagtgtaat atttttacaa taataaattt atatagttat ttttggtttc
    34381 tgaaaagtat tatattttat ttcatattat acaaattttt attttataat atcagaaaat
    34441 acttttttta aaagcaaata tgatacaatt ttatttgaaa aaaataaaaa aggagatttt
    34501 attatgaaat taaaaacact tgctttaatt agtggtatcg tcggtcttgt gggaggaatt
    34561 ttacttctta ttggtccttt tgtcttgttg ggaacagcgg taaacacagt tgctacaact
    34621 cttaatggag gagctactgc aggggctttt tcaggtgttg ccttactctt gaatgccttg
    34681 aagattgcaa atcttgttct tggtatcatt gctattgttt actataaagg agataatcgt
    34741 gtaggtgcag ctccgtctgt actaatgatt gtttttggtg gagttagtct cattccattc
    34801 ttaggatggg ttggggggat tcttgttatt atcggaggat ctctattcct tgcaacattg
    34861 aagaaattca aatcagaaga ataaaaggta ttttagcatg aaaagaacaa aaaagtttat
    34921 cggtatagga gtagctctat tatctctttt tcttctagtt gcatgtggaa cataaagttc
    34981 aaaggatact tcaacaagta atgatgagaa gacagtagca acatccaata gttcaaaaga
    35041 aacaatcact ttcgatacac cggttgtaac agacgatgtg attgaatcaa tacgcactta
    35101 tgcagattat atagatcttt ataaaaatat ttttgatgat tattttacta aagctgagga
    35161 aggtttcaaa ggcacagcta tggaaaataa tgactcgttt actaaactaa aagagtcaac
    35221 tcaaaaatta ttcgatgcgc agaaaaaaag gttaaataat gaagatagaa tagaaacaac
    35281 taaaaacaat gtgattgcca aacattgtca aacagtcctt tcctttttgg ttttgactag
    35341 cttttttgtg aaaaattgtg taaaatagaa tagataaacg aggggaaacc tcggaaaatt
    35401 taaaggagaa tccatctaat ggtaaaattg gtttttgctc gccacggtga gtctgaatgg
    35461 aacaaagcta accttttcac tggttgggct gatgttgatt tgtctgaaaa aggtacacaa
    35521 caagcgattg acgctggtaa attgatcaaa gaagctggta tcaaatttga ccaagcttac
    35581 acttcagtat tgaaacgtgc tatcaaaaca actaacttgg ctcttgaagc ttctgaccaa
    35641 ttgtgggttc cagttgaaaa atcatggcgc ttgaacgaac gtcactacgg tggtttgact
    35701 ggtaaaaata aagctgaagc tgctgaacaa tttggtgatg agcaagttca catctggcgt
    35761 cgttcatacg atgtattgcc tccaaatatg gaccgtgatg atgagcactc agctcacaca
    35821 gaccgtcgtt atgcttcact tgacgactca gtaatcccag atgctgaaaa cttgaaagtg
    35881 actttggaac gtgctcttcc attctgggaa gataaaatcg ctccagctct taaagatggt
    35941 aaaaacgtat tcgtaggagc tcacggtaac tcaatccgtg cccttgtaaa acacatcaaa
    36001 ggtttgtcag atgacgagat catggacgtg gaaatcccta acttcccacc attggtattc
    36061 gaattcgacg aaaaattgaa cgtcgtttct gaatactacc ttggaaaata aaaaattgta
    36121 agtctagaat tgatttctag gctttttatg ttagtatgga agtatgataa ggaataaaaa
    36181 acaagattat gtactggcct acaagcaacc agtttcaacc acttacatgg gttgggaaga
    36241 agaagcttta ccgataggca atggttcttt aggagcaaaa gtatttggcc ttataggggc
    36301 tgaacggatt caatttaatg aaaaaagtct ctggtctgga ggtccacttc ctgatagttc
    36361 agattatcag ggtggaaatc ttcaggatca gtatgttttt ttagctgaga ttcggcaggc
    36421 tttggagaag agagattaca atctggctaa ggaactggct gagcagcacc taattgggcc
    36481 aaaaacgagt caatatggga cctatctgtc ttttggggat attcacattg agttcagcca
    36541 gcaaggtacg actttgtctc aggtgacgga ctatcagaga cagctgaata ttagtaaggc
    36601 acttgtgacg acttcttatg tctataaggg aacgcgattt gaacgtgaag cttttgcgag
    36661 ttttccagat gatctcttgg ttcagcgttt tactaaggaa ggggcggaaa ctctagattt
    36721 tactatagaa ctatccttga cctgtgattt ggcttctgat ggaaagtatg agcaggaaaa
    36781 atctgattac aaggagtgta agttggatat tactgattct catatcttga tgaagggaag
    36841 agttaaggat aatgatctgc ggtttgctag ttatctagct tgggaaacgg atggagatat
    36901 tagagtttgg tcagataggg ttcagatatc aggagccagt tatgccaatc tcttcttggc
    36961 cgctaagacg gattttgccc aaaatcctgc tagcaattat cgcaagaaac tagatttaga
    37021 gcaacaggtg atagacttgg tggacacagc taaagaaaag ggctataccc aattgaaatc
    37081 aaggcatatc gaggactacc aagccttatt ccagcgtgtt caattggatt tggaagctaa
    37141 tgttgacgca ttcactacag atgatttgtt aaaaaattat aagccacaag aagggcaggc
    37201 tttggaggag ctgttcttcc agtatggacg gtatttattg attagttcgt ccagagactg
    37261 cccagatgct ctaccagcta acctacaggg agtctggaat gcggtcgaca atcctccttg
    37321 gaattcggac tatcacttaa atgtcaatct gcagatgaat tattggccag cctatgttac
    37381 caatctccta gaggcggtct ttccggtcat caactatgta gatgatttgc gtgtctatgg
    37441 tcgtctagcg gctgtaaagt atgcaggaat cgtctctcaa aaaggtgagg aaaatggttg
    37501 gttggttcat actcaagcga ctccctttgg ttggacggca cctggttggg attactattg
    37561 gggttggtca ccagctgcca atgcgtggat gatgcaaact gtttatgaag cctattcatt
    37621 ttatagggac caagactatc tcagggagaa aatttatccc atgttgaggg aaacggttcg
    37681 tttttggaat gcctttttac ataaggatca gcaggcgcag cgttgggtgt cttctccgtc
    37741 ttattcccca gaacatgggc cgatttcgat tggcaatact tatgaccaat ctctgatttg
    37801 gcagttattt catgatttta ttcaggctgc tcaggaattg ggactggatg aggacttgtt
    37861 gactgaggtt aaggagaagt ctgatttact aaatcctttg caaatcactc aatctggtcg
    37921 aatcagggag tggtatgagg aggaagagca gtattttcaa aatgagaaag tggaggccca
    37981 gcatcggcac gcttcccatc tagtgggact ctatcctggc aatctcttta gctacaaggg
    38041 acaagagtat attgaagcgg cacgtgctag cctcaatgat cgtggagatg gcggcacagg
    38101 ctggtccaag gctaataaga tcaatctctg ggcgcgtttg ggagatggca atcgagccca
    38161 taaattattg gcagagcagt taaaaacatc caccttgcca aatctttggt gtagccatcc
    38221 tccttttcag atagatggta attttggtgc tactagtggc atggcagaaa tgttactcca
    38281 gtctcatgca gcttatctgg tacctctagc tgccctacct gatgcttggt caacaggttc
    38341 tgtttcaggc ttaatggcac gtggacattt tgaagtgagc atgagctggg aagataaaaa
    38401 actcttacag ttgaccattt tatcaaggag tggaggagat ttgcgagttt cttatccaga
    38461 tattgagaag agtgtgatta aaatgaatca agaaaaaata aaagcgaaat gcatggggaa
    38521 agattgtatt tcggtggcaa cagcagaagg tgatcttgtt caattttatt tttaagaaga
    38581 tgttataagg cagtaatttg aaacttcctt ttaataagga tttaagaata taggcagttt
    38641 ccaactagtt gaaaaagcgt tataatgata ataggaagta atactcaatg aaaatcaaag
    38701 agcacaaact aggaagctag ccgcaggttg ctcaaaacag tgttttgagg ttgtagatgg
    38761 aagctgacgt ggtttgaaga gagattttcg aggagtataa tttgtttgat agagggtggg
    38821 tctgatggct tatattgaga tgaaacactg ttacaagcgt tatcaggttg gggacacgga
    38881 gattgtggcc aatcgtgatg tgaattttga gattgaaaag ggggagctgg ttattatcct
    38941 tggtgcttca ggtgcaggca agtcaacagt tcttaacctt cttgggggaa tggataccaa
    39001 tgatgaaggg gaaatctgga ttgatggtgt taatattgcg gattatagtt cccaccagcg
    39061 caccaattac cgtagaaatg atgtggggtt tgtttttcag ttttataatc tagtttctaa
    39121 tctgacagct aaggaaaatg tggaactggc ttctgaaatt gtgacagatg ccttgaatcc
    39181 tgatcaggtc ttgacagatg taggtctggc tcatcgtctc aataactttc cagcccagct
    39241 ttctggaggg gagcaacagc gagtctccat tgcacgcgcg gtagccaaaa atcctaaaat
    39301 tctcctttgt gatgaaccga ctggagcctt ggattatcag acgggcaagc aggttttgaa
    39361 aattctccaa gacatgtctc gtcaaaaggg agcgacggtg atcatcgtga ctcataatgg
    39421 agctttggcg cccattgctg atcgcgtgat tcatatgcac gatgccagtg tcaaggatgt
    39481 ggtgctcaac cagcatcctc aggatattga cagtttggag tactagcatg atcaagcgaa
    39541 aaacttattg gaaggactta attcagtcct tcacagactc caaggggcgt tttttatcca
    39601 tcttgatcct gatgatgttg ggatctctag ccttagtagg cctcaaagta accagtccca
    39661 acatggaggc gacagctaat gcttatttaa caactgctca aaccttggat ttggcagtca
    39721 tgtctaacta tggcttggat caagcagacc aagaagaact aaaacagacg gagggcgcag
    39781 aggtcgagtt tggctatttg acagatgtga ctatggataa tgggcaggat gccattcgac
    39841 tgtactccaa accagagcga atttcaacct ttcagctaag aaagggacga cttcctcagt
    39901 cagacaggga aatcgctttg gccactcatt tgcaaggcca atacagcgtg ggacaggaga
    39961 ttagttttaa agaaaaagaa gagggtcatt cctctttaaa agaccatact tataccatta
    40021 ctggttttgt ggattcggct gaaatcctct cccagcgaga tatgggctac gcaggaagtg
    40081 gaagtgggac tctgacagcc tatggggtga ttttacctag tcaatttgat cagaaagtct
    40141 acaatatagc tcgtttgaaa tatcaagatt tagcaggttt aaatgccttt tcatcagctt
    40201 atgaagaaaa atccaagcaa catcaggaag accttgaaca aactttatca gataatggca
    40261 aggtacgtct gcaacttttg aaaaaagaag gacaagagtc tctagacaag gggcaagaga
    40321 ctcttgacaa ggctcagact aatttgcagg aaggcaagcg tcgtttagca gctgctcaag
    40381 ctcgtataca ggctcaagaa agtcaactag ccttgtttcc tcaagctcag agagagcagg
    40441 ctagtgctca acttacccaa gccaagcagg aactgggcaa ggaagaggac aaactaaagc
    40501 aagctgaaca aaatctagcc caagaaaagg aaaaattaga aaaacatcag caagtcttgg
    40561 atgatttggt ggagccaagg tatcaggttt ataatcgtca gaccatgcca ggtggtcagg
    40621 gctatcttat gtatagcaat gcttcatcca gtattcgagc agtgggcaat atctttcctg
    40681 tggtacttta tgccgtagca gccatggtga cctttacgac catgactcgc tttgtagacg
    40741 aagagcgaac tcatgcaggg atttttaagg ccttgggtta tcgtagtaag gatattatcg
    40801 ccaagtttct cctttatgga ctagtagctg ggactgtcgg aacggctcta ggtagtatac
    40861 ttggtcatta tttgctagcc agtgtaattt caagtgtcat tacaaaaggc atggtggtgg
    40921 gagaaaccca gattcagttc tattggacct atagcttact agctcttgtc ttgagctggt
    40981 tggcgagtgt gttaccagcc tatctggtgg cttggaggga acttcatgac gaagcagccc
    41041 agcttctact tcctaaacct cctgtcaaag gagctaaaat cttattggag cgtatcggtt
    41101 ttatctggcg tcgtctcagt tttactcata aggtaacagc ccgcaacatc tttcgttata
    41161 agcagagaat gttgatgaca atctttggtg tggcaggttc tgtagctctg ctctttgcag
    41221 gtttgggaat ccaatcttct gtagcaggag ttccgtctaa acagtttcaa caaatccaac
    41281 agtatcagat gcttgtctct gaaaatccta gtgcgaccaa tcaggacaag gtagagctag
    41341 cagaagtgtt gaaagggcag gagatactag cctaccagaa aatctattct aaaacgctag
    41401 acaaggattt caagggcagg gctggtcttc aaaacattac tcttatgatg atagagaagg
    41461 aagatttgac tccctttatc catcttcaac atcatcagca ggagctgaca ttaaaagatg
    41521 gcatcgttat tacagctaaa ctcgcccagc tggcaggtgt caaggttggg cagactttag
    41581 aaattgaagg taaggaacta aaggtcgctg ctattactga gaactacgtt ggtcacttta
    41641 tttatatgag tcaggctagc tatgagcaac tttacggaca gctaccccaa gccaacactt
    41701 atctggtctc attaagggat accagtgcaa ctagtatcga aagtcaggcg ggcttgctta
    41761 tgaatcaatc tgcggtgtcc agtgttgtcc aaaatgcttc agccattcga ctcttcgact
    41821 ctatcgctag ctcactcaat cagaccatga ccatcttggt catcgtatcg gttctattag
    41881 ctattgtcat cctttacaat ctgaccaata tcaacgtagc tgagagaatc cgtgaactct
    41941 ccactatcaa ggttctcggt tttcataata atgaagtcac cctctacatt taccgtgaga
    42001 cgattgtgct gtcccttgtg ggaatcgtac ttggtctggt agctggtttc tatttacacc
    42061 aatttttgat tcaaatgatt tcgcctgcga ctattctctt ttatccgcag gtaggctggg
    42121 aagtctatgt aatcccagtg gcagcagtaa gcatcatttt gaccttgctt ggtttcttcg
    42181 tcaattatta tctgagaaag gttgacatgt tagaagccct gaaatctgta gagtaaggta
    42241 gttattttta gctgattgaa cttctattta ctaatattca aaaatcctcc gtttcaaaga
    42301 gcagggaact ctttgtgaca gaggattttt tctatagggc tttagcagct gcaattgcgg
    42361 cttcgaagtt tggctcagaa ttgatattat ccacgtattc aacgtagcga atcgtattgt
    42421 cagtatcgag gacaaagact gcgcgtgcta ataggtgcca ttcgttgatc aagagggcat
    42481 aatcgcgtcc gaaagaatgg tcaaagtagt ctgaaagcat aatggcattg tcaaggcctt
    42541 cagcaccgca ccaacgtttt tgagcaaaag gtaggtccat tgaaacagtc aatacgaccg
    42601 tgttgtccag tccagccaat tcttcattaa aacgacgtgt ttgagttgag cagatgcctg
    42661 tatcgataga aggaacgaca ctcaagactt ttttcttgcc atcaaaatca gccagagatt
    42721 ttttagaaag atctgttgta gtaagagaaa aatcaagcgc cttgtcgccg acttgtagtt
    42781 gtttacctgt aaagctcaca ggatttccga gaaaagttac cataggatac tccaatcttt
    42841 tttcttccat tgtatctgaa acagtcagaa ttttccaatg atttgaccgg aaatgtgtgc
    42901 atagaaaaaa cgccagctca catgagaatg acgtttttca gaggcttatt ttgccaatcc
    42961 ttcagcaatc ttgtcaaggt tgtatttcat catgctgtag tagctgtcgc cttctttacc
    43021 ttgttctgcg atagagtcag taaagatttg tgcgtagatt gggatgtttg tgtcttgaga
    43081 aacagttttc attggacggt catccacact tgattctaca aagagtgatg gaacttttgt
    43141 ttggcgaagt ttttcaacca aggtcttgat ttgttcagga gttccttctt cttcagtatt
    43201 gatttcccag atgtaggcac ttgggacacc ataggcttta gagaagtatt tgaatgctcc
    43261 ttcgctggtt acaatgagtt tcttttcagc agggatctta ttaaatttat ccttactttc
    43321 tttatcaagt ttgtctaact tatcagtata ttctttgaga tttttttcat agaattcttt
    43381 attgttaggg tctttggcgc tcaattgttt ggcgatattt ttagcaaaaa taataccgtt
    43441 ttcaaggtta agccaagcgt gtgggtcttc ttttcctttt tcattttgac cttcaaggta
    43501 gataacatca acgccgtcgc tgactgcgaa gtagtctttg ttttcagttt tcttggcatt
    43561 ttctaccaat tttgtaaacc aagcattgcc acctgtttca aggttgatac cgttatagaa
    43621 aatcaaatca gcctcagaag ttttcttaac gtcttcagga agtggttcgt attcgtgtgg
    43681 gtcttgccca atcggaacga tactatgaag gtcaattttg tcaccagcaa tatttttagt
    43741 aatatcagcg atgattgagt ttgtagcaac aacttttagt ttttgaccag aagttgtatc
    43801 tttttttccg ctagcacatg ctacaagaat gattgcagaa agaaagagaa cgagtaatgt
    43861 acctaatttt ttcattagat cctccaattt attagggctt tgccccttat tttaacaaat
    43921 gtttattttt cagtttcaaa tatcgttgtt tgggagcgat aaagaagcta atgagaaaga
    43981 aactagcagc tgtaagcacg atactagaac ctgccgcaac attaaaacta tagccaataa
    44041 agagtcccaa aactgaagca gtagctccga aggttgagga aaggaaaatc atgcttttca
    44101 gactattagc atacagataa gcagttgcag ctggggtaat cagcatggct acaatcagga
    44161 tagttccgac actttgcatg gctgtcacag acacgagagt caggagtacc atgagaaggt
    44221 agtgatagaa attgacaggc attcccatgg ctttagccaa gagttcatca aaggaagtta
    44281 tcaagagttg cttgaagaaa atccagatta acaagaggat ggctgccccc acacccatag
    44341 taataaacat atccgtatct tggacggcca gaatattacc aaaaaggata tggaaaaggt
    44401 cagttgaact tttagcgaca ccaatcaaga tgataccgag ggctaagaaa gaagaaaagg
    44461 taatgccgat ggcggtatcg cttttgataa tcgagtttcc tttgatgtag gtaatgatga
    44521 tggcagctag caatccaaag acaatggctc cgataaagaa gtcaaggccc aagatgaagg
    44581 agagggctac acctggtaag acagcatgtg aaatggcatc tcccatgagt gacatcccgc
    44641 gtagaataat gaaacatccc acggctccag ctacaatccc gacgacaata gctgttatca
    44701 aggcattttg taggaaatgg aatttttgca atccatcgat aaattctgca atcataggtc
    44761 acctccattg aaaaagagtt gattaccgta agcttctttt agattggttt cggtaaaagt
    44821 ttcttttgtt ggaccaaagg caatcacttc tcgattgaca agtaagactt gatcgaagta
    44881 gtggggaatc ttgctgaggt cgtggtgaac gatgagaacc gtcttcccag cttttttcaa
    44941 atctctcagc gtattcatga tgatttcctc actgacagag tcaatcccag caaagggttc
    45001 atccaagagg atatagtcgg cttcctgcac caaacatctg gcaatcaaga cccgctggaa
    45061 ttgacctcca gacagttgac taatttgacg ttcagcgtag tcagctaggc cgacgatttc
    45121 aagggcctct tgcactttct tccaatgttt agcctttaaa cttcgaaaga gaggaataga
    45181 gggaaatagt cctaacgaga cgcattcctt gaccttgatg ggaaagttgt agtcgatatt
    45241 gattttttgt tcgacatagg caattcggtg taaggatttt ttaacttcct tgtcatcgag
    45301 aaatgcctga ccttgatgtg ggataattcc cagcatacct tttaatagtg ttgatttccc
    45361 agcgccgttt ggaccaatga tgccggtaat tgttggtcca tggagcacta gtgaaatatc
    45421 cttaagtgcc aacgtttctt tgtaggagac actgaggttt tcgatacgta tcataaactt
    45481 gtattcctcc tgtctcttaa tatacattaa aaaaaaaatt aagtcaagtt aatttttgaa
    45541 aaaattaaaa taataactga aaaatagatt ctaaagataa ctttcaggat aaatttctaa
    45601 attataaaac gcatagtatc aagtgtaaaa aacttggaat tatgcgtttt atcatggaaa
    45661 gattttttat aatagctaaa aaataatagt taaatggtta ttaattgcat tccctagtga
    45721 tttttgttaa gataaatgca aatacaaatg aaagcgagaa caagatgaca cgttatcaag
    45781 atgattttta tgatgctatc aatggagaat ggcaacagac agctgaaatc ccagcagata
    45841 agtctcaaac aggaggtttt gttgatttag accaggaaat tgaagacctg atgctggcga
    45901 caacagacaa gtggttagca ggtgaagaag tgcctgagga tgctatcttg gaaaactttg
    45961 tcaaatacca ccgcctagtt cgtgattttg acaagagaga agctgacggt atcacacctg
    46021 tcttaccact ccttaaagaa ttccaagaat tggaaacttt tgcggatttt acagctaaac
    46081 tagcagagtt tgagcttgca ggaaaaccaa acttccttcc ttttggtgta tcgccagact
    46141 ttatggatgc tagaatcaat gttctatggg ctagcgctcc aagcacaatc ttgccagata
    46201 cgacctacta tgcagaagaa catcctcagc gcgaagagct cttgactctt tggaaagaaa
    46261 gcagcgcaaa tctcctcaag gcttatgatt tctctgatga agaaattgaa gacttgctag
    46321 aaaaaagact tgaattggac cgccgagttg cggcagtggt gctctctaat gaagaaagtt
    46381 cagaatatgc taaactctat catccatatt cttacgaaga tttcaagaaa ttcgcgcctg
    46441 ccctaccttt ggatgacttc ttcaaagcag ttattgggca attaccagac aaggttattg
    46501 tagacgagga acgtttctgg caagcagcag agcaatttta cagtgaggaa gcctggtctc
    46561 tccttaaagc aaccttgatt ttgagtgttg tcaatctttc aaccagctat ttaacagagg
    46621 atatccgtgt tttgtctggt gcctacagcc gtgccctttc tggagttcca gaggcaaaag
    46681 ataaggtcaa agcagcttat catctagcac aggaaccttt caagcaagcc ctggggcttt
    46741 ggtacgcccg tgagaagttc tctccagaag ccaaggcgga tgtggagaaa aaagtggcaa
    46801 ccatgattga tgtctataag gagcgtctgc ttaagaatga ctggctcact ccagaaacct
    46861 gtaaacaggc tatcgtgaag ctcaatgtga tcaaacctta tattggctat ccagaagaat
    46921 tgcctgcacg ttacaaggat aaggtagtga atgaaactgc cagtcttttt gagaatgctc
    46981 tagcctttgc gcgtgtggaa atcaagcaca gttggagtaa gtggaaccag cctgtagact
    47041 ataaggaatg gggcatgcct gctcatatgg tcaatgccta ctacaatcct cagaagaacc
    47101 tgattgtctt tccagcggcc attttacagg cgcctttcta tgacttgcat cagtcatctt
    47161 ctgctaacta cggtggtatt ggggcagtga ttgcccatga aatttcccac gcctttgata
    47221 ctaacggggc ttcctttgac gaaaatggta gcctcaagga ttggtggaca gagagcgact
    47281 atgctgcctt caaggagaaa acacaaaaag tcattgacca atttgatgga caggattctt
    47341 atggagcaac cattaacggt aaattgactg tatcagaaaa cgtggctgac ttgggaggaa
    47401 tcgcagcagc gcttgaagca gctaagagag aagcagactt ctcagcagaa gagttcttct
    47461 acaacttcgg tcgcatctgg cgcatgaaag gtcgaccaga atttatgaaa cttttggcta
    47521 gcgtcgatgt gcacgcacca gccaaactcc gtgtcaatgt gcaagtacca aacttcgacg
    47581 atttctttac aacctatgat gtcaaagaag gagacggaat gtggcgttca ccagaggagc
    47641 gcgtgattat ttggtaatac aaaaaatcta gtcatcagaa aaaaggcatc caatcacgtg
    47701 tgaaaacctt gataggatgc cttttgtaat agaaagattt gctggatagt ttacttaaat
    47761 ttcgattgtc atcatcttgc tagaaaaagg gattgaaggc cttttcgtga gcgatagtag
    47821 tagctggacc atgtcctgga tagacatcgt agtttggtag ggtgaagagt tgggtctgga
    47881 tactatgaag gagttgctcc atgctaccag tcggaaggtc ggtccgtccg atagtttcgc
    47941 ggaatagagc atctcccgtc aagactaggt gagcatcagg aaagactagg gaaacaccac
    48001 cgatagagtg ccctggggtc ggtagaacct taaaacgaaa ttcctctagt tggtattctt
    48061 cgtgaaagac aaaggtgtgt tctgcaggtt ttgtgaccac atctgccata tcatcgtggc
    48121 gagggagacc ggagagatta tcgacaggag tgtagagcca gctggcttcg ctctctgcga
    48181 tatagacagg aggattgcca aacgtctcgc gaaccaagtc cagactcatg atatggtcat
    48241 aatgggcgtg ggtcaagaga atagcacaga tcggtttgtt gatcttctcg attgtctgac
    48301 gaatggcttc ccaatgacta ccaggatcga cgacgatgag gtgcttttcg ccttctagat
    48361 aataggtatt ttcataggca acaggattca cggttttatg gattttcata ctagctccaa
    48421 tctcaaagaa tgtactaata ctcttcgaaa atctcttcaa actgcgtcaa ctttatctgc
    48481 aacctcaaag cagtgctttg aacagcctgc ggctagcttt ctagtttgct ctttgatttt
    48541 cattgagtat aaattaagta tagcacagtt agggagaata ggtaaggatt taaaatgaac
    48601 ttaaaaacca gcatgactag atgaagacag gctggttatc aatttatcaa tattggaaag
    48661 gtgtcaattg cccttcatag gttgcataaa ctccgtcatt agcttgtttg atagacgtga
    48721 tgtttagagt gctaccgtag ttggcttctc gtttgtcgct atattcacta taagttatcc
    48781 tactgggcag gttctggtcg ttagcatagt attgaacgac tgttttttat agctttgctg
    48841 gctgaatagg aacaggcagc aaactcctaa cattaggaga gcaaagatag aaatagcagt
    48901 ttttttcata ggtattctcc ttataaacta aaggatagaa gaaagtatct tgaggatttt
    48961 tatactcttc gaaaatctct tcaaaccgcg tcaacgtcgc cttgccgtat atatgtgact
    49021 gactttgtca gtcttatcta caacctcaaa gcagtgcttt gagcaacctg cggctagttt
    49081 cctagtttgc tctttgattt tcattgagta ttaattccaa aatccagtca aggtaccagt
    49141 gtatgtgata cgagttccac cgtttatctt tcgtatcttc aatggaattg gggaaatcag
    49201 aaagtctttg ggttacaata tggtttccgt tcttctatct ctccttctat cacctaagtt
    49261 taaaatctaa cttcgtagta tattatgggc cgataattca gaattatcaa gcaattttga
    49321 attatttttt tcttattctg ttccaatcta gttttcatat tcttaaaaaa gtgataaaat
    49381 ggtaggaaga attggagagt agagatgccg aaagaagtga atttaacagg cgaagaagtt
    49441 gtcgctttaa ccaaagaata tttaacggaa gaggatgttc attttgtcca taaggccttg
    49501 gtctatgctg ttgaatgcca cagtggtcaa tatcgcaaat caggcgagcc ttatatcatt
    49561 caccctatcc aagtggcagg tattttagct aagctaaagc tggatgctgt aacagtagct
    49621 tgtggattct tgcatgatgt ggtggaagat acagatgcga ccttggacga tttggaaaga
    49681 gagtttggtc ctgatgtgcg ggtgattgtt gacggagtta ccaagcttgg caaggtcgag
    49741 tacaaatcaa tcgaggagca attagcggaa aatcatcgca agatgctcat ggccatgtct
    49801 gaggacatcc gcgttatttt ggtcaaactg tctgaccgct tgcacaatat gcggaccctg
    49861 aaacatcttc gaaaagacaa gcaggagcgt atttccaaag aaaccatgga aatctatgcc
    49921 ccacttgccc atcgtttggg gatttccagt gtcaaatggg aattagaaga cttgtctttc
    49981 cgttatctca atccaacgga gttttacaag attacccata tgatgaagga aaagcgcagg
    50041 gagcgtgagg ccttggtgga tgaggtagtc acaaaattag aggagtatac gacagaacgt
    50101 cacttgaaag ggaagattta tggtcgtccc aagcatattt actcaatttt ccgcaaaatg
    50161 caggacaaga gaaaacggtt tgaggaaatc tatgatctga ttgctattcg ttgtatttta
    50221 gatacccaaa gtgatgttta tgccatgctt ggttacgtgc atgaattttg gaaaccgatg
    50281 ccaggtcgct tcaaagacta tattgccaac cgcaaggcca atggttatca gtctatccat
    50341 acgactgttt atgggccaaa agggccgatt gaattccaga ttcgaaccaa ggaaatgcac
    50401 gaggtggctg agtacggggt tgcggctcac tgggcttata agaaaggtat aaaggggcaa
    50461 gttaacagca aggaatcagc tattggaatg aactggatca aggagatgat ggagctccaa
    50521 gaccaggctg atgatgctaa ggaatttgtg gactctgtta aggaaaacta tctggctgag
    50581 gagatttacg tttttacccc agatggagct gtccgttccc ttcccaaaga ttcaggaccg
    50641 attgattttg cctacgaaat ccataccaag gtcggtgaaa aagcaactgg tgccaaggtc
    50701 aatggccgca tggttccact gacaaccaag ttaaagacag gggatcaggt tgaaattatc
    50761 gccaacccga actcctttgg acctagccgt gactggctca atatggtcaa gactagcaag
    50821 gcgcgcaata agattcgcca gttctttaaa aaccaagata aggaattgtc tgtcaacaag
    50881 ggtcgtgaga tgctgatggc tcagttccaa gaaaatggct atgtggcaaa taaatttatg
    50941 gacaagcgcc acatggatca agttctgcaa aagaccagtt acaagacaga agactccctc
    51001 tttgcggcca ttggttttgg ggaaatcggt gcgattaccg tctttaaccg tctgactgaa
    51061 aaggaacgcc gtgaggaaga gcgtgccaag gccaaggctg aggcagagga gcttgtcaaa
    51121 ggtggcgagg tcaaggttga aaataaagaa actctcaagg tcaagcatga ggggggagtg
    51181 gttattgaag gtgcttctgg tctcctagtg cggattgcta agtgttgtaa ccccgtgcct
    51241 ggtgacgata ttgttggcta cattaccaag ggtcgtggtg tggctattca ccgtgtggac
    51301 tgtatgaacc tgcgtgccca agaaaactac gagcaacgtc tccttgatgt ggaatgggaa
    51361 gaccagtact ctagctcaaa taaggagtat atggcccata tcgatatcta cggtctcaac
    51421 cgtacaggac tgttgaacga tgtactgcaa gttctttcaa atacaaccaa gaatatttca
    51481 acggtcaatg cccaaccaac caaggatatg aagtttgcta atatccatgt gtccttcggt
    51541 attgccaacc tctctacact gaccacggtt gtcgataaaa ttaagagtgt gccagaagtt
    51601 tactctgtca aacggaccaa cggctagttg tcctagctct tactagaaag gctattatga
    51661 aaatcattat ccaacgggtt aaaaaagccc aagtgagtat agaaggccag attcagggaa
    51721 aaatcaatca gggactttta ttgctagttg gtgttggacc agaggaccaa gaggaagatt
    51781 tggactatgc tgtgagaaaa ctggtcaata tgcggatttt ttcagacgca gaaggcaaga
    51841 tgaacctgtc tgtcaaagat attgaaggag aaatcctctc tatttctcag tttaccctct
    51901 ttgcggatac taagagaggc aatcgtccag cctttacagg ggcagctaaa cctgatatgg
    51961 catcagactt ctatgatgct ttcaatcaaa aattagcgca agaagtgccc gttcagacag
    52021 gtatctttgg agcagatatg caggttgagc tggttaataa cggacctgtt accattatcc
    52081 tagatactaa aaagagataa gaaagaccaa gcccagtcgg cttggtcttt ctcatctatc
    52141 ataaaatact ccaaaaagaa atcggttctt gatatgcttg ggggaagtct cttttcaggc
    52201 tttggcagat gcgataggaa gggatgagat gtcctaggat gaggagagtt ccctgaagga
    52261 aaagtggaat atcacttaaa gacaccaagg agagaatcat caggctatcc cataggagaa
    52321 tttgtaaagc aaaacgccag aatctcggtc taatctggga atagagttga ctaaagtggt
    52381 cacaaagttg gtttgaaaga taggtcaata gcacaggatg aaagaaaatg agccaaccgc
    52441 tataaatcaa aatccagtcc caagtaagcc ccccttttaa atgtcaaaaa tgccagcatg
    52501 attccatcaa tgacaaggag ttgaatggtt ttgatgaaga tgattttttt catgataaaa
    52561 cctccttttc cttagagaca ctcccataaa gagatgtgtt tgtcgtaaaa gtctggatag
    52621 ttttctctta ggtagtcagc tgtcatataa taaaaagtag aatggcaagc agtgataatt
    52681 gacataagag atgaaaaacg ctgagaacta atgaaggcta agagaacaaa aaaatagaaa
    52741 atcaatggtg agaaccccta aatagtagaa gcgaatcttt ttattgattt gaggataaat
    52801 ctcagcgaat tgatgtttga gtcggacgat caagagaaat agcaggagtc cttgagcaag
    52861 gaagaaaatt aaaccagaga gcaagagcca ctcaaaagat gtctcgagtc taatgataaa
    52921 aaatgcaaat agtagcaaat caataactgc aattgctata aaatggattc tatagagttt
    52981 tttcatgaca agacctccct cttttatcta acttcattct actctaaaag aatgggagtt
    53041 acaactaaaa tgataaaaat agcagagggg agattctctt aagttgacta gtattcttta
    53101 tttgagtttc cttctattat ctaacttctt catcattcca gacaaataaa gctccgattg
    53161 cattgaggat ataaaagatg tatttaccga tattggcgaa gtttccttga ataccagctt
    53221 ttgtcagctg aacgaaattg taaatcaacc aaaagcccca ctgtccctca ttgccaatga
    53281 attcaaagca ttggcaatga gggacagtgc aaaggcaata gttgttacgt aggcaaggag
    53341 attcatcttg cccccatatc cgatatagtt ggtcacaaag gcaaagagga aggcgatgat
    53401 ggaaatgatg atggccgcca attttacctg tttttggctc atttggttgg gtctgccttc
    53461 ttgcgaagct ttccatttct ttatagcaaa ggtataaatg aggaaggtga cgggataggt
    53521 aatgatggcc gccttatttc caaggatata atcaatagca ccggacaaaa tggtattaac
    53581 aataccaaag taatttcccc atttgcttaa tttccccgtg aaacgagtgg acaacatgga
    53641 aatcccaacg ttggttacgg aaatcaatcc aaagggtaca agagctgtcc atagtcccca
    53701 gtctacaaat ttatcgaggc gtgagttgag ataaccagat gcaatcgcaa tcccaacgac
    53761 caaagcaacc ccgaagaggt caaatcattt agatgtagca aaaattttta gtgatttttt
    53821 cataggttaa actacctttc tttttttcaa atactctacc accaaatgaa agtaaaatca
    53881 aatgatagaa ataaaaccct gaaaataaaa ctttcagggt tggtagggga cttgagaaat
    53941 tagttgattt tctcgacata gagttgtttt gcaatgtcca tattcacttg taaatcctcg
    54001 tcgttactga ggatagtgaa ggtattgctg aagccatcaa actgcttgac ttggagctgg
    54061 tcaccgatgt gaagtgagtg cttgtccaga taatggagaa tgtcaaaact atcgtgcacc
    54121 cgagtcaggc ggtaggcgcc agcttccttg atatcagcta gtgggaggtt attgatttca
    54181 acgaggagtt ctcccttggc aggaatagtt cctccgtggg ggcaggtttt agggaaacct
    54241 agcagtttat ctagtctttc cacgaacagg tcagagacag tgtgttccaa gacctcagct
    54301 tcctcgtgaa tctggtcact tgtatagtct aaatgatgaa ctagaaaaac ttcaatcaag
    54361 cggtgcttac gatagagctc agagaccagt ttgagaccga ggtcagtcag tagatagcca
    54421 cattccttgt cctttaggat gagattttca cttttcattc gtttgatcat ttcagttacg
    54481 gcagggggag agacttgcat gcgagccgca atttccttgt tggtaatctt atgcaggtct
    54541 atgccaattt cataaataca ttttagatag tcttctttgt ttggggtcat tcgtttcctc
    54601 ttgtctaata tctttatcta gtatatcaaa aaaagctaga tttctctagc tgtgactttt
    54661 tatgttatac ttattgcaag agaaaaaacg aggagatgga tatgacgaaa atagctcttc
    54721 tttcagatat tcatggaaat accaccgcct tggaggctgt tttggcagat gctcagcaga
    54781 taggagtgga tgaatactgg cttttgggag atattctcat gccagggaca ggacgtagaa
    54841 ggattttgga cttgttggat caactaccga ttacggctag agttttggga aactgggaag
    54901 acagtctttg gcatggtgtc cgtaaggaat tggacagtac tcgccccagt caacgctatc
    54961 tcttgcgcca gtgccagtat gttttagagg aaatttccct agaagaaatt gaagtgctcc
    55021 acaatcaacc tcttcaaatt catcgtcagt ttggggattt gacggtggga attagccatc
    55081 atctgcctga taagaactgg gggcgagagt tgattcatac tggcaaacaa gaggagtttg
    55141 accgcttggt gactcatcct ccctgtgata ttgctgttta tggacatatt caccagcagt
    55201 tgcttcgtta cgggactggt gggcaattga ttgtcaatcc gggttcgatt ggccaacctt
    55261 tctttttgga cgctcagcta cggaaggact tgcgggccca gtatatgatt ttggagtttg
    55321 atgacaaagg cctggtagat atggacttcc gacgggtaga ctacgatgtg gcagcggaat
    55381 tgcagctggc taaagacctg agacttccct attttgaggt ttactatgaa agtctggtca
    55441 atgggatcca ccatactcat catcaggaat ttttgagaga attggctcag aaagagggct
    55501 gcgatcggga gttagatgac tggttgaaaa gtggtaacga ttgacattac aactaaaaag
    55561 ggtataataa tagaaaaaga agagtagagg cagggtagcc tcgtaaaaag gagaagagga
    55621 tgcaaattcc aagtagattt accattgcga ctcatatgct gataatcatt gccctcgagg
    55681 ggaaggaaag caaggtgacc agtgattttc tggctgctag tgtcggggtc aatcctgtca
    55741 ttatcagaaa gatcttgtcc cagttgaaga aggcagagct gatttcagta gcgcgtggaa
    55801 cgggcggaac agagattgtc aaggacctta aggatattag tcttttagat gtttatcagg
    55861 cggtcgaatg tcttggtaag acaggtcaac tcttcagttt ccatgacaat ccgaatccaa
    55921 attgccctgt aggagctcat attcatgatg ttttggatca aaaattggag agaattcagt
    55981 tgactatgga ggcagaactt ggtcaaacca gtctagaaaa agtcgtggcc gatgcagaga
    56041 gtcagatgaa ggattaagag ggataaatgc cctctttttt ctttggataa ttatgataaa
    56101 atgtagctat taaaggagta agaaatgtat ctcgttatag gaattgtatt agcctttata
    56161 gtgtcatttt ggaaggataa tagaagtttg tggaatccag tattattttt attatccctc
    56221 atttcaagtt atttttatct atcctacctt ttttataaaa atggatacga gaatgttcag
    56281 ttagcttttt atgtatttgc ctttgtctta cttccttttt tgctttttct aagtggcatc
    56341 tttttaatct ataatggggt cattttgttg aagcgagagg gacgttccaa gccccattat
    56401 ctctcaatgc tctttgattt ttattgacta ttagattcta tttaaaaaga cttagaatgc
    56461 acatgaaagt atgtattcta ggtcttttgt tttgtataca tttaattttc aagagtatta
    56521 tctatttttc catgcctggt aacgagtatc aatcaataac tgggtaaggc gacccaaggt
    56581 ttctctttct tctggagtga gggattgagc ttggacaaag agatgatgaa tgtattcaag
    56641 cgcctttaag gaagccaagt cattgataga gctaatacca gcctcaagaa tagtgccaaa
    56701 gaagaggtcg aagtagagct gaagttcttc gtcagggact gtggccaccc attctttaaa
    56761 ggttgtgtct acttgctggc tatcactgtt ggtcttatcc agttggacga agtgcttgtc
    56821 ctcaatctgc caactaaagg tatcgtgctg ggcgatgcca cccagggcag tactctgaac
    56881 gatgatttgg tgagcaggaa tttccagcat cataccgata atggaacctt gtggaatgaa
    56941 tatcttgctt ctatccatta tcctttgata acccgcagtc tgtgtcaatt cttgatggag
    57001 accaggtgca tcaaatgtat aaactgctgt gatctgattt tgcaaacttt gctcaatttg
    57061 gctagcagca tagatagcga gatttcctcc cttggaatgc ccagctagaa taaccttttg
    57121 cttaggatga tgggcaaaaa agttctttaa atagcgaagg gcgtgctttt gagcaggaat
    57181 ttccttcata taggtcaggt ggaaaacttc cttccagcca atgatactgt catctgtccc
    57241 acgaaagaca atcagatagg tatcgaggct gacacgataa gtcatagccg caaattgctt
    57301 ttgcagttca gggtcgatgt cgttgataaa atgggagagt ttgcaatttt tgaagcgctt
    57361 gtgttgagcc aattcatcta ataattgaag gcgatttttg ctagtaagca tggtgggatc
    57421 tcttggaacc tgaggtgcta gatctaaaag acgttgagga agtgtggaga ccagattatc
    57481 aaaggagagg taggtgattt ctattaaggt tagaatgtct aactcattca agggaaggtc
    57541 gtaataagaa tcatatgcga catctttcag atagtcaaaa atattggcca taagagctcc
    57601 tttcttttta tttatcttag caaatttccc tcaaattagc tagtagcatt gcctgtttgt
    57661 actggctaaa aacaggctat ttcaaattca gtttcagacc atctggcatg gaaaaatctg
    57721 ttataataat agaaaaggag aagcgcatgc acaagatttt attaatagaa gatgatcagg
    57781 tcattcgtca acaggtcggg aaaatgctct ctgaatgggg atttgaagtg gtcctggtag
    57841 aagactttat ggaagttttg agtctatttg ttcagtcgga acctcatctg gtcctcatgg
    57901 atattggttt gcccttgttt aatggttatc actggtgtca ggaaatccgc aagatttcca
    57961 aggtacctat catgtttctt tcttcgagag accaggctat ggatattgtc atggcaatca
    58021 atatgggggc ggatgacttt gtgaccaagc cttttgacca gcaggttctt ttagctaagg
    58081 ttcagggctt gttgcgtcgt tcctatgagt ttgggcgtga tgagagtttg ctggaatatg
    58141 ctggtgttat cctcaatacc aaatccatgg atttacatta tcaagggcaa gtcttgaatt
    58201 tgaccaagaa tgaattccag attttacgcg tgttatttga gcatgcaggc aacatcgtag
    58261 cacgtgacga cctgatgcgg gaactttgga acagtgactt tttcattgat gataataccc
    58321 tctctgtcaa tgtggctcgt ttgcgtaaaa agttggagga gcagggattg gtaggattta
    58381 tcgagaccaa gaaaggaata gggtacggat tgaagcatgc ttgattggaa acaatttttt
    58441 ctagcctatc tgcgctcccg tagtcgtctt tttatctatc tgctttcttt ggcatttctt
    58501 gtcttactct ttcagttttt atttgccagt ctaggaattt acttcctcta ctttttcttc
    58561 ttgtgttgct ttgtaaccat cttatttttc acttgggaca tattggtgga aacgcaggtc
    58621 tatcgccagg aacttctcta tggagagagg gaagccaagt ctcctttgga aatagcttta
    58681 gcagaaaaat tagaagcgcg tgagatggaa ctctatcagc agaggtcaaa agcagaaaga
    58741 aaactgacgg atttgctgga ttactatacc ttgtgggtcc atcagataaa gacccccatt
    58801 gcagccagtc aactcttagt tgcagaagtg gtcgaccgcc aactgaagca gcagctagaa
    58861 caggaaattt tcaaaatcga ctcctatacc aacctagttt tacagtacct gcgtttagaa
    58921 agtttccatg atgatttggt cttaaagcag gttcaaattg aggacttggt caaggaaata
    58981 attcgtaaat atgctctttt ctttattcaa aaaggcttaa atgtcaatct acatgacctt
    59041 gataaagaaa tcgtgacgga taaaaagtgg ctgctagtgg ttattgagca aatcatctca
    59101 aacagtctca agtacaccaa ggaaggtggt ctggagattt atatggatga ccaagagctt
    59161 tgtatcaaag atacgggaat cgggataaaa aacagtgatg tcctccgagt atttgaacgt
    59221 ggcttttcag gatacaatgg ccgtttgacc cagcagtcct ctggacttgg cctttatcta
    59281 tctaagaaaa tttctgaaga actggggcac cagattcgta tcgagtctga ggtcggaaaa
    59341 ggaacgacag tgcggattca gtttgctcaa gtgaacttag tccttgagta aaaatagatg
    59401 agaaaaagcc tccagattgg aggcttttat gctagactct tatttctcaa cgcgtgattt
    59461 gttggcgata tcagctagga tagcttgaac aaaattatca actgagacag tttgtgtttc
    59521 tttttggccg tagcgacgaa cgttgactgt ttcgtcttcc atttctttgt ctccaacaat
    59581 taattggtaa ggaatcttgc tggtttgtga agcacggatc ttgaactgca ttttttcatt
    59641 gcgctcatct acgtctgcac ggacaccgcg gtcacggagt ttcttggcta cttcccaagc
    59701 gtagtccacg tgtttttcgt tagatactgg gataagggtt acttggtgtg gtgccagcca
    59761 tgttgggaag gcacccttgt agttctcaat caagatagct gtgaagcgtt ccatagttga
    59821 gataacccca cggtggatca tgactggacg gtgatcttcg ccatcagctc cgatgtattt
    59881 gaggtcgaag cgttctggca acaagaaatc aagttggata gtagaaaggg tttcttcttt
    59941 tccaagggca gttttaatct ggatatccaa ttttggtccg tagaaggccg cttcaccttc
    60001 ggcttcaaag tagtccacgc ccatttcatc aagagctgca cgaagcatgg tttgggcatt
    60061 ttcccacatc tcatcgttat caaagtactt atgagtatct tgagggtcac gaagagagag
    60121 gcggaagcgg tagtcagtca agttgaagtc ttcataaaca tcgataatca actgaagggc
    60181 acgttggaat tcttcttgga tttgttctgg agtaacgaat aggtgaccgt cgttgagtga
    60241 catttcacgt acacgttgaa ggccagtgag ggcaccagat ttttcgtaac ggtgcatcat
    60301 accgatttca gcgatacgga ttggcaattc acggtaagag tgaacatggt gtttgaaaac
    60361 ttggatgtgg tgcggacagt tcattggacg aaggacaaat tcttccccgt cacccatgtc
    60421 catggttggg aacatgtctt cttggtaatg atcccagtgg ccagaagtct tgtaaagctc
    60481 aacagaagca agtggtggag tgtagacgtg ttggtagcca gaagccaact ctttgtttac
    60541 gatgtagcgt tccaattcac gacggatagt cgcaccattt ggcaaccaga atggcaaacc
    60601 ttgtcccact tcttgtgaaa tcataaagag gtcaagctct ttaccaagtt tacggtggtc
    60661 acgttcctta gcttcttcac gcatttgaag gtagtttttc aagtctttct tttcaaacca
    60721 agctgtaccg tagatacgtt gcatcatagc gttgtcgctg tttccacgcc agtacgcacc
    60781 agctacatgg agaaggtgga agatttggat acgacctgtt gatggaacgt gaggtccacg
    60841 gcagaggtct acatattcac cctgacgata gatagtcaaa ccgccttcgt cttctgagtg
    60901 ttcttcaatc aattccaact tgtaagggtc atttttgaag atttcacgtg cctcgtcttt
    60961 agtcacttct tcacgaatag atgggaagtt ttctttgacg attttttgca tttcttcttc
    61021 gatacgagga aggtcttcgt tagagatttg accagctgtg ttgtcagtat cgtagtagaa
    61081 accatcttcg atggctggac caactcccaa gtgaatgtct gggaaaagac gacgagctgc
    61141 ttgggcgaac aagtgagctg ctgagtggcg caagattgga agggcatctt cgtgatcagg
    61201 tgtcacaatt tcgatgcttc catcttcagt gatagcgcga gtagtgtcga tgagtttgcc
    61261 gttgaattta ccagccaagg cttttttagc tagggaattg ctgatagatt gggcaatttc
    61321 aaaagttgtt acgccagatt cgaattcacg aacagcgcca tctgggaaag taatgttaat
    61381 catgatgttc tcctttttta ttatttcata gtttctaagc attgattttt tatcatcaga
    61441 ctacttccaa gtcctaacgt tcaattgctt ttctttatca gagaggaagt tttccatttc
    61501 cgtcagaatg tctatatcca aacgttgaga aagttctaat agccaccaga tattttctga
    61561 aagtttttgt tccagtgtgt agggtgtttc atcatagtag cgtccttgct ttgtcatcac
    61621 cagtcgttgg aaatttccaa tatcattaga taaagccaag gggtcttctt ctaccgtcca
    61681 cttggaatca tgatgcttaa cttccagttc gtgataagct tgtcggattg cccaactgcg
    61741 ctccactaat tcttgcaact ccataattag tatcctaata aaaaaatgcg acatcctcga
    61801 aaggacgtcg caacgtggtt ccaccttcat ttatgtacct caaaagagag ggacacctct
    61861 gattggctct aacgtggcca ccgttttatg ttttcataaa aaactcaaga gtagtatcag
    61921 tttagacttc ctatgcgttt ccagcaacca cgcactctct agtagaaagg gactaagtga
    61981 cttgtctcta tggattatta tagcatgatt gtgagatttt tcaaggattt tgtgaaagtt
    62041 ttttgttttt cattttttgt agaatatgct tgatgctaat accagaatcc atgcccacca
    62101 gagcaactgt ttcatagatt agcaagtaaa ttagtataaa ctcaccaaag gttatgatag
    62161 taaagtaaaa gagcagtccg ttaccaacta accatcaaag tgagaaacgg aaacggtagc
    62221 tatagagtaa cgatacaatc aagattacca gaggtgtaaa gaagagaaga ttgtttatat
    62281 agagttcctt gagtgtaagg gggtcagaaa caactagtaa gaacaactca taaagtggcc
    62341 aataaaagaa taatatgacc agatagtagg ggagatggga atagaatcta cgcatgataa
    62401 tcacctcgtt ttaaaaaaac agacaactta gatctcttgc tatgattatt atagcatgtt
    62461 taaaacaaga aagtaaattt gttggcaaag aagatttttt ttcactagaa tcatggttag
    62521 ttttcttggt agaaatattt tgataataat taagcaaaac tattgacatt gattattaag
    62581 agtgtcacaa ttgttgtaac taaaataatt acaataagag aggtataaaa aatgaaacta
    62641 gcagttattg cagcaaatgg acaagcgggg aaagcaattg ttgaagaagt agtcaaacga
    62701 ggacatgaag taacggctat tgttcgttct gaaaacaaaa gtcaatctga gtctattatt
    62761 aaaaaagatt tatttgagtt gacaaaagat gatcttactg gatttgatgc tgttatttca
    62821 gcgtttggtg cttatacacc agatacgcta ccgctccaca gcaaatcaat cgaactattt
    62881 aatcagcttc ttgctggaac acagacacgt tttctagttg tagggggagc aggaagtctt
    62941 tatatagatg aaacaaaaac gacacgactt ttagatacgt ctgattttcc tgaagaattt
    63001 aagtcactag caaaagctca agcggatgaa ttggatcttc ttcgtacaaa aaataatctc
    63061 aactggactt ttgtcagtcc tgctgtagat tttattcccg atggtgaaaa aacaggaaac
    63121 tacattctag caggagaaat ttttactact aatgaaaaag gaataagcca gattagttat
    63181 gcagattatg ctattggatt ggtagatgaa cttgaaaaag gtcatcatat aaaagaacgt
    63241 atctctttac ttgaaaaata ataactatga gagtattaat gtttgacaga aaatttaaat
    63301 cttggtaaaa tagggattgt cgtaaagaca aataacttct tcttggttac aggcatgcca
    63361 acctgtcact cggatgaagc caaataaaaa ggagaaacat catggcaatc tcaaaagaga
    63421 aaaaaaatga aatcattgca caatatgcac gtcacgaagg tgatacaggt tcagtagagg
    63481 ttcaagttgc tgtccttact tgggaaatca accaccttaa cgaacacatc aaacaacaca
    63541 aaaaagacca cgctacttac cgtggattga tgaaaaaaat cggtcgccgt cgtaacttgc
    63601 ttgcatactt gcgtaaaaac gacgttaacc gttaccgtga gttgatcaac tctctaggac
    63661 ttcgtcgcta attcaagata caaaggccgt caaaaacaca aagcaaaaat aggaaaattg
    63721 acgaagaaac ttcagtttct aggagatttt atcttttttg ccaagtgctt aggccgtgtt
    63781 caattgagca tatcttgata ataaagctac tctaaattgg gtagctttgt tgcgttgtca
    63841 ccttacctcg ctatactcaa gtataatctt cggttacggt tcctagcact gtaaggtaaa
    63901 ataaactagc ttttctccct tcggggagat ttttttgttt cactgaaagt ttcgtacgat
    63961 cttcacctcg tcccctagtc tataaacgat ttatctagca agaatcatga tgctaagggc
    64021 gtcaaaaatc cgtatgaaaa tagggaaatg acacagtgtt cgatgagcac aaggagtttc
    64081 atctttttca ctaggatttt agcccgggct aaaatcagct ctctgacttc agagggcttt
    64141 tttattgagg ttttatcggt aacaattttg gagactacaa aaacctcaaa tggtatcagc
    64201 taattacacc ataaaggtgc gcagttactc ggcttttcaa gccgagtagc tgtatgcaag
    64261 ccccctagaa gagcccactc tttacaaagt aaagtatagt atgttatact ttacatggaa
    64321 gtagtcactg aattccagtt agaaattact ttgtaactac gttttgagga ggagtaaaat
    64381 gctttcctac gttcgacatt acccactagc gatagctaaa ttaatgtgtc tgtgctctcc
    64441 taaaatctgc tgatttatta ctgactaata caggaggttt tttttatggg acagacaatc
    64501 atatctgcta ttggtgttta tatttccacc agtatcgatt atttaattat tttaattatt
    64561 ttatttgcac agctatcaca gaataaacag aaatggcata tttatgcggg gcaatatcta
    64621 ggcacaggct tacttgtagg ggcgagttta gttgctgctt atgtcgttaa tttcgtgcct
    64681 gaagaatgga tggttggatt gcttggttta atccctatct atttagggat tcgctttgca
    64741 attgttggag aagatgcgga agaagaagag gaagaaatta ttgaaagatt agaacaaagc
    64801 aaggcaaatc aactgttttg gacagttaca ttgctgacaa ttgcgtctgg cggagataat
    64861 ttaggtatct atatacctta ttttgcttcg ttagattggt cacagaccct cgtggccttg
    64921 cttgtgtttg taatcggcat aattatcttt tgcgagatta gtcgggtgtt atcctctatt
    64981 ccgttaatat tcgagacaat tgaaaaatac gagcgaatca ttgtgccctt agtattcatt
    65041 ctacttggac tatacatcat gtatgaaaat ggcacgatag agacttttct gatcgtgtag
    65101 atttttttgt ttcactagga ttttagcccg agctcaaatc agctctctga ttttcagggg
    65161 gctttttcat tgagtataaa tggacaatct taaagttact ctattgtaga gtggcttttg
    65221 atttgattag gagattctta taaatatagt aaaatgaaat aagaatagga caaatcgatc
    65281 aggacagtca aatcgatttc taaaaatgtt ttagaagtag aggtgtacta ttctagttcc
    65341 aatctactat ataaatgaaa accttagctg tttggccaag gttcatttct tctatgcaag
    65401 ttcttctctt ttcttatctg ggttccagat gaagcttgcg ataaagctaa agatgatggt
    65461 taggatagcg aggataatag caaggatgag ggcagggatg cggataaacc accagagtgg
    65521 atttggtttt ttatcattgt gccattgttt cgtttcttcg tccagacgtt ggaattctgt
    65581 ttgaatacga ttggcgactg tttcaatgcc ttcatcattc attttcttga tatctgagat
    65641 atcgattgga tttccaaagt tcatatcgac acgttcacgg ctaatcaagc ccttcaaagt
    65701 catgggaccg gtgtaggtaa ccggcatgat acggaccttg gccattttgg caatcagtgc
    65761 tgcgcccccc ttgacatcgt ttgagtggcg gctaccactt ggaaacatga tgagagagca
    65821 gtcacttttt ttgagaacgt tgataggata tttgatggct gaggcgctgg gattttcacg
    65881 gtcgatggga aaggcgccac acatacgaat ccaccaacca aagatacggt tggtaaagag
    65941 ttcttttttt gccataaaga tgaactgttt tggcttggtc gcaaaggcca tataaacagg
    66001 atcccaccag gtacggtgag gcgcaactaa aatataattt tcatcttgat taggaatttt
    66061 atcagtatta tgatagtgag cattgccatt gatggaccat aagagcaata caactaatcc
    66121 acgcaaataa gtataaaaca tgcgatctcc ttcaattgtt ttcttgttat tattatacct
    66181 tatcaaagga gggctggcaa acttttccct tgactagatg catatttggg atgaaattag
    66241 aattctgtta aaaaaaatga tataatagaa tttatggata aaaataagat tatgggatta
    66301 acccaaagag aagtcaagga aagacaggct gagggtttgg tcaatgactt taccgcatca
    66361 gccagtacca gcacttggca aatcgttaaa cgaaatgtct ttaccctttt taacgctttg
    66421 aactttgcca ttgctttggc ccttgccttt gtgcaggctt ggagcaatct ggtcttcttt
    66481 gctgttatct gctttaacgc tttttctggg attgtgaccg agctacgagc caaacacatg
    66541 gtggacaagc tcaatctcat gaccaaggaa aaggtcaaaa ccatccgtga tggtcaggaa
    66601 gttgctctta atcctgaaga attagtgcta ggagatgtca ttcgtttgtc tgcaggagag
    66661 cagattccta gtgatgcctt ggttttggaa ggctttgcgg aagtcaatga agccatgtta
    66721 acgggagaaa gtgatttggt gcaaaaggaa gttgacggct tacttttgtc aggaagtttc
    66781 ctagccagtg ggtcagtttt atctcaagtt caccatgtcg gtgcagacaa ctatgctgcc
    66841 aaactcatgc ttgaggctaa gaccgttaaa ctcatcaact cccgtatcat gaaatcgctg
    66901 gacaagttgg ctggttttac tgggaagatt atcattccct ttggtctggc tctcttgctg
    66961 gaagccttgc ttttaaaagg cctgcctctc aagtcatctg ttgtaaactc gtcgacagct
    67021 cttttgggaa tgttgcctaa gggaattgcc cttttgacca ttacttcgct cttgactgca
    67081 gtgattaagc taggtttgaa aaaggtcttg gtgcaggaga tgtactctgt tgagaccttg
    67141 gcgcgcgtgg atatgctctg tctggacaag acgggtacca tcacccaagg aaagatgcag
    67201 gtggaggctg ttcttccact gacggaaact tatggtgaag aggctgttgc cagcatcctg
    67261 accagctata tggcccatag tgaggataaa aatccaacag ctcaagccat tcgccagcgt
    67321 tttgtgggag atgttgctta tcctatgatt tccaatcttc ccttctcgag cgaccgcaag
    67381 tggggggcta tggagttaga aggtttggga atagttttct taggggcacc tgagatgttg
    67441 ctggattctg aagtcccaga agccagggag gccttggaga gaggatcacg tgtcttggtc
    67501 ttagctctca gtcaggagaa attagaccat cacaaaccac agaaaccatc tgatattcag
    67561 gctctagcct tgctggaaat cttggacccc attcgagagg gagcagcaga gacgctggac
    67621 tatctccgtt ctcaggaggt gggactcaag attatctctg gtgacaatcc agttacggtg
    67681 tccagcattg cccagaaggc tggttttgcg gactatcaca actatgtaga ttgctcaaaa
    67741 atcaccgatg aggaattgat ggccatggcg gaggagacag cgattttcgg acgtgtttcc
    67801 cctcatcaaa agaaactcat catccaaacg ttgaaaaaag cgggtcatac aacggctatg
    67861 acaggggacg gggttaatga tatcttggcc cttcgtgagg cggattgttc tatcgtgatg
    67921 gcggaggggg atccagcaac ccgtcagatt gccaatctgg ttctcttaaa ctcagacttt
    67981 aatgatgttc ctgagattct cttcgagggt cgtcgcgtgg tcaataacat tgcccacatc
    68041 gccccgattt tcttgataaa gaccatctat tccttcctgt tagcagtcat ctgtattgcc
    68101 agtgctttac taggtcggtc agagtggatt ttgattttcc ccttcattcc gatccagatt
    68161 accatgattg accagtttgt ggaaggtttc ccaccattcg ttttgacttt tgagcgaaat
    68221 atcaaacctg tcgagccaaa cttcctcaga agatccatgc ttcgtgccct accaagtgcc
    68281 ctcatggtcg tgtttagcgt tctttttgtg aaaatctttg gaacgagtca aggttggtct
    68341 gagttagaaa tctcaactct cctctattat ctcttggggt caattggttt cttatccgta
    68401 tttagagcct gcatgccatt cactctatgg cgagtcctct tgattgtctg gtcagtagga
    68461 ggcttcctag ccacagctct cttcccaaga atccaaaaac tgcttgaaat ttcaaccttg
    68521 acagaacaaa cgttgcctgt ttatggtgtc atgatgttgg tctttacagt gattttcatc
    68581 ctgactagtc gctatcaagc tagaaaataa agaaagactg caatctgtgg attgcagttt
    68641 ttttaggtac aagattgcca gccgaaatgt ggtataataa gaggtaatag agttttggaa
    68701 agtgagagaa gatgatttca aagagattag aattggtagc ttcctttgtg tcacaggggg
    68761 ctattttact agatgtggga agtgaccatg cttatctgcc tatcgagttg gttgagagag
    68821 gccaaatcaa aagcgctatt gcaggtgagg tggtggaagg tccctatcag tctgcggtta
    68881 aaaatgttga ggctcacggc ctaaaggaga aaatccaagt ccgtttagcc aatggcttgg
    68941 cagcttttga agagactgac caagtgtctg tcattaccat tgctggcatg ggtggtcgtt
    69001 tgattgctag gattttagaa gaaggtttgg ggaagttagc taatgtagaa cgtttgatcc
    69061 tccagcccaa taatcgtgaa gacgacttgc gtatctggct acaggatcat ggattccaga
    69121 ttgtagcaga aagcatctta gaagaagctg gaaagtttta tgagattttg gtggtggaag
    69181 caggacaaat gaagctatca gccagtgatg ttcgctttgg tcccttcttg tccaaagaag
    69241 tcagtccagt atttgtccaa aaatggcaaa aagaagctga gaagctagag ttcgccctcg
    69301 gacaaatccc agaaaaaaat ctggaagaac gtcaagttct agtagataag attcaagcta
    69361 tcaaggaggt gctccatgtt agcaagtgaa gtgatccaag cttatgaagc cttttgccct
    69421 caggaatttt ctatggaggg agacagctgt ggtctgcaaa ttggcacttt agacaagggt
    69481 atccaaaggg tcatggtggc tctcgatatt cgtgaagaga cggtggctga agccattgaa
    69541 aagggtgtag acttgattat cgtcaagcac gcgcctatct ttcgtcctat caaggacttg
    69601 cttgccagcc gtccgcaaaa tcagatttac atcgacctga ttaagcatga catcgcagtt
    69661 tatgtcagcc ataccaatat tgatatcgtt gaaaatgggc tcaatgactg gttttgtcag
    69721 atgctaggaa tcgaggagac gacttatctg caggaaacag gtccagaacg tggaattgga
    69781 cgtattggga atattcagcc tcagacattt tgggaattgg cccaacaggt caagcaagtc
    69841 tttgacctag atagccttcg aatggtgcat tatcaagagg atgatttgca gaagcctatt
    69901 tcaagagtag caatttgtgg tggaagcggg cagtctttct ataaggatgc tttggcaaag
    69961 ggggcagatg tctatatcac tggtgatatc tactaccata ctgctcagga tatgctgtct
    70021 gatggcttgt tagcattgga tccaggtcac tatatcgaag tgctttttgt ggaaaaaatc
    70081 gcaacactcc ttactcaatg gaaagagaaa aaaggctggg aactagagat tttacctagt
    70141 caagcatcga ccaatccttt ccgtcatatc tagttagaaa gtgaagacaa tgaaaaaagt
    70201 tgccattatt ggagcaggaa ttgtgggagc aacagctgcc tactacctct cgagagaaag
    70261 tgacctagag gtgaccgttt ttgaccatga gcaaggtcaa gccaccaagg ccgcagcagg
    70321 aattatcagt ccttggtttt ccaaacgccg taataaagcc tggtacaaga tggcgcgctt
    70381 gggggctgat ttttatgtgg atttattagc tgatttagag aaatcaggac aagaaatcga
    70441 cttttaccag cgttcgggag tctttctctt gaaaaaggat gaatccaatt tggaagaact
    70501 ttatcaactg gccctccagc gcagagaaga atctcccttg atagggcaat tagccattct
    70561 gaaccaagcc tcagctaatg aattattccc tggtttgcag ggatttgacc gcctgctcta
    70621 tgcttctggt ggagcgagag tagatggtca cctcttagta actcgtttgc tggaagccag
    70681 tcaggtcaag ttggtcaaag aaaaagtgac tctgacactc ttatcatcag gctaccagat
    70741 tggcgaagag gtgtttgatc aggttatttt ggcaacggga gcttggttgg gggacatgtt
    70801 agagccttta ggttatgaag tggatgtccg tcctcaaaaa ggacaactac gagattatca
    70861 gcttgcccaa gacatggaag attaccctgt tgtcatgcca gaaggggagt gggatttgat
    70921 tccctttgca ggtgggaaat tatccttggg cgctacccat gaaaatgaca tgggatttga
    70981 tttgacggta gatgaaccct tgctccaaca aatggaggag gcggccttgc ctcattaccc
    71041 agttttagct agagtgactt caagggctga gcgtgtggga atccgtgcct ataccagtga
    71101 tttctctccc ttctttgggc aggtgccaga attggcaggt gtctatgcag ccagtggact
    71161 aggttcatca ggcctcacaa ctggtcctat cattggttac catctagccc aactgatcca
    71221 agacaaggag ttgaccttgg accctgaaaa ttacccaatt gaaaactatg tcaaacgagt
    71281 aaaaagcgaa taatactcaa tgaaaatcaa agaacaaact aggaaactag ccgcgggtta
    71341 ctcaaagcac tgctttgagg ttgtggatag aactgacgaa gtcagctcaa aacactgttt
    71401 tgaggttgtg gatagaactg acgaagtcag taaccatacc catggcaagg cgacgttgac
    71461 gtggtttgaa ttggattttc gaagagtata agcattttac tgaaatttta tcaggtagtt
    71521 taggatggca aatgacattc cctgtcaaaa atggtaaaat aagaaaaaat gatctgagaa
    71581 tcgaggaaaa aagatgcaag aaaagatttt ggtaactggt ggtgccggtt ttattggaac
    71641 ccacactgtt attgaattga tccaagcagg ccatcaagtt gttgtggtgg ataatcttgt
    71701 caatagcaat cgtaagagtt tagaagttgt tgaaagaatc acaggagttg agattccttt
    71761 ctatgaggca gatattcgtg acacagatac cctcagagat attttcaagc aggaagaacc
    71821 gactggtgtc attcactttg ctggtttgaa ggctgttggc gaatcaacac gtatccctct
    71881 tgcctactat gacaacaata tcgctggaac tgtcagcctt ttgaaagcca tggaagaaaa
    71941 caactgtaaa aacatcatct tcagttcttc tgcgacagtt tacggagatc cgcacacagt
    72001 gcccatcttg gaagatttcc cactttcagt gacaaaccca tacggtcgta ccaagctcat
    72061 gctagaggaa attttgaccg atatttacaa agcagactca gaatggaatg ttgtcttgct
    72121 tcgttacttt aacccaatcg gagcccatga gagtggtgat ttgggagaaa atccaaacgg
    72181 tattccaaac aatctcttgc catatgtgac tcaagtagcc gttggaaaat tagagcaagt
    72241 gcaagtgttt ggagacgatt acgatacgga agatggaaca ggtgttcgtg actatatcca
    72301 cgttgtcgat ttggctaagg gtcacgttgc agctttgaaa aaaatccaaa aaggttcagg
    72361 actaaacgtt tataaccttg gaactggtaa aggttactca gttcttgaaa ttatccaaaa
    72421 catggaaaaa gcggtgggac gtcctattcc ttaccgcatc gtagaacgtc gcccaggtga
    72481 tatcgctgcc tgctactcag acccagcaaa agctaaagca gaactcggtt gggaagcaga
    72541 actcgacatc acccaaatgt gtgaagacgc atggcgttgg caaagcaagc atccaaatgg
    72601 atttgaagac taagatgatg atttcaatca tcgtcccttg tttaaacgaa gaggaagtac
    72661 ttcctctttt ttatcaggct ctggaagctt tacttccaga tttggaaaca gaaatcgagt
    72721 atgtctttgt cgatgatgga tcaagtgatg ggaccttgga actcttaaag gcctatcggg
    72781 agcaaaatcc ggcagtccat tatatttctt tctctcgaaa ttttggcaaa gaagcagccc
    72841 tttatgcagg cttgcaatat gcgacaggag atttggtggt ggtgatggat gcagacctcc
    72901 aagatcctcc tagtatgttg tttgagatga aaaatgtact agacaaaaat gtagacttgg
    72961 actgcgttgg gacacggaga actagtcggg agggagaacc cttctttcgc agtttctgtg
    73021 ctgttctctt ttatcgcctc atgcaaaaaa tcagcccagt agctctgccg tcgggtgtcc
    73081 gtgattttcg tatgatgaga aggtctgtag tcgatgccat tttaagcttg accgagtcca
    73141 atcgtttttc aaaggggctc ttcgcctggg tgggtttcaa aacctactat ttggactatc
    73201 caaatgtcga aaggcaggct ggcaagacaa gttggagttt taggcaactc tttttctact
    73261 ccattgaagg gattattaat ttttcagatt ttcccttgat tatagccttt gtagctggtc
    73321 tcctatcttg ttttctttct ctgctgatga ccttttttgt tgtggttcgg accctcattt
    73381 tgggcaatcc gacatctggt tggacctctc tgatggctgt tattctcttt cttggaggca
    73441 ttcaactctt gaccattggg attctcggca agtatatcag taagatttat ttagagacta
    73501 aaaaaagacc actttatctt atcaaagaaa aaagtgacct tcctgatttt acagaaaaaa
    73561 ataaagtgaa aagactataa ttttacatgg aaatgtgcta aactagaggg agtggattat
    73621 cgcccttgat ttaggcttcc tggtttccaa tcagggcgcg agttgggcaa tttttaacag
    73681 cctctaagac atcctgacta ggagaaattt ctttttccag ttggtcaggg tcatcgtaaa
    73741 aacgcacgat tccattatcg tggtaatcaa ataaatcaga ataagtttgg caaagcccac
    73801 aggcgataca tcgttcaggt ataagtgtga ttttcatgtt catatttata ttgtaataag
    73861 aaaagtaaaa aaaaacaagg agtaaggtat ggcaaaagaa ccgtggcaag aagatatcta
    73921 tgatcaagaa gaatcaagag cagagcgtcg gcatcgaaac cacggagggg ctgataggat
    73981 ggctaatcgt attttgacga tcctagctag tattttcttt gtaattgtgg tggtgatggt
    74041 catcgttctc atctatctat catcgggggg aagtaatcgc acagcagcct taaaagactt
    74101 tcatgattct gatgcaagtg tagtacaaat ctcatcttca agcagttctc atcctgagca
    74161 gagttcagag ccagaatcta cttctagtag ttcagaagaa gctgctaatc ctgaaggaac
    74221 gattaaagtt ctcgcaggag aaggggaagc agctattgcc gctcgtgcag gaatctccat
    74281 tgctcagtta gaggccttga atcctgggca catggctaca ggatcttggt ttgctaatcc
    74341 aggtgatgtt ataaaaataa aataggagcc gatatgaaaa caattcaaat tgctattgat
    74401 ggtcctgctt ccagcggtaa gagtacggtc gcaaagatta ttgctaagga ttttggattc
    74461 acctaccttg atacaggagc tatgtatcgt gcagcgacct atatggctct taagaaccaa
    74521 ttaggagttg aagaagtcga agcccttcta gccttgttgg accagcatcc aatcagcttt
    74581 ggacgttcag aaactggaga ccagcttgtt tttgtaggag atgtggatat tacccatcct
    74641 atccgtgaaa atgaagtgac caatcatgtt tctgctattg cagcaattcc tgaagtgcgt
    74701 gagaaactgg tttctctcca acaagaaatt gcccagcaag gcgggattgt catggatggt
    74761 cgcgatattg gaactgttgt attgccacaa gcagaattga aaattttcct agtagcttct
    74821 gttgatgaga gagcagagcg tcgttacaag gaaaatattg ccaagggaat tgaaacagac
    74881 cttgaaaccc taaaaaagga aattgctgcg cgtgactaca aggatagtca tcgtgagact
    74941 tctcctctca aacaagcaga ggatgctgtc taccttgata caactggttt gaacattcaa
    75001 gaagtagttg aaaaaatcaa agcagaagct gaaaaaagaa tgtaaatgta gaaaagccga
    75061 tagattgata tcggtttttt tctaaatttg tcaaaatgct gattttaggg tataatagtt
    75121 gctgttcgag aaattttgat tttcaaagaa tagtgaatga tgataaggag aaaccatgaa
    75181 caatttacca aattgtccaa aatgtaactc agagtatgtc tacgaagacg gtgccctact
    75241 ggtttgccca gagtgtgctc atgagtggaa tcctgctgaa gttgcagaag tagaagaagg
    75301 tcttgtcgct atcgatgcca acggaaataa attgactgat ggtgatacag taactctcat
    75361 caaggacttg aaagtaaaag gtgcgccaaa agatttgaaa caagggacgc gcgtgaaaaa
    75421 tatccgcatc gtagaaggcg atcacaatat cgactgtaag attgatggtt ttggtgccat
    75481 gaaacttaaa tcagagtttg tgaggaagat ttaagcatgt caaaacacta taaacttgta
    75541 ttttatagcc gtatcttctt gtttctagcg gcttttacgg gagtttatct tgaaattact
    75601 aagcatggtg gttttgggat gcttctctat tacacggttc tgtccaacct cttggtaact
    75661 atttttaccc tttatcttct aaaggttatg agccgtgtag gtgaaaattg gcaaaggcca
    75721 agtctcttgc gcttaaaagg tggggtcacc atgagtatca tgattacctg tgtgatttac
    75781 catttcctct tggcgcccat tgcgactaat ttctataccc tagaaaattt cctttgccac
    75841 tatatcgttc ccatctggtt tttagcggat accctctttt ttgacaaaca gggtcaatac
    75901 aagatttggg atccagcagt gtggaccatt ttaccctttc tgtatatgat gtttgctctt
    75961 tttaatggct tggttctaaa actcaatatt ccaaatgcca aggataatcc tttcccttac
    76021 ttctttttga atgtgaacaa gggttggaat gttgtgttta agtggtgtct gattatcttt
    76081 gttgcctata tggtagcagg atttattttc tactttatca agcaaatcaa gagaaagtca
    76141 tcctaatact cttcgaaaat ctcttcaaac cacgttagtt tccatctgca acctcaaaac
    76201 actgttttga acaacctgcg gctagctttc tagtttgctc tttgattttc attgagtatg
    76261 agatacaagg gattcatttt cgaatttaag aaggagtcta caaaccaatg aggcttcttc
    76321 ttttcttgct tatttgataa ctatcaaaaa agtagaagat taagagaaat atagaaagag
    76381 atttcatgaa acaattttta gaacgggcca gcattttggc tctctccctc gttttgatta
    76441 cctccttttc catttcgagt gccctaccag ccatgtttga ctattatcag ggttattcta
    76501 aggaacaaat tgagctcttg gtgagcttgc cttcctttgg aatcatgatg atgttactgc
    76561 taaatggttt cttagaaaaa atatttcctg agcgcttaca gattagtttg ggcttgctga
    76621 ttttatcatt gagcggtaca gctcccttct ggtaccaagc ctatcccttt gtctttggaa
    76681 cacggcttct ctttggtttg ggtcttggga tgatcaatgc caaggccatt tctattatca
    76741 gtgaacgcta ccaaggaaaa aggcgaattc agatgttagg gctacgcgct tctgcagagg
    76801 tcgttggagc ttctctcatt accttggccg tcggtcagtt gttggccttt ggttggacag
    76861 ctatctttct agcctatagt gctggatttt tggtgatgcc cctttatctg ctctttgtcc
    76921 cttatggaaa atcaaagaaa gaagtcaaga aaagagcgaa ggaagcaagt cgtttaactc
    76981 gagaaatgaa aggcttgatt tttaccttag ctatcgaagc ggcagttgta gtttgtacca
    77041 atacagctat taccatccgt attccaagtt tgatggtgga aagaggattg ggggatgccc
    77101 agttatctag ttttgttctt agtatcatgc agttgatcgg gattgtggct ggggtgagtt
    77161 tttctttctt gatttctatc tttaaagaga aactgctcct ctggtctggt attacctttg
    77221 gcttggggca aatcgtgatt gccttgtctt catccttgtg ggtggtagta gcaggaagtg
    77281 ttctggctgg atttgcctat agtgtagtct tgacgacggt ctttcaactt gtctctgaac
    77341 gaattccagc taaactcctc aatcaagcaa cttcatttgc tgtattaggc tgtagtttcg
    77401 gagcctttac gaccccattt gttctaggtg caattggctt actaactcac aatgggatgt
    77461 tggtctttag tatcttagga ggttggttga ttgtaatctc tatctttgtc atgtacctac
    77521 ttcagaagag agcttaggat tgattcctaa gtttttcttt tgatactcaa tgaaaatcaa
    77581 agagcatagt tgattgagtt tggaatagta cgctgtagct gctaaaatat ttctagaaat
    77641 taatttgact tttctaatag agttattcat atcttatttc aatctactat agaaagctag
    77701 ccgcaggttg ctcaaaatag tgtgttgagg ttgcagatgg aaactgacgt ggtttgaaga
    77761 gattttcgaa gagtatgaga tttttatacc catacaatat ttgttttagg tccttgttta
    77821 cagactaatt tcttgataaa atagaggtta tgacgagata taaagcaact atttcctatg
    77881 atggttatgc ctttgctggc tttcagcgcc agtctcatgc gcgtagcgtt caggaagaaa
    77941 ttgaaaaaac cttgaccaga ttaaataaag ggcaaaccat tactgttcac ggtgctggta
    78001 ggacagatag tggggttcat gccctgggac aggtcattca ttttgacctg ccttatcaga
    78061 tggatgagga gaaactccgt tttgccttgg atacccagtc tcctgaagat attgatgtga
    78121 tttcgattga gcttgtggca gatgattttc attgccgtta tgccaaacat agcaagacct
    78181 atgagtttat tgtggataga ggacgtccca aaaatcctat gcgccgtcac tatgccaccc
    78241 actttcccta cccactcgat gtggaacgaa tgcagattgc aatcaaaaag ctagagggaa
    78301 cccatgattt taccggtttt acagcctctg ggactagtgt agaggataag gttcgcacca
    78361 tcacagaagc tagtttaata gtcgatgaga caggacaatt tttgaccttt accttttcag
    78421 gaaatggttt cttgtataaa cagattcgca atatggtggg gactcttctc aaaatcggta
    78481 acaaccgcat gccagtagag cagattgatc tcatcttgga gaagaaggac aggcaacttg
    78541 caggtcccac tgcagcacca aatggtttgt atttaaagga gattcgttat gaagaataat
    78601 cgtattttag cactttctgg aaatgatatt tttagtggtg gtggactgtc agctgatttg
    78661 gctacctata ccttgaacgg cttgcatggg tttgtagcag tgacttgttt gacagccttg
    78721 acagaaaaag gatttgaagt ctttccaact gatgatacca tttttcaaca tgaattagat
    78781 agcttacgtg atgtggaatt tgggggaatt aagattggtc ttctccctac tgtcagtgtg
    78841 gctgagaagg ccttggactt tatcaaacaa cgcccaggag tacctgtggt gttggatcct
    78901 gtcttggtct gcaaggaaac gcatgatgta gctgtcagtg agctctgcca agagttgatt
    78961 cgctttttcc cttatgtcag tgtgattacg cctaatctcc cagaagcaga attattatcc
    79021 ggtcaggaaa ttaaaacctt ggaagacatg aaaactgcag cgcagaaatt gcatgattta
    79081 ggagcgccag cagtcattat caagggaggc aatcgtctta gtcaggacaa ggctgtggat
    79141 gtcttttatg atggacagac ctttactatc ctagaaaatc cagttatcca aggccaaaat
    79201 gctggtgcag gttgtacctt tgcctctagc attgccagtc acttgattaa aggtgataaa
    79261 cttttgccag cagtagaaag ctctaaggct ttcgtttatc gtgctattgc acaagcagat
    79321 cagtatggag taagacaata tgaagcaaac aaaaacaact aaaatcgccc ttgtatccct
    79381 attaaccgcc ctttctgtgg ttctaggtta tttcttaaaa atcccaacac ctacaggaat
    79441 tctaactctt ttagatgctg gtgtcttctt tgcggccttt tactttggta gtcgtgaagg
    79501 agcggtagtc ggaggactag caagtttctt gattgacctc ttatcaggct accctcagtg
    79561 gatgttcttt agcttggtca accatggctt gcagggattt ttcgcaggat ttaaaggaaa
    79621 aagtcagtgg ttaggcctta ttttagcaac tattgccatg gtaggaggct acgccttggg
    79681 ttctactttg atgaatggct gggcagcagc cctcccagaa attctaccaa atttcatgca
    79741 aaatatggta gggatgattg taggatttat tcttagtcaa agtatcaaga agattaagta
    79801 atactcttcg aaaatctctt caaaccacgt cagcttccat ctgcaacctc aaaacactgt
    79861 tttgagcagc ctgaggctag ctttctagtt tgcactttga ttttcattga gtataaagag
    79921 gttgagtaaa aagtatttca aataagaaaa acgcatagta tcaggtgttg aatgaactac
    79981 ccccc
//
LOCUS       DAVMJI010000006        75141 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.006, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000006 DAVMJI010000000
VERSION     DAVMJI010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75141
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.006"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..1228
                     /locus_tag="VYR58_000435"
     CDS             <1..1228
                     /locus_tag="VYR58_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="asparagine synthase"
                     /protein_id="HEV3621654.1"
                     /translation="CSIYSTSLKKVMKLSHVPVILNNKKIQEFMRNGFILDSNTLVTE
                     INKLEYFSYISVNNTLRICGIDYNDSNNFTKEQVLKNWDSMLRESILRVYSEAGEANI
                     TLSSGFDSNYILYTLANYTNSSINAFCIGGEKGINEIPEVTKIAKFYGINLLVDTVMS
                     QDLEYFPDIVWRLEGSLFECGVILQYYLGRLLFQKGNTSIFCGESADEIMTFKYHSVN
                     YNQFCNDKQKSVYFSYSDYPFYVTNSIVLKKNNLLLHSFGIHPRYPYKMSEIVEMSKK
                     ISNLNDKKEFHKKNCELRFQDSVLDNINSVPGTTHLFSCLNIQTLVKIILYIFRYNSC
                     MKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIERILKYLYICLFNEIFIIKNKVNFF
                     DDVEFNQTLSEFLDKL"
     gene            1240..1989
                     /locus_tag="VYR58_000436"
     CDS             1240..1989
                     /locus_tag="VYR58_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV3621655.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYEYLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPCVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISLILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            2002..3174
                     /locus_tag="VYR58_000437"
                     /pseudo
     CDS             2002..3174
                     /locus_tag="VYR58_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            3569..4432
                     /locus_tag="VYR58_000438"
     CDS             3569..4432
                     /locus_tag="VYR58_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV3621656.1"
                     /translation="MIEKMELGEFYKELRLARKLKQTDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMRIGRKVVNRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKDAIHSLNKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFIQSLQVLENPQLTALFE
                     LRLQQYKKLID"
     gene            4718..4951
                     /locus_tag="VYR58_000439"
     CDS             4718..4951
                     /locus_tag="VYR58_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621657.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            4973..5650
                     /locus_tag="VYR58_000440"
     CDS             4973..5650
                     /locus_tag="VYR58_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3621658.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            5662..6327
                     /locus_tag="VYR58_000441"
     CDS             5662..6327
                     /locus_tag="VYR58_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3621659.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            6399..7625
                     /locus_tag="VYR58_000442"
     CDS             6399..7625
                     /locus_tag="VYR58_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV3621660.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(8067..8144)
                     /locus_tag="VYR58_000443"
                     /pseudo
     CDS             complement(8067..8144)
                     /locus_tag="VYR58_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8215..8871
                     /locus_tag="VYR58_000444"
     CDS             8215..8871
                     /locus_tag="VYR58_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV3621661.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            8861..9184
                     /locus_tag="VYR58_000445"
     CDS             8861..9184
                     /locus_tag="VYR58_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV3621662.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            9288..10118
                     /locus_tag="VYR58_000446"
     CDS             9288..10118
                     /locus_tag="VYR58_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV3621663.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            10272..11126
                     /locus_tag="VYR58_000447"
     CDS             10272..11126
                     /locus_tag="VYR58_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV3621664.1"
                     /translation="MKIKKWLGLVALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            11226..12599
                     /locus_tag="VYR58_000448"
     CDS             11226..12599
                     /locus_tag="VYR58_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV3621665.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            12592..13653
                     /locus_tag="VYR58_000449"
     CDS             12592..13653
                     /locus_tag="VYR58_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV3621666.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMAKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            13655..14347
                     /locus_tag="VYR58_000450"
     CDS             13655..14347
                     /locus_tag="VYR58_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3621667.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(14377..14946)
                     /locus_tag="VYR58_000451"
     CDS             complement(14377..14946)
                     /locus_tag="VYR58_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV3621668.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPTPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            15081..15695
                     /locus_tag="VYR58_000452"
     CDS             15081..15695
                     /locus_tag="VYR58_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV3621669.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            15697..17343
                     /locus_tag="VYR58_000453"
     CDS             15697..17343
                     /locus_tag="VYR58_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV3621670.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHMGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            17355..18641
                     /locus_tag="VYR58_000454"
     CDS             17355..18641
                     /locus_tag="VYR58_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3621671.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            18693..19226
                     /locus_tag="VYR58_000455"
     CDS             18693..19226
                     /locus_tag="VYR58_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3621672.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            19304..19774
                     /gene="nrdI"
                     /locus_tag="VYR58_000456"
     CDS             19304..19774
                     /gene="nrdI"
                     /locus_tag="VYR58_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV3621673.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(20067..21329)
                     /locus_tag="VYR58_000457"
     CDS             complement(20067..21329)
                     /locus_tag="VYR58_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV3621674.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(21639..22097)
                     /locus_tag="VYR58_000458"
     CDS             complement(21639..22097)
                     /locus_tag="VYR58_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV3621675.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(22094..22534)
                     /locus_tag="VYR58_000459"
     CDS             complement(22094..22534)
                     /locus_tag="VYR58_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3621676.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            22740..24689
                     /gene="mutL"
                     /locus_tag="VYR58_000460"
     CDS             22740..24689
                     /gene="mutL"
                     /locus_tag="VYR58_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV3621677.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(25014..25481)
                     /locus_tag="VYR58_000461"
     CDS             complement(25014..25481)
                     /locus_tag="VYR58_000461"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV3621678.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEISLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(25482..26687)
                     /locus_tag="VYR58_000462"
     CDS             complement(25482..26687)
                     /locus_tag="VYR58_000462"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV3621679.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(26707..27342)
                     /gene="ribE"
                     /locus_tag="VYR58_000463"
     CDS             complement(26707..27342)
                     /gene="ribE"
                     /locus_tag="VYR58_000463"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV3621680.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(27327..28427)
                     /gene="ribD"
                     /locus_tag="VYR58_000464"
     CDS             complement(27327..28427)
                     /gene="ribD"
                     /locus_tag="VYR58_000464"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV3621681.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNGAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(28562..28676)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            28833..29426
                     /gene="ruvA"
                     /locus_tag="VYR58_000465"
     CDS             28833..29426
                     /gene="ruvA"
                     /locus_tag="VYR58_000465"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV3621682.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASVENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            29436..29999
                     /locus_tag="VYR58_000466"
     CDS             29436..29999
                     /locus_tag="VYR58_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV3621683.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPVKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            29996..30673
                     /locus_tag="VYR58_000467"
                     /pseudo
     CDS             29996..30673
                     /locus_tag="VYR58_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(30814..31845)
                     /locus_tag="VYR58_000468"
     CDS             complement(30814..31845)
                     /locus_tag="VYR58_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV3621684.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEEPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDEIFHDDYKEALLDIIDNNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(32100..32783)
                     /locus_tag="VYR58_000469"
     CDS             complement(32100..32783)
                     /locus_tag="VYR58_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV3621685.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPH
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(32795..33739)
                     /locus_tag="VYR58_000470"
     CDS             complement(32795..33739)
                     /locus_tag="VYR58_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV3621686.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            33871..36702
                     /gene="uvrA"
                     /locus_tag="VYR58_000471"
     CDS             33871..36702
                     /gene="uvrA"
                     /locus_tag="VYR58_000471"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV3621687.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKNVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMTAFGVDMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVVTNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            36695..37756
                     /locus_tag="VYR58_000472"
     CDS             36695..37756
                     /locus_tag="VYR58_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV3621688.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            37888..38286
                     /gene="spx"
                     /locus_tag="VYR58_000473"
     CDS             37888..38286
                     /gene="spx"
                     /locus_tag="VYR58_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV3621689.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            38352..38921
                     /locus_tag="VYR58_000474"
     CDS             38352..38921
                     /locus_tag="VYR58_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV3621690.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            39008..39274
                     /locus_tag="VYR58_000475"
     CDS             39008..39274
                     /locus_tag="VYR58_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV3621691.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            39278..39697
                     /gene="ruvX"
                     /locus_tag="VYR58_000476"
     CDS             39278..39697
                     /gene="ruvX"
                     /locus_tag="VYR58_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV3621692.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            39713..40018
                     /locus_tag="VYR58_000477"
     CDS             39713..40018
                     /locus_tag="VYR58_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV3621693.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            40629..41879
                     /locus_tag="VYR58_000478"
     CDS             40629..41879
                     /locus_tag="VYR58_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV3621694.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISIFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            41876..42406
                     /locus_tag="VYR58_000479"
     CDS             41876..42406
                     /locus_tag="VYR58_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV3621695.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTG
                     QDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIV
                     VDDMDRDPSDQIVLTK"
     gene            42552..44084
                     /gene="cls"
                     /locus_tag="VYR58_000480"
     CDS             42552..44084
                     /gene="cls"
                     /locus_tag="VYR58_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV3621696.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            44162..44305
                     /locus_tag="VYR58_000481"
     CDS             44162..44305
                     /locus_tag="VYR58_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621697.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            44342..45880
                     /locus_tag="VYR58_000482"
     CDS             44342..45880
                     /locus_tag="VYR58_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV3621698.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHNRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSLRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            46000..48207
                     /gene="nrdD"
                     /locus_tag="VYR58_000483"
     CDS             46000..48207
                     /gene="nrdD"
                     /locus_tag="VYR58_000483"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV3621699.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            48219..48359
                     /locus_tag="VYR58_000484"
     CDS             48219..48359
                     /locus_tag="VYR58_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621700.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            48403..48909
                     /locus_tag="VYR58_000485"
     CDS             48403..48909
                     /locus_tag="VYR58_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3621701.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            48902..49492
                     /gene="nrdG"
                     /locus_tag="VYR58_000486"
     CDS             48902..49492
                     /gene="nrdG"
                     /locus_tag="VYR58_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV3621702.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            49489..50106
                     /locus_tag="VYR58_000487"
     CDS             49489..50106
                     /locus_tag="VYR58_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV3621703.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            50372..50680
                     /gene="rpsJ"
                     /locus_tag="VYR58_000488"
     CDS             50372..50680
                     /gene="rpsJ"
                     /locus_tag="VYR58_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV3621704.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            50897..51523
                     /gene="rplC"
                     /locus_tag="VYR58_000489"
     CDS             50897..51523
                     /gene="rplC"
                     /locus_tag="VYR58_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV3621705.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            51548..52171
                     /gene="rplD"
                     /locus_tag="VYR58_000490"
     CDS             51548..52171
                     /gene="rplD"
                     /locus_tag="VYR58_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV3621706.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            52171..52467
                     /locus_tag="VYR58_000491"
     CDS             52171..52467
                     /locus_tag="VYR58_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV3621707.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            52485..53318
                     /gene="rplB"
                     /locus_tag="VYR58_000492"
     CDS             52485..53318
                     /gene="rplB"
                     /locus_tag="VYR58_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV3621708.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            53422..53703
                     /gene="rpsS"
                     /locus_tag="VYR58_000493"
     CDS             53422..53703
                     /gene="rpsS"
                     /locus_tag="VYR58_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV3621709.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            53715..54059
                     /gene="rplV"
                     /locus_tag="VYR58_000494"
     CDS             53715..54059
                     /gene="rplV"
                     /locus_tag="VYR58_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV3621710.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            54072..54725
                     /gene="rpsC"
                     /locus_tag="VYR58_000495"
     CDS             54072..54725
                     /gene="rpsC"
                     /locus_tag="VYR58_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV3621711.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            54729..55142
                     /gene="rplP"
                     /locus_tag="VYR58_000496"
     CDS             54729..55142
                     /gene="rplP"
                     /locus_tag="VYR58_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV3621712.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            55152..55358
                     /locus_tag="VYR58_000497"
     CDS             55152..55358
                     /locus_tag="VYR58_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV3621713.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            55383..55643
                     /gene="rpsQ"
                     /locus_tag="VYR58_000498"
     CDS             55383..55643
                     /gene="rpsQ"
                     /locus_tag="VYR58_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV3621714.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            55669..56037
                     /gene="rplN"
                     /locus_tag="VYR58_000499"
     CDS             55669..56037
                     /gene="rplN"
                     /locus_tag="VYR58_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV3621715.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            56115..56420
                     /gene="rplX"
                     /locus_tag="VYR58_000500"
     CDS             56115..56420
                     /gene="rplX"
                     /locus_tag="VYR58_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV3621716.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            56444..56986
                     /gene="rplE"
                     /locus_tag="VYR58_000501"
     CDS             56444..56986
                     /gene="rplE"
                     /locus_tag="VYR58_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV3621717.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            57004..57273
                     /gene="rpsN"
                     /locus_tag="VYR58_000502"
     CDS             57004..57273
                     /gene="rpsN"
                     /locus_tag="VYR58_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV3621718.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            57558..57956
                     /gene="rpsH"
                     /locus_tag="VYR58_000503"
     CDS             57558..57956
                     /gene="rpsH"
                     /locus_tag="VYR58_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV3621719.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            58148..58684
                     /gene="rplF"
                     /locus_tag="VYR58_000504"
     CDS             58148..58684
                     /gene="rplF"
                     /locus_tag="VYR58_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV3621720.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            58768..59124
                     /gene="rplR"
                     /locus_tag="VYR58_000505"
     CDS             58768..59124
                     /gene="rplR"
                     /locus_tag="VYR58_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV3621721.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            59142..59636
                     /gene="rpsE"
                     /locus_tag="VYR58_000506"
     CDS             59142..59636
                     /gene="rpsE"
                     /locus_tag="VYR58_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV3621722.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            59608..59832
                     /gene="rpmD"
                     /locus_tag="VYR58_000507"
     CDS             59608..59832
                     /gene="rpmD"
                     /locus_tag="VYR58_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV3621723.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            59977..60417
                     /gene="rplO"
                     /locus_tag="VYR58_000508"
     CDS             59977..60417
                     /gene="rplO"
                     /locus_tag="VYR58_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV3621724.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            60430..61740
                     /gene="secY"
                     /locus_tag="VYR58_000509"
     CDS             60430..61740
                     /gene="secY"
                     /locus_tag="VYR58_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV3621725.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            61891..62529
                     /locus_tag="VYR58_000510"
     CDS             61891..62529
                     /locus_tag="VYR58_000510"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV3621726.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKECLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            62646..62864
                     /gene="infA"
                     /locus_tag="VYR58_000511"
     CDS             62646..62864
                     /gene="infA"
                     /locus_tag="VYR58_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV3621727.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            62889..63005
                     /gene="rpmJ"
                     /locus_tag="VYR58_000512"
     CDS             62889..63005
                     /gene="rpmJ"
                     /locus_tag="VYR58_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV3621728.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            63023..63388
                     /gene="rpsM"
                     /locus_tag="VYR58_000513"
     CDS             63023..63388
                     /gene="rpsM"
                     /locus_tag="VYR58_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV3621729.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            63406..63789
                     /gene="rpsK"
                     /locus_tag="VYR58_000514"
     CDS             63406..63789
                     /gene="rpsK"
                     /locus_tag="VYR58_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV3621730.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            63832..64767
                     /locus_tag="VYR58_000515"
     CDS             63832..64767
                     /locus_tag="VYR58_000515"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV3621731.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            64779..65165
                     /gene="rplQ"
                     /locus_tag="VYR58_000516"
     CDS             64779..65165
                     /gene="rplQ"
                     /locus_tag="VYR58_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV3621732.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            65430..65696
                     /locus_tag="VYR58_000517"
     CDS             65430..65696
                     /locus_tag="VYR58_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV3621733.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            65706..67043
                     /locus_tag="VYR58_000518"
     CDS             65706..67043
                     /locus_tag="VYR58_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV3621734.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            67287..67979
                     /locus_tag="VYR58_000519"
     CDS             67287..67979
                     /locus_tag="VYR58_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV3621735.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(68082..69717)
                     /locus_tag="VYR58_000520"
                     /pseudo
     CDS             complement(68082..69717)
                     /locus_tag="VYR58_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(69707..70798)
                     /locus_tag="VYR58_000521"
     CDS             complement(69707..70798)
                     /locus_tag="VYR58_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621736.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQTIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            complement(70811..71932)
                     /locus_tag="VYR58_000522"
                     /pseudo
     CDS             complement(70811..71932)
                     /locus_tag="VYR58_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(72149..72346)
                     /locus_tag="VYR58_000523"
     CDS             complement(72149..72346)
                     /locus_tag="VYR58_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV3621737.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSSLSDISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(72421..73197)
                     /locus_tag="VYR58_000524"
     CDS             complement(72421..73197)
                     /locus_tag="VYR58_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV3621738.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            73319..74065
                     /locus_tag="VYR58_000525"
     CDS             73319..74065
                     /locus_tag="VYR58_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV3621739.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNMATLENAGIMVKVVS"
     gene            74078..75058
                     /locus_tag="VYR58_000526"
     CDS             74078..75058
                     /locus_tag="VYR58_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV3621740.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
BASE COUNT        22779 a        13638 c        16260 g        22464 t
ORIGIN      
        1 gtgttctata tatagtacat ctttaaagaa agtgatgaag ttatctcatg ttcctgttat
       61 cttaaataac aaaaaaatac aagaatttat gagaaatgga tttattttag attcaaatac
      121 tttagtaacc gaaattaata aattagaata tttctcttac atttctgtaa ataatactct
      181 tcgtatatgt ggtattgatt ataatgattc aaacaatttt actaaagaac aagtattaaa
      241 gaattgggac tctatgctac gtgaatctat attaagagtg tatagtgaag caggagaggc
      301 taatattaca ctatcatctg gttttgattc aaattatata ttatatacat tagcgaatta
      361 tacgaattct tcaattaatg cattttgcat aggaggagaa aaaggaatta atgagattcc
      421 tgaagtaact aaaattgcaa aattttatgg tataaattta ttagttgata ctgtaatgag
      481 ccaagattta gaatattttc ccgatatagt atggagattg gaaggaagtc tctttgaatg
      541 tggtgtcata ctgcagtact atttaggcag gttgttgttc caaaaaggga acacaagtat
      601 tttttgtggc gagtcagcgg atgaaataat gacttttaag tatcattctg tgaactacaa
      661 tcaattttgt aatgataaac agaagtcagt atattttagt tattccgact atccatttta
      721 tgttacaaat tcaattgttt taaagaaaaa taacctactt ttgcatagtt ttggcattca
      781 tcctagatat ccatataaaa tgtctgagat tgttgaaatg tctaaaaaaa tatcaaatct
      841 aaacgataaa aaagaatttc acaaaaagaa ctgtgagttg aggtttcaag atagtgttct
      901 tgataacata aatagtgtcc cgggtacaac tcatttattt agttgtttaa atattcaaac
      961 attagtaaaa attattttat atatttttcg atacaacagt tgtatgaaaa tatttaattt
     1021 tagagataaa gagcttatct tttttaataa gattgtaaat gggctgatac aaaatattga
     1081 ggagaattta gaggatgata ttgaaaggat attgaaatat ttatatatat gtttatttaa
     1141 cgaaatattc attattaaga ataaggtgaa tttttttgat gatgtggaat ttaatcagac
     1201 acttagtgag tttttagata aattgtagag ggaatggtta tgagtaacaa tactaagtat
     1261 atctttttat ctccacattt agatgacgca attttttcct gtggtgatta tatttcaaaa
     1321 ttaacttcag aaggagaaat tgtacttgtt attactatat tttctggtta ccctttgagc
     1381 caacagctac agccctctgc taagcaattt cataagttgt gtaaccttgg gaaatatccg
     1441 attgaagaaa ggaagaaaga agacaggtta gcttgtgaac gtctacaatg tgattttaga
     1501 cacttatcgt actatgaata tctctatagg aaagatagaa atggcaattt tctataccgt
     1561 catatctata gtgaattaaa aaatgaggac acattaaaga atgatatcat aaaagagctg
     1621 ttaatgcatt tagacgacaa atgtgtcgta tattgtccgc tttcacttgg tgaccatgtt
     1681 gatcatgttt ttgtgaatag tattggaagg gcacttgaat ttatgcgtta taaagtaata
     1741 tattatgagg acttcccatg tgtaagtgat agtagtatgg ttagttatat gggaaaaact
     1801 aaagaattaa aaatgtatca agaggaactt gatgaaaaac attatattga tagaatatca
     1861 ttaatattgt gctataaatc tcagattttg ataatctgga aatcagttga aaaactttta
     1921 aacaatatta aagagttgta tttaaggaat ggggcagctt attctattag attttggatt
     1981 aagaaataag gaagtagttt tatgaatata gcagtaattg gtttggggca tgttgggctg
     2041 gcctacgcgt tactatttgc atctaaatat aaagttgttg catatgatat agattctgta
     2101 aaaataaata atttaaaaaa gggcattctt ccatctaaaa atgaagagct tatgaagttt
     2161 ttttgcgaga ataacttaaa tattactttt tttgatacat tttctgaaat taaaaataat
     2221 attgattatt atattattgc gcttccgaca gattatgatg agaaaattgg tagttttaat
     2281 acatatgaaa tcgaacaaac ggtatcgaag attctgaggg taaaacctaa tggaaagatt
     2341 atttgaaagt caacagttcc gatcggcttt tcaaacaaat taaaaaggct gtttgataca
     2401 aaaaatatca tttttgtccc tgaatttttg agagaaggtt gttctatata tgataattta
     2461 tatccaagtc gcatagttgt tggagatgag acagttgaag gaagaaaaat tgcagagttg
     2521 ttcctttcga ttagtactca tagtattgcc aatattaaaa atgttatgtt agtttctcct
     2581 actgaagcag aagcaattaa gcttttttct aacacattct tagctctccg tgttgctttt
     2641 tttaatgaac tagatttttt tgctgagagg agaagtttaa atgctgaagt tgtaataaaa
     2701 ggtgtttgtt tagatccaag aattggaaat ttttataata atccttcttt tggatttgga
     2761 ggatattgtc ttcccaaaga tactaaacaa ttaaaaaaag aatttataga aataaatgcc
     2821 ccagtgatag aagcgattga tatttcaaac acaaatagaa aacagttcat agttaaacaa
     2881 atattggaac gaaagccaaa gatagtagga atatataaat tggggatgaa atataattca
     2941 gataattaca aagagtcagc tattttaagt ataattaatg aactattgat tgtcggtata
     3001 aaaattttag tatatgaacc aaatttaaac gttagtatag ataacgtaat ttttgaaaag
     3061 aattttgaac tatttacaaa acaaagtgat ctaattgttg caaatagatg ggataggggc
     3121 cttgaagctt ataaagataa agtttacaca agggggatct ggataagaga ttaactattg
     3181 atattaaaaa ggcaataatt tataaaattt gtacaaaaaa atgttaaatt ttcacatttt
     3241 catagtatac tgtttagtag aaagtaggtt ctttgtaacc gctccattat aaaatccttt
     3301 cactcttccg gtatactatt aggaaaaaca taactggagg atattttgag ctcacacctc
     3361 atcgttccag tggctgttcc ccaagctcgt gtactgccca aaaaagttag acattctatt
     3421 tagaacgagg attgagttct gtattgtaca aggctcggtc cttttagagt cagcttaagg
     3481 ctggcttttt caatcacaaa agtgtcagaa tgttttgaca aatgaacaca aataatgata
     3541 taatatgcaa aagctaggag gtggtaggat gattgaaaaa atggaactgg gggaatttta
     3601 caaggaatta cgtttggcga gaaagcttaa gcagacagat gtggcttgtg agggtctaac
     3661 agcttctcag ttgtccaagt ttgaactagg gcagtctatg ctgtctgcgg ataagttgat
     3721 tctagctatc caaggtataa atgtgacctt tgatgagttt gggcacaagc tcaacaacta
     3781 tcaagaatct ccacatatgc gaatcggtcg aaaggttgtg aatcgctttg cccatcagga
     3841 tatagctgct ttagagcagc tattggagga agtcgatcaa gaacagatgg cgcagaccta
     3901 tcgtcgtttg aatgccatcg tgattaaaga tgccatccat tcactaaata aaagctaccc
     3961 actagcagag gaggatagcg agtttttgac cacctatctc tatgctatcg agtcttggac
     4021 ctggtttgaa ctctatctct tttgcaatac catgcccttc ttgagcaatc aagatctgat
     4081 ttttttatca acctccttac tcgaaaaatc caaagaattt aaagagttag tacacaatcg
     4141 attgtatatg aagcaaggac tcttaaatat cttatcagaa ctcatggagc gaaaactttt
     4201 ctcctacatc ccaatcttcg aagccgagtt ggagaggatg ttacgaccgt atgatgtttt
     4261 tgaaaaagta tcgtggcaat ttttaaagaa gatgagtgtc tttcttcaaa caaagggaag
     4321 caatcaaaaa gagattgaac gctttatcca atctctgcaa gtattagaaa atccacaatt
     4381 gacagccctt tttgaattgc gtttgcagca atacaaaaag cttatcgatt agttagaaat
     4441 ggcaaaataa taataatctc agcaacgatt ttcaataatg ttaaaatttg tttcttcata
     4501 tttctccact cctcattagt agtaacttta ttataccaga gaagtaatca aattcaccaa
     4561 aatcgcaaat ctgaaatttc tataagaaaa aatatcaaat atgcgatttt ctaaaataag
     4621 ccaattttcg tgttatactg tacttgtaaa gcacttgaag caaatcctag gtcgcagaag
     4681 tggtttacaa atgaagataa ttgaaggagt gtaaaagatg ttaaatttac aatttgcaga
     4741 aacaatggaa ttgacagaag ctgagttgca agatgttaga ggaggcaacc tcgtaaattc
     4801 tatgggaggt ggtggaagaa gtggtatatc tggttggggc gtcccaggaa tttaccctgg
     4861 ttggggcaat caagggatga gtcctaatcg tggagctttt gattggacta tagatttagc
     4921 agatggattg tttggccgcc gtagaagata ggctcttata ggagataata ggatgaagaa
     4981 aatgaaagaa gtgaaatttc acctagcaac tggcttgttg attttgactt attacctcat
     5041 ttttaatgtc acatcagact tagattttat ggttgctttg tctgataata tgtactatgt
     5101 gttccaagtt ttattggtac ttattctggg aactatagct acaattgctt ttgtcaaaag
     5161 tgaacattgg aaagagtgtg gtcgtttcca gtttcgttgg tcttacctgg gtgttttcct
     5221 tctttctttt ttcttattgt tcgtgtgggc aaatctaaca acctatatct ttcctcgtac
     5281 ccagaatgga agtacagtcg tagaagtagc caccaattta acaggaatta gctattttgt
     5341 tacgcgaata ctttatacta gtattatcgc acctgtatca gaagaggttg tttgtcgtgg
     5401 tcttttgatg acaagtttat ctaaagttaa gagatactat cttgatgttc ttgtttccgc
     5461 tgccatattt ggcgctatgc atgttttgca gtatggttgg ataacgacag atttcataaa
     5521 gtattttgga atgggcttga tattttgtat gatgtttcgc tacacccgat ccatctattg
     5581 ggctatagct ctgcatgctt catggaatag tttcttactc attgttactt tattggtatt
     5641 tggatattag aaaggtgata tatgaaaaag ataatctcac accgctactt tattatagtt
     5701 tttctactag ttattgctga ccagaagttc agtgttttag ttttacgcag cgaccttgtt
     5761 gctgggctat ctgactttgc ctattatctg tcggatatga tgttgaattt tcttgtggtt
     5821 ttatttgctc ttattgctat gatttggtcg gggaaatggc agaaaatcaa tagtagaaag
     5881 tttaaaggat cctatctttt ctattccttc ctagctctgc ttgcttttgt tgcttggaat
     5941 tttgtcacct tttttctttt cccacctact cgaaatgaaa tttcttatca acatgctgct
     6001 cctactttta caggagctac ggcatttttg atgtattttt tttatcctgt gattgcaggt
     6061 cccatttttg aagacatgat ttatcgtgga ttagtgatga ctgctctgga aaaaggaaag
     6121 aaatgggggc tagatgtact tggttccgct gttttatttg gggtctcgca cattagtaat
     6181 cacggttggg tcttgacaga ctttgtcttc tatatgggtg gaggtcttat atttgcagtc
     6241 ttatttagaa tgacaaagtc aatttattgg cctattggac tgcatatagt ctacaatggc
     6301 attggtcagc ttttgatgtt actgtaattt tggttgttag tagtatcgcg gtctatcctt
     6361 ggggaaagat tcccatttga acttaagaag gagttgtgat gaaagtattt cttcaaaata
     6421 gagattttag gcaattaact atcaaccagt ggatttcaac gcttggggat acgatttttt
     6481 atctggcctt tctgaattat gtggcagatg cgtcttttgc acctttggcg attttactca
     6541 ttacgatttc agaaaccctt ccccaaattt tacaaatctt tctgggagtt ttggcagatt
     6601 ttcaacatca tcgtgtcttg aaatacacag tcattagttt tgcaaaattt ttgctttact
     6661 ctatcgtttc tttatcactt tcagggcagt ctttctcctt gttgctagta gcatttattt
     6721 gtctgcttaa cctcttgtct gacacattga gttacttttc aggagccatg ctcactccga
     6781 ttttcattag aattattggg caagaccatc tggcagaagc tattggattt aaacagtcaa
     6841 ctgttagttt agtgaaaaca atcagtaata ttctaggagg agtcttgcta gggattctct
     6901 ccatccagtt catttccttg ctgaacgctc ttaccttttt aatcgcattt ttaggtatcc
     6961 tcttcataaa aactgacctc ttgaaagtag aaaaaacgat taactatcaa gaaggactct
     7021 ctgtaaaatc cttttgccag catttgctcc aatcatcgaa attgatatgg aatatgaata
     7081 aggtgctctt ggttttgttt attatctcta ctagtcaagc agtgataaat gttacagttc
     7141 ctgtctctac tctatttttg aggaatcaac cctttttgaa tttacaaaca ggtcaatctc
     7201 ttgccttgct atccactttt gaactgtcag ccctgattgt cggaagcctt gtaagtggct
     7261 atctgcaaca taccatttcc ataaaaacag ctctctatgc ctcacttgtc atccagttgc
     7321 ttcttctagt aggatttgcc acagttcgtt ttgactggat tctcatcttt agtaccttgg
     7381 atgccttttt cgcaggtgtt ctctctccta gattgcaaga gctcgtcttt aaacaaatac
     7441 ctgaggagtc aatgggagca gttcaatcct ctatcggtgc cattacggtt gttttaccta
     7501 gcttatttac aatagctttg gtaaccattg ctactagctt tggaactctg gcagttagct
     7561 ttgttttatt gctatttctt ctagttgcct ttgttatgct tctgaatatt cgtgaaagta
     7621 tttagtggag aatttctata atatatgttt gagactggat tgccagtctt tttatgatgg
     7681 tcaaaatcaa cagacttttt tctcttttct gaatgtgtta taatagactg aatctaaaat
     7741 agtacgaaac aattgctaaa acatttatag aaattaattt tactttccca atcgatttgt
     7801 tctcatctta tttcaatctg ctatataata gtccatgctg tggctggatt cttttcagcc
     7861 tacttatact cttcgaaact ctcttcaaac cacgtcagct tcaccttgcc gtaggtatgg
     7921 ttactgactt cgtcagttct atccacaacc tcaaaacggt gttttgagct gacttcgtca
     7981 gttctatcca caacctcaaa acggtgtttt gagctgactt cgtcagttct atccacaacc
     8041 tcaaaacggt gttttgagct gacttcatca gttctatctg caacctcaaa acagtgtttt
     8101 gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta ttattaagac
     8161 aatatgagga gaaagatgaa agaaaaagga ttttaggagg gggcgcaggc agccatgcca
     8221 acggctcttg gctatgtcag tatcggcctg gcctgtggga ctatcggtgc gccctatgtg
     8281 acacctgttg agatgggctt gatgagtctc tttgtttatg ctgggagtgc ccagtttgcc
     8341 atgttggcac tgattgtggt tcaagctcct gtggcagcta ttgctatgac ggtttttcta
     8401 atcaacttgc gtctcttttt gttgagttta cacgcatcga cttatttccg tcataccagt
     8461 ctttggtaca atatcggtat gtctagtatc ttgacagatg agacctatgg cgttttgatg
     8521 ggtgaattgg cccatacaga caaggtaaat cctatgtgga tgcacggaaa caatcttaac
     8581 agctatgtgg cttggtttgt ggggacagta gtcggaacgg ctctgggtgg cctgctacca
     8641 aatccagaaa tctttggctt ggattttgcc ctggttggga tgtttattgg tatttttgct
     8701 tcgcaatttc agattatgca aagacggatt cctgtccgca atctgctcat tatcctagca
     8761 gttgttgcgg tgtccttctt tttgctcttg acagtggtgt ctcagtcact agctgttctg
     8821 tttgcgacgc tacttggttg tagcatgggg gtggttttag atggtcagta agtatctttt
     8881 attagcagtt attttctctg gcttggtgac ttggattctc cgtatgattc ccttcatctt
     8941 agtcaagtat aagggcttgc ctgcaatcgt tgagcgtttt ttgaagttct tgcccgtttc
     9001 cattatcttt gccttgattc tttcaagcgt agtgacaggt aaggttggga gccttcctca
     9061 aattaaatgg ctagacttct tagccgtctt tccaacagct tgggtagcct ttcgctaccg
     9121 caatctagtc ggaacagttc tctttggagt ggtcttgatt gccatcttgc gtttggtctt
     9181 ttaaattacc cataaaaaaa acttatcaca gagatagata tcatataatg gcgtaaatgc
     9241 tctttttctg ttaagattat aaggtattct attttggagg aaatgacatg aaaaaaatcg
     9301 ttaaatactc atctcttgct gccctaggac ttgttgctgc aggtgtgctt gcggcttgct
     9361 cagggggtgc taagaaagaa ggagaagcag ctagcaagaa agaaatcatc gttgcaacca
     9421 atggatcacc aaggccattt atctatgaag aaaatggcga attgactggt tacgagattg
     9481 aagtcgttcg cgctatcttt aaagattctg acaaatatga tgtcaagttt gaaaagacag
     9541 aatggtcagg tgtctttgct ggtcttgatg ctgaccgtta caatatggct gtcaacaatc
     9601 ttagctacac taaagaacgt gcggagaaat acctctatgc cgcaccaatt gcccaaaatc
     9661 ctaatgtcct tgtcgtgaag aaagatgact ctagtatcaa gtctctcgat gatatcggtg
     9721 gaaaatcgac ggaagtcgtt caagccacta catcagctaa gcagttagaa gcatacaacg
     9781 ctgaacacac ggacaaccca actatcctta actatactaa ggcagatttc caacaaatca
     9841 tggtacgttt gagcgatgga caatttgact ataagatttt tgataaaatc ggtgttgaaa
     9901 cagttatcaa gaaccaaggt ttggacaact tgaaagttat cgaacttcca agcgaccaac
     9961 aaccgtacgt ttacccactt cttgctcaag gtcaagatga gttgaaatca tttgtagaca
    10021 aacgcattaa agaactctac aaagacggaa cgcttgaaaa attgtctaaa caattcttcg
    10081 gagatactta tctaccagca gaggctgata ttaaataatt tcttgaaatc atccattctg
    10141 agtaagatgg gtgatttctc agtttttagg gatatagttt taaactatat atctgattat
    10201 ctaataacaa tttgtgaaat caaacaaatt gtgagatact agtacggtat tatttttaag
    10261 gagaaagaat catgaaaatc aaaaaatggc ttggcctagt agcccttgct acagtcgcag
    10321 gtttggctct tgcagcttgc ggaaactcag aaaagaaagc agacaatgca acaactatca
    10381 aaatcgcaac tgttaaccgt agcggttctg aagaaaaacg ttgggacaaa atccaagaat
    10441 tggttaaaaa agacggaatt accttggaat ttacagagtt cacagactac tcacaaccaa
    10501 acaaagcaac tgctgatggc gaagtagatt tgaacgcttt ccaacactat aacttcttga
    10561 acaactggaa caaagaaaac ggaaaagacc ttgtagcgat tgcagatact tacatctctc
    10621 caatccgcct ttactcaggt ttgaatggaa gtgccaacaa gtacactaaa gtagaagaca
    10681 tcccagcaaa cggagaaatc gctgtaccga atgacgctac aaacgaaagc cgtgcgcttt
    10741 acttgcttca atcagctggc ttgattaaat tggatgtttc tggaactgct cttgcaacag
    10801 ttgccaacat caaagaaaat ccaaagaact tgaaaatcac tgaattggac gctagccaaa
    10861 cagctcgttc attgtcatca gttgacgctg ccgttgtaaa caataccttc gttacagaag
    10921 caaaattgga ctacaagaaa gcacttttca aagaacaagc tgatgaaaac tcaaaacaat
    10981 ggtacaacat cattgttgcg aaaaaagatt gggaaacatc acctaaggct gatgctatca
    11041 agaaagtaat cgcagcttac cacacagatg acgtgaaaaa agttatcgaa gaatcatcag
    11101 acggtttgga tcaaccagtt tggtaataag aaacagggag gtgggagaga gaattccacc
    11161 tcttgctttt gtatagagca cggagtgtaa agaagactat tcgttcatag aaaggtagag
    11221 agaatatggt ttttcctagt gaacaagaac agattgaaaa atttgaaaag gatcatgtag
    11281 cccagcatta ttttgaggtt ttgcgtacct tgatttctaa gaaatcagtc tttgcccagc
    11341 aggttggact caaggaagtc gcaaattatc tgggtgagat tttcaagcgt gttggagctg
    11401 aagtggagat tgatgagagc tatacagcgc cctttgtcat ggcacatttc aagagttcgc
    11461 gtccagatgc caagaccttg attttctata accactatga cactgtgcca gcggatgggg
    11521 atcaggtctg gacagaggat ccttttacgc tttcggtccg caatggcttc atgtatgggc
    11581 gtggagttga tgacgacaag ggtcatatca cagctcgctt gagtgctttg agaaaatata
    11641 tgcagcacca tgatgattta cctgtcaata tcagctttat catggaggga gcggaggaat
    11701 cggcttcaac agacctagat aagtatttgg aaaagcatgc agacaaactc cgtggggcgg
    11761 atttgttggt ctgggaacaa gggaccaaaa atgccttgga acagctggaa atttctggtg
    11821 gcaataaggg gattgtgacc tttgatgcca aggtaaaaag cgctgatgtg gatatccact
    11881 cgagttatgg tggtgttgtg gaatcagctc cttggtatct cctccaagcc ttacagtctc
    11941 ttcgtgctgc ggatggccgt atcttggttg aaggcttgta cgaagaagta caagagccca
    12001 atgaacgaga aatggccttg ctagaaactt atggtcaacg aaacccagag gaagttagtc
    12061 ggatttatgg attggagttg cctctcttac aggaggagcg gatggccttt ctaaaacgtt
    12121 tctttttcga gccagcgctt aatatcgaag gaatccagtc tggttatcaa ggtcagggtg
    12181 ttaagactat tttacctgca gaagccagtg ccaagctaga ggttcgtctg gttccgggcc
    12241 tagaaccgca tgatgttctg gaaaaaattc ggaaacagct agacaaaaat ggctttgata
    12301 aggtagaatt atactatacc ttgggagaga tgagctatcg aagcgatatg agcgcaccag
    12361 ccattctcaa tgtgatcgag ttggccaaga aattctatcc acagggcgtt tcagtcttgc
    12421 cgacgacagc ggggacagga cctatgcata cggtctttga tgccctagag gtaccaatgg
    12481 ttgcattcgg tctaggaaat gccaatagcc gagaccacgg tggagatgaa aatgtgcgaa
    12541 tcgctgatta ttacacccat atcgaattag tagaggagct gattagaagc tatgagtaga
    12601 gatattatca agttagatca gatcgatgtg acttttcacc aaaagaagag aaccattaca
    12661 gcggttaagg atgtgaccat tcacatccaa gaaggggata tctacggaat cgttggatat
    12721 tctggagcag ggaaatcaac ccttgtacgg gtgattaacc tcttgcaaaa accatctgca
    12781 gggaaaatta ccattgacga cgatgtgatt tttgacggca aggtgacctt gacggcagag
    12841 cagttgcgtc gtaaacgtca agatatcggg atgattttcc agcattttaa cctgatgagc
    12901 caaaagacag cagaggagaa tgtagccttt gcccttaaac actctggact cagcaaggaa
    12961 gaaaagaagg ctaaagtagc taagttgttg gacttggttg gtttggcaga tcgtgctgaa
    13021 aactaccctt cacaactatc tggagggcaa aaacagcgtg tggcaattgc gcgtgccttg
    13081 gccaatgatc caaaaatctt gatttcagac gagtcaactt ctgcccttga ccctaagaca
    13141 accaagcaga ttttggcctt gttacaagat ttgaaccaaa aattaggatt gacagttgtc
    13201 ttgattacgc atgaaatgca gattgtcaaa gacattgcca accgtgtggc ggttatgcag
    13261 gatgggcatt tgattgaaga gggaagtgtc cttgaaatct tctcaaaccc taaacaacct
    13321 ttgactcaag actttatctc aacagccaca ggtattgacg aagccatggc caaaatcgag
    13381 aagcaagaaa tcgtggaaca cttgtctgaa aacagtctct tggtgcaact caagtacgct
    13441 ggagcttcaa cagacgagcc acttttgaat gaattgtaca agcattacca agtaatggct
    13501 aatattctct atgggaatat cgaaattctc gatggtactc ctgttggaga attggtggtg
    13561 gtcttgtcag gtgaaaaagc agcgttggca ggtgcccaag aagctattcg ccaagcaggt
    13621 gtacaactaa aagtattgaa gggagtacag taagatggaa tcattgattc aaacctattt
    13681 accaaatgtc tataaaatgg gttgggctgg tcaggcaggc tggggaacgg ctatctactt
    13741 aactctttat atgacagttc tttccttcat tatcggaggc ttcttggggc tagtggcagg
    13801 tctctttctc gtcttgacag cgccaggtgg tgtcttggag aataaagtcg tattctggat
    13861 tttagacaaa attacctcaa tttttcgtgc ggttcccttt atcatcctct tggcaatctt
    13921 gtcaccactt tctcacttga ttgttaaaac aagtatcggg ccaaatgcag cccttgtccc
    13981 actttctttt gcagtctttg ccttctttgc ccgtcaggtg caggttgtct tggctgaatt
    14041 ggatggcggt gtcattgagg cggctcaagc gagcggagcg actttctggg acatcgtggg
    14101 tgtttaccta tcagaaggtc ttccagattt gatccgtgtg acgactgtga ccttgatttc
    14161 ccttgttggg gaaacagcta tggccggtgc ggttggagct ggtggtatcg gtaacgtagc
    14221 catcgcttat ggatttaacc gctacaatca cgatgtgacc atcttggcaa ccatcattat
    14281 cattttgatt atctttgcaa tccaattctt gggagatttc ttgactaaga aattgagcca
    14341 taaataaaaa agagccgcgt ggctcttttt aactgatcag attttctgtg caaatttttt
    14401 actcaaggct tgtccaatca aggcacccac tagggctccg atgacaatac ttgcgataaa
    14461 tagaaggaca gttccagggg ttggagcgac catgatacgg tcgatatatt cttgggattt
    14521 tcctcttgcc agaagagtag ccatataggc tttgggcgca atccacataa gcaagattgg
    14581 tcctgttgta ctaaaggcga aaataatgaa agaaaggaag ttctttgttt tgtccttgta
    14641 ttttcctaaa tgagctactc catctgctag gaggccacag ataattccag gaaggaagga
    14701 accagcaccg tgtttagttc ccaagaaaaa gagggcaatg acaaggccga tagtggtaat
    14761 ggctccaaag cgcggaactt ttgcgactag gatcatatag acgctaccgc cgacaagggc
    14821 agtaaaggca ggcgcataaa acatgtttcc agtttggtca aagagattgc ccaaaaggac
    14881 accaatcccc atgcagagga agtaaagaac tgcaaaaagc agtgtagtta agatagattt
    14941 cttcatgaat tgtctcctga taattttttc acaattctca ttttaccatg gtttggtggg
    15001 attgtaaatg gatactagaa gtttttgaaa acgcttgaaa tatgatataa tggtttcata
    15061 gttattttta ggggaatatc atgggtagat ttttagactt tgtctttaat cgtttctttt
    15121 tagggatgat tgcgacagcc ttcttttggc tattaacttt agcaggaggg attatccttg
    15181 gtctagcgcc ggctagtgcc accttgatga gcttatatgc agaacatggt tatagctttc
    15241 gggaatacag tttgaaggag gcttggtctc tttacaagca aaattttgtc tcaagcaacc
    15301 tgattttcta tagcttttta ggtgtgggtc tagttttgac ctatggtttg tatctcttgg
    15361 tgcaattgcc tcatcagacc attgttcatt tgattgcgac ccttttgaat gtcctagtag
    15421 ttgccctgat ctttttggct tatacagtat ctttaaaatt acaagtttat tttgccttgt
    15481 cctatcgaaa tagtctcaaa ttatccttga ttggcatctt tatgagtcta gcagctgtgg
    15541 ccaaggttct ccttgggact gtgctacttg tagcaattgg ttactatatg cctgccctgc
    15601 tattttttgt aggaattggg atgtggcatt tctttatcag tgatatgttg gaacctgtct
    15661 atgaaatcat ccatgaaaaa ttggcgacaa aatagaatga agcagttttg gctacatacg
    15721 cttctaagaa cctatagttc agtgatgatc attatcattg cgagttttgc aatcttactc
    15781 tcttacgctg actgggattc acgtgaaaag gaagcccaga gagtagccca gcgtgtaact
    15841 gctagaacag tgagtgaaat tgaatattac catagagagt caacccagat agctcaggct
    15901 ttagttgaaa atcaagctcg tattgaggga atctataaat actttagcct tagcatgcca
    15961 gactattttt actggcaatt agagcggaaa gcttcgcctt atatatcagt ctctctgtat
    16021 gaaaatgttg atgacctcta tgttcgaaat gattttgtaa ctggagtggc cattgctttt
    16081 caagattaca aggaagtcta tgtttctact aaagacaaac gtagtggaga aaaaatcagg
    16141 gctgaggatt tcaaaccagc aggaaatagt tttgccattc cagtgtcaga tccagtgtca
    16201 gatcaagact taggagtgat ttacatctcc ttggatcctg ctgttttata ccatgccatt
    16261 gataatacta gaggtcatac tccgatggca gtaacagtga cctcaccttt tgatacggag
    16321 atttttcata tgggtgagac agttgataag gagagtgaaa attggctagt tggcttaact
    16381 tctcatggtt atcaggttca ggtggcagtt cccaaaaact ttgttttaca aggaacggtg
    16441 accagctctg ctttgattgt gggcttgagc cttctcttta ttgtcattct ttatctgact
    16501 ttgaggcaga cctttgctaa ttatcaaaag caggtagtgg atttggtgga ttccatccaa
    16561 gctattgccc aaggacaaga aggtcttcgc attgatacgc ttgaaaagga tcaggaattg
    16621 ctcctaatcg cggagacgac caatgatatg ttggatcgat tggaaaagaa tatccatgat
    16681 atttaccagt tagaactcag tcaaaaagat gccaatatgc gggccttgca ggcgcaaatc
    16741 aaccctcact tcatgtataa tacgctggag ttcttgcgta tgtacgcagt catgcagagt
    16801 caagatgagt tggcagatat catttatgaa ttcagtagtc tcttgcgtaa caatatttcc
    16861 gacgaaagag agaccctcct caaacaggaa ttagaatttt gccgtaaata cagctatctc
    16921 tgcatggttc gctatcccaa gtccattgcc tatggtttca agatagatcc agagttagag
    16981 aatatgaaga ttcccaagtt taccttgcaa ccgctggtag aaaactattt cgcgcatggt
    17041 gttgaccaca ggcggacaga taatgtgatt agcatcaagg ctcttaaaca ggatgggttt
    17101 gtggaaattt tggtggtcga taatggtaga ggaatgtcgg ctgaaaagtt ggcaaatatc
    17161 cgagaaaaat taagtcagaa atattttgaa caccaagcca gctacagtga tcaaaggcag
    17221 tctatcggga ttgtcaatgt acacgagcgt tttgtgctct attttggaga ccgctatgcc
    17281 attactatag agtctgcaga gcaagccggt gttcagtatc gtattacaat tcaagatgag
    17341 tagaaaggga gaaaatgtat aaagtattat tagtagatga tgagtacatg gtgacagaag
    17401 gtctgaagcg tttgattccc tttgataagt gggatatgga ggtcgtcgca acagccagtc
    17461 atgccgatga agctctagaa tatgttcagg aaaatcctgt cgatgtcatc atttccgatg
    17521 tcaatatgcc agacaaaaca gggcttgata tgattcggga gatgaaagag atcttaccag
    17581 atgctgccta tatcctgctc tcaggttatc aggagtttga ttatgtaaaa agagcaatga
    17641 accttagtgt ggtggactat ttggtcaagc ctgttgataa ggtagagctg ggaaatctgc
    17701 tggagaagat tgcaggtcag ctcggcgaga gagggaagaa aagtcagact cttagtcaag
    17761 aattagacga ggctggattt gttagttatt taggggataa ggagaattgg tggataggtc
    17821 tatccaagga aaaacaaggt tccttcacca ttccctacta tgtcttgggc caagactggc
    17881 agattttcat ttctgaccaa cccctagatg gtttagtcgt tacacctttt gaagctcctt
    17941 atcaagaaca ctttgaacgc tggaagctga atgctgagaa aaccctcttt tacggttctg
    18001 taaatttgca gcagtctgag agtctctttg cctattacga accgatttat agggttatta
    18061 ttcagggaaa tctcaatcaa atcgtagaag agttaaatct cttggagaag gtagttcttg
    18121 aaaatacgcc gcgtgttccg attactaaac agctttttat tcagtttgtc atggatgttt
    18181 tccatttatt tgaacatctc aaagctgatg acctgacaga catcgtcaaa accattcatg
    18241 ctattcaatc cttcgatgaa ttggttcctt atatcaagga aactctgagc agctttttcg
    18301 gtcaataccg tatgaatgaa aatgtggtca gtgtgctgga agtcattggt cgtgattacc
    18361 aaaaagagct ttccctcaag gatatcagta aggctctctt tatcaatcct gtctatctag
    18421 ggcagttgat taagcgtgaa accgattcga cttttgcaga gttactaaac aaacaacgta
    18481 ttaaggctgc ccaacaactt ttgctttcaa ctagtgacag catcgaagat atttgttatg
    18541 ctgttggtta cagtaacctt ggatatttct ataaagtttt ccgaaaattg tgcggaaaat
    18601 cgccaaaagc ctaccgaaaa caggtagaaa ctatactata agatttgtat tcctttacaa
    18661 aaggtgctat aatattatca ggaggtccta tcatgaaaaa gaaaccaatt tatctatggg
    18721 tcttgctaat cttgtctgcc cttatttcag ttccgtctct gtttggaatt gtgagtccct
    18781 tgcctagtaa agaagccctt cgtgctgctc agaaacaagt tgcaggggtc aatgctcagc
    18841 aattagaaga ccagcttaat tatacctata gagtagcaga agcatctcat tctattttta
    18901 atgttgcttt gattgtgcta tctactattt tagtggtcgt agcgattgtc ttccttgttc
    18961 gtaaaaattt gcaatatgca aactatactt acgttggcta tgttttgtta gctattattg
    19021 gttcgattta tggctatgtt ggtttacaag acgctgtgca gttggttcaa gatgagagca
    19081 tgcgtttgac agtgagtatt ggctcaaaag ctgttagcat tttctatatc gtcatcaatg
    19141 ttctcttcct agcccttgtc ttctataaga tgtggcgaca acagaaagcc ttggcagaag
    19201 aagaggaaac agaagagctt acctaagtat tgacaaaaaa gaactatcaa gatacaatct
    19261 tggtagttgt tttttgatta tagataaaat catggaggta catatgaaga caatttcttt
    19321 agtttatatt agtttgagtg gcaacactga aagttttgtg acgcgcttga aagactatct
    19381 cttgtcccag tacaaaggga ttgaggttca aaagattcat atcaaggatt tggtcaagga
    19441 aggcaaaaat ttctatgaaa tggaccatcc ctatgtcgct tttttgccga cctatctcga
    19501 aggtgggaat ggcgtggata acggagatgt tgagattttg acgacaccgg tgggagattt
    19561 tattgcctat ggtaacaatg ctagtaagtg ttttggtgtg gttgggtcag gaaatcgtaa
    19621 ctttaataac caatactgcc taacagccaa gcaatacagt caacgctttg gcttccctgt
    19681 attggctgac tttgaaatgc gaggcatgct ggaagatatc aaacatgtcg cagctattat
    19741 cgcagatttg tatgagttgg aaaaggagaa ttaatactca atgaaaatca aagagcaaac
    19801 taggaagcta gtcgcaggtt gctcaaagca cagctttgag gttgcagata gagctgacgt
    19861 ggtttgaaga gattctcgaa tagtataaag ttcttataag aggtggttga agttgttcaa
    19921 ctgttttttg agtataaaca gtctttaaga acgtaaaaaa gcataagttc aggtcttcaa
    19981 aaccttgttc ttatgctttt tatcatagaa atatttgctg aattttctct tgaaatgaaa
    20041 ccttatcttc atctcgcgct tgtcccttac cctgcttttc cgattgcgag tgcgtagata
    20101 aagaagatgg cgaagccaaa gaggaaaatc aatcccgcaa tggcaaggtg tttgagccaa
    20161 gaaggaagat ttttgttttc acgtgttacc aaggcgtaat tcaaaagagc aaagaaaggt
    20221 gttgtcagga aagagccaat catggcaaag cggagcatgg ttgaaacctg accagcgaag
    20281 aacttgataa tgacgatacc gatgatagca gtgatggtca tccagatgtt caaagattta
    20341 cgattgtcct ctttttgact gattagcagt cggagagatt cctgattaac gcgagaatag
    20401 ccatcgataa cagttataac tgttccaaag atacagagga aggcaataaa ggtaatcaag
    20461 taacgggacc attcgccaag aacagaggca tacatgccca cgaattgaga gatgtatttg
    20521 gctgaagcag cttcaaccgc ctgccctgta ggatactgaa tcagtgctcc cagtgccaca
    20581 aagaagacgg ctaggatagc tgttccaata taaccagtgt taaagtcaaa cagagcgtct
    20641 tctgtgttaa agttgacggt ctttctcttt tcagctgacc aaagtgaatt gatggctgaa
    20701 atttcaatag gagccggcat ccatcctagg agggagacga tgaagggcag agctgccatt
    20761 tgccaaggtg tcttctcgac aaaatcagaa ctgtattctg gatgcttgac cgccgcaatg
    20821 ataactgcaa gaacagtcgc aatggttaag gcagacataa tccatttgac catgccgtct
    20881 aaaagtttgt agcctccaaa gagtagcata gcccaaatga ttgcaacgag aatgagggac
    20941 cactgagtaa tgctaagtcc aatcattggg aaggcactgg cgatgatagc tgagcacaga
    21001 atggcaacac cagccgtgtt gaccatagcc gaaaagacat tgagaataaa gaaaatccag
    21061 agatagagtt ttcctttttc ggcataacct tcaaccaaag tctttccagt atcagctgtg
    21121 tattcagcac caaaacggaa aaatggatat ttaaagacat tggctaagat gaccaagaga
    21181 agtagagacc aaccgtaaga accgccagct tgagttgagg atacaatgtg ggaacctcca
    21241 acagcggcag ttgccattag gattccaggt cccattgctt ttagcttgct tgcccaggtt
    21301 gattgattta aggaaatagc ttgcgacatg ataaatactc ctttttgaat tttcagaata
    21361 atctgtatat gcaatctata ttctacaaaa aattttggaa aaatgcaaga atattttgaa
    21421 aaaagataga aaatttacaa agaaaatctg aaataactgt tatgatatag cagattgaaa
    21481 ctagaatagt acacttttgc ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatt
    21541 gatttatcct gttcttattt catttcacta tagtaaggtg cagcaggata aagcaaaacc
    21601 gagaagtttc tttctcggtt ttgcttatta tgaggttcct attttctatg ctccaagagt
    21661 tgattgatgt gatctacttt tttagcctct cttttataga gaatagccca gatgatgaga
    21721 tagacaatcg caaactcgat aatgagctgg aggtagaaaa tccagtggaa ggggaaccaa
    21781 ccagcaagag ttgctagtgg gacaaagcca gccagcataa ggaagaaatg agtcagagtg
    21841 gcacgaagca tgctccagtc acggctgaat aagcggttgc caaagttgaa gagcataccg
    21901 atggctgccc agataagtgt gcagtagagc aagaccaggg caccgtgaac ctgatgctga
    21961 tccatcactt ggccgatgag agagtaggga tttagtggtg cgtaggtatt tggtgcataa
    22021 atgagtgaaa agaggatgga gaggatgagg ccgataagaa caccggcagc tgcatcgtga
    22081 aatacttgtt ttttcatagt tctaatttct ccttgatggt ttttagataa cggcgtgaag
    22141 agtaggtgaa gctttcgttt ttcaagaaaa tttctaccag accgtttggc gtgagcttga
    22201 ggtgagagat ggaatcgata ttgatgattt ctgattggga aatttggata aaattgcttg
    22261 gcaagagttt aagaacctga tagagtcgca aatcaatgct gtaggtctga ctcgcggttt
    22321 ctgctagaac cttccgattc tcgatataga agcgctgaat cttgccaatc tcaactagat
    22381 agacctgatc atcgattttt cctttgattt tttctctttg gtccagattt tctgcgaact
    22441 cgatgacttt ctggactttt tcggtttctt gaggtgcttg gacaatcagc ttttcctcct
    22501 cgtaagtctc actaatctgt agttctactt tcatagtttt ctctcctttt cagttataca
    22561 aggttgtgat cacttcctgt atatccttat taaacactat tttatagccc atggcaagga
    22621 accttgtcta tgtggaggga ttgggctcct atgtggtgga gcttttctgt tctttctgaa
    22681 atatggtata atagcactaa ttaatttcta ggaaaataga tacagaaagg ggctgaaaga
    22741 tgtctcatat tattgaattg ccagagatgc tggcaaacca aatcgcagct ggagaggtca
    22801 ttgaacgtcc tgccagtgtg gtcaaagagt tggtagaaaa tgccattgac gcgggctcta
    22861 gtcagattat cattgagatt gaggaagctg gtctcaagaa ggttcaaatc acggataacg
    22921 gtcatggaat tgcccacgat gaggtggagt tggccctgcg tcgccatgcg accagtaaga
    22981 taaaaaatca agcagatctc tttcggattc ggacgcttgg ttttcgtggt gaagccttgc
    23041 cttctattgc gtctgttagt gtcttgactc tgttaacggc ggtggatggt gctagtcatg
    23101 gaaccaagtt agtcgcgcgt gggggtgaag ttgaggaagt catcccagcg actagtcctg
    23161 tgggaaccaa ggtttgtgtg gaggatctct ttttcaacac gcctgcccgt ctcaagtata
    23221 tgaagagcca gcaagcggag ttgtctcata tcattgatat tgtcaaccgt ctgggcttgg
    23281 cccatcctga gatttctttt agcttgatta gtgatggcaa ggaaatgacg cggacagcag
    23341 ggactggtca actgcgccaa gcaatcgcag ggatttacgg tttggtcagt gccaagaaga
    23401 tgattgaaat tgagaactct gacctagatt tcgaaatttc aggttttgtg tctttacctg
    23461 agttgactcg ggctaaccgc aattatatca gcctcttcat caatggccgt tatatcaaga
    23521 acttcctgct aaatcgtgct attttggatg gtttcggaag caagcttatg gttggacgtt
    23581 ttccactggc tgtcattcac atccatatcg acccttatct agcggatgtc aatgtgcatc
    23641 caactaagca agaggtgcgg atttccaagg aaaaagaact gatgaccctg gtttcagaag
    23701 ctattgcaaa tagtctcaag gaacaaacct tgattccaga tgccttggaa aatcttgcca
    23761 aatcgaccgt gcgcaatcgt gagaaggtgg agcaaactat tctcccactc aaagaaaata
    23821 cgctctacta tgagaaaact gagccgtcaa gacctagtca aactgaagta gctgattatc
    23881 aggtagaatt gactgatgaa gggcaggatt tgaccctgtt tgccaaggaa accttggacc
    23941 gattgaccaa gccagcaaaa ctgcattttg cagagagaaa gcctgctaac tacgaccagc
    24001 tagaccatcc agagttagat cttgctagca tcgataaggc ttatgacaaa ctggagcgag
    24061 aagaagcatc cagcttccca gagttggagt ttttcggaca aatgcacggg acttatctct
    24121 ttgcccaagg gcgagatgga ctttacatca tagatcagca cgctgctcag gaacgggtca
    24181 agtacgagga gtaccgtgaa agcattggca atgttgacca gagccagcag caactcctag
    24241 tgccctatat ctttgaattt cctgcggatg atgccctgcg tctcaaggaa agaatgcctc
    24301 tcttagagga agtgggcgtc tttctagcag agtacggaga aaatcaattt attctacgtg
    24361 aacatcctat ttggatggca gaagaagaga ttgaatcagg catctatgag atgtgcgaca
    24421 tgctcctttt gaccaaggaa gtttctatca agaaataccg agcagagctg gctatcatga
    24481 tgtcttgcaa gcgatctatc aaggccaatc atcgtattga tgatcattca gctagacaac
    24541 tcctctatca gctttctcaa tgtgacaatc cctataactg tcctcacgga cgtcctgttt
    24601 tggtgcattt taccaagtcg gatatggaaa agatgttccg acgtattcag gaaaatcaca
    24661 ccagtctccg tgagttgggg aaatattaaa agtataaaaa agtctgggaa aaattttcaa
    24721 aatcaaaaaa acgcataaaa tcaggtgttc aaaaaccttg attttatgcg ttttatcatg
    24781 gaaatagtta cttcattttt tcctaattct tttcgaaact ctttttaaac gacgtcagtt
    24841 ttatcagtaa tctcaaaaca gtgttttgag ctaattttgc cagttttgtc tgtaacatcg
    24901 aagttgtgtt ttaccactct gcgactggtt tcctagtttg ctctatgatt ttcacagagt
    24961 attaaattgc gattttgcca agtttcttta ttcgtctaaa agtagagtct gttctatgcg
    25021 tctaatgtac gaattaggtt gaccatttca atagctcctt gtgcacactc agaaccctta
    25081 tttcctgctt tagtaccagc tcgttctatg gcttgttcaa ttgtatctgt cgttagcaca
    25141 ccaaacataa caggaatttc gctatttaaa ctgatttggg cgattccctt agatacctcg
    25201 ctacatacat aatcataatg acttgtattt cctctaatga cagctcccaa gcagataatt
    25261 gcatcatatt ttttactttt tgccattttt gatgcaatca gtgatatttc aaaagctcct
    25321 ggaacccagg ctacctcgat atctttctcg tttacattct ctcttttgag attatctagt
    25381 gctccagata ataattttga agttataaat tcattaaatc tcgctacaac aatacctatt
    25441 ttaatattgt ttgctactaa attaccttca taagtgttca tttatttttc ctccatattt
    25501 aaaatgtgac ccattcgatt tttctttgtt tctaaataaa aactatcgta aggattggct
    25561 tctatttcga ttgatattct actggaaatg gtaattccat atttttctaa ctgttcaacc
    25621 ttgtcaggat tatttgtcag taaatgaagt gactgaagtc ccagatcttt aagcatttgt
    25681 gctccaatat gatattctct taaatcacct tcaaagccta atgcaagatt ggcatcaagc
    25741 gtatccatgc cttgatcttg taaatgatag gcttttaatt tattgataag tccaattcct
    25801 cgtccctcct gtcgcaagta aagtaagaca cccgaaccat tctcaacaat cattttcata
    25861 gctttatcga attgctgtcc acaatcgcaa cgtaaggagc ctaaaacatc ccctgttaaa
    25921 cattcggagt ggacccgaca taatacattg gcttcatcct ctatgtttcc cataataaga
    25981 gcaagatgat gttccccatt tagtttatct atatagctaa ttgctttgaa attaccgtat
    26041 ctagtaggca tattgacagt tgaaactcgt tctaccagct gatcatatac ttttctatat
    26101 tcttgtaatt ctttgatggt aattagtgga atgttgtgtt tcttcgagaa ctgaattaaa
    26161 tcatctgttc tcatcatttt gccatcatga ttcattattt cacaacatag gccacactct
    26221 tttagtccag ctaattttaa taaatcaaca gttgcttctg tgtgtccatt tctttctaga
    26281 acaccacctt tttttgcaat taaaggaaac atgtgtcctg gcctgcgaaa atcagagggt
    26341 gttatatctt cagctacaca catacgtgcg gtcagtcctc tttcctcggc agaaatacct
    26401 gtggtcgttt ctttataatc aattgaaact gtaaaagcag tcttatgatt atctgtattg
    26461 ttttcaacca taggtgaaag cattaattga ttagctaaac tttcgctcat aggcatacaa
    26521 attaatcctt tggcataagt agccataaaa ttaacatttt ctgttgtagc tgcttgtgca
    26581 gaacaaatta agtctccttc attttctcta tccttgtcgt ctataacaag aacaagtcgt
    26641 cccttctgca atgcttctaa tgcttcttgt atttttcgat attccattga ctgattatcc
    26701 tttctgctaa aatccatttt gatataatag ttccttagat atttctgatt ttggagagtt
    26761 atccatcagt ttttgcacat atttacctaa gatatcattt tcaagattta ctgtactccc
    26821 gacttgttta ctcttaagaa tggtttgttc caaggtatga gggataacag atactgaaaa
    26881 gtttactttg gagactttag cgacagtcag actaatgccg tcaattgtaa tagatccttt
    26941 ttcaactatt aaatctaaaa tttctttttg tgtgttgatt tgataccata cagcattatc
    27001 atcttttttt attgacgaga tttttcctgt accatcaatg tgtcctgtaa cgacgtgacc
    27061 cccaagtcga ccgttgacag ataaggctct ttctagattc acctcacttc catgttttaa
    27121 tagagtaaga gctgttcgac tccatgtttc attcattaca tcaactgtaa aggattgatg
    27181 attgaaatga gtaactgtaa gacagatacc atttactgct atactatcgc ctaaatggat
    27241 atccgttaat atttttgagg ctttaattga tagtttacaa ttacgagagt ctttctgtat
    27301 tctttcaact tttccgattt cttcaattat tcctgtgaac atggataaat cacttcactt
    27361 tctatgagat agtcatttcc tatttgagaa aatgcataag gtttcaatct aatagcgcca
    27421 tttggcaaag aaataccttc acctccgaca ggaaacttgg cactacctcc aaaaattttt
    27481 ggtgcaatat atattttcag ctcatcaaca atttgttgtt ccaaagcact ccaattcatt
    27541 agactgcccc cttctagaac taggctatca atctgcatgt ttcctagatg ttgcattaaa
    27601 ctcgataagt ctatatgatt gccttttttc tttatggaaa gtatttcaca gccatgattt
    27661 tgatatagct tcattttatt tttgtcttca gaggaagtgg caatgtaagt tttaatatca
    27721 tttgctgttt ttacgatttt agaggtaaga ggagttcgta aatgtgtatc gcatatgata
    27781 cggataggat ttttcccttc ctccaatcta catgtcagca aaggatcgtc ttgaataaca
    27841 gtattgactc ccaccataat tgcactaaca tagtgtcgta actgatgcac atgctttctt
    27901 gcttcttctt cagtaatcca tttggattga tttgttttag tggctatttt tccatccatt
    27961 gacattgcat atttcataaa aacatagggt acatgctggg taatatactt tctaaaactt
    28021 tttattaagt taagacactc attttctaaa attccaacag taacttgaag attattttcc
    28081 tcaagtatct ttactccttt tccagataca ataggattac agtctaggct tccaatgact
    28141 actcttgtaa taccactatc gattatagca tctatacagg gaggtgtttt cccgaagtga
    28201 caacagggtt caagtgttac ataaagcgtc gctccgacag gggattttct acagttttta
    28261 agagcatttc tctcagcatg tgggccacca aaaaactcat gataaccttg tccgatgatg
    28321 tgattatctt ttacaataac tgcgccgacc ataggattgg gattgacgta accagcccct
    28381 ttttgtgcca gttttattgc taatttcata tattttgaat cgctcatctc actacctcca
    28441 aaaaaaatat accttgaata ggggactact caaggcatac aaaagaaaac ttatacgatt
    28501 aacaaaaata ctctgaaatg acaagtaatc atttcagagc acgcaaaaag cacaaatata
    28561 cttttatctt ctttcatcca gactatactg tcggctttgg aatttcacca aatcatgcct
    28621 ttcggctcgt gggctatacc accggtaggg aattgcaccc tgccctgaag atagttattc
    28681 aattacagat gattatagta cttaattttg aatatgtcaa cagataaata ccgattgttt
    28741 ttgatatact gtatttgtga taatcgattc tcgctcctcg gataaagaaa atatgatata
    28801 ctagataaac gaaataagag agaaggaata ctatgtacgc atatttaaaa ggaatcatta
    28861 ccaaaattac tgccaaatac attgttcttg aaaccaatgg tattggttat atcctgcatg
    28921 tggccaatcc ttatgcctat tcaggtcagg ttaatcagga ggctcagatt tatgtgcatc
    28981 aggttgtgcg tgaggacgcc catttgcttt atggatttcg ctcagaggat gagaaaaagc
    29041 tctttcttag tctgatttcg gtctctggga ttggtcctgt atcagctctt gctattatcg
    29101 ctgctgatga caatgctggc ttggttcaag ccattgaaac caagaacatc acctacttga
    29161 ccaagttccc taaaattggc aagaaaacag cccagcagat ggtgctggac ttggaaggca
    29221 aggtagtagt tgcaggagat ggccttcctg ccaaggtcgc agtgcaagca agtgttgaaa
    29281 accaagaatt ggaagaagct atggaagcca tgttggctct gggctacaag gcaacagagc
    29341 tcaagaaaat caagaaattc tttgaaggaa cgacagatac agctgagaac tatatcaagt
    29401 cggcccttaa aatgttggtc aaataggagc agagaatgac aaaacgttgt tcgtgggtca
    29461 agatgaccaa cccactctac atcgcctatc atgatgagga gtggggccag cccctccatg
    29521 atgaccaagc gttgtttgag ttgttgtgta tggaaaccta tcaggcaggc ctgtcttggg
    29581 aaacggtact caacaaacgc caagctttcc gagaagcctt tcatagctat caaattcact
    29641 cagtcgcaga gatgactgac actgaattgg aagccatgct ggagaatcca gctatcattc
    29701 gaaatagagc caagattttt gctacacgcg ctaacgccca agcttttcta cagttacagg
    29761 cagagtacgg ctcttttgat gcctatcttt ggtcttttgt tgaggggaaa actgtcgtta
    29821 acgatgttcc tgattatcgc caagccccag ttaaaacacc cttatctgag aaattagcca
    29881 aagatctcaa aaaacgaggc ttcaagttca caggcccagt cgccgtattg tcttttctac
    29941 aggctgcagg gctagttgat gaccacgaga atgattgtga gtggaaaggt cttaaatgat
    30001 gtctaacaaa aataaggaaa ttctgatttt tgcgattctc tatacagtcc tctttgtgtt
    30061 tgatggcgtt aaattgctgg cttctttaat gccatctacc attgcaaatt atcttgttta
    30121 tgtagtttta gctttatatg gctccttctt gttcaaggat agattgatcc aataatggaa
    30181 ggagattaga aagactaaaa gaaaattctt ctttggagtc ttaacaggat ggctctttct
    30241 cattctgatg actgttgtct ttgaatttgt atcagagatg ttgaagcagt ttgtgggact
    30301 agatggacaa ggtctaaatc agtctaatat tcaaagtacc tttcaagaac aaccactact
    30361 gatagctgtt tttgcttgtg tcattggacc tctgatagaa gaattatttt tccgtcaggt
    30421 cttattgcat tacttgcagg aacggttgcc aggtttacta agcattattc tggtaggact
    30481 tgtttttgct ctgactcata tgcacagttt ggctctatca gagtggattg gtgcagttgg
    30541 ttacttaggt ggaggccttg ccttttctat tatttatgtg aaagaaaaag aaaatatcta
    30601 ctatccccta cttgttcaca tgttaagcaa cagcctctcc ttaatcattt tagttatcag
    30661 tatagtaaaa tgaaataaga acaggacagt caaatcgatt tctaacaatg ctttagaagt
    30721 agaggtgtac tattctagtt tcaatacact gtaacatgtg atgaaaatgc cagtaatgat
    30781 accgagaaaa aagctgagaa acttttccca gctttatttg ttatagtcaa agcgaatgac
    30841 ttgttcctgt gcatctacat gagcatggac cccaaagggt acaattgctc ttggagttgc
    30901 gtggccgaca ttcagattat agacaatcgg gatattgttg tcaatgatat ccaatagtgc
    30961 ctctttatag tcgtcatgga aaatttcatc cataggtttt ccgaccaaga gtccattgat
    31021 gaccgcgaat atgccagtgt cctttaaagt tagcaacatc tttttgaagt cttctggctt
    31081 aggctcttct tcgcttgttt cgagcaagag gattttccct tcccagtctg acaagtcagg
    31141 gaaaagtttg tatttttggc agagttccgt gctatctgcg tatcgagagt tgtcaaagat
    31201 atcgtagagg gattcgaggc aaccaccgag gattttcccc tcgaactggg cacttccttg
    31261 caacaagtca aaacctgtat ttgtatgact gacacgaggt gttcccaggg ccgtgggact
    31321 aaaatcagtt cgttcctcat accaaacgtc actagggcgg atttctgaaa ttcttcccgt
    31381 ctcaatcaat tctttaaagt agtgaaggct ataggctagc atttctttgt ctaattcaca
    31441 aatgtctgct aaaaaggatt gaccataaaa agtcttgatt cctaatttat gcaacatgag
    31501 gtggttcatg gttgtatccg agaagccaag aaaaattttt tgtttgataa ccttttggag
    31561 ttggtcattt tcaaaaagat aaggtagcaa gcgataggta tcgtctccac cgatggcaca
    31621 taggatcatg tcgatgctat catcagaaaa ggcatgaatc aaatcctctg cacgagcttc
    31681 aggatggtcc ttgataaagt ctaatccttt taacgaatgg ggcaaaaaga tgggattgag
    31741 tcccagatcc ttgagacgtt ggatacccaa gtccacttcg tgtttgacaa aatcctctcc
    31801 gataatgcca ctagataaac taacaatacc aatagtagaa accatatctc atcctcctag
    31861 aaatagattg agcctatttt atcacaaaat ataagagaaa gctatgtggg atttcagaag
    31921 aatactttta atactcttcg aaaatctctt caaaccacgt cagttttatc tgcaacctca
    31981 aagctgtgct ttgagcaacc tgcagctagc ttcctagttt gctctttgat tttcattgag
    32041 tataactcaa aaaagtaagt gaaaaagcaa ccgcacctgc agttgctttt atcgttttct
    32101 tattcttgat agcgtgttgg tcctgcactt gcactacgga tattcaagcg tttcttgaga
    32161 tagaagcgaa gggctaggag ggctgctcca ataatagcta gtggcaatgg atccagtact
    32221 gggttaaggc tagctggtag gaagcttgtt gcaaagaaga caagcaacca aaggaacata
    32281 gaagctagga taactagtac agatttccag aaaggtggac gttgactgcg atccatatct
    32341 ggtccatagt attggtaaac aaagtagtac atcaagtaga aggcaaatcc accaaccagt
    32401 ccaactaata gaagagtaat caatccatag ccgaaagctt gatctgccgc aaagaaggtt
    32461 gtgagggcgc tgacaagggc aaagaggcta gtgatgaaaa gagctgagtc cataatcatc
    32521 agttttggat catcattttc ttttggatgc tctttttcgt actgctcttt gacagtgaag
    32581 ctatgagccc aatgagttgg tgcgccgtat agggaacggg cagttgtacc tttagattgc
    32641 tcctcaagga tgtggggaat gacttcctca aaaatagtct ggatttcagc gtctgttttc
    32701 ccatctttga tgaattgttg ggtagcaatg tggacaaact cttggttttt cttagttaat
    32761 ttttgtagat caatttgaga cataggaact cctcttagaa ccatttttta tggatgagat
    32821 agagagtgag cgagacactc atagcaaagg cgataaagac gattaaccag aaggcatttg
    32881 gctctccgtt tagggggatt tcattatcct taaagttcat cccgtaggca gaaaagacca
    32941 tggttgggat ggacatgacg atggtcacaa gggccaaggt tttcatgatg ttgttctggt
    33001 tgttagaaat gatagaggca aaggtctctg tcatagaatg caagacgttt ccataaatat
    33061 ctgccatctc gatggcctgt tgggtttcaa tcagggtgtc ttcaagcagg tcttcgtcct
    33121 caaggtattt cttgatattg ctggttgaac tggtcaattt cttaatcacg cgctcatttg
    33181 ttttgaggga ggccttgaaa tagacgatag ttttttccaa ttccatgagc tcaatcaatt
    33241 cttcattacg agttgattga tgcagttgac tttcgatttg ttcactcttg cggtcgattg
    33301 aacgaagggc tgttaggtaa agctctgcat tgcgataaag aatttgaaag ataaaacgtg
    33361 aacgcatgaa ggtatagaaa ttacgcaatc gacggttgat aaagacatca aggacaggta
    33421 gtggttccaa acacgtagtg ataatggttt cctcagtgat gataatacca agcgggatgg
    33481 ttacgtagta ggtgcggtta tttctttcct ccgtgaccgg cacgtctacg ataatcaggg
    33541 tatactcgtc ttcaatggta atacgagaca tttcttccgc atcgagcggt gctcgaaggt
    33601 cggcaatatc aatatcgaag gtgttggcga tttcgagtga ttcattttga gtcggattga
    33661 cgagattgat ccaagtaccc ggttcaagcg tatcgatctc tttaaattca gttgttgtag
    33721 agagaaaaac ttgtttcata tcccttatcc tttctcattt ttcagatttt ttcacactgt
    33781 actattatac tacaaaatcg gccttttggg taatagaatc tcactttttt tggtataatg
    33841 gtaagcaata atggactaga aagaacaaag atgcaagata aaattgtcat tcatggggcg
    33901 cgtgcccata atttaaaaaa tattgatgtg gagattccgc gagacaagtt ggttgtcgtg
    33961 actggcttgt caggttcagg gaagtccagt ctggcttttg ataccctcta tgcggaggga
    34021 caacgtcgct atgtagagag tttgtccgcc tacgctcgtc agttcttggg aaatatggaa
    34081 aaaccagatg tagatgccat tgatggtctc agcccagcta tttccatcga ccagaaaacg
    34141 actagtaaaa atcctcgctc gacggtggga acgacgactg aaatcaatga ctatctgcgt
    34201 ctcctctacg cacgtgtggg gacgccttac tgtatcaacg gacatggagc tatcaatgct
    34261 tcttctgtgg agcaaatcgt tgataaggtt ttggagttac ctgaacgcca gcgcttgcag
    34321 atcttggctc ctgtcatccg caagaaaaaa ggccaacata agaatgttat cgagaaggtt
    34381 cagaaagacg gatatgttcg tgtccgtgtg gatggggaag tctatgatgt gaccgaagtg
    34441 ccagagttgt ctaagagcaa gcaacacaat atcgatgtcg tggttgaccg tattgttatc
    34501 aaggagggca ttcgtagccg tctctttgat tccattgaag ctgcccttcg tatcgcagaa
    34561 ggttatgtga ttatcgacac catggacgat tcggagttgc tcttctctga gcattatgcc
    34621 tgtccagttt gtggatttac tgtcccagag ttagagcctc gtctcttctc tttcaatgct
    34681 ccctttggct cttgtagtga gtgtgacggc ttggggatta agctggaggt ggatactgat
    34741 ttggtagtgc cagatgccag caaaacgcta cgtgaggggg ctttggcacc ttggaatcct
    34801 atctcatcta actactatcc aaatatgcta gagcaggcta tgacagcctt tggagtggat
    34861 atggataagc cctttgagga cttgtcagaa gaagataaga acttgattct ctacggctcg
    34921 gatggcaaag aatttcattt tcactatgag aatgaatttg gcggtgtgcg cgatattgac
    34981 attccttttg agggagtcgt cactaatatc aagcgtcgtt accatgagac taacagtgat
    35041 tacacgcgca ctcagatgcg tctctacatg aatgagctga cctgcggaac ctgtcaaggc
    35101 tatcgtctca atgaccaggc cttgtctgtc cgtgtgggcg gccagcaagg gccacatatt
    35161 ggagaaatct cagacctgtc tatcgctgac cacttggact tggtgagcca gttaactttg
    35221 tctgaaaatg aagccatcat tgctcgtccc attctcaagg aaatcaagga tcgtttgacc
    35281 ttccttaata atgtgggtct taactatcta accctgtcac gttcagcagg aaccctttca
    35341 ggtggggaaa gtcagcgcat tcgtttggca acccagattg gttccaacct atcaggtgtc
    35401 ctctatatcc tagacgagcc gtcaatcggt cttcaccaga gggacaatga tcgcctgatt
    35461 gccagtctga aaaagatgcg tgacttgggc aatactctta tcgtggtgga acacgacgaa
    35521 gataccatgc gtgaggctga ttatctgatt gacgttggtc ctggtgccgg tgtttttggt
    35581 ggtgagattg ttgcagcagg tacacctaag caagtggctc gcaacagcaa gtctatcaca
    35641 ggtcagtact tgtcaggcaa acgtgtcatc ccagtaccag aagagcgccg tgtcggaaat
    35701 ggtcgtttta ttgaagtgat aggagcgcgt gagaacaact tgcaaaatgt cacggctcgc
    35761 tttccactag gaaaatttat cgcagtgaca ggtgtgtcgg gttcagggaa atcgactcta
    35821 atcaacagca ttctcaaaaa agccattgcc cagaagctca accgtaattc agacaaacct
    35881 ggtaagttta agactattac agggattgag catgtcgacc gtttgattga tattgaccag
    35941 agccctatcg gacggacgcc gaggtctaac ccagctacct atacaggagt ttttgacgat
    36001 atacgtgacc tttttgctca gacaaatgaa gccaagattc gaggctacaa gaaggggcgc
    36061 ttcagtttca acgtcaaggg aggtcgctgt gaagcttgct caggtgacgg gattatcaag
    36121 attgagatgc acttcttgcc agatgtttat gtggcttgtg aagtttgcca cggaacccgc
    36181 tataacagtg aaaccctaga agttcactac aaggaaaaga atatttcgca ggtcttggat
    36241 atgacggtca acgatgcggt agaatttttc caacacattc cgaaaattca acgcaaactc
    36301 cagaccatca aggatgtagg gctaggctat gtgaccttgg gacagccagc taccactctt
    36361 tctgggggag aagcccaacg tatgaagtta gctagcgaac tccacaaacg ctcgacagga
    36421 aaatctttct acattctgga tgagccgacg acagggcttc atacagagga cattgctcgc
    36481 ctgctcaagg ttttagctcg ctttgtagac gatggcaata cagtcctcgt catcgagcac
    36541 aatctggatg ttatcaagac ggcagaccat atcattgact tgggacctga gggcggtgtc
    36601 ggtggtggaa ccatcatcgt aacaggaact ccagaagaag tagctgccaa cgaagccagc
    36661 tatacaggac actatttgaa aggaaagtta catcatgaat aaacgcgtac aagcatttct
    36721 agctaaaatg caagaaaaag aactagatgg tatcatcatc aacaatctta aaaacgtcta
    36781 ttatttgact ggtttttggg gctcaaacgg aacagtcttt atcagccgtg accgtcaggt
    36841 cttagtgaca gactctcgct atatcatcgc agctaagcaa gaaaccagtg gttttgagat
    36901 tgtggctgat cgtgatgaat tggctgtcat tgcaggaatt gttaaggaca tgggcttgac
    36961 tcgtatcggt tttgaagatg agatttcagt gtcttattac caccgtatgc aggcagcttt
    37021 tgcaggtttg aacttgcttc cacaaactca gtttgtggaa ggtcttcgta tgattaagga
    37081 tgaggcagag attgcagcga ttcgcaaggc ttgttctatc tcagaccaag ctttccgcga
    37141 tgcgcttgac tttatcaaac caggaaaaac tgaaattgag attgccaact tccttgattt
    37201 ccgcatgcgt gagttgggag catctggctt atcttttgat acgatcctag ctagcggtat
    37261 caattcttct aaaccccatg cccatccaat gcacaaacca gtggagttgg gagaagccat
    37321 taccatggac ttcggctgtc tctatgacca ctatgtcagt gatatgaccc ggactatcta
    37381 tctagggcat gttagcgatg agcaggcaga gatttacaat acggttctaa aagctaacca
    37441 agccttgatt gaccaagcta aggcaggctt aggtttccgt gactttgaca aaatccctcg
    37501 tgatattatc attgaggcag gttatggtga ctactttact cacggcattg gccacggtat
    37561 tggtctggat atccatgagg aaccctactt tagtcagact tctacagaaa ctattaagac
    37621 aggtatggcc ttgaccgatg aaccaggtat ctatatcgaa ggcaaatatg gcgttcgtat
    37681 cgaggatgat atcctgatta cagagacagg ttgtgaatta ttgaccctag ctccaaaaga
    37741 gttgatagtc atttagttgt ttgtcaagaa aaaagtacga aaatgacgaa aaaagtcaaa
    37801 aaaaattaaa aataggtcgc aagtcggatg ttttttatgg tataatagac taaactgata
    37861 gtaacatgta gcgaaagggg taggtacatg attaaaattt atacagtctc aagttgtact
    37921 agctgtaaaa aagcaaaaac ctggctcaat gcccaccagt taagttataa agaacaaaac
    37981 cttggtaaag aaggaattac gagagaagaa ttactggata ttctaaccaa aacagataac
    38041 ggaatagcca gcatcgtttc gtctaaaaat cgctatgcca aagcccttgg agtggatatt
    38101 gaagatttga gtgtcaatga agttctcaat ctgattatgg aaacaccgag aattttaaag
    38161 agcccaatcc ttgtagatga aaaacgcctg caagttggct acaaggaaga cgatattcgt
    38221 gccttcctac cacgctctgt ccgtaatgta gaaaatgcag aagcacgttt gcgtgcagct
    38281 ctataaacat caaggctggg agcacttccc agtcttattc tattttaatt tcaaaaagaa
    38341 agaagaaaga aatgaaaaaa atagttcttg ttagtctagc tttccttttt gtcctggttg
    38401 gttgcggaca gaaaaaagaa actggaccag ctacaaaaac agaaaaagat acgcttcagt
    38461 cggcattgcc agttattgaa aatgctgaga agaatacagt tgtaaccaag actttggtct
    38521 tgcccaagtc agatgatggt agccagcaga cacaaacaat tacttacaaa gacaagactt
    38581 ttttgagtct aactatccaa caaaaacgtc cagtctctga tgagttgaag acttatattg
    38641 accaacatgg agtggaggaa actcaaaaag ctcttcttga agcggaggag aaggataagt
    38701 ctatcattga agctcgtaaa ttggcaggtt tcaaacttga aacaaaacta ttgagcgcaa
    38761 cggaacttca aacaacgact agttttgatt ttcaagttct ggatgtcaag aaggcttccc
    38821 agttggaaca tctgaagaat attggtttgg aaaatctttt gaaaaatgaa ccaagcaaat
    38881 atatttcaga tagattggca aatggcgcga cagaacaata gaaaatccaa ataaatagac
    38941 tgcctgaatt gtagaaggta aggaattatg ctataatggt actattctaa ggaaagaggg
    39001 tgttagaatg ggatttactg aagaaacagt acgttttaaa ttggacgatt ccaataaaaa
    39061 agaaattagc gaaactttga cagatgttta tgcttcgttg aacgataagg gttacaaccc
    39121 aattaaccaa atcgtaggtt acgtattgag tggagaccct gcctacgttc ctcgttataa
    39181 taatgcacga aatcaaatcc gtaagtatga gcgtgatgaa atcgttgagg aattggttcg
    39241 ctactacctc aaaggacaag gagtcgatct ataacctatg agaattatgg gattggacgt
    39301 cggttcaaaa acggtagggg tggcgattag cgatccgctt ggttttacag ctcaagggct
    39361 tgaaatcatc cagataaatg aagaacaagg ccaatttggt tttgaccgcg ttaaggaatt
    39421 ggttgatact tacaaggtgg aacgatttgt agtgggcttg cctaaaaaca tgaacaatac
    39481 aagtggaccg cgcgtagaag ctagtcaagc ctacggagca aagctagaag agttttttgg
    39541 tttaccagta gactatcagg atgaacgctt gacaacagtg gctgctgagc gcatgttgat
    39601 tgaacaagca gatatcagtc gcaataagcg caagaaagtc attgataagt tagcagctca
    39661 gctgatttta caaaattatt tagatagaaa attttaatat aaaggagagg ctatgtcaca
    39721 cgatcataac cacgaccacg aagaacgtga actaatcaca ctagtagatg agcaaggaaa
    39781 tgaaaccttg tttgaaatcc ttttgacaat tgatggaaaa gaagaatttg gtaaaaacta
    39841 tgttcttcta gtaccagtta acgcagaaga agacgaagac ggacaagttg aaatccaagc
    39901 ttactcattc atcgaaaacg aagatggaac agaaggcgaa ttgcaaccaa tcccagaaga
    39961 ctcagaagac gaatggaaca tgattgaaga agtcttcaat agttttatgg aggagtaaaa
    40021 atgttcagtg aatattttta ccccagttcc tttaaataag agagaactgg taagtccggg
    40081 ggacgttttt agcccagctc cttgaagtaa gagagagctg gtaagtccgg ggacgttttt
    40141 agccctgctt ttagaaaaaa gaaagagcag gcagtctggg agactgtatc agcccaactc
    40201 ccagaaatgg ggaagagttg gaacatccag tggatgtttt tagcccagtt cctttaaata
    40261 agagagaact ggtaagtccg ggggacgttt ttagcctgac gctaaaaata aaaacagtca
    40321 gtaagttcgg gggatgtttt agcccagctc cttgaaataa gatagagctg gtaagtctga
    40381 gaaactgtat cagcccaact cccagaaatg gggaagagtt ggaacgtcca gtgaacattt
    40441 ttaccccaac tcttagaaat tgagaagagt tggaacatct agtggatgtt tttagcccat
    40501 attcacattc atagtagcta gttattagct aaccaggtaa gaggtcggga cgaaaatcct
    40561 ggccttgttt ttattagtaa ccatacttta atgcgataat tgattggact tttgtcaagg
    40621 agatgtgtat gtttgaagta gaagaatggc tccatagtcg gattggtttg aattttcgat
    40681 caggtttggg ccgaatacag caagcggtgg atttgttagg aaatcctgag cagtcttacc
    40741 ctattatcca cgtaacaggg actaatggaa aaggatctac cattgctttt atgagggaat
    40801 tatttatggg gcatggcaaa aaagttgcga cctttacctc ccctcatatc gtctctatca
    40861 atgaccgaat ctgcattaat gggcaaccta tagcagacgc agactttatc cgtttggctg
    40921 atcaggtcaa ggagatggag aaaacgcttc tgcaaactcc tgaccagttg tccttttttg
    40981 aattgctgac cttagttgct tttctttatt ttagggagca agaggtggat ttggttttat
    41041 tagaagtggg aattggtggc ttacttgaca cgaccaatgt ggtaactgga gagcttgctg
    41101 tcatcacctc cattgggctt gaccatcaag aaaccttggg tgatagtcta gaagcaattg
    41161 cagagcagaa agctggtatt ttcaaggctg gtaagaaggc agtgattgcg aaattgcctc
    41221 cagaagctag gcttgtctgt cagaaaaaag ccgaatcttt agctgttaac ctttatcagg
    41281 caggtcaaga ttttttaatg ctgaatggtg atttttcaag ctctttacta aatctttcac
    41341 agctgaacat aggcttagaa ggagtctatc agcaggagaa tgcagccttg gcgttgcaaa
    41401 cttttcttct ttttatggga gaaggaaagg aagctgttga tgaacaggct gtaagaaagg
    41461 ccttggaaca gacccattgg gctggtcgct tggagcgtat tcgcccacag atttacttgg
    41521 atggtgctca taacctccct gccttgactc gcttggttga gtttatcaaa gaaaaagagc
    41581 aggaaggtta tcgacctcaa atcctctttg gatccttgaa acgtaaggat tatcaaggga
    41641 tgttgggtta tctgactgaa aatttacctc aagtggaact caaaatgact ggctttgact
    41701 atcaagggtc tttggacgag acagatgtaa caggttacca tgtaattccc tcttaccgag
    41761 aatttatcag cattttcgaa gaaagggcag acgctcaaga cttgctgttc gttacagggt
    41821 ctctctattt tatctcagaa gtacggggct acctgctgga ccgtgagcag ataaattgac
    41881 ccccttgttt gaacttgtta tactagggga attgctggtt agagaaaatt tctctaaatt
    41941 ggtagcagaa aggaaattca tcatgaaatt aaaaagattc acactttctc ttgcttctct
    42001 agcaagtttt agtctcttag tagcttgttc acaaagagct caacaggttc aacagcctgc
    42061 tcaacaacct gctcaacaga ataccaatac tgcaaatgca ggaggtaacc aaaatcaagc
    42121 ggctccagta caaaaccaac ctgttgctca accgaccgat attgatggga cttatactgg
    42181 tcaggatgac ggagaccgta tcactttagt ggtaactgga acgactggta catggactga
    42241 gctcgaatct gacggggatc agaaagtcaa acaggttaca tttgattcag caaatcaacg
    42301 catgattatt ggcgatgatg tcaaaattta cactgtaaac ggtaatcaaa tcgtcgtaga
    42361 tgatatggat agagacccat cggaccaaat cgttttaact aaataagact atgcaagtag
    42421 aaagggctgg atttttcagc ctttttactt ttacctagaa aataatcata aatacttgcc
    42481 ttctaccgaa tacctgcgtt atactagtat caattacttg tttttagcat tcaaactatc
    42541 aaggagggga tatgaaatat aggaaatttc aattattgat gtccaagtat ggctttagtc
    42601 tttcgattat gctacttgaa ctttgtcttg tttttggtct ctttctttat ttaggacgca
    42661 tggctcccat tttatggatt actgtcctca ttctactgag tatcatcaca atcatttcga
    42721 tagtcaaccg taatacgact cctgagaata aggtaacctg gttgttagta gcctttgtgc
    42781 cagtatttgg tcccttgctc tatctgatgt ttggtgaaag gcgattgtcc aaaaaagaaa
    42841 tcaaacaact gaagaagcta ggctctatgc atttccaaga agcaaatagc cagctactaa
    42901 aagagaaatt aaaagaaagt gacaaggcag cttatggagt catcaagtcc ttattgagta
    42961 tggataccaa tgctgacatc tatgatcaaa ctgcctctac attttttcct aacggagaag
    43021 ctatgtggaa aaagatggta gaagatctta aaaaggctga gaaatttatt ttcttggaat
    43081 attacattat agaagaaggt ttgatgtgga atcgcatact agatatacta gagcaaaagg
    43141 tagctcaggg tgtagaggtt aagatgctct atgatgatat cggctgtatg gctactttaa
    43201 caggagatta tgcacatcga cttcgtcagc tgggcatcga ggcccataaa ttcaataaag
    43261 ttattcctcg tctgacagtg gcttataata acagagatca tagaaaaata ttgattgttg
    43321 atggtcagat agcctatact ggtggggtca atctggcaga tgagtacatt aaccacgtcg
    43381 agagatttgg ttattggaag gatagtggaa ttcgcttaga cggactagca gtaaaagccc
    43441 tgacacgctt atttttgacc acttggtaca ttaatcgagg agaaattagt gattttgatc
    43501 aatatcattt agaaaatcat tctatcccga gtgacggttt aaccattcca tacggaagtg
    43561 gacccaagcc aatttttcga gcgcaggtag ggaaaaaagt ttatcagagt ttaatcaatc
    43621 aagcaacaga atcggtctat attacgacac cttatttgat tatagattat gatttaacag
    43681 agacaatcaa aaatgcagct atgagagggg tcgatgttcg aattatcacc ccttacatac
    43741 cagataagaa gttcattcag ttagtcacga gaggagctta tcccgacctt ctttctgctg
    43801 gtgttcggat ttatgagtat agtccaggtt ttattcatag taagcagatg ttggtagacg
    43861 aagattttgc ggtggtgggg acaatcaatc tcgactaccg gagcttggta caccattatg
    43921 aaaatgcagt cttactctat aaaactcctt ctataaggga aatcgcccga gattttcgaa
    43981 atatatttgc agattctcag gaagtctatc ctcattctat caaaacgagc tggtatcaaa
    44041 agcttgtaaa agaaatcgcc cagctattcg cccctatctt ataagaaatc tagaacttag
    44101 gatacaaacc agacctattt ttcttgtctt ttacgaatag aaagaaagag gaggggaatt
    44161 catgctaact aaggaagaag tgaatgatat gattgagttc aaacagacac atttacaccg
    44221 ctttcgggaa attgaaacct ttgtgaaact atgcaaaaaa tcactcaaac agccatcgca
    44281 agctgacaat cctaggactt tttgatatac taagacagat aaattgaaca ggagaaacga
    44341 tatgagtgtg tatggtagag tagaagaagt tcataaggag aatcgtgaac ctctagaata
    44401 ccaaatcgaa caagaatcgc ataatcgtga atcaagtcgt cttcctttgg tgaaaatttt
    44461 actatggagt acgcttgtaa cggggataac tctaggagta ccgctattac tcgacttaat
    44521 gagtgcacaa gaagtgcagg atttttatgc aggttgggcg cttcatcaga cagggaagat
    44581 ttacagcgac tattatggaa gtcaaggttt gctttattat ttgctgactt acgtgagtca
    44641 gggcggattt ttctttgcca tctttgagtg gttagccttg gtagcaggag gatttttcct
    44701 ttttagatca gcggacacct tgacagagca aggagaccaa gctggacatc tggtgactat
    44761 tttttacatg ctagttacag gtcttgcttt tggtggaggc tatgcgactc ttttagcgct
    44821 tcctttctta ttcgcagcct ttagtttagt tgcggcttac ctaagcaatc caagccatga
    44881 taagggattt gtacggattg ggctagcttt ggcaggcgga tttttctttg ctcccttatc
    44941 atcgctcctg tttattgctg tagtgagttt aggcttgttg gtctttaacc ttgggcatag
    45001 acgctttgcg catgggtttt atcagtttct tgcagtggct ttaggttttt cacttgtctt
    45061 ttatccaact gcctactata gtgctgcaac aggaagtttt ggggatgcga ttagtggtat
    45121 tcgttatcct attgacagta ttcgctttga ttttacttct aaaattttag agaatatgtt
    45181 tttttatggc ttgttgtccc ttggtttggg atttgtggtt tgtatctttt taggtctctt
    45241 tcaatccaaa ccctttaaac tatacgtcat ttcggttcct gcaagtcttg tggtaatttt
    45301 aggtttgatt ttacttttct tttcacaaga gcctctgcac gcttcttatt tgatggtcgt
    45361 cttccctgtt ttcctacttt tattggtaac caatattaag agtcaacaga gggggcgtag
    45421 tgctagaaga agcctaagag aaacgccagt tagcctatgg agtcgtttct tcaaaggaaa
    45481 tctatatctg ctagtttttg ggtttgtcta tcttttgtct gttccttttt tgatgaagtt
    45541 tgtcctttat ccagtacctt atcaagaacg taatcgtctt gctgatttgg taaaagagga
    45601 gacaaatacg gaagatgcta tctatgcatg ggatgatact gcgactcttt atcgtaagag
    45661 tgagcgcttg tcgccatcgg cgattttgtc cccgttgcac tatacagcaa ctgaggaaaa
    45721 tcgtaataag ttacttaatg acttgaaaga aaaacaacct aaggtgattg tggtaaatga
    45781 caaggtggta gtctggtctg aagtggaaac acttttaaaa gaaaattacc aacaagtaaa
    45841 gactgattac tcagagttta aagtctataa aattaaataa ccaaatcaat atcttgtgta
    45901 tttttaaaaa ttttaggatt tttaacacaa gatattgatt tttcttttta gagtggtata
    45961 atacttttta gaaagaacat tttagaaaag agcatgcgta tgattgcact agaagaaaaa
    46021 attacaattt tgccaactct cttcgtcgag aaacgagatg ggagacgtgt tgtatttgat
    46081 gtggacaaga ttgacaaggc tctccacaag gcggctgaca aggttatgga tgtgacaccc
    46141 ctggttgaaa aacgcctcaa tgatctgact gagcgaatta ttacagaaat tcatagtcgc
    46201 tttccacagg gaattaagat ttacgaaatt caaaatatcg tagaacatga actccttgaa
    46261 gccaaagaat atgcgctggc tgaggagtat attacttatc ggacacagag ggattttgag
    46321 cgctcaaaag cgacggatat caactttagt attcataaac ttctcaacaa agaccagaca
    46381 gttgtcaatg aaaatgctaa taaagacagt gatgtcttta acactcagcg tgatttgaca
    46441 gcagggattg ttgggaaatc aatcggactg caaatgcttc ctaagcacgt agccaatgcc
    46501 caccaaaagg gggatatcca ctatcacgat ttggactaca gtccctatac ccctatgacc
    46561 aactgctgtt tgattgattt taagggtatg ttggaaaatg gttttaagat tggaaatgca
    46621 gaggtagaga gtcccaagtc tatccagact gcgacagcac agatttctca aatcattgcc
    46681 aacgttgctt ctagccagta cggtggctgt tcagctgacc gtatcgatga aattttggcg
    46741 ccttatgcag agaagaacta tcaaaaacat ctcaaagatg cagaagagtg ggtattgcct
    46801 gaaaaacggg aagattacgc ttggaagaaa acgcaaaagg acatctacga tgccatgcaa
    46861 tctcttgagt atgaaatcaa tactctcttc acttcaaatg gacaaacacc ttttacttcg
    46921 ttaggttttg gtctgggaac cagtcgtttt gaacgagaaa ttcaaaaagc tattttaaac
    46981 attcgcatca agggtcttgg ttcagaacac cgtacggcta tctttcctaa acttatcttt
    47041 acgcttaaaa gaggcctcaa cttagaggaa ggaactccca actatgacat caagcagttg
    47101 gctctagagt gtgcaaccaa gcggatgtat ccagacgtct tgtcttatga taagattgtt
    47161 gatttgacag gttctttcaa agttcctatg ggctgccgtt ctttccttca agggtggaag
    47221 gatgaaaatg gtgtagaagt caattcaggt cgcatgaatc tgggtgttgt gacggttaat
    47281 ctgcctcgta ttgctcttga gtctgaaggt gatatgaata agttctggga aatcttcaac
    47341 gagcgaatga atatcgcaga agatgctctt gtttaccgtg tcgaacgcac taaagaggcg
    47401 acaccagcga atgctcctat tctttatcag tacggtgctt ttggccatcg tctaggtaaa
    47461 gaagaaagtg ttgaccagct ctttaagaat cgtcgtgcga ccgtttcgct gggctatatc
    47521 ggcttgtatg aagtagcgac agttttcttt ggtaacagct gggaaagtaa tccagatgct
    47581 aaggaattca cgctagacat cattcacgat atgaaacgcc gtgtagaaga gtggtcagac
    47641 caatatggct accatttctc tatctactca acaccatccg aaagtctgac agaccgtttc
    47701 tgccgactag atatagacaa gtttggctct attcctgata tcacagacaa ggaatactac
    47761 accaactctt tccactacga tgttcgtaaa aatccaacac cgtttgaaaa attggacttt
    47821 gagaaagtct atccagaagc aggtgcgtca ggtggtttca tccattattg tgagtatcca
    47881 gtccttcagc aaaatccaaa ggccttggaa gctgtctggg attatgctta tgaccgtgta
    47941 ggctatctag gcaccaatac tccgattgac cgttgctaca agtgtgactt tgaaggggat
    48001 tttgaaccaa ctgagagagg gtttgcttgt ccaaactgtg gcaatagcga tcctaaaaca
    48061 gtagacgttg ttaaacggac ttgtggctat cttggcaatc ctcaagcgag accaatggtt
    48121 aacgggcgtc acaaggaaat cgctgcgcgt gtcaaacata tgaatggttc aacgattaaa
    48181 atagctgggc atcaagtaac aaattagaaa gaaatgaaat gggaaaatat caactagacg
    48241 ataaggggcg cgcacaagtg acccgttatc acgagaagca ctctaaaggt ggagctggta
    48301 agaaagaacg cttgcttagc ttcagagaac aatttttaaa caagaacaag aaaaaataaa
    48361 agtgagagcc agctctcgct tttctcatag tgggaggtag ggatggaatt acgcagacca
    48421 agattagcgg ataagaaagc tgttttagat atgatgacag agtttgaaaa gagccaatca
    48481 gcccatgatg gaggattttg ggatacagag aattttgtgt atgaagagtg gttggaaagc
    48541 aatcaggaac aggaaatggg gattaatctg cctgaaggat gggttcctgc aattcagtta
    48601 gtggcttttt ctgagaaagg tcaagcagtt ggatttctta atctccggtt gcgcctcagt
    48661 aactttttac tagaagaagg tgggcacatt ggctactcca tccgtccatc tgaaagaggc
    48721 aagggttatg caaaagagac tctccgtcag ggcttgcaag ttgctaagga aaagaacatc
    48781 aagaaagctc tggtgacctg tagcgtgaat aatcctgcta gcagagcagt cattctagca
    48841 aatggtggaa tatttgagga tgctcacaat ggagtcgagc gttattggat agaggtagcg
    48901 aatgaataat ccaaaaccac aagaatggaa aagcgaggaa cttagtcaag gtcgtatcat
    48961 tgactacaag gcctttaact ttgtggacgg cgaaggcgtg cgtaactctc tctatgtatc
    49021 aggctgtatg tttcactgcg agggatgtta taatgttgcg acttggtctt ttaatgctgg
    49081 cattccctat acagcagaat tagaagagca gatcatggca gatcttgctc agccctatgt
    49141 tcaaggtttg actttgttgg gaggggagcc ttttcttaat actgggattc tcttgccact
    49201 tgttaagcgg attcggaagg aattgccaga caaggacatc tggtcctgga ccggctacac
    49261 ttgggaagaa atgatgttgg aaactccaga taaactggaa ttcttgtcac tgattgacat
    49321 tcttgtcgat ggaagatatg atcgaactaa gagaaatctt atgctccagt ttcgaggttc
    49381 atctaaccaa cgaattatcg atgtgcaaaa atcgctcaaa agtgggcaag tagtgatttg
    49441 ggacaagctc aatgacggaa aagaaagcta tgaacaggtg aagagagaat gaagaaaaaa
    49501 gacttagtag accaactagt ctcagagatc gagacgggga aagtcaggac actgggaata
    49561 tacggtcatg gagcttcagg taaatcaacc tttgcacagg aattgtacca agctttagat
    49621 tctactacag taaatttgct agaaacagat ccctatatca cctccggacg ctatttggta
    49681 gtacccaagg acgcgccgaa tcaaaaggtg acagccagtc tgccagtggc gcatgaactg
    49741 gagagtttgc agagagatat ccttgccttg caggcgggta tggatgtctt gacaattgaa
    49801 gaaccttgga aggctagtga ggtcttgtct ggagccaaac caattttgat tgtcgaaggg
    49861 atgtctgttg gttttctacc caaggaactc tttgaaaaaa ccatctgttt ctacacggat
    49921 gaggagaccg aattaaagcg acgccttgct agagatacga ctgtgagaaa tcgcgatgca
    49981 tcctttatat tggctagcca tcagatgaga cgggagcagt atctgcgata ctataaagaa
    50041 actgagtcta aggcggatat cttagtggac caatcagaag ataaatttga tgtcaagagg
    50101 acttaactta tgtatagaag aaatatagaa gaaaatccct aattttagaa agaaaaagta
    50161 ggaaaacagt ttcatcccaa aaaaacgaaa aaacctaaca aatcccttgc aatcgcaggg
    50221 gatttgtgtt attctattat ggtgctgtaa attacagcct tagttttgat gcaagaggtt
    50281 gcgacacgct cggttgcatt gccacgcaac accgcgtcgg ttttcttgtg gagctagcct
    50341 attatcttaa atagacgaaa aggagaaaaa gatggcaaac aaaaaaatcc gtatccgttt
    50401 gaaagcttac gaacaccgta cgcttgacac agcggctgca aaaatcgtag aatcagctac
    50461 tcgtacaggt gcacaagttg cgggtccaat cccacttcca actgaacgta gcctctacac
    50521 aatcattcgt gcgactcaca aatacaaaga ctctcgcgaa caatttgaaa tgcgtacaca
    50581 caaacgtttg atcgatatcg ttaacccaac tcaaaaaaca gttgatgcct tgatgaaatt
    50641 ggatcttcca agtggtgtaa acgtagaaat caaactttaa tctaaaatat aaaagagcag
    50701 aggctggtgt ttcaatctaa ttgaacacgg gctaaactcg gtgtgaaaaa gataaacttc
    50761 ctcgcgtctg ctagacactg tgtcagtttc ctattttcac gttgagtttg acgccctttg
    50821 tatcttagac ttgagcataa aaaacgctcg ttaaaaactt tttgaataaa aaatatagaa
    50881 aaggaactat tttctcatga caaaaggaat cttagggaaa aaagtgggaa tgactcaaat
    50941 cttcactgaa gctggcgaat tgatccctgt aacagttatt gaagcaactc caaacgttgt
    51001 tcttcaagtt aaaactgttg aaacagacgg atacaacgct atccaagttg gtttcgatga
    51061 caaacgcgaa gtattgagca acaaacctgc taaaggacat gtagcgaaag ctaacacggc
    51121 tcctaagcgc ttcattcgtg aattcaaaaa cgttgaaggc ttggaagttg gtgctgaaat
    51181 tacagttgaa acattcgcag ctggagacgt tgttgacgta actggtactt ctaaaggtaa
    51241 aggtttccaa ggtgttatca aacgccacgg acaatcacgt ggaccaatgg ctcacggttc
    51301 tcgttaccac cgtcgtccag gttctatggg acctgttgca cctaaccgcg tattcaaagg
    51361 taaaaacctt gcaggacgta tgggtggtga ccgcgtaaca attcaaaatc ttgaagttgt
    51421 acaagttgtt ccagaaaaga acgttatcct tatcaaaggt aacgtaccag gtgctaagaa
    51481 atctcttatc actatcaaat cagcagttaa agctggtaaa taataaagaa aggggaaatc
    51541 agtcacaatg gcaaacgtaa cattatttga ccaaactggt aaagaagctg gccaagttgt
    51601 tcttagcgat gcagtatttg gtatcgaacc aaatgaatca gttgtgtttg atgtaatcat
    51661 cagccaacgc gcaagccttc gtcaaggaac acacgctgtt aaaaaccgct ctgcagtatc
    51721 aggtggtgga cgcaaaccat ggcgtcaaaa aggaactgga cgtgctcgtc aaggttctat
    51781 ccgctcacca caatggcgtg gtggtggtgt tgtcttcgga ccaactccac gttcatacgg
    51841 ctacaaactt ccacaaaaag ttcgtcgcct agctcttaaa tcagtttact ctgaaaaagt
    51901 tgctgaaaac aaattcgtag ctgtagacgc tctttcattt acagctccaa aaactgctga
    51961 atttgcaaaa gttcttgcag cattgagcat cgattctaaa gttcttgtta tccttgaaga
    52021 aggaaatgaa ttcgcagctc tttcagctcg taaccttcca aacgtgaaag ttgcaactgc
    52081 tacaactgca agtgttcttg acatcgcaaa tagcgacaaa cttcttgtca cacaagcagc
    52141 tatctctaaa atcgaggagg ttcttgcata atgaatttgt atgatgttat caaaaaacct
    52201 gtcatcactg aaagctcaat ggctcaactt gaagcaggga aatatgtatt tgaagttgac
    52261 actcgtgcac acaaactttt gatcaagcaa gctgttgaag ctgctttcga aggtgttaaa
    52321 gttgccaatg ttaacacaat caacgtaaaa ccaaaagcta aacgtgttgg acgttacact
    52381 ggttttacta acaaaactaa aaaagctatc atcacactta cagctgattc taaagcaatc
    52441 gagttgtttg ctgctgaagc tgaataatct aaggaggaaa tatcgtggga attcgtgttt
    52501 ataaaccaac aacaaacggt cgccgtaata tgacttcttt ggatttcgct gaaatcacaa
    52561 caagcactcc tgaaaaatca ttgcttgttg cattgaagag caaggctggt cgtaacaaca
    52621 acggtcgtat cacagttcgt caccaaggtg gtggacacaa acgtttctac cgtttggttg
    52681 acttcaaacg taataaagac aacgttgaag cagttgttaa aacaatcgag tacgatccaa
    52741 accgttctgc aaacatcgct cttgtacact acactgacgg tgtgaaagca tacatcatcg
    52801 ctccaaaagg tcttgaagta ggtcaacgta tcgtttcagg tccagaagca gatatcaaag
    52861 tcggaaacgc tcttccactt gctaacatcc cagttggtac tttgattcac aacatcgagt
    52921 tgaaaccagg tcgtggtggt gaattggtac gtgctgctgg tgcatctgct caagtattgg
    52981 gttctgaagg taaatacgtt cttgttcgtc ttcaatcagg tgaagttcgt atgattcttg
    53041 gaacttgccg tgctacagtt ggtgttgtcg gaaacgaaca acatggactt gtaaaccttg
    53101 gtaaagcagg acgtagccgt tggaaaggta tccgcccaac agttcgtggt tctgtaatga
    53161 accctaacga tcacccacac ggtggtggtg aaggtaaggc accagttggt cgtaaagcac
    53221 catctactcc atggggcaaa cctgctcttg gtcttaaaac tcgtaacaag aaagcgaaat
    53281 ctgacaaact tatcgttcgt cgtcgcaacg agaaataata ttaaactagt cgcttaagca
    53341 actagtaaat ccgccagctc ggtagcgctc cataggagtg caagccgctg tggtacaaca
    53401 tttaaaggag aaaatataaa aatgggacgc agtcttaaaa aaggaccttt cgtcgatgag
    53461 catttgatga aaaaagttga agctcaagct aacgacgaaa agaaaaaagt tattaaaact
    53521 tggtcacgtc gatcaacgat cttcccaagt ttcattggtt acactattgc agtttatgac
    53581 ggacgtaaac acgtacctgt ttacatccaa gaagacatgg taggccacaa acttggtgaa
    53641 tttgcaccaa ctcgtactta caaaggtcac gctgcagacg acaagaaaac acgtagaaaa
    53701 taaggagaac ataaatggca gaaattactt cagctaaagc aatggctcgt acagtacgtg
    53761 tttcacctcg taaatcacgt cttgttcttg ataacatccg tggtaaaagc gtagccgatg
    53821 caatcgcaat cttgacattc actccaaaca aagctgctga aatcatcttg aaagttttga
    53881 actcagctgt agctaacgct gaaaacaact ttggtttgga taaagctaac ttggtagtat
    53941 ctgaagcatt cgcaaacgaa ggaccaacta tgaaacgttt ccgtccacgt gcgaaaggtt
    54001 cagcttcacc aatcaacaaa cgtacagctc acatcactgt agctgttgca gaaaaataag
    54061 gaggtaaaat cgtgggtcaa aaagtacatc caattggtat gcgtgtcggc atcatccgtg
    54121 attgggatgc caaatggtat gctgaaaaag aatacgcgga ttaccttcat gaagatcttg
    54181 caatccgtaa attcgttcaa aaagaacttg ctgacgcagc agtttcaact attgaaatcg
    54241 aacgcgcagt aaacaaagtt aacgtttcac ttcacactgc taaaccaggt atggttatcg
    54301 gtaaaggtgg tgctaacgtt gatgcactcc gtgcaaaact taacaaattg actggaaaac
    54361 aagtacacat caacatcatc gaaatcaaac aacctgattt ggatgctcac cttgtaggtg
    54421 aaggaattgc tcgtcaattg gagcaacgtg ttgctttccg tcgtgcacaa aaacaagcaa
    54481 tccaacgtgc aatgcgtgct ggagctaaag gaatcaaaac tcaagtatca ggtcgtttga
    54541 acggtgcaga tatcgcccgt gctgaaggat actctgaagg aactgttccg cttcacacac
    54601 ttcgtgcaga tatcgattac gcttgggaag aagcagatac tacatatggt aaacttggtg
    54661 ttaaagtatg gatctaccgt ggtgaagttc ttccagctcg taaaaacact aaaggaggta
    54721 aataaccaat gttagtacct aaacgtgtta aacaccgtcg tgaattccgt ggaaaaatgc
    54781 gcggtgaagc aaaaggtgga aaagaagtag cattcggtga atacggtctt caagctacaa
    54841 ctagccactg gatcactaac cgccaaatcg aagctgctcg tatcgccatg actcgttaca
    54901 tgaaacgtgg tggtaaagtt tggattaaaa tcttcccaca caaatcatac actgctaaag
    54961 ctatcggtgt gcgtatggga tctggtaaag gggcacctga aggttgggta gcaccagtta
    55021 aacgtggtaa agtgatgttc gaaatcgctg gtgtatctga agagattgca cgtgaagcgc
    55081 ttcgacttgc tagccacaaa ttgccagtta aatgtaaatt cgtaaaacgt gaagcagaat
    55141 aaggagaagg catgaaactt aatgaagtaa aagaatttgt taaagaactt cgtggtcttt
    55201 ctcaagaaga actcgcgaag cgcgaaaacg aattgaaaaa agaattgttt gaacttcgtt
    55261 tccaagctgc tactggtcaa ttggaacaaa cagctcgctt gaaagaagtt aaaaaacaaa
    55321 tcgctcgtat caaaacagtt caatctgaag cgaaataata gactagggaa ggagaaattt
    55381 caatggaacg caataatcgt aaagttcttg ttggacgtgt tgtatctgac aaaatggaca
    55441 agacaatcac agttgtagtt gaaacaaaac gtaaccaccc agtctatggt aaacgtatta
    55501 actactctaa aaaatacaaa gctcatgatg aaaacaatgt tgccaaagaa ggcgatatcg
    55561 tacgtatcat ggaaactcgc ccgctttcag ctacaaaacg tttccgtctt gtagaagttg
    55621 ttgaagaagc ggtcatcatc taatcaaacc tgaaaggaga aaactgaaat gattcaaaca
    55681 gaaactcgtt tgaaagtcgc agacaacagc ggtgctcgcg aaatcttgac tatcaaagtt
    55741 cttggtggtt caggacgtaa atttgcaaac atcggtgatg ttatcgtggc atctgtaaaa
    55801 caagctactc ctggtggtgc ggttaaaaaa ggtgacgttg ttaaagcagt tatcgttcgt
    55861 actaaatcag gtgctcgtcg tgctgatggt tcatacatca aatttgacga aaacgcagca
    55921 gttatcatcc gtgaagacaa aactcctcgc ggaacacgta tctttggccc agttgcacgt
    55981 gaattgcgtg aaggtggctt catgaagatc gtgtcacttg ctccagaagt actttaattt
    56041 ttaggaacaa actagtcccc tagcttcaag ctagggtgcc cttatgggcg taagaaaaat
    56101 caaggagaaa cctaatgttt gtaaaaaaag gcgacaaagt tcgcgtaatc gctggtaaag
    56161 ataagggaac agaagctgtt gtccttactg cccttccaaa agtaaacaaa gttatcgttg
    56221 aaggtgttaa cattgttaag aaacaccaac gtccaactaa cgagcttcct caaggtggta
    56281 tcatcgagaa agaagcagct atccacgtat caaacgttca agttttggac aaaaatggtg
    56341 tagctggtcg tgttggttac aaatttgtag acggtaaaaa agttcgctac aacaaaaaat
    56401 caggcgaagt gcttgattaa tcacgaagga aaggagaagt ataatggcaa atcgtttaaa
    56461 agaaaaatat cttaatgaag tagttcctgc tttgacagaa caattcaact actcatcagt
    56521 gatggctgtg cctaaagtag ataagattgt tttgaacatg ggtgttggtg aagctgtatc
    56581 aaacgctaaa agccttgaaa aagctgctga agaattggca cttatctcag gtcaaaaacc
    56641 acttatcact aaagctaaaa aatcaatcgc cggcttccgt cttcgtgaag gtgttgcgat
    56701 cggtgcaaaa gttacccttc gtggtgaacg tatgtacgaa ttcttggata aattggtatc
    56761 agtttcactt ccacgtgtac gtgactttca cggtgttcca acaaaatcat ttgatggacg
    56821 cgggaactac acacttggtg tgaaagaaca attaatcttc ccagaaatca acttcgatga
    56881 cgttgacaaa actcgtggtc ttgacatcgt tatcgtaaca actgctaaca ctgacgaaga
    56941 gtcacgtgca ttgcttacag gccttggaat gccttttgca aaataatata ggaggtaaat
    57001 ctaatggcta aaaaatcaat ggtagctaga gaggctaaac gccaaaaaat tgttgaccgt
    57061 tatgctgaaa aacgtgctgc attaaaggcg gcaggggact acgaaggttt atctaaatta
    57121 cctcgcaacg cctcaccgac tcgtttacat aatcgttgta gagttacggg gcgcccacat
    57181 tcagtttacc gcaaatttgg tctgagtcgt atcgcttttc gcgaacttgc gcataaaggt
    57241 caaattcctg gtgtaacaaa agcatcttgg taatttaaga tatcaagggt gtcaaaactc
    57301 caagtaaaaa taggaaactt gacgaagaaa ctaaagtttc taggaaagtt tatctttttc
    57361 acacagagtt tagcccgggt tcaattgggc ttgccaattt gaacccgagc tacagctttg
    57421 gcaaaaaaga ccaatttgct ttggagcatt gcttctgcat taaattgtct atttttgctc
    57481 gtgctgttac gctctttgta tcatgtatta actagcaagt gcaacttgca aactactagt
    57541 aagaggagaa aaacaaaatg gttatgactg acccaatcgc agacttccta actcgtattc
    57601 gtaatgctaa ccaagctaaa cacgaagtac ttgaagtacc tgcatcaaac atcaaaaaag
    57661 ggattgctga aatccttaaa cgcgaaggtt ttgtaaaaaa cgttgaaatc atcgaagatg
    57721 acaaacaagg cgtcatccgt gtatttctta aatacggacc aaatggtgaa aaagttatca
    57781 ctaacttgaa acgtgtttct aaaccaggac ttcgtgtcta caaaaaacgt gaagaccttc
    57841 caaaagttct taacggactt ggaattgcca tcctttcaac ttctgaaggt ttgcttactg
    57901 ataaagaagc acgccaaaag aatgttggtg gtgaggttat cgcttacgtt tggtaaaatc
    57961 aagatacaaa gctcgtaaag aacaaagcaa aattaggaag ttggagaagt ttgtttacaa
    58021 acaagccaac ttatctattt tgcacagttc ttagagcgtg ttcagttcag ctcttgaact
    58081 aaataagtat ctgaaccccg tgaaaactgg ccgttctggc ctgacaattt aacaggagaa
    58141 aataaacatg tcacgtattg gtaataaagt tatcgtgttg cctgctggtg ttgaactcgc
    58201 taacaatgac aacgttgtaa ctgtaaaagg acctaaagga gaacttactc gtgagttctc
    58261 aaaagatatt gaaatccgtg tggaaggtac tgaaataact cttcaccgtc caaacgattc
    58321 aaaagaaatg aaaactatcc acggaactac tcgtgccctt ttgaacaaca tggttgttgg
    58381 tgtatcagaa ggattcaaga aagaacttga aatgcgtggg gttggttacc gtgcacagct
    58441 tcaaggatct aaacttgttt tggctgttgg taaatctcat ccagacgaag ttgaagctcc
    58501 agaaggaatt acttttgaac ttccaaaccc aacaacaatc gttgttagcg gaatttcaaa
    58561 agaagtagtt ggtcaaacag ctgcttacgt acgtagcctt cgttcaccag aaccatataa
    58621 aggtaaaggt atccgttacg ttggtgaatt cgttcgccgt aaagaaggta aaacaggtaa
    58681 ataatgttga gtggttgatc atcaaccacc aacctatttt ccaactttgt gcatagcaca
    58741 cgatttaaaa ctaaagaggt gaaaactgtg atttcaaaac cagataaaaa caaactccgc
    58801 caaaaacgcc accgtcgcgt tcgcggaaaa ctctctggaa ctgctgatcg cccacgtttg
    58861 aacgtattcc gttctaatac aggcatctac gctcaagtga ttgatgacgt agcgggtgta
    58921 acgctcgcaa gtgcttcaac tcttgataaa gaagtttcaa aaggaactaa aactgaacaa
    58981 gccgttgctg tcggtaaact cgttgcagaa cgtgcaaacg ctaaaggtat ttcagaagtg
    59041 gtgttcgacc gcggtggata tctatatcac ggacgtgtga aagctttggc tgatgcagct
    59101 cgtgaaaacg gattgaaatt ctaataggag gacactagaa aatggcattt aaagacaatg
    59161 cagttgaatt agaagaacgc gtagttgctg tcaaccgtgt tacaaaagtt gttaaaggtg
    59221 gacgtcgtct tcgtttcgca gctcttgttg ttgttggtga ccacaatggt cgcgtaggat
    59281 ttggtactgg taaagctcaa gaagttccag aagcaatccg taaagcagta gatgatgcta
    59341 agaaaaactt gatcgaagtt cctatggttg gaacaacaat cccacacgaa gttctttcag
    59401 aattcggtgg agctaaagta ttgttgaaac ctgctgtaga aggttctgga gttgccgctg
    59461 gtggtgcagt tcgtgccgtt gtggaattgg caggtgtggc agatattaca tctaaatcac
    59521 ttggttctaa cactccaatc aacattgttc gtgcaactgt tgaaggtttg aaacaattga
    59581 aacgcgctga agaaattgct gcccttcgtg gtatttcagt ttctgatttg gcataagaaa
    59641 ggggataaaa tggctcaaat taaaattact ttgactaagt ctccaatcgg acgcattcca
    59701 tcacaacgta aaactgttgt agcacttgga cttggcaaat tgaacagctc tgttattaaa
    59761 gaagataacg ctgctatccg tggtatgatt acagcagtat ctcacttagt aacagttgaa
    59821 gaagtaaact aatgaagttt taggggatgt gcactgtacc atcccctaaa actagatata
    59881 gtcatctatg atgacatcgt ataggcgagt tgatggggga gacaaccttt tctcccttat
    59941 cggcgctagc attttacaaa agaggagaaa ataaaaatga aacttcatga attgaaacct
    60001 gcagaaggtt ctcgtaaagt acgtaaccgc gttggtcgtg gtacttcatc aggtaacggt
    60061 aaaacatctg gtcgtggtca aaaaggtcaa aaagctcgta gcggtggcgg agttcgcctt
    60121 ggttttgaag gtggacaaac tccattgttc cgtcgtcttc caaaacgtgg attcactaac
    60181 atcaacgcta aagaatacgc aattgtgaac cttgaccaat tgaacgtctt tgaagatggt
    60241 gctgaagtaa ctccagttgt tcttatcgaa gcaggaattg ttaaagctga aaagtcaggt
    60301 attaaaattc ttggtaacgg tgagttgact aagaaattga ctgtgaaagc agctaaattc
    60361 tctaaatcag ctgaagaagc tatcactgct aaaggtggtt cagtagaagt catctaagag
    60421 aggtgaccta tgttttttaa attattaaga gaagctctta aagtcaagca ggttcgatca
    60481 aaaattttat ttacaatttt tatcgttttg gtctttcgta tcggaactag cattacagtt
    60541 cctggtgtga atgccaatag cttgaatgct ttaagtggat tatccttctt aaacatgttg
    60601 agcttggtgt cggggaatgc cctaaaaaac ttttcgattt ttgccctagg agttagtccc
    60661 tatatcaccg cttctattgt tgtccaactc ttgcaaatgg atattttacc caagtttgta
    60721 gagtggggta aacaagggga agtaggtcga agaaaattga atcaagctac tcgttatatt
    60781 gctctagttc tcgcttttgt gcaatctatc gggattacag ctggttttaa taccttggct
    60841 ggagctcaat tgattaaaac tgctttaact ccacaagttt ttctgacgat tggtatcatc
    60901 ttaacagctg gtagtatgat tgtcacttgg ttgggtgagc aaattacaga taagggatac
    60961 ggaaacggtg tttccatgat tatctttgcc gggattgttt cctcaattcc agagatgatt
    61021 cagggcatct atgtggacta ctttgtgaac gtcccaagta gccgtatcac ttcatctatc
    61081 attttcgtaa tcattttgat tattactgta ttgttgatta tttactttac aacttatgtt
    61141 caacaagcag aatacaaaat tccaatccaa tatactaagg ttgcacaagg tgctccatct
    61201 agctcttacc ttccgttaaa ggtaaaccct gctggagtta tccctgttat ctttgccagt
    61261 tcgattactg cagcgcctgc ggctattctt cagtttttga gtgccacagg tcatgattgg
    61321 gcttgggtaa gggtagcaca agagatgttg gcaactactt ctccaactgg tattgccatg
    61381 tatgctttgt tgattattct ctttacattc ttctatacgt ttgtacagat taatcctgaa
    61441 aaagcagcag agagcctaca aaagagtggt gcctatatcc atggagttcg tcctggtaaa
    61501 ggtacagaag aatatatgtc taaacttctt cgtcgtcttg caactgttgg ttccctcttc
    61561 cttggtgtga tttccatttt accgattgca gctaaagatg tatttggtct ttctgatgtt
    61621 gttgcctttg gtggaacaag tctcttgatc attatctcta caggtatcga aggaatcaag
    61681 caattggaag gttacctatt gaaacgtaag tatgttggtt tcatggacag aacagaataa
    61741 aagtatttac tgaatcagta aatactgagg gagtggaggt ttaaactctg acatttgtaa
    61801 gagttggatc tcccctcttc tattttgttt ttaaataggg gtgaaaagac tttttgcttc
    61861 tatttaaaaa taaaataagg agatcaaatc atgaatcttt tgattatggg cttacctggt
    61921 gcaggtaagg gaactcaagc agcaaaaatc gtagaacaat tccatgttgc acatatctca
    61981 acaggtgata tgttccgcgc tgcaatggca aatcaaactg aaatgggtgt tcttgctaag
    62041 tcatatattg acaagggtga attggttcct gacgaagtta caaatggaat cgtaaaagaa
    62101 tgcctttcac aagatgatat taaagaaaca ggattcttat tggatggtta cccacgtaca
    62161 attgaacaag ctcatgcctt ggacaaaaca ttggctgaac ttggcattga actagaaggt
    62221 attatcaata ttgaagtgaa ccctgacagc ctcttggaac gtttgagtgg ccgtatcatc
    62281 caccgcgtaa ctggagaaac tttccacaag gtctttaacc caccagttga ctataaagaa
    62341 gaagattact accaacgtga agatgataag cctgagacag taaaacgtcg tttggatgtt
    62401 aatattgctc aaggagaacc aatcattgct cactaccgtg ccaaaggttt ggttcatgac
    62461 atcgaaggta atcaagatat caatgatgtc ttctcagata ttgaaaaagt attgacaaat
    62521 ttgaaataaa gcgtttttcg cacttgcaaa aatccgctac aaatgttata ctgagatagt
    62581 ctgacttata attgttgtct ctgtgtctag aggcatcgaa tcgaaattta tggaggtgct
    62641 tttgcgtggc aaaagacgat gtgattgaag ttgaaggcaa agtagttgat acaatgccga
    62701 atgcaatgtt tacggttgaa cttgaaaatg gacatcagat tttagcaaca gtttctggta
    62761 aaattcgtaa aaactatatt cgtattttag cgggagatcg tgttactgtc gaaatgagtc
    62821 catatgactt gacacgtgga cgtatcactt accgctttaa ataatcgaaa aacttggagg
    62881 gataagaaat gaaagtaaga ccatcggtca aaccaatttg cgaatactgt aaagttattc
    62941 gtcgtaatgg tcgtgttatg gtaatttgcc cagcaaatcc aaaacacaaa caacgtcaag
    63001 gataagatag aaaggagaaa acatggctcg tattgctgga gttgatattc caaatgacaa
    63061 acgcgtagta atctcattga cttatgttta tggtatcgga cttgcaacat ctaagaaaat
    63121 tttggctgct gctggaatct cagaagatgt tcgtgtacgt gatcttacat cagatcaaga
    63181 agatgctatc cgtcgtgaag tggatgcaat caaagttgaa ggtgaccttc gtcgtgaagt
    63241 aaacttgaac atcaaacgtt tgatggaaat cggttcatac cgtggtatcc gtcaccgtcg
    63301 tggacttcct gtccgtggac aaaacactaa aaacaacgcc cgcactcgta aaggtaaagc
    63361 tgttgcgatt gctggtaaga aaaaataata taggaggtaa aagtcttggc taaaccaaca
    63421 cgtaaacgtc gtgtgaaaaa gaatatcgaa tctggtattg ctcatattca cgctacattt
    63481 aataacacta ttgttatgat tactgatgtg catggtaatg caattgcttg gtcatcagct
    63541 ggtgctcttg gtttcaaagg ttctcgtaaa tctacaccat tcgctgctca aatggcttct
    63601 gaagctgctg ctaaatctgc acaagaacac ggtcttaaat cagttgaagt tactgtaaaa
    63661 ggtccaggtt ctggtcgtga gtcagctatt cgtgcgcttg ctgccgctgg tcttgaagta
    63721 acagcaattc gtgatgtgac tccagtgcca cacaatggtg ctcgtcctcc aaaacgtcgc
    63781 cgtgtataat catcgcatta cactgctttt cgtttaagag ggagtaacta aatgatcgag
    63841 tttgaaaaac caaatataac aaaaattgat gaaaataaag attatggcaa gtttgtaatc
    63901 gaaccacttg aacgtggcta cggtacaact cttggtaact ctcttcgtcg tgtacttcta
    63961 gcttctctac caggagcagc tgtgacatct atcaacattg atggtgtgtt acatgagttt
    64021 gacacagttc caggtgttcg tgaagacgtt atgcaaatca ttctgaacat taaaggaatt
    64081 gcagtgaaat cgtacgttga agacgaaaaa atcatcgaac tggatgttga aggtcctgct
    64141 gaagtaacag ctggtgacat tttgacagat agcgatattg aaattgtaaa tccagatcat
    64201 tatctcttta caattggtga aggttcttct ctaaaagcga ctatgactgt taacagtggt
    64261 cgtggatatg tacctgctga tgaaaataaa aaggataatg caccagttgg aacacttgct
    64321 gtagattcta tttatacacc agttacaaaa gtcaactatc aagtggaacc tgctcgtgta
    64381 ggtagcaatg atggtttcga caaattaacc cttgaaatct tgacaaatgg aacaattatt
    64441 ccagaagatg ctttagggct ttcagcacgt attttgacag aacatcttga tttgtttaca
    64501 aatcttactg agattgctaa gtcaactgaa gtgatgaaag aagctgatac tgaatctgac
    64561 gaccgtattt tagatcgtac gattgaggaa ctggacttgt ctgtgcgttc atacaactgt
    64621 ttaaaacgtg ccggtatcaa tactgtgcat gatttgacag aaaaatctga agcagagatg
    64681 atgaaagtac gaaatcttgg acgcaagagt ttggaagaag tgaaactcaa actcattgat
    64741 ttgggtcttg gattaaaaga taaataaagg aggaatacat ggcttaccgt aaactaggac
    64801 gcactagctc acaacgtaaa gcaatgcttc gcgatttgac aactgacctt ttgatcaacg
    64861 aatcaatcgt gacaactgaa gctcgtgcta aagaaatccg taaaactgtt gaaaaaatga
    64921 ttactctagg taaacgtggt gatttgcatg cacgtcgtca agcagctgct ttcgtacgta
    64981 atgaaatcgc atctgaaaac tatgatgaag caactgataa gtacacttct actacagcac
    65041 ttcaaaaatt gttctcagaa atcgcacctc gttatgctga acgtaacggt ggatacactc
    65101 gtatccttaa aactgaacca cgtcgtggtg atgcagcgcc aatggcgatc atcgaattag
    65161 tataaaatca tcaattttgt tgagtgttat gatgatggag tcttgtgctc ttagtctagc
    65221 tctggtctac cgctaggatt tcggtcctag cgggaacact catcataagt tgggatagta
    65281 gacgcttgtt tacgaaattg tttttttctt aagaacaact tcgtaagcag gcgtttttga
    65341 gtattttcgt tagaattatg ctatactatt tgaaaagaat cctgtttaat gttaaggttt
    65401 cttattttaa gaagaattgg agtttactta tgaaagcgat tataactgtt gttggtaaag
    65461 ataaatctgg aattgttgca ggtgtttctg gtaaaattgc agaattagga ttgaatattg
    65521 acgatatctc tcaaactgta ttggatgaat attttacgat gatggctgtt gtatctagtg
    65581 atgaaaagca agattttacc tatcttcgta atgaatttga agcttttggg caaactttga
    65641 atgtaaaaat caatattcag agtgcagcga ttttcgaagc tatgtataat atctaggagg
    65701 tcatcatgga tattagacaa gttactgaaa ccatcgccat gattgaggag caaaacttcg
    65761 atattagaac cattaccatg gggatttctc ttttggactg tatcgatcca aatatcaatc
    65821 gtgctgcgga gaaaatctat caaaaaatta cgacaaaggc ggctaattta gtagctgttg
    65881 gtgatgaaat tgcggctgag ttgggaattc ctatcgttaa taagcgtgta tcggtgacac
    65941 ctatttctct gattggggca gcgacagatg cgacggacta cgtggttctg gcaaaagcgc
    66001 ttgataaggc tgcgaaagag attggtgtgg actttattgg tggtttttct gccttagtac
    66061 aaaaaggtta tcaaaaggga gatgagattc tcatcaattc cattcctcgc gctttggctg
    66121 agacggataa ggtctgctcg tcagtcaata tcggctcaac caagtctggt attaatatga
    66181 cggctgtggc agatatggga cgaattatca aggaaacagc aaatctttca gatatgggag
    66241 tggccaagtt ggttgtattc gctaatgctg ttgaggacaa tccatttatg gcgggtgcct
    66301 ttcatggtgt tggggaagca gatgttatca tcaatgtcgg agtttctggt cctggtgttg
    66361 tgaaacgtgc tttggaaaaa gttcgtggac agagctttga tgtagtagcc gaaacagtta
    66421 agaaaactgc ctttaaaatc actcgtatcg gtcaattggt tggtcaaatg gccagtgaga
    66481 gactgggtgt ggagtttggt attgtggact tgagtttggc accaacccct gcggttggag
    66541 actctgtggc acgtgtcctt gaggaaatgg ggctagaaac agttggcacg catggaacga
    66601 cagctgcctt ggccctcttg aacgaccaag ttaaaaaggg tggagtgatg gcctgtaacc
    66661 aggtcggtgg tctatctggt gcctttatcc ctgtttctga ggatgaagga atgattgctg
    66721 cagtgcaaaa tggctctctt aatttagaaa aactagaagc tatgacggct atctgttctg
    66781 ttggattgga tatgattgcc atcccagaag atacgcctgc tgaaactatt gcggctatga
    66841 ttgcggatga agcagcaatc ggtgttatca acatgaaaac aacagctgtt cgtatcattc
    66901 ccaaaggaag agaaggcgat atgattgagt ttggtggtct attaggaact gcacccgtta
    66961 tgaaggttaa tggggcttcg tctgtcgact tcatctctcg cggtggacaa atcccagcac
    67021 caattcatag ttttaaaaat taagaaaata ggagaaattt taagttctat ttaagattag
    67081 atgtgtatac tataatcatt aaataaagac ctcctaatat tatttgaaac agataacact
    67141 gaattagttt gaatttgatt ttcatctaat atctttattt aatgaactcc taaacttttt
    67201 cataataatc tccttcaaaa gtcgcctgta tgggtggctt ttattttatc attcatgata
    67261 taatagaagc aaacggagga cggaaaatgg taaaagtacg attgtatttg gtacgtcatg
    67321 gcaagaccat gtttaacacg attggtcgcg cgcaaggttg gagcgatact cccttaactg
    67381 ctgaaggtga acgagggatt caagagttag gaatcggttt gcgagaatct gatctacagt
    67441 ttgagcgcgc ttattcgagt gattctggtc gtaccattca gaccatggga attatacttg
    67501 aagaacttgg cttgcagggg aaaatccctt atcgcatgga caagcgtatc agagaatggt
    67561 gtttcggtag ttttgatgga gcctatgatg gcgatctttt catgggcatt attcctcgta
    67621 tctttaatgt ggaccacgtt caccaattgt cttatgctga actggctgag ggcttggtag
    67681 aggtcgatac agctggttgg gctgaaggtt gggaaaaact cagtggccga atcaaggaag
    67741 gctttgaaat aattgcaaaa gaaatggaag atcaaggtgg aggtaacgcc cttgttgtca
    67801 gccatggaat gactattgga accattgttt atctgattaa tggcatgcat ccgcatggtc
    67861 tagataatgg tagcgtgacg attcttgaat atgaggacgg tcagtttagg gttgaagttg
    67921 tcggtgaccg tagttaccga gagctaggac gtgagaagat ggaagaaggt tctatttaat
    67981 cagtctagac ttgcttgcca tgagctaggg atttgataag aatatcaaga taagaaaaaa
    68041 cagccgaggg tactcctttc ggctgttttt gatgtggaaa actaaagtgt aatgctattg
    68101 cttttagaga ttttcataaa caagagcaag gaacctactg ttagaacagt caggatagtt
    68161 gacaaggctg cagctacacc gtaatttcct ctgagaacct ctgtataaat agctacagtc
    68221 attgttcttg ttttgacatt gtagaggagg atagaagtag agagttctga aatcagtgtg
    68281 acccaagata ggatggctcc agaaataata tccgatagca tcattggagt tgtaatctta
    68341 gcaaagatat tgagacgact acttcctaag ctttcagcag cttcttcaat acttggtgct
    68401 atttgttgta agctagcaac agatgagcga atagtataag gtaattttct ggcagataga
    68461 gacataatca agatgaaagc agtccctgta atcataagaa atccacttcc aaatagacca
    68521 gagaaatgaa ggcaatccct agaacggttc ctggtacaat ataaggtacc atactgaggc
    68581 tgtcaattaa gtttgtaaac aaattccgtt ttctaacggc taggtaggag ataaatgtcg
    68641 taaatagaac aactagaact aaggcaatca aagggatacg aatggtattg aaaatagcag
    68701 atcccatacg attgaaagct agcttgtaac tgtttggaga ataaccttta acaaatacca
    68761 tacctgatgt ttttaggaaa gaggtataaa ttaagtagat ttgaggtaaa acagagataa
    68821 agataattcc gtagactgtt gcataaatgg cagccatttt tccttttgta gtttttttag
    68881 gctcaattgg atggagcaga ttcatgctga aactgtagcg gtttgcaatg tgtttttgga
    68941 taaggaaaat tgccaaggca atgataatcg ccataattgc aaaagcagaa tttcctccaa
    69001 cctcgctaat aaattgggta taaatcagga cagggaaagt ccgataccct tcgccaatca
    69061 acataggcgt tccaaagtct gagaatgctc tcataaatac aagcaaggag ctgctagtaa
    69121 ggttggaact aggagaggta aaacaaccgt tacgataggt ttaaatccga aggaccccat
    69181 gctttcagct gcttcaagta gagaattgtc aatactgttc attgttccag caacatatag
    69241 aaataccagt gggaatagtt gcagtgtaaa gacaagtaca attcctttga atccataaat
    69301 atcgatagct ggaagataaa gggcatttgt caaaaattta gtgatgacct catttcgtcc
    69361 cagcaagaga atccaggagt aggctcctac gaaaggagct gacatggaag caatgataat
    69421 caatatttgt agaaatttct tccccttgaa gtcatacata gagaagagat aagctaatag
    69481 ggttcctaca actaaggaag tgacagtagc ggtaatggaa accctgaaac tgttgactag
    69541 tgtctcagag tagtaggctt tactaaagaa agtgacaaaa ttagctagtg agaattgtcc
    69601 ttcatgtata agtgcttgct tgagcacggt aacgatagga taaacgagaa agacaagata
    69661 ggtaagaaag aggaagaaag aggaggctgt ccaaatattt agttttttac attccatggt
    69721 tgactccttt tatcaggttt tgggaaccat ctgcagaaaa gatgtttaat ttttgcgtat
    69781 tgattcgtag acgaatacga ttgccttttt gtagatcttc ttcaaaagtt gattcttcac
    69841 taacttgaat ttttgaggca aaacctgtct caatgaaata ctccgtattt agtccaagat
    69901 agacgctatc gctaatagtt ccttcgatat ctccagattc atctttgata aactcttcgg
    69961 gacgaatgct tacatgaata gcttgctcct caacctgatc aagagctagc attcgaaggg
    70021 catagccatc tgaaaagacg atataagcgc cgtcgctccg tttttcaaga ttggcaggga
    70081 taatatttgt gcgtccgata aaggttgcca caaactcatt agctggttta tgatagagtt
    70141 cttttggtcg gccgatttgt tggatcaccc catctttcat aacagcaatt tggtctgaaa
    70201 tagccatggc ttcttcttgg tcgtgggtta cataaacagt tgtaattccc acttcgtgtt
    70261 ggatttctcg gatggtttga cgcatatcca agcgaagttt ggcctccaga ttactaagtg
    70321 gctcgtccat gaggagaaca cttggattaa ccgctaaggc gcatgccaag gtgacacgtt
    70381 gttgttgtcc accactgagt ttatcgggct ttcgatccgc atattgagca atttgcatga
    70441 gttcaagata cttgttggtc tgttgaatca attcttcttt tggaaccttc ttttgcataa
    70501 gaccaaaagc aacgttgtct cggacagtca aatgtgggaa aatagcgtag ttttggaaaa
    70561 ccagcccgat attgcgtttg ctgggttcca tattattgat ttttgtatca tcgaagtaaa
    70621 attctccatc tttgatactg ttgaaacctg caatcatacg aagaagggtc gttttcccac
    70681 atcctgaagc tccaagaagg gtaaagagac ttccttttgg aattgtaatg ttcaaattct
    70741 caataacagg gacatcgtgg tagatttttt tggcgttaat aatttcgatc tcactcatag
    70801 tgaacctctt ttactgttta gattggatat ctgtaaagac ttcgttgtat ttcttaacga
    70861 tatctgattt attcttgatg acataatcat aatcttaagt gagtgttttg attttgtcaa
    70921 ttggtttcat gttttcgctt gttttagcat ttttacgaac aggacggtta gtagtggttg
    70981 taccaagtgt atcttgtact tcttgagaga taataaaatc gataaatttc ttggcatttt
    71041 ccatattttt agctttttta acgatagcag cactagaagg taggaagacg gttccttctt
    71101 ttggatagac taccttaatg ttagctccgt catttaagag tttaactgct ggatcttcat
    71161 aagagagacc aacagtcatt tctccatcag cgactgcttt atagacacca gatgaacttg
    71221 aaccgatttt atagtatatt gaaactagaa tagtacacat ctacttctaa aacattgtta
    71281 gaaatcgatt tgactgtcct gattaatttg tcctgttctt atttcatttt actataccat
    71341 caataagtgt gaaaagatct tttacataag accaagcctt atcatctttg taaccacctt
    71401 gagcttgtag catatttgtt aattgagcaa aggcgctaga agagtttgct gggtcagcag
    71461 ttgcgatttt tccttttagt tcaggtttga gaaggtcgct atatccttcg atgttcatgc
    71521 ctttagttaa atcagggtgg acgattaaaa cactaccatc tagtgtataa ggagtagaga
    71581 agccagttgt gttttgatat tctttgataa cattatcatt ttcttttgaa atatagtttt
    71641 caaagagttc tccgtgggta gcatattgtg tataagaacc accaaagata acatcagcta
    71701 caggaacttc tttttctgac tctagttttt tgaaaagttc tccagtacca gcttgaatca
    71761 gttctatttt gataccatat ttttcttcaa aggcaggaat agttgctcca attaagcctt
    71821 ctgagtttgg tcaataaacg actagcgaac caccgtctcc tttatcagat gaactgtcat
    71881 cggcagattc attagaagaa caagcagcat aatacatcca tttctttttc atgatggata
    71941 cctccgttgt gttatttaag tttattttaa aacaatgtaa gcgtttttaa aacctacaat
    72001 tctattctat agtgtattga atctataaca gtacactttg actgctaaaa tatttctata
    72061 aattaatttg actttcctga tagagatgtt cacatcttat ttcaattcac tatattagag
    72121 taaaattctc tacaaaaaga agaatagcct attttactat tcttccgagt gatttcaatt
    72181 tctttgggga aatatggaga tactttttaa atactttggc aaaatattta tagtctgaaa
    72241 atccaacttg gtcagagata tcgcttaaag aggagttggg agattcagcc atcttatcta
    72301 tagcttgttt caggcgatat tgtaagatat attcatttag agtcatgggg aagtcttctt
    72361 tgataacctt atatagatgc ttgttatctg caaatagcta gagcatttca aggaaataaa
    72421 ctagaaataa caattaatat ggtggttcag aaataccttt tgataatcaa taagatcttc
    72481 aggatgaagt gcgttgactc catccatttc atatttccga tttaataaac gatatttgtt
    72541 ttcaccaaat tgatgaaaag ggagtagttg aacttggtcg atatttaatg agttaaatag
    72601 agtagcgaat ttttctgcat cctctaaact attgttaaaa ttaggaataa ctgggattct
    72661 taaaacgata gttttatttt gagaaaaagc ataatgaatg tttttaataa tcatttgatt
    72721 aaaaacccca gtcacttttt tatgttttat agaattataa tgttttaggt ctgtgtagat
    72781 aaaatccaca tattgaatta aatcaataaa tttttcatga tcaacaaagg cagtagtttc
    72841 aatggcagtg tgtatgtgat gttctttagc tgattttaag atggctttag caaattcaaa
    72901 ctgagcaaat atttcacctc ctgataaagt taaacctcca ccggattctt cgtaaaattc
    72961 tttgtctttt aatacctctg taataatttc ttctacagtc ttttcttcac cgactaaggt
    73021 gaatttctct cgttgagcat ctttcatttt ttcaggtttc attctttgag attcaggatt
    73081 agaacaccat ggacagcgca gaggacatcc ttttaaaaaa acagttgtac gaatacccgg
    73141 accgtcatga attgaaaagt gttgaatatt aaaaataatt cctttagata tttccataag
    73201 agttcctcct cttcataagt ctatcctatc acaaaaacga aagaaaaaca attacgaacg
    73261 aaaggttaat ttgttgtttt ttgcttttta ttttggtaga ataaaacgga ggtgtaaaat
    73321 gaaaagattg gaacaaatta ttaaattagt atcagaatat gaaaagatcg acgttaatac
    73381 attatcggaa aaattaaatg tatcgaaagt aacgattaga aaagatttag ataaattaga
    73441 gtcaaaaggt ttattacaca gagagcatgg atatgctgta ttaaatagtg gagatgactt
    73501 aaatgtacgt ttgtcaatta actatgaaat taagagaaaa attgttcagg aagcagtaaa
    73561 attggtgtca gataatgaaa caataatgat agaatctgga tcgacctgtg ctttacttgc
    73621 tgaggaaatt tgcaagcaaa aaagaaatgt tacgattgta acaaattcat tttttatagc
    73681 aaattttgtg agagcttatg attcatgtcg tattattgtt cttggtggag agtttcagaa
    73741 ggattcacag gttactgtgg gacctttatt aaaagaaatg atacagactt ttcatgtgcg
    73801 tcaagctttt gttgggacag atggctacga taaagagatg ggctttacag gaaaagattt
    73861 aatgcgcagt gaggtagttc aatatatttc agcagcgtcg gataaagtca ttgtgctaac
    73921 tgactcaagt aaatttgata aaaggggtac agtaagaaga tttgctttaa gtcaagtcta
    73981 tgaagtaata acagacgaaa aactttctaa acaaaatatg gctacattag aaaatgctgg
    74041 gataatggtt aaggtagttt cgtaagaggt taagtgtatg aatcaagata ggaataaact
    74101 gctctctaaa attgcttatc tgtattatat tgaaaactta aatcagtcac aaatagcagc
    74161 aaaattagga atttatagaa cctctattag tagaatgtta acagaagcaa ggaatgcagg
    74221 aattgttaaa attgaaatag agaattttga taccaatatg tttaagttgg aaaattatgt
    74281 aaaagaaaaa tatggtctgg aaagtttaga aattattcca aatgaatttg atgataatcc
    74341 aacaatttta tctgaaagaa tttctcaagt tgcagcaggt gtccttagga atctaattga
    74401 tgataatatg aaaattggct tttcttgggg gaaaagttta agtaatttag tagatttaat
    74461 tcacagtaaa agtgtccgaa atgttcactt ctatcctcta gcaggtggtc ctagtcacat
    74521 acacgctaaa taccatgtga atacactgat ttatgaaatg tctagaaaat ttcatggaga
    74581 gtgtacattt atgaatgcaa cgattgtgca agaaaataaa ttgttagcag atggtatttt
    74641 gcaatcaaga tattttgaaa atttgaaaaa tagttggaaa gatttagata tagctgtagt
    74701 cggaattggt gattttagca ataaaggaaa gcatcaatgg ttagacatgc ttacagagga
    74761 tgactttaaa gaattgacca aagttaaaac tgtaggagaa atttgttgtc gattttttga
    74821 ttcaaaaggt aaagaagtct atgaaaactt acaggaaaga acgatagcaa tctctttgga
    74881 agatttaaaa aatattcctc aaagtttagc tgttgcttac ggtgatacga aagtatcttc
    74941 gattctttct gtcttgcgtg ctaatttagt aaatcatttg attacagaca aaaatacaat
    75001 tttaaaagtt ttggaagaag atggggattt gacttttaga gagattctag gtgagtgaaa
    75061 atgatagact gattcagttt atcgtttttc tttttagttg attgcacatt tgtgcttata
    75121 taaacaaaaa tagtttatct g
//
LOCUS       DAVMJI010000007        71255 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.007, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000007 DAVMJI010000000
VERSION     DAVMJI010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 71255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71255
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.007"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(15..311)
                     /locus_tag="VYR58_000527"
     CDS             complement(15..311)
                     /locus_tag="VYR58_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621741.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYKLTEYSKMK"
     gene            complement(295..2427)
                     /gene="pfbA"
                     /locus_tag="VYR58_000528"
     CDS             complement(295..2427)
                     /gene="pfbA"
                     /locus_tag="VYR58_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV3621742.1"
                     /translation="MLKIVKKLEVLMKYFVPNKVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SVIKSNANGKEPVIRDSDGNFNIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNGEF
                     NSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSN
                     KIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3544..4770)
                     /locus_tag="VYR58_000529"
     CDS             complement(3544..4770)
                     /locus_tag="VYR58_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV3621743.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4813..5505)
                     /locus_tag="VYR58_000530"
     CDS             complement(4813..5505)
                     /locus_tag="VYR58_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV3621744.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNCRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5678..7429)
                     /locus_tag="VYR58_000531"
     CDS             complement(5678..7429)
                     /locus_tag="VYR58_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621745.1"
                     /translation="MQNKQEQWAVLKRLMSYLKSYGLLIFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKVLILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(7419..9164)
                     /locus_tag="VYR58_000532"
     CDS             complement(7419..9164)
                     /locus_tag="VYR58_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3621746.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALILVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9370..9747)
                     /locus_tag="VYR58_000533"
     CDS             complement(9370..9747)
                     /locus_tag="VYR58_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV3621747.1"
                     /translation="MKRLIDGKPTLLIKNGNIDPEACRSVGLSASDVSLKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9819..10275)
                     /locus_tag="VYR58_000534"
                     /pseudo
     CDS             complement(9819..10275)
                     /locus_tag="VYR58_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10409..11236
                     /gene="xth"
                     /locus_tag="VYR58_000535"
     CDS             10409..11236
                     /gene="xth"
                     /locus_tag="VYR58_000535"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV3621748.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11248..11346
                     /locus_tag="VYR58_000536"
     CDS             11248..11346
                     /locus_tag="VYR58_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV3621749.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            11391..11630
                     /locus_tag="VYR58_000537"
     CDS             11391..11630
                     /locus_tag="VYR58_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV3621750.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12013..12108
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12508..13089
                     /locus_tag="VYR58_000538"
     CDS             12508..13089
                     /locus_tag="VYR58_000538"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV3621751.1"
                     /translation="MKLLEERILKDGHILDDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVLFKEADL"
     gene            13089..14351
                     /locus_tag="VYR58_000539"
     CDS             13089..14351
                     /locus_tag="VYR58_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV3621752.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIFVASLLAIVLNAVLNHKKK"
     gene            complement(14402..14863)
                     /locus_tag="VYR58_000540"
     CDS             complement(14402..14863)
                     /locus_tag="VYR58_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV3621753.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14860..15624)
                     /locus_tag="VYR58_000541"
     CDS             complement(14860..15624)
                     /locus_tag="VYR58_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEV3621754.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(15805..16209)
                     /locus_tag="VYR58_000542"
     CDS             complement(15805..16209)
                     /locus_tag="VYR58_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV3621755.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(16279..17760)
                     /locus_tag="VYR58_000543"
     CDS             complement(16279..17760)
                     /locus_tag="VYR58_000543"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV3621756.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKAQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGISLD"
     gene            complement(17779..18957)
                     /locus_tag="VYR58_000544"
     CDS             complement(17779..18957)
                     /locus_tag="VYR58_000544"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV3621757.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19121..20128
                     /gene="galR"
                     /locus_tag="VYR58_000545"
     CDS             19121..20128
                     /gene="galR"
                     /locus_tag="VYR58_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV3621758.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20174..21211)
                     /locus_tag="VYR58_000546"
     CDS             complement(20174..21211)
                     /locus_tag="VYR58_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV3621759.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21212..21565)
                     /locus_tag="VYR58_000547"
     CDS             complement(21212..21565)
                     /locus_tag="VYR58_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV3621760.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21809..22699)
                     /locus_tag="VYR58_000548"
     CDS             complement(21809..22699)
                     /locus_tag="VYR58_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV3621761.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22832..23368
                     /locus_tag="VYR58_000549"
     CDS             22832..23368
                     /locus_tag="VYR58_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV3621762.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTGQEVVQFYLDLLIPKN"
     gene            complement(23534..24340)
                     /locus_tag="VYR58_000550"
     CDS             complement(23534..24340)
                     /locus_tag="VYR58_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV3621763.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24685..26205)
                     /locus_tag="VYR58_000551"
     CDS             complement(24685..26205)
                     /locus_tag="VYR58_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV3621764.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(26198..26926)
                     /locus_tag="VYR58_000552"
     CDS             complement(26198..26926)
                     /locus_tag="VYR58_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621765.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            complement(26941..27705)
                     /locus_tag="VYR58_000553"
     CDS             complement(26941..27705)
                     /locus_tag="VYR58_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV3621766.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTETFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27709..28152)
                     /locus_tag="VYR58_000554"
     CDS             complement(27709..28152)
                     /locus_tag="VYR58_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV3621767.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            complement(28834..29130)
                     /locus_tag="VYR58_000555"
     CDS             complement(28834..29130)
                     /locus_tag="VYR58_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV3621768.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            complement(29152..30216)
                     /gene="pepA"
                     /locus_tag="VYR58_000556"
     CDS             complement(29152..30216)
                     /gene="pepA"
                     /locus_tag="VYR58_000556"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV3621769.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30617..31318
                     /locus_tag="VYR58_000557"
     CDS             30617..31318
                     /locus_tag="VYR58_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV3621770.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHGLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            31741..32700
                     /locus_tag="VYR58_000558"
     CDS             31741..32700
                     /locus_tag="VYR58_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3621771.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32690..33646
                     /locus_tag="VYR58_000559"
     CDS             32690..33646
                     /locus_tag="VYR58_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV3621772.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYILLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILIGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            33643..34395
                     /locus_tag="VYR58_000560"
     CDS             33643..34395
                     /locus_tag="VYR58_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3621773.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            34491..35456
                     /locus_tag="VYR58_000561"
     CDS             34491..35456
                     /locus_tag="VYR58_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV3621774.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35681..35923)
                     /gene="yidD"
                     /locus_tag="VYR58_000562"
     CDS             complement(35681..35923)
                     /gene="yidD"
                     /locus_tag="VYR58_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV3621775.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFDLTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(35923..36645)
                     /locus_tag="VYR58_000563"
     CDS             complement(35923..36645)
                     /locus_tag="VYR58_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV3621776.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36632..37201)
                     /locus_tag="VYR58_000564"
     CDS             complement(36632..37201)
                     /locus_tag="VYR58_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV3621777.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37220..37948)
                     /locus_tag="VYR58_000565"
     CDS             complement(37220..37948)
                     /locus_tag="VYR58_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV3621778.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(37948..38688)
                     /gene="xerD"
                     /locus_tag="VYR58_000566"
     CDS             complement(37948..38688)
                     /gene="xerD"
                     /locus_tag="VYR58_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV3621779.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38679..39140)
                     /locus_tag="VYR58_000567"
     CDS             complement(38679..39140)
                     /locus_tag="VYR58_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV3621780.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39137..39658)
                     /locus_tag="VYR58_000568"
     CDS             complement(39137..39658)
                     /locus_tag="VYR58_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV3621781.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39634..40605)
                     /locus_tag="VYR58_000569"
     CDS             complement(39634..40605)
                     /locus_tag="VYR58_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV3621782.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40602..41396)
                     /gene="racE"
                     /locus_tag="VYR58_000570"
     CDS             complement(40602..41396)
                     /gene="racE"
                     /locus_tag="VYR58_000570"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV3621783.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41603..41851)
                     /locus_tag="VYR58_000571"
     CDS             complement(41603..41851)
                     /locus_tag="VYR58_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV3621784.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42107..43732)
                     /gene="treC"
                     /locus_tag="VYR58_000572"
     CDS             complement(42107..43732)
                     /gene="treC"
                     /locus_tag="VYR58_000572"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV3621785.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(43910..45877)
                     /gene="treP"
                     /locus_tag="VYR58_000573"
     CDS             complement(43910..45877)
                     /gene="treP"
                     /locus_tag="VYR58_000573"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV3621786.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVSHELVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETLVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            46062..46772
                     /gene="treR"
                     /locus_tag="VYR58_000574"
     CDS             46062..46772
                     /gene="treR"
                     /locus_tag="VYR58_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV3621787.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(46805..47608)
                     /locus_tag="VYR58_000575"
     CDS             complement(46805..47608)
                     /locus_tag="VYR58_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3621788.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(47621..48514)
                     /locus_tag="VYR58_000576"
     CDS             complement(47621..48514)
                     /locus_tag="VYR58_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3621789.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIVEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            complement(48526..49257)
                     /locus_tag="VYR58_000577"
     CDS             complement(48526..49257)
                     /locus_tag="VYR58_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV3621790.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSEPNSVV
                     QKDEAKRLLKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISLTMETVKQ
                     VSIKHKVPVFGGSTEMIAVGGLYNYGTNYEELGRQTARMLIHVLKGEKPENIAVELPE
                     KLELHTNQEMADALGIDISKLEGKE"
     gene            complement(49747..50673)
                     /locus_tag="VYR58_000578"
     CDS             complement(49747..50673)
                     /locus_tag="VYR58_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621791.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(50684..51751)
                     /locus_tag="VYR58_000579"
     CDS             complement(50684..51751)
                     /locus_tag="VYR58_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621792.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            complement(51760..52686)
                     /locus_tag="VYR58_000580"
     CDS             complement(51760..52686)
                     /locus_tag="VYR58_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3621793.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            complement(52686..54182)
                     /locus_tag="VYR58_000581"
     CDS             complement(52686..54182)
                     /locus_tag="VYR58_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3621794.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            complement(54249..56228)
                     /locus_tag="VYR58_000582"
     CDS             complement(54249..56228)
                     /locus_tag="VYR58_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV3621795.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            complement(56810..58156)
                     /locus_tag="VYR58_000583"
     CDS             complement(56810..58156)
                     /locus_tag="VYR58_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HEV3621796.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     LISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDIISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFHHLFLH
                     VVGNCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPGRKASLMMH"
     gene            complement(58621..59814)
                     /locus_tag="VYR58_000584"
     CDS             complement(58621..59814)
                     /locus_tag="VYR58_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV3621797.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVFCLYIIS
                     LIFTGDMKSILQKMGEHSMLLLFLGYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(59952..61394)
                     /gene="gtfA"
                     /locus_tag="VYR58_000585"
     CDS             complement(59952..61394)
                     /gene="gtfA"
                     /locus_tag="VYR58_000585"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV3621798.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            complement(61671..61751)
                     /locus_tag="VYR58_000586"
                     /pseudo
     CDS             complement(61671..61751)
                     /locus_tag="VYR58_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(61752..62585)
                     /locus_tag="VYR58_000587"
     CDS             complement(61752..62585)
                     /locus_tag="VYR58_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV3621799.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     VFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            complement(62599..63465)
                     /locus_tag="VYR58_000588"
     CDS             complement(62599..63465)
                     /locus_tag="VYR58_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV3621800.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(63479..64738)
                     /locus_tag="VYR58_000589"
     CDS             complement(63479..64738)
                     /locus_tag="VYR58_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV3621801.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNAYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTSFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            complement(64830..66992)
                     /locus_tag="VYR58_000590"
     CDS             complement(64830..66992)
                     /locus_tag="VYR58_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV3621802.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            67100..67960
                     /locus_tag="VYR58_000591"
     CDS             67100..67960
                     /locus_tag="VYR58_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV3621803.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKDKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            67957..68892
                     /locus_tag="VYR58_000592"
     CDS             67957..68892
                     /locus_tag="VYR58_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV3621804.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLQQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            69038..70344
                     /locus_tag="VYR58_000593"
                     /pseudo
     CDS             69038..70344
                     /locus_tag="VYR58_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(70448..70535)
                     /locus_tag="VYR58_000594"
     tRNA            complement(70448..70535)
                     /locus_tag="VYR58_000594"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(70499..70501),aa:Ser,seq:gct)
     gene            complement(70542..70615)
                     /locus_tag="VYR58_000595"
     tRNA            complement(70542..70615)
                     /locus_tag="VYR58_000595"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(70579..70581),aa:Ile,seq:gat)
     gene            complement(70651..70721)
                     /locus_tag="VYR58_000596"
     tRNA            complement(70651..70721)
                     /locus_tag="VYR58_000596"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(70687..70689),aa:Gly,seq:tcc)
     gene            complement(70741..70813)
                     /locus_tag="VYR58_000597"
     tRNA            complement(70741..70813)
                     /locus_tag="VYR58_000597"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(70778..70780),aa:Phe,seq:gaa)
     gene            complement(70817..70890)
                     /locus_tag="VYR58_000598"
     tRNA            complement(70817..70890)
                     /locus_tag="VYR58_000598"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(70854..70856),aa:Met,seq:cat)
     gene            complement(70901..70990)
                     /locus_tag="VYR58_000599"
     tRNA            complement(70901..70990)
                     /locus_tag="VYR58_000599"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(70952..70954),aa:Ser,seq:tga)
     gene            complement(71073..71146)
                     /locus_tag="VYR58_000600"
     tRNA            complement(71073..71146)
                     /locus_tag="VYR58_000600"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(71110..71112),aa:Ile,seq:gat)
     gene            complement(71181..71251)
                     /locus_tag="VYR58_000601"
     tRNA            complement(71181..71251)
                     /locus_tag="VYR58_000601"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(71217..71219),aa:Gly,seq:tcc)
BASE COUNT        21346 a        15929 c        13135 g        20845 t
ORIGIN      
        1 gatttgtcct attattattt cattttacta tactctgtta atttatatga gtttaaaccg
       61 atttcatctt taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct
      121 ttacaattaa ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct
      181 atctcctctt tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt
      241 tgtgaaccta caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt
      301 atctttacca taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt
      361 taagaatagt tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac
      421 tatttcttta gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata
      481 gtttacttct tctgtcttat tatcttgttt attgtcgatc ttgtcattca tttgtctatt
      541 atctttactt gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt
      601 agattgtttt tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac
      661 aatattgaaa ttaccatcgc tatcacgtat aacaggttct ttcccatttg cattagattt
      721 gatgactgat atatacttac cggataaatt ataaaattgg ttatttaaaa cggttatttt
      781 accctttgaa tcctcaataa caattccttc tttaccaccg aatatactat tctctgagac
      841 tactaaatta tcactaactc gtaataattc aatatttggt tgttctgttt ccttagaatt
      901 attattaatt acattttttg ttacagtaat atctgatact tttcctaaat attctgcact
      961 atcttttgca actcgtatcg cttttgtttt aggatcggca atattaaata tattttcggc
     1021 gataaccacc tgtttattta aatctaatag gtctttagtg tttttatagc tataagcatt
     1081 tactaaagct gctccgtttt ctcgataatg tacactctct cctttaactt tcttatcaaa
     1141 gcgatttcct ttgattaata catcagtgaa tcctgtaaaa cgtacacctg catacatcat
     1201 gttatcaaaa tgattattta aaattttaat attagagggg ttctgtgtcg acaatgtttg
     1261 atagtgtgta ccaattgctg ttactaattc cccagattta tcacttttgc caaaatagga
     1321 attttgaata gtcacatttt cagatttttt cccatcatca ttcaaggcat aaggaaaacc
     1381 ttttctagtt aatggttcaa tctgaatgct ctccttactt atgatttgcc catccttcat
     1441 cgttttgggt aaggcttgcc caagaaaacg agaattatca actaatacat ttttcgaacc
     1501 tgcaatttga atagcatgcc cttgataact atccttgaat gttacatttt ttatagttac
     1561 gttatttgaa ttcccaatag caaatgcacc tgaagaattt ataagtggta gattttttgc
     1621 tttagttcct tcttcattca aagcaccgtt catatcaatc gtaccaccag aataactaat
     1681 atcttctgtt gggccccatt ctacttgcgc accatcatct gtaaataaac ctgtcataaa
     1741 aacaatggaa gggtgattct taatatttat accatttaga attgtagctt tctcattcaa
     1801 ttctaagtgt gtatgacttt ttaaaaaaac aatttctttt actaaataag ttccttcagg
     1861 aaaatataca tttcctccac ctagcccttg agctgcagca tctattgcat cttgaattgc
     1921 ttgtcgatca tcatgaatcc catcacctac cgcaccataa tcttttacac ttaaagcagt
     1981 atcttcaaat tcttttttga taattctgtc acttataaca tcttccttat aactcttatt
     2041 ttcattagta gatgttactg tagattcaac tgttctgttg tctaattgtg aattggaacg
     2101 aatagtacca ttagagctga tactattaac acttaacgaa ttatctaaac cattagtggt
     2161 tgaattagag gcaatcattt cagcagaacg attttgatta acagttggtg aattatctaa
     2221 atcattagta attgcattag aagactcttt tgtagccatc ggtgaagaac tagtaacaac
     2281 ttcatccgat aaaatacctt ggcttcccaa aattgaaatt gccaatagta ccgagcaagt
     2341 ccccaccttt aatttacgaa tactgaatac cttattagga acaaaatatt tcatcagaac
     2401 ctccaatttt tttactattt ttaacaattg attattactt ttcttaaaat agatagaatg
     2461 acaccgctgt cattatcttt atcatatatt ttccaaattg aattgtcaag gaataacaca
     2521 agaaaatatt aaaatttata ctcttcggaa atctcttcaa actaggtcag tgccgccttg
     2581 ccctaagtct aggttactga cttggtcagt tctatagtag actgaaacta taatagtaca
     2641 cctctacttc taaaacattg ttagaaatcg atttaactgt cccgattaat ttgtcctatt
     2701 cttatttcat tttattatat ctacaacctc aaagcagggt tttgagctat ctatggccaa
     2761 cttcctagtt tgctctttag ccttccattc aaaagtgatg ctatctttct tagcttgaat
     2821 ataaaatatc ccatttacta tatttaaatt tgttgatatg ttgtaaatta taaatgaaag
     2881 aacaaatatc ttgtcataca agcattcgcc agggatattt acatgaatat cgctcatatg
     2941 gcggattgaa actaaaacac tacaatatat ttcttaaata gaccttctat aaaagctaga
     3001 tttaacctcg ataaaaatag atgcagtgct tctaaaatac tggaataggg catataggta
     3061 atcgtagaca agtgttttat agattgtctc gcaggagatg caagcatcac taaacatata
     3121 gagtatttgt attattataa tatcaacatg ctataaattc tatcatgcaa aagaatgact
     3181 agaacatgaa agacaggcac aaaattttga acaatattct gaaaacaaaa aaagacgcga
     3241 gtttccacaa tctcactcat ggaaactcac gtctttcaaa aaatagggtg aattgaaaac
     3301 tagaacaaga cactagattt tctaaatgat gtctagtaag gattctaaat gctacactaa
     3361 attgctcaca tcttatttca aaccacggga ctcccacaag aaaggaaaat cctataaaaa
     3421 ttctctctct gaggagaaag aggcctcaac tacaggtgta aactattatc aattgaaaac
     3481 aacagttttt acactcaatt agacttttta gggacaggat cactttcgct tgactgtagt
     3541 ttgtcatttt tttgataaag ttagcacttt ttcagaaact gttttgaaag tctcaatgat
     3601 atagtctact tcttcatcgc ttaatttagt atgaagaggg agggtaattt cattctcaaa
     3661 gaaggcatag gccttaggat agttcgtcat atcaaatcca agattcttat aggctgtcaa
     3721 gagaggaagc ggtttgtagt gaacattact tgcaattcct gctttagcca attcttggat
     3781 gatgaggttg cgttcttcta ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga
     3841 agattcgaca gtttcagtct tgtgtgccaa aggatggatg cgagaacctg caaaaccact
     3901 atcatagcgg tccacaatgt ccttacggcg ttgcaacaaa cttggatagc ggtccaattg
     3961 taccaaacca agtgaagcca tgatatcggt catgttgcac ttataggctg gtgtaacgat
     4021 atcgtattcc catgacccca attgcatctt ggcaagagca tccttagttt gcccgtgaag
     4081 ggaaaggatt tggaattcct tgtacatctc ttcgtcatca atcactggat tggctttcca
     4141 agtcgcactt ccaccttctg ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt
     4201 aaagtcagcg atagaaccag aaggttgtcc tttataagta gatcccaaag cgtgggcact
     4261 atcagagaca atgacaatac ggttaaaggc cttttgccac ttgcttgaag cggtaaagaa
     4321 gtcacgtttt ttctccacga cttggaacaa acggtcataa tcgcaaacaa tccctgcgag
     4381 ctctactggg ataatcacct tagttttctc agtgatagct tgctcaagca ggtcatagtc
     4441 catctcaaac gtatctgctt ggatatccac catgacaggg gttgctccca cgtgcgtaat
     4501 gacactacat gaagccgtat aggtcatggc tggaacgatg acttcatcac caggtcccac
     4561 ttccaaaacg cgtaaaatca actccagagc ggctgtcgca gagttgagac aaacagtctt
     4621 aggtgtctgt gtgtaaagag acaagcggcg ctccagttct tttgttttag gacctgttgt
     4681 gatccaacca gaacgcaggg tatccgctac ttcagcaatt tctgcttctg tgatatcagg
     4741 cggtgaaaat ggaatattgt aatttggcat tgatttgctc cttttatctg tactcatttt
     4801 cttatgacta ctttatttta gtacctcaaa cacggtttga aacatgattt tgatgtcccc
     4861 aaagaaacta aactctcgga gataggcgag gttatagcgc atcttttcag gaagaacatg
     4921 ctccacatag gcctgatcaa ctgacagacc tttctccgtc atttgactga tgatggtgtc
     4981 ctcatccttg tagttgatgc tggctggaga ggtaattcct gcttgcaaga gcaaggttgc
     5041 catcatttca gggctatact gctctgtata acgtggcact tcaggtcgtg taccgacaaa
     5101 ggacatctca cctttaagga cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg
     5161 gatgaaattt ccaaccttgg taatacggct atcgttagca gaagtcacca gacttccttt
     5221 tttatccgca tccgtcacca tggtacggaa cttccaaatc ttgaaccgac agttgtactg
     5281 ggtcacacgc tcttgcttgt aaatcactgg ccccttgcta tccaacttga tccaaatgct
     5341 caagatgaga aagatgggag aagttagaac cagtaagacc aaggccaaaa cccagtccaa
     5401 gcaacgcttg aaaatcagcg aacccttcct tttagagaca agctggtagt aagactcaac
     5461 ctcgcttgat ttcatttcca caggcaagtc ttcccatttc agcatgctgt tctcctttgt
     5521 ttttattata ctatttgtca acatttttca ttataccaca aaatggaaaa ggcggtgaaa
     5581 gaaatctgta atttgaagga tttccttcta gtactcaatg aaaatcaaag tacagctttg
     5641 agattgcaga taaagctgac atggtttaaa gagattttca aagagtatcg gccatggccc
     5701 ctgcctgcaa actatacatc ttgtgataag ttcctcccag agccaagagt tcctcatggg
     5761 ttccactctc gataatgcgt cccttatcca agacatagat gcagttggcg tcttgaatag
     5821 tagaaaggcg gtgagcgata gcaatagttg ttcggccctg tctcatcttc gccagagaag
     5881 cttgaaccaa gctttctgtt tcagagtcaa tattggctgt cgcttcatcc aaaatcagga
     5941 ctttaggctg gctggcgact gttctagcaa aggcaagaag ctggcgctgc ccagtagaga
     6001 agctcgaacc acgctcggaa acaggggagt cgtacccctg aggaagttct tgaataaagg
     6061 aatctgcatc cacaaaggct gccgcagcct gaacctgctc atcactgatt tcttggtaca
     6121 tggcaatatt ggacttaata gttccatgat agaggaaggg ttcctgcaag accaaaccga
     6181 tgttttttct cagctcttct tgactgaaat ccctgatatc cacatcatcc aagagaactc
     6241 tccctgactg gaattcataa aagcgcatga ggacattgat aatagacgat ttccctgaac
     6301 ctgtatgacc tacaaaggca atggtttcac ccttattaac agagaaagaa atgtcatcca
     6361 gaatcggatg tttaccgtca tatgagaaac acacatgttc aaaacggata ttgccttctt
     6421 ggactttggc ttgcccattt tcttgaagag gttcataggt cctctcgtct atcagggcaa
     6481 agacacgacc tgcagaaacc atagccgttt gcagagttga aaagttttgc gtcacctcaa
     6541 tcaaggggtc aaaaaggcgg ttgatgtact ggataaaggc atacatggtc ccgaccgtta
     6601 tcccgataga aaaaccacgg tagccaaagt aggccatcaa gactgcatag cctagaagtt
     6661 tcagcaaact catggcaggt ctcaaaaaga gggcatccaa ggctacagaa cggttggcgt
     6721 agaccaagtg ttcttggttg atttcatcaa attctgcctg caggcgcttc tcttgattaa
     6781 aagcctgaat aatcctgatt ccctcgatat tctctgccag cttactattg atatctgaca
     6841 agagacttct ggttttctcg atgattttca ctgacttttt tcgatagaga ttgaccaaaa
     6901 ggaaaatcaa aggaagaaag agcaagacta aagccgtcaa acgaaaatcc agcaccaaca
     6961 tggtataaag ggttgtcaga aagataaaaa ctgctgagat aaagctggat aaaatcccag
     7021 aaaacatatc actaatcgtc tcggtatcgt tggtcaaacg agaaacgata gaacctgctg
     7081 gcgtcttgtc aaagtaagac atgcccagtt tctccatatt ggcaaaggca tcccgacgaa
     7141 tatccctaac aatactgtaa gacacgcgcg caaagagaag attgcctaca tactgaacta
     7201 cagtttgtag gatgtagaga ccatagtaga ccagcaaaac ggtaacggct agttggttaa
     7261 gattgctgag atactggtcg ataaagtggg aagccacgag gggtatgaca cttttaatga
     7321 ccgtcgtcgc taggagaaaa ctgagtgcca aaaagatcag gagtccataa gacttgagat
     7381 aagacatcaa gcgcttcaat acagcccatt gttcttgttt attctgcatc ttcttctcct
     7441 ttcatttcta actgctgaga ctggtaggtt tgggcatacc agccatccat cgctagcaag
     7501 tcttcgtgcc tgcctcgttc gataatttga ccattttgta gaactaaaat aaaatctgca
     7561 tggacaacag cactgaggcg atgggcagtg ataatggttg tcttgtcctt tcgcgtctcc
     7621 ttgaggttgt cgataatcgc atactctgtc ttggcatcta cggcggataa ggaatcatcc
     7681 aaaatcaaga tatcagggtt taaaatcata gcccgactca tagccaaccg ttgcttttga
     7741 ccaccagaaa gactgactcc tttttcacca atcagcgtat caaatccttg aggcatgtct
     7801 acaatatctt ggtaaactcg ggctagctta gtagcttcct cgaccgctga aaggggcaag
     7861 ttaggattgc caaagcggat attgtctagg attgaagttg caaagagaaa ctggtcctga
     7921 ggaacatagc ccatgagact gcgaaggtct gtcagacgat agtcccgaat atcgtgaccg
     7981 tttagataaa tggcgccctt atccacatcg tattcacgca agagaagctt gattaaggac
     8041 gttttcccag agcctgtctg cccaaccaag cccagtgttt gcccttttgc caaactaaag
     8101 tgaatatccg tcagtgtttc ctcattttca aaagcaaagc tgtcaatggc atactccaaa
     8161 cgcccatttt caataccatc cagaggaaac tcagggtctt gtacaggaga ttcctgagac
     8221 aaaagatttt caatccgctg gtaagaaacc ttccctcgct gagtagtatt aaagaggaag
     8281 ccgatggcca taagaggcca gaccagcata tccaaatagc tgataaaggt gaccagattc
     8341 ccaactgtaa tctgcccttc ctgaaccatc aaggagccaa ccaaaagcgt taaaacatag
     8401 gacgaaccaa caaacaagag aaccataggg tcaaagagac tatcatattt catggtttgc
     8461 aggttctttt ggaaggttaa ttcattgact gcctgaaaag acttcaactc gtctgcctga
     8521 taaccgaaag acttggtcac tttgatacct gatacggact cctgtacctt gttattgagt
     8581 tcagaaaaag cagcttggga ttcgccaaag gccttatgag tctttctccc taggcgacta
     8641 gtcgcatagg ccatgaaagg tagggggaga atggcaacaa gagtcatctg ccatgagatg
     8701 ctaaagagca tggtcaacaa agtcaccaga gccgtgatag aggcatccac cgcagacatg
     8761 acaccgccac ctgctaaacg agtcaaggca ttgatatcat tggttgcgtg tgccatcaga
     8821 tcacccgtcc gataggtttg ataaaaggct gacgacattt ttgtgaaatg cttaaacaag
     8881 cgagaccgca tgatctgtcc caagcaataa gaggtcccaa ggatatacat acgccacaca
     8941 tagcgcaaat agtacatacc aaaggctgca agtagcaagt aaaataggct aagaaggagg
     9001 tcctgctggg ttaattgccc cgatgtgatg gcatcaatga cccgccccat aaccatagga
     9061 ggaatgagat tgaggacgga aaccaagatc agggccacaa ttccgactag ataacggcgt
     9121 ttttctaact tgaaaaacca ccaaagtttt tgaataatgg acataaaatc cctttctgat
     9181 tgcaaatgga aacctgaggc caatactcaa tgaaaatcaa agagcaaact aggaaactag
     9241 ccgcaggctg ctcaaagcac tgctttgagg ttgtagatag aactgacgaa gtcagtaacc
     9301 tacatacggc aaggcgacgt tgacgcggtt tgaagagatt ttcgaagagt acaagacccc
     9361 aggtttttct tattcataag ttacgactgt aacagcaccc ttgtcatatt cagcaataaa
     9421 gatattggct acattgtcat gcccttgttt actgaggtta tcaagcaacc actcttcgct
     9481 acgaccaatc gattccaaga catctacttg aatcacaccg tcagtcacaa ctggatactt
     9541 aggattttca tctcccattt gcacaacgat gagttgccca ttttgctctt gcacagctcg
     9601 tttgacttgc ttcatctgga aaatcccttg gctacgaagt ttgagggata catccgatgc
     9661 agacaaacca actgaacgac aggcttctgg gtcaatattc ccatttttga taaggagagt
     9721 tggcttacca tcaatcaaac gtttcacaaa gtgaacattg ttgttgagct atttgagagt
     9781 caagatcagt ttgattaaaa tttcgatata attaagtgtc atttgttcac atccaccagt
     9841 tcaattgcgt ctgtcttata caattcgact ttctctaaca ggtacttgtc tggctcactt
     9901 ccgtttaggg cacgataata gcgatctccc accttgataa gtgcgccatc tgtgtttgtg
     9961 gaagtattaa catagacttc tgacttgtct actcccaaat ctttggaaac aacctcgatg
    10021 aaatgaagtg aagtttgaaa tttattgtta gaaacttgat tgttttgata agtcgtgatg
    10081 ctgaccaaaa gcatagctaa ataaggccag agctgaaatt atgaccaact cacgaaattt
    10141 ggttcctttt ttatcatggt atgccttgaa agcaaaaaaa actgtcacag ctaataaaac
    10201 aatcccaaag ccaaccatga taccattttg ctgaccgatt tggctgagta catagtcata
    10261 agagtagaat ttcatgtatt ttcactccct ttcataaaat cattcttaat tataaacgaa
    10321 agagagtaat ttttcaaacc atacgttggg gaaatagatc tttttttggt ataataaaat
    10381 ctataatctg aatgaaaaag gtaactttat gaaacttatc tcatggaata ttgattccct
    10441 aaacgctgcc ctaactagtg actcagctcg tgccaaattg tcccaagaag tcctacaaac
    10501 cttggtcgct gaaaatgctg atatcattgc tatccaagaa accaagcttt ctgccaaagg
    10561 acctacaaag aaacacgtgg aaattttaga agaactcttc ccaggctacg aaaacacatg
    10621 gcgctcttcc caagagcctg cccgtaaagg ctatgctgga accatgttcc tttataagaa
    10681 agaacttacg cctacgatca gttttccaga aatcggtgcc ccttctacca tggacttgga
    10741 aggccgtatc atcactctag aatttgatgc atttttcgta acccaagttt acactccaaa
    10801 cgctggtgac ggtctcaaac gcttggaaga acgccaagtc tgggatgtca aatatgcgga
    10861 gtatttggct gaactagaca aagaaaaacc agtccttgcg accggtgact acaacgtagc
    10921 ccacaatgaa atcgaccttg caaatcctgc tagcaaccgc cgttcacctg gatttactga
    10981 cgaggaacgt gctggattta ccaacctttt ggcaactgga tttacagaca ccttccgcca
    11041 tgttcatggc gatgttcctg aacgctacac ttggtgggca caacgcagca aaacttctaa
    11101 aatcaacaat acaggctgga gaatcgacta ctggctcaca agtaaccgta tcgctgacaa
    11161 ggtcactaaa tctgatatga ttgactcagg tgctcgccaa gaccatacac cgattgtctt
    11221 ggaaattgac ttgtaaggat tttctatatg gactacaatg cggtcattcc cgagtttctt
    11281 gtatcgaata tcgaacagtc ccggtccttc tactgtggtt tactgggttt taggattgaa
    11341 tactaacgtc cagaagaaaa ctttctcttt ctcttgaaga gtgtcaacta atgttagagg
    11401 agggaacaaa ggatcaacta gctgaactga cctacccctt tggtcgtgga gtcaatctct
    11461 cctttggcat aaaggatgtt ccaaaactct atcaaaaagt gatggaggca aactatccta
    11521 tttatcgtct cttgaccaaa agaaagtttc gtgtcagtga tccctatatc tatcctcata
    11581 aatttgcagt tttggatcca gatggctatt ttttaagatt tagcgagtag aataataaaa
    11641 attgggaaaa gtctttaaag ttagaaaaag gcatattgtc aggtgtctaa aaacttgata
    11701 gtatgccttt tatgatggaa aaatcttcta atactcttcg aaaatctctt caagccacgt
    11761 caacgtcgcc ttaccgtagg tatatgatac tgactctgtc aattctatcc acaacctcaa
    11821 aacagtgttt tgaggttgtg gatagcttcc tagtttgctc tttgattttc atttagtata
    11881 aatgttagct tacaatggag tttttgttca ccctctcttc tttttgttcg ctttttaaac
    11941 cgaaacacta acaaaatagt tgatttataa agttatttag tgtaaaataa aaacattggc
    12001 tcaagcctat ttaaaattga atatcgtttt acttgtttat gtcgtgaatt ggcacgacgt
    12061 ttctacaagg tgccggaaca cctaacaata agtaagtcag cagtgagata tggccgtttt
    12121 tgccatgtct atttagggga cttacttaga gattaagtag gtcttttttg aatattttta
    12181 atatttccct taattagtgc ggacgggagg tgaaattatc ctgtgaataa tttcaggaat
    12241 ccagggaatt tcatccctaa tttttgagcc cctagctctt tcatttctag gcttaggcta
    12301 aaatagttcc ccgaactatt ttactctcaa aaatcccgtc atagacaata acaagattat
    12361 tgtctatgat accactacaa cgggaaatat ttgataagac tcgcttcgct cgtaatagtt
    12421 ttatcaaata tatagtatta gcaaaaggga tcactataga aatatttaaa caacaagtaa
    12481 attaactttt agactttagg aggtcttatg aaattattag aagagcgcat cctcaaggat
    12541 gggcatatct tggatgataa catcctcaag gtagattcct ttttaaccca ccaagttgac
    12601 tttagcttga tgcgagagat tggtaaggtt tttgcggaaa aatttgctgc tgccggcatt
    12661 accaaggtcg taaccattga agcgtcgggt attgccccag ccgtttttac agctgaagcc
    12721 ttaaacgttc ccatgatttt cgccaaaaaa gctaagaaca tcaccatgaa cgaaggcatc
    12781 ttaactgctc aagtctactc ctttaccaag caggtgacca gcactgtttc tatcgctgga
    12841 aaattcctct caccagagga caaggttttg attatcgacg atttccttgc taatggccaa
    12901 gctgctaaag gcttgattca aatcatcgaa caggccggtg ccacagtcca agctatcggt
    12961 atcgtgattg agaaatcctt ccaagatggt cgtgatttgc ttgaaaaagc aggctaccct
    13021 gtcctatcac ttgctcgctt ggatcgtttt gaaaatggtc aggtcttatt taaggaggca
    13081 gatctctaat gcaaactcaa gaaaaacact cgcaagcagc cgttctgggc ttgcagcact
    13141 tactagccat gtactcagga tctatcctgg ttcccatcat gattgcgaca gcccttggct
    13201 attcagctga gcagttgacc tacctgattt ctacagatat cttcatgtgt ggggtggcaa
    13261 ccttcctcca actccaactc aacaaatact ttgggattgg actcccagtc gttcttggag
    13321 ttgcattcca gtcggtcgct cccttgatta tgattgggca aagccatggt agtggcgcta
    13381 tgtttggtgc ccttatcgca tctgggattt acgtggttct tgtttcaggc atcttctcaa
    13441 aagtagccaa tcttttccca tctatcgtaa caggatctgt tattaccacg attggtttaa
    13501 ccttgatccc tgtcgctatt ggaaatatgg gaaataacgt tccagagcca actggtcaaa
    13561 gtctcttgct ttcagctatt actgttctga ttatcctctt gatcaacatc tttaccaaag
    13621 gatttatcaa gtctatctct attttgattg gtctggttgt tggaactgcc attgctgcta
    13681 ctatgggctt ggtggacttc tctcctgttg cggtagctcc acttgtccat gtcccaactc
    13741 cactctactt tgggatgcca acctttgaaa tctcatctat tgtcatgatg tgtatcatcg
    13801 caacggtgtc tatggttgag tcaactggtg tttatctagc cttgtctgat atcacaaaag
    13861 atccaatcga cagcacgcgc cttcgcaacg gttaccgcgc agaaggtttg gccgtacttc
    13921 tcggaggaat ctttaacacc ttcccttaca ccggattttc acaaaacgtt ggtttggtta
    13981 aattgtcagg catcaaaaaa cgcctgccaa tctactacgc agctggtttc ctggttctcc
    14041 ttggactgct tcctaagttt ggtgcccttg cccaaatcat tccaagctcc gtcctcggcg
    14101 gtgccatgct ggtgatgttt ggttttgtat ctattcaagg gatgcaaatc ctagcccgag
    14161 ttgactttgc taacaatgaa cacaacttcc ttatcgcagc tgtttcaatc gctgcaggtg
    14221 tcggtctcaa caacagtaat ctctttgtca gcatgccgac agccttccaa atgttcttct
    14281 caaacggaat cttcgtagcc agcctactcg ctattgtcct caatgccgta ttaaatcata
    14341 aaaagaaata agaaaaagag gtgcgagcct cttttttgtg tgacaaaata aaaacatcta
    14401 cctattcata tatgctagtg tcatagtcct gaaaatcatc tgcatcaaga acaatttcac
    14461 aactcttata cttttctctt acaagtcgtt cggcttcatc tggattttca gcctctatac
    14521 ttactaaacg tgataaagtt tctgtaattt ctactgtata ctttttcagt tttagattgc
    14581 tttccaataa ttcacctatt aacaataatc tatgatagga gctatgtagc cactctggca
    14641 atttatctcc tacttcccac ccatattttt ccttcatcaa agctagttgt ttttcgtcac
    14701 caaatttcat attttcagat aaccatctca cacaatcggg atctgataag gtacagacga
    14761 ttaaacttag gttatcgtaa cggctttcag tttcataatc aggccagatg acttttaaga
    14821 aatcatacac ctcttctgat gcaacaagtt gtttcgtttt cataatttcc gatactttcc
    14881 tctaccttta aattctatta tttctttgtc tcttaatatt tgaagctgtt gcctaatctt
    14941 ttctttgata tgattgttct taacaaagat attttttagg tcactttcaa aacgatacat
    15001 atcttcaagg gtaaattctg aaccctctat cttatctata caatttagaa tttctattgt
    15061 ccaacctctt gatgacagag agctcttcct taaaaataaa ccttgcttaa attcttttgt
    15121 aactttttct ggatctctaa cttgtccatc ttgcacaaga aatatccttc ctttagaagg
    15181 tacttgtgat aaatcaatgt tacaaccaat ccaacctgct cgtctagcag ttggtgcaag
    15241 tggttttctt tgaataattg atttcggtgt aacaaattgc ttcggaagga caagaaagtt
    15301 atttacctca aaattttttg tgtaagttaa aaaaaagaaa ttaggattat tatctgcctg
    15361 cacacgcttc atcatcgttg cataagcacc atcattgatt gttgatgaaa aatttccttt
    15421 tttgctcttt agttcaaact cctcactaca atgattacag taaaaatctg ctacaggccg
    15481 attattttca aaatgattta agggattgtt cccacaatta gggcaataag actgacgata
    15541 aacccaatcc tccgttaaga tacgtgcctt ttggctatta cttttatagg tttctactaa
    15601 ttctaaatta aagtgtaatt ccatttaaaa attcctcact aatatgagaa ctcactcgat
    15661 ataagcaatt aaaatctact ataactagta taccacatat atgtacctat tacatttgta
    15721 tttcaccact ctcttttata tttccttcta acatatctca taaattaaaa atgagtgaga
    15781 taaatttatc ccactcacct ttctttatat ccttacccgt ctttcctcag acctttggcc
    15841 tgtgacaaac atggtaaagg ttgctttaca gacatttctg ccctcttgat tggtgatatc
    15901 cacatccatc acacaggttg tacgaccttg atggacacat tctcctttaa tggtcaatac
    15961 atcgtcgagt tttcctgcct taaggtagtt gatagaggat tggagtgtca ccccatcaag
    16021 tcccagcgag ataaccacca aaccactgat ttggtcacat agcgtgaata gatagccacc
    16081 atgggcattg ccatagtagt tgagcgacga gttcactact ttggtcgtca ccacaacgtg
    16141 accatctctc attttttcaa tttcgtaatt ttcaaaggca gatatagcgt caaaatgaaa
    16201 gtctttcatc gtttcctcct gatatttcaa acgacactat gatactactt tttataggac
    16261 tgtgcaagga gaaagctcct agtctagtga aattccgacc tgttccacaa agcgcataaa
    16321 ggctgtctgc ccttgttctg tctgcttgta gactcctgca tcctcaagta cacgcacaaa
    16381 gatagcaccc acagagtcct tgacgattgc aagggctttt tctttatccg ttaggtctgg
    16441 atgttgggat ttgagttggt ctgcccactc ctgatgataa tcggcaactg taacagcttc
    16501 tcctacaaga tagctagcga cttgctccac ttcttctttc agacgtggtg gcaagattgc
    16561 caagcccatg acctcaatca agccgatatt ttccttcttg atatgttgga catccttgtg
    16621 gggatgatag atgccatcag gatgctctgc tgaagtctga ttgtctcgca agaccaagtc
    16681 caactcaaac tgtccatcac gcttacgcgc tattggtgtg atggtgtgat gcggcgtccc
    16741 gtctgtctct gctaaaatct gcacactaga atctgaatac tgacgccatt cctggaaaat
    16801 cttatcagct aagttaatca aatcctcttt ggaatccgaa gtcaagcgta ggacagacat
    16861 tggccacttg ataattccag ccttgacctg ctcaaaacca gcaaatcgga aggtcttttg
    16921 caagggagcc aattccatag gaaatacgtg acggcctccc tgataatgat cgtgagttag
    16981 aatagagccc cccacaatcg gcaggtcggc attagatcca gcaaaatatc ctggaaactg
    17041 ctctacgata gccaacagac gttcaaaact ctgacgacta atggccatgg gacgatgctg
    17101 gccatctaaa aagatacaat gctcattaaa gtaagcatag ggcgaatact ggaaccccca
    17161 ttcctgacca accatttcaa aacggataat ccggtggttg ctgcgagctg ggtggttgac
    17221 ccgaccatgg taaccctcat tctctaaaca aagttgacac tgaggataat tactagcttg
    17281 caccaacttg gctaccgcaa tctctttcgg atccttttca ggcttagaga gattgatggt
    17341 aatttcaagt tctccataat cagatggaac acgataagcg atatttttag caatggcctt
    17401 gagtttgatg tagtcatttt tctgactgag ttgataaaaa tcctctatcg cttgctcagg
    17461 agagtaggca taggcttccc agaagtcacg attgacctga ctcggacaag gagtcaccaa
    17521 gtccatcagt tcagtaccaa ggatttcacg cgcagtctga ctatcctcaa tcgtctctaa
    17581 tcgaacggct tcctcaacta gctgggcctt gaggtcaatc aatttatcca gattggtctc
    17641 aacttccaaa acaccttctc ccactcgtgc caaaacacga ttggtcaggt agattcgatc
    17701 catttcctca aatgaacttt cagaaatgac atgtgttaca aatttatcta ctaaggtcac
    17761 tatagagcct ccttttgact agtcaaggac gcgagtgcca cctgcaactt cagcgatata
    17821 gaagcttgga gcgtatccaa ctacttcctc gtagtgtttg cctacagctt ccttaaaggc
    17881 ctcaacagta tctttttgaa ccaaggcaat ggcacagcca ccaaaaccag cccctgtcat
    17941 acgagcaccg agaactcctt cttgtgccca agctgtgtga acaagggtat ctaattccaa
    18001 accagttact tcataatcat gctccagaga aacgtgtgac gcattcatca aacgaccaaa
    18061 tgtttccaaa tcacctgctt gaagggctgc ttgagcttta agggtacgtt ggttttcaag
    18121 cacagcatgg cgagcacgtt tcaaacgatt ttcatcttta attagatagc tatattggtc
    18181 aacggcccac tcgtccaatt cacccagggt ctgaatatcc aaggcaactt gcaattcttc
    18241 cactgctttt tcacactcag cacgacgttc attgtattta gagtccgcca attcacggcg
    18301 tttgttggtg ttcatgataa caacgacatt gtccttcaaa tcaagtggca ccaaatcata
    18361 ctctaaggtg ttggtatcaa ggtaaatagc acgttgatca gcccccatac caatagcaaa
    18421 ctggtccatg ataccagagt tgactccgat aaagttgttt tctgtttgtt tgccgatttt
    18481 aaccaaatcg agacgctcta attttaaatc aaagagatgc tctgccacga ctcctgtcaa
    18541 gagctccaag gatgctgaag aagacaagcc agcaccattt gggatattcc cataaacata
    18601 aaaatcaaaa cctttgtcaa tcacgtgccc agcttcttgc aagaaatgaa gaaccccttt
    18661 tggataattg gtccagttgt gctctttttc aaacttgagg tcagcgagag gcacttcgat
    18721 aatgcccttg tcctcaaagt tagctgagta gaaacgcaag acttggtcgt cacgcttacg
    18781 agctgcaccg taagttccca aggaaatagc agcaggaaaa acgtgcccac cgttgtagtc
    18841 tgtgtgttca ccaatcaaat taatacgacc tggtgaaaag aaggtttggt ctgcttcttg
    18901 accaaaaaca gcaagaaagt ctttgcgaag gacttcagta gtaagatgtt gtgccatatg
    18961 aattctcctt tgactgtccg ttaagccatc ttaacgtgta atcgttttct tctattgtat
    19021 ccaaggaatt tcccaaggtc aatccttttt actaaaattt tagtaaaaca tcagtaaaaa
    19081 gaagaaaaat atgatatact aacctaatca aggaggattt atggctacct taaaagacat
    19141 tgcacagcta gcctctgtct ctatcgcgac cgtatcccgt gtcctcaacc gcgaccagag
    19201 cctatctgtt acagaagaaa ccagacaccg tattttaacc gttgctgaag agctgggcta
    19261 caccaagcac ctcaagacag gcgagtccca taaacccaag caaaagattg ccattattca
    19321 atgggtcagc gaacaagggg agctagacga cctctactac taccagattc gcctaggaat
    19381 agaaaaaaga gcccaagagt tggactacga tatcttgcgc tattttaatg accatccttt
    19441 taccctaagc gaggaagtga ttgggattct ctgcatcgga aaatttagcc gagctcagat
    19501 ttctgccttt gaagaatacc aaaagcctct tgtatttcta gacagcgata cactttccct
    19561 gggacatacc tgtattatca cggattttta cactgctatg aaacaggttg tcgattattt
    19621 cctcagtcaa gggatggacc gcatcgggat tctaacaggg cttgaggaaa caacagacca
    19681 agaagaaatc attcaggaca agcgtctaga aaacttcaaa aactacagtc aagcgagggg
    19741 aatctatcat gatgaactgg tctttcaagg aagatttact gcccagtctg gctatgactt
    19801 aatgaaggag gccattcaga gcttgggaga ccaacttccg ccagcatttt tcgcagccag
    19861 cgatagttta gctatcggtg ccctccgtgc cctccaagaa gctggaatca gcctgccaga
    19921 tcgcgtcagc ctcatttcat tcaacgacac cagtctgacc aaacaggtct atcctcccct
    19981 ctctagtatt acagtttata ctgaagaaat ggggcgagca ggtatggata ttcttaacaa
    20041 ggaagtcctc cacggtcgca aaattcctag cctgaccatg ctgggaacca gactgacatt
    20101 aagagaaagt accctaaatc aagaatagga taacataaaa aacgaataga gttctaaaac
    20161 tcctattcgt tttttattcg attacaatca tagacttaat tgtcttacgt tcatccatat
    20221 ctttataggc ttggtcgata tcttccagtt tataacttga agtaaagacg cgacctggat
    20281 tgatatcacc atcaaggacg gcttttagta aaaattgctt atcgtatgtt gtagcagaag
    20341 ctgccccacc tgctacagag atattttgca taaatgtcga accaagagca cgattattat
    20401 agtgtgggac tcctacaaag cccatacgcc ctccattatg aagaacacct agcgcctgtt
    20461 ctatagcagc ctccgtacca acacattcaa gtgctgcgtc tgctcctccg ccgaggattt
    20521 cacgcacctt ggtaattcct tcttgaccac gttctgcaac aacagctgtc gcacctgact
    20581 ccatagccat cttttgacgg tcttcatgac ggctcataag gataatttgt gatgctccac
    20641 gcatcttagc cgcgatgaca gcacattgac caacagcccc atcaccgata acaacaacct
    20701 tgtccccttt ttgaacattt gcaacacgcg ctgcatgata gcctgtcggc atgacatctg
    20761 caagagtcaa aagggacttg agcatccctt ctgtataatc agaaggttga ccagggattt
    20821 taaccagcgc ccagtttgca tagtggaagc gaatatattc tgcctgaaaa tcacccccca
    20881 aattattacc aatatgattg tcgcaagaac cgtcaaatcc agcaagacag gcatcacact
    20941 caccacatcc atgtgtaaaa gggacaatca caaaatcacc tggtttcacc gtcgtaatgg
    21001 cttccccagc ttcttcaaca atcccaatcg cttcgtgtcc actattttta tgtccagctt
    21061 tcgtttctgg attacggtac ctccataaat ctgaaccaca aacgcacgca cgaaccacac
    21121 gaataatcac atcatccgct tctattattt gcggacgttc aatgctagca agtccaacct
    21181 gacctgcctt tgtatatact gctgatttca tttaaaattt tccttcctta taaagtttaa
    21241 ttttgagatt taaacgattt aaagctgtct gtagctgaga caagcgctcc tctaattttt
    21301 gcttttcctc ttctaaaata ccaagcctct cctctctcgt ttcatctccc ttttggtaga
    21361 gcgacatata gtcaactaaa ctatctacag agacacccgc cgaacgaaaa cacttaataa
    21421 attccagcgc ttcgatatcc tgatcttgaa aatcacgaat cccagtagca gtacgagtaa
    21481 tcggtggcac aagaccaacc cgttcataat accgaatcgt atccgctgaa attcccaaca
    21541 aatcactggc agatttaata ttcacacgct aacctcctct catttcattc actgaattca
    21601 cgctattcta actcacttat cttattatat aactttgagt tgactccaag tcaagcattt
    21661 tgtatctaat cgaaaaattt ttatcattaa caatcatata tctggagttt atacaatgct
    21721 cttctcttac caatttttga aatatttaaa taataaagaa attactctat tccaaataag
    21781 atagtaccca agtatttttc acttttttct aatgttgatg ctcataactc cgttccaagt
    21841 cacacacctt tcgcttatgg gtttggtgag tttctaggtc agcatcaatt tcaatggtaa
    21901 tattttgaaa accacaatct tttaggaaaa ttcgaataga ctctttacaa gtttccatat
    21961 gttccatttc ttttagacaa acatgtacaa tggcattttt ttccaaagca tccatagtcc
    22021 agagattaag ctgattaagg ctggccacat tgtccaatcg ctccaggcca ctctttactt
    22081 gcttgatatc aagaccttct ggcacagcat ccaagaaaat cttgagtgta gaccaaaaac
    22141 gtggaagggc ttttgaaaga ataaagaaag aaatgacaag ggacaaaaga ggatctagga
    22201 tataccagtc cgtaaatcga agaacaatcg ccatcaggat aacagctacc caccctagcg
    22261 tatcttccag aaaatgcaaa ctcagaatag actcattctt tgtctttccc ttaccaacca
    22321 ccagactcgc taacagattg atagtaatcg caataattcc taaccagaga atcccctcat
    22381 cattgactgg ttgcggatgc aaaatcttcg tgacattttc caaaatgact agaacagagc
    22441 ccgttacgag aatcacagct gttaccaagg ctcctagcag gctaaaccgc ttatagccca
    22501 aggtgtactg attgtcttct tcacgattgg agattgtttc tagaaaagct gatattccaa
    22561 ttgcaatcgc atctcccaag tcatgcacag agtcagcaag aacagcgcta gaaccaaata
    22621 ctccacctgc aataaactca acaatggcat aagtcaaatt taagaaaaaa gccacccaaa
    22681 cagcatattt tgccttcata tttctcattc ctttgttata atagatttat gaacaccttg
    22741 ttcattatca ttatccacta aaactcaaag aaaggataga agcaaaacgt cagctttatt
    22801 cagttctgaa caatttgcct taagtgtcca tatgactaac attgaccgcc gtatcagcaa
    22861 aaccaaaaaa gccatctatc aagcttttat acaacttttg aatgctaagg gctacgaggc
    22921 cactactgtt caggatatca ttgatctcgc agatgtggga agatccacct tttactgtca
    22981 ctatgaaagt aaggagcttc ttctggacca gctctgccgc tacctcttcc atcatctttt
    23041 tgaaagagag caagccattt caaccgagga ctacctcgcc cacctctttc tccattttca
    23101 taaaaaccaa gaccatatca ccagtctgct attttccaaa aatgactact tcctccgtca
    23161 actccataaa gagctagaac accatgtcta ttccgtgcta gctgataatt taaaagaagc
    23221 ccaccctaat atgcctactt cttacctcca acacttggtc gtgtccaact ttatcgagac
    23281 attgacctgg tggctcaaaa aaggtcaaga tttcacaggc caggaagttg tccaatttta
    23341 tctagacctt ctcattccta aaaattgaat atagagtaaa gctcagttgt cttatttcta
    23401 ggttactgag ttttttatct tttcaacaac aaaagaggac ccgccgatcc tctttttcat
    23461 actataaatc cttgattatc aactatatct gttttaatcg aaatctcaaa acagcacttt
    23521 caaacatctt ttcctagtta agtaaatcag tattctgctt agctgccttg ctccattgat
    23581 accaaccaac tagactgtta atgagataaa ttagatattt cccttgaatt tgcaggcttt
    23641 ctccccacca gagatagatt gaaaaaacat tggtagccgc ccagaatatc cactgttcac
    23701 ggtaaacagc tgtcatgagg atttgcccta ccccattggt tgcatctgtg attgaatcac
    23761 gatagggacg attggcacca atagactgat aaatgaagcc aaaggccaac caccaaagca
    23821 cactaatgga aagatacttt gtccagccct tgccgtccag tttacgcgcg acaaactcct
    23881 gcttttcctt cttaaactgt gcctgataaa tccaaactag aagtccaatt ggctgcatga
    23941 ctgtgaagta aagtgtcgtc agcacctcac cataaaagcc tttctgtagg gccaaaataa
    24001 ggtaaataac agagttaatc aagccaaaaa gataattact tgctcgacct tccgatacaa
    24061 agattacaca gataatccct gtcaagctac aaatcatccc aatccagtca acaatacgat
    24121 gttcgtaaac caactccagc cagagaggaa aacttcctaa aaccagcaaa taaatccact
    24181 gggcaaaact acgatgggca aagaggtcat cccagatagc cttcatagtt cctgaaaatc
    24241 ctaaatcagc catagccgca accatacgac ggtaaccacc tgacatttca cctagggttg
    24301 ttttgatatt ttcaattttc ttttgcaaat aagtatgcat catttctcct tttgttttta
    24361 aagagccgtg tctggataga ctttcggacg caacgctcta ttagataatg aactgcctat
    24421 acacaagatt tctaacctta gtcgacatga gctaaaacct cttatttgtt aagtagttca
    24481 caaaatatta tacacctatt ttatgaatag tcaactgtct ttacagtaaa attttagaaa
    24541 atcatgaaaa ttttctcttt ctttccattt taagtgacat tcagtcattc tcacatcaaa
    24601 aaagcccaga cgaaattgtc tgagcattct tttatctagt cgtttaagga agttgagttc
    24661 agtatgttta aagtctctgt cccatcattt cttcaacaaa ccttgttctt ggagaaactc
    24721 cttggctact tgctttgctg acttgccttc aacaccgact tggtagttga gctggctcat
    24781 ctggctttct gtaatcttac cagccaatgt attaagaact ctttccaact ctgggtgttt
    24841 cttgagaaga gcttctttca tgagtggagc cccttgataa ggtgggaaga gttgcttgtc
    24901 atcttccaag acctgtaaat cataacgctc caattccgca tcagtcgaat aggcatccgt
    24961 gatttgaata tcccctgact gaattgcctg ataacgaaga gctggctgca tagtcgccac
    25021 attgagattg agaccataca ttgattgcaa gcccttattt ccatcttcac ggtcgttaaa
    25081 ctcaagcgta aagcctgcct tcagctgccc ttccactttt ttcaaatccg aaatggtctt
    25141 caagccatat tcttgagcaa tctttttcgg aacagctaca gcataggtat tttgataaga
    25201 cataggtttg agataggcta gatgatcctg cttggcaatg ccatcacgcg ccacttgata
    25261 aacctgctct ggctcatgac tcaccttggg tgatggttga agcaaacttt cagtcaccgt
    25321 accggtaaat tcaggataaa tgtcaatatc accttttttc agagcttcat aaaggaaact
    25381 tgtcgtccca aaattcggtt taacagtcgc agtcatgctg gtattttctt caatcagcaa
    25441 cttatacata ttagccaaaa tttctggttc tgggcctatt ttcccagcaa taatcaagtt
    25501 ttccttctct ttttgagcca aaagagctgg actataagac agacccagta ataaagccac
    25561 caaggcaaaa ccagagaaaa tcgtccgcaa tttcgctttt tccattactt ttagtaggaa
    25621 gttaaaggca atagctagca ctgcagaaga aagggcccca atcaaaatca aactggcatt
    25681 attacggtca attcccaaca ggataaagga acccagtccc cctgccccaa tcaaggtcgc
    25741 caaggtagcc gtaccgataa tcaagaccgc tgccgtccga attccagaca tgataacagg
    25801 catggcaagt ggaatttcaa acttcttgag acgctcccat ctggtcatcc caaaggcaat
    25861 cccagcctct tgaagactcg gatcaattcc cttcagccca gtaatagtat tttgtaaaat
    25921 cggaaaaatc gcataaatca ctagagctgt caaagccggc aaggtcccaa ttcccatcaa
    25981 agggataaag agccccaaca aggccagaga cgggatggtc tggaaaatac ctgcaatctg
    26041 caagacccag tcggccagct tctcatgata gcgaagaaaa acagccaagg gaatcgcaag
    26101 caaaatagct agtaacaagg tcaaaagtga caactgcaaa tgttgagata gagctgtcaa
    26161 ccaatcacta aaacgatcct gaaaagttgc aattaaatta gtcatgaaca ctacctccaa
    26221 acaagtctgc tacaaagtct gttgcaggca cttttaaaat tgtctcggga ttcgctacct
    26281 ggcgaatttc tccatcctgc aagacagcaa tacggtccgc caacttcaag gcttcatccg
    26341 tatcatgggt tacaaaaatc gttgtcatcc caaactcttt atgcaattct tttgtcagaa
    26401 cctgcaactg ttttctcgaa atagcatcca aggccgaaaa gggttcatcc atgaggaaaa
    26461 tcttgggctg accaatcata gctcggacaa taccgacccg ttgctgttct ccaccagata
    26521 attcactagg taagcgatgc ccatactcgg ctactggtaa accaacctta gccaaaagct
    26581 cttctgtttt cttcgtaatt tcttccttgc tccacccctt catttcagga atgagagcaa
    26641 tattttccgc aactgttaga tttggaaaaa gagcaatagc ctgtaaaaca taaccagtag
    26701 aaagacgaag ttcacgctca tcatagtctt tgatgcgctt cccatccata taaatatttc
    26761 catcagttgg ttccaaaaga cggttaatca tcttgagcat ggtcgtctta cctgacccag
    26821 aaggccctac taaaaccata aattccccat cctcaatctg taagttgaca tctctcaaga
    26881 catccttttc tgtgtagcgc agtgctacat ttttgtattc aatcattctt tgtcctcaat
    26941 ttaaaacttc cctcgattag tcaagtcttc taccttaggc atgacttcct tattatccca
    27001 atgctccaca attttcccgt tctctaaacg gaagatatcg tactgggcat aagcaacgcc
    27061 atcaatctga gtctgaccat agctaaccac atagtttcct tgtcctaaga gttggaaaac
    27121 aaagtcaaaa gtgacactat attcagccac atagttttta taagcagcac ttccttgtcc
    27181 aatctcatga ttatgctgaa tcaaatcgtc tgccacataa tcactccact gctctagctc
    27241 cccattttgg aaagtttctg tcaagaaacg gcgaaccagc tttttatttt ctgctttctt
    27301 gtccaaatcc ttgatttcaa aatctccaaa aatttgatct agttggtcat tttcaggtgt
    27361 tcgatagtag tcaatgacat cccaatgctc aacaatacga ccattctcat ccgcacggaa
    27421 agtatccgtc gtcacccatt gagcttctcc accattcaga tattgatgaa catgaacaaa
    27481 gaccagattg ccatcctcaa tggtgcggac aatcttaatc tgacgctctg gatgacgctc
    27541 aaagaaatct gcaaagaagg ctgcaaatcc ttctttcccg tcaggaacac ctgtcgaatg
    27601 ttggatatag gtatccccta cagactgggc ttgagcctca gcaactcgtc cgtcttgaat
    27661 ggcatggatg tataggttgt gagcattttt cacttgttgt gacatattct aaacctcatt
    27721 ttccttctct ttcagatttg ccaaaattct ttcttgaaaa ccttcaaatt ggtgaatttc
    27781 ttcctctgaa aatcctttgt aaaagatagt atccaatttc tgactgacac gatgccccac
    27841 ttctttctgg aacttgccta actccgttaa aactaaatac ttcttacgct tgtcttttcc
    27901 acacggacta acaattacaa gcttttgttc ctctagcttt tttatcatag tcgtcagcgt
    27961 attattcgca agcccagtcg caagcgcgat atctgtcgca gttgcgcagc cagtttcact
    28021 attccataaa accgctaaaa tcttgccctg ttcaccccta taaagagcct caggatcttg
    28081 actcagtaac ttttgaaaaa tccgcccatt caacaaacga atatgatggg ctagcaaatg
    28141 actatctttc ataacacctc caatttattt cgatatcgaa atgaataaaa taattgtaac
    28201 actcatcgtt ctaactgtca actatttcga tttggaaata atttttgata attattcaca
    28261 ccaccatact ccggctcaac taacttttaa cgagagtttc taaattcctt cgtcctccag
    28321 tctacaaaag ccttccatcc gtactatcct attttttatg aggggacaca tttttcctat
    28381 cagatcattt attttaaaga tagaagtaaa tcataattgc ttccatctgt tcttttatag
    28441 tatattgaag ttggactagg gcactgtatc ttctaaaaca ttgatagaaa gcgatttgaa
    28501 tttcccaatc aatttgttcg tatttatagc attttgaaac tagaatagga cgccatgact
    28561 gctaaaagat ttctataaat tcatttgatt tccctaatca atttgttcat atcttatttc
    28621 attccgctat aatttcacct taccctatct ttttcgtagc acccttcaaa cagcctatcc
    28681 cctaccgttt gatgattcct cacttcactc cacttccatt acagaagttt cttcactact
    28741 atggtctcgg ctgacttctc atgattcctt gttactacta tttgaacgct cacgagatag
    28801 gtcttataaa aaatgctttg atccacaatg gaatcaaagc attttaaaaa gttcctcata
    28861 cataagcgca gaagtcgcag ttcctctgta cttggcttct tctcttttga caaagcgagc
    28921 caagttgagc aactcaggtg ctggatgttt gggatttagg agcaattcac gattgaccag
    28981 gcttgagaga cgaactgcct gcaattgctc atttgtagta ggcagttttt tagtagtctc
    29041 taggagagca gcaactaaat cttcactcaa atcatgtcga gcatgattgt aaagatcttt
    29101 tataaggctt tctaggtttg gttctaccat ccctaccacc tcccttatgg tttaataatg
    29161 tttaatcaaa tcaaccgttg aacgatccaa tttcttcacc aaggcttgta agaaagcttg
    29221 cgcttctagg aagtcatcca ttgcatagag ggtttggtga gaatggatat aacgagcgca
    29281 gacaccgata gttgttgatg ggacaccacc atttttcaga tgagctgcac ctgcatctgt
    29341 tccgccttta ccacagtagt attggtactt gataccagct tcttcagccg ttgtcaaaag
    29401 gaaatccttc atccctggga gaagcaagtg acctggatca tagaaacgaa tcaaggttcc
    29461 atctccaatc ttgccttgac caccgtagac atcacctgct ggtgagcaat caactgcgag
    29521 gaagacttct gggtcaaact tggttgtaga ggtatgagcg ccacgcagac caacttcttc
    29581 ttggacgtta gaacccagat agagttcatt gccgagtttt tgacctgata aagcttcagc
    29641 tagctcgctt accatgagga caccgtagcg gttatcccaa gcttttgaga tgatattttt
    29701 ttcattggct gtcaaaattg cagaactatc tggtacgatg gtatcaccag gacggatgcc
    29761 aaaactttct gcctcagcct tgtccgcaaa accaccatca aaaacgatat cggcaatggc
    29821 tggcatggtt ggtcccccct ttccacgagt caaatgcgga ggaacagaac ctgaaatcac
    29881 aggaatttca tgaccatcac gagtcaagag tttgaaacgt tggctgctaa ccaccatggg
    29941 gttccagcca ccgatttcta cgacacggaa ggtaccatct ggcttgattt cgctgaccat
    30001 aaaaccaact tcgtccatat gagaagcgac caagacgcgc ggtgcatcca cagcttctga
    30061 atgtttgata ccaaaaatac cacccaagcc atctgtcacc acttcatcca catgcggtgt
    30121 caacttttca cgaagataag cacggacagg cgcttcatga cctgagactg cagcaagttc
    30181 tgttacttct ttaatttttg aaaataatgt tgtcatttca gttccttctt tctttcatcc
    30241 attttaccac tttttatagg agaaggatag tgggaaggtg gatttctaag ttagtatctt
    30301 agtcctgctc tatcttagaa aaggatagta ttctcttgca tgtagtgcaa aatctagtaa
    30361 acattccaaa attaactcga atatttattt ccaaacaaaa aaacaataca ccatcaaagt
    30421 tgtttggatt tttcatgaaa tttacagaaa atagttgact tccctttctt ctttctttaa
    30481 atatatagtt ggttgagttt ggaatagtac gctgtagctg ctgaaacatt tctagaaatt
    30541 aatttgactt tcctaataga gttgttcata tcttatttca atttactata gtacaaaact
    30601 agaaaaggaa aaaatcatga ccaaaacaat tcttgttaca ggtgggacta gctacattgg
    30661 ctcccatacc gttaaagctc ttttaaatgc tggctataag gtgcatggcc tcgataatct
    30721 ctccacagga aatcgagcgg ctgtggatag tcgtgctagc tttaaagaac tggatgttta
    30781 tgatgctagc gccttaaagg cttacttaga agaaaatcag attgatgctg tcctccattg
    30841 tgcaggtgaa attgttgtga gcgaaagtat tgaaaatcca agtaaatact tcactgccaa
    30901 cgttgctggt atgaaccaag ttctcaaagt cttatctgaa gttggcattc aaaaaatcat
    30961 gttctcttcg actgcttctc tctatggaaa taactgtatt gacaagccgg tgactgaaga
    31021 taccctgctc gaccctgtca acccttatgc agagacaaaa ctgatgggcg aacgaatgat
    31081 ttactggatg gccaatcgct acgactggaa atatgttatt ttccgttact ttaatgttgc
    31141 tggggctgaa atggatgctt caaacggtct gcgtgtgaaa aatccaactc acatcattcc
    31201 aaatatcaac aagaccgcat tgggacaaca tgatagctta aaaatatttg gagatgacta
    31261 cgatacacgt gacggttcat gtattcgaga ttacatttat gtcttggacc ttgcataggc
    31321 tcatgttaaa ggaatgaact acctatttca agaagacagt tcttctcaaa tctttaactt
    31381 aggaactaaa aaaggctata ctatcaaaga aatctttaaa actgctgaag aattactaaa
    31441 ttaaaaaatc ccacacgaga ttgttgctcg acgtgctagt gacccagcca gtgtcctagc
    31501 agatgcttca aaagctaaac aatatcttga ttggacggct agctactccc tcgaagatat
    31561 tattttatca gattaaggta aaaacatttt agaataggat aacaaaggag aaagtcttgt
    31621 tgctctctcc ttgttgtatt tattaaattg tcagaaattt tattgacaga ttagaaaaat
    31681 aatgttacat ttatatccgc agatatcttt cgataccaaa tctacatgaa aggacggggt
    31741 atgaaacttt ctcattattt aattggctta cttctactcc tagtctttct ctctattagc
    31801 attgggacca gtgatttttc atggggaaag ctatttgatt tcgaccagca gacctggctc
    31861 ctctttcaag agtcccgtct cccaagaact atcagtattc tcctgactgc ctctagtatg
    31921 agtatggcag gccttctcat gcagactatt acccaaaatc agtttgctgc accgagtaca
    31981 gttggaacga ctgaagccgc caaactggga atggtgctga gcctttttgt ctttccatcg
    32041 gctagtctga cccaaaagat gctcttcgct tttgtttcat ccatcgtatt caccctcttc
    32101 ttcctagcct ttatgaccat ttttactgta aaggaaaggt ggatgttgcc tctgattggg
    32161 atcatctata gcgggattat cggctcagtc acagaagtta tcgcctatcg tttcaatctg
    32221 gttcagagta tgactgcctg gacccagggc tccttctcca tgattcagac ccatcagtat
    32281 gagtggctct tcttaggcct catcatcctg ataaccgttt ggaaattatc ccaaaccttc
    32341 accatcatga atctagggaa agaaaccagc gagagtttgg ggatttccta ctccctactt
    32401 gaaaaactgg ccctctttct ggtggcgcta acgacaagcg tcaccatgat taccgtgggt
    32461 ggcctaccat ttctcggagt tatcgttccc aatcttgttc gcaagcgcta tggagataat
    32521 ctaagtcaaa ccaaactcat ggtcgcactg gttggtgcca atctagttct ggcttgcgat
    32581 atcctatccc gagttctgat taggccctat gagttgtctg tcagtctctt gctaggaatc
    32641 atcggtagtc tcgtctttat cctacttctc tggagagggg gacgaaaaga tgcagactaa
    32701 aagcaaacat accaagctct tctggattct cattattctt gccatcggag cttgtcttct
    32761 ctacttttgg cccatcactc acttgtcagc ctttgcttgg aagttgcgtt cccaaaagat
    32821 catcgtttat ctcttggtag ccatcgcgac tgggatttcg accattagtt ttcaaaccct
    32881 gacggaaaat cgcttcctga cgcctagtat tttgggaatt gaatccttct acatcctact
    32941 acaaacccta ctactggttt ttgaaagcaa gtttcttcaa cttggcaaat cccctatctt
    33001 agaattccta gtcttacttc ttgtccagtc cctcttcttt ctcgccttac aaggttactt
    33061 gaagacactg atgaagcaag acctggtctt catcctgctg atctgtctag cgctcagaag
    33121 tctctttcga aatatcagca ccttccttca agtcctaatg gatccaaacg aatacgataa
    33181 actgcaaaat agtctttttg cctcctttca acatctcaac acttccatcc tagccatcgg
    33241 ttctctgatc atcctcgctt tgacaatctt tttctttcga aaagcagtcg ttctagatgt
    33301 cttgcacctg caaagagaaa cggctcagat attgggactc gatgttgaaa aagaacagaa
    33361 agagctcctc tggggaatcg tgcttttgac ctcaacggcc actgccttgg taggacctat
    33421 ggccttcttc ggctttatgc tggccaacct cacctacctg attgtcaaag actatcagca
    33481 caagttactc tttatagtgg ccattctgat tggatttatt agcttaacct tggggcaagc
    33541 cttgattgaa cgagtctttg cactggaaat tcgtatcagt atgatcattg agagtgtggg
    33601 tggcttctta ttctttatct tactatatag gaggtctcgt cagtgaaact ggaaaacatt
    33661 gacaaatcca ttcaaaaaca ggatattttg caaggcattt cgcttgaagt cagtcctcaa
    33721 aaactgacag cctttattgg tccaaatggt gctggaaaat cgactctcct ctccatcatg
    33781 agcagactaa ccaagaaaga tcagggagtt ctcagtatca aaggacgtga aatcgagagc
    33841 tggaattcgc aagaactggc ccaagaacta accatcctaa aacagaaaat caattaccaa
    33901 gccaaattga ctgttgaaga actggtcagt tttggacgtt ttccctacag ccgaggtcga
    33961 cttagatcag aagactggga aaaaatccga gaaactctga actatttgga actgaccaac
    34021 ttaaaagacc gctacatcaa tagcctgtca ggggggcaac tccagcgcgt ctttatcgct
    34081 atggtactgg cccaggatac ggactttatc ttgctggacg aaccactcaa caatctcgat
    34141 atcaagcaaa gcgtcagcat gatgcagatt cttcgacgac tggtggagga actcggcaag
    34201 accattatca tcgtcctcca cgatatcaac atggccagtc agtatgcaga tgaaattgtc
    34261 gccttcaagg acggccaggt ctttagcaag ggaagaaccg atcaaatcat gcaggctgac
    34321 ctactcagtc aactttatga gattcccatc acgctagctg atatcaatga caaaaagatc
    34381 tgtatctata gctagtaaca taaaagctca agttagagaa ccttcagtct cttagtcaat
    34441 aagattaaga gactccctaa atcgttatca cattttaaaa aggagaaatt atgaaaacat
    34501 cccttaaact ttatttcact gccctagtgg ccagcttctt gctcctactt ggtgcatgta
    34561 gtacaaactc aagcactagt cagacagaga ccagtagctc tgctccaaca gagataacca
    34621 ttaaaagttc actggacgag gtcaaacttt ccaaagttcc tgaaaagatt gtgacctttg
    34681 acctcggcgc tgcggatact attcgcgctt taggatttga aaaaaatatc gtcggaatgc
    34741 ctacaaaaac tgttccgact tatctaaaag acctagtggg aactgtcaaa aatgttggtt
    34801 ctatgaaaga acctgattta gaagctatcg ccgcccttga gcctgatttg attatcgctt
    34861 caccacgtac acaaaaattc gtagacaaat tcaaagaaat cgccccaacc gttctcttcc
    34921 aagcaagcaa ggatgactac tggacttcta ccaaggctaa tatcgaatcc ttagcaagtg
    34981 ccttcggcga aactagtaca caaaaagcca aggaagaatt ggccaagcta gacaagagca
    35041 tccaagaagt cgctactaaa aatgaaagct ctgacaaaaa agcccttgcg atcctcctta
    35101 atgaaggaaa aatggcagcc tttggtgcca aatctcgttt ctctttcttg taccaaacct
    35161 tgaaattcaa accaactgat acaaaatttg aagactcacg ccacggacaa gaagtcagct
    35221 ttgaaagtgt caaagaaatc aaccctgaca tcctctttgt catcaaccgt acccttgcca
    35281 tcggtgggga caactctagc aacgacggtg tcctagaaaa tgcccttatc gctgaaacac
    35341 ctgctgctaa aaatggtaag attatccaac taacaccaga cctctggtat ctaagcggag
    35401 gcggacttga atcaacaaaa ctcatgattg aagacataca aaaagctttg aaataagcca
    35461 cttcaaactc aatttaatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag
    35521 gttgctcaaa acactgtttt gaggttgcag atgaaagctg acgcggtttg aagggatttt
    35581 cgaagagtat aaaattttga cattctaaaa cgcatcctat caagttcact caaacctgat
    35641 aggatgcgtt tttatcattt tgaaatctat ttaccccacc tcattcccct tcttgatttc
    35701 gtttaaggga aaagtggtct ggaacagggt ccttacctgt tttcgaccag ggatgacaac
    35761 gtaaaatccg agccaagccc atcaatactc ccttaaaacc atgtttttca atagcctgaa
    35821 tcatgtagtt ggaacaagtc agatcaaagc gacaagaggg tggaaagact ggtgagataa
    35881 aacgttggta aaagcgcaca ggcgctatta aaattcgttt cattatttct tagttacagc
    35941 catggtgtgt agttggctga tttctttttt attaagacga cgggattctc ctggacggag
    36001 tcctgtcaag tctaggtgtc cgaaacgagt ccgagacaac ttatctactt ggagaccaac
    36061 agcttcaaac atctttttaa cctgatggtt acgcccttca tggatggtca actgcaccac
    36121 agagcgattt ttgactgggt ccactttgag aatttcataa acagctggct tggttttctt
    36181 accatcaatc tcaagaccac gggtcaaggg gcggagattg tccttattgg ccacaccttt
    36241 aacacgcgcg acataaacct tgtcaatctc attacgaggg tgaatcatct cgtctgtaaa
    36301 gtccccatca ttggtcaaaa tcaagacacc tgatgtatcc cagtccaaac gacccacagg
    36361 gtaaatacgc tctttgacat tgggcaagag gtcgacaacc gtcttgcgac ccttatcatc
    36421 tgtcacactg gaaatcacac cgcgtggttt gttaagcaga tagtagacct tttcttcgtt
    36481 gtagataggt tgaccttcaa cttcgacctt gtcgcctgac ttgatagtgg ttgctagttc
    36541 acgcaccact tggccgttaa ccgtcaccaa gccttgctta atcagctctt ctgcttttct
    36601 cctactggcc acacctgcgt gggcaatata cttattgatt ctcatcttct tctatccttt
    36661 caccaaataa ttggctttct tgggcttgaa tctcaagctc atcaatcact ggtaattctt
    36721 ctaaatggtt tatccccatg taatctagga aataatccgt agtcacatag aggttggggc
    36781 gccccaatac ttcctttttc ccgtcttcct ttatcaggtc aaaagcctgc aactttgcca
    36841 aggctccact cgagttaact ccacggatgg catcaatttc tatccgcgta atcggctgtt
    36901 tgtaggcaat aatggacaag gtctcaaggg cagcccgaga caagctctgg ttgataggcg
    36961 ccttagagta ttccttcaaa atctctgcaa attgaggctt ggtcaccaat ctataagcac
    37021 cacttgtctc aatcaaagcc aaactggaat ctgggtcctt ttcatacttc tgggctaatt
    37081 ttcctaaact ttgctggatg cctgtcggtg gcagagagag gagttcagct aactggcgga
    37141 cccgaatccc atcttcaccc gctacaaaca agagcgcttc tatttttgct aaagtactca
    37201 tctttcctct ctatcaagtc tagctttgag gcacttgact ttcttccttc ttttccatga
    37261 gatagatatc tccaaaactc tcctcttgca cgaggatcag ctcctgggtt ttgattaact
    37321 ctagggttgc caaaaagagg gtgatgacct cttggacatt ctgggcttcc ttgaacaaat
    37381 cctgcaagcg caattgatct cgtccaatca aggactcttt cacgataatc atcatgtcct
    37441 caatcttata ctcatcccgc aagatcgtcg tgtgattttg tgcaaactcc tcttttttct
    37501 tggctaggat atttgaaaaa gccaaaaaga ggtcaatggt cgtcttgtca tgcacaagct
    37561 ccgcatcttc gtaaatcaac tctgtcggcg ctttggaata atactgggcc cgttcttggt
    37621 gcttggcttc caagtgctca cccaagagct tgaacttgcg atattcttcg atttgagaga
    37681 ggaggtcctg ctccaggtca tcccccaagt ctgtcacttc tgctaccttc ggaaggagtt
    37741 tacgactctt aatcagcatg agctgactag ccatgaccat gtactcaccc gtcacttcca
    37801 gacgcatggc ctgcagggtt gagacatagg ctagatactg ttcgatgact tccgtaatgg
    37861 gcacatcgta gatatccatc tggtacttag aaaccagatg caagagcaag tccaggggtc
    37921 cttcaaaatc ttttaattta atatccatta tctatatttt tctaaggtca ggactgtttt
    37981 taatcctaat ttttttgcaa tttcgtacaa atcgaccttg ttttctattt gtcttagaat
    38041 aaactgttca cgtaagactt gagctgataa ggatggaaaa cctttctcct tgacaaaaga
    38101 ttctaactga cgaaaggccc actgacgaga atagggtttc tctcctcttt caaaaagata
    38161 ggtctgcccc atcaagggtt ccaattctga aagcaaggcc gtgggaatgg tgacaatcct
    38221 ctgttgggaa gccttgctga ttcgcagcac ctgaaaatcc agattgatgt ccgcaacctt
    38281 gatggctaaa atctcactgg gcaagagccc catttctagg attaagagcg ctagcaagcg
    38341 gccctctgga tggtcgcttt cctgccaaaa agagtctagg tatagaatct ctggcttttc
    38401 cgtcttcttt tcagcttgtt tggctaattc caagcggtaa aagctgtcca cctctccttt
    38461 ttgatagaga aagtatagaa attggttaca ggccgaaatc tttcgcttct gggcgctgat
    38521 ttttagattg gctagctggg cttggtaaat cttgagactg gtctcagaaa tccgctcacc
    38581 taccatgtct aaaaattgct ccaaatcata cttataggac tgcttggaat tgacagacaa
    38641 gccctgcttt tcctctaaaa aggctgaaat cctgtctctc attggcatcg aatctcatat
    38701 tccttactaa agtcatgcaa gagggcatta acggccttga ggatggactt gcgcgtaata
    38761 atcccttgga aaataccctc tgcatccacg accggtaaga aggactcatc tactagcttg
    38821 tgcaagacct ccgtaatggt gaaatcaggc gaaacaaccg ctacgtccgt ttttgtcata
    38881 tgaacgatat ccgtatccgc catgatttct tggctcaagt catgctccat ctgataagcc
    38941 ataatatctc tgagtccaat cgtcccaaca aactgttttt catctgtcac aacgggaaca
    39001 cgggtatagg tcatctgact gagcaagagg gtcgcatgat ccgcattgtg ggtatcaatc
    39061 aacacagcta gatttttagc aggggtcaaa aaagtttcct cctgccccaa caagaaagtc
    39121 tcaaactcct tggcaatcat cggctaaact ccttggacaa acctggatac acctcgtgat
    39181 ctcgtgtcaa aaagtccact ttgaagtaac tatcatcaat ctccacacga gcatagagac
    39241 attctctgat ggtacctcgt ggttgactga tagaacctgg atttagaaag aggatcttgc
    39301 cttccaacca agcacttggc acatgcaagt gaccatagag gcagatagcg gcctcttcct
    39361 cctgagccca gtagtccaac ttttgaaagt tgaaattgat gtcaaacaag tgaccatgag
    39421 tttggataat cttggtcgaa ccaagctcag tcaccagacg ttctgggtag ccggcgtaga
    39481 agtccatgtt ccctttaaca acgcggatgc cctcccaaag tggagaatcc ggacgtagtt
    39541 cagaatcgcc gttatgaaaa acggcatcga ctttgcccac atagcgatca cggacttctt
    39601 ccacaatcaa gctatcgcca tgggaatcgc tcattacaat gatggtttgc tttgccatga
    39661 tggaaatacc tccaaaagtt tcttaacggc taaggcacgg tgagattgac tatttttttc
    39721 ttctagggtt aattcagctg atgactcacc tgtctctcct acaaggaaga ggggatcata
    39781 gccaaagcca ttttcaccct taggttcaaa gttaatataa cctgaccagt ctgcttcaac
    39841 aactaaactt tccttatttg ggctggctac gactagggtt gtgtggaact gagccgagcg
    39901 gtccttgagt tcaaagacca tggccaattc gtgcaagagt ttggcattat tttcacggtc
    39961 agttgctccc acacctgcga aacgagctga ccagacgcct ggtaagccac caaggacatc
    40021 gactttgaga ccagaatcat ctgccaaaac catcttaccc gttaattgag aaatggtttc
    40081 tgccttaagg cgggcatttt cttcaaaggt catacctgtt tctgctactt caggcaggtc
    40141 agggtagtca ttaagatttt ccacatcgta gcctaactta tcaaagatag ctcggaattc
    40201 cttggttttg ccttcgttac gagtcgcaat caacaaggtt tctctgacct tgcttgtctc
    40261 aaagaaatca tgaacattga ccccttcttt aggcaattct acatacaaga gttgcccatt
    40321 ttcaaccaag agcagggccc catgacgttg aataacttcc aagtttcgtc ccatttcttg
    40381 attaagcata tctaccacaa aggagaacaa acggtaggta gaaccatagc gtaaaacagt
    40441 aactgaaagc gggaaaccat actcttcatc tccaaatatt ttggagaatt caaacagagg
    40501 aaaatctgtc ttatagtcgc tcaaactgtt aacgccacca aaaatactat aagacccaac
    40561 ataccagtcc tggtcatcct tatattcata aattttattt gtcataattc tacatgctcc
    40621 acatgaatct ctttttccag ccattcttca ccaatttgtg caaaactttg gctactggct
    40681 gttgtgtaaa aacggtgatg gagtggtcca gcatcgcgac cacgattgat ttcaaaataa
    40741 ttgagtaaga ctgagatatc ccgtacgcac tctgccccac tatcgatgag ctgaaccttt
    40801 ggccccatca cattttggat aatagggcga aggagtggat aatgagtaca gcccaaaatc
    40861 aggctatcca cctttccaac caagggacgc agggtttcat agaccacctt cttggtaaca
    40921 ctggttgaca gggcacctga ctcaaccaag ggagcaaact tgggacaggc caagctctcc
    40981 acctgtaagt cgggatccag atcatggatt ttctgacggt atatgtctga ttgtaccgtc
    41041 atgggcgttc caatcactcc gattttccca ccttgactgg acttgatggc tgccgaagct
    41101 cctggcaaaa ttacacccaa gacaggaata tctagttgag ccttgatttc ttcccagacg
    41161 accgcagtcg cagtgttaca agcaatgaca atcattttga catccttggt caagagaaag
    41221 ttgaccagct gccaagtata ttcacgaatt tgctcagcag gacgggggcc atagggcgcc
    41281 cgcgccgaat ctccaatata gacgatttct tcatggggaa gctggcgcat gagctcgcgc
    41341 acaacggtca agcccccgac acccgaatcc aaaaaaccaa ttggtcgatt atccatacag
    41401 tcttctttct agtctttttt ctgattgatc gttcattatg attccttgtc ctgaacgaac
    41461 tgaccgacag cttgatagaa tgtcaactac ctctctctta atcataatca aatatcaata
    41521 gaatgcaagg aaaaagtctc atccctaaac cataaccaac atagtgagaa gtctggaact
    41581 ttcatcccag acttttcctt atttattttt tctttttatt gttagcaagg gctgcctttt
    41641 gttggcggat gatttggtgg taaacttgtt gtaccttagc ttcgcttggt ttttgaccat
    41701 ttgcactcaa aagagtacga actgcttcag cattcaaacg tgggttgtca gcaaattctt
    41761 tttcgatttg cttacgaacc aagtacattc ctccaagagc tcctcctaga aaagctagca
    41821 caatcaatac aattgctaaa agtaaatcca tcatttttct cctgtttctt tttgagtccc
    41881 tttcattata ccacaaacta gccaccctga ccagtttgtt ctacactttc agggatggaa
    41941 tagacagcaa aaagaaccct gcttttctga aaaagaggtc tccttgctaa gtttatactc
    42001 aatgaaaatc aaagagcaaa ctaggaagct agccacaggt tgctcaaagc accgctttga
    42061 ggttgcagat aaaactgaca cggtttgaag agatttgcga agagtattaa tttacataaa
    42121 tagccagtgt ttgatagggt ttgagtagaa ttttctcaga cacttctgca tcttcatagt
    42181 ttgatatcaa aatctgtcca ttttggtaga ctgctggcaa gtcgatttcc acttctttag
    42241 cataaaagtt attgagcact agtaactttt gatcctcaaa ctggcgttca aaagcgtaga
    42301 cttgtttgct atcttcaaag gctggtttgt aacttccttc tgaaatgatt ggcatttcct
    42361 tacgcagtcg aatcaagtct tgatagaagg taaaaatcgg accctggatt tcattttcta
    42421 cattgatgtc tttataggat ttaccagctt tcaaccaagg agtgcctgtt gaaaatcctg
    42481 cattttccga agcatcccac tgcatgggaa tgcgtgaatt atcacgcgac ttagcttgaa
    42541 taatctggaa ggcttcttgc tgactctttc cttcttctaa gagcatctga taggcattaa
    42601 gcgattcgac atccacataa tcagccatag aatcatagtc tgggtcaatc atcccgattt
    42661 cctcacccat gtagatataa ggtgtcccac gtgacaggtg aatgctggcc gctagcatgg
    42721 tggctccttc cttgcggaag ttttgaatat cgacaaaacg gttcaaggca cgtggttgat
    42781 cgtgattgtt ccaaaagagg gcactccaac cgtctttatc actcatttcc ttaccccaac
    42841 tatggtaaag actcttcaac tcttcaaaat caaagggagc caaggtccac ttttgtccat
    42901 ccttatagtc caccttgagg tgatgaaaat taaaggtcat ggataattcc tgacgatcag
    42961 gcgacgaata aaggacacag ttttccatgg tggtagaaga catttcccca actgtcataa
    43021 agctatcgtc agatccaaaa gtggcttggt tcatcatacg caaatagtta tgaacgatgg
    43081 gtttgtctgt ataagctggc ttcccttcat tttcaggaca gtccactgaa acctcgtcct
    43141 taccgatcaa attgatcaca tcaaatcgaa aacctttgac acccttgtcg cgccagaaat
    43201 taacaacctt gaaaagctcc ttacggacat tgggattgcg ccagttaagg tcagcctggg
    43261 tctcatcaaa taggtgaaga tagtatttcc cagtatcccc gaaaggcgcc catgcagaac
    43321 caccaaactt agactgccaa tctgttggtt ggtcttggat gaagaaaaag tcttgataat
    43381 acttatcacc agctagggct ttctgaaacc attcatgctc tgtcgaacaa tgattaagta
    43441 ccatgtccag cataaagtca atcttgtgct ctttaccgat acacaccatt tcctcaaaat
    43501 cagccatatc accaaaaaga ggatccactg ccatataatc tgaaatatcg taaccattat
    43561 cccgttgagg acttggatag aatggattga gccagaccat atccacacct agtttggcta
    43621 gatagggaat ttttccgata atcccacgga aatccccaat accgttttca gtggtgtctt
    43681 tgtaagattt tggatagatt tgatagacta cttttccttt atcaagtgtc atctgtttct
    43741 ccttttctga taaaagggag gaagcagtct tccgtcccta tttgtgctat ttcaattata
    43801 ctcaatgaaa atcaaagaac aaactaggaa gctagccaca ggttgctcaa aacactattt
    43861 tgaggttgca gatagagctg acgtggtttg aagagatttt cgaagagtat tagattcgtg
    43921 tagcgaccat gagagatgct ccagcttgga tcgttgtcgg ataagttccg ggaatagtcg
    43981 ctgtataagc atcttggttg gtgatgataa caagagtttc tgtcaccaga cctgcagcct
    44041 taatgacatc catatcaaaa cgaatcagtt gctggccaac tataacgtga tctccttgga
    44101 ctacaagact ttcaaaacct ttgccatcaa gacctactgt atccataccg atgtggatga
    44161 gcaattcaac tccctcgtca gagacaatgc cgatggcatg cttggtaggg aaaagaaccg
    44221 tcactgttcc attaactgga gaggtcaact caccttggct tggttcaatg accagacctt
    44281 gccccatgac acctgatgca aaaacaggat ccgtcgcttg actcaattct ttcacttggc
    44341 cagttagtgg gctgataatt tctaccgaag taagttctac tagttcatgg ctcacaaatt
    44401 ctgcttcttc ttgagcaacg aattctgcct gcaagttcgt atcgccctct gtttttgtaa
    44461 agagaccagc cttgcggaag aagaaagtca agagcattgg aacaacaatc gcaactagca
    44521 tagttcctgc aaatggcagc atgtattgag gttgaataga gagaatacct ggcaaaccac
    44581 cgataccaat agaagccgca gttacattaa aagtaacgga taacatgcct gcaagggctg
    44641 aaccagtcat cccagcaaca aatggataaa tatattttac gttaacccca aaaagagctg
    44701 gttctgtaac accgagatag gctgaaatgg ttgcaggaag tgaaacctga gcctcacgct
    44761 catcatggcg atgcatgaaa taataggcaa acacggctga gccttgagca atattagaaa
    44821 gagcaatcat aggccagagg gcagtgccac cagcatccgc aatcaattgt gtatcaatgg
    44881 cattggtcat gtggtgcaga cctgtgatga caaatggagc gtagagggca ccaaaaattg
    44941 caccgaagag ccattttaca ggacccgtta aacctgccaa tacaactgat gaaagtcctt
    45001 gtccaattgt ccaaccgatt ggccccaaga cagtatgagc caaaatcaag gctggaatca
    45061 atgacaaaaa aggtacaaaa atcatggaaa tgacttctgg gatatgtttg cgccaaaaaa
    45121 tttcaagata agacagactc aaacctgcaa gcaaggctgg gataacttgg gcttggtaac
    45181 caatacgatt aacagtaaaa taaccaaaat tccaaaccca gtttgctgcg atatcagctg
    45241 ctggcgttga agcaaccgca taggcattga gcaactgagg cgataccaaa cagattccga
    45301 gaacaattcc caaaatttgg ctggttccca tcttacgaga aacagaccaa gtaatcccta
    45361 ctggtaagaa ctggaagata gcttcaccag gcaaccagag gaagtgatta acccctgccc
    45421 aaaactgaga ggattctgtg atggtcttgc catccaacat cgaccaatgg acaccttcca
    45481 agacattacg gaaaccgagg atcaatccac caacaatcaa ggctggaata atcggagtaa
    45541 agatttccgc cagagtggtc ataacacctt ggaccacgtt ttgattactc ttagctgcag
    45601 acttggctgc ttctttggaa acaccctcaa tacctgaaac ggctgtaaaa tcattataaa
    45661 agatgggcac gtcatttcca atgattacct gaaattgacc tgcatttgta aaggttcctt
    45721 taacagctgg aattgactcg atagctttaa cattagcctt cttatcatct cctaaaacaa
    45781 accgcatccg tgtcgcacag tgggtgacgg cagtcacatt ctctttacct ccaattgcct
    45841 gaagcaaatc tttggcttct tgttcaaatt ttcccatttg attctcctta tacttgtcaa
    45901 agcaagtttg atttgataag tatattgtaa acgataccaa acttgtctgc aacttgtttg
    45961 gtataaaaag ggtgtttttt tgtaaatttt ctagcacttg tatggtaaaa tagatacagg
    46021 tgttcattaa actagactaa aaacctattt aagaaagcaa aatgaaaaaa taccaacaat
    46081 tatttaagca aatccaagaa accattcaaa acgagactta cgctgtcgga gattttcttc
    46141 ctagcgagca cgaccttatg gagcaatatc aagtgagtcg tgataccgtc cgaaaggccc
    46201 tgtctctcct ccaagaggaa ggattgatca aaaagataag agggcaaggt tctcaagtcg
    46261 tcaaagaaga aaccgtcaat ttccctgtat ccaacctaac cagctaccaa gaactagtta
    46321 aagaacttgg actgcgctct aaaaccaacg tggtcagtct ggacaagatt attattgata
    46381 aaaaatcctc actgataacc ggtttcccag agtttcggat ggtttggaag gtggtccgcc
    46441 agcgtgtggt ggatgatctg gtatccgttc tggatacgga ctatctggat atggaactaa
    46501 tcccaaatct cactcgccaa attgctgagc agtctatcta ttcttatata gaaaatggcc
    46561 tcaaactcct tattgattat gctcagaagg aaatcaccat tgaccactca agcgaccgag
    46621 acaagattct catggacatt ggcaaagacc cttatgtcgt ttcgattaaa tcaaaagtct
    46681 atctccaaga cggacgccaa tttcagttta ccgaaagtcg ccataagtta gaaaaattta
    46741 gatttgtaga ttttgcaaaa cgcaagaaat aaaagactga gacaccagat ctcagccttt
    46801 ttctttatcc caaaactaat tcatcactga ccagactttg gccactattt ttctggaaga
    46861 gatgcataag gtcttcaact gtcagatgct ttttctcttc tcccttgaca tccaccacta
    46921 tcttgccttg atagagcata atgagacgat tgccgtactc aatcgcatga ttcatatcat
    46981 gggtaatcat caaagtcgtc cactgatggt gctccacaat cttttgcgtc aagtccatca
    47041 ccatttgact ggttttcggg tcaagtgccg cagtatgttc atccaaaagt aaaagttttg
    47101 gtttcatcag atctgtcatg actagagtca aagcctgtct ttgtcctcct gagagatatt
    47161 gagtatctac ttttaagcgg ttttcaagac caatattcaa ctccttcaag gcctcttgga
    47221 actggattct atccttctcc ttcacgcccc aaccaagccc tctcttctgc ccgcgtctca
    47281 aggcaatagc catattctcc tcaatcgtca aacgagaagc tgttcccatc ttaggatctt
    47341 gaaaaacacg ggcaatatcc ttggctctct ttctgacact cagattttta atggatttcc
    47401 ctgccagtag aaggtcccct tcgtccaccg atagattgcc agccaagata ttcatcaaag
    47461 tggattttcc tgctccattt ccaccaatca cagagataaa atctccctct tcaacctcta
    47521 aatctaatcc tttgaggaca tggttctcat tgaccgtccc tgcttcaaat gtcttgtgaa
    47581 tattttcaag tgttaacaaa cttgccataa ctttctcctc ctattcattt ctcaatttca
    47641 gaccacgaat ctttaatctc ttttgcaatt ctggtgcaaa taaaaccaaa gcgagcaaga
    47701 ttgcattaaa gagacgtacc aagttttgat ctagatttgg aatttcatag atatttaaaa
    47761 taatcaaacg gtaaacaata gcaccgattc cgatggataa taagcggcct ccaatggtca
    47821 agtcgtgtat caagacttcc acaataatca ccgagctcaa accaacaaca atggttcctg
    47881 tcccagaagt cacatctgaa aatccatcat tttgggcaaa caaggaacca catagagcaa
    47941 tcaaaccgtt tgaaatcatg taaccaacaa tcttcatggt gtctacattg actccattgg
    48001 cctcactcat cgggatatta tccccagtcg aacgcaagac caagccaatc tctgttttca
    48061 tcaaaagggt caagaccaaa caaacaagta aaaaacaggc caaactaagt gagaaaacag
    48121 ttccttcatt tgtcagaccc aagctcgcca actgtttaaa gacggttgca gaatctccca
    48181 aggaaagatt gggtacactg cccatgattt taatattgat tgaatagagc cctgtcaagg
    48241 tcacaatccc tgtcaagaga gctgggattt tcatcttggt gtggagcatt cctgatacaa
    48301 gacctgctac catacctgcc agcaaagcaa gtaaagtcgc aagccaagga tttgcccctg
    48361 cctgtatctg tgatacaacg actgctgccc ccagaggaaa ggctccctca gcagtcatat
    48421 ccgcaatatc caaaatacgg aaagtcaagt agaccccaat cgccacaatc gaccacaaca
    48481 aaccttctga taaactagat aacacaaaat tcatcttaat cctccttatt ccttgccttc
    48541 taacttacta atatcaattc ccaatgcatc tgccatttct tgattagtat gcaattccag
    48601 tttttcaggc aactcaactg ctatattttc tggtttctca ccttttaaaa catgaatcag
    48661 catgcgagct gtctgtcttc ccaattcttc ataattggtt ccgtagttat acaagccacc
    48721 aacagcaatc atttctgttg aaccaccgaa tactggaacc ttgtgtttaa tagaaacctg
    48781 cttaactgtt tccatggtta acgaaatgat attatcagtt gggacaaaaa ccatatccac
    48841 ctctgccatc aaactctctg ctgccgcctt gacgttatta ctgtccaaga ttgttttttc
    48901 aacaacggta aagccttttt ctttcagaag tcgcttagct tcatcctttt gaacaaccga
    48961 attgggctcg ctctgagcag aaggccttgc gatggctaga acgacatcgc tggattctgc
    49021 tagttgctgg gaaatcgttt ttagatttct ttgttctccc tgtgcatttt gcaaatcaat
    49081 ctcaatattt tccccctcaa catagccttg tttggccagc tcatccacaa atccttctct
    49141 agtagcgtct aaggactggt gggtaataaa ctgcgaaata ccgatacgaa agacatctct
    49201 tttcttatct gccttcaact gatgcaaact gatcagagaa gtcaagagga tccccactac
    49261 caagaggggg ctagtgattt tcgaacaact ttcataatga aactccttct cagaaaagat
    49321 aaaacaaaaa accgcctaga tactatctaa acggatactt gaaataacct aacaagttac
    49381 aacttagcta gtccatttag atattcatct atatggacca caatcaaaaa tcttagccac
    49441 atagatacaa acaaattgct tgaactgttt gcatccatgg tgacatgtct acaaacacta
    49501 tctaaagtag ctaaagtaaa agttttgatt catagttacg gcttgtctct tattcatttc
    49561 tttttctgct ttcttttttg atgcttcctg tcctaccacc tttttcatca cctgtcaata
    49621 acatttcata atttttaaaa tttttcaaaa attctttcag gaagctttca aagtttttca
    49681 aatcagtcca acaaaaaaag ttttataatt tccataaaaa ttgacatgga aattataaaa
    49741 ccattactag tttagtcctt tttgataacg tgccaattcg gcttggttcg cccaaacata
    49801 gtgacctgga cggatttcta ccatagatgg cttatcagtc tcatagtcgt gttgacttgg
    49861 gtcgtaaacc ttcaagacct tcttacgttc caagattgga tctgggattg gtaccgctga
    49921 aagcaaggct tgagtatatg ggtgaattgg attgttaaac aattcttctg tttctgcaac
    49981 ctctacaata acacccttgt aaataactgc gatacgatct gaaataaagc gaacaaccga
    50041 caagtcatgg gcgatgaaga gataggtcag gccgagctct ttttggaatt ttttgagcaa
    50101 gttcaagact tgggcacgta cagaaacgtc caaggctgaa attggctcat ctgcaataac
    50161 aaagtctggt tgcatgacca aggcacgggc aataccgata cgttgacgtt gaccgcctga
    50221 gaattcatga gggtaacgag tcaagtgctc agcaagaaga cctacttcac ggataatatt
    50281 ttgaactttc tctttacgtt cttcttcatc cttaaataaa cggtgattgt aaagaccttc
    50341 agaaataata taatcaacag tcgcacgttc attcaaactt gcggcagggt cttggaaaat
    50401 catctggatt cgacgaatca attccgcagc ttgttcacgc gatttcttac cattaatctt
    50461 ttgaccatca aaaatgatat ctccattact tgtatcattt agaccgatga tagcacgacc
    50521 aatagttgtt ttcccactac cggactcacc tacaagcgag aaagtttctc ccttgttgat
    50581 aaagaagtta gcatttttaa ccgcgacaaa cttcttactt ccttcaccga aggaaatttc
    50641 taaatctttg atttctacta atttttcaga catttccttc ctcctagtca gccagatggg
    50701 caaatcccat tttttcacgg atcttatcat ggagatttgc aatcacagct ggtttttcta
    50761 cttttggagc atcctcatga agaagccaag ttttagccca atgtgtctct gatactgaga
    50821 attgaggagc tttttgttcg aagtcaatct gcattgcgta gtcagaacgc aaggcaaaag
    50881 catccccttt caggtcagta taaagtgacg gaggtgttcc tgggattgag taaagttccc
    50941 ctttatcatc agcaagctga ggcaagctag acaagagact ccatgtatat ggatggcgag
    51001 ggtcatagaa gacttcctca accgttccat actcaacgat ttctcctgca tacataaccg
    51061 ctaccttatc cgcaatactt gccaccacac caaggtcgtg ggtaataaag attgttgtga
    51121 aatgatactc gttttgtaaa gattttagca aatcaataat ctgagcttga atagtcacat
    51181 ccaaggcagt tgttggctca tcacagatca agacatcagg tcggcaggca agggcaatcg
    51241 caataacgat acgttgacgc attcctccag aatattggaa tgggtattca ttaaaacgtc
    51301 tatctgcgtc tggaatgcca accttattca tgtagtcaat ggccaattct ttcgcttctt
    51361 tagctgtttt tccttggtgt tttacaataa cttctgtaat ctgactacca attgttttaa
    51421 tggggtccaa actagtcatt gggtcctgga agatagtcgc aatcttagca ccacgaattt
    51481 gttcccaatc cttgtgagaa gataaagctg tcaagtcctg accacggtag tcaatactac
    51541 cttgggcaat acgaccattt tcttcgagca tacctgtgaa ggtctttgtc aaaacagatt
    51601 tacctgatcc tgactcacct accaaggcta atacttctcc ttcgactagt tcaagggaaa
    51661 cgccgcgaat ggctgtcaat actttgtcac gaacgtcaaa ttccacgaca atatcgcgag
    51721 cagtcaaaat tacatttttt tcttttgtca tttctactcc tatctatgtg tacgtggatc
    51781 actagcatcc gctaagtttt gaccaactac gaaaagggac aaggatacca agacaagggt
    51841 tgtcaatgga atccagaaca agtaagcatt ggttgttacg ttttgtgaat aatccgaaat
    51901 caaacgaccc aaacttggca ctgtaatcgg taatccaaga ccgaagaaag acaagaaggc
    51961 ttcgtatgag ataaagcttg gaagcatttg agtcatggtt gtcacaataa cagataccaa
    52021 ttgaggcatg atatttttgg caacaatctt caaggttggt gttcccaaag tacgtgacgc
    52081 caagttgtat tccaagtcac gatagcgcaa gatttgcaca cggatcatga aggcaatacc
    52141 aatccatgtt gttacgctca tggcaaaaat cagattccag aatccagctc cgattgagta
    52201 agttaagaca ataacaatca aaagaggtgg gatgtttgag atgacgttgt aaacttccat
    52261 catgacacgg tcaactgatt ttgaaatacc ccaaatacca ccgacaaaaa caccgataac
    52321 caagttaatc actgtcgcaa tcacagaaat gaggatggag ttacgagctc cgaaccagac
    52381 accgtcaaag agcgatttac cgttactgtc agtaccgaac caatgctccg catttggctt
    52441 gatataacga acactaaagt cgtttacctt gctgacatca ttgaaatcaa acttagaaaa
    52501 cattgggtag atgaaactta tcaaaatgat ggctaccaag attcccaaca tgactacagt
    52561 tgattttttc ttcataaatt gtttaaacac tgatttccag taagaatatg ctggcgcatc
    52621 aatagtttca gaggcaaaat cgtcacgttt tacaaactga aatttttctt tatcgattgt
    52681 agacattatt tgcctccttt ctcagtcaat ttaatacgtg ggtcaataat agtcatccaa
    52741 atatctccca aaagacgtga gaagatagaa atacatgtaa agatgaagac aagaccaacg
    52801 accatagagt tattagatgc ttttacagag tcaatcaaca ttttacccat acctgggaag
    52861 gcgaagactg tttcagtaag ggttgcacca ccgataaccc caataatggc accaggaatt
    52921 cctgaaacca gcggaaccat ggcattttta aagatgtgtt tgtttgaaat ttctttttca
    52981 gacaaacctt ttgcacgagc gaaacgaaca aagtcttgag attgcaagtc aatcatgtaa
    53041 cgacgaatcc aaatggctgt accaggagca cccaacaaac caaggatgac tgctggtaaa
    53101 acgtaagaac gccaatctcc agctcccaag atagggaatg aatctggaag ggaaatagat
    53161 gatccaatca atcgaacgat gtaaaccaag gcaatcgttg gaagagcaag caagaaggtc
    53221 aaagcccctg ttgagaggct atcaatccaa gtgttcttga aacgagccat ggctgaacca
    53281 agtggcacgg caagagcata ggcaagaacc aaaccaatca aaccagtaat agcagagctg
    53341 acaatcatag atggatattg gtaattactt tcagtcgctg tataaggatc atctttccca
    53401 tagctagcta cttcacgaga gtcagcctga ctaggtgact tgtaggttct tgagtaaata
    53461 tttacagaag acgttttctt acctgttggg aactgaactt gggcagtttt ggtttgtcct
    53521 tgaccttgag taataacctg aagaactggt gtattagcat aggttgggta agagtcacct
    53581 aaattcaagt tcacaaagtt ttgatgaaca aatgggaact gactgttaaa gtacaagaga
    53641 tatttatgtt tagttcctga accgaccaat gaccatccga tagctggatc attttcaaaa
    53701 cgaaggtagc gtttcaagtc tggattttca gggtcttgga ttttatttgt atggtcaatg
    53761 tcaatcaagt tagcatagaa gtgaaaaaca cgttcaaaaa ttggaatttc acgagtagca
    53821 tagaattgac cactttcagt aaattctccc aaagtccaac catgacctaa ttgattgatg
    53881 tacttttcat aaatagcttt attggtcgca tttgcttcta ctgttacaga agaatccatg
    53941 ctacttgcct tttcttgcaa ctctttagta tcgtaatact caatgtagcc catacgctca
    54001 aacacagtat tttcatagtt atcacgttta tcagccgttg tcgcaatttt attatagtta
    54061 ggatcctgct tgaaaatcaa ttttcgagga accaaggtat agataatcgt gtaggtcaaa
    54121 gtcgttacta agaaaatcga aaccaatgac cgcaaaacac gcataaaaat atattttttc
    54181 atattatttc ctttaaaaat cccaaaagaa ccttctcctc atggagagaa agttctatta
    54241 gaaattattt acttcacatg acttgccaat tctttttgag ctttctcatt tgattcagct
    54301 ttttctttca accatttttc acgagctttt tcatactctt ccttagtcac cgctttatct
    54361 tgtaatttca aatatttgaa gtaaacatct gaccccttag agcctgtttg cgcagaagct
    54421 ccagtaaatg gaacaattcg tgaaagcact ggtgctgcac cagaagaagc catagcagga
    54481 ataaagagtg aactatctgt caaccatgct tgagccgctg catatttttc ataacggaca
    54541 ttcaagtcgc ttgtctcttt ggcagcttca tcaactaatt tatcgtattc tttcaaacca
    54601 acttgaacta ctgaagggct atttggatta tcaaatccta aatatgtttt tgtagtttca
    54661 ctgctagttg tttttaaaat atccaggtaa gtagatgggt cttgatagtc tggcccccat
    54721 gaaactcctc ccgatacatc ccaatcctca gatgaagcat tggcagcata gtaagtaata
    54781 ttaaggaatt catcacttgt catttgttga atatcaacaa cgacattttc aacaccaaga
    54841 actgtttcta cagattgttt aaaggactga atacgagata tatagttttt tgatgcttgg
    54901 tctactggaa cgtccagatg aataggaaac tgaacgccgt ctgcttctaa agctttctta
    54961 gctttcgcaa actctgcctt ggccttgtca gcattgaata aaccatcctg cccatcagct
    55021 aaattcacac ctttccactc atcaccataa gcaggaagtt gagcagcgac taaatcacca
    55081 aaggtcttct caccagctga aacaaagtct ggttttacaa ataaattacg aactgctaaa
    55141 gctgctccat ctttaccatt gatttgagct gagtaagctg agcgatcaag agcaaaattc
    55201 aaggcttgac ggaaatcttt gttaagcaat gccttcttag tagctacttt ctctgaatct
    55261 gtagttttag aagtatagtt gtaactttgg cgatcaatat tcacacccag accagcaatc
    55321 ccagagcctg attgtgtgta atagatattg tccttgtatt cttctgcaac cttagaatag
    55381 ttggagctgg tagggtaaag acgggcataa ctataggctc cactagtgaa gttacgctct
    55441 agcgactcct gatctgatcc atcatagtaa gctagattga tagtatctag gtggacattt
    55501 tctttatccc aatattgctc attttttaca aactctacag aagattttgc agtcaaccct
    55561 ttcaacaaga atggaccatt ataaagcaag gatgtcggat ctgttggttt agcaaaatcg
    55621 cttccttttg atgtttcgaa ttcttcattc agaggccaga aaatagaata ggtcaactta
    55681 gagttccaga acggttcagg ctggttcaaa gtgtattgta acgtataatc atcaaccgcc
    55741 ttgacaccaa ctgttgaaaa atctgttgaa gttcctgata gataatctgc caagccttta
    55801 accgaatttt cagctaaata catagcttct gattttttat ctgctgcgtg ttttaaaccg
    55861 ttcacgaaat ctttagccgt cacctctgca tattcttctc catcagaggt aaaccattta
    55921 acccctttac gaatcttata agtgtaggtc aaaccatcct tagagacttc ccaatcctct
    55981 gcaactgcag gagcaagatt accgtaatta tcgttagtga ataaaccatc aatcccattt
    56041 gaagtcacta ctgttgtact atttttactt gaaatcaggt agtccaaggt ttctgggtct
    56101 gctgtataaa catagccata agctttaggg gctgatgaat cagatgattt tgaagaactg
    56161 catgctgcaa gtacacctgc tgctaataaa acaagacctg ctgtagcaaa tacacgattt
    56221 tttttcattt tctactcctc tgtttatgtg aattatagat tgacaaccat tatatcacat
    56281 tatccattaa aaatcaaaca aattttcaga atatttaggc ttgttggcac aaatttttca
    56341 ttttttttga atatatgatt caaattgtcg ttcgaagtgt caaagactac agtgaaaata
    56401 ggaaatttga cgcagaaact ttggagctta ggaagacata cagtaaaatg aaatacggac
    56461 ggaacaatgt gattttggaa ttcaaattaa attataacaa tattgtagaa gtatcattct
    56521 agtattcaag attcagttta ctatgtcttt tcacaccaac cttattccga attcaattac
    56581 tttcgtgatt tacacatata gattaagact atcttttacc caaatcattc atacctctct
    56641 caactagatg taacttacaa aacccctgac ctcatgagcc actttcttcc tcctcatgag
    56701 gtcagtttta ctttctgctg ttccagtatc gtttttcctc gctagatttc ctcaaaaggg
    56761 cagactcctc ccttggtgcg tcacacgatt ttttcatctc gactgttctt taatgcatca
    56821 ttaacgacgc ttttcttcca ggtggttcat aaggaacagg aagattcagg ttgacttttc
    56881 taatcctaga ataaagtgct gaaaacaatt cggaataggc atagagacta gacaatttga
    56941 ggagctgctt gcgtcctgtt cgaacacagt ttcctaccac gtgaagaaaa agatggtgga
    57001 agcgtttgat tgttaaagtt tggaagtcac ctccagctag atgtttgaga aaaagataga
    57061 gattgtaggc gatacagctc atcatcatac gaacttcgtt tttgattaag gttgaactat
    57121 ccgttttatc gccaaaaaat ccctccttca tctccttgat gaaattctcg gcttgaccac
    57181 gtccacgata aagctgaaac tggtcttggc ttgttccact cgtcatattt gtaacgagag
    57241 aaataatatc gtagaacaag tttccttctt ttcgttcaga gaactggcag acacgacgct
    57301 tgtgcgacca agatcctgct tgatagagag tttctgagta ggcggagtgg ggcaagatgg
    57361 ttaagtcctc atcctgtggg caagggaggg aaaggtctcc aagacggctc agaacagtat
    57421 ttttcttgag ttttatgagg tagtattgcc ctgttttttc aattaaatcg tataattttg
    57481 gggtcgcaaa gccactatcc attcgaaaga gaagttgatt aaaccgttct aaaacaggtg
    57541 tgataaagct gtctgcctct tcagaacaat aacgattacc aggacgaagc tgggcattga
    57601 aacaataacc tgtcttcccc tcgaaagcat aaagaggatg atagccatga gcacgatagt
    57661 gggcgttata agcaacacct tcttgcttgc cataagttgt gaaatgggta gaatcgatat
    57721 ctacaatgag ttggtttagc tggtgaaact gtaaaaagaa ttcgaccaat tcaaggttga
    57781 ggcatcgcaa actatggact gtttcctcgt cagttctgga aagaaaacgg gataaggttg
    57841 gctgtgaagc aagctgccct ccttccaaca attttggaaa gtaggcatca gctgacaatt
    57901 ctttacaagc atagtccgtt ccatagcctg ttaacagttg aaagaggaac tggacaagga
    57961 tatctgaatc cgaataacga cagtagcggc gttggtcatt cgttactaaa tacttagaaa
    58021 tcagctcttt tagtttcaac tgggaaaaaa gttcctgaaa aaagataaga ccaccatact
    58081 gggttaaatg acctccatcg aaagatagtt ggtaaaaaga cttgttttgg aagtgatgat
    58141 ttggtaaact gttcatgtga gtttcctttc tttttgtgtt tttttctaca cttataccat
    58201 aaaggggaaa ctcttttttg tctagtaaaa aacacccatt gggtgaaaaa agaaaccatc
    58261 caggatctaa gctaaggcaa ggattctgga tggtttttaa attaggggtg aataattggg
    58321 gttttatact ttaaaatttc tcgctacctt atccactata tgctcctcgc tatcacgttt
    58381 ctattcatag cctacgattt cactattgct ttctctgaca attcttattt cctgcgtcag
    58441 acttaaaacg atctatcccc agaccatttt aatccgctac ctcacgatag tcaggcttgg
    58501 ggagcgctat tgtattcacc ggtagtggat ccctacagag gacttacacc tcagatgcac
    58561 gacatgccca tcgtataaaa aatctcctac ccaaggtaga agatttcaaa cttataaaac
    58621 ttaatccgtc atgtccgata ccaacattcg atgctccaat ggaatactgc acataactag
    58681 caagaaaata aagcctgact gaatccagaa gagagccaag tcaaaaattc cgtgcacagc
    58741 aaccactgta aggaaagata gataaaggcc gataatcgga cgtttccccg actcctgact
    58801 catatccatc atcaagcgaa caggagcaac agaagacaga actaataaaa tggtacccac
    58861 aattccgtaa ctcagaatcg tatcaatata aagactgtgg gcatgttcat gataaggagc
    58921 atgtatccga ggataagagt gcatataggt caatggccct tcaccccaaa aaggattttg
    58981 cttaaacaag gccatcccag catcccagat agaaatgcgt tcttccatag aagagtctaa
    59041 agtacccatt cgaactccca aatcactaga aaagaggaaa ctcaaaccaa tcgcgaagac
    59101 cccaatacta agccaaaagg ccttccagtt tttaatagtc gtaaagagat agataattgc
    59161 tccagcgata atagcaggaa aggcagttcg attttgagta aagttcaaac caaagagatt
    59221 aacaaagcct gcaatcacac agaatacttt caaccaattc aacttggtcg ttgtaaacag
    59281 atagaaagca atcataatac agaaacaaca aataattcca taataattag gattaaagaa
    59341 ggtcacttct gcccggttct gatgccacac ctgcatattg ggggaaagaa aagcataatt
    59401 aaatttcttc acaatttgga aatgttctaa actggcaaaa gcagctgaca agacactacc
    59461 aaacaagacg aactgcaaaa tcaatcgaaa gaatttatgg gataaaatcg actgatagtg
    59521 caaaaagaaa atagtaaata gaaacattcc tactgaagcc acaagaccca tccaattttg
    59581 tgcaagaatg gatataacag tactatagcc aagaaaaaga agcagcatcg aatgctcccc
    59641 cattttctga agaatacttt tcatgtctcc tgtaaaaatc agactgataa tatataaaca
    59701 gaatacaact acaaaaagat aaaagggtaa aaagatactc aggataattc ccaataaaat
    59761 cagctcttta ctagacaacc ccttcagctt ttcaataaag cctattgatt tcaaaatgaa
    59821 tcctttctct ccaaatcagc tgattcagat aatagtaagc tatcctatat tgtaccactt
    59881 ttttagcaat ttgaaaacaa aggaaacgtt ttccaaaata aaaaccctat tttatccacc
    59941 atatcaaggc ttcaaaatgt tacttcaact ccattctcaa ttacccgata agtctgattt
    60001 tgcaagtcaa tttctgctac tgctgttacg gacttatctt tattttgacg tttgattaca
    60061 atgctgtgag ctgttggtgt ctctatctca gtagtccctt ctagatcaaa ggcttctgaa
    60121 cggttacgga aagaaaatag attgagaagg gccttcacaa caggtcgttg cacttctttt
    60181 gctatttcct cgttgctata gtaatgacga ttaatatttc gaccttcttt agtttcttct
    60241 aataatttca agtcattctt gcctgctaat agacccacat agtaaacctg aggaatacct
    60301 ggggcaaaag cttgaattag acgagcgaga aaatacttga catcatcatc tccaagcgct
    60361 gaatagtagg ttgaattgat ttggtagata tctaagttgt tatactcggc actagagtac
    60421 ttacgtttga cattggctcc aaccttatag agttcatttg aagcatagtc aatctcctca
    60481 tcggtcagga tatccttgac atctactact ccaatcccat catgggtatc tagcgtcgta
    60541 aattgcttca tcgggctcat ctttaaccac ttagccaaac gctctgttct ggaactgtaa
    60601 agagtataaa gtgtcaccat tggaagagca aaatcataaa catagtaatc atggtctgct
    60661 attttaaact gaatcgaata gtgttcatga atctcaggta aaagctctgt cccatactca
    60721 gcagcgatat ctcgaacttt gtccaataaa tcccaaatat ctggttccac aaagaaatca
    60781 ttagtatcca atttcttcac tgcataagca aaggcatcta gacgaatcaa atcacaccca
    60841 ttacttgcca agtgctgaat ggtcttacgg ataaattcca tagttacttc tttggtcaca
    60901 tcaagatcaa tctgctcctc accaaaggta ttccacaaat gttccactga accatcttca
    60961 aacacaatct cttgctttgg tgcacgatcc ttacgcttgt aaattaaatc tacatcagac
    61021 tgtgtcggac ggttttctgg ccaaaactta tcccagttta aaaagagagc tttaaattca
    61081 ctggcttcat gtttttcttg atagtcctta taatacttgg attgacgaga aatatgatta
    61141 atcataaaat caaacataag ataatatttc tcacctaaac gcttaacatc ctcccaatca
    61201 ccaaaagctg agtccacttc gtcgtagtca actggcgcaa atccacgatc acctgttgat
    61261 gggaaaaatg gtaaaaggtg aactcctcca atagcatctc caaaatgctc ttccaaatta
    61321 tcatataagt ctttaagatt atttccaagg ctatcagaat aggtaatcaa catggtttta
    61381 ttttgaatcg gcatcattac tctccttttt ctaattgaag ccaagtctca tatgatctgg
    61441 cttcgtaaat caaattcatt ttaaatctct atttatcatc aaactcgtac taatatagac
    61501 tgtgataaac aaagtactac tttcttgttt tctacataga attatcaaca agctgaactc
    61561 ttcctctgtg tcaaagacta tagattccat gagctcttct tatactcttc gaaaatctct
    61621 tcaaaccacg tcagcttcac cttaccgtag gtatggttac tgacttcgtc agtttcatcc
    61681 acaacctcaa aacagtgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt
    61741 ttcattgagt attacttcac tgccccgttg ctcattcctg aaatgatatg gcgttggaag
    61801 aagagataga caatggtgat actgataatg ccgaccacgt aagaggcaaa gcttggtccg
    61861 tagtcgttga aatattggcc tgcgtagttg tattggaaca aaggcagagt ccacattttg
    61921 gaatcccggt tcaagacaag gagtggcaac atgaagtcat tccagaacca aagggcattg
    61981 atgatcatgg ttgtcgcatg catcggtttc atcattggga agatgatgcg gaaataggtt
    62041 gtaaattgat tagccccatc gatctctgct gcttcatcca gactttctgg aatcgagatt
    62101 ttgatatagc caacatagag aaagagggtc tgtggaatcg cataggtcaa gtagagcaag
    62161 atcaaaccaa aggtattagc caaaccgagt ttactcatca taaccgtaat cggaatcatg
    62221 atgacttgga aaggtacgaa gattccgagg attaagaggg tatacatgat ggtaaagact
    62281 tttcttttac tcatattgcg agcgatggag taggctgcca tagggataaa gatcattact
    62341 gcaagtaaag acaagacagt gatgacgaca gagttccaat aatagcctcc aatcccatca
    62401 gctaagagac ggctaaagtt gtcccatgtg aagttggttg gaaagccaaa gaaattatct
    62461 acaatatcct tagtgggttt gaaggaacta aagagggtag caaggagcgg cactaaaatc
    62521 agaaccgatc ctagaatcaa tagaatgtat ttgccaatca gggcttttct ttcatcttgt
    62581 ttcatcatgc ttctcctctt aaatttcaaa tttcttagat actctcaatt ggatgatcga
    62641 aatcactaca attaagagga acaagattac ggcaatggca ttggcataac cgaattggtt
    62701 gtttttaaag gcatagttat aaaccaagag cccaagtgag gttgtggcat tgtttggacc
    62761 accaccggtc atggcaaaga cttggtcaaa ggcagtcagc ccacctttta gggctaggat
    62821 aaagaccata gagacacttg gtagcaagta aggcaattca atgttccaga aaacttgctt
    62881 gctagtcgca ccatcaatcc ttgctgcctc tgtaatctca gttggaatag attgcaaacc
    62941 agctaggaag atgatgatgg gcatagccac cccttgccaa agaaggacaa agacagccgc
    63001 aaagattgct ccccacttag tccctaaaag actggtttgg agaaattcaa tatgaagggc
    63061 attcccaatc gctggaagac cgtagttgaa gacttgcttg aagatcaaag ccactgtcaa
    63121 accagataaa acagctggga agaagaacca agcacggaag aaggtttggc ctttgatttt
    63181 agagttcaag acacgcgcaa tgaagatccc gagtgcaatc tcaccaacca ccatggcaat
    63241 cgtaatgatt gcggtaaagc caatcgcatt catgaatttt ggatccatga agaggagctt
    63301 aaagttgttt aagccgacaa atttgtagtt gtaagtcaat cctgtccagt tggtaaaact
    63361 gtaaaaggct ccttgaaaca tcggcacata gaagaaaatt gcttgtaaca agagggggat
    63421 gaccacaaaa gcccatgccc aatatttttg taatactttt ttcatagtct ctctactcct
    63481 aatccacatc cgctttcatc gggttaaaga aggcattcaa atcattgacc atgccttgtt
    63541 tatcaccggt caagacatag ttcatggtca aggtatggaa gtctgcttca ctggtccagt
    63601 attgttgcaa ccagaccaag tgacgatccg taaaggcata ttcggtcata ccagcaagcg
    63661 gtgaatcttc tcctgcttgt ttgacccctt cgatcgctgt tggagatccg tccacatcgt
    63721 agtatttttg catgacttct ggacgggtca tatattccac aaaggcattg gcttcttttg
    63781 gatgtttggt ggtggctgag atagaccatg ccaagtctcc cgcaccaacg gttaagcttt
    63841 gtcctttttc ttttcctgga atcatgaagg ttccaatctt aaagttcggt ttttgttcat
    63901 taatcgctgt gatcgcccaa gacccatttg gtgtcatgag gacatcccca cgtgcgaagg
    63961 ctccgataac atcggtatag ccagcacctt cccagttctt ttgcttagag ccattgatgc
    64021 gaaggatgtc catgaccttg atatcatctt tcataatcgg atccgacaat ttaatggcat
    64081 ttggttgaga ataacgaagg tattgatttg cttcttttcc tccacctgtt gctgtcgcaa
    64141 aggctaattg attgtaacca ttgagtgtcc aagcatctgc acctgcaatt ccaaatgatg
    64201 tttgtccttt agcaacgata tctttgacta actgttcaaa ttcatcccag gtttcaggaa
    64261 ccttcaagcc cagttcttcg aatttatctt tgttgtagta aattccataa gcattagctg
    64321 taaaaggaac gttataaact ttttcgttta cagcatattt ttcagcgtag gcatttttca
    64381 cgcgtttcag gtagtctttg ttgctcaaat cttcaaaaac acctgctttt gcccattctt
    64441 gcagttcgat ggactgtggg taaatattga ccacatcagg cacatctcct gcgagaacgc
    64501 gtgtcttcaa tacttcacca gcatttggta cattgacgac tttgaccttg atcttagggt
    64561 tttccttctc aaaatcacga gtgatttctt ccaaggtttt ggtcatttct tttttctggt
    64621 tgaaatactc gatggtcact gtgccatccg cagatttacc atagttggag caagcgccga
    64681 gcccaaacaa agctaaacct gtagttgcaa gaagtccgat ttttttatac cattccatta
    64741 gaaagcctcc tttataaatt tatacaccct tattgaactg caccccaaaa gttagacaga
    64801 ataaatctaa cttttggggt cagtacatat catagttttc taaaaatata ctgtctactc
    64861 aaaaaatctc cttgggataa gataacagtt aagcccgcat acattagttc tgcacctgag
    64921 taaacttcgc cattttcctg taatttatat agtccctctt catccaaatc ttttaatttt
    64981 aaagttgttt ccatggtctc tacaacagat aaaacgcgaa cgtaggttac aatcgtttga
    65041 tttccgtaat taaattgtac agctgcttca ttggatgcag tatcaggatt aattagtcta
    65101 tactgctgtc ctaactgaac tactggtcgt aattctttat acaagttcac ctgattagca
    65161 atcgtagctt tctcttcatc tgataaattt gtcaaatcaa gctcatagcc caaatttccc
    65221 atcattgcta catggccacg tgtttctaat ggtgtcattc gtcccatctg atgattcggt
    65281 actgctgaca catgagcccc catagaaatg gttggataga gataggatga accgtattga
    65341 attggtaaac gtgcaatggc atcagtatta tcactagccc agacttgtgg gaaatagcgt
    65401 atcataccaa gatcatttcg tccaccacca ccagagcagg actcaaagag aatatggctg
    65461 tgcttctctg tcagataaga aacgagttcg taaagcccca gcatgtactg atgagattgc
    65521 atctgtgtct ctagataagt taatccattc cctagcttag tgatattgcg gttcatatcc
    65581 catttaatgt aatcaatctc atgataagat aggagttgat ctaagacact tttcaagtat
    65641 tctactacct gaggattggc aagattaagt actaattgat tccgagaata agtatgctca
    65701 taatcaggaa cctgaatagc ccagtcagga tgttgacgat acaaatcact atctacagaa
    65761 atcatttcgg gttctaacca aagtccaaac tgcaaacctc tttcatggat agctgaaatc
    65821 agactttcta gacttccacc cagtttttcc tcattaacaa cccaatcacc taaagcacga
    65881 ttatcatcaa aacgattgcc aaaccaacca tcatctaata caaaaagttc aatgccaact
    65941 ttcttagctt catctgctaa ctctaacagt ttttctctct gaaagtcaaa gtaagtagct
    66001 tcccagttat tgattagaat tggacgttct tttttagaaa attcacttag cataatgtgc
    66061 ttcagtacaa aattctgact ttcatgacta ataccagtta atccctgatc tgaatgagtc
    66121 actaaagcta ccggtgtttc aaagtattcc tcaggggcta acttccaaga aaagttttct
    66181 ggattaatgc caatagccac ccgaacttca ttcaattgat ttttttgaac aaaagcttca
    66241 aagttgccac tatacattag ttgaatagca aacacattcc cagcatcctc tgtgactcct
    66301 tgttcgcata gtagaagagc tggtgtttga gcatgaccag aagcacctcg gtttgaacta
    66361 atcgaaaaga ttccttgttc tacctgttga cgtctaacag tcttttcacg agcataagca
    66421 ccctgcagag ttgctatttc ataatctgca gctggaaaat cagccataaa agaaaaatct
    66481 ttatggatga caacttcctg attactatta ttatctaatt tactgtagct agtaatagtc
    66541 gcatcattat taaaagtagt ataatacaaa gtcagactaa gttgagcctt agaatcttct
    66601 aacattaaga caagagtctc tgtatcgtcc atgctatgtg gagaaggtaa gccctgtgga
    66661 ccattctgac cttttaaaat ctttgcttct acaaatcgaa agtctgttac ttcagttaca
    66721 ctatgctgaa cctgtatagt tggtttccta aaatctccta agccatgttg tccaaaaatc
    66781 tgtcgctgag tatctaaact aaaggttcga ttagtagccg ttggatttcc tgaaaaggca
    66841 tggtctcgtt cataaacact attggaacct ttatagttct taatagtctt tcctaaatgt
    66901 ttcaaaagta agtagccatt tcgattttca ataatcaaac ttagattttt actctcaaca
    66961 taaaatagat tattctctat cctaactccc atttacttca cctcatcact ttattgatta
    67021 tattttatca cctgaaatcg ctttccaaaa tagaaaaatg tctcaagaat atggtaaaat
    67081 gttaggtagg aggtagcaca tgttagtttt ttcagaatac cagactggaa caatcgacct
    67141 tgccctaagc ttttatggat atgaggaatg cacacctaat tactcttttg gtccagccat
    67201 tcgtgataca tacgtcctac attacattac taaaggacaa ggaaaatttc attacaagga
    67261 taaaattgtt gatttaaaag aaggagattt ctttctatta aaaccagagg aactaacctt
    67321 ttatcaagca gatagtaaag aaccttgggc ctactactgg ttaggaatca ctggagggaa
    67381 atcccctgat tattttgctc tttctcaaat ttctgatcaa tcctatctca tccaatctga
    67441 aacttgtcat acccagacta ctgcaaaact catctcagac attgtccgct tcgctcagat
    67501 tacaaaatca agtgaattag ctcaactcca tatcatggga caacttcatg aactgatgtt
    67561 tcatctggga actattgctc ccaatcagaa aaaaaagaat atttcatcaa cccaccaact
    67621 ctatcttgaa tgcaaacgat taattgatag ccactatcct caatcactta caattcaaga
    67681 tttagcaaaa gaactatccg ttcacagaag ctacttatca agcgtattca aagaatttaa
    67741 taccttatca cccaaagaat acctactcta cgttcgaatg caccgagcta gacaacttct
    67801 cgaaaatacc caagagtcca tcaaggtaat tgcatactcg gtaggttttt cagatccact
    67861 ccatttttcg aaagcttata aacaatactt taatcagact ccaagtcata caagaaaaga
    67921 atactctcaa taccaactag tgagaaaggc aacattatga aatcctacca agctgtctac
    67981 caaatcctat ctaaagaaac cgactatatc agcggagaaa aaatcgcaga aaaactatcc
    68041 ctaagccgaa catcaatttg gaaagctatc aagcgactag aacaagaagg cattgaaatt
    68101 gatagtatca aaaatagagg atataaacta atgaatggtg accttattct tccagagatt
    68161 ctagaagaaa atcttccaat taaagtcagc tttaaacccg aaacaaaatc aacacaacta
    68221 gatgcaaaag aagcaattga tttaggccat gaagcaaata ccctctatct agcttcctat
    68281 caaacagcag gccgaggacg ttttcaacgt tccttctact caccacaagg tggtatttat
    68341 atgacactcc atcttaaacc aaatctcccc tatgacaaat taccatccta cacactactt
    68401 gtagctggag ctgtctacaa agctattaag aacctaactt taatagatgt cgacataaaa
    68461 tgggtcaatg atatctatct aaacaatcat aaaattggag gaatccttac tgaagcaatg
    68521 acctctgtag aaactggctt agtcacagat atcattattg gagtaggtat caatttcact
    68581 attaaagact tccctcagga attaaaagaa aaagctgcca gcttatttaa agctacagct
    68641 cctataacaa ggaatgaatt gatcatagaa atctggcgtg ctttcttcga aacaccagca
    68701 gaagagctat tatacctata caaaaaacag tcattcattc taggaaaaga agtcactttc
    68761 acactacagc aaaaagacta caagggactt gctaaagaca tctcagaaaa tggaaaactt
    68821 ttagttcaat gtgataacgg aaaagaaatc tggctaaata gtggcgaaat ttctctcaat
    68881 agttggaagt aaaataacac aattataata taaggctcta taatatttgt agtgggtaaa
    68941 tccactatag atattatgga gcctattttt gtgtagaaaa aaagtcccat aagatttata
    69001 atgaaaagcg atcaaacaac tcattagaaa gattcatatg gaacaattac attttatcac
    69061 aaaactactc gatatcaaag acacaaatat ccaaattata gatgtcgtca atagggattc
    69121 acacaaagaa atcatcgcca aactggacta cgacgcacca tcttgccctg agtgcggaaa
    69181 ccaattgaag aaatatgact ttcaaaaacc ttctaaaatt ccttatcttg aaacgactgg
    69241 tatgcctact agaattctcc ttagaaaacg ccgtttcaag tgctatcact gttcaaaaat
    69301 gatggtcgct gaaacttcta tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca
    69361 aaaaattgcg caaaagttga ttgagaagat ttctatgacc gatattgctc atcagctggc
    69421 catttcaact tcaactgtta ttcgtaagct caatgatttt cactttaaac atgatttttc
    69481 ttgtcttcct gagattatgt cttgggatga gtatgctttt acaaagggaa agatgagctt
    69541 cattgcgcaa gattttaaca atctcaatat catcactgtt cttgagggta gaacacaagc
    69601 tatcattcga aatcactttc ttcactacga tagagctgtc cgatgtcgcg tcaaaatcat
    69661 tactatggat atgtttagcc cttactatga cttggctaaa cagcttcgct ttcaaatttc
    69721 taggctcagg ctgaaacagt ctcccagact gtttcactcc cgaatgctaa aatcgttctt
    69781 gatcgctttc acattgtaca acatcttagc cgtgctatga gtcgtgtgcg tgttcaaatc
    69841 atgaatcagt ttcatcgaaa atcccatgaa tacaaggcta tcaagcgcta ctggaaactc
    69901 attcaacagg atagtcgtaa actcagcgat aaacattttt atcgccctac ttttcgtatg
    69961 catttaacca ataaagagat tttagacaag cttttgagct attcacaaga cttgaaacac
    70021 cactatcagc tctatcaact cttgctgttt cactttcaga ataaggaacc agagaaattt
    70081 ttcggactta ttgaggacaa tcttaagcag gttcatccta tttttcagac tgtctttaaa
    70141 accttcctca aagataaaga aaagattgtc aacgcccttc aactacacta ttctaatgcc
    70201 aaactggaag cgaccaataa tctcatcaaa cttatcaagc gcaatgcctt tggttttcgg
    70261 aactttgaaa acttcaaaaa acggattttc atcgctctga acatcaaaaa agaaaggacg
    70321 aaatttgtcc tttctcgagc ttagcttttc ttcaacccac tacagttgac aaagagcctt
    70381 aagtttacgg atctgaagtt ttattgtctc taaaaacaaa aaagagagtt acaaactctc
    70441 attaaaacgg agaataaggg attcgaaccc ttgcgccagt tacccgacct aacgatttag
    70501 caaaccgtcc tcttcagcct cttgagtaat tctccaatta atgggcacga gtggactcga
    70561 accaccgacc tcacgcttat caggcgtgcg ctctaaccac ctgagctacg cgcccaagtt
    70621 aaaaaacttg gtaatttgaa caaagttcaa agcgggtgac gagaatcgaa ctcgcgacaa
    70681 cagcttggaa ggctgtagtt ttaccactaa actacacccg cataaatact atcaataaaa
    70741 tggcgcgaga cggaatcgaa ccgccgacac atggagcttc aatccattgc tctaccaact
    70801 gagctaccga gccttattgc gggagcagga tttgaaccta cgaccttcgg gttatgagcc
    70861 cgacgagcta ccgagctgct ccatcccgcg ttaatataaa aggaggatgt gggattcgaa
    70921 cccacgcacg cttttacacg cctgacggtt ttcaagaccg ttcccttcag ccggacttgg
    70981 gtaatcctcc aaaatagttt atacgggaac aagcccgtgt cctcttagtg aacagataat
    71041 attccaatcc cctagtaatg gactaaacac tatgggcacg agtggactcg aaccaccgac
    71101 ctcacgctta tcaggcgtgc gctctaacca cctgagctac gcgcccaagt caaaaacttg
    71161 gtacaaagaa caaagttcaa agcgggtgac gagaatcgaa ctcgcgacaa cagcttggaa
    71221 ggctgtagtt ttaccactaa actacacccg ctaaa
//
LOCUS       DAVMJI010000008        66725 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.008, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000008 DAVMJI010000000
VERSION     DAVMJI010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66725
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.008"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(183..1934)
                     /locus_tag="VYR58_000602"
     CDS             complement(183..1934)
                     /locus_tag="VYR58_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621805.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            complement(1936..3660)
                     /locus_tag="VYR58_000603"
     CDS             complement(1936..3660)
                     /locus_tag="VYR58_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621806.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VLVAILTIVIVGLSRLVNPFYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            complement(3718..4656)
                     /gene="msrB"
                     /locus_tag="VYR58_000604"
     CDS             complement(3718..4656)
                     /gene="msrB"
                     /locus_tag="VYR58_000604"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV3621807.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4798..4875)
                     /locus_tag="VYR58_000605"
                     /pseudo
     CDS             complement(4798..4875)
                     /locus_tag="VYR58_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4951..5820)
                     /locus_tag="VYR58_000606"
     CDS             complement(4951..5820)
                     /locus_tag="VYR58_000606"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV3621808.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(5822..7108)
                     /locus_tag="VYR58_000607"
     CDS             complement(5822..7108)
                     /locus_tag="VYR58_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV3621809.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7259..7996)
                     /gene="mecA"
                     /locus_tag="VYR58_000608"
     CDS             complement(7259..7996)
                     /gene="mecA"
                     /locus_tag="VYR58_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV3621810.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8196..9230)
                     /locus_tag="VYR58_000609"
     CDS             complement(8196..9230)
                     /locus_tag="VYR58_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV3621811.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9259..10692)
                     /locus_tag="VYR58_000610"
     CDS             complement(9259..10692)
                     /locus_tag="VYR58_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV3621812.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(10708..11694)
                     /locus_tag="VYR58_000611"
     CDS             complement(10708..11694)
                     /locus_tag="VYR58_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV3621813.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11696..12799)
                     /locus_tag="VYR58_000612"
     CDS             complement(11696..12799)
                     /locus_tag="VYR58_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV3621814.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTNVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12789..13634)
                     /locus_tag="VYR58_000613"
     CDS             complement(12789..13634)
                     /locus_tag="VYR58_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV3621815.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13913..15187)
                     /gene="psr"
                     /locus_tag="VYR58_000614"
     CDS             complement(13913..15187)
                     /gene="psr"
                     /locus_tag="VYR58_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV3621816.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15184..16032)
                     /gene="pheA"
                     /locus_tag="VYR58_000615"
     CDS             complement(15184..16032)
                     /gene="pheA"
                     /locus_tag="VYR58_000615"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV3621817.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(16029..16505)
                     /locus_tag="VYR58_000616"
     CDS             complement(16029..16505)
                     /locus_tag="VYR58_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV3621818.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16498..17781)
                     /gene="aroA"
                     /locus_tag="VYR58_000617"
     CDS             complement(16498..17781)
                     /gene="aroA"
                     /locus_tag="VYR58_000617"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV3621819.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17873..18211)
                     /locus_tag="VYR58_000618"
     CDS             complement(17873..18211)
                     /locus_tag="VYR58_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV3621820.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18222..19325)
                     /locus_tag="VYR58_000619"
     CDS             complement(18222..19325)
                     /locus_tag="VYR58_000619"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV3621821.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEYLITENTDYTVVIK"
     gene            complement(19335..20501)
                     /gene="aroC"
                     /locus_tag="VYR58_000620"
     CDS             complement(19335..20501)
                     /gene="aroC"
                     /locus_tag="VYR58_000620"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV3621822.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20511..21578)
                     /locus_tag="VYR58_000621"
     CDS             complement(20511..21578)
                     /locus_tag="VYR58_000621"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV3621823.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21597..22451)
                     /locus_tag="VYR58_000622"
     CDS             complement(21597..22451)
                     /locus_tag="VYR58_000622"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV3621824.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(22441..23118)
                     /locus_tag="VYR58_000623"
     CDS             complement(22441..23118)
                     /locus_tag="VYR58_000623"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV3621825.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23115..24278)
                     /locus_tag="VYR58_000624"
     CDS             complement(23115..24278)
                     /locus_tag="VYR58_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV3621826.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHCFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24963..26597)
                     /locus_tag="VYR58_000625"
     CDS             complement(24963..26597)
                     /locus_tag="VYR58_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621827.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(26578..27327)
                     /locus_tag="VYR58_000626"
     CDS             complement(26578..27327)
                     /locus_tag="VYR58_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621828.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            27506..28960
                     /locus_tag="VYR58_000627"
     CDS             27506..28960
                     /locus_tag="VYR58_000627"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV3621829.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(29050..31668)
                     /gene="alaS"
                     /locus_tag="VYR58_000628"
     CDS             complement(29050..31668)
                     /gene="alaS"
                     /locus_tag="VYR58_000628"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV3621830.1"
                     /translation="MKQLSSAQVRQMWLDFWATKAHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAAILKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31690..32175)
                     /locus_tag="VYR58_000629"
     CDS             complement(31690..32175)
                     /locus_tag="VYR58_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV3621831.1"
                     /translation="MKTFLVKQKFRLGGERFAIKNDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32450..32689)
                     /locus_tag="VYR58_000630"
     CDS             complement(32450..32689)
                     /locus_tag="VYR58_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621832.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(32950..34020)
                     /locus_tag="VYR58_000631"
     CDS             complement(32950..34020)
                     /locus_tag="VYR58_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV3621833.1"
                     /translation="MKKIYSFLAEIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(34017..34790)
                     /locus_tag="VYR58_000632"
     CDS             complement(34017..34790)
                     /locus_tag="VYR58_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3621834.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34787..35593)
                     /locus_tag="VYR58_000633"
     CDS             complement(34787..35593)
                     /locus_tag="VYR58_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3621835.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35574..36731)
                     /locus_tag="VYR58_000634"
     CDS             complement(35574..36731)
                     /locus_tag="VYR58_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3621836.1"
                     /translation="MKKSIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRNIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36892..37797)
                     /gene="murB"
                     /locus_tag="VYR58_000635"
     CDS             complement(36892..37797)
                     /gene="murB"
                     /locus_tag="VYR58_000635"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV3621837.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(37909..38661)
                     /locus_tag="VYR58_000636"
     CDS             complement(37909..38661)
                     /locus_tag="VYR58_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV3621838.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38671..39402)
                     /gene="budA"
                     /locus_tag="VYR58_000637"
     CDS             complement(38671..39402)
                     /gene="budA"
                     /locus_tag="VYR58_000637"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV3621839.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIGEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39544..40815
                     /locus_tag="VYR58_000638"
     CDS             39544..40815
                     /locus_tag="VYR58_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV3621840.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40835..41650)
                     /locus_tag="VYR58_000639"
     CDS             complement(40835..41650)
                     /locus_tag="VYR58_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV3621841.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(41807..42460)
                     /gene="phoU"
                     /locus_tag="VYR58_000640"
     CDS             complement(41807..42460)
                     /gene="phoU"
                     /locus_tag="VYR58_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV3621842.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42472..43230)
                     /gene="pstB"
                     /locus_tag="VYR58_000641"
     CDS             complement(42472..43230)
                     /gene="pstB"
                     /locus_tag="VYR58_000641"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV3621843.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEIIALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43243..44046)
                     /gene="pstB"
                     /locus_tag="VYR58_000642"
     CDS             complement(43243..44046)
                     /gene="pstB"
                     /locus_tag="VYR58_000642"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV3621844.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(44057..44941)
                     /gene="pstA"
                     /locus_tag="VYR58_000643"
     CDS             complement(44057..44941)
                     /gene="pstA"
                     /locus_tag="VYR58_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV3621845.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44931..45848)
                     /gene="pstC"
                     /locus_tag="VYR58_000644"
     CDS             complement(44931..45848)
                     /gene="pstC"
                     /locus_tag="VYR58_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV3621846.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGIWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45848..46726)
                     /gene="pstS"
                     /locus_tag="VYR58_000645"
     CDS             complement(45848..46726)
                     /gene="pstS"
                     /locus_tag="VYR58_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV3621847.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47300..48604)
                     /locus_tag="VYR58_000646"
     CDS             complement(47300..48604)
                     /locus_tag="VYR58_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV3621848.1"
                     /translation="MQFPEGFVEKYKEILGDEARNFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKSSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48605..49378)
                     /locus_tag="VYR58_000647"
     CDS             complement(48605..49378)
                     /locus_tag="VYR58_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV3621849.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYLEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49368..49646)
                     /locus_tag="VYR58_000648"
     CDS             complement(49368..49646)
                     /locus_tag="VYR58_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV3621850.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(49646..50047)
                     /locus_tag="VYR58_000649"
     CDS             complement(49646..50047)
                     /locus_tag="VYR58_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV3621851.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50257..50874)
                     /locus_tag="VYR58_000650"
     CDS             complement(50257..50874)
                     /locus_tag="VYR58_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV3621852.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(50864..51637)
                     /locus_tag="VYR58_000651"
     CDS             complement(50864..51637)
                     /locus_tag="VYR58_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV3621853.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRGIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51648..52385)
                     /locus_tag="VYR58_000652"
     CDS             complement(51648..52385)
                     /locus_tag="VYR58_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV3621854.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSVVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52390..53520)
                     /locus_tag="VYR58_000653"
     CDS             complement(52390..53520)
                     /locus_tag="VYR58_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV3621855.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53604..53993)
                     /locus_tag="VYR58_000654"
     CDS             complement(53604..53993)
                     /locus_tag="VYR58_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV3621856.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(54009..54392)
                     /locus_tag="VYR58_000655"
     CDS             complement(54009..54392)
                     /locus_tag="VYR58_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV3621857.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54393..55181)
                     /locus_tag="VYR58_000656"
     CDS             complement(54393..55181)
                     /locus_tag="VYR58_000656"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV3621858.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGVLVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55174..56109)
                     /locus_tag="VYR58_000657"
     CDS             complement(55174..56109)
                     /locus_tag="VYR58_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV3621859.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56239..56415)
                     /locus_tag="VYR58_000658"
     CDS             complement(56239..56415)
                     /locus_tag="VYR58_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV3621860.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56555..57262)
                     /locus_tag="VYR58_000659"
     CDS             complement(56555..57262)
                     /locus_tag="VYR58_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV3621861.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESNLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57413..58441
                     /gene="queA"
                     /locus_tag="VYR58_000660"
     CDS             57413..58441
                     /gene="queA"
                     /locus_tag="VYR58_000660"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV3621862.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(59102..60229)
                     /locus_tag="VYR58_000661"
     CDS             complement(59102..60229)
                     /locus_tag="VYR58_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV3621863.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFTTEYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(60944..61495)
                     /locus_tag="VYR58_000662"
     CDS             complement(60944..61495)
                     /locus_tag="VYR58_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3621864.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61893..62717)
                     /gene="nadE"
                     /locus_tag="VYR58_000663"
     CDS             complement(61893..62717)
                     /gene="nadE"
                     /locus_tag="VYR58_000663"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV3621865.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRSETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62714..64174)
                     /locus_tag="VYR58_000664"
     CDS             complement(62714..64174)
                     /locus_tag="VYR58_000664"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV3621866.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEGLRFSDSDIAYLELLGYHGAFLNYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64290..64778)
                     /locus_tag="VYR58_000665"
     CDS             complement(64290..64778)
                     /locus_tag="VYR58_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621867.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64768..64977)
                     /locus_tag="VYR58_000666"
     CDS             complement(64768..64977)
                     /locus_tag="VYR58_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3621868.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65362..66090)
                     /locus_tag="VYR58_000667"
     CDS             complement(65362..66090)
                     /locus_tag="VYR58_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621869.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     ETSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVILVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            complement(66106..66651)
                     /locus_tag="VYR58_000668"
     CDS             complement(66106..66651)
                     /locus_tag="VYR58_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3621870.1"
                     /translation="MIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTKPDILILDEP
                     TNGLDIESSQIVLAVLKKLALNENVGILISSHKLEDIEEICERVLFLESGLLTFQKVG
                     KDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEEGLRITMSGNIQSSELFKFFNENSI
                     KVVDFETKKETLKDIYLNRSK"
BASE COUNT        19906 a        15066 c        12407 g        19346 t
ORIGIN      
        1 aactgacttc gtcagtctta tctacaacct caaagctgtg ctttgagcaa cctacggcta
       61 gcttcctagt ttgctctttg attttcattg agtattacag tgaacaattt ttctagctat
      121 tgtaacaaaa aagtcactcg aaggcaactt ttttcgtcca taaactttca aaagagaatg
      181 gcttattcag aactaaaagc cgcagctttt tgcatttggt aatacttacc ctttctatcc
      241 atgagttctt gatggttacc atattcaaca atatcaccat ctactaagac aagaattaaa
      301 tccgcatcct gaatggttga caaacggtga gcaatgatga aacttgtgcg gcccttcatg
      361 agttttgcaa aggcatcctg taccagcact tctgtccgtg tatcaatgga agaagttgcc
      421 tcgtctaaga taagaatctt tggaatagcc agaaagactc gggctatggt caagagctga
      481 gcttggccga cagagagaga ttctccagca ttttccaact tggtatcgta tccctgtggc
      541 aactgttgga tgaaaaagtc tgcattagct gctttggcag cagcaattac ttgctctcga
      601 ctggcttcag gattgccaaa ggcaatatta tcatgaatgg tcccttgtgt gagccaggtt
      661 tcttgaagca ccataccaaa ctgctgtctc aatgatactc gtgtataatc ataaatggat
      721 tgcccatcca gcaagatatc tcccgagcta atgggataaa aacgcataag gagattgata
      781 agagttgatt ttccagcacc tgtcggacca acgatggcta ccttactacc agctggaata
      841 tcgatagaca agtccttaat caaaattttt tcaggatggt agccaaaaga gacatgttta
      901 aaggaaatag ctcccttaac ttggtcactg gtcgtcaaga cttccttacc tgtttcagcc
      961 acttcagggc tatctaagac tccatagata cgctctacgc aagccagagc actttgcaac
     1021 tcagctagca ctgaagaaat atcgttaaag ggcttggtgt attgctgaac atagttcaaa
     1081 aaagtcacta aacgaccgac ggtcaaggct gaacccatca tgatacgata agctcctact
     1141 ccagctaaaa gggcataaat gagtgcattt acaaagcgag tcgaaggatt gaccgttgaa
     1201 gaataaaaga tggctgactg agaatagcct gagtagttgt catgagcctc acgcaatctt
     1261 tggataaatt ctgtttgagc attgaaggac tggattatag tctgctgact aagcgattct
     1321 tcaatcaact gagtctgaat tcccctcgtc tctgtttgct tctggaagag atgataggat
     1381 ttcttggcaa taaagcgtga aatcaccatg gacagtggcg tcaacagcaa gactaagaga
     1441 gtcatgagga gatgaatttg gagcatggct agaatactga ccaaaatcat caaaacacca
     1501 atgaaaaatt ggttaaaaat catggtcaag ccagctgcca actgttcgat gtccgtggtt
     1561 acacgactaa ccatctctcc actaccttgc ctatctacaa aggcaatcgg taaacgatgg
     1621 agcttatgga tgattcgctc ccgtaaatct ctggtataag agaagattag acgattatag
     1681 aggagaggat tggcccattg taccagagta tttcctatta ccaccaagag catctggaga
     1741 aaaatctgcc aaaaaactgg tgatgaacca gccactagga cttggtcaat gacctgccca
     1801 atcagaatag gtaggtaaat tgataagcca acttgagcaa tagttcctag aaaggctagg
     1861 aaaaggagga aaggatggct tgctaaatct acggctaaac gtttgagcgt ctggtttaca
     1921 gtttgtcgtt tcattctagt cctcctttcc atgttgggat gcattgattt cacaatagac
     1981 ttggctggat ttcatcaagt catcgtgctt gccaacagct agcaactcac ctttttccaa
     2041 gaggagaatc tggtccgcca tctgtaaagt tgaggttcgt tgagagatca aaattaagct
     2101 cgtgtttgga aaattttctc taatagcttt caagagcttg gactctgtaa tggtatccag
     2161 tgccgaggtt gcatcatcta ggatgagaaa cggagcttgg cgcaagactg ctcgggcgat
     2221 agacaatctt tgtttttgtc cacctgagaa atttcgcccc cctgcctcaa ctagagcatc
     2281 caagagtcct tccttttcac tgacaaaatc cttagcttgc gcaatctcca aggcctgcca
     2341 gagttcctgg tcagatactt cttgattgaa acctagagtc aagttggaac gaatggttcc
     2401 tttaaagagt tcgacctttt gaggtacata ggcaatccaa gaccgccact gctccaaatt
     2461 aagaggacta cgtccatttt gataaaggtc aatgttcccc ttgtctactg gataaagtcc
     2521 aagtaagagt tgcaccaagc ttgatttacc agaaccagtt cccccgatga tacctagaat
     2581 ttgtccttga gtcatatcaa aggaaatgta tctcagagaa ggctgggccg catcaggata
     2641 ggtaaaagtc aattcttgga cttgtaaaac cttatctctg gtagcttgct tttgttctaa
     2701 ctctgaatgg atatcctctg gagcctcaac aaagacttcc tcgattcgct tgactgagat
     2761 ataggactgg ttgagggaat tgatcaacat ggctagcttg accaattcca ccaaaatctg
     2821 taagaggtaa ttgataagag caatgagagc accttgactg agcactcctc cttgaattga
     2881 aatatagcct tgccagataa taacgagaag agttccattg acaatcagat aggtcagagg
     2941 tgttaataaa ctagaccaga aacctgtctt ttcttgtaat ctagcataaa cttggttaag
     3001 ggtttgaaaa atctgtaact ctcgtttttc ttgaccaaaa gcacgaataa cccgcatccc
     3061 ttgcaattgc tggcgcgttt cctgaaccag ttggtccgtt ttctttctga gactactgta
     3121 gaaaggattg accaatcgag ataaccctac aatgacaatg gtcaaaatgg caaccaagac
     3181 taagaaccag aaagtcaact cagctgagat tcgataagcc ataaaaatgg caccaaaaac
     3241 gataatgggc gctcgtaaaa agagacgcag gaattgattg ataccagtct gaatctggta
     3301 ggtatccgaa gtcaagcgag taaccaaact agaagttgtc agacggtctc tgctgtcctt
     3361 tggcaaggaa agaatatgac gataaagatc gtttgtcaat tccttagcaa aacctactgc
     3421 tgcctttgct gagtaaaatt gagctatcaa ggccactaaa acgccaatta ctgcaaagat
     3481 aaggagcagg ccaatctgca tccagagatg accttgatct ccctgaggta aagattggtc
     3541 aacaatccca gcaatcacca tgggaaccaa gagctcaaaa acagcttcta acagcttgaa
     3601 caagggggct aaaattgatt ccttgatgta gggtttgaag taagataata ggtgtttcat
     3661 aaatcccttc tattcatatt ctagaaatga agaaagtggg aagccccact ctctgtttta
     3721 tttgtttaag taaggcaata gatagccata tcctgctttt tccatctcat ccttggccac
     3781 aaagcgtaaa gaagcagaat tgatacagta acggaggccg cctaactccc gcggtccatc
     3841 tgtgaaaaca tgacccaagt gagcactgcc tgaacgagaa cgaacttcaa ttcgctccat
     3901 tccatggctc agatccttgt aataatgaat caactctttg gaaatcggac ggctaaaact
     3961 tggccaacca caacctgaag caaacttatc cttggcaaaa aagagtggct cacctgtcgt
     4021 aatatctaca taaatcccct cttcaaaggt ttggtcatag gcattggtaa atggagcctc
     4081 tgtagcagct tcttgtgtga cacgataaga ctcttcagat agactggcct tcaacacctc
     4141 ttgactaggc ttttcatagt ttgctgcatc aatcaatggc ttatcagcat cggtcacatc
     4201 gatatgacag taacctgaag gattcttcct gagatagtct tggtggtagt cttcagccag
     4261 aatgtagtgg cgtaattgct ccacttctac tgcaatcttt cgacccagca tgcgttcctg
     4321 ctcctgcacc actgtgtaga tagctggcaa atctgcttca tcctgataat aaatcccagt
     4381 tcgatattgg cggccacggt cattcccttg ttgattgata gatagaggat cgataactcg
     4441 gaaataataa agtaaaatct ctctgagtga cacttccttc tcatcgtaaa tcacttggac
     4501 cgtttctgca tggtctgttt ccttgatcaa ctggtaattg gtcgtttcga cttgaccatt
     4561 agcgtagcca acactggttt ctagcactcc agaaatgcgt gaaaaatatt cctctaggcc
     4621 ccaaaaacaa ccacctgcta gataaatttc tgccatcttt atttctcctt tatcacgttt
     4681 ttaactaata ctcttcgaaa atctcttcaa accacgttag cgtcacctta ccgtatatat
     4741 gttactgacg tcgtcagttc tatctgcaac ctcaaaacag tgtcttgagc tgacttcgtc
     4801 agttctatcc acaacctcaa aacactgttt tgagcagcct gcggctagct tcctagtttg
     4861 ctctttgatt ttcattgagt ataaacttct tttcacaaaa aggatatgaa accctctggt
     4921 caagagtttc cccatcctat cttctattct ttattttgct tctacacgga caccttgggt
     4981 atcaactctc aagtcatgca gttttccttt gaaaggttgc ttttccaatt ctgccttaat
     5041 tgttggcatc ttgtcatgag aagccagaac cataactgtc ggcccagcac cagaaaggta
     5101 ggttgcatag gccccatttt ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa
     5161 gtcctgacga tagcgctcat ggaagaggtc tccctcgatt gcttgcccag cggtcaccat
     5221 gtctcctgcc aacaaggcag caaccgctac attggcgata gaacttgcag caacagcttc
     5281 cttataagac aattttttag gcaagacact acggctgtcg cgagtacgta attcatagtt
     5341 tggaatgtaa gctagaaaat cacactctgg aaagtctgct acgatagcag agacttgccc
     5401 ttcaacagaa cttgcaataa cgagattacc ataaatggct ggagccacat tgtcaggatg
     5461 cccttcaatc ttggtcgcta actgcaattt ttcatggtct gataagttga gttgacccag
     5521 ttggttggct agttcaatcc cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc
     5581 caaagggaca tcactggtca ttttcaagcg tcttggttgc aagtctggta caatttgcaa
     5641 agcgattttg agcaagagat tacgctcatc atgtggaatc catttgccaa tctggtgttc
     5701 aatcagccac tcatctcgtt cttcgcagac ctcaatttga agatacttgg ttacagctac
     5761 accgaccgag tcaaaacctg gcccgatatt ggcactggtt gcaggtacaa taatcttcat
     5821 cttattctcc tagcaccttg aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt
     5881 cagctgagac attttcaagc tgggctttat taatcttgtg tgtgatgata acgacacgcg
     5941 ccttgtcacc ctctttgcca tcttgaagga tttgcttaaa ggaaatatct tgagcattga
     6001 agatttcagc caacttcaag acctgacctt ttgagtctag agccaagatt gagaaatagt
     6061 agtttgcttt gacatcttca ggatttgcca agaccaagtc acggctatat tcgttgaagt
     6121 ctttgccaat agtaccatca ttcaaacgac gaacgatacg gacaatatca gctacaacac
     6181 ttgttgcagt tggtttttga cccgcacctg gtccgtagta catagactca ccaataccaa
     6241 tagattctac aaagacagcg ttcattacgc cattcacact agcaagtggg tgcgctttag
     6301 gtaggaaggt tggagtcact tctgcagcaa tacctgaaga agtttcctca atagaaccaa
     6361 ccaatttcac tacgtaacca agctcttgag ctacagctac gtcttctggt gtgatattgc
     6421 ggattccctt gtgggctaca tcatcaaagg caatcttcat gccaaaggca aattgactca
     6481 aaataaccat cttgtaggct gcatcaatcc catctacgtc attcgtcgga tcgctttctg
     6541 caaatcctag acgttgtgct tccgcaagag catcatcgta agaccagcct tcttccacca
     6601 tcttggtcac catgaagttg gaagttccgt tgactactcc aagcacgcgc gtaattttat
     6661 cagaagccaa ggaatttgct aaagtacgaa gaattggaat cccaccagca actgctgctt
     6721 cgtagtaaag tgctaccttg ttagcttgag cgatttctag caattctgcg ccatggacag
     6781 ctaaaaggtc cttgttagca gtaacaacgt gttttccagc ttccaaggca cgagtgataa
     6841 aggttttagc aggctcaata cgccccatca attccactac gatagtaata tcctggtctg
     6901 ataaaatatc atccacattg gttacaaagt taaagtcatt ccctgctgca agcaagcgat
     6961 ttttttcatc ttcatccttg accaatacct tagcaacttt gatatctgaa tgtgctgatt
     7021 gattgatttt tcctccattt tcctttagga ggaaaggcac accacttgca acggtaccaa
     7081 atcctagtaa agcaatttta actgtcatct ttatctcctc gaaattttct aatatagcca
     7141 ttataacaga attttgtgaa aattcctatt atagtaaatc actatttcag tataaaaaga
     7201 aaaaacgaat cagacgattc gctcttctta aaatctgaaa atagctttcc agaaaggatt
     7261 agccgatttt ttgcagattg agcactgcat cgtgactcat caagacttga ccatactctt
     7321 gtaagactga gcgactgata tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc
     7381 aagctggata tgggcttgga tgattttcaa tatccactaa aatggtcaaa taatagcgct
     7441 cgttcatttt gtagagttca gaagtttcca tttcaaaagt cactgtcttg gcaaaaacta
     7501 ccaagtcagc caacttagca aaagaaagga tgtagtagat gtaaggttct ttcttactct
     7561 cagcttcttg ttcagcctgc tcttgctctt cttccttggc ttcaacttgc tcaagagatt
     7621 gaatggcttc gatatcatcc ttggttttgt ctgcgatgct tttttccagg gttttgataa
     7681 attcatctgg agacatttga gccaattctt ccatatctgg caaatccgat aagtcttcaa
     7741 aatctagatt ttggtcaatc tttgacttgg tcacaaagac atctacctta tcaggttttg
     7801 gagtcacacg gaagctcaac atgcctgtat ccagaaagct atcaggcatc tctagttcat
     7861 ccaagatagc ataaaagaac tcttctgttt tttcttgagg aacgagaaag tcagcaatct
     7921 ccattccacg atccatcaaa tcctctaaag acatcgtgat ttttaaagtt gtatcactaa
     7981 tttgtttcat tttcattgct agtaacctca tactttcagt tctatctatt atactagatt
     8041 tttacgattt tatcaaaaga aggctcctct atacggatag attttcccta gggtctttct
     8101 ataggagact ccaaaagaaa atttctgcag acagatagaa aaagccttca aaatcagctc
     8161 ttagccgatt ttgaagacct tatacatcag aatacttata atttaaaggt tgctacacca
     8221 aggatagaac gatttaagtt tctgagaatt tgaagacttt gctcaaattt cttataacga
     8281 gtcactccgt actcttcaac aagaaggact gtatctcttt ccaaaagaga tgatacatcc
     8341 tgtaaatcta caaaatgcat tccttttaaa gcttcttgac tctgtttcaa tttatctagg
     8401 atagctttat ttgagctaac gatggtcaat tcctgtccag tatttttgta tgacaaaaca
     8461 tctgctaggt tagcaattgt tgtaatctct gttacaaaat caatttgata ctgagaaaaa
     8521 tcacctactc tattgattgt tggattaaag agataaacta acacatttcc catcacaacc
     8581 aaaatcacac aaaccactcc aataacaact aaacgaagaa tcagattttt cacatttaag
     8641 ccaagcgctg tttcaccatt tgcgttcaat tctttagagt tgatggtttc cagtttttca
     8701 attttcacat ttgcataggc atgtttaaat ttctcaatca acccatcaat ttttttctct
     8761 aacaagtcat tggcatcttt acttgatgtc aaaattttca caccaacccc tgcatcgtca
     8821 atcatatagt agacggtcaa ttttttccac caatagtcat tcgttgaatt tttcaaggtt
     8881 gtttctgtcg tgtctaattc actggcaatt tttttcaact cactgggttc tacatcattg
     8941 aaaagataag ctccattcaa attaccatca atcaatttcc cataaaaatc actataacca
     9001 ccaatttgat gattcaaaat cgttttggcc gactcttttg gaggagtgat tttatagata
     9061 agataagttg aataacttgt tgtatctttg acagtgtttt tattcctaac tgctttaatt
     9121 gtaaatggta cagcaatgag agcaaataaa gcgatgagag ctaaaatatt tgcttttcgc
     9181 tttttataaa gatttgcaaa caaatcagct actgaataat gttcaaacat gatttttttc
     9241 tcctttgttt agtagatact agttttcctt tgtaagcatt tttgctacaa atataatcac
     9301 aagaacaatt ccccagaatt gcattgtaaa taaattgaag aaactttctg aaaagctgct
     9361 tcttggcata aagaatagat tattcaagat gagtagggat aaagcaaata ggattgtcct
     9421 tgagcgatag gctacttgca gcatggctat aaataatacg ccgagtaaga aactaagcag
     9481 aaagactcca atcataccat agtcggtata caactccatg atataactac ttccgatacc
     9541 atgccctttc aagtattcct tgttcaagac aagataggat agattgtggg cataactatt
     9601 actatcaata gctagttcca cactattggt tgtatgttca aaggcttttc ctccgaaaat
     9661 ggctcccaaa ctcccccttg caaaataatc aagaacagga ccaaaagtaa aattacggaa
     9721 atctcggtaa gggaggctac tgttaaatag aaaacctcga gccagaacac caaaactagt
     9781 cccttgttta tagataaagt caagtaagat atcccagaaa cctgtatgag aaacttggac
     9841 attatcccgt acataattga gtactcccat cgctaacatg agaataggag aacctacaaa
     9901 aatcgctaac ttttctttaa acccaatcca ttttcctttt tcagtttgct cccgcataaa
     9961 gtaataaaca aaagcaaata aaatacttaa aataaaggga tttcgtgtcc caattgccaa
    10021 atgaatagta ttagctgcaa taaaggagac aagcactgct gtggcctgca atttctttgg
    10081 cttggttgcc agatacatac acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa
    10141 ataaggcagt ttactttcaa aatttgcata gtaggcatag taggaagtct gcaaacgata
    10201 caagagccgt tcaaataacc gaatgaaata gaaaggatag gttagaagaa aaactcctag
    10261 tgatacaaag cgtaaccgct tgatataaac ctcttttaga gaatttccta tatttgctac
    10321 ttttattttc ttcctagcta tgaagtaacg agccagaatg cctcctgtgg tcaagcccag
    10381 aatcgaaacc atgacaacta taaaggcaaa acgataggct attggatgat aggtatccaa
    10441 agcaccatcc ctaaaataat caatggtcgg tcttgatacc agaaatacaa aaatggttaa
    10501 atagaaaata aaatggatta agtaatactt gatatcattc caacaagcaa ttaagctact
    10561 aaccaacaag aacaataaag tagaaagtaa gctaacatta ttattattaa acagatacac
    10621 aattccactt actagcgtca aggcataact gactatggtc aaactaaata ataatcgttt
    10681 cccatcaatc acttggtcac ccccgttcta atgtaatttt ttagattttt caatattttt
    10741 cagtaataag aatcgatata aggaaatatt tatgaatagg gccaaagcac taattcttct
    10801 ccccttacgg aaaattggat tcctagaaat agcaaaggca tggcctttta aaaaacgatg
    10861 aatctgagaa taggcttcaa actgtttata ctgatcatct agcaacatct tatccagaat
    10921 aaagaagtgg gcataggcca atctgaaaaa agcgacctct ttcaagtcag gatagttttt
    10981 cacaacttca ttataaaact tttggtagat atcaatatag gctaaatcct tctctgcata
    11041 gggtttggtc gtaatactat cccctctatg gaaatagtaa taatagggtt tagtattaac
    11101 cacatacttc ttggccaact tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa
    11161 ccccttagga aaggataggg cagttgcaat ctgtctcttg attagcttat tgcaaatcgt
    11221 cccaggtatt ttttcaccta tgaggtattc ctttagaaat gtttgagaat cacagacaaa
    11281 atagtcatcc tgattggctg actgtgggct ttcatcatta gcatagacat tcatgacacc
    11341 acagcttgaa acatccgcat cttcttgaac taattgctca tataagctct gaatcatttc
    11401 tggatggata taatcatctg agtcaataaa aatcagataa tccccgtgag cctgcttcat
    11461 cccatcattt cgtgcttgcg acaatccttc gttcttttta tgaagcactg acaccctgtc
    11521 atcttgttca gcgattgaat cacacaagcg accactttca tctgttgcac catcatcaac
    11581 aagaataatt tccagatttt gataggtctg cttctgaatg gaagctatcg atttttctag
    11641 gtactgcgcc acattataga ctggcacaat cacactaatt aatgcagttt ccatgctact
    11701 cctctaatag tttttctact tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt
    11761 ggctagcctc atcgacatca aagtttgagg cagaagtcat gtaattagta atcgcctgag
    11821 ctgcctcttg attgctctca atgatttgtc caaatcgtcc ttcttgggat aattcctcag
    11881 cccctccaac gttcgtagag ataaaaggga gtcccagact caaggcctcc acatacactc
    11941 caggaaaacc ttcttgttta gacatagaca aaagaacttt cgtctgagat agatactgat
    12001 aaggattttt ttgataacca aggaaatgta catagtcctc aatcccatac tctttgactc
    12061 gttttttcag ttcctcttcc atatcaccag ccccgataaa atagagatga tagttttttc
    12121 cctcttggtg taataatcgt atcacttcca ctacacggtc agaaccctta ttttcctcaa
    12181 tccgtccgat agtacagata ctttgaggag caatctcgat atcgatcttc tcttgagatt
    12241 tttctagaat agtctgaaaa tcatatccat tgtagattgt ctgtaattta gaagtataat
    12301 ctggataaac ttccttgata gaattgctgg tcttttttga aatccctaca attgtattcg
    12361 cagcatccaa ctggcttcta tgtgattctc ttttagagct atccttaaga agttcttcaa
    12421 tacttccatg aatccaagat atcttcttga cttctcttct tttagagaac aacagtggtg
    12481 gattcataat ggtaaaagaa acttcaacat cataatcatc ttttacaagc aaacgacgag
    12541 ccagtcttgg aaaataaatt ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc
    12601 gataatcttg aagggatttt aaaatgcgta catgctttgg aacagattca tatcccttgt
    12661 caaagtgctc catttcaaga atatcaatat catacttttc tggatccaga tttgaaacaa
    12721 tggttgatag aatcttctct gcaccacctc caagagaaaa agaccacata aaaaataaga
    12781 tttttttctt agccaccata ttctcccttg tattctgtat aagacttatc catatcagcg
    12841 atgacagcat catgatgcgg tacctgcttg tctgctggtg gaggcgtcat ataatcccca
    12901 aaagcagttc tgagatagac atcatagccg attggaatag gcatctctgt tccttcaaat
    12961 ggcaagaaaa gattgtcttc aaaagatgtg attgggtact tgtttctcat gtagccagga
    13021 cctgagcata attctgtaat gccatcacaa tcagccaaat catacttagt catttctttc
    13081 tcagcttttt tccagatgcg ataacagaga gattttggag tcaaacccag taaaatgcga
    13141 cttccccatt tcatgagagc accatgcttt tctggaatag tttgcgcaca aaagagtgaa
    13201 taaatcaagg cccaacgaac ctgttttttc cgctcagctg gatttttcgg ataataatcc
    13261 aaaggcaaaa catccaaggc cagaccatgt ggcaaatcca aatcctgctg ataaggcttg
    13321 atacaggtgg tttccttgtc acgaatggta ataaaaagat tacgatcaac aaaatccttg
    13381 tgactctttg acaagaaata acgttcatct gcataacgag gccataattc tgctaatttc
    13441 tcataatctt tacgaggcat aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg
    13501 tttcgaaggg caccaatagc gcctccgcca cagagataac agagcaaatc atgttcttta
    13561 caaaaggcca caaaatattc agccatctcc agactacgag cctgaattgc ttttaaatca
    13621 gtcatattgt tcattattct ttctatcgta tcgtttcatt ataccacaaa caaggggtga
    13681 aaatctattg cagactgtaa aaaatcaaag cctgactgct atccaaatag ctatcaaact
    13741 ttgatttttc tgtcttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc
    13801 cgtaggtata ggtaactgac ttcgtcagtc ttatctacaa cctcaaaact gtgtttttag
    13861 cagcctgcgg ctagcttcct agtttgcact ttgattttca ttgagtatta tcttatctca
    13921 agcccatttg agcgagcttg gtttgatatt tgttttgatc aaccagcaag cccaagcctc
    13981 cataaacatc ataggcatct acccagtcac ccagttctgg aatcgtcaat ttttcaatac
    14041 cattttttgc tccatccaaa acagataaac cgtttgttag gaggaaagta tagggtacgt
    14101 tggttgaggt catagcaaaa acctttccaa gagcttcaga accagtgaaa agtttagtgg
    14161 gatctttaat ttgctctaaa attgctgtta aaacttgttg ctgtcttttt gtacggccgt
    14221 aatccgcctc atcatcatca cggaaacgag cataattgag cagggtcgag ccattcatct
    14281 gctgttttcc gactttaatg gtttgggttg gagactcagt ctcggtagcg tataaatcat
    14341 ctccgactgt agcttctgtt aggggacgcc cattcaatgt tgaaaattga gcatcaatcg
    14401 tcaccccatc agggaaaagc gtgtcaatcg ctgtggcaaa ggcctggaaa tcaaccaagg
    14461 cgtagtactt aatgtccaag tcaaaattat ctttcaagac ttggcgaacc atttctgccc
    14521 ctttttgccc ctcttgttct cctaactcgt aggctacgtt taacttgtta tctgtctgtt
    14581 ttctaccgtt aatcacttga ctataaccat ctatatagac caaattatca cgcatgaaac
    14641 tgactagctt cattttctta tctgagcccc cgacatttaa taccataata gagtcagttc
    14701 gtgtctcaac actgttctgg ccgattcgac catcagtacc catgattaaa atattaactc
    14761 catctctagt gtcctgacca ttaaagactt ctacttgagc tgcccgggca tcagcagttt
    14821 tctttgcgct agcatcttgg taaccacgca aaaacatgaa taccatggcc aaagccacac
    14881 agaccaaaag tgaaaaaatc accataaaaa ttcgtttaag acggagcttc cgtcttttct
    14941 tttttggagg gaaagagagt gcttgtgatt tggattgtga gcgactccgg ttcgcatagc
    15001 ttggtaagtc aacctgctct tctctttctt gttccaagct agagctacta tttcccctag
    15061 caagagttag cttttcttgc aaataggcaa actcattttt ttctctctca ttgagatagt
    15121 gaatattttt tagcaaataa tcataacgca actgctcatg atgacttaag ggattttctt
    15181 tactcatctt ctctcctttc catggtctga tattggataa ataggatagg cacccagaat
    15241 tttatactgg attccaatcg cttctaattc tttttgggca aagtggacca agtccttatc
    15301 ggtataatcc acatcgataa tgaaaaagta ttcacccagt gctgtcttga gtggacgact
    15361 ttcaattttt gtcaagtcaa ttcctcgcca agcaaaggtc gacagggcct tataaagtgc
    15421 acctggaagg ttgtcaggta atgtcaaggc caaactcatc ttttcagttt gtgcttgcaa
    15481 gggaatacta ggcttttcag ctcctagaac ccagaaacgt gtgaaattgg cttccatttc
    15541 ctgaatatcc tcggcaatca gttccaatcc atattcttca gcagaacttc taggtgcaac
    15601 tgctgcaaag ggctggtctg gatgttcgga aataaaacgg gccgcataag ctgtactagc
    15661 tgttacctcg atttgagcct ctggatattg ttcatcgatg aatttctttc cttgagccaa
    15721 ggcctgtgga tgtgaaaaaa tcttttcaat cttagtatgg cctggaacca ccatcaactg
    15781 ctgatgaata ggctgaacga tttctgctac tgcttggatg tgagcctgat gaaaaagata
    15841 gtccaaggtt tcatgaacac taccctcaat agaattttca actggcacca cagaatagtc
    15901 cactaatcct tgctcataag ccttgatgac atctgtaatg ttagcaaaag cctgcaattc
    15961 ctcatgagga aaagctatct gcacaacgtg gtgtgaaaat gatcccttgg gacctagata
    16021 agcaattttc atcttagttc ctctataatt tcctctgggc ttagcttggt cacatccaaa
    16081 acccgactag ccacttcctc ataccaagcc tgtctttctt gaaaaatagc tactagttct
    16141 tccttgctat tatttagaaa aagcggtcgc tgattgtcct tatcagctgc gatacgttgg
    16201 tagagggttt caaaatctgc tttcaggtag atgttatctg tattagtctt gagtaagtca
    16261 cgatttctct gagaaataac cactcctcct ccagttgaca cgacttggtc tgtttgtagt
    16321 aaatcagcta ggacttctga ttctacctga cgaaaggctg cttctccctt ttcagcgaaa
    16381 aaattcgcaa tggacatacc taggcgcttc tcaatcagag catccatatc aaggtaatta
    16441 gggtccaagc ctcttgcaat agtcgatttt ccagccccca taaaccctaa taacacctta
    16501 gccatgaatc aagctctcca aatcatcaaa gaaactagga tagctggtat tgatggcttc
    16561 tgcacggtca agctccacct ctccatctgc aaccaagagg gctgcgatag ctgtcatcat
    16621 gccgatacgg tggtcaccaa acgtattgac tctagcaccg tgaagagctg atttcccttt
    16681 gataatcatc ccatctgccg taggagtaat atctgctccc atactattta aggcgtctgc
    16741 cacaacctga atacggtctg tttccttgac cttgagctcc tcagcatctt taataactgt
    16801 tacaccttgg gcttgggtcg caagtagggc aataataggc aattcatcaa tcaaacgtgg
    16861 aatcaaagcg ccacaaatct ctgttccttt caagtcagaa gactcaacaa tcaaggttgc
    16921 agatttagcg actggatcga tttcagttat ttccaatttt ccacccatgg cacgaatgac
    16981 atcaataata ccggtgcgag tttcgttgat ccccacattc tgcagcacta gacgagaatt
    17041 tggagcaatc aaacctgcga ctaaccaaaa ggctgcactg gaaatatctc ctggtacgac
    17101 caccttctgt cctgtcaatt tttgtggccc ttggactgtg attttcttac catccacact
    17161 taaatgacca ccaaattgtt gcaacatatc ttcagtatga ttacgggtgt attctttttc
    17221 gataataact gactccccct tagcttgtaa ggctgcaaac atcaaggctg acttgacttg
    17281 ggcagaggca attggcaact cataatgaat aggtcttagg tttttcgtcc cttttaagcg
    17341 aaggggaggc aagtctcgtt cagtttgccc tgaaatgctg acgcccattt ttttcagtgg
    17401 aagggtcaca cggtccatag gacgtttgga aagactatca tctccaaaca tctctacttc
    17461 gaaatctgca ccagcaagga cacctgaaat caggcgaatc gaggtgccag aatttcccat
    17521 attaagggca ttttgcggcg cttttaagcc agccatgcct acaccttgaa tggtaataac
    17581 cccatcttta tcctcaattt caacaccaag gtcacgaaaa acctgcatgg tcgaaagaac
    17641 gtcttcacct cgcagaatat cataaacctt ggtctcaccc tcagccaaac ttccaaagat
    17701 aatggaacgg tggctgatag acttgtcacc tgggacgcgg atactaccat gtaaatggcg
    17761 aatgtttgtt tttagtttca tactggacct catacttgca atacttttac ctattttatc
    17821 ataaaaagcc agaaattcct taaaaattcc tgactttagg atagttcttt tcttatttca
    17881 gcaattctga aactggttcg aaaacaattt tttcaatgtc agaaaggtaa atggccaatt
    17941 gttgttgctt ggtaaagaat tctgacaaga ggctatttcc ttgaatctgt ttaccaaagc
    18001 cttccatctt agcttggaag gacgcatctg gcatttgacc tgtctgtgct agtttttgaa
    18061 tttcctcttg aaaggcaaga taatctgtaa agattttgct tgcctcagca tctgctgcaa
    18121 tcgcatcttt agctgcttta acagccttgt attctggtaa tccgcgtaga ccgcgactga
    18181 gttcgtttgc actatcgtaa atatttgaca tgttcttctc cttatttgat gacgactgta
    18241 tagtcggtat tttctgttat gagatactca gctctttcca agtcttgagc atttttaaat
    18301 gaaatttgta ggattccgtg aatatcctca cgattttcct cgttgatgtg gatattaacc
    18361 aaggaagttc cacgtagcag ttccaaaatc cgcaggatga catcttcttc atcaggaacg
    18421 tcaacataga ggtcgtaaga gctatccaca ccaccacgct tatggatttc catggtctgg
    18481 cgttgttcac gcgcttggtt aaaaaagttc caaatttgct cttcatctcc cttactaatg
    18541 gcctgaccaa tcgcttccaa acgttccttg aaatcctcaa ttctatccag aatgatctcg
    18601 ctattggaca agagaatgga ggtccacatt cctggctcgc tttccgcaat tcgggtcata
    18661 tctcgaaaac cacctgccgc aaagcgcctt gccatctcat gctcttgagc atagaccgca
    18721 gtctgctcca tgagactaga agccaaaata tgaggaaaat ggctaatctg agaagtgaca
    18781 cgatcatgct ccttggcatc aatctcgata aaacgagcat gaagacctga aagcagatcc
    18841 ttcatttcct taagcgtgtc ctgacttgtc aggcttgaag gtgtaaagat ataataggca
    18901 ttttcaaaaa gattgacatc tgccgaagca gcccctgtct tgtgactacc agccatggga
    18961 tgggccccga caaagcgaac agacttgcca gccaaatact gctccgccgc atccacaatg
    19021 gttgacttgg tcgaaccagc atctgaaata ataacgcctt ctcgcaaatc caaattggcc
    19081 aactccttaa tgaaagcaat agtttgtttg attggcaagc tgaggataat gacatctgcc
    19141 aaaggagcaa aactagcaaa atcatccgtt gcacggtcaa tcatgccttc tttcaaggcg
    19201 atatctctcg aagcttgact acgattataa cctaaaattt cataatctgg atgatcgcgt
    19261 ttgataccaa gtgccataga ggctccaatc aacccaagac ctgcgatata gattgttttt
    19321 gccataggaa ctccttaata gttctttgta tagtctcggt gtttggctac cgcttctttt
    19381 agttcctcaa gattatctga tgagaatttt tcgaggattt cttgcgccag aaccgttgct
    19441 acaactgctt ccatgaccat tcctgcagct ggaagagcag tcggatcact tctctccacg
    19501 gttgccttgt aaggttcgtg ggtttcgata tccacactca taagaggttt ataaagagta
    19561 ggaatgggtt tcatgacccc acgaacaacg atgggttgcc cattagtcat accaccttca
    19621 aaaccaccta gattattggt acggcgagta taaccgtctt ctttagacca gagaatttca
    19681 tccataactt ggctgccttt acgataacca gcctcaaagc caagaccaaa ttccacccct
    19741 ttaaaggcat tgatagagac aacagcttga gccaatcttg catccaattt tctatcccat
    19801 tggacatagg aaccaagacc aactggaacg cctccgacga ctgtctccac aaccccaccg
    19861 atggtatcac catcacgttt gatttggtca atatagtcct tgatttcctg ttctcgttct
    19921 tggttgacaa tagaaacttc agactgggca gctctttgct taatttcagc gactgtcaga
    19981 ttttcaggaa catcgatttc cttgccacca aagaccacga catggttggc aatctccata
    20041 tccagctcag ccaagagacg tttggctact gcaccaactg ccacccgcat ggtggtttca
    20101 cgagctgatg aacgctccaa agaatttcgc aaatcatcaa aacggtactt aatcccccca
    20161 accaaatcgg catgacctgg gcgaggatga gtaattttcc gcttgctttt aaggcggtct
    20221 tcaatgtcct ccgcagacat gatgtccagc catttctggt ggtccttatt gatgacatcc
    20281 atagtaatag gcgcccctgt cgtcttcccg tggcgaacgc ccgaagtaaa gacaacctgg
    20341 tcactctcaa tcttcatacg accaccacga ccgtagccac cctgacggcg tctaagatcc
    20401 tcattgatat cctcagctgt caatggaagt ccagctggaa ttccctcaat aatagctgtt
    20461 agacgggggc cgtgtgattc tcctgcagtt aaatatctca tacactctcc ttattttacc
    20521 aagtagtctt tcatctcttc cagagaaact gggtgaatgg tcgctgaacc aagctctggc
    20581 accaagacca atttcaaggt gttaccacgc gctttcttgt catgagtaag agcctgataa
    20641 agcttgtcaa ctttccaatt ttcatagtca acaggcaagc cgaatttctg acacatctct
    20701 gtgatagatt gggtaatgcc agctggcatg aggccttttt cctcagcaac cttggaaatc
    20761 tgtaccattc ccatggcaac agcctctcca tgcatgacct tgccataacc ggcagtcgct
    20821 tcgatggcat ggccaatagt gtggccaaaa ttgaggtaaa gacgaatacc attgtccaac
    20881 tcatcttcaa ccaccatctt gcgcttcacc tgacaagaat gttcaatcaa ggtctctgca
    20941 tgttccaaaa tactctcaac agaaccattc agtcccgtca agagagccca cagttctgga
    21001 tcctcaatca agccatactt gataacttca cccatccctt caatcaactc tctttttccg
    21061 agggtttcaa gaacaagtgg atcaatcaga accccatctg gttgggcaaa ggtccccacc
    21121 atatttttag caaatggtgt gttaacgcct gtctttccac cgatagaaga atcaacctga
    21181 gctgtcaaac tagtcggaat ctgaacaaag tgaatacccc gcatataggt agaggctaca
    21241 aagccagcca ggtccccaac aacgccacca ccaagagcaa cgattccatc gctacgagtc
    21301 agaccttgct tgactagaaa ttcatagact ttctgaacag tagttaaatt ctttctttct
    21361 tcaccttcta agaaatcaaa aacagctacc tgaaaaccag catcttctag gctgagcttg
    21421 accttctctg catagagaga ggctacatgg ttatctgtca caatgactac cttttgcggt
    21481 tgccagagtt ctcgcaacca ctgaccagcc tgggccatac aacctttttc aatctgaata
    21541 tcataaggat gatgaggaat atcgattctg attttcatag gagagtctcc ctttctttat
    21601 tggtattttt ctgttaaaga ctgccaaatc tcttctgtcg gcatttcctt gcctgtccac
    21661 agttgaaaag cttctgcagc ttgatagagc aacattccca gaccattgac tgctggattg
    21721 ccctgacttc tagcccattt caaaaacggt gtttcaaagg gttggtatat gatatctgca
    21781 actaaaagag tttctggtaa gactatgttt tcaggaacag gagaggattg gccatccatg
    21841 cccacactgg tggcattaac tagcaaatcc gactcggcaa tccttgcttg cagttcagaa
    21901 acatattcta aagcacacaa atccacttta aagcctgtct gctcctgtaa cttgtctagg
    21961 taaggtcttg ttttttccat agaaacggaa cgaacaaaga ccgaaatctg actgacgcca
    22021 tccaaaatag cctgtgccaa gattgattta gccgcaccac ctgcacccag cagggtcatc
    22081 tttttacctg aaattgtaaa agaaggcaag cacttaaaaa atcccttgcc atctgtatta
    22141 tatccaatta aattgccatt ctcattgaca accgtattaa ccgcaccaat caagcgcgct
    22201 tcatcgctca gctcatccaa ataaggaatc acctgctcct tatagggcat ggacagattg
    22261 atgccaaaca tctggtagcg acgaatattg gccactgttt ctaccaagtc actcgcttca
    22321 atctcccaag ccacataagc accgttggta gctgtcgcct caaaggctct attgtggatg
    22381 aagggagaaa tagaatgctt aataggattg gcaacaactg cagctaaacg tgtatagcca
    22441 tcaagcttca tccaaaatct ccctgatttt tttcatgcta gctagagaaa tctgcccagg
    22501 ggcactaacc tcatccagac tggcaaaaga ccaactcgaa ccagtcacat ccgcagtgat
    22561 acgagagacc ttgcccacct tacccataga aatggtcaca tattcctgtt caggattgag
    22621 ggttttaaag cctcgtgtat agttcatcaa gtctaagaca tcctgctccg tgtgagccat
    22681 caccgcaacc ttaacaagtt ttggatttag gatcgtcaac tctgacaaga tttccatcat
    22741 gttctcaggt gtttcttgga aattatggta actcaaaaca agatttggga agtccagcat
    22801 ttcctcaaaa acatccttgt agctatagta ctcaaaatca atatagtctg gttgatagag
    22861 ttgcgcaact tccttgatta gatggatata ctcttctgga gaaaggtcga tttctccacc
    22921 ttcggagcga gttcgtagcg tgaaaaccaa ctcacggcct gcgaattttt caaaaatggc
    22981 tggagctacc tgcaaaatcg cttctttagg cagatagtcg gcacgccatt caatgatgtc
    23041 ggcatccagg tacctcgtgg catccagagc ctgagcctcc tctaaacttc ttggcattac
    23101 tgaaacgatt aatttcattt actaaccttc atactaatca ccttgaggta attactactt
    23161 tcatcttttt tattataggc aaaatctgct ggaagaccat atttgtttaa aatctggtaa
    23221 cttcttcctg caaagccttt atcaatttgt tctgtaaatt tctgacggga aacattggca
    23281 gcattggtac tggcaatgat aatccctccc ggatttaaaa tctcaagact ctgggaaatc
    23341 aacttgtgat aatccttggc cacagagaaa gtttgttttt tattccgagc aaagctaggc
    23401 ggatctagga caatcacatc gtaggtcaag tttttacgtt tggcatattt gaaatactca
    23461 aagacatcca tgactataaa acaatgctcg tctgtgctga gcccatttgc ctgaaaatgc
    23521 gcttgagaca attctcgtga acgtttggct agatcaacag aagttgtctg gctagctcct
    23581 cccatggccg cagctactga aaaagccgct gtgtaggaaa acatattgag caaggattta
    23641 cccatagcca agccgtcaac taaactaccg cgaacctcat gctggtctag gaaaattcct
    23701 gtcatcaagc catcattcat aaagacttga tacaggacac cattttctaa aacagtgaaa
    23761 aagtcaggtg cttcttgacc ataaacatgg gcagattcat agtccaaacc cttaaagcgg
    23821 attttctcat aagcccctaa aacctcaggg aaaacctgtc taaaggcttc tgatatagtc
    23881 tgacgaatct gataaacata agagttatac caagaaaaga cggcgtagtc gccataaagg
    23941 tccactgtca gacccccaaa gccatctccc tcttgattaa agagacgaaa ggcagttgtc
    24001 aaatcatctt gatagtaggc gtttctcttt tctttggctt ttctaaacaa cgtttcaaag
    24061 aaagcttgat tgaaggccac cttgtctttg ctgacaaacc agcccaagcc cttgttttgc
    24121 tgagaaaggt aggcagttcc aagaaagttt ccttcctgac cctgcacctc tacttcctga
    24181 tccttaagat tgacattctc aagatcactg gcttctagta aaactagccc cttagcaagc
    24241 ttcttttcaa cccttttgct gactcttatt ctattcataa ctaccattat atcaaacttt
    24301 tagacaattc tcaaaaaaga aactaccctt gcttttttac tcttctttta aaaaatggta
    24361 tactagactt cctgcaaaac taggaagtaa atgtgtaaga atcacaataa aaaatgctct
    24421 tccgtcttgg aggagcattt ctttttatca acgaaaatca aatagcaaac tatgaaacta
    24481 gcctcaggtt aactgtgaga ttataggtag agaggttgaa tcagcaatat gtgtctgtca
    24541 aatttagtga caaaggtagt agaagaaaga tgaagaaata aatctgcttc aataggtatc
    24601 tggaaaattt gattttatag aaaagccttt tgttacaaac tcaatatact atcaataaat
    24661 aatattatag aagcaacaat aattaaaatt tcacctattt gcatcattct atttcgaact
    24721 ctaaatatat gttctatcaa aaatacttgg atcacacaca ttataggaat taacgttttt
    24781 gaaattgaaa aatatcccaa taaataaact ataaacaaca ataatagaac tatattatat
    24841 ttcttattca aaacattcct ccctatattt ttgattacca atcttaatca tttacaacta
    24901 cattctaaca aactataaaa gcgtttgtcg aattgaattt atcaagcaag caaccaacta
    24961 tctcatcttt tttctatttc tgccaatatg cgtgacaggt aataatgata gccaaaaata
    25021 gcaagagcaa gcaagacgat aagagctcct actcccaagt tgatggcaag gataggggag
    25081 agagactgaa ccaagaatat gctcccaatt acaagggcca tcaggattgc actataaata
    25141 aacaataaaa ctatggcgac tatgccattt gaacgattca ccaggtccgt aatgctactc
    25201 caattggttg acagattttt aacgtcctta aagtaatggt ggcaagaaag gatgacactg
    25261 gcaatgatcc agactacaag aaggtaaatc atcgaaagga tggacaagcc tagatataga
    25321 gaaagaccga gcaaagtcag aactggtaaa aaggactgaa cagcaaagat aatccaaaat
    25381 ttcactttca cataacgagc aaagtcaaag ggtaaactct tcagaaaatc aacattttcc
    25441 ctctccaagg acaaggcaat tgaatgcagg ctggtgatat tgttattgac aactgctata
    25501 aacactccta caaaaaacaa gggtaaccag tatggaggat gaatgtctgg aactatctga
    25561 gaatctcgga ttttggaaat cagactgatc atcatgagat aaggaaggaa agcacttgta
    25621 aaaagcactg taatcacacc agtcccctgt cccaagaggg tgaggtggta gcgtaaaacc
    25681 atacggaaaa agcccttttt agtagttgaa atcctctcct tgctgcgacg ttcttttttg
    25741 accttctcct cactgttaag caggatcacg tcataaaaac gaggaaggac cttctttttg
    25801 gtcagataaa gcaggaagag agttagtcct atccaagcga gcagacccac taaggcttct
    25861 gtcgaaaaag gctccactgc tattttgtaa aagatatgaa gaggataaag gagaaatgga
    25921 atgtctctaa ctttgtcaac aatacttcca aaagtcgact gaagaaagaa gataaatatt
    25981 aaaggtatga gaactcctat cccaatcatc acattcgaaa aaatagactg atactttctg
    26041 aagaccctag tctgagccaa gaaatgtact gccactaccg tcactaaagt aacagagaca
    26101 aataataagg tcaaggacag tagcatcaaa ggcaaaccca gccaaagaga aggagctaga
    26161 ctaatataga gggctagaaa ataagctagg attggtacaa ttccagttag agctggcaag
    26221 aggacagaca gacctttggc cattataatc tctgattctt taaaggcata gggcctatag
    26281 gaggccaggt ccttactctc ataaaagaca ttgtaaaagg cagtgaaaga agttgaaaag
    26341 gccagcacca gtaaaatagc aaccatcgag ctaaaataaa taggcatttc ctcaaaagga
    26401 aaatgaatgg ctatattact aaaacagatg agcatcaaga gactggaaaa aatgtaagaa
    26461 cttaggactc tagcagaaac atttactttt ttcccaggat tcttagcctg cttctttcgt
    26521 agattagcca gattagcttc ttgagatgaa tagaggatat tgatatcaac taatttttta
    26581 atgaccttga gacgcatccg caacctcctc ttttctacca gcaagactaa ggtagatact
    26641 ttccaaaaac tggtctgggt ggtctttcct caagttctct acactaccac aatagatcaa
    26701 atgccccttt ttcaaaatag caatccgatc acagacttgc tcggctacct caaggacatg
    26761 agttgaaaac aagaccgtct tgcctttttg tgcatgttcc ttcatcattt gcttcaaatc
    26821 aaaggcggcc tggggatcca aaccagtcaa gggttcgtcc aaaacccaaa tatcaggagc
    26881 agacaagagt gccccaatga caaagacttt ctgacgcatt ccgtgagaaa gagtttcaat
    26941 aacctgatag cggttttcag caaaatcaaa aacgttcaat agcctagcta gactagtctc
    27001 caagtcagag ctagtcagat cataggatga agcgatcaat tcccaaaatt cattggccgt
    27061 taagcgtaaa aataagtcag gcgagtctgc tacgtagcca atctttcgtt tgatcgccaa
    27121 gcgattttcc gataactcct gaccgtctac caaaatacga ccactgctgg gtgaaatgat
    27181 actgactagg gattttatgg tggtcgattt tccagcccca ttatgaccaa tcaagcccat
    27241 aatctctcca ttttcaatct gcaaattgag attactcaag gcctctttat caccatacaa
    27301 cttactaaca ttttgaaatt caatcatggg acaactccta tctttatctg tattatacat
    27361 cgctatacta gcactttgat acaaaaaaat caatacttta ttttaagtag ttaaaatagt
    27421 ttccttctat cttacgcaaa cgtttgcgcc gagagatact ttatgataga ataaagaaca
    27481 agattgacaa gtaagaggaa acatcatgca aaatcaaaca ctcatgcaat actttgaatg
    27541 gtatctgccc cacgacggtc aacactggac gcgtctggct gaaaatgctc cacacctagc
    27601 tcatctgggg atcagtcacg tctggatgcc accagccttc aaggcaacca acgaaaaaga
    27661 tgtcggctat ggggtctatg acttatttga cttaggagag ttcaaccaaa aagggactgt
    27721 ccgcaccaag tatggtttca aagaagacta tcttcaagcc attcaagccc ttaaagaaca
    27781 gggaattcaa cctatggccg atgtagttct caaccacaag gctgctgccg ataacaggga
    27841 agcctttcag gttatcgaag ttgatcctgt agaccgtaca gttgaacttg gagaaccctt
    27901 caccatcaat ggctggacta gttttacctt cgatggtcgc caagatacct ataatggctt
    27961 ccactggcat tggtaccact tcaccggtac agactacgat gccaaacgca gtaaatctgg
    28021 gatttatctg atccaagggg acaacaaggg ctgggctaac gaggaattgg tcgataacga
    28081 aaacggaaac tacgactacc tcatgtatgc cgacctagac tttaaacatc ctgaagtcat
    28141 ccaaaacatc tatgactggg ctgattggtt catggaaacg actggtgtag ctggtttccg
    28201 tttggatgcc gttaagcata ttgactcttt ctttatgcgc aacttcatcc gcgatatgaa
    28261 ggaaaaatac ggtgacgatt tctatgtttt tggtgaattt tggaacccag acaaggaagc
    28321 caatctggac tatctcgaaa aaacggaaga acactttgac cttgtcgatg ttcgtctcca
    28381 ccagaatctc tttgaagcca gtcaagctgg cgcaaactat gaccttcgtg gcattttcac
    28441 agatagcctg gttgaactca agcctgacaa ggctgtgact tttgtcgaca accacgatac
    28501 ccaacgagga caagcccttg agtctaccgt tgaagaatgg ttcaagccag cagcctatgc
    28561 cctcattttg ttacgccaag acggccttcc atgtgtcttt tacggagact actatgggat
    28621 ttcaggccag tatgctcaag aagatttcaa agaaatcctt gaccgcctcc tagccatccg
    28681 aaaagacttg gcctatggag aacaaaatga ctactttgac catgctaact gtatcggttg
    28741 ggtacgttca ggtgctgaaa atcaatcccc aatcgcagtc cttatctcaa atgaccaaga
    28801 aaacagcaag tcaatgtttg tcggtcaaga atggactaat caaacctttg tagatttact
    28861 tggtaaccac caaggtcaag ttacaattga tgaggaaggt tatggacaat tccctgtctc
    28921 agctagatcc gtaagtgtct gggcagtcaa taccatctaa tagctcataa taaccaagct
    28981 aggtccaagc ggatttggct tttttgtatt cacaaaaaga cctacccaaa tggatagatc
    29041 tttacttgat tacaatttac ctgctactgc atccaacaat tcttggatct tagcttggtt
    29101 gcttcctcct gccatggcca tgtctggttt accaccacca cgtccatcga tgattggtgc
    29161 taattctttg acaaggtttc ctgcatgaag gtcttttgtc ttgcttgcta caaggacatt
    29221 gactttgtca ccgatagcgg caactaggac aagaagatca gagtagtctt tttgtttcca
    29281 gttatctgca aaagtacgaa gggcaccggc atcggataca gacacttgac tagcaatgta
    29341 acgatgaccg ttgacttcct tagcatcttt gaagatatcg cctgcggctg cagctgcggc
    29401 tttttctttc aactcagcat tttctttttg aagttgacga agttgttctt gaagtccttc
    29461 taccttgtga ggtacttcct tgacttgagg tgctttcaag attgctgcga cagctttaag
    29521 agcatcctct tgttcacgat aggcttcaaa ggcttcctta ccagtcactg ccaagatacg
    29581 gcgagttcct gaaccgattc cttcttcttt gacaattttg aagagaccaa tctcagaagt
    29641 gttgccaaca tgagtaccac cacaaagttc aatagagtag tcaccgatag tcacgacacg
    29701 aacttccttg ccgtatttct caccaaagag ggccatagct cccatttctt tagcagtgtc
    29761 aatatccgtt tcaactgtct taacttcaag agcttcccag attttttcgt tgacttgctg
    29821 ttcaatcgca cgcaattctt cagcagttac agcttggaag tgggtaaagt caaagcgaag
    29881 gaattcaact tcgttaagag atcctgcctg tgttgcgtgg tttccaagga tattgtgaag
    29941 ggcagcgtga agcaaatgag tcgcagtgtg gtttttcatg acacggtgac ggcgattgct
    30001 atcaattgcc aaggtatatt cttggttcaa ggcaagcggt gcaaggactt caactgtatg
    30061 aagggcttga ccatttgggg ctttctgaac attggtcaca gtagccacaa ccttacctga
    30121 ctcatccaag atttgtccgt agtcagctac ctgtccaccc atttcagcat aaaatgacgt
    30181 ttccgcaaag ataagagagg cagttccttc tgaaacagct tctacttctg cattgtccgc
    30241 cacgatagct accaatttag aagacaattg gctagcattg tagttgaaga cactttctac
    30301 agtgatgttt tgaagagttt cattttgcat acccattgag ccacccttga cagctgaggc
    30361 acgcgcgcgt tcttgctgtt ctttcatggc tgcttcaaaa ccttcacggt ctacagtcat
    30421 accagcttct tcagcgattt cttcagtcaa ttcaactggg aacccataag tatcatagag
    30481 tttgaagaca tctgaaccag cgataacaga ttgacctttt tctttcaagt ctgctacaat
    30541 gccttgggca aagtgttgac ctgagtgaag ggtacgggca aatgattctt cttcgctctt
    30601 aacgattttc tcaataaagt cacgtttctc aagcacttct gggtagtagc tttccatgat
    30661 ttttccaaca gttggaacca atttgtaaag gaaaggttcg ttgataccca atttttgacc
    30721 atgcatagaa gcacgacgga gaagacgacg aagaacataa ccacgacctt catttcctgg
    30781 aagggcacca tcaccgatag caaatgaaag agaacgaatg tggtctgcga taaccttgaa
    30841 gctcatgttg tcgccatctt ggtcataaac cttaccagac aatttctcga cttcacggat
    30901 aatcggcatg aagaggtccg tttcaaagtt ggtcttagcc ccttggataa cagccaccaa
    30961 acgctccaaa ccagcgcccg tatcaatgtt cttatgtggc aattccttgt attcgctacg
    31021 aggaacagca gggtctgcgt taaattgtga caaaacgatg ttccagattt caatataacg
    31081 gtcgttttca atatcttctg caagcaggcg aagaccgata ttttctgggt caaaggcttc
    31141 cccacggtca aagaagattt ctgtatctgg tccagaaggt cccgcaccga tttcccagaa
    31201 gttgtcctca attggaatca agtgacttgg atccactccc acttcaatcc agcggttgta
    31261 agaatcttta tcgtctggat agtaggtcat gtaaagtttt tcagcaggga aatcaaacca
    31321 ttcagggctt gtcaaaagct cataagccca agtgatagct tcgtcacgga agtaatcccc
    31381 gatagagaag ttccccagca tttcaaacat ggtatggtga cgcgcagtct tccctacgtt
    31441 ttcgatgtcg ttggtacgga tagccttttg ggcattggta atacgtggat tttcagggat
    31501 aatggtcccg tcaaagtatt tcttaagggt tgctacccca gagttgatcc acaaaagagt
    31561 tgggtcattt acaggaacca aacttactga tggttctact gagtgagctt tggtcgccca
    31621 gaaatcaagc cacatttggc gtacttgtgc actagatagt tgtttcatat tgtctcctta
    31681 tttacttgtt taatgtgatt ggctttccag catttccaca tagtcaatcg cgacacagag
    31741 ggaaatgact aggtctgcat aagcgtcctc aagaaccgtt acggtatagg tagaggtcag
    31801 atggaagagt tccttcttaa tttccgcaat cagctgatcg cgatcatcca gcaatttgaa
    31861 attcaaatcc cagatattgc cctcgatacg aagacctaga ttatcaaact catacttatc
    31921 tcgccagaag gtcaacttct tacgaatgac aaaactcgag ccatcccgaa gctgaatctc
    31981 aaaacgagga agcaaggtca agatttcttt actaatctca ctgacttgtt caccagccgc
    32041 atcatagatg gtaaaggttt taggaatctt aaaaaatgat ccctccacct gataggcaat
    32101 ttctcccctg tcattcttga tagcgaagcg ttcgcctcca agacgaaact tttgtttgac
    32161 aagaaatgtt ttcatcaaca cctccaaaaa tcaaaagaca agctcatatc acgaagggcg
    32221 aaaaaccgcg gtaccacctt cattcaatga acttgtcatt ctcttgttct tatgcaattg
    32281 tatgattgag tagcatgact tcctagctta gatggctcgc agcaccgcca tttctctgga
    32341 ctaagacaag tgaaaatcaa ttctcaactt tcttattata acgttttttt aagcttgcgt
    32401 caactggaaa tgatctccgt tgaattagac caattcccta catctctgat tactttttca
    32461 ggatatattt tttcttactg ccgtttttct ttttatccca aattttcata ttactaaaca
    32521 cagctactag aatatttcca aatataaagg tgcctatcac ccaatatatg gactcagttg
    32581 ttaggtattg tcgatccaag ccatccttta aatggaatag tataacagtt tggttaacaa
    32641 tcataaaggt tggccagaaa ctttttttga aaaaagtaga cattttcatt atttgttgcc
    32701 gctttctgta aggttaatac tcaataaaaa tcaaaaagca aactaggaag ctagcctcaa
    32761 gctgtacttg agtacggcaa ggcaacgctg acgtggtttg aagagtatag gcttagtata
    32821 ctactaggca agcaaataag caaataaaca aataaacaac tagaatagaa aaagataggg
    32881 ctctaaaaac tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac
    32941 gtttatctcc tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt
    33001 ccatttatgg tcaaatttct cataaacttc taggtgtttc atggtttcaa catcgggata
    33061 gaaggcctta tcttcctttg tttcctctgg gagcaattcc ttcgctggta ggtttggtgt
    33121 tgaatagccg acatactccg cattttggag agcattttca ggtttcaaca taaagttgat
    33181 aaaggcatag gctgagtttt ggtttttaac tgttttggga atgaccatat tgtcaaacca
    33241 aagattgctg gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg
    33301 gctggcttca ccagagaagg tcacgccgat tgcaacatta ttctgaatca tatagccctt
    33361 catctcgtcc gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt
    33421 ctcttccaac tgctgcagat ccttggagtt gaggctgtag ccgagggaat tgagtcctag
    33481 tcccagcacc tcacgcgccc catcaaagag catgatagaa ttcttatact ccggcttcca
    33541 aaggtcatcc caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa
    33601 ggttccccag aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa
    33661 ctctggtccg atattttcga ttcctttaat ttttgaataa tcaagcggaa ccaagaggtc
    33721 ttcgtccttc atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc
    33781 accctgcttt atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg
    33841 aattcctgtt tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt
    33901 atagataacc aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat
    33961 tccccacaag acaaggataa tcgctgcaat ttctgctaaa aatgaataga tttttttcat
    34021 gcttgctcct ccttctcacg agagataaag taataaccta caactaggat aatactaaag
    34081 agaaagacta gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag
    34141 taaatctcga ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag
    34201 tcatctaacg aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa
    34261 ggaagcatga tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga
    34321 atcatgtcgc cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg
    34381 gagaaggcca cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta
    34441 aagagaatca agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg
    34501 agtgatagaa aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa
    34561 gtcccgataa tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa
    34621 atcagcatga gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta
    34681 aagctattca tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg
    34741 tagaggacca gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc
    34801 tttccttagt cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatagttg
    34861 aacccatacc atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga
    34921 taacgcggtt cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga
    34981 ccgactgaac cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg
    35041 tctcccactt agttgcacca aggtcgtaac tagcattgat gagattatta tccatatcgt
    35101 ctaagacatt gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga
    35161 taaatgagaa atcagtaaat agcaactgct gtgaaccaat tccgataaat tccaagaatt
    35221 ggttaataga gccattctga ccaaaaatcc cgataaaggc ataagcctta agaagaaggt
    35281 tgatccaagt tggcagaata atcagcataa tccagagttg acggtgtttg agacgggtca
    35341 aaaagagggc cgtcggataa ctgataagca gtgtcacaaa ggtcacaatg cctgcataaa
    35401 gcactgagtt gaaactcatt ttaagatagg tcaagttttg tgacgcaaag taagatttgt
    35461 aattttctaa actgaactgg ccttcgatgt tgaaaaagga ttgaccgaaa atcaagacca
    35521 agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg tactacaaag agtttagagc
    35581 ttgttttctt catctctttc ctcctcgatt gcattgatca aacctgcttc ttgctcttcg
    35641 atttctacgt actcctcaat acgagcatcg aactcttctt cggtttcatt gagacgcatg
    35701 atgtggatgt cttctggttc aaagtccaga ccgatttcct cacccacgat ggccttacgg
    35761 gttgagtgga tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgcacc
    35821 ccacggaaga gctgggtatc gaccttaact tgaagcttgc cttcttcagg aagggtaatg
    35881 cgcaagtcct ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca
    35941 accgcttcaa agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc
    36001 aagatgtttg actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg
    36061 tccacagggg ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc
    36121 atggcaagag cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt
    36181 tgcagttcac gcagttcgta ctgcatgtct gttcttaatt tcaagtccag cgctgacaag
    36241 ggctcatcca acaaaaccac acggggttgg ttgatgatag cacgggcgat agccacacgc
    36301 tgacgttgtc ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc
    36361 atcttgagaa cttccgctac acgttgctcg atttctttct tatcaatgtt acgcaagcga
    36421 agtggaaagg caacattttc aaacacattc atatgtggga acaaggcata ggattggaag
    36481 acagtatgta cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg
    36541 atatctcctg tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc
    36601 gaaccagatg cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct
    36661 ttgagaacct tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt
    36721 gattttttca attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc
    36781 aggtcgccac tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccaatag
    36841 gctttcaccc ccctttccat gacatagcag cagcttttca aatacagctt cctacttgct
    36901 ttcacccaag atccggactt ctctttcaag cgtaatacct gagtgttcct tgactttttc
    36961 gataaccgat tgtatcaagt cctcgtagtc tttggccgtt ccatctgcga cattgatcat
    37021 aaatcctgca tgcttttctg acacttctac gccaccgata cgatagcctt tcaagccagc
    37081 ttctgaaatt aactgacctg caaaatgccc gactggacgc ttaaagaccg agccacaaga
    37141 tgggtattcc aaaggttgct tgagttcacg taggtgcgtc aagcggtcca tttcctgctt
    37201 gataacctga tgggttcctg gggctagggc aaatttaact gacaagacaa ctgcaccaga
    37261 ctcctgaata gctgaatggc ggtaaccaaa agccaagtct ttagcagaca gggtttcgat
    37321 ttctccatcc ttggtcaaga ccttacaaga ctgcaagatg tgagcaatct cgccaccata
    37381 ggcacccgca ttcataaaga cagcaccgcc aacgcttcct ggaataccac aagcaaactc
    37441 aaagccagtc aaactatgac ggagggcaat gcgagttgtt tcaatcaagt tagccccagc
    37501 ttctgcttca atggtatagc catcaacaga aacgttattg agcttgtcac acaagatgac
    37561 aaatccacga atcccaccat cacgaacgat gatattgctt gcattgccaa gaaccatcca
    37621 agggatattt tcttggttgg caaatttcac aacgcgagcc aactcaaaac gatttcgtgg
    37681 aaagaccaaa taatcagcct ctccacctac ttttgtataa ctatagctat gcaagggttc
    37741 cttaaaacgg atatcaattc cttctaagat ttcaagcatt ttttctctta cagacatgtc
    37801 actcttcctt ttacaaaatt cattccatta taccattttt agagacattt gacgaccata
    37861 aaaatacctt gtttggattt tgcataagaa aaagaggttc cccccttttt atgatttttt
    37921 acaaaagatt tccttggttc cataggcaac cagaacgagc tccagtgcta gaatcacttc
    37981 aaccaagact ggatttgtca accagcctac ttggaaaaga gatggtgcca gatcaaagaa
    38041 ggcatgcaag ccataggctg ctaggagata aatccatttc ttctggcgaa cagcttggta
    38101 aacccaaact gtcaaaagta attggaaacc aagcgccaag attcgctcaa aaccaagcaa
    38161 ataaatctgc cagaccgaaa gtgactgaat ggtttttaac atattttcag acagtaattg
    38221 cataacctgt ggattctgag tttgaactgc cgaaagaacg atgtaaagat tgagtaaact
    38281 aataaggcct agaaaaatca actccaagcc accatgccct aggccatagg ccaaggcatc
    38341 tgccttttcc aaacttctct ttttctccaa ccatttgaag aaaacaagac gagccgtttc
    38401 ctcaaaaaat gctgccatgg ctaggccata gataatatag ataagcggat gatcttgcaa
    38461 gagggcaata ctaccgtctt tttgaggatg caaaatcaag atatgcacca gtttttccaa
    38521 aatctgcgaa gagacaaaga aagcgactgc acccaagccc aagacagcta gattaatctg
    38581 gtatttcttt ttggcaaacc aaatgcttcc tatcagaaaa gctagcaaca gcaacatggt
    38641 aataatgata tgaatggtca ttttcttctc ctattctgcc ttttcaatat cttttttcat
    38701 ctcgtcaaca ttgaacttag caaacaagta ttgacggtct tggactggga aacgttggtc
    38761 caactggtca actgctccca cctcgataat gccttccttg atgacaaaat ccatgacatg
    38821 tccaccgaag gtcaaatcat ctgatatgaa gtgcagatgg tagcctgcca cactgacccc
    38881 atggaaaatc tcaggcgtcc agaaaccaac aatagtcccc gcaacattgt cacgactata
    38941 ttccggttga tgggttgcga catcagcaaa cttggtatcg ggtgttgact taggaatcat
    39001 acgcacatgc atatgtgaaa attccccccg aatcttgata gagcggaaaa gattttcccc
    39061 atcataataa gactcaattc gttctttcaa ttccttgtct gtcatctcaa agcgctggcg
    39121 gaaaatgacc tctgcctgat gcggtaccac tgcagcgtaa ggaataaggg catctggtga
    39181 cacttcccca atttctggct ggtctcctga ccctttggcc tgataagcct tgccatccaa
    39241 gacaatcaat tccccatcaa tggaatccaa ggttcccaaa ccaaggtcac catgttctag
    39301 caattctcct actgtcatag taccaccata aaggccagcc atcaaggctc caagggtatt
    39361 gtattgaaat aatttcactg gttcctgcac gttcttatcc attcactttc ttgtctgtta
    39421 ttctataaat cttactccta agtataccac atttgcccct agatgtgaac gagagaaacg
    39481 ctctagacat tgccaagaag gaaaaaaaaa ggtacaatgt aacaaaatca agggaggtct
    39541 ggaatgaaga aacaaagcaa gtacaaagag gtcgtttcct atctgaaaaa tggtatcgag
    39601 tctggacgat ttccgacggg tagtcgcctg ccttctatcc gtcaactgag ccttgacttt
    39661 cactgcagca aggacaccat tcaacgagcc ctgctggaat tacggcacga acaatacctc
    39721 tatgccaagc ctcagagtgg ctactatgta ttagaacaag ggcaacatca agacctagaa
    39781 atcgaggtta ccgacgaaca tgccagtgcc tatgacgatt tccgactctg tgtcaatgaa
    39841 accttgattg gccgagaaaa ctacctcttc aactactatg acaatcaaga aggattagaa
    39901 gacctaagac agtccattca caaactcctc tttgagcaag ctctctactg caaggctaac
    39961 caactagtac tgacttctgg aacccaacaa gccttattta tcctctctca aatatccttt
    40021 cctagacaag ccaaggaaat cttggtggaa cagccaacct accatcggat gaatcgcctc
    40081 ttgattgcac aggggctgga ctatcaaacg attgaacgag gcattgatgg gattgacttg
    40141 gaggagctgg aaggccactt caaaacagga aaaattaaat ttttctacac cattcctaga
    40201 tttcactatc ctctgggaca ttcctattct gagcaagaca aacgatctat tcttaactta
    40261 gctgccaagt atgatgtcta tatcgtagag gacgattatc tgggtgattt ggactccaag
    40321 aagggccaaa ccttccacta tcttgataca gaggagcatg tcatttatat caagtccttc
    40381 tcgaccagcc tttttcctgc ccttcgtatt acagcactca ttcttccaaa tgctatcaaa
    40441 gaagcatttg tggcctacaa aaatatccta gactacgaca gcaacctcat tatgcaaaag
    40501 gccctgtcac tctatattga cagtcaattg tttgaaaaaa atcgtttggc tcgcttgacc
    40561 aatcatgaat cttaccaaaa acaaatcgag gaaaggataa ctaaaacacc ttgtcccctt
    40621 cctcattatc ccctacacga tggtttattg ctagacctga gacagtatcc taaaatcgcc
    40681 agtctcaaac acagtcaacc gggcttggac ttctttgaag aggcctattt aagtacctgt
    40741 ccttatcaat ttgccaaggt gtccctagac aatctggaaa atgttttaaa ctatttaaaa
    40801 gcagaattgg aatgacatcc aactctgctt tttcttattc ttcaacttca gttagacttg
    40861 ctgctttttc aagatagctt tggtaaattc cttcatcctt aagtttttgg atgaccttgt
    40921 ctaccacttc tttcaaatca tcactatttt ttctaagagc aacggcattg gcgtcgccgt
    40981 ccttcatctt caagctgaca gttgcgacag ctaagccagc gtttttagca gcataactaa
    41041 gtgcaacagg ctcatccata tgaacagcat ctacttttcc agcctgcaat tcattgactg
    41101 cttcacccat attagttagg gaagttaatt gagcttttgg caattgttcc ttgaccattg
    41161 attctggaac agtccctttt tgggctgcaa tattagcact ttctaggcta gttaaatcct
    41221 tgtatttttc cacatcagcc ttacgaacca agaaactaat cttgttttca tagtatggga
    41281 ttgaaaaatc aaagacttct tttctctcgt cagtagcact aattcctgca actgctaggt
    41341 cagccttacc agtttgaaga ctggtcaaaa cattgtcaaa actcatgctt gagatttcca
    41401 acttaacccc aagttcatca gcgatagcct gagccatgtc gatgtctgca ccgactacct
    41461 ggttctttcc atcaaccaat gattgaaatt caaagggtgc atagtcagga ctggttgcca
    41521 caactaattt ccccttttgc ttaatggcct caacagctga ctgagaacca ttagaacctg
    41581 actggcaagc tactaagaag aaacttgcaa gaaaattaca taaaacaaat atccattttt
    41641 ttgatttcat aaataaacaa cctctctgtt aattttgtat aattataacg atatccaagt
    41701 tacttgtcaa gtgtttttta aatttttatc tcaaaaatat tttttcgttc aaaaaaagga
    41761 gccatcagtt gatttcaagc tcctttttat acagaattaa actattttat agttcgacaa
    41821 tcttacctgt ttcaaagtag acaacccatt cacagatatt tttagcatag tcaccgatac
    41881 gctccaagta ggaaataact tggaaataat cacgacccgt aacaatggct tctggatttt
    41941 tcttaatctc ttcagtcgca aggtcacgga tagtttcaaa atagtggtta atttgctcat
    42001 ccatggaggc cacccggtat gcgtcgtcaa cagaaccatt aagataaaga tcaagtgctg
    42061 cttccacaac gcttttaact tcacgtccca tttttttaat ttcttcctct acagctggga
    42121 tgcgttcttc ccccttcata cggatggttg cctgggcaat ggctacagcg tgatccccca
    42181 tacgctccac atctgataca gccttaagga cagtcaagac tgtacgcaaa tcttgagaga
    42241 ctggttgttg gagtgcgatc atttcaaatg atttcttttc cagtttcact tcgtattcat
    42301 ttacttctgc atcatcttcg atgacctctt ttgccaggtc acggtcatgc gtgacaaaag
    42361 cacgtaccgt acgattgatt tgtgagagca cttcttgtcc catagcgtag aactggttat
    42421 gtaatttctc taaatcttct tcaaattgag atcgtaacat ctttcatctc cttatccaaa
    42481 ttttcctgta atatagtctt ccgtttcctt gtgttgggga tcaaggaaca tctgcttggt
    42541 atcattaaat tcaatcaaat ctccatctag gaaaaatcct gtcttatcag agatacgtga
    42601 agcttgctgc atggaacggg ttaccagaag catggtgtac ttgtctttta gaccatacaa
    42661 ggtttcctca attttaccag ctgaaatcgg atccaaagcc gaagttggct catccaagag
    42721 gatgatttta ggactagttg ccaagacacg ggccacgcag acacgctgct gttgaccacc
    42781 tgacaatcca atagctgaat catatagacg atccttgacc tcatcccaga tagaggcacc
    42841 ttgcaaggct ttttctacgg cttcatccag aacctgctta tccttaattc cattgatacg
    42901 aagcccgtag acaacattct catagatagt catagggaaa ggattaggtt gttggaaaac
    42961 cattccgatt tccttacgta attcaaccgt atctgtacgc ggactgtaga tgttgtgacc
    43021 attgtacacc acggatccag ttgtggtcac ctctggattg agatctccca tgcggttgag
    43081 agacttgagg agggttgact tccctgatcc agatggacca atcaaggcta taatttcctt
    43141 aggttggaaa gatagggaaa cactattcaa agccttcttt ttattataat aaacggacag
    43201 gtctgatacc tgtaaaatcg catctgtcat acggtttcct ttctaaccaa agtgaccaga
    43261 tacatagtca ttggtggact gtagcttggc attttggaaa atagttgcag tcttgtcata
    43321 ctcaatcaaa tcacccaagt aaaagaagcc tgtatagtca cttgcacgag cagcctgctg
    43381 catattatgc gttacaatga tgatggtaaa gtttttcttg agctcaaaca tggtctcttc
    43441 tagttgcatg gtcgcaatcg gatccaaggc tgaggctggc tcatccatta agaggatatc
    43501 tggcttaaca gagatggcac gagcgataca gagacgttgt tgctgaccac ctgataaggt
    43561 caaggctgac ttgtggagat cgtctttaac ctgatcccag agggcagcct gacgaaggga
    43621 ggtttctacg atttcatcta ggacttgctt atccttaact ccagcacgtt catgcgcaaa
    43681 ggtaatatta cggtaaattg acttagcaaa tggattgggg cgttgaaaaa ccattccaat
    43741 gtgtttacgc atttcataaa cgttgatttc tggacggttg acatcaattc cacgatagag
    43801 aatctgccca gttactttag caatatcaat ggtatcattc atgcgattga gactgcgtaa
    43861 gtaggtagat ttccccgatc ccgacggacc aatcaaagct gtaattttat ttctttcaaa
    43921 ttgcatatca atccccttaa tggattcatt tttaccatag taaacatgga catccttagt
    43981 agaaagggct actttttctt caggaaaggt aaggatatgc ttctcatccc agttatatgt
    44041 tgacatggct tctcctttag gcagcggtta atttcttgtg tagatagctt ccgaacttac
    44101 gagctccaaa gttaaaaatc aggataaaga tcaggagcac agcggcagaa cctgctgata
    44161 caatggttcc atctggaata gtgccttcac tattgacttt ccagatatgg acagccaagg
    44221 tttctgcttg acggaagata gagatggggc tagtcacact gaggatattc cagttagacc
    44281 agtcaagagc tggcgccgat tgccctgctg tatagatcag agctgcagct tcgccaaaga
    44341 tacgaccaga tgccaagacg acacccgtta caatacctgg aagcgcttct ggaataacaa
    44401 catgaaccac tgtctcccag cgagaaatcc caagagccag accagcctca cgttgggtat
    44461 ggtgaacgtg tttcaaacta tcctctacat tacgcgtcat ctgaggcaag ttaaagactg
    44521 tcaaggccaa ggcacctgaa atgattgaaa atccatactc aaactgaact acaaagatca
    44581 agtaaccaaa gagacccacc accactgatg gtaaagagga caagatttca atacaagtcc
    44641 gcacaaagtt ggtaacagga ccttttttag catattcagc caagtaaatc ccagctccca
    44701 tagaaagagg tacagaaata atcaaggtaa tgaccaatag gaaaaaggaa ttgtaaagct
    44761 gaatgccaat cccaccacct gcttgaaaag cagaagacct tccagtcaag aaagaccaag
    44821 agatatgggg caagccccga accaagatat agagaatcaa ggaagccaag attgtcacaa
    44881 tgatgctagc aatcgtatag aggacagctg ttgcaagttt atctaatttc ttagcgcgca
    44941 taatttttct ttcctctttc tttcgtaatc aatttaatca cactgttaaa aactaaactc
    45001 atcaagagca gtaccaaggc cagtgaccag agaacattat tatttacagt tcccatgaca
    45061 gtgttcccaa ttcccatagt taatatagaa gttaaagttg cagctggtgt ggtcaaggaa
    45121 gttgggataa cagctgagtt tccgacaacc atctggatag ctaaagcctc accaaaggca
    45181 cgcgccatcc caaagaccac tgcagtgaaa ataccagaac gggccgcctt caagatcaca
    45241 cgccagatag tctgccagcg agtggctccc atagcgaaac tggcttcacg ataataacga
    45301 ggaaccgcac gcaagctatc cgttgtcata aaggttacgg tcggcaaaat catgacaaag
    45361 aggacggaaa tccctgacaa aatcccaaaa ccagtcccac caaagacact gcgaacaaag
    45421 ggaacgacga cttgcaagcc aataaatccg tacactactg aaggaatccc aaccaggagt
    45481 tcaatagctg gttgcaaaat cttcgcccct tttggtgata cttcggtcat aaaaactgct
    45541 gcaccaatag caaagggggt tgcgataagg gctgagagaa tggtaacgat aaaggaaccc
    45601 aaaatcatag gaagggcacc aaattcttta ctagaaggat tccaaattcc tcccaaaaga
    45661 aagtcaaaga tattcacacc attgacaaag aaggtcgaca agcctttttg cgctacgaaa
    45721 accaaaatca tggccacaag gatgactatc aaagaaagac aggcaaaggt caaacctttt
    45781 cctaatttct ccagacgaga attctttgat ggaagcaaca ttttcttagc taattcttct
    45841 tgattcatta ttgtctccct tccaacactg tcacagttcc ggcagcatct ttttcaacct
    45901 tcatttcctt aatcggaata tacttcaatc ctttgacaat cccttcttgg gtctcatccg
    45961 agagaacaaa attgagaaat tctgcagcca actcattggg ctgccccaat gtatacatat
    46021 gctcataaga ccacaagggc caattattgc tacttatatt ttctggactt aagtcatagc
    46081 cattcaactt catgcttttg accgaatcat ctatataggt aagagataaa taagagatag
    46141 ctcctggact ttttgatacg attgatttta ccgctccatt tgaatcctgc tcctgacttt
    46201 gcatggcaga ctgaccttcc ataatgacag tatcaaaggt agcacgagaa ccagagccgg
    46261 ctgcccgatt gataacagag atgggtaagt ccttaccacc aacctctttc caattggtta
    46321 cctcacctat gaagatttga cgaagttgct ctgtcgttag gttatcaaca tcaacctcct
    46381 tattgacaat cagagccaag ccagctaccg cgaccttgtg gtcaacaaga gcagaagcat
    46441 caattccgtc tttttcctca gcaaatacat ctgagtttcc tatatcaact gccccagact
    46501 gaacctggga caagcctgta ccagaacctc ccccttggac attgaccgtt tttccaacat
    46561 ggatcgtgcc aaattcatct gccgctactt caaccaaggg ttgcaaggca gttgagccaa
    46621 cagccgttat ggattctcca cgatcaatcc agctagcaca gcctactaaa caagccgtca
    46681 gccaaaaagc gataagagac agagcaagct tttttctttt tttcactgtt tttctcctcg
    46741 aaaataatta tgaatactgt gaatttttta agtagttctt tatgagttga cgcatgaatt
    46801 cttaccaaat ttctgcgcaa ttgattattt atataatata ggctatatta ctctttccta
    46861 acctcctttt ttcatatgtg gataaaatct cttgtctatc ccttccccca ttgtcaccca
    46921 ttatagtcat ttcgtgtctc tttttcccct ttttaatgca agggaaatta ctctccttag
    46981 atgataatcc aaaagctaga aaggtatctc aaacctctct actctcccag actagtttac
    47041 aactaaaagg aaaagattct attttatgag aaatctagtt tacaagcggt aagaacgcta
    47101 ataactaaac ttcttgtact ctttgaaaat ctcttcaaac cagtgttttg agctatctat
    47161 ggctagcttc ctagtttgct ctttgatttt cattgagtag taaaactaca tgtaatggca
    47221 atcaagatat caagaatcat cctactaaaa aaatccatac tttcactata acatagaata
    47281 agatatttga ctagcatttt catttgaatc tgaggccttt tggaaaataa tttttcaaaa
    47341 catttccagt aacctttgca aagcccaagc cattgccttt aaccaaaact tggtaccaac
    47401 catttggcag actttctgcc agctgaacga tttctccagc cgcatacttg acaaacgctt
    47461 cttggccaat ttcaaccgac tgttcgacct gactcgattt caaggctaaa ccaagagcga
    47521 aactgggctc aaagcgtttc ttcttaaaag tacccagatg cagtccattg cgagcaatct
    47581 tgagcttccc taaatctggc aaaagttctg gcaagagata aagctggtct ccaaaagtct
    47641 gcaagatacc cggtagattg accttcaaat ggttttgggc aaattcctgc cacaaggcaa
    47701 cttgttcacg gctgaggtta ctcttacttg ccttaaattt aggagctgga ttgttaccct
    47761 taaactgtag atgggcaaca aactgaccct ctcccttaaa ctgatgaggg tacatccgag
    47821 ccgtttctgg caggtcaata ccagctacca ttccattgat atgctctact ggcaacaagt
    47881 caaaatcata ctcttccagc aaccaattga caatctcttc gttttcctcg ggtgcccagg
    47941 tacaggtcga ataaaccaga cgaccacctt cagctaacat ggtcactgca tcctccagaa
    48001 tttctctttg caagctagca cattgactcg gataatctaa gctccaatag tccatagcat
    48061 caggttgctt acgaaacatt ccttcaccag agcaaggggc atcaagaacg attaagtcaa
    48121 aatagccttt aaagaccttg accaagcggt cggcagattc attggtcacc acgacatttg
    48181 tcgctccaaa acgctccatg ttttcaacca aaatcttagc ccgtttgctt gaaatttcat
    48241 tggaaacaag tagcccctcc cctgctagat aggctgccag ttgagttgat ttgccccccg
    48301 gtgcagcagc caagtccaag accttcatac caggactggg ttgggctact tgagccacca
    48361 tttgagcagc aggttcttgc gaataaacta aacctgtagc atgctcaggc gatttccctg
    48421 aaaccttccc atagtggccc caaggggttt gagtaatggc atcagaaaag gaaagttgct
    48481 cttcttttaa gggattgacc cgaaaggccg aaaccgcttc ctcctcaaaa gaggcaagaa
    48541 aatttcttgc ctcatctcct agtatttctt tatatttttc aacaaatcct tctggaaatt
    48601 gcatttaagt tcttttcctt tcgtaaatat aggactgaat ttcctcctgc atctcaagag
    48661 gcaccatcat gaccggctgt ctggtttgaa aatcaggagc ttcaccaaaa agggtcacaa
    48721 cccgatagcc cagactttcc cctaaaatac tagctgcggc ataatcccat ggttgcagat
    48781 aagtgagata ggtcaacaaa cgccctgaca aaatcttggc aaaactaatg gccgcacttc
    48841 catagacacg aacaccaaga accgctcggc tcaaatcagc cagcccccat tcattggttt
    48901 ccagcatacc actattccct gcaatgagaa aatctccaag tggtttagtt ttaaaaggag
    48961 ctaggggcct atcatttaga caaactggaa attccccacc accgtggtaa caatcccctt
    49021 tgaccacatc ataaatcaga ccaaactgtc cctgaccatt ttcaaaataa gccatcataa
    49081 cagcaaaatc ttcctgctgg gctacaaaat tattggtacc atcaatggga tcaatgaccc
    49141 aaaccttgcc ctcttgaacc gaggctcgca gacaaccttc ttcagcacaa atcttatcct
    49201 caagataacg ggacaaaatc tcaccaacca agagttcctg aacttctttg tccagtctag
    49261 tcaccaaatc tgttggagag gacttggttt caacacgcaa gtcttcctgc atatggtcaa
    49321 gaatgtactg acctgctttc ttaacaagct ctttagcaaa ttcaaattta ctttccaaga
    49381 gaaatctttc cttccccttt ttctttggca gcctgaactg ctcggtaaag tgaatagcca
    49441 ctaaccgttt caaattctcg tcccaaacgt ttctcttcgc tcttgcttgg cacgaccgct
    49501 ttgaatccct tataggagtc cagtaacttt ttagcctcta ctttgccttc ataggcagct
    49561 tcaacatcat taaaaaaaga aagcactgaa gcaagttctt cagtgctcca cgacaaatct
    49621 agtgggtaac tatactgttt gttcattaac taataccagc tctcattctt gcttctttta
    49681 gttcttgctt acgataacta cgagggagaa aagcacgaat ctcatcttca ttaaaaccga
    49741 tttgcatacg cttggcatca ataataattg gacgacgcaa aagactagga tactgctcaa
    49801 tcaaatgaag caattccgat accgaaatac tctctacatc aatattcaat ttttgaaaaa
    49861 tttttgaacg agttgaaatg atgtcatcag taccattttc ggtcaaggaa aggatgtgtt
    49921 gcaattcttt tcttgttaaa ggactggtca taatattgtg ttccacaaag ggaaccttat
    49981 gtttttctaa ccaggcctta gccttacgac atgatgtaca gctcggtgat agaaatagtg
    50041 taatcatgct tttctcttct tatctatact ttgctacttc tattatacaa aaaaataaag
    50101 cgcttgacta gggattttta gaaaaaaagc ctattttttc aagaaaaata ggctttttgc
    50161 gaacgattga cacaattgga tttggttaat tcactcttaa cgatggtttt aaatgatata
    50221 tatttttata tatgtaaatt aaaaacatct ttcctttcac ttcctacgac ttttcagata
    50281 cagatagcca aagaagtttt catagagggc aaaaaagagg aggaaggcat gaagaaagaa
    50341 ggtctctggc aaaatcataa taacaggatc cttggctgga tcaaaaagcc aggtatcatc
    50401 tcccacaaag agaatttgat ggaaaagagt aaagaattgg tcaaaaccaa tcaaaactcc
    50461 cccaagtcca atcatcacag gtaagactac tagagccagg agactttttc gataaagaga
    50521 caaaaagtcc tttttcacaa tcctattgac aaagacatag aaacttggca gtgtcactag
    50581 agctactagc tgaaccaaat gaaagagatt cttgaccact gcgaaatggt gcagaccagc
    50641 tgctgacgaa cgaaaatcag gcatctgtaa gacctgacta aaaggattgg tcagataatt
    50701 catcaagata tgaaaattgt attgaatggt ttctggtttt agatagactc gattcgttaa
    50761 gtttagccac tgaatctcca taggatagaa aatccaagcc agataaatgg tcagaaggat
    50821 tgagagggag aggagaaaga gcatagagcc ccaaaaggtc aatttagttt tcatcaaaat
    50881 cccactccgc aaggctagaa accacatgtg tcggtgcgat tggcaggcca gctacttctt
    50941 ctgccttagt aaaacctgtc gtcaccaaga gcgttggaat gccattgtca atcccagccc
    51001 ggatatcagt caaataattg tccccaacca tgattaactc ttcacgttcc aaacctaagt
    51061 gctcaaccgc cttgtccata atgatggcat ttggttttcc gatataaacc ggcttcactc
    51121 gtgtcgctac ttcaagcagc gtaatcagtg agccagcacc tggcaaaaga ccgcgttccg
    51181 tcgggatgtt gaggtcagga ttggttccga taaaatgggc acccttttga atagcaagag
    51241 ttgctgtggc aaatttttca tagtcgactt gccaatccag accaactacc acgtaggcag
    51301 ggttttcctt gtcttccaca taaccagccg ccttgatggc ttccttgagt cctgcttctc
    51361 cgacgacata gacggtcttt tcaagcccca aatcattcat atagtcgatg gttgccaaag
    51421 tcgctgtgta gacagtcgat aggggcgtat cgatattaaa attctgagcc aacatctcct
    51481 taacactctc tggagtgcga gttgtattgt tggttacaaa gagataggga atgccccgct
    51541 tttgcaattc atgaacaaaa gtctctccag cagggattcg gtctttcccc ttataaatgg
    51601 ttccgtctaa atcaattaaa tagcctttat atttcatcta tttctcccta agcctttttt
    51661 atttcttgcc aagtaatgat tgcttgggca ttgataaccc catcacttgt aatttcatgc
    51721 ttgctttcca gtccagtccg ttcaacaacc gatgtaatca ctccacctgg tcgaacttcc
    51781 ttgacatact tgaggttgat tttcttggga atatagtggg tcaaaaaatc cgctcccatg
    51841 acctcaaaaa tccagtccaa gtatttactg ttattgacat gaccattcat atccaagtcg
    51901 taaaaacgaa catggtaatc cttgctgatc ggttcttcca aggactcata cttcggtcca
    51961 cggataagtt ttttatcaaa atcagactgg taaggagcca caatctcagg ttcaacagca
    52021 tggacttttc gactgtcgcg gtccatgaga acaaaggtcg ccatcatatg gatgagctcc
    52081 tgccccgctt cattataaat agtaaagcga cggtagcaaa aaagtcgatt gtagctcaag
    52141 gcttccgttt cgatggtaat ttcttccgca aaacgaggca aacgaaccac ctcaatatca
    52201 tattctgcga taatccagac cagattatag tcttccaaaa tggccttatc actaactccc
    52261 agttcaatcg actgcatccc tgaaacttgc agtgacagca aaatcacatc tggaagtttg
    52321 atatgaccgt tcatatcagc catatcaaaa ggaattttca ttttcatttg ataagttaag
    52381 cccatgatcc tactccaaaa taaatcgttc tgctacagta tctcccaaaa agagacctct
    52441 ctttgtcatg cgaacgtggt caccctcaat ctgcatgagg ccttgttgaa ccaaatctct
    52501 gacaatttct ccataaagtc cagcaaaaga ctgtccaaat ttttcctcaa atcgcgccat
    52561 ggaaaccccg gatttcttgc ggagtcccaa gaacatttct tcttccattt gctccttttg
    52621 actcaggtga tcttctgtaa tacaagcatt gccttcctca accgcactga gataatgacg
    52681 aatgggacca tgatttttat aacgtactcc attgacataa ccagatgccc ctgcaccaat
    52741 accatagtat tcagcattgt cccagtacat gagattatga cgactttcaa agccgggttt
    52801 ggagaaatta gaaatctcat aatgctcaaa acccgctcgc tccagctctg caatgatgta
    52861 ctcaaacatc tccgcttcta gttcctcctt aggcagaggc aatttcccac gtcgcatccg
    52921 gttcataaag accgtatggt tttctaaaat caaactatac aaactcatgt ggggaatatc
    52981 cagtccaatg gctttagcca cattttcctt tacttgctcc atggtctgac caggcagagc
    53041 ataaatcaaa tcaatggaga tgttgtcaaa accagccagt ttcagacgat cgatattttc
    53101 ataaatatcc ttctccaaat gactgcgccc aatctttttc aacatcttat catcaaaggt
    53161 ctggacacct agcgaaacac gattgacagc cgaatttttc aaaacagcta tcttatccgc
    53221 atccaaatcg cctggattgg cttcaatggt caactcttcc aagacagaca agtccaagtt
    53281 tttagtcaag ccattcagta acacctccag ttgcggagcc gacagggctg tcggtgttcc
    53341 accaccgata taaagggttg acaacttttc aatatcataa gaacgaaact cttccagcag
    53401 atgctctaaa tagctgtcga ctggctgatt tttgatgaag acctttgaaa aatcacaata
    53461 ataacaaatc tgggtacaaa atgggatgtg cacataggct gacgttggtt ttttctgcat
    53521 agtaattatt ataccacaaa gactagattc cagataaaaa tcaccatccc cagatacata
    53581 gtccgtccgg agatggtgat ggtttattct tctgttatat caatcacaat ctcttctgag
    53641 tcatcaagag cttcggcttt ttcttgccat tgttccttga gattatttaa ttgatttttt
    53701 gatgcttctg tcgcttgaaa agcataggat ttagcttgag caagtatact gtccacagtg
    53761 atttcacctg actcaacctg ttcttttgtt ttcagaacaa aatctgtagc ctgctcctta
    53821 acttctgtca gtttttcaca gacttgctcc ttggcatact ccggatcttc tctcaaatca
    53881 tctagaaaat cttgagcctg actgcaaact tgtttgccct tatcacttgt taaaaacaag
    53941 gcaagagctg cacctgaaac cgttcctaaa aggattgagg ataatttacc cataaggatt
    54001 ctcctttttt attttttgaa aaatttactt gcaagacgaa gagctgacag acttgcacca
    54061 gtcttgagtg tttttgaacc agctgatgaa gctttcttgc tcaagacacg cgcatggtca
    54121 ttgaggtctg aaacagatag agataaatct gcaacagcac tgaagagtgg atcaattgta
    54181 gccaccttga cattgatatc atctgccaag acattgacct tagccaacaa ctcattggtg
    54241 tgatgcaagg tcacatccac atctgaagtc aaggttttaa tcgtcttttc tgtttcatcg
    54301 atgacacgac caagcttttg tacagtaatg atcagataga ccaaaaagac aatcaaagct
    54361 agggcaacaa gaatatatgc aacttctaac atttagtttt cctcctctgt aatatagtaa
    54421 ggggccttct ttcgattttg ataaataacg atcattatac cgagaccgat aaggacaact
    54481 gacagccatt gggacactcg aaggccgaag aacatgagac tatctgttcg cataccttcg
    54541 ataaccatac gaccgaaacc ataccaaatc aagtaaaagg ccgtgatatg acctcgtctg
    54601 agactcttcc atttccgtct aaaaatcaga atcaaggcaa agccaagcag attccataga
    54661 gactcataaa ggaaagtcgg ttgacggtag ctcccctcaa tatacatctg gtcacggata
    54721 aagccaggta gataatccag attatccact gttgcaccat aagcttcttg gttaaagaaa
    54781 ttaccccaac gccccaaact ttgagcaatc ataacgctag gcgccgcaat atctagaaaa
    54841 tcccaagtat tgatgagttt acggtcagca aagatataga gcacaagaac cccagttatc
    54901 aaaccaccgt aaatggccaa accaccattc caaatggcaa aaatctctcc taaattctga
    54961 ctatagtaat caaatcggaa aataacatag tagagacgag ctcctaaaat agccaaggga
    55021 aaggctacta agataaaatc taaaatatcg tctggtatga tcttctttct aggtgcttct
    55081 ttcatagtca aataaaccgc aagaatcaag cctgtcacaa tacataaggc ataccaacga
    55141 atggctaggg gtcctagttg aatagcaatt ggatcaagca ttttgcacct catttcgagc
    55201 gattagactt gtcagtcgtt cgtcgaacaa acgggtcgca tcaaagccca tttccttggc
    55261 acgataattc atggcagctg cctcaatcac aacagagata ttacgacctg ttttaactgg
    55321 aatacgaata cgaggaatgg ctacgccaga aacttcaagt tcctctgcat tgtttccaag
    55381 acgatcaaag gtcttatgcg tatcgtaatt ttccaaatag acagcaagct gaacctgtga
    55441 agaatccttg acagcactcg caccgtagag actcataaca tcgataatac caaccccacg
    55501 aatttcaatc aagtgtttca aaatttcagc tggttcaccc cagagagtaa tctcatcctt
    55561 ggcaaagata tcgacacggt catcggctac caaacggtga ccacgtttga caagctcaag
    55621 acctgtctcg ctcttaccaa ttccactatc tccctgaatc aagacgccca tcccataaat
    55681 atccatcaag acaccgtgca cactggtacg ttctgccaaa cgagaatcca gatagctaga
    55741 taactctcca gataaacgac tggtagctgc acggctggtt aaaatagcaa tcttacattc
    55801 tctagcagcc tttaacatct cctctggaac caccaaacca cgggcaacaa tgactgctgg
    55861 tgtctcaggt agaaacattt ttttcaaaac ttcataacgg ctgttggaag gcatgctgat
    55921 cagataagac cactccttca tccccaaaag ttgaatccgc tctggtgtat agtagtcaaa
    55981 atagcctgtc atttcaagac caggtcgcgt aatatccgct gtattgattt ccttttcaag
    56041 caactctggt tcaccataga caatatctag tctaagcttt tcaatcactt cttttactaa
    56101 aaccgacatc atttcctcct tcaaatgagt tcttctctct attatatcaa attgtaggag
    56161 gaagtttcag atttttgcag gctttggagt atttatttaa aagaaaaagg actagatttc
    56221 tctagccttt cattgcaatt agaatttttt acgtttacga gctacttctg atttacgttt
    56281 acgttttaca gaaggttttt catagaattc acgtttgcgt gtttcttgaa gagtaccagc
    56341 tttagtaacc gcacgtttga aacggcgaag tgcgtcgtca agagattcat tcttacgtac
    56401 tactgtttta gacatttttt tcactccctt caagttcaat atctatttca ttctacacgt
    56461 aaaaggaata attgtcaagc aaaaatgcgg tttaattttg attttttctt ccatttatac
    56521 aagagttgaa agcgttcaat agaacattgc ttttttattt ttcgagtaag ctaagcgctt
    56581 cagcatctgc gatgatggtt acatcagggt gattttggag gctacttgca ggtaggttct
    56641 cagtcactgg gccagatact gttccggcaa tggcttctgc tttcgactca ccgtaagcaa
    56701 aaagaataat agacttggca tccaaaatgt ttttaatccc cattgaaata gcttgggttg
    56761 ggacgtcttc aatcttggca aagaagcgtg cattggcttc aatagtagac tggtcaagtt
    56821 ctactagatg cgtttgactg tcaaatggag taccaggctc attaaagccg atatgcccat
    56881 tgcgaccgat tcccaagatt tggaggtcaa ctggatggtc agccaaaatt tggttgtagc
    56941 gttcaacttc agcttcagca ttgtccttaa caccacgagg caagaaactt tctttaaatg
    57001 gtttttggtt gaacaagttt tcttgcatga agtaacgata agactgtgga ttgtccccat
    57061 caaggcccac atactcatca aggttgacac tggttagatt tgaaaaatca aggttactct
    57121 caacaatttc cttgtaaaat tcaagtgggc tacttcctgt cgcaagtcct agagtttgag
    57181 ctccattagc caatttttcc ttcaaaatct caaaagcaac ttttccacct tgaacttggt
    57241 tttcaacttt aataactttc atcttttcat cctccatttc tatctatatt tattatatgg
    57301 tatagaccaa tttttgtcaa gtgaaaacga tttaatttct aaaaaaagag cgtccaaact
    57361 tgaaacgtgt tataatggat aggattagaa cttagaaaga atgaacagat atatgaatac
    57421 agctgatttt gatttccact tgccagagga attgattgcc caaacgcccc ttgaaaaacg
    57481 tgatgcctcc aaactcctca tcgtcaaccg tgagacagga gaaatgcaag ataaacactt
    57541 ccactctatt attgatatgc tggaacctgg tgatgccctt gtcatgaacg acacccgagt
    57601 tctccctgcc cgcctctatg gtcaaaaagt ggagacagga ggtcatgtgg aacttctcct
    57661 ccttaagaac actagtggag acgagtggga agttctggct aaacctgcca aacgcctcaa
    57721 ggtcggtact cgtatcagct ttggtgatgg ccgcctcagc gctgtcgtta cagaagaatt
    57781 gacccacggg ggacgcattg tccgctttga ataccaagga attttcctag aagtcttgga
    57841 aagtctggga gaaatgcctc tgccacctta tatccacgaa aaattagatg accgtgaacg
    57901 ttatcaaacc gtctacgcca aggaaagcgg ctctgctgca gcaccgactg ctggtcttca
    57961 cttcaccaaa gaactgctgg cagaaatcca agctaagggt gttcatctag tctatctgac
    58021 tctccatgtc ggactcggaa cctttagacc tgtttctgtg gataatctgg acgaacacga
    58081 aatgcattca gagttctatc aactttctga ggaagctgct gccacccttc gctctgtcaa
    58141 agaaaatggt ggtcgcgtca tcgctgtcgg aaccacttct atccgcacct tggaaactat
    58201 tggttccaag tttgatgggc aaatccaagc agattctggt tggaccaata tctttatcaa
    58261 acctgggtat gagtggaagg tcgtggatgc cttctcaacc aacttccatc tgccaaaatc
    58321 aactctggtc atgttggttt ctgcctttgc aggccgtgaa ttagtcttag atgcctacca
    58381 ccatgcgatc caagaacact accgcttctt cagttttggt gactccatgt ttatttattg
    58441 agaaagaatt tctctaaatc ttctaatacc aataaatcgc taagatatta tttcaaagaa
    58501 catctacaat tgaaactcta gctagctgta gaagaggcct agtacattga aattaaaatg
    58561 cttcccccta gcttcgaaaa tattgccata gattgcgttg actctccaaa ttgattcatc
    58621 tatattttat ttcagcttcc tatattttct tcgctgtttg taaatcaaaa tgcaagacac
    58681 atgagtagca ccatatttgt tactcttatc tgtcctctca agagactatt atgagttatt
    58741 tcagaatcat tcactacttt gaccctgact ctccttagtc tcaaaatcaa agacttatac
    58801 tcttcaaaaa tctcttcaaa ccgcgtcaac gtcaccttgg attatatatg tgactgactt
    58861 cgtcagttct atctacaacc tcaaagcagt actttgagca acctgcgact agttttctag
    58921 tttgctcttt gattttcatt gagtattaaa caaaaagtga acaaagctga attctaatgt
    58981 acagaagact aggcttgttc acttttttat agtcgctata agatgacctt atctatagct
    59041 ttttatatat aattatatat tcagacatac tattatcaat tttgtcgcag ggaggaatct
    59101 gttaacgcac ccattcacca ttatcattga ctctatagcc atctatactt gtattgaccg
    59161 ctaactcacc cgatgcattt acataatacc atttaccacc aacttggaac cattgattga
    59221 ctttcataga accattgctg ttgaggtagt accatgaacc attaacttgt acccaacctg
    59281 ttgccatgga gccatcagta ttataaaaat accacatacc attttcttgt ttccagcctg
    59341 ttgttggagc aactgcttta gctggttcta ctgctacatc tgttccttgg ttagatgtaa
    59401 cagatacagg atatgaagga atagatgatt gctcaggaac aacaactttt tcaggttctc
    59461 tcgtccctct ccttatacgt ctttttacca tctctttagt aatttgacga gaagtagttt
    59521 cttcaattgt tccatcacgt tcatctacag catagattgt agtaagagta attttaccaa
    59581 tttctcctac ttcttgacct ttatcaagag ttgggtcatc gagatattct gtttcgattg
    59641 gaatttcttg gacaagaact tggggcttgg ttcctttttt aacaactctt gtttgagagt
    59701 cttctttttg acttaaagta ctctcagtta cttgtccact ctttccatct acatcataag
    59761 ttatcgttgt aactgttttc ccattctttc ctagagtaat ctcttgctcc tgtcctgcag
    59821 aaaggtcatt gtctgcttca tattcagtag taaatggaac aagaacttct tcaaccttgc
    59881 ttttagctgg aactttgata actgtatccg tggcttcttt tctatcaaca gtaacctgtt
    59941 cggtaacata accagtctct ggattaacat cgtaggtcct tgtcgtagtt acatagccat
    60001 cctctccatc aattgtaaca ggattttcac tacggtcttt tgtttcatct ttttcataac
    60061 gaattcgcgt acttgaaatt ttcttggtta ctaccttagg tttagtcgct acttttacaa
    60121 taatatcccc attgtcagcg tcatcatact ctattccctc ttctttatct ctagtatcat
    60181 ctctgacata ttgaatccca tcagcagcat gaacaaaact tgtattcaga ttcctcctaa
    60241 aaataaagtt agcccgatta ccgcagaacc aaaaatcttt ccgagtttac gtattgcata
    60301 gcgcttatta gtattagatt ttgccattac atcctacttc tagtatagca tcttttctat
    60361 caaacgttaa acaatatact ttatatataa aatagactta gaatgatata ttgattactg
    60421 aactaacact ttaactatat cgtaatcaat ctcatatata aaggattgca gacatcttat
    60481 ctaaatacat gctaatatat ttagatacaa acattccaac ttgataattt tcactcatct
    60541 ttcatcattc cttatacaac tatgcagtat aaatagaata gttttctcat cagaatgaga
    60601 ctattttaat attagataat ttgatagaaa aaacatgaat aaaattggtt gaatttaatt
    60661 ccctaactcg atagaggatt ctattttaaa tttaacaaca gctaggatta cactataaaa
    60721 agtacattac cacctgttcg gctggagaat ctagtcgatt agctccctct tagttacaag
    60781 cttaaagcga ttttttaact aacactaaac cagattaaag aaggaactag aacatctgtc
    60841 ttgtactaat caatatgcta ttttaaagtt tcaaataaac ttggaatgct aattattata
    60901 tttacaataa atagttgact tcgatagaaa cagaaaatag aattcaacat tcttccctac
    60961 ttataccata ataaataaga tccgcaagat agccttttct ctctacacca ttaacaatgg
    61021 tttgtagata ggacattcca gccttttcca tgacacgacc tgaagctggg ttgagactgg
    61081 cataacgtgc tctgaccttt tgaaaacctg cttgagtaaa acaaaagtcc aagatagctt
    61141 tcaaagtctc tgtcatcata ccatttcccc agtaagcctt gcctaacaca tagccaattt
    61201 cacagcttaa atcagcctcg tctatcttaa caatgctgat atctcctatc acttgctctg
    61261 ggttttcttt tagacaaatg gcccatttat aatagttgag attagtatag gaagcaaccc
    61321 aattgcaaat cgagtttcga gtgatttcga catcaggatg gggatcccag gtaacatagg
    61381 tcagattctc agcggatgaa gcccaatttt gaaacatggc ttctgcatca ctctccacaa
    61441 atcttcttaa aatcaaacgt tctgtctgta atatttgcgt accgatagat ttcatgatgc
    61501 tacctcactt ccttatttct atactcgtag taaaaaggct caactcagta acagctagaa
    61561 aacgagtttg tcttctaatt tcttgacgca gttgctgcct ggtttgaaat gcgctctagc
    61621 aagctttttc aaacctagtc atcgttgcag gggtaagacg atgaaatcga actcttcgag
    61681 ttactgaatc tgcctcattt tcttatttct aaactcgggg ttcaagatcc cccagacctt
    61741 ctctcacttt cttatttcaa gatgagaggc tgaaaacctc cagtggaggt ttttcttgct
    61801 ttttaatttc agggcaagaa gctaaaaagt cccccggacc ttcttcgctt tctcatttct
    61861 aggctcaggg taaaaacctc caatggaggt ttttactccc aaaagtcatc aaatacagtg
    61921 atgggtaagt ggcgtttgtg ttggcctttg tgccaccagt tttcaatggt cgcttgagct
    61981 tctgggctga ttgttttgcc ttctaggtag tcgtcaatct ctgcgtaggt gactccaagt
    62041 gcgacttcgt cagctaggcc tggtttatct tcttctaggt ctgccgttgg gattttttca
    62101 taaagggctg gctctgcgcc aagtttctgc aagagctgtt ttccttggcg tttattgagg
    62161 cggtaaagag ggagaatatc cgcaccgccg tcaccaaact tggtaaagaa acctgtgata
    62221 ttttccgcgg cgtggtctgt tccaatgacc gctccgctat gggaaccagc aagggcatac
    62281 tgagcaatca tacggcaacg tgccttgata ttccccttgt tgaagtctga aacaggacta
    62341 cctgtcgctt caactgcagc tgtcatggca tcagctgatt ccttgatatt cacaaccaag
    62401 ctgacatctg gctggatgaa ggctagagct ttttgagcat ctgcttcatc agcttgcact
    62461 ccgtatggca ggcggacagc gataaatttg tagctgtcgt ctcccgtttc agatcgcagt
    62521 tcttccatag ctaattgcgc caaacgccct gccaaggttg agtcttgtcc cccagaaatc
    62581 cctagtacaa aggtttttag gaagggatgt tttttcagat atctttttaa gaaatcaata
    62641 gaacgacgga tttcttcctg ggcatcaatc actggtttga cacccagctc ttggataatc
    62701 gtttcttgca aactcattct tcttctcctt caccaagggc ttccttgcgc atcttatcaa
    62761 tcaagtccat cttatcttgc catacatcac gagccaaatc cactggatag tgctgcggat
    62821 tgagcacacg cttatactca tcccacaact tgtcaaattc cttacgggca taatcctgaa
    62881 tgtcagtcaa actaggcaag ttgtaaacta atattccttc tttgaagata tccaccaaga
    62941 gaggaacggc atcaaaatta cgaaccgtct tcttgatgta tgtataggtc ggatggaaca
    63001 tcttgatttc tgtcatgtcg ctaatatcca caccatcata agtgatatag tcgccttctg
    63061 acttgccttt ttcacgactg gtaatgcgcc acacctgctt cttacctggc gtagagactt
    63121 tttccgcatt attagacagc ttaatcgtat tgcgcatctg accagtttca tcttcgattg
    63181 caacaatctt gtaaactgca ccaagagctg gctggtcata ggctgtaatc agcttggtac
    63241 ccacgcccca gacatcaatc ttggcctttt gcatcttgag gttgaggata gtattttcgt
    63301 ccaaatcatt agaagcataa atcttagcct ctgtaaatcc agcctcgtcc agttgttgac
    63361 ggactttctt agaaatgtag gcaatatccc cagagtcaat ccgcacaccc ataaagttaa
    63421 tctgatcacc cagctcacgc gccacctgaa tggcagctgg tacaccgatg cgaagggtgt
    63481 cataggtatc cacaagaaag acacaatttt tgtgggtcgc agcgtaagcc ttgaaagctt
    63541 catagtcatt gccataaacc tgtaccaagg catgggcatg ggttcccaaa acaggaatgt
    63601 caaagagctt acccgcacgc acgttgctgg ttccattggc gccaccaatc accgctgcgc
    63661 gtgttcccca gatggccgca tccatttctt gagcccgacg tgtcccaaac tccatcaagg
    63721 gttcatcttc gataaccgaa cgaatacgag ctgccttcgt cgccaccaag gtctggtagt
    63781 tgacgatgtt caaaagagcc gtttcgacca actgacattg ggctagaggt ccttccacct
    63841 gcacaatcgg ttcattagca aaaaccaaat ccccttcttg ggcagaacga acggtcaact
    63901 ccaacttgaa attgcgaagg taattcaaga acgccccatg ataaccaagc aactccaaat
    63961 aggctatatc actatctgaa aaacgcaagc cttcaagata gttcacaatt ctttccaaac
    64021 ctgcaaaaac cgcatagccg ttcttaaaag gctgttggcg gaaatacacc tcaaagaccg
    64081 ccttcttatt gtgaatccct tggtcaaagt aaacctgcat catgttgatc tggtacaagt
    64141 ccgtgtgcaa tgtcaaacta tcatctggat acatactttt cctacttcct tagctagaaa
    64201 cccatgaaaa ttttcaagaa ctttcatgta ttccaataaa ttagtactat tatatcacat
    64261 tttagctgga ttgagaaaag agtaacaagc tattctccac tctccaattc atccatatct
    64321 tgttcaaatt ttttctgagc ccattcgcca tagctcttaa gaccaagatt gccaataaag
    64381 atccacggaa ggtaaatgat ataagtaatg acccaagcag acaggtattt aaaattcaaa
    64441 ggattgtgct gataaatttc tatgttgaat tgataattct gcaacatcaa aagagccgta
    64501 atagccaagg ttaggaaaaa acaacccaaa atcgtaaaat gaaaacgact atagtaggtc
    64561 actcccagat aacgggcacg attgaaaaag taaaatgtcc ctatgatgat aacgattagc
    64621 agcatattag aattaaaaag gcttggtgct aatactgaaa tgatataaga taggagcgac
    64681 aaagcaatgc agatatagaa actttcagag cccgctttat tgaacagttg ttcttctctt
    64741 tcgtctagta attgataata ataaaatcta tttttcatct tcttcctccc aaaatagttg
    64801 gtctagggtt ttccctaaac atctgcaaat agactggcag agcgagagac tgggattgta
    64861 ttttcccgcc tctattaaac caatagtctg gcgtgtcacc ccgacagcct ctgccagttg
    64921 accttgtgtt aaatcacgct ctacccgagc taattttaat tttaaatttt tagccacctt
    64981 cgtcctcctt atagttttaa tactcatcta ctcttaaaaa atccaaaacc aacacaagct
    65041 atcagctatt tattataacc ccattaattt gcattccagt attatcttca gccgaaaatc
    65101 agtattttag gttgtttgaa ataaacttcc tagtttactc ttttattttt atttagtatt
    65161 agctttagta agatctttta aacgaatttt tattgcttat atttcttgtt tagtttagtt
    65221 ggtttcatat cactattata taatgctttt ggaaatgagc ctagtataag tcaaaaacgt
    65281 gttgaatagt gaaagcagga gcataccaag atgactgatt ttttactgta ttttaggtat
    65341 gcaaaataat actaaatgaa actaaaatga atacttcttg cttttcttga gagtgaaaaa
    65401 gtacaataaa atgattgtag tgattaccac aagatactga ctaatagaca tcgtatttga
    65461 agccacaaat acaggtaaag aataaaaagg aagaagttca attgctttga taaacaaatc
    65521 attactagta ttcatcatca tcgtatttaa tatattaggg ataaagagta gtaaagctac
    65581 taaaatacca aataccaagc cacttttcaa tttgtataaa tagaaaatgt aagataatag
    65641 aaaataaaac aggactaaca aaattgtatt gactacaata gctactataa aatctaatcc
    65701 taaatcacct ggaataccca atttacttac tatgactagt atcacaatgc cattcaaagc
    65761 ataaataatg gaaactgaga tggcatatag aaaattagac aagacgtaaa tcatccgatt
    65821 cttctgttga ttataaaaca aacttaccgt attgtgggaa aaatctctac taataactcg
    65881 attagcatgt ataacagcca ttaacatacc gagcatagca taaaagtttg aaatatgctt
    65941 aataccaagc gatgtctctt gagtctttag aataaagaat gtaagcaata tcggcggtat
    66001 aaacgagata agcaaactga gatatattac gcctgatgaa tataaatttc ttatattttc
    66061 cttaagaaaa ttcaatttat ttaatttcat gattataacc ttcctttatt ttgaacgatt
    66121 taagtaaata tctttaagcg tctctttttt agtttcaaaa tcaactactt taatagagtt
    66181 ttcgttaaaa aatttaaaaa gctcactact ttgaatattc ccagacatag taattctcag
    66241 tccctcttcc tgaacaatat ccccaaattc ttgtttggta atgaaaatgt ctctatctgt
    66301 agctgatgaa aaagctatct caaacaagaa attatgacta tcttttccta ctttttgaaa
    66361 tgtcaaaagc ccgctctcca agaaaagaac cctctcacaa atttcttcaa tgtcttctaa
    66421 tttatgactc gatattaaaa ttcccacgtt ttcatttaaa gctaattttt ttagaaccgc
    66481 taaaactatt tgtgatgatt caatatctaa accattagtc ggttcatcta aaatcaatat
    66541 atcaggtttc gtaacgagag ttagaagcaa agctaatttt tgttttgtac ccaaagaata
    66601 ggtctttact tttttattaa tagactgagt caaatctaac tcttggatca aacttctaaa
    66661 tctttcttga ttgtagtcaa caccatataa atttgacaaa tattttaaat tctctaaacc
    66721 tgttt
//
LOCUS       DAVMJI010000009        58813 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.009, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000009 DAVMJI010000000
VERSION     DAVMJI010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.009"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(157..498)
                     /locus_tag="VYR58_000669"
     CDS             complement(157..498)
                     /locus_tag="VYR58_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV3621871.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            622..1473
                     /gene="rgg"
                     /locus_tag="VYR58_000670"
     CDS             622..1473
                     /gene="rgg"
                     /locus_tag="VYR58_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV3621872.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRKTPDS"
     gene            1664..2911
                     /locus_tag="VYR58_000671"
     CDS             1664..2911
                     /locus_tag="VYR58_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV3621873.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSAFILFLGKSKLSLSISSADGEKLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQVCVLLAIIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            2989..4278
                     /locus_tag="VYR58_000672"
     CDS             2989..4278
                     /locus_tag="VYR58_000672"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV3621874.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            4269..4349
                     /locus_tag="VYR58_000673"
                     /pseudo
     CDS             4269..4349
                     /locus_tag="VYR58_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4421..4768
                     /locus_tag="VYR58_000674"
     CDS             4421..4768
                     /locus_tag="VYR58_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621875.1"
                     /translation="MIDKVVRNLLLTFFLCKMTKIINFLTTILVKKKKMCYNVSKLRE
                     KKKGNAEMSRLLQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQ
                     RIEDIQTVEFDGE"
     gene            4778..4984
                     /locus_tag="VYR58_000675"
     CDS             4778..4984
                     /locus_tag="VYR58_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3621876.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            4984..5181
                     /locus_tag="VYR58_000676"
     CDS             4984..5181
                     /locus_tag="VYR58_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621877.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            5237..5917
                     /locus_tag="VYR58_000677"
     CDS             5237..5917
                     /locus_tag="VYR58_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV3621878.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVAIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            5929..6570
                     /locus_tag="VYR58_000678"
     CDS             5929..6570
                     /locus_tag="VYR58_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3621879.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            6588..6818
                     /locus_tag="VYR58_000679"
     CDS             6588..6818
                     /locus_tag="VYR58_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621880.1"
                     /translation="MKRVILVAVIQAVILFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            6854..6934
                     /locus_tag="VYR58_000680"
                     /pseudo
     CDS             6854..6934
                     /locus_tag="VYR58_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7215..8978
                     /gene="aspS"
                     /locus_tag="VYR58_000681"
     CDS             7215..8978
                     /gene="aspS"
                     /locus_tag="VYR58_000681"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV3621881.1"
                     /translation="MKRSMYAGRVREEHIGQEIALKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            8956..9897
                     /locus_tag="VYR58_000682"
     CDS             8956..9897
                     /locus_tag="VYR58_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV3621882.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(9933..10121)
                     /locus_tag="VYR58_000683"
     CDS             complement(9933..10121)
                     /locus_tag="VYR58_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621883.1"
                     /translation="MRFNVGRFTSFSTEIESFPKIFLYSMKIKVQTRKLAAGCSKHGF
                     EVADRIDEVSNIYTARRR"
     gene            complement(10188..11174)
                     /locus_tag="VYR58_000684"
     CDS             complement(10188..11174)
                     /locus_tag="VYR58_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV3621884.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(11184..11984)
                     /locus_tag="VYR58_000685"
     CDS             complement(11184..11984)
                     /locus_tag="VYR58_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV3621885.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(12237..13079)
                     /locus_tag="VYR58_000686"
     CDS             complement(12237..13079)
                     /locus_tag="VYR58_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV3621886.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(13081..14373)
                     /locus_tag="VYR58_000687"
     CDS             complement(13081..14373)
                     /locus_tag="VYR58_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV3621887.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(14484..15755)
                     /locus_tag="VYR58_000688"
     CDS             complement(14484..15755)
                     /locus_tag="VYR58_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV3621888.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            16305..17822
                     /gene="malQ"
                     /locus_tag="VYR58_000689"
     CDS             16305..17822
                     /gene="malQ"
                     /locus_tag="VYR58_000689"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV3621889.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLGASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            17848..20106
                     /gene="glgP"
                     /locus_tag="VYR58_000690"
     CDS             17848..20106
                     /gene="glgP"
                     /locus_tag="VYR58_000690"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV3621890.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(21151..21723)
                     /locus_tag="VYR58_000691"
     CDS             complement(21151..21723)
                     /locus_tag="VYR58_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621891.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(22522..23370)
                     /locus_tag="VYR58_000692"
     CDS             complement(22522..23370)
                     /locus_tag="VYR58_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV3621892.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            23522..23800
                     /locus_tag="VYR58_000693"
     CDS             23522..23800
                     /locus_tag="VYR58_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621893.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            23802..25865
                     /locus_tag="VYR58_000694"
     CDS             23802..25865
                     /locus_tag="VYR58_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV3621894.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(25943..27199)
                     /locus_tag="VYR58_000695"
     CDS             complement(25943..27199)
                     /locus_tag="VYR58_000695"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV3621895.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            27341..29806
                     /locus_tag="VYR58_000696"
     CDS             27341..29806
                     /locus_tag="VYR58_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV3621896.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            29871..30782
                     /locus_tag="VYR58_000697"
     CDS             29871..30782
                     /locus_tag="VYR58_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV3621897.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            31012..31710
                     /gene="dapD"
                     /locus_tag="VYR58_000698"
     CDS             31012..31710
                     /gene="dapD"
                     /locus_tag="VYR58_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV3621898.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            31778..32908
                     /locus_tag="VYR58_000699"
     CDS             31778..32908
                     /locus_tag="VYR58_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV3621899.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            32920..33459
                     /locus_tag="VYR58_000700"
     CDS             32920..33459
                     /locus_tag="VYR58_000700"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV3621900.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            33443..34120
                     /locus_tag="VYR58_000701"
     CDS             33443..34120
                     /locus_tag="VYR58_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV3621901.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(34187..35086)
                     /gene="galU"
                     /locus_tag="VYR58_000702"
     CDS             complement(34187..35086)
                     /gene="galU"
                     /locus_tag="VYR58_000702"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV3621902.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(35108..36124)
                     /locus_tag="VYR58_000703"
     CDS             complement(35108..36124)
                     /locus_tag="VYR58_000703"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV3621903.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            36336..36717
                     /locus_tag="VYR58_000704"
                     /pseudo
     CDS             36336..36717
                     /locus_tag="VYR58_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(36891..37316)
                     /locus_tag="VYR58_000705"
     CDS             complement(36891..37316)
                     /locus_tag="VYR58_000705"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV3621904.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(37384..38034)
                     /gene="phoU"
                     /locus_tag="VYR58_000706"
     CDS             complement(37384..38034)
                     /gene="phoU"
                     /locus_tag="VYR58_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV3621905.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(38049..38801)
                     /gene="pstB"
                     /locus_tag="VYR58_000707"
     CDS             complement(38049..38801)
                     /gene="pstB"
                     /locus_tag="VYR58_000707"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV3621906.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(38803..39618)
                     /gene="pstA"
                     /locus_tag="VYR58_000708"
     CDS             complement(38803..39618)
                     /gene="pstA"
                     /locus_tag="VYR58_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV3621907.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(39611..40474)
                     /gene="pstC"
                     /locus_tag="VYR58_000709"
     CDS             complement(39611..40474)
                     /gene="pstC"
                     /locus_tag="VYR58_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV3621908.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(40592..41467)
                     /locus_tag="VYR58_000710"
     CDS             complement(40592..41467)
                     /locus_tag="VYR58_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV3621909.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(41634..42965)
                     /locus_tag="VYR58_000711"
     CDS             complement(41634..42965)
                     /locus_tag="VYR58_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV3621910.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(42966..43673)
                     /locus_tag="VYR58_000712"
     CDS             complement(42966..43673)
                     /locus_tag="VYR58_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3621911.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(43757..44059)
                     /locus_tag="VYR58_000713"
     CDS             complement(43757..44059)
                     /locus_tag="VYR58_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV3621912.1"
                     /translation="MTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(44046..44267)
                     /locus_tag="VYR58_000714"
     CDS             complement(44046..44267)
                     /locus_tag="VYR58_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV3621913.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            44229..44788
                     /locus_tag="VYR58_000715"
                     /pseudo
     CDS             44229..44788
                     /locus_tag="VYR58_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(45103..46794)
                     /locus_tag="VYR58_000716"
     CDS             complement(45103..46794)
                     /locus_tag="VYR58_000716"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV3621914.1"
                     /translation="MNTKELIASKLSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTIAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            46930..47376
                     /gene="argR"
                     /locus_tag="VYR58_000717"
     CDS             46930..47376
                     /gene="argR"
                     /locus_tag="VYR58_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV3621915.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            47427..49961
                     /gene="mutS"
                     /locus_tag="VYR58_000718"
     CDS             47427..49961
                     /gene="mutS"
                     /locus_tag="VYR58_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV3621916.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            50108..51802
                     /gene="patA"
                     /locus_tag="VYR58_000719"
     CDS             50108..51802
                     /gene="patA"
                     /locus_tag="VYR58_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV3621917.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLAG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(52132..52395)
                     /locus_tag="VYR58_000720"
                     /pseudo
     CDS             complement(52132..52395)
                     /locus_tag="VYR58_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            52593..54359
                     /gene="patB"
                     /locus_tag="VYR58_000721"
     CDS             52593..54359
                     /gene="patB"
                     /locus_tag="VYR58_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV3621918.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            54498..55187
                     /locus_tag="VYR58_000722"
     CDS             54498..55187
                     /locus_tag="VYR58_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV3621919.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            55191..55370
                     /locus_tag="VYR58_000723"
     CDS             55191..55370
                     /locus_tag="VYR58_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621920.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            55357..56706
                     /locus_tag="VYR58_000724"
     CDS             55357..56706
                     /locus_tag="VYR58_000724"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV3621921.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            56830..58290
                     /locus_tag="VYR58_000725"
     CDS             56830..58290
                     /locus_tag="VYR58_000725"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV3621922.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            58304..58735
                     /locus_tag="VYR58_000726"
     CDS             58304..58735
                     /locus_tag="VYR58_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV3621923.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
BASE COUNT        17192 a        11149 c        12781 g        17691 t
ORIGIN      
        1 ttttgagctg acttcgtcag ttctatccat aacttcaaaa cagtgttttg agcaacctgc
       61 ggctagtttt ctagtttgcc ctttgatttt cattgagtat caaaaagcaa gccatttttg
      121 gcttgctttt ttcatcttta aaaatgattg gcctgcttaa cgaggtggta gtccaagggc
      181 aatacggcca tagcgactga ttcgtgtgat tttccaagca ggcgaccagg taacttcaac
      241 cttgatatct ttgataccct cgatttgttt cagacctgcc acgatttcaa taggcaggct
      301 ttcggcgcaa tcacaggcag tatcggtgaa ggtcatgaca atcttgcaga gccccgtttc
      361 atccagattg atttcataaa tcagacctag attgtaaaca tccaattcca catctgtatc
      421 aaaaactttc tctagttttt cgatgatttg gtcttgcaag gccaaagcac ggtcattgat
      481 tttgatatcg tctctcatag cagtccctcc acgtgataaa tatcctctat tttctcataa
      541 ttctgacaat ttggcaagtt tttgatgaat tttctgaaaa atatgataaa atgaagaaaa
      601 tacggaatca aggggaagtc tatggagcag attggaaaag tctttagaca attacgagag
      661 tcaagaaata tctcactgag acaagcaacc ggaggacaat tttcgccgtc tatgttgtcc
      721 cgttttgaaa caggtcagag tgagctttcg gtggaaaagt ttctatttgc tctggaaaat
      781 atatctgcca gtgtggagga gatcctcttt ctggcgagag gtttccagta tgatacagat
      841 tctgagttga gaaaagaaat tacagatgtc ttggaaccaa agaatatagc acctcttgag
      901 gacttatatc gcagggagta tcaaaagcat gcccattctc acaacaaaca gaaacatatt
      961 ctaaatgcca ttattatcaa gtcttatatg aagagcatag atgaaagggt agacttaaca
     1021 gcagaggaag gaaaagtcct tcatgattat ttgttttcta ccgagatctg gggaatctat
     1081 gaactcaatt tattttcagt cagttctcca tttttatctg tttctctttt tactagatat
     1141 gtacgagaaa tggtacgtaa atctgatttt ctaatggaaa tgtctggcaa tcgaaacctt
     1201 tttcatacta tactattgaa tggcttttta gctagtattg agtgtgaaga atttaccaat
     1261 gcctattatt ttaaacgtgt tatcgaagag catttctaca aggaaaatga gacctatttc
     1321 cgaattgttt atctgtgggc agaaggtctc cttgatagca agcaaggtag agtcaaggaa
     1381 ggccagaaaa agatggagga tgctgtccgt atttttgaga tgcttggctg taataaatct
     1441 gccgaatact atagaaaaac tcccgattct tgaatatctg caaaccaaga aaaaatttga
     1501 agcgatagaa ctgttgccct ctctcaggtc attacaaaag ttctatcgtt tttttgctca
     1561 ttttgtttgt tgcatatatt caaaagaatc gtttcgcaaa ttcataagtg ctatactaaa
     1621 gctattcttg atgtagaact tagaacaagg agggagatta tctatgaaac tattgtttag
     1681 aaatccagct tatagaattt tgactttatc acgcttcttc aatgcttttg gtgcttcgat
     1741 tttcaacctg gtctttatcg tctatgcatc gaccttgtca caagcatctt ttgctgttgc
     1801 tatggcgaat attgtcatga ttcttccgac cctctttaca gtttttgtag ggattcgggc
     1861 agattacacg agggacaagg tcaaatggat ggtctatagc ggtttgtttc aggcggttct
     1921 attttttcta gcagccctag ttgttcagca agctagtctc tttgcctttt ctagcctgtg
     1981 tttgatcaat gtcattagtg atatcatcag tgattttgca ggtggcctgc gtatgcctct
     2041 tattaaggaa aaagtagctg aagatgatct gatggaggct tattcttttt cacagttcat
     2101 cacctatatt tcagctattg gtggtcaagc tttcggagtc tggctcttag ctctatcggt
     2161 caacaatttt tccctcgttg cgggaattaa tgcttgcttt ttcctcgtat cagcctttat
     2221 tcttttttta ggaaaaagca aattgagcct gtcaatttca tctgctgatg gtgaaaaact
     2281 aaaaaatgag aagctttcta tcaaagacca gttcctaaca atttaccgaa atttacgtct
     2341 cgtttttctt aaaagtggac agaaaaactt tggttttatg ctctttgctg tcttgcttat
     2401 taattccttg ggtggcgctt tgggtggaat ttataatatc ttctttttga gccattctct
     2461 cttgaatttt tcttatacag aggcactatt tatcaatcaa gtctgtgttt tgttagcaat
     2521 catcattagt agccttacgg gcaatgatta ttttgggaag cagtccttgc ctagattgat
     2581 gatgtgggag accgtaggac ttagtctagt tggtttggct aatttattca atcaagtcgt
     2641 gcttggtttg ctatttctct tctttactct gtatgtgtct ggtaaagttc aaccaaagat
     2701 tagtgccatg ctcatgaaaa atctagctcc agaggttcta gctcgtacta gtaatttttt
     2761 aggtctattg tttaccttat ccatacctgt gggaacagct tgtttttcac tagtagccgt
     2821 atggaatata cagttgactt ggatgctatt tgttggtttt tccttgctag ctattttttt
     2881 gacaattctt aatctcaaaa atgatatcta aatcctaatt tttttcttac tgttttaatc
     2941 cctttattta tggtaaaata agactattaa gtttaaagag gattccctat gaaattacaa
     3001 aaaccaaaag gaacgcagga tattttacct gctgaatctg ccaagtggca gtacgttgag
     3061 ggctttgccc gtgagatttt caagcgctat aactatgcag aagtgcgcac gcctattttt
     3121 gagcattacg aggttatcag tcgctctgtc ggagatacaa cggatatcgt aaccaaggaa
     3181 atgtacgatt tttatgacaa gggtgaccgc catattaccc tccgtccaga aggaactgcg
     3241 cccgttgtcc gtgcctatgt ggaaaataaa ctcttcgccc cagaagtgca aaagccaagc
     3301 aagttctact atatgggacc tatgttccgt tatgagcgtc cacaggcagg gcgcttgcgc
     3361 caattccacc agattggtgt tgagtgtttt ggctctagca atccagctac cgatgtggaa
     3421 acaatcgtta tggcagccca ttttttgaag gaaatcggta ttcaaggtgt caaattgcac
     3481 ctcaacactc ttggaaatcc tgagagccgt gcagcctacc gccaagcctt gattgactat
     3541 ttgacaccgc tcaaggagac cttgtctaag gatagccaac gtcgcttgga ggaaaatcct
     3601 cttcgtgtct tggactctaa ggaaaaagaa gacaaggtgg cagtagagaa tgcgccgtct
     3661 atcttggact ttcttgatga agaaagccaa gctcattttg atgctgtgcg tcagatgttg
     3721 gaaaatcttg gagtagatta catcatcgat accaatatgg tgcgtggtct ggactactac
     3781 aaccacacca ttttcgagtt tatcacagag attgagggca atgacttgac agtctgtgcg
     3841 ggtggtcgct acgatggttt ggttgcttac tttggaggcc ctgaaactgc tggatttggt
     3901 tttgggcttg gtgtagagcg cctgcttctc atccttgaaa aacaaggcgt ggccctccct
     3961 atcgaaaatg ccctagatgt ctatatcgca gtcttgggtg atggagcaaa tgtcaaagcc
     4021 ctagaactag tccaagctct tcgccaacaa ggtttcaaag cagagcgtga ttacctcaac
     4081 cgtaagctca aagctcagtt caagtcagcc gatgtctttg cggctaagac cctcatcacc
     4141 ctaggagaga gcgaagtcga aagcagacaa gtgacagtca agaacaacca aacccgagaa
     4201 gaagtgcaag tgtcacttga gacaatcagc caaaacttct cagaaatctt tgaaaaatta
     4261 ggattttata ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggttgctcaa
     4321 aacactgttt tgaggttgta gatgaaactg acgaagtcag taaccatacc tacggcaagg
     4381 tgaagctgac gtggtttgaa gagattttag aagagtatta atgatagata aagtggtcag
     4441 gaacttactc ctgacctttt tcctttgcaa aatgacaaaa atcataaact ttttgacaac
     4501 tatacttgtc aaaaagaaaa agatgtgtta caatgtaagc aagttaagag aaaagaagaa
     4561 aggaaacgca gaaatgtcga gattattaca agaaatgatt ggaaaggaac caattataac
     4621 gggagtgtat attgggccag ataactggga agttgtggat gttgacgagg aatgggtcaa
     4681 actacgtagt gttgataaaa aggggaaaga aaaattcaag ttgcaacgta ttgaagatat
     4741 ccaaaccgtt gaatttgacg gagagtaggt gtgtaacatg caactaaaaa atcgtctaaa
     4801 agagcttcga gctcgcgatg gtctcaatca aaccgaccta gccaaactgg caggggtttc
     4861 cagacagacc attagcctac tagaacggga tgagtacacc ccatccatta tcattgccct
     4921 gaaaatatct caaattttca acgaaacagt cgaatcggta tttcgtttgg aggaggacga
     4981 gtgatgaaca agtataaagt gatttattat gtagtggtca tagctttatt agtcagcgta
     5041 tttctactga ttgggatgga cctaagctgg tttaatccct atcaaagcga ccaatttgtt
     5101 tgggtctact ttgctctcat cccagtaact gaatggattg aaaagaaatc caaaaatcta
     5161 gcaagtgaaa aaggagaatg aatatgaaaa agaaacgtag attgttattt ttgatgtcta
     5221 ttgtcttggg gggttcttgg gcatgtttgt agggatgttt aaggcacgtg tcgaatccca
     5281 cgaaattatt ttagatgtaa aagccttgat gccatggata tcagctattt gtttactgat
     5341 aggtttcatt agtatgtttt tgactttcaa tttcttaaag aaaagcagaa aatttcattc
     5401 cttgtatcaa gaggaaatgg atgacgatct gaatgaaacc tattatgtgc aaatgtatcg
     5461 gaatcttgag tttggaacca ttgcttttaa tattacaggt gtagcgattc cattggctat
     5521 ttttatttca ttaagtgagg tgattatatt gcatacaaac cctcaaacat ttttcctttc
     5581 tttcttactc tttgtggtat tcttagtcgc tcaaaaatct ctttttaaaa ccattgcgat
     5641 tgttcgtcag tttgatttgg aatttttcgc tacaccaaag gatgtcttga actatataaa
     5701 ttcttatgat gaaggggagc gtcaggctaa tttggaacag agttttcgaa ttttattcca
     5761 attacaccaa tatgtcttac cagccttata tatttttctt attatcattt ctttcttgac
     5821 aggagagatt cagttactag ctttcttgct tgtaggagcc atccatgttt atatcaatgt
     5881 gatgcagtta cctatggtaa aacgttattt caaataaagg agttatctat gaaattactt
     5941 aaaaaccttg gctggattct tctagccctt ctatcctttt tatttatcta tggctttatt
     6001 caggggctcg cgactgcgtc gcttgcttta ggcgcttcac cctatgctgt tactctactc
     6061 tatgtggcct tggctggagt atatgtgtac ggcatttaca aatggtatca gaaggctcct
     6121 gtttatattg agaagagcgg ctttaaccga tttatttggc ttcctgcctt ggtttggttc
     6181 ttatctctgg tcgttcaatt cttcttgcca gatgatcctt cagtaaatca acaaatagcg
     6241 acagacttga ccttgtctca accacttttc tcattctttg ctgtggttat ttttgctcct
     6301 ttgacggaag agattgtttt tagagggatg ttagcacgct atctctttcc taagcaggac
     6361 aatagtaaac gaaccctgat ttttcttctg gtatctagtc ttctatttgc cttgattcat
     6421 tttccaggtg atgtgcaaca attttttgtc tattttagcc ttggttttag tttgggtttg
     6481 gcttacatta gcagaaaagg tctggtctac agtatttctc ttcacgcttt gaataattta
     6541 gtcggctttt tgatgattct catgctataa tagagtcagg aggtcacatg aaacgagtaa
     6601 ttttagtagc agtgattcag gcagtcattc tatttttcat cattggagcg ctagcttatg
     6661 ccttcaaagg cgatttcttc tataactatc tagcagttgt ctttgctcct attgcaggtg
     6721 tactgcgttt tgggacggct tacataacgg aaattgtctt gcctcgaaag gcagccgaaa
     6781 tcgctgaaaa gcgtaaagca ggcaaaaatt caaaataaaa gagtccggtg aagttcatcg
     6841 gatttttgta ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggttg
     6901 ctcaaaacac tgttttgagg ttgtggatga aactgacgaa gtcagctcaa aacatggttt
     6961 tgaggttgta gatgaaactg acgaagtcag ctcaaaacat ggttttgagg ttgtagatga
     7021 aactgacgaa gtcagtaacc atacctacgg taaggcgacg ctgacgtggt ttgaagagat
     7081 tttcgaagag tattagcgct aatttttagg gctttcatct gacttttaaa gactggcaaa
     7141 cttttctgat gattttcatg aagagcctgc gcttttatgg taaaatagta acagaataaa
     7201 agaggagaga aataatgaaa cgtagtatgt atgctggtcg tgttcgtgag gaacacatcg
     7261 gacaagaaat agccttgaaa ggatgggttg gccgtcgtcg tgaccttggt ggtttgatct
     7321 ttatcgatct tcgtgaccgt gaaggaatca tgcagttggt tatcaaccct gaaaaagtat
     7381 ctgcagaggt tatggcaaca gctgaaagcc ttcgtagcga atttgttatt gaggtgactg
     7441 gtcaggtcgc tgcgcgtgag caagccaatg ataagttgcc aactggtgcg gttgagttaa
     7501 acgtgacagc tcttattgtg cttaacacag ctaagacaac accatttgag attaaggatg
     7561 gcattgaggc aaatgacgat acacgtttgc gttaccgtta ccttgacctt cgtcgtccag
     7621 aaatgttgga aaatcttaaa cttcgtgcca aggtgaccca ctctatccgc aactatttgg
     7681 atgagttgga gtttatcgac gtggagacac cattcctttc taagtcaacg cctgaagggg
     7741 cgcgtgatta tttagtgccg tctcgtgtta ataaggggca tttttacgct cttcctcaaa
     7801 gtccacaaat cacgaaacag ctcttgatga atgctggttt tgaccgttac taccaaatcg
     7861 ttaaatgttt ccgtgacgag gacttgcgtg gagaccgcca gcctgaattt actcaggtcg
     7921 acttggaaac gtccttcctt actgagaaag aaatccaaga tattacagaa ggcttgatcg
     7981 cgcgcgtgat gaaggaaaca aaaggcatcg aagtaacgct accgttccct cgtatgaaat
     8041 acgatgatgc tatggctctt tacggttctg acaagccaga tactcgtttt gacatgttgc
     8101 ttcaggactt gacagaagtg gtcaaaggtg tagactttaa agtcttttca gaagcacctg
     8161 ctgtaaaagc gattgtggtc aaaggagctg cggacaacta ttcacgtaaa gacatcgaca
     8221 agatgacgga agtagccaaa cagtatggtg ccaaaggtct tgcttgggtc aaggtggttg
     8281 atggagaatt aaacggacca gttgccaagt tcttgactgg tatccaagaa gaattgacaa
     8341 cagcgcttgt tcttgaagat aaggacttgg ttctctttgt ggcggatacg cttgaagtgg
     8401 ctaatgcaac actgggtgcc cttcgtggac gtattgctaa agagcttggc ttgattgata
     8461 atgataagtt caacttcctt tgggtggttg actggccgat gtttgaatgg tctgaagaag
     8521 aaggccgcta catgagcgcc caccatcctt tcacacttcc acaggaagag actgctcacg
     8581 aattagaagg tgatttggct aaggttcgtg ccattgctta cgatatcgtc ttgaacggtt
     8641 atgagcttgg tggtggtagc cttcgtatca accaaaaaga ccttcaagaa cgcatgttca
     8701 aggctcttgg tttctcaact gaagaagcca atgaccagtt tggtttcctt cttgaagcca
     8761 tggactatgg tttcccacca cacggtggtt tggctatcgg gcttgaccgt tttgtcatgt
     8821 tgcttgctgg agaagaaaat atccgtgaag tcattgcctt tcctaagaac aacaaggcaa
     8881 ctgacccaat gacacaagct ccatcaacag tcgctctcaa acaactagag gaactcagct
     8941 tacaagtaga agaagatgaa acaaacaaaa cgaattaagc ggtggcgcta ttatctgcgc
     9001 cgctttgctt atcagataaa aattttacgt gtcttacaaa gtatctctcg agaaaagtat
     9061 gatgagaaga tttcggcctc tctggtctat ggttttttat cagcagtagc agttaatttc
     9121 tttttccaac cagggcatgt gtattcgagt ggtgcaacag gtctggcaca gattatctct
     9181 gccttgagta atcactggtt tggttttcat attccgattt cgctaagctt ttacgccatt
     9241 aacttccctt tgatggtctt agcttggtat cagattggcc ataagttcac cgtctttacc
     9301 tttatcacgg tatctatgag ttccttcttt atccagtttg tccctgtggc aaccttgaca
     9361 gaggatccca ttatcaatgc cctttttggg ggtgttgtta tgggtttggg gattggtttt
     9421 gctcttcgaa acaatatctc cagtggtggg acggacatcg tcagcctgac tattcgtaag
     9481 aaaacgggta agaatgtcgg tagtatttct ttcttggtaa atggaactat catgctgata
     9541 gcaggtttga cctttggttg gaaatacgct ctttattcta tgattaccat ctttgtctct
     9601 agccgtgtga cagacgcagt ctttactaag caaaagcgta tgcaggccat gattgtgaca
     9661 aatcatccag agaaggtaat tgaaaaaatc cataaaaaat tgcaccgcgg agcaaccatg
     9721 atccacgatg cagaaggaac ctataatcac gagagaaagg cagttttaat cactgtcatt
     9781 acacgtgcag agtttaatga atttaaacag attatgacac aagtggatcc aagctccttt
     9841 gtctctgtct cggaaaatgt tcatattcta ggaagatttg ttgagataga taattagtga
     9901 ttaatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttgccgt atatatgtta
     9961 ctgacttcgt caattctatc tgcaacctca aaaccatgtt ttgagcaacc tgcggctagc
    10021 ttcctagttt gcactttgat tttcattgag tataaaaaga tcttgggaaa agactcaatt
    10081 tcagtagaaa aggaagtaaa tcttcccaca ttaaaacgca tagtatcaag ttttttcaat
    10141 acctgatact atgcgttttt gcttttaacg actttttgcc cagtctctta tttttcgata
    10201 attttgtggg cgatcaattg acggtaacaa atttgtttat tgtttttatt atcattaata
    10261 atctggagaa tagtttcaag ggaaacacga ccaagctcta aactattgat atcgacatag
    10321 gctgccaagt tgagcttggg attaaccgag tcaaagctga gaacagggac atccagctgg
    10381 tgtttggcaa tatagttaca aacaccttca gctaggaggc tatcggttgt gatgatagca
    10441 tcaatttgtg gatcgtgctt gaataatcgc ttgctaaatt tatagccctt ttcttccaga
    10501 aactcgtcgg caaagtagat gcgattgttg tcagtggtaa gtttgtaatg tttaagcgcc
    10561 tgttcatagc ctgttaaacg gtctttggtc acgaagagct ttttacttcc tccgataaag
    10621 gcaatgcgtt tgcagccttt tttgatgaaa tattcagtcg catcaaaacc agcttgaaca
    10681 ttgtcgttgt cgacaagtgg gatgaaagga gatagagatt tacctaagat aaggaagggg
    10741 aactgttctt ctgcgacgag ttttacgaga gggtcttctt cttgggcata gagaaagatt
    10801 agcccatcta cacgcttgcc gtagaccatt tgtgaaatag cgttgagacg ctccttctca
    10861 tctttccctg ttgctatctg aatggcatag tggttttcag atgcgacttg agagatgcca
    10921 cgtagaaccg atggaaagaa aggattctgg tagaaggcgt ctgagtcatc aggaagaact
    10981 aatccgataa cctgagtata gctgcttacc aagctacgag cgttgaggtt tgggtggtag
    11041 ttgagttcct tcatagcttt gcgaacgcgt ttttttgttt cgtcgctaat ggttgattta
    11101 ttttgaataa cacgggttac ggttgaaggc gaaacaccag cagccttggc cacgtcttta
    11161 atcgtaacgg gcataaaaat ctcctattta tggtaatttg gatcacggaa atgtgtttta
    11221 taaaagatag tgaccagata cagaacaaaa agaatatttt gtacagtaat cagggttgtc
    11281 atattttggc caaataatcc caaaataagt gtaatcagag tcggcaatcc taaacagttc
    11341 aagataaagt gatagcactc tttaaaggtt ctaaatgaaa agaggcgtga tttcttagtg
    11401 atataaagga gaagactagc tcctagagag acgataaaga aattcaaacc aaagaggaag
    11461 ctcgcaccga gaactaggaa gaggctgata tagacacgat tttgttggta ccagtcttta
    11521 gaaattgctt gggtcaagct gtctttgctt ttgaaactct cagtctgaat ggctcggtaa
    11581 gagatgcggg tcagttcctt gctttccttg ctgatgacta gctcatttgt atcgaaatgc
    11641 agttgcaagt ccttaggtaa ttccttgatt tgacttggac caatcacaac agaaggggct
    11701 tgactagctg ttccagtata agttaatgtg ccatcgacaa ttgtagcatg ttcagagaga
    11761 tcctggacaa cctcatttgt cagaggttca tagacattat cgataaaagt ttctagcgga
    11821 taggtctcct gggagctgtt ttggatagca atgggtacca tagacaagct gataaggaag
    11881 atactggtaa agagaagttg aaaccagttg agctcgaaac gtttggacag gggcttacga
    11941 aacccccaaa tacttgaaaa ataggaaaat ggatatggaa gcataggtat ctttctaaaa
    12001 ggtgttttct atatgagtat tattatatag agaaatgcgc tttatttcaa gtctaggaga
    12061 aaaattgctt gctacaagga tattatttac agtgacaatt gctaataatc aatgaaaatc
    12121 aaagtgcaaa ctagccacag gttgctcaaa gcacaacttt gaggttggag ataaagctga
    12181 cgtggtttga agagattttc gaagagtata aaatgaaaaa gggtggcggg gataaattat
    12241 cccttgtcgc caccacttgt aagtcctgaa acaaagttct tttgtaggaa gaagaagaga
    12301 atacagattg gaagggcgat gaggatagca cctgctgaga agtaggcaat cttcaagttt
    12361 ttcgcattgt taacgaaggt ttggagacct acggcaacag taaagtattc tttctcacga
    12421 agcaagaaac tagagaggat gtagtccccg aaaggtccca tgaaggccca gagagcttgt
    12481 acggcaacca ttgggcgaac aagtggtaga acaatttgcc agaagcggcg gaagtgtcct
    12541 gcaccgtcta gttttgcaga ttcgtctaaa gacattggca ctgtatcgaa gtagcctttc
    12601 atgagccaag cattcatcgg gataccacca ccaacgtaga ggaagatgag gaaccagttg
    12661 tggttaaggg cgttcaacat aagcgccata acgaagaagg ctgtcaaagc ggccatagtt
    12721 ggcaccattt ggatgatcaa gaagaagacc aaactttgtt tacgagccaa gaagttgtaa
    12781 cggctgtaag cataaccagc aagtacgatg atacttgttt gaacagccat ggtaattaag
    12841 gcgataatca aagtgttgag gtaccaagta ccgtacaagg tttcagtgaa gaggccttta
    12901 aagttatcaa aattgaggtc gatattagta tctagtttaa aggctgagac gttacctgct
    12961 ttaaaggctg acataatggt aatcaacagt ggatagataa ttacaattga tagaccaatc
    13021 aggtaaaggt aagtaaggct ttgagtcagt ctacgtttga gtttaattga gttattcatc
    13081 ttagacgtcc tccatatcaa atgcgtgtag tttcttgaat gcgatcatag agattgagat
    13141 gacaatgata gagataatca aggtaacagc tgccgccatt gagtattgag gagatgtacc
    13201 tgttgtcaaa cggtagatcc atgagatcaa gatatcggtt gaaccagctc cacctccgac
    13261 actaccaggt cctccaccat tgaagaggta catgatagag aagttgttaa agttgaaggt
    13321 gtattggcta atcaaagtag gtgccgcaac agccaaaatc attgggaaag tgatgttgcg
    13381 gaatttttgc caagcgttgg caccgtcaat ataagctgct tcgtaaaggt cgttaggaat
    13441 agattgcaag atacccaaag tcaaaacgta gatgtatggg aatccgagcc aaccttgcat
    13501 cataatcaag gcaatcttag tccaagttgg gtctgttttc caaggaataa gagctccatc
    13561 aaggaaagga aggaatttag ccaagattgg caatacttga gtgttgatag caccgacact
    13621 atcgttaaac atatttgaga atgtcaagat agtgatgaag gctgggacag cccaaggaag
    13681 aaggaaaata acaccaaaga tacgttttcc tttgataaat ggttggttgg caatgatagc
    13741 tgtgaagata ccaattacga tttgtaaagt agaagctgcc aaagcccaaa tgatagtcca
    13801 agaaagaaca gaaccaaagg cagaacggaa ggtactcaag ctccaaatgt ttgtaaagtt
    13861 ggtcaaacca acccagtcca acaacttgtt tggtggcaag tgttggaagt cgtagttggt
    13921 aaaggcgatc atcaaggtta cgataactgg gaagataatc gcgaaggtca tggcaacata
    13981 agatggaatg atcaagaggt aagggaagcc attttcataa atccctttga tcatgtcttt
    14041 gagtgtgcgt ggaactggaa ttccattgtt aatgcgtttt gcaatcgtat gtgcatcttt
    14101 gatatttgag aaataaaaga gtacataaac gattacaaag attagatgga aggcaccacg
    14161 aatcagcata aagagggaat tatcacgacc tggtttgtca ccaagagtga tgaggttgct
    14221 caattcaggg gttgcaagtg ctaggaagta aaggacaaat acgatggtta caccaaggaa
    14281 gataaaacct ttggcttttt gtttattgta aatctgtcct aacccaggaa tgatagacag
    14341 cagggctgct ttactaggtt gttgcttttc catattaact cctttcatag gatactactt
    14401 ttttataaga aagctaaatt atttgtgtct ctattgataa attcaaaggg ggatttgatt
    14461 tccacccccc ttgaacaaat tttttattca ccaaattttt gtttgattgt ttctttgatc
    14521 aatgttacag catcgttagc agctgtttta gcatcttttt gaccacttac agcatcaaag
    14581 agcatatttt tcgctggatc ccaaactgca gacatttgag agatgtttgg cagtggttga
    14641 gtgttcttga actgtttgat aacagctgtt gtcaactcat cgtttttacc ttcagcgtat
    14701 gaacgagcct cagtattagc tgggatttcg ttagtcttat catataatac tttttgttgt
    14761 tcagttgcaa caaggaagtc tacaaatttt tgagaagctt caaggttctt aacggcttga
    14821 ggaatgaccc aagctttacc accaccgaat gcagcatatt cttttccatt tggaagagtt
    14881 gggatagttg caactccgta gtttacttta gcatctttaa aggcttgagc tttccaaggt
    14941 ccgtcgatga tagcagctgt tttaccttct tggaattgag tttggattaa gtttccagca
    15001 ccttctgtat cttgcatacc tttaggccat ttttcgtacc aagatttagc gtagttgata
    15061 cctgcgatag aaccgtcgtt tgcaagaccg atgtctttag cgtctttacc gttttggcca
    15121 aagacgtaag caccgttacc ggcaagaagt ccatatgtat agtagaagtt tgtccagtca
    15181 gctaggaagg cagtagtttt accatcttca ccagcgaatg cgtatttgct atctttagca
    15241 aggttttcca agtcagcaaa tgtttttgga gcatctttca ccaagtcttt gttgtagtac
    15301 ataacaagtg actcgataac ggcaggagca ccgtaaactt taccattagc agctgttaca
    15361 agagatttag ttgtgtcgtc tgttttagca ccatcgctca atttcacttc tgaaagttgt
    15421 ccgtcagaac caaggctacc tacacggtcg tatggagcca tcataacatc agggacatta
    15481 ccagattggt tgtcaagaga aagtttatca agacctccta gagcatcacc agttttaaga
    15541 gtgactttta ctccagcttc tttttcataa gctttagcaa cctcttcaat atagctctta
    15601 tatccctcgt ctacatatac agtgagttct ttgacttcag atgaaccaga atcagcaggc
    15661 ttatcagcag ttttgcttcc gcaagctacc aaaagcaagc tagcaagtgt aacagttcca
    15721 agcaccgcag tgctcttcat aaatttagat gacatagtgt attcctccca aagaatagca
    15781 agttttattg ataaggaaac gcaaacgttt tcctttatga gcttagtata gcacaaatag
    15841 aaaacggttg caagtatttt ttgtaaaaat tttaaaaaat ttttaagctt gatttgatag
    15901 cataattttg cattttaata gaagaaaagt atgaaataga taagaataca gtatttttaa
    15961 taaaaatata tggaatctgt ctaaagaggg aaatcaggag gggctacctc cctgtttcta
    16021 atccctatct attttctata gacgtttgtg ctttgttgca tataaattca agctccctaa
    16081 ggaggttttg tactttgtag actgtctcgt gagagtcaaa ctttaggatt agatagtttt
    16141 aagttatctt tgctaaaatg agttagtctc cttaaaaata atcaaaaaag ttttttaaaa
    16201 acgcttgcaa ttatgcttga aaaggagtat acttataagt aacgcaaacg tttgcgtctg
    16261 caaaatacgc aacgttccat tattttaaca cacgaggtgc tattatgaaa aaacgtcaaa
    16321 gtggtgtgtt gatgcacatc tcttctcttc caggagctta cggaatcgga tcatttggtc
    16381 aaagtgctta cgacttcgtt gatttcttgg tccgtacaaa acaacgttac tggcaaatcc
    16441 ttccattagg agcaactagt tacggggatt ctccttacca atctttctca gccttcgcag
    16501 gaaacactca ttttatcgat ttagatatct tggtggagca aggtttgttg ggagcgagtg
    16561 accttgaagg agttgacttt ggtagcgatg cgtctgaagt tgactatgct aaaatctact
    16621 atgcacgtcg tcctctttta gaaaaagcgg tgaaacgttt ctttgaagtc ggagatgtta
    16681 aagattttga gaaatttgct caagacaacc aatcatggct tgagctcttt gctgagtata
    16741 tggctatcaa agagcatttt gacaatcttg cttggactga atggccagat gcagatgctc
    16801 gtgctcgtaa agcttcagca cttgaaagct atcgtgagca attggcagac aagttggttt
    16861 accaccgtgt gactcaatac ttcttcttcc aacaatggtt gaaattgaaa gcttacgcta
    16921 acgacaacca cattgaaatc gttggggaca tgccaatcta cgtagcggaa gattcaagtg
    16981 atatgtgggc aaatccacat ctcttcaaaa cagatgtcaa tggtaaggct acttgtatcg
    17041 caggatgccc accagatgag ttttctgtaa ctggtcagct ttggggtaac ccaatctatg
    17101 actgggaagc aatggacaaa gacggctaca aatggtggat tgaacgcttg cgtgaaagct
    17161 tcaaaatcta cgatatcgtt cgtatcgacc acttccgtgg cttcgaatct tattgggaaa
    17221 tccctgctgg ttccgataca gcagcacctg gtgagtgggt gaaaggtcca ggctacaagc
    17281 tttttgcagc cgttaaggaa gaacttggtg agctaaacat catcgcagaa gaccttggct
    17341 tcatgacaga tgaagtgatc gaattacgtg aacgtactgg cttcccagga atgaagattc
    17401 ttcaatttgc cttcaaccca gaagacgaaa gcattgatag cccacacttg gcacctgcta
    17461 actcagttat gtacacagga acacacgata acaatacggt tcttggttgg taccgtaatg
    17521 agattgatga tgcgactcgt gagtacatgg ctcgttacac gaaccgtaaa gaatacgaaa
    17581 cagtggtaca cgctatgctt cgtacagtat tttcatcagt tagctttatg gcaattgcaa
    17641 ctatgcaaga tttactagaa ttggatgagg cagctcgtat gaacttccca tctacccttg
    17701 gtggaaactg gtcttggcgt atgactgaag atcaattgac accagctgtc gaggaaggtt
    17761 tgcttgactt gacaacaatt tatcgccgaa ttaatgaaaa tttggtagat ttaaagaaat
    17821 aagacaataa tcaggagaca actaaacatg ttatcactac aagaatttgt acaaaatcgt
    17881 tacaataaaa ccattgcaga atgtagcaat gaagagcttt accttgctct tcttaactac
    17941 agcaagcttg caagcagcca aaaaccagtc aacactggta agaaaaaagt ttactacatc
    18001 tcagctgagt tcttgattgg taaactcttg tcaaacaact tgattaacct tggtctttac
    18061 gacgatgtta aaaaagaact tgcagctgca ggtaaagact tgatcgaagt tgaagaagtt
    18121 gaattggaac catctcttgg taatggtggt ttgggacgtt tggctgcctg ctttatcgac
    18181 tcaattgcta ctcttggttt gaatggtgac ggtgttggtc ttaactacca ctttggtctt
    18241 ttccaacaag ttcttaaaaa caaccaacaa gaaacaattc caaatgcatg gttgacagag
    18301 caaaactggt tggttcgctc aagccgtagc taccaagtac catttgcaga ctttactttg
    18361 acatcaactc tttacgatat tgatgttact ggttatgaaa cagcgactaa aaaccgcttg
    18421 cgtttgtttg acttggattc agttgattct tctattatta aagatggtat caactttgac
    18481 aagacagata tcgctcgcaa cttgactctc ttcctttacc cagatgatag tgaccgtcaa
    18541 ggtgaattgc tccgtatctt ccaacaatac ttcatggttt caaacggtgc gcaattgatc
    18601 atcgacgaag caatcgaaaa aggaagcaac ttgcatgacc ttgctgacta cgcagttgtc
    18661 caaatcaacg atactcaccc atcaatggtg attcctgaat tgattcgtct tttaactgca
    18721 cgtggtatcg agcttgacga agcaatctca attgttcgta gcatgactgc ctacactaac
    18781 cacacaatcc ttgctgaagc gcttgaaaaa tggcctcttg aattcttgca agaagtggtt
    18841 cctcacttgg taccaatcat cgaagaattg gaccgtcgtg tgaaggcaga gtacaaagat
    18901 ccagctgttc aaatcatcga tgagagcgga cgtgttcaca tggctcacat ggatatccac
    18961 tacggataca gtgttaacgg ggttgcagca ctccatactg aaatcttgaa aaattctgag
    19021 ttgaaagcct tctacgacct ttacccagaa aagttcaaca acaaaacaaa cggtatcact
    19081 ttccgtcgtt ggcttatgca tgctaaccca agattgtctc actacttaga tgagattctt
    19141 ggagatggtt ggcaccatga agcagatgag cttgaaaaac ttttgtctta tgaagacaaa
    19201 gcagctgtca aagaaaaatt ggaaagcatc aaggctcaca acaaacgtaa attggctcgt
    19261 cacttgaaag aacaccaagg tgtggaaatc aattcaaatt ctatctttga tatccaaatc
    19321 aaacgtcttc acgagtacaa acgccaacaa atgaacgctt tgtacgtgat ccacaaatac
    19381 cttgacatca aagctggtaa catccctgct cgtccaatca caatcttctt tggtggtaaa
    19441 gcagctccag cctacacaat cgctcaagac attatccatt taatcctttg catgtcagaa
    19501 gttattgcta acgatccagc agtagctcca cacttgcaag tagttatggt tgaaaactac
    19561 aacgttactg cagcaagttt ccttatccca gcatgtgata tctcagaaca aatttcactt
    19621 gcttctaaag aagcttcagg tactggtaac atgaaattca tgttgaacgg agctttgaca
    19681 cttggtacta tggacggtgc taacgtggaa atcgctgagt tggttggaga agaaaacatc
    19741 tacatcttcg gtgaagattc agaaactgtt atcgaccttt acgcaaaagc agcttacaaa
    19801 tcaagcgaat tctacgctcg tgaagctatc aaaccattgg ttgacttcat cgttagtgat
    19861 gcagttcttg cagctggaaa caaagagcgc ttggaacgtc tttacaatga attgatcaac
    19921 aaagactggt tcatgactct tcttgacttg gaagactaca tcaaagtcaa agagcaaatg
    19981 cttgctgact acgaagaccg tgacgcatgg ttggataaag tcatcgttaa catttctaaa
    20041 gcaggattct tctcatctga ccgtacaatc gctcagtata atgaagacat ctggcacttg
    20101 aactaatact cttcgaaaat ctcttcaaac cacgtcagct ttatctgcaa cctcaaagcg
    20161 gtgctttgag caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa
    20221 gatacaaatt tatactaata cattttgtaa aaaagcgagt ttcgattgaa attcgctttt
    20281 ttaaatgctg tggatttggg tcaatcttgt ctaaaaatag ggaaatccta gatacagtga
    20341 aggctttaaa tgctggtttt tactgtcttc agccttatat tttttcgtag ttggttacct
    20401 cacatctctt gtattcgctt acataaagta ttataatata attgtaggaa agaaggtgtt
    20461 tttatgatat acacacttaa attggtgttg tttattacct ttcttgtaat aagcttgtta
    20521 cctgataaga tttttggaaa aaataaaaaa atttggaaaa tagtttttgc aatattgacg
    20581 gcagtggcag cattgtcatt tatgtactaa gttattttaa gaatgtaggg aaataaaccc
    20641 tacattcttt ttagtttttt ctgttttcta aattctattt atccaagcga ttcaacattt
    20701 cttgcttctt cgcttcaagt tctgcacgct tttcttcgat ttcggcatgt tttttctcga
    20761 gttcagaaca acttgcacca ttgctaaatt cttttcgcca tcaggagata gggtgagtcg
    20821 acatgtctat tactcaccca aagcagtcct acaaagcagg aattttctgt tacttttttg
    20881 gaaatagtaa cgtttataca gctttgacac ttcgtatcaa agcgccaaac acactccgag
    20941 ggatttacag aaagcagaaa aggaatgatc tggtataaga tcattccttt tctctctttt
    21001 tctttaagta attatataca atgtacgacg aagtcgtcat tgcaatgctg atccaccacc
    21061 taaagggaac tttaaacaac attgataaga taaagaatat aaacaacgaa aatacgttat
    21121 acccaattaa ttttattgta tatctcatga ttaaaagtta atccttccgt tgttaggaat
    21181 ggcatcattt ttatcccata attgtgctaa ataagtcccc ggtgataata aattcatagc
    21241 gaattctaaa gcaacatcat ttacaaacca actacctaga tatctagaaa ttgctgaacg
    21301 aatagcactt tttgctgcat gttttccttt tactttaatt agatttgcaa ggcctgcagt
    21361 agttcctcct aatgctaaag ctattgcagt atctaataga gcacccattt gattaactgt
    21421 aataccttgc caagctgctc taaatggaga gtatgtaggt gggattgtat aatcgccttg
    21481 taattgtcgg ttaattactt ctttgatcca ttgttgtgag acgtctggat gaaaagattg
    21541 gatttcgttt gcaagtgtat tgatttgttc ttctgttaga gaagtgacag gttgaagttc
    21601 catatttgtt tcaatttgtg atacttgttc agaagcgtat acagctgaaa cacttggaat
    21661 cgctgataca attaacacaa ttgacgtcaa aaaaaccgaa ataaatttca ttaatttgtt
    21721 catgagcttt tctccttttt atttgtatct gcttacattt tatcatatac tgttattata
    21781 gtcaaaaaaa tatgctatta tgttaaaaaa atatttttca aaatataaat ggacggattt
    21841 attttggatt ttatttgtta ttttgacctg cctctatatt ggtaaccatg atttgtttac
    21901 tctcaatcat caagaattct cttttcgtgg tagcgtttgg ggtctggtac tggccttata
    21961 tcacttattg ttcattgata agtttgtaat ttcgaatcga aaataaagat tagaactatg
    22021 attgactggc tacttttaat attgattttg gaggaagatt ttgtctctat tatttattat
    22081 tttaaattta tttattttgt ataagatcta ttctttgagg cgggaaaaat cgaaatactt
    22141 gatttatacg gcctatatca tatttggggt aaatgtagta tatggtattc aatggttatt
    22201 aagagaactg atttcaacta tttcccctta atgtgtatgg aaactataac aaaacgcata
    22261 agattaaggt ttgtgtacct gttcttatgc gtttttataa tattgaagat tttcggtaag
    22321 ttttctactt ttgcgaagtc tagtttatac tcaatgaaaa tcaaagagta aactagccgt
    22381 aggttgctca aagtacagct ttgaggttgc agataaaact gacgaagtca gctcaaaaca
    22441 tggttttgag gttgtagatg aaactgacga agtcagtaac catacgtacg gcaaggcgac
    22501 gttgacgtgg tttgaagagt attagaatgc tttcccaacc aaaatctctg cttcgatggt
    22561 aatctctgtc agttggctcc agtcaatctt gctctggtca acgtgaaaga ggagaggagt
    22621 catactgagt agggcttgga gttgttctgc tgtgatagtc ttagtcagag aggcagtttg
    22681 actagatagg atggtaaagt gttcctggaa atgctccttg atatcttggt tagaatactc
    22741 cttgtttgtc agctggtcct gtactctttg acggatttct ttgaggtgat tttcagttgg
    22801 gataaccttt atcaagatac cgtctttgga taaaacgcga cgaaattctc catagttggc
    22861 aggtgagaag atatcaagca gaatatccat gttagcgtct tttataggaa ggcgtgccaa
    22921 gtcgccaacg aaccaattga ctgcccagtt gggttcactt ttagcagcga tttggactga
    22981 atctttggag atatcaaagg catagaaagt tttttcagag tgactttctt gtagtttgcg
    23041 agaatagaat ccttcaccac aaccgatatc caaaattgtt gtggtagttt ttgagcttgc
    23101 aagcaagtca gatacagcat ctaagatagc ttggtaaaag ccggcttcta ggatttgttg
    23161 acggttttga aaattttcct tgtcatagtt agcagattgc ttgatttgag gtgctagatt
    23221 gacatagcca aatttcgcca agtcaaaaga atgacggttg cagcacttga aattagtctc
    23281 taacagagtc agattttctt gacagatagg acaggcaaag gcagtcgcag aagcaaaacg
    23341 ctgaagtttg ggcttgagat ttgtattcat agtttaagtg tatcaaaaga ggcaaatgaa
    23401 agcaacttta ggaataagta gatgggagat tcagtagaaa taaaactaat tctccaattt
    23461 atagaatgaa attgctttta tatctaaatt gctatataat aatgataagg aggaaataag
    23521 tatgttaaaa gaagtattaa ccgttgcaaa agttgcgaaa aaatcttcat tatttttggg
    23581 tggtgtcgca tttggtaccc ttggtttgaa aatcttagca agtaaggaag ctaaaaaagg
    23641 ttattctaaa gctttggcta aggcttacaa gttgaaagac gagctagatg catctgtttc
    23701 tgttgtgaag caacatggag acgatgtctt gcaagatgcc aaatatttgt acgagcaaga
    23761 gaaaaaagaa gagcaattag atagccttat aggtgaataa tatgtctttt aaagtgctac
    23821 atagaggata ccaacatatc cgactatcat cttctttttc acttaccttg gatattcaag
    23881 actatcttcg ttccttggcg agagatgaaa aggggattga gtctatccag ttttacatgg
    23941 atcaacagca ctttactcta cgcataaaag aaggcttttc tgtattagat aatgcagaag
    24001 cctttttaaa aagaattgat aaagggaaag tttctgagtt gatgactctt cccattcgta
    24061 gagaagagag tgcttattct attgtttcag gtgcagcggt taagcgtgta ctttttcgta
    24121 gttttgtgcc gtatcctatt cgctatatat ggacttgtta tcaggctttg ggttatatta
    24181 gagaagccta tcaaacacta gcgcgtaagg aactaactat ggaagtcttg gactgttcgg
    24241 ctattttatt gtctttgttt atgaaccaat ccaagacagc tagcaatatc atgtttatgc
    24301 ttgatttggg gaatcattta gatcagtggt ccttgaaaaa aactgcaaca gatttagaac
    24361 agagtcttct tgcaaaagag agcgatgtat tcctagtaca gggcgatacg gttgttagta
    24421 taaagagttc cgatgttcaa ataggagatg tcttgatctt atctcaagga aatgaaattc
    24481 tgtttgatgg gcaagtagtt tcaggtttag gtatggtcaa cgaaagttcc ttgacaggag
    24541 agagttttcc agttgaaaaa agagagtctg atttggtttg tgcaaataca gtattagaaa
    24601 ctggagagtt acgcattcgt gtaacagata atcagatgaa cagccgtatt ttacagctga
    24661 ttgagttgat gaagaaatct gaagaaaaca agaaaacgaa acaacgctat ttcatcaaga
    24721 tggcggataa agtcgtcaaa tataatttct tgggggctgg gctgacttac ctattgacag
    24781 gttctttttc taaggctatt tctttcctat tggtcgattt ctcctgcgct ttgaaaatct
    24841 ctactcctgt agcttatttg acagttatca aggaggggtt gaaccgtgaa atggtgatta
    24901 aggatggaga tgttctggag aaatatctgg aagttgatac tttcttgttt gataagacag
    24961 gaacaatcac aactagttat cctatagttg aaaaggtgtt accttttgga gactatagtg
    25021 aggaagatat tctcagaatc agtgcctgtc ttgaggaaca catttatcat cctattgcta
    25081 atgccatcgt caagcaagct gagatagagg gaattgaaca tgaggaaatg catgggaaac
    25141 tccaatatat cgcaagcaag gggatcaaat ctcatataga tggccaacca gttcttattg
    25201 ggaattatgt cttgatgcag gatgagcaga ttcatatcag ttcagaacaa aatgctttaa
    25261 ttgaagagta caagagtcac tacaatctct tattcttggc ttatcaaaat gaattgattg
    25321 gaatgttctg cattcatact cctttgagaa aagaagcaaa aacagccttg gataaactta
    25381 aggcacaggg gaaaaaattg attctggcaa caggagacac cttgattagg acagaggaat
    25441 tagtcaaaga tttgcccttt gatcaggtct atacagactt gaaacctgat ggaaaatttg
    25501 agttagtaga gaaactgcag aaagcaggtc acactatttt gatggttgga gatggattga
    25561 atgactcagc ggctctaact ctatcagata tcggtgtggt gatgaatgag agtgcagata
    25621 tttctaagca gatgagtgat atcttattgt tagataatcg tttggatttc ttccaagagt
    25681 tggattcgtt atcatcatct ttgcaaacac tcatcaagaa aaatattcaa gataccgttg
    25741 tcgtaaatag tagtttgatt ggcttcggct tatttaattg gctcagtcct tcaaatctct
    25801 ctatcttaca taatctaaca accttgcgca ttgtcctgcg tagcctgtct attaaaaata
    25861 gatagatgag agttattaac agcaaaaagg agttaccttt ctcgaggtta actcctttgt
    25921 ttatagataa atgttgaata gtttagtaag tcaatacaaa gtattttttc ttcccacgac
    25981 ggataacagt cagttcattt tctaacttat cagcgtcact caagacatag tcaagctctt
    26041 ggatgcggtc gccgtttacg tagatggctc cgttttggac gtcttcacgg gcttggcgtt
    26101 ttgagttaac tataccagat gagacgagca gttccacgat attgttgttt tcgtctgcct
    26161 gtacttggta gtttggcaca ccacgaagtc cttgtttgag ctctttgaca gaaaggtttt
    26221 tgatgtttcc tgcaaagagt tgctcagtga tgttaagtgc ttctttgtag gcttcttctc
    26281 cgtgaacaag tgtaacaact tcacgagcca agactttttg agccaagcgt tcgtgtggcg
    26341 ctgcttcaaa ttgtttacga atatcttcaa tctcatcaag tgacaagaaa gtaaagattt
    26401 tcaagaagcg aacagcgtca gcgtccatca cgttcatcca gaattggtac atttcgtatg
    26461 gagaagtctt ttcgggattg agccagacgg catttccttc tgatttacca aatttcttac
    26521 cagttgcatc tgtgattagt ggaacagtga taacgtgacc agtcttgtcc gccttacgac
    26581 gaagcaattc ggtaccagct gtcatatttc cccactggtc agaaccaccg atttgaagag
    26641 tgacattatg gtcttggtta aggacgaaga agtcataccc ttgcatgatt tggtaagcga
    26701 actcagtgta agaaattcct gtttcgatcc gttttttaac agattcctta ctcatcatgt
    26761 agttgaccgt gaagtatttt ccaatatcac ggaggaagtc aatgaagctg atgctgccaa
    26821 accagtcgta gttgttgacc atgacagcct tgttttcgcc attttcaaag tcaagaaaac
    26881 gagaaagttg tccttggata gacttgaccc agccatctac tgtgtctttt gtttggagac
    26941 tacgttcagc atctttgaag gacggatctc cgatgagacc tgtagcaccg ccaacgagcg
    27001 cataaggttt gtgacctgct agttgcaagc gacgacttgt caagattgcg acaaggtggc
    27061 ctaggtgaag gctgtcagca gttggatcgt agccagtata ataagaaact tgaccttctt
    27121 ctagggcttt acgcaaagct tcttcatcag tcgtttgaaa tatcaaacca cgctctttta
    27181 gctcatcaaa aatgtgcatg tgttttttct cctttttaaa attattgttt ctacctattg
    27241 tatcacaaac ttgggcaata gcctagcaga atagggaaga aagtggctat tttattgaaa
    27301 atttcccttt tgtggtataa tagataaagt gaggaaatcc atgcaaaatc aattaaatga
    27361 attaaaacga aaaatgctgg aatttttcca gcaaaaacaa aaaaataaaa aatcagctag
    27421 acctggcaag aaaggttcaa gtaccaaaaa atctaaaacc ttagataagt cagccatttt
    27481 cccagctatt ttactgagta taaaagcctt atttaactta ctctttgtac tcggttttct
    27541 aggaggaatg ttgggagctg ggattgcttt ggggtacgga gtggccttat ttgacaaggt
    27601 tcgggtgcct cagacagaag aattggtgaa tcaggtcaag gacatctctt ctatttcaga
    27661 gattacctat tcggacggga cggtgattgc ttccatagag agtgatttgt tgcgcacttc
    27721 tatctcatct gagcaaattt cggaaaatct gaagaaggct atcattgcga cagaagatga
    27781 acactttaaa gaacataagg gtgtagtacc caaggcggtg attcgtgcga ccttggggaa
    27841 atttgtaggt ttgggttcct ctagtggggg ttcaaccttg acccagcaac taattaaaca
    27901 gcaggtggtt ggggatgcgc cgaccttggc tcgtaaggcg gcagagattg tggatgctct
    27961 tgccttggaa cgcgccatga ataaagatga gattttaacg acctatctca atgtggctcc
    28021 ctttggccga aataataagg gacagaatat tgcaggggct cggcaagcag ctgagggaat
    28081 tttcggtgta gatgccagtc agttgactgt tcctcaagca gcatttttag caggacttcc
    28141 acagagtccc attacttact ctccttatga aaatactggg gagttgaaga gtgatgaaga
    28201 cctagaaatt ggcttaagac gggctaaggc agttctttac agtatgtatc gtacaggtgc
    28261 attaagcaaa gacgagtatt ctcagtacaa ggattatgac cttaaacagg actttttacc
    28321 atcgggcacg gttacaggaa tttcacgaga ctatttatac tttacaactt tggcagaagc
    28381 tcaagaacgt atgtatgact atctagctca gagagacaat gtctccgcta aggagttgaa
    28441 aaatgaggca actcagaagt tttatcgaga tttggcagcc aaggaaattg aaaatggtgg
    28501 ttataagatt actactacca tagatcagaa aattcattct gccatgcaaa gtgcggttgc
    28561 tgattatggc tatcttttag acgatggaac aggtcgtgta gaagtaggga atgtcttgat
    28621 ggacaaccaa acaggtgcta ttctaggctt tgtaggtggt cgtaattatc aagaaaatca
    28681 aaataatcat gcctttgata ccaaacgttc gccagcttct actaccaagc ccttgctggc
    28741 ctacggtatt gctattgacc agggcttgat gggaagtgaa acgattctat ctaactatcc
    28801 aacaaacttt gctaatggca atccgattat gtatgctaat agcaagggaa caggaatgat
    28861 gaccttggga gaagctctga actactcatg gaatatccct gcttactgga cctatcgtat
    28921 gctccgtgaa aatggtgttg atgtcaaggg ttatatggaa aagatgggtt acgagattcc
    28981 tgagtacggt attgagagct tgccaatggg tggtggtatt gaagtcacag ttgcccagca
    29041 taccaatggc tatcagacct tagctaataa tggagtttat catcagaagc atgtgatttc
    29101 aaagattgaa gcagcagatg gtagagtggt gtatgagtat caggataaac cggttcaagt
    29161 ctattcaaaa gctactgcga cgattatgca gggattgcta cgagaagttc tatcctctcg
    29221 tgtgacaaca accttcaagt ctaacctgac ttctttaaat cctactctgg ctaatgcaga
    29281 ttggattggg aagactggta caaccaacca agacgaaaat atgtggctca tgctttcgac
    29341 acctagatta accctaggtg gctggattgg gcatgatgat aatcattcat tgtcacgtag
    29401 agcaggttat tctaataact ctaattacat ggctcatctg gtaaatgcga ttcagcaagc
    29461 ttccccaagc atttggggga acgagcgctt tgctttagat cctagtgtag tgaaatcgga
    29521 agtcttgaaa tcaacaggtc aaaaaccagg gaaggtttct gttgaaggaa aagaggtaga
    29581 ggtcacaggt tcgactgtta ccagctattg ggctaataag tcaggagcgc cagcgacaag
    29641 ttatcgcttt gctattggcg gaagtgatgc ggattatcag aatgcttggt ctagtattgt
    29701 ggggagtcta ccaactccat ccagctccag cagttcaagt agtagttcta gcgatagcag
    29761 taactcaagt actacacgac cttcttcttc aagggcgaga cgataattct ctaaatgaag
    29821 tggccaatca atggattgcc acttttttct tttcgtgtta caataagggt atgaatcagt
    29881 atcagaaaaa gattgttaac ggaaaaattt attcgctcct atccggctta atatggggaa
    29941 tctgtggaat tttaggagag tacttcttta ctcattatca ggtgtcttcg ggctggatta
    30001 cctctatgcg tttgacactg gcagggagtc ttgtactcat ttggtctgca atacaattaa
    30061 aatcgcaagt gctagatatt tggcgagaca agaaaaatta cctgcccttt ttagcctatg
    30121 ctattttggg gattttttca gttcagtatt ttttctatct ctgtgtagaa tactcaaatg
    30181 ctacgacagc aactatttta cagtttatta gccctgtctt tatcctcttt tacaatcgct
    30241 tggtttatca aaaacgagcg tcaaaaagcg ctgttttcta tgttttggtt gccatgctgg
    30301 gtgtttgctt gatggcgaca aagggagatc tctctcagtt atccatgacg ccgctagctc
    30361 ttataacagg tttgctgagt gccatgggtg ttatgtttaa tgttatcttg ccccaacctt
    30421 ttgctaagcg ttatggtttt gttcctacgg ttgggtgggg gatgattttg gcaggtttgt
    30481 ttagcaatgt cctctcgccg gtttatcagc tttcctttac tcttgatatt tggagtatct
    30541 tgatttgcct cattatcgct ttctttggaa cggcttttgc ttttttcatt tccatgaagg
    30601 ctgtgtcctt ggtttctcct ttggtggttg ccgttatcag tgccagtgaa cctctctctt
    30661 ctgctctctt gagtgttttg ttcttaggat tagtagtgga ttggtccctc cttctagcta
    30721 tagccttgat tattttaccc atgatatttt tgtctataga agaagcgaaa gaaagtagat
    30781 aaaaagtctt ttcttaattc taaaagtgtg ctatactaga atagtcaata aaacacgggg
    30841 agatagttgt gaagagtgtt tttaggttgt atcggtaggg gcttgctttt accgacagca
    30901 cgttttatct cacaacccta aaaaatcata cctaaaaaca gacaaaaagg tttcaaattt
    30961 gaggcctttt ttggtagaat aggtatcatt ataacgaacc aggaggcacc tatgactgct
    31021 acaaaaatga acgctcaaga aattatccaa tttatcgcca atgctgaaaa gaaaaccagt
    31081 gtcaaagtaa cctttgaggg gcaactcgca actgctgtgc ctagctctgt tgtcaaacta
    31141 ggaaatgtcc tattcggaga ctggaaggac gtggctccgc ttcttgaagg tttggtagaa
    31201 aatcaagatt atgttgtcga gcaagatgct cgtaattctg cagttccttt gctagataag
    31261 cgtgctatca acgctcgtat cgagccaggt gctattatcc gtgaccaggt ggaaattggt
    31321 gacaatgctg ttatcatgat gggagctgtt atcaatatcg gtgctgaaat cggtgctgga
    31381 accatgattg acatgggtgc catccttggt ggccgtgcca tcgttggaaa aaatagccac
    31441 gttggtgcag gtgcagtttt ggcaggtgtg attgagccag ctagtgctga accagtccgt
    31501 gtcggagaca atgttcttat cggtgctaat gcagtggtta tcgaaggagt ccaaatcggt
    31561 agtggttcag ttgtcgctgc aggagctatc gttacccaag atgtcccaga aaacgtggta
    31621 gtagcaggtg ttccagctcg tatcatcaaa gaaattgatg cccaaaccca acaaaaaaca
    31681 gcgctagagg atgcgcttcg taccttgtaa ttgtaaaagt aaaaaagagg cggaaccctt
    31741 tttccagcct ctttctgcta tatcggagga cagatagatg ttagatttga ttcagactag
    31801 acgagcttta caccagattc cagagattgg cttggaggag ttcaagactc aggcttattt
    31861 gctggatgtg attgagaaat tgactacggg caaggatttt gttcaaattc gtacttggcg
    31921 gacagggatt ttggtctacc tgcagggaag tcagccggag cgaaccattg gttggcggac
    31981 agatattgat ggtctgccta tcgtcgaaca aacaggtcta ccttttgctt ctcaacacca
    32041 aggtcgcatg catgcctgtg gtcatgattt tcatatgacc attgccttag gctgtcttga
    32101 gcgcgccctt gaggagcaac ccaagaataa tctgctcttt ctatttcagc ctgctgaaga
    32161 aaatgaagct ggtggtatgc tcatgtatga ggacggtgct tttggagatt ggttgccaga
    32221 tcaattctat ggtctccatg ttcgtccaga tttgaaagtc ggccagattg cgactaatac
    32281 tcatacactc tttgcaggaa cttgcgaggt gaagatccgt ttcaaaggca aaggtggcca
    32341 cgcagctttt cctcatgaag ccaatgacgc cttggtggcg gctagttact ttgtgaccca
    32401 agtgcagtca gttgttagcc gcaatgtcaa cccaatcgag ggagcagtgg tgaccttcgg
    32461 cgtttttcaa gctggaacca ccaacaatgt catcacagac acagcttttt tacatggaac
    32521 tattcgtgcc ttgacacagg acatgagtct cttggtgcaa aagagggtaa aaacagttgc
    32581 agaaggggtt gcagctgcct ttgatatgga agtcgaagtg gaactcaaac aaggtggata
    32641 cctacctgtt gagaacaatc cagccttggc gcgtgaactg atggacttct ttgacgaaaa
    32701 agacggaatc gagttgattg atatcgaacc tgctatgaca ggcgaggact ttggttatct
    32761 cctttcaaag gttgatggcg tgatgttttg gctaggtatc gatagtccct acgctcttca
    32821 tcaccctcaa atgagtccta aggaagaagt cttagctatt ggggtggctg cggtgtctag
    32881 tttcctgaaa aagaaggcag cagaatagag ggcttgtcta tgaaatcgga attacgcaag
    32941 caagtcttgc atgaaatgaa ggctttatct caagaacaaa aacaggctat agaccaagct
    33001 ttaaccgagc gaattttaca acaccccttt tatcaagaag ccaaggtcat cgcaacctac
    33061 ctctcttttt ctcatgagtt tcaaacgcgg gaactgattg agcaggcgct gaaggacggc
    33121 aagaaggttt tgacacctaa gacctatccc aaggggcgca tggactttgt agtctatgat
    33181 ccgcagcagt tggtaaaaac tgcctttgcc ttactggagc cacagggaga tttggaagtg
    33241 gtggatgtat ctcagattga tttgattcat gttcctggcc tggcttttac gacggatgga
    33301 tatcggattg gatatggtgg aggttattat gaccgctatc tggaacattt ttctggtcat
    33361 actttgagta cggttcatcc ttgtcaaatt caggacttta tacctgaaaa ccatgatatt
    33421 cctgttcagg aggtattaat tgatgaagga aatctttgat agacgttacc ctgtgacgag
    33481 tttcttcctc ttagtgacgg ccttggtatt tttactaatg ttggtcactg caggcggaaa
    33541 ctttgacagg gcagatacat tatttcgatt tggagccatg tatgggccag ctattcgcct
    33601 ctttcccgag caggtttggc gtctcttgtc tgccattttt gttcatattg ggtgggaaca
    33661 tttcattgtt aatatgcttt cactttatta tcttggaagg caggtagagg agattttcgg
    33721 ctctaagcag ttcttttttc tctatctctt atcaggaatg atgggcaatc tctttgtttt
    33781 tgtatttagt cctaaatcct tagcagcagg cgcctctacc tctctttatg ggctatttgc
    33841 cgcgattatt gttcttcgct atgcaactcg caatccttat atccaacagc tagggcaatc
    33901 ctatctgaca ctttttgtgg ttaacattat tggaagtgtt ctgattccag gaatcagcct
    33961 agcaggccat atcggtggtg cagttggtgg cgcatttcta gcagttatct ttccagttag
    34021 aggagaaaaa cggatgtata acaccagcca gagattagga gcggtagtct tgttcgtagg
    34081 actcgccatt ttgcttttct acaagggaat gggaatgtga cgaagttgaa agaaaatttg
    34141 tgtaatgaaa aaagataagg cattttttga accttatctt tttattttat tccttctcag
    34201 tcaattcttt tccaagttgg atgaggtaat tcttcaaatc atctttgact tgtggatgtt
    34261 tgagggcgta gtcaatagat gttttcataa agccaaactt atccccaacg tcgtaacgag
    34321 ctcctgtaaa ttcacgggca aaaacacgct gtgttttatt aagagtatcg attgcatcag
    34381 taagttggat ttcatttcca gcaccaggag cttggttttc gaggatttgg aaaatttcag
    34441 gcgtgaggag gtagcgtccg ataatagcaa ggtcgctagg agcgtcctct ggagctggtt
    34501 tttcaacaaa ggtttcaaca ctgtaaagac catcttttcc ttcgccttgc ggagcaataa
    34561 ccccgtaagc agatacttcg tcatgaggga ctggcatgac agcgatagta gacgcgtggg
    34621 tacgctcgta gtcatccatg agttgtttgg taagtggaac agccttttcg tctgtgatat
    34681 ccatcaagtc atcaccaagc ataacgacaa aaggttcatt tccgacgaaa gccttggctt
    34741 gcaaaacagc atctccgaga ccgcgtggat gagtttggcg gataaaatgc agccgcatgt
    34801 cagttgtttt atcaactagc ttcaaaagat ctgttttccc tttttctttg aggttatatt
    34861 ccaattcgaa gtttgaatca aagtggtcct caatagaacg ttttgattta ccagtgacaa
    34921 ctagaatatc ttcaatacct gatttgagag cttcttccac gataaactgg atagttggtt
    34981 tgtctacgat tggcaacatt tctttggcaa gggccttggt tgctggtaaa aatcgagttc
    35041 ctagtccagc agcagggatg actgcctttc taacttttga tgtcataaaa atcctttcta
    35101 tagagggtta agaccactca ttttctgctt taaattcatt gttcatgatg tcataaatgg
    35161 catctttgat attggttccg tgataaataa cttggtaaat agcctgtgta atgggcatat
    35221 agactccaag ttcttgggct agttcatagg ctgctcgagt cgttgaaatt ccttcgatta
    35281 ccatgcccat attagcttct atatcagcta gggattctcc tcgtccgaga gcatctccag
    35341 ctctccagtt acgagagtgg atggaagttc ccgttacgat caaatctccc acaccagata
    35401 agccgctata ggtcaatgga ctggccccga gtgctacccc taggcgggtg atttctgcta
    35461 aacctcgagc gatgatggct gccttagcat tatcaccaaa tccaagacca tgtaaagctc
    35521 cagcaccgac agcaataata tttttaagag caccagcagt ttcaaccccg ataacatccg
    35581 tattggtata aagtcggaag tagtgattac taaatagctt ctgaacgtat tgagctgttt
    35641 gtaaatcttt agaagcagca gttattaaag ttaggtcacg cacaatggtc tcttctgcat
    35701 gactaggccc tgaaacaacg acgatatcac tacggagatg ttcaggaatt tcttcttcaa
    35761 gaatggttga taatcgttta tggctatcag gttctaatcc ctttgatgcg tgcatgatga
    35821 taaccttatg gtccaaggtt tgtgcaactt gctgggcaac aagtcgtgtc acttttgttg
    35881 ggacaacaaa caaaatcgca tccacatctt tcaatgtttc tgctaagtcg gtgtaggcaa
    35941 tgatattttc gtctagaacg acatctttaa agtagtgctt attagtatgg tgtgtattaa
    36001 tttcattgat ttgctcggga agatttcccc aaatacgtac ctcgtgtcca ttgtcattta
    36061 agacttgtga aagggcggtt ccccaagaac caggccccaa gacggcgacg gtttgttttt
    36121 ccatgatttc ctccttgata gagttctttc tcttattcta tcatattcta ggggattttg
    36181 cacttgcatt actggggtat ggtggaaaaa tacacaaaaa ccgagacgaa gggataaact
    36241 cttagtcttt agttaaagtg agaagaaatc tgatagatag tttgattcag tatatgctta
    36301 taatagaggt aaacaactca ggaggttctt gtaggttgcg agagtttggc gaaaaaatta
    36361 aaagattacg tttggctaaa aaaatcagtc gttcagaatt ttgtggtgat gagtctgaat
    36421 taagtatccg tcaattaatt agaattgaaa atggagaatc cagaccaata ctaacaaagt
    36481 taaaatatat tgctgaacgt ttggaggttg aagattacaa gttgatgcca agttatatag
    36541 agttggataa ggaataccta gaattgaagt atttcttgat gaggactcct acatacgaag
    36601 atgaaactat cgcccaaaag aaagagagtg tttttgataa gatttttgaa gagtattatg
    36661 ataggctacc tgaggaagaa agatttatca tcccaaatta ttcatatctg gcactaacga
    36721 actacacagt tcaaaaatta ccagaaaagc tagttgaaat actgtccttc tggtgatttt
    36781 gcttaatttc tgatgttcga gacatgattg aggagatttg tcttgatttt ttcctaaaaa
    36841 agggcagact cctcccttgg tttgatgctc gatttttaaa ataaggtgac ttattctgtt
    36901 aggcatgttt tcccctgccc tctagctcta tatggaacag ggagtatcag atttatctgg
    36961 cagattgtat caaataaggc ttgaaactgt tttgaatagg catatagact tgagaatttg
    37021 agaatatgtc gtctagcagt agagacatat tttccggcaa tatgaaggaa gagacgtcga
    37081 aaacgcttga tagtcaaggc ctttacttca tcaccagcta gctgctttaa aaagaggtag
    37141 agattataag ccagacagcc catcatcata cgtacttcat tcttaatcat ggtcgaacta
    37201 tctgtcttat ccccaaagaa tcctgctttc ctttctttga taaagttttc agcattccct
    37261 cgttcacgat agaattgaaa cagctcctca ctatctacac tgcttaaatt ggtcaaatga
    37321 acttttttac aaccataaaa aagagcactt aatcgtactc ttctctttta aggattagtt
    37381 gaattaattc aaatccacta gttctcctgt ttctaggtag actaggcgtt cacaaatgtt
    37441 agcaatgtaa tcagcgaagc gttccagatg ccctatgata taaaggtatt gagttccatt
    37501 gggaattgag gtttcttggt ctttcataag tccaatgatt tcctttgata aggcataata
    37561 atattggtca atctgttcat ctttttgagc aatactaata gcttttgagg cttggtgcaa
    37621 aggaaaggca accaataaat cggctagcat gctgagggat aatttaccca tttggtgtaa
    37681 ctgttcttcg tcaggggcta gttgattttc ttttagttgc aaaacagctt tggcaatgcc
    37741 tgccatatgg tctcccatac gttcaaggtc tgaacaagaa gacatgatgc taatcacaaa
    37801 tcgaaggtca gacacttgtg gctgctgcaa ggccaacaaa cgggcacagg tcaattcgat
    37861 agcgctttga ccttggttga tagcatgatc cttattgata attagctctg ccatctcctt
    37921 gtctttggag gctaaggcca gtaaggcttt tgaagctgtt tcaaggacaa gttgccctag
    37981 tcctaaaaag gattgttcta attcatgcaa ttctaagtca aattgatttc tcataggttt
    38041 ttccttcctt atccgaaccg tcctgaaata tagtcttctg tgcgctgatc ttttggattg
    38101 gtaaacacgt caacggtatc tccaaattcg caaatttctc ctgttaagaa aaaagcagtt
    38161 ttatctgaaa tacgtgaagc ttgttgcatg ttatgggtaa caatgataat cgtataatcc
    38221 ttttttagtt gctgaatgag gtcttcaatt tttaaagtgg agatagggtc taaggctgaa
    38281 gtcggctcat ccattaacag aatatcaggt tctactgcta aagctcgcgc aatgcaaagg
    38341 cgttgctgct gaccgccaga taaggacatg gcactctttt taagatcatc tttgacttct
    38401 tcccaaatgg ctgccccttt taaagatttc tccactaagg catctaattg ttttttgtct
    38461 cgaataccat gtgtccttgg gccataagcc acgttatcat agatagacat ggcaaaggga
    38521 ttaggctgtt gaaaaaccat ccctacacgc ttacgtagct gattaaggtt gaatttgcta
    38581 ctataaatat cttgctcatc taagaggact tggccttcaa tatggcaaga aggaaccaaa
    38641 tcgttcatcc ggttaagggt ttttagaaaa gttgatttgc cacaaccaga tgggcctatc
    38701 aaggcagtaa tctgtctttc tggtaattga atcgaaatat tttttaaggc ttgaaaatcc
    38761 ccgtaaaata agtctaggtg tctgactgaa aatgttccca tactaggaag ctcctttcac
    38821 aagttttcga gataataagc ttgatagagt atttatcatt aaaacagtaa taatcaaaat
    38881 cacaccggta gcataggctt cattgacatg tagcccctca cttgacagca tatacatatg
    38941 cagggctaga gaacgacctg aagacatgag actacttggc gtattggtag aggtacctaa
    39001 tgtatacatg agggcagctg tctcaccaac gatacggcca atagctagta tcactccagc
    39061 taaaatacct ggcatggcaa ctggtagaac aattctaaaa acagtccgta acttacctgc
    39121 cccaagtcca taacttgctt gacgcatgct atcactaaca gataaaaggg cttcttctgt
    39181 tgagcgaata atgactggca acaccatgat gactgaggtt aagattcctg ataacagaga
    39241 gtattgaaaa cctaagaaga ctacaaagaa gagcatgcca aacagaccaa aaacaatgga
    39301 aggaatccca gacaaggtat ctgaggccaa tcgcatgatt ttaacacaaa gggaatcttt
    39361 ttttgtatat tccacaagat aaaaaccagc aaaaatccct atgggcaagg ctaaaagaag
    39421 agcaccaaag accagaataa cggtggaaat aatcgctggc ataagggaaa tgttctcaga
    39481 agtataagtc caagaaaaga gggatagact tagatgaggt aagcctttga tgaggataaa
    39541 accaatgatt aaaaagagag agccaaaggt taaagctgaa aaacaataaa cgagaagttt
    39601 tagcaggtat ttactcataa gatgattttc ctttcaagta ggcaaagtag gcattaatca
    39661 agagaataag gaaaaagaga actgctgagg ttgcaataag ggcttcccta tgctgacctg
    39721 atgcgtaagc catttccaga acaatattgg ttgttaaggt tctggttcct gaaaagagtc
    39781 cacttggaat aatcggctgg ttgcctgcca ccaaaataac tgccatggtt tcacctactg
    39841 cgcgaccgat tcctaaaata actgctgata aaataccaga tctcgcagct ggcaagatga
    39901 cactaaaaat actccgttca tgactagctc ctagagccaa gctaccagaa taatacgttt
    39961 tgggaactgt tcggatagca gattctgaca aactgataat ggttggcaaa atcattattc
    40021 ctaatagtaa cgaagcggtt aggacactca tgccatttcc taaaaagctt ctaatccaag
    40081 gcaccaataa ttgtaggccg aaaaaaccat aaacaataga tggaatggcc gccatcaagt
    40141 tgatagctga ttttaagaag ccatagacgg gctttggaca ataataaacc ataaacaccg
    40201 atgtcaagat gcctgttggc accccaatca caatcgctcc taaggtaatt aataaggaac
    40261 caacgatcat tggtaaaata ccatagcttg ccggaatgtt cgttggcgac caatcactgc
    40321 ctaataaaaa acgggcaaag ccgtagttag ccatgaaagg taagccatta ctaaaaataa
    40381 agaaacagat tagcaaaata gctacaacag ctactgttgc actcatgaaa aaaattgccc
    40441 taaaaactgc ttctttgaag gcttgttttg tcacatcttg tcctttctag tgaagaaagt
    40501 aagggagata cgacacctcc ctacttgcct tctttatctt attgtacgat gaaacgtctg
    40561 catctcttta gagatttatg gagcaaacat tttatttaat cttgtcccag gtggttaatt
    40621 tgccactaaa aacgtctgca agttcagcca tactgacttg gcttgcctta ttgtcattat
    40681 tgaccacaac agcaataccg tctaaagcaa tagcatcatg ggtgagactc ttaccttctt
    40741 caggagttaa ttccctagaa accataccaa tatcagcggt tttctcctta acagcggtaa
    40801 tacctgctga agacccatta gaggtaatat caatcgtaac ttctggattt tcttttttat
    40861 aagcttctgc taatttttcc attaaagaag atactgaagt ggaacctaca acagacaact
    40921 tgcctgataa gtgttggctt gtatattctg tggtttcagt tttagcttca ataaatttat
    40981 tatctgtgac cacttgttga ccttgtttgg agtggataaa gctgataaaa tcttgaccta
    41041 gcttggaaag attagaagac caaacaatgt tgaagggacg ttgaagaggg tattcaccat
    41101 ctaaaactgt gtctcgacta gccttgacac catcaatctc taaagctttg acagatttcg
    41161 ttaaagatcc caaggagatg tagccgatag cattagcatt cccttgaact gctgagagaa
    41221 caccttctgt actattttga atcacagctg ttttggcagt gttgtcaatt tttttatcac
    41281 cgtctttttt gagaatccct gtgatttctg tgaaggcacc ccgtgttcca gagccatttt
    41341 ctcgtgaaat cacctcaatc gttcctgaag ctgactgttt ggaagcagct gactgattgc
    41401 cacaggcaac aagcccaaat cctgataagc caatggctgc aagagtaagc atttttttga
    41461 atttcataat aatcaccttt atctctatgt atttttcttg tgtaggctta ctacatttat
    41521 agtctaacaa gtctttgtaa aggtttatcc ctgattcatg taaagattgt gtaaagaatc
    41581 aaaaaaagcc acttttgaaa aatggctgct cctaaaaata gctttaaaaa ttattagtcc
    41641 tgtgcgaaag attggttagg aagaaaaatc gtgaagcaac tgcctctgcc aagctgactc
    41701 gtcaccgtga cttggccacc taataattga ctgagttctt tgacaatggc aaggccaaga
    41761 ccagtgccac cagtttgtct gcttcgacct ttattaactc ggtaaaaacg ttcaaaaata
    41821 cgatcctgct ctaattgact aataccaatc cctgtatctg atacagaaat cttaatgcct
    41881 tcgttcacct tttgggtctt gacctcaatt tttccccctt gttcagtgta acggatggca
    41941 ttggataaaa gattgagtaa gatttgggaa agtaattgac tatctgatac gagggtgaca
    42001 tcatctggca cctgcacctt tagctgtaaa tccttcttct tgagctgagg ttgcaagctt
    42061 tgagtcaaat cctgtacaaa ttctgccaaa gaaagggtcg tccattgtat aggcatttgt
    42121 tgagccttag ataaggtaag aagatgctca acaatatgct caagacgcaa gctttctttg
    42181 taaataatgt ctagaaagtc atccttgagc gcttcttctt cagctgacat ccccttaatg
    42241 gtttcagcaa agcccttaat cgaagtaact ggtgtcctca attcatggga ggcatttgag
    42301 acaaaggcta aatttaactt ttcataagtt ctaatcgttg ttaaatcata tagcaagacg
    42361 agcacagctt ccacagattg ggtggggcta aaaacgggaa ctgctgtcac ttctaaaatc
    42421 aagtcaccct catgaaaccc acttacttct tgttttaacc ttgttttttg atcaaaggct
    42481 tggtgaacta aatttcgaat atccatccgt ttgaggtcat caagtgaact tatgtcgccg
    42541 tccacatcgg gaaaataatg aggcagagag cgactggata ataacatctg accttgagcg
    42601 gaaactaaaa acgtccccat ggttaggtgc gacagaagaa cctccattgt ttcggctagg
    42661 tccttgtatt gctgatcctg ttgggagact ttggttttta gggcagacac atactgagcc
    42721 aaagacttta agtcttcttg ccctttttct aaaaagtatt cactactggt caagagaggt
    42781 tggtgcaagg tctcaaaagc aacttcccat ttccaaaggc aaaagagcca gtagccacct
    42841 tgtcccaaag aaagggctag aagaaagaga ccgatgcctt tactgatcca agttaatgcc
    42901 atccctgcaa tcagaatgag gctaacactt agattgacta gccaaaattg aaggtagcgt
    42961 ttcatctata actccttgaa cttataacca taaccccgaa tggttcgaat aaattgaggg
    43021 gctttaggat tgtcttcaat tttttccctc aacttaccaa tatgaacgtc caccaaacgt
    43081 gtttcctgcc caaagtcata cccccagata cgttccaaaa gacgctctct agtcagtgtc
    43141 atgttgggat gtttcataag atagagcaag agttcaaatt cttttggggt caaactcagt
    43201 aacttattcg ccttgtagac ttcatgacgc tcagggtata ctttcaaggt cccaaatagc
    43261 caagaatcgt cagcgatatt atctgaatca tctccttctt gttctccttt agttcgcctg
    43321 aggacagcct tgacacgcgc cagcaattct ctagggctaa aaggtttggt caggtagtca
    43381 tcagccccta attccaaggc caaaacctta tcaaattcat cacttttcgc agaaaccatc
    43441 ataattggag ttttgacgcc tttggctctc agccgcttac aaacttccat gccatctaat
    43501 tgtggtaaca tgatatcaag caagataaaa tcaaagggtt ctgtttctgc caaagctaag
    43561 gccttccgtc catttgttac caattgagta gaaaagcctt ccttacttaa atggtagtca
    43621 agcaatttca gaatgtgttc ttcatcatcc actaataaga cttgttttgt catctattat
    43681 ctcctattgg taacattata acacaattat cagaaatcct aacattgcta aatcagatta
    43741 aatttgctta tcaagactag tatctggtca aacgctcaat catctccttg tgctctggat
    43801 aggtcgccag tagatctacc ctttcaaata attcaaaatc ctcaaattca aaaccaggag
    43861 caacaagaca agaaaccaga gcatcatcct tatcaactgt tgatccccaa atagtgccct
    43921 taggaacaca gtagtgaagt tgttgccctt tggatatgtc caggcctaaa gtgactgctt
    43981 cgtagtgacc atctgctgta atcatgtgaa cagtaagtgg ggattctgca tgaaaatacc
    44041 agatttcatc tgctgtcaat cggtgaaaat gtgaaggatt cgtttcttct taataagaaa
    44101 taaatactgg tataaagcgc ccttccctta ccagcaaggt ttatagtgtc tgaagctttt
    44161 tttgtttgtc taaaatagcc accttcaaca tggggagcta actctagagt tcttatcaag
    44221 tcttctttat ccgtcggagc caatgggttg aagtaactct tgttcaaagg tggtgttacg
    44281 atttcaagaa ctcctctcag ctctgaggac acgataatga ttgatgcgac ggaagtaaaa
    44341 atcaatcgcc ctaaaaaaac aattagcgaa taattctggt aaaaagaaat ttcacgctat
    44401 gaaggctcaa gcgattgtca caagtcaagg gagaattgtt tctttggata tcgctgtgaa
    44461 ctattgtcat gatatgaagt tgttcaaaat gagtcgcaga aatatcggac aagctggtaa
    44521 aatcttggct gacagtggtt atcaagggcc catgaagata tatcctcaag cacaaactcc
    44581 acgtaaatcc agcaaactca agccgctaac agttgaagat aaagcctgta accatgcgct
    44641 atctaaggag agaagcaagg ttgagaatat ttttgccaaa gtaaaaacgt ttaaaatgtt
    44701 ttcaacaacc tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgg
    44761 cattatcaat catgaactag gattctagtt ttgcaggaag tctattattt ggttaggtga
    44821 attagtgaag cgtttaggca agtgtctctg gttacgacgt catggcctct aaatcgatta
    44881 tatttagggg tcatgactag tgaagcagtt agctagttcg catataagcg gctagcgtct
    44941 aacaattagg aactttagtt ccaataactt taagattacg acgttttagg acataaatcg
    45001 atcatattta tgtcctaaaa ctagtgaagc gcctagccaa agtccgaata ggatttggcg
    45061 ttagttactt agattgcttt gcaatcaagt aactttggcg atttacatct tctctggcgc
    45121 ttctactcca agcaagcgaa gggcttcttt gagaacgact gcggttgcgt agctgagggc
    45181 tagacggctg tcgcgttctg ggctttcatc caagatacgt gtatgtgcat agtatttgtt
    45241 aaaggattga gccaggctaa ttgcaaattt agcaatgata gaaggttcaa agttatctgc
    45301 cgcacggttg ataatacgtg ggaagtcttg aatgagttta atgatttccc agctttcagt
    45361 atcattcaag ctatagttgc cagctgtttc tggtttgaaa tcggctttgc gtaagataga
    45421 ttggatacga gcgtaggcat attgaacgta aggtccagtt tcaccctcga aggataccat
    45481 agcttctagg tcgaagtcgt atccatttgt acggtcggtt ttgaggtcat agaatttaat
    45541 ggctccaacc ccaacagcat gtgctacttg gtctttgttt tctagttcag gatttttagc
    45601 ctcgatttgg accttggcac ggctaacagc ctctgcaata gtaggctcta gcaagatgac
    45661 attcccttta cgagtagaga gcttcttccc ttcttttgta accagaccaa aaggaacgtg
    45721 ggtaatgtcg tcactccaat cgtagcccat ctcttgcaag acagctttga gctgtttaaa
    45781 gtgggcagat tgttcttgac caacgacgta gatagattta gcaaattggt attcattttt
    45841 acggtagagg gctgcagcca agtcacgtgt gatatagaga gttgcaccat cagacttctt
    45901 gatgagggct ggatgttcaa ttccgtattt ctcaagattc acaacttggg caccttctga
    45961 ttcaagaagt agtccttttt cagaaagaat gtctacaact gcatccatct tatcattgta
    46021 gaaggcttct ccgttatagc tgtcaaattc aaccttcaat tcattgtaaa ggcggttaaa
    46081 ttccactaaa ctttcatcgc ggaaccattg ccaaagagcg agagcttcct catctccatt
    46141 ttcaagttta cggaaccatt cgcgcgcttc ttcatccaag ctagggtcat tttcagcttc
    46201 agcgttgatg cggacataga gtttaaggag ttcatcgatt ggatgagctt ttacagcttc
    46261 ttcgtcgccc cattttttgt aggcaacaat caacatccca aattgtttac cccagtctcc
    46321 caaatggttg accttgaccg tttgataacc gattttttgg aaaatatgtg acaagctatc
    46381 tccgataaca gttgaacgca ggtggccaat agaaaatggt ttagcgatat tcggactaga
    46441 catgtcgata acaacatttt cttgtttacc aatattttgg tcagcatagt gttctttttc
    46501 agtggtaaca gcttgcaata cttgagcaga aatggcagat ttatcaagga aaaagttaac
    46561 gtaaggtcct gttgcgacaa ctttttcaaa ggcttggctg ttcatttttt cagccagttc
    46621 agccgcaatc atttgtggtg ctttacgttc gacttttgca agagaaaaag cagggaaagc
    46681 aatgtctccc atttctgagt ttttaggggt ttccagtaac tttaaaatag cctcttggtc
    46741 caggctatca atgatgctag ataatttgct agcaatcaat tcttttgtat tcattaagag
    46801 ctcctttttg gacttttcta ctattttatc acaattttaa agaaagaaga aaaaattttt
    46861 gaaatctcct gtttttttgg tataatatgg ttataaatat agttataaat atgcacgcaa
    46921 gaggatttta tgagaaaaag agatcgtcat cagttaataa aaaaaatgat tactgaggag
    46981 aaattaagta cacaaaaaga aattcaagat cggttggagg cgcacaatgt ttgtgtgacg
    47041 cagacaacct tgtctcgtga tttgcgcgaa atcggcttga ccaaggtcaa gaaaaatgat
    47101 atggtgtatt atgtactagt aaatgagaca gaaaagattg atttggtgga atttttgtct
    47161 catcatttag aaggtgttgc aagagcagag tttaccttgg tgcttcatac caaattggga
    47221 gaagcctctg ttttggcaaa tattgtagat gtaaacaagg atgaatggat tttaggaaca
    47281 gttgctggtg ccaatacctt attggttatt tgtcgagatc agcacgttgc caaactcatg
    47341 gaagatcgtt tgctagattt gatgaaagat aagtaaggtc ttgggagttg ctctcaagac
    47401 ttatttttga aaaggagaga cagaaaatgg cgatagaaaa gctatcaccc ggcatgcaac
    47461 agtatgtgga tattaaaaag caatatccag atgctttttt gctctttcgg atgggtgatt
    47521 tttatgaatt attttatgag gatgcggtca atgctgcgca gattctggaa atttccttaa
    47581 cgagtcgcaa caagaatgcc gacaatccga tccctatggc gggtgttccc tatcattctg
    47641 cccaacagta tatcgatgtc ttgattgagc agggttataa ggtggctatc gcagagcaga
    47701 tggaagatcc taaacaagca gttggggttg ttaaacgaga ggttgttcag gtcattacgc
    47761 cagggacagt ggtcgatagc agtaagccgg acagtcagaa taattttttg gtttccatag
    47821 accgcgaagg caatcaattt ggcctagctt atatggattt ggtgacgggt gacttttatg
    47881 tgacaggtct tttggatttc acgctggttt gtggggaaat ccgtaacctc aaggctcgag
    47941 aagtggtgtt gggttatgac ttgtctgagg aagaagaaca aatcctcagc cgccagatga
    48001 atctggtact ctcttatgaa aaagaaagct ttgaagacct tcatttattg gatttgcgat
    48061 tggcaacggt ggagcaaacg gcatctagta agctgctcca gtatgttcat cggactcaga
    48121 tgagggaatt gaaccacctc aaacctgtta tccgctacga aattaaggat ttcttgcaga
    48181 tggattatgc gaccaaggct agtctggatt tggttgagaa tgctcgctca ggtaagaaac
    48241 aaggcagtct tttctggctt ttggatgaaa ccaaaacggc tatggggatg cgtctcttgc
    48301 gttcttggat tcatcgcccc ttgattgata aggaacgaat cgtccaacgt caagaagtag
    48361 tgcaggtctt tctcgaccat ttctttgagc gtagtgactt gacagacagt ctcaagggtg
    48421 tttatgacat tgagcgcttg gctagtcgtg tttcttttgg taaaaccaat ccaaaggatc
    48481 tcttgcagtt ggcgactacc ttgtctagtg tgccacggat tcgtgcgatt ttagaaggga
    48541 tggagcaacc tactctagcc tatctcatcg cacaactgga tgcaatccct gagttggaga
    48601 gtttgattag cgcagcgatt gctcctgaag ctcctcatgt gattacagat gggggaatta
    48661 tccggactgg atttgatgag actttagaca agtatcgttg cgttctcaga gaagggacta
    48721 gctggattgc tgagattgag gctaaggagc gagaaaactc tggtatcagc acgctcaaga
    48781 ttgactacaa taaaaaggat ggctactatt ttcatgtgac caattcgcaa ctgggaaatg
    48841 tgccagccca ctttttccgc aaggcgacgc tgaaaaactc agaacgcttt ggaaccgaag
    48901 aattagcccg tatcgaggga gatatgcttg aggcgcgtga gaagtcagcc aacctcgaat
    48961 acgaaatatt tatgcgcatt cgtgaagagg tcggcaagta catccagcgt ttacaagctc
    49021 tagcccaagg aattgcgacg gttgatgtct tacagagtct ggcggttgtg gctgaaaccc
    49081 agcatttgat tcgacctgag tttggtgacg attcacaaat tgatatccgg aaagggcgcc
    49141 atgctgtcgt tgaaaaggtt atgggggctc agacctatat tccaaatacg attcagatgg
    49201 cagaagatac cagtattcaa ctggttacag ggccaaacat gagtgggaag tctacctata
    49261 tgcgtcagtt agccatgacg gcggttatgg cccagctggg ttcctatgtt cctgctgaaa
    49321 gcgcccattt accgattttt gatgcgattt ttacccgtat cggagcagca gatgacttgg
    49381 tttcgggtca gtcaaccttt atggtggaga tgatggaggc caataatgcc atttcgcatg
    49441 cgaccaagaa ctctctcatt ctctttgatg aattgggacg tggaactgca acttatgacg
    49501 ggatggctct tgctcagtcc atcatcgaat atatccatga gcacatcgga gctaagaccc
    49561 tctttgcgac ccactaccat gagttgacta gtctggagtc tagtttacaa cacttggtca
    49621 atgtccacgt ggcaactttg gagcaggatg ggcaggtcac cttccttcac aagattgaac
    49681 cgggaccagc tgataaatcc tacggtatcc atgttgccaa gattgctggc ttgccagcag
    49741 accttttagc aagggcggat aagattttga ctcagctaga gaatcaagga acagagagtc
    49801 ctcctcccat gagacaaact agtgctgtca ctgaacagat ttcactcttt gatagggcag
    49861 aagagcatcc tatcctagca gaattagcta aactggatgt gtataatatg acacctatgc
    49921 aggttatgaa tgtcttagta gagttaaaac agaaactata aaaccaagac tcactagtta
    49981 atctagctgt atcaaggaga cttctttgac aattctccac ttttttgcta gaataacatc
    50041 acacaaacag aatgaaaagg agctgacgca ttgtcgctcc cttttgtcta ttttttaagg
    50101 agaaagtatg ctgattcaga aaataaaaac ctacaagtgg caggccctgg cttcgctcct
    50161 gatgacaggc ttgatggttg ctagttcact tctgcaaccg cgttatctgc aggaagtctt
    50221 aggcgccctc cttgctggga aatatgaagc tatttatagt atcggggctt ggttgattgg
    50281 tgtggccgta gtcggtctag ttgctggtgg actcaatgtt gtcctcgcag cctatattgc
    50341 ccaaggagtt tcatccgacc ttcgggagga tgccttccgt aaaattcaaa ccttttctta
    50401 tgctgatatt gaacaattta atgcgggaaa tctagtcgtt cgaatgacaa atgatatcaa
    50461 ccagattcag aacgttgtca tgatgacctt ccagattctt ttcagacttc ccctcttgtt
    50521 catcggttcg tttatcctag cggttcaaac cttaccttct ctgtggtggg tgattgttct
    50581 catggtagtc ttgatttttg gtttgactgc tgtcatgatg ggaatgatgg ggcctcgttt
    50641 tgccaagttt caaacccttc ttgagcgcat caatgccatt gccaaggaaa atttacgtgg
    50701 cgttcgtgtg gtcaagtcct ttgtccaaga aaaagagcaa tttgctaagt ttacagaggt
    50761 ctcagacgag cttcttggtc aaaaccttta cattggttat gccttttcag tagtggaacc
    50821 ctttatgatg ttggttggtt acggggcggt cttcctctct atttggctgg tcgcgggaat
    50881 ggttcagtcg gatccgtctg ttgttggttc catcgcttct tttgttaatt acctaagcca
    50941 gattatcttt accattgtta tggttggatt tttgggaaat tctgtcagcc gtgccatgat
    51001 ttccatgcgt cgtattcgag aaattcttga cgcagagcca gctatgacct tcaaggatat
    51061 cccagatgaa gagttggttg gaagccttag ctttgaaaat gtgaccttta cctatccaat
    51121 ggacaaggaa ccgatgctga aagatgtgag ctttactatt gaacctggtc aaatggttgg
    51181 tgtagttgga gcgactggtg caggaaagtc aaccttggct caattgattc cacgtctctt
    51241 tgatccacag gaaggggcta tcaaaatcgg aggtaaggat attcgagaag tgagtgaagg
    51301 aaccctgcgt aaaacagttt ccatcgttct ccaacgtgcc attcttttta gtggaacgat
    51361 tgcagataac ttgagacagg ggaagggaaa tgctactcta tttgaaatgg agcgcgcagc
    51421 caatattgcc caggctagtg aattcattca tcgtatggag aaaacctttg aaagtccagt
    51481 tgaagaacgg ggaaccaatt tctctggtgg acaaaaacaa aggatgtcga ttgcgcgtgg
    51541 gattgtcagc aatccacgta ttctgatttt tgatgattcg acctcagcct tggatgccaa
    51601 atcagagcgc ttggtgcaag aagctttgaa taaggacttg aaggggacga caaccattat
    51661 tattgctcaa aaaattagct cggttgtcca tgcagacaag atcttggttc taaatcaagg
    51721 acgattgatt ggtcaaggca cgcatgcaga cttggttgcc aacaatgccg tttaccgtga
    51781 aatctatgaa acacagaaat gaaagacaaa ctataagaaa agtcaatagt tttatctaaa
    51841 ctatttctta tttcaatttg atgatttggc gatgatttta gagcacggca aaaagctatt
    51901 gaaaaagtcc attttttcaa aggtaatcct gtgttaattt cagaaattac atcacttttt
    51961 gttcgtcaaa tggcagctct tttttaggat ataaaacagg gttcggataa gtttttttgc
    52021 aaggtggatg atggctacat tgtaatgttt tccttgttct aacttagtct taagataggc
    52081 cttaaaagca ggtgaaaagc gagggcatgc tttggcagct tgtatgagta cctaccgcag
    52141 atgaggggaa ccccgtttga ccattcttcc tgctaaatca atctgacctg actgataaat
    52201 agaagaatcc agtccagcga aagcttgtaa ttgagcagga ttatcaaagg catgaatatt
    52261 tcgaatctcg gctaaaatga ccgcccctaa acgattctca atcccagtaa ccgtcgtgat
    52321 gaccgagttg aactcagcca tcaagtcatt gacacatttt ttcgccttgt caatgagcct
    52381 cttgtaatgt ttgatgtttt cattacaaga gataaaacgt ttatgcgtta tcaaactcat
    52441 taccaattga aacaaaaagc tgtggttaga tcctttcgga aattgtcaag cgattggagg
    52501 aaatgaacta atccacagcg gcttattcca agtataccac ttgggctttg gcagtagcta
    52561 actgcgctaa atataatata aggaggagta aaatgaagac agttcaattt ttttggcatt
    52621 attttaaggt ctacaagttc tcatttgtag ttgtcatcct gatgattgtt ctggcgactt
    52681 ttgcccaagc cctctttcca gtcttttctg gacaagcggt gacgcagcta gccaatttag
    52741 ttcaagctta tcaaaatggc aatccagaac ttgtatggca aagcctatca ggaatcatgg
    52801 tcaatcttgg cctgctggtt ttggttctat ttatctctag tgtaatatac atgtgtctca
    52861 tgacgcgcgt gattgcagaa tcgaccaacg agatgcgcaa aggcctcttt ggtaagcttg
    52921 ctcagttgac ggtttctttc tttgaccgtc gacaagatgg cgatatcctg tctcatttta
    52981 ccagtgattt ggataatatc ctccaagcct ttaacgaaag cttgattcag gtcatgagca
    53041 atattgtttt atacattggt ctgattcttg tcatgttttc gagaaatgtg acgctggctc
    53101 tcatcaccat tgccagcacc ccattggctt tccttatgct gattttcatc gtgaaaatgg
    53161 cacgtaaata caccaacctc cagcagaaag aggtagggaa gctcaacgcc tatatggatg
    53221 agagcatctc aggccaaaaa gccgtgattg tgcaaggaat tcaagaggat atgatggcag
    53281 gatttcttga acaaaatgag cgcgtgcgca aggcaacctt taaaggaaga atgttctcag
    53341 gaattctttt ccctgtcatg aatgggatga gcctgattaa tacagccatc gtcatctttg
    53401 ctggttcggc tgtacttttg aatgataagt ctattgaaac aagtacagcc ctaggtttga
    53461 ttgttatgtt tgcacaattt tcacagcagt actaccagcc tattatccaa gttgcagcga
    53521 gttggggaag ccttcagttg gcctttactg gagctgaacg aattcaggaa atgtttgatg
    53581 cagaggagga aatccgacct gaaaaggctc caaccttcac taagttgcaa gaaagtgttg
    53641 aaatcagtca tatcgatttt tcatacttgc ctgataaacc tattttgaaa gatgtcagca
    53701 tttctgcccc taaaggccag atgacagcag ttgttgggcc tacaggttca ggaaaaacga
    53761 ctattatgaa cctcatcaat cgcttttatg atgttgatgc tggtggtatt tattttgatg
    53821 gtaaagacat tcgtggctat gacttagata gtcttagaag caaggtggga attgtattgc
    53881 aagattcggt cttgtttagc ggaacgattc gagacaatat ccgatttggt gtgccagatg
    53941 ctaatcagga aatggttgag gtagcagcaa aagcaaccca cattcacgac tatatcgaaa
    54001 gtttgcctga taagtacgat actcttattg atgatgacca gagcatcttt tcaacagggc
    54061 agaagcaatt gatttcaatc gctcgaaccc tgatgacaga tccagaagtt ctcattctcg
    54121 atgaagcaac ttcaaacgta gatacggtga cggaaagcaa gattcagcat gccatggagg
    54181 tggttgtagc aggtagaact agtttcgtca ttgcccaccg cttgaaaacc attctcaatg
    54241 cagatcagat tattgtcctt aaagatggag aagtcattga acgtggtaac caccatgaac
    54301 ttttgaagct aggtggcttt tattcagaac tctatcacaa tcaatttgtt ttcgaataag
    54361 aaagaagttg tcctatgtgg gcagcttttt cttgtccata aaaaatgttt atcacagcct
    54421 taaaaaaaac atattagacg aaagtcattt tgagtgatat gataggacta tcgttagtat
    54481 tcgaaaggag aggcatcatg gctagaacgg ttgtaggagt tgctgcaaat ctatgtcccg
    54541 tagacgcaga aggcaaaatc attcattcat ctgtatcttg tagattcgca gagatcattc
    54601 gtcaagtcgg tggtctccct ttagtcattc ctgttggtga tgagtcagtt gtacgtgatt
    54661 atgtggaaat gattgacaaa ctcattttga caggaggcca aaatgttcat cctcagtttt
    54721 atggagagaa aaagaccgtc gaaagcgatg attacaatct ggtccgtgac gaatttgaat
    54781 tggcactctt gaaggaagcg cttcgtcaga ataaaccaat tatggcaatc tgtcgcggtg
    54841 tccaacttgt caatgttgcc tttggtggaa ccctcaatca agaaatcgaa ggtcactggc
    54901 aaggactacc tttcgggaca tctcactcta ttgagacagt agaaggaagc gtggtggcta
    54961 agctatttgg gaaagaaagt caggtcaact cagtccatcg tcaaagcatt aaagatttgg
    55021 cacctaattt ccgtgtaact gctattgatt caagagacca aactattgaa gcgattgagt
    55081 ctatcgacga gcaccgcatt atcggtttac agtggcatcc agagtttctg gttaatgaag
    55141 aagatggcaa tttagaatta tttgagtatt tattgaatga actgtaacga ttggaacatc
    55201 tggtcgttct ttcttttatt ttttcaaaat ttttagaatg tggcatttta cgcaaacgtt
    55261 tgaattctga taaaaattgg agaaattcga caaaaaaact tgaaaaaaac gaaggtaagc
    55321 gttatgatag aaaagaagaa atattggagg aagaacatgt cacatattaa atttgattat
    55381 tcaaaagttt tagacaaatt tgttgcacca catgaagtgg aatacatgca atcacaagta
    55441 acagcagcag atgaattgat ccgtaaagga actggtgctg gtagcgactt cttgggatgg
    55501 ttggaccttc ctgaaaaata cgaccgcgaa gaatttgacc gcatcttgaa agctgctgag
    55561 caaatcaagt cagacagcga tgttttggtt gtgatcggta ttggtggatc ttaccttggt
    55621 gcaaaagcag caatcgactt cttgaatcac cattttgcta acttgcaaac aaaagaagaa
    55681 cgcaaagctc cacaaatcct ttacgcagga aactcaatct catctactta ccttgctgac
    55741 ttggtagagt atgttgcaga caaagacttc tcagtaaacg taatttctaa atcaggtaca
    55801 acaactgaac cagcgattgc tttccgtgtc tttaaagaac tcttggttaa gaaatacggt
    55861 caagaagaag ctaacaaacg tatctatgca acaactgacc gccaaaaggg tgctgttaag
    55921 gttgaagcag acgctaacgg ttggggaaca tttgttgttc cagatgatat cggtggacgc
    55981 ttctcagtat tgacagccgt tggtttgctt ccaatcgcag catcaggagc tgacatcaaa
    56041 gctcttatgg aaggtgcgaa tgcagctcgc aaagactaca cttcagacaa aatctctgaa
    56101 aacgaagctt accaatacgc agtcgttcgt aacatccttt atcgtaaagg ctatgcaact
    56161 gagatcttgg taaactatga gccatcactt caatacttct cagaatggtg gaaacaattg
    56221 gctggtgaat cagaaggaaa agaccaaaaa ggtatctacc caacttcagc caacttctca
    56281 actgacttgc actcacttgg tcaatttatc caagaaggaa ctcgtatcat gtttgaaaca
    56341 gttgtccgtg ttgacaaacc tcgtaaaaac gtgcttattc ctactttgga agaagacctt
    56401 gacggacttg gttaccttca aggaaaagac gttgactttg taaacaaaaa agcaactgac
    56461 ggtgttcttc ttgcccacac agatggtgat gtaccaaaca tgtatgtgac tcttccagag
    56521 caagacgctt tcactcttgg ttacactatc tacttcttcg aattggcaat tgccctttca
    56581 ggttacttga atgctatcaa cccatttgac caaccaggtg ttgaagctta taaacgtaac
    56641 atgtttgccc ttcttggaaa accaggattt gaagaattga gcaaagaact taacgcacgt
    56701 ctataataga agaaaagagt ggtttgccca ctctttttac tctctttatc catagaaatt
    56761 ggactcagcc aagacttgtg atataatata gaaagcaaaa aggcagacgc ctagataata
    56821 ggagaaacta tgtcaaaaga tatccgcgta cgttacgcac caagtccaac aggactacta
    56881 cacatcggaa atgcccgtac agcattgttt aactacttgt atgcgcgcca tcatggtgga
    56941 acatttctca tccgtatcga agatactgac cgtaaacgcc atgtcgagga tggtgaacgt
    57001 tcacaacttg aaaaccttcg ctggttaggc atggattggg atgaaagtcc agaatcacat
    57061 gagaattatc gccagtctga gcgtttggac ttgtatcaaa aatacattga ccaactatta
    57121 gctgaaggaa aagcctataa atcttacgtt acagaagaag agttggcagc tgaacgtgaa
    57181 cgtcaagaag tagctggcga aacaccacgc tacatcaatg aataccttgg tatgagtgaa
    57241 gaagaaaaag cggcttatat cgcagaacgt gaagcagctg gtatcatacc aacagttcgt
    57301 ttggctgtca atgagtcagg tatctacaag tggcatgata tggtcaaagg tgatatcgaa
    57361 tttgaaggtg gcaatatcgg cggtgactgg gttatccaaa agaaagacgg ttacccaact
    57421 tacaactttg ccgttgttat cgatgaccac gatatgcaaa tctctcatgt tatccgtgga
    57481 gatgaccata ttgctaatac accaaaacag cttatggtct atgaagctct tggttgggaa
    57541 gctccagagt ttggtcacat gaccttgatt atcaactctg agactggtaa gaagttatct
    57601 aaacgtgata ctaatacact tcaatttatc gaagattacc gaaagaaagg ttaccttcca
    57661 gaagcagtct ttaactttat tgctcttctt ggttggaacc caggtggtga agatgagatt
    57721 ttctctcgtg aagaactcat taaacttttt gatgaaaacc gcctcagcaa gtcaccagca
    57781 gcctttgatc agaaaaaatt agactggatg agcaatgatt atatcaagaa tgcagacctt
    57841 gaaaccatct ttgaaatggc aaaaccattc ttagaggaag caggccgttt gactgacaag
    57901 gctgaaaaat tagttgagct ctataaacca caaatgaaat cagtagatga gattatccca
    57961 ttgacagatc ttttcttctc agatttccca gaattgacag aagcagagcg cgaagtcatg
    58021 acgggtgaaa cagttccaac agttcttgaa gcattcaaag caaaacttga agcgatgaca
    58081 gatgatgaat ttgtgacaga aaatatcttc ccacaaatta aagcagtcca aaaagaaaca
    58141 ggtattaaag ggaaaaatct tttcatgcct attcgtatcg cagtttcagg cgaaatgcat
    58201 gggccagaat taccagatac aattttcttg cttggacgtg aaaaatcaat tcagcatatc
    58261 gaaaacattc taaaagaaat ctctaaataa agaggataca ataatggaca tctgggaaaa
    58321 gatgtacgaa gaagcacaga aactatacaa tccacatgaa gtatcagact ttgtttatgc
    58381 caatcatgtt gtagctgcag tagaagcagg agatggacaa atatttacag gattctgtat
    58441 ggagggaacc tgtggtgttt tccatctctg cgcagaacgg gcgaccctct tcaatatgta
    58501 ccaattttca ggacaaacta aggttaagaa agtattagcc tttcgagaca aaccacctta
    58561 tggtggaagt tcagccatgc cttgcggtgc ttgtagagaa ttccttttag agcttaatgc
    58621 tgaaaataaa gatgcagaat tcatgatgga ctataatata agaaaaacag ttaaagtcgc
    58681 agaactaatc ccttattggt ggggagaaga acgtgcttct aagtttaatg agtgatagaa
    58741 gagtcagtat aattctggct ctttttacta taagttgaaa aaataaaaaa aattagaaaa
    58801 agtagttgac aaa
//
LOCUS       DAVMJI010000010        57034 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.010, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000010 DAVMJI010000000
VERSION     DAVMJI010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57034
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.010"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(127..987)
                     /locus_tag="VYR58_000727"
     CDS             complement(127..987)
                     /locus_tag="VYR58_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEV3621924.1"
                     /translation="MKYGKIFKKFRESRGLSLKDVAKSGLSSSHLSRFEHDEADLTIS
                     KFLLALDAIHMPIEEFVYAVRDFRRDDFNELLEKIRYLVSKCDIDGMKKLLISQIEKK
                     DKKEPFDSFNTILLKIRLQDLLEEILVTDQEIGIISDYLFSVEYWGYYELLLFMNTID
                     VLNHKTMMVLAKEMCHRSEFYREIPNNRRLLATMLLNAYITCIERNELMDALYFEKQL
                     KYCNFSETEMYEKLVLHYTKNLYDLKKNNNRYAVLEMRKCIATMKLVDSNQTALKFEN
                     HLQKVLGDLA"
     gene            1556..1720
                     /locus_tag="VYR58_000728"
     CDS             1556..1720
                     /locus_tag="VYR58_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621925.1"
                     /translation="MATISLTRDIKLTNEDALKILNHKPSKKLQAVLKSIESQDATAP
                     TKNKLISKYL"
     gene            1722..2330
                     /locus_tag="VYR58_000729"
     CDS             1722..2330
                     /locus_tag="VYR58_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621926.1"
                     /translation="MTIQVTPLKQYLENIQVLAPDKTEKQVQELFKTIILENVDFNGN
                     EEMLTYLSDKAPNFEKQHRSRNFIVEETETNNIIGFFSLSLKVVDISDLEKSLKKKLV
                     LKGKSPKNIDYLPVLLIGQFGKNTNLNKLSGQELFEIVIQKIEEFRAIVGTQMVFLDS
                     INHPKVIQFYEQFGFVAYSQLIKDDHQVTYQPMALNMSLYKK"
     gene            complement(2365..5178)
                     /locus_tag="VYR58_000730"
     CDS             complement(2365..5178)
                     /locus_tag="VYR58_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV3621927.1"
                     /translation="MKDKRKIIRARKAFRRSLKDEKKFLKKGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKESRKERKTNQKFLYGQETKAKSNFFFQGKSLEELKAKKE
                     VKDAKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     YRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPV
                     HLFSSETYKDYLSTLWHDLNDGEDLKSMQDLYETPKYKLSKDDQEEMKELKEEGVYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQAIVAPMDGVVSL
                     DGDNVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDIIGETPDDTGLKVSYQKFKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATASSWDDETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VSTASSLGGETGSIPRAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTVK"
     gene            complement(5190..7547)
                     /locus_tag="VYR58_000731"
     CDS             complement(5190..7547)
                     /locus_tag="VYR58_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV3621928.1"
                     /translation="MKRKSNTLKKQKTSMTNKKEEVKGKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDTYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEDRVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGIFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSDENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            complement(7498..7857)
                     /locus_tag="VYR58_000732"
     CDS             complement(7498..7857)
                     /locus_tag="VYR58_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEV3621929.1"
                     /translation="MNTCVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            complement(7911..8765)
                     /locus_tag="VYR58_000733"
     CDS             complement(7911..8765)
                     /locus_tag="VYR58_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HEV3621930.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTLSGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            complement(8782..9024)
                     /locus_tag="VYR58_000734"
     CDS             complement(8782..9024)
                     /locus_tag="VYR58_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621931.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            complement(9045..10922)
                     /locus_tag="VYR58_000735"
     CDS             complement(9045..10922)
                     /locus_tag="VYR58_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEV3621932.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQESDERWWNYQINPLNQRQENYLDDLRIRDLTFESSL
                     K"
     gene            complement(10922..11410)
                     /locus_tag="VYR58_000736"
     CDS             complement(10922..11410)
                     /locus_tag="VYR58_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621933.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYAIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     AKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            complement(11400..11699)
                     /locus_tag="VYR58_000737"
     CDS             complement(11400..11699)
                     /locus_tag="VYR58_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621934.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIVDGKAVEVTLREPYSRDLLKVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL"
     gene            12372..12686
                     /locus_tag="VYR58_000738"
     CDS             12372..12686
                     /locus_tag="VYR58_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV3621935.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            12702..13088
                     /locus_tag="VYR58_000739"
     CDS             12702..13088
                     /locus_tag="VYR58_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV3621936.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            13117..14502
                     /locus_tag="VYR58_000740"
     CDS             13117..14502
                     /locus_tag="VYR58_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV3621937.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            14505..14657
                     /locus_tag="VYR58_000741"
     CDS             14505..14657
                     /locus_tag="VYR58_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV3621938.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            14680..16098
                     /locus_tag="VYR58_000742"
     CDS             14680..16098
                     /locus_tag="VYR58_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEV3621939.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKKGYLSTIPVDRYPKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMEI
                     RLRSKLKSVLIVHYLKILYNRN"
     gene            16147..16230
                     /locus_tag="VYR58_000743"
     CDS             16147..16230
                     /locus_tag="VYR58_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEV3621940.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            16355..17092
                     /gene="erm(B)"
                     /locus_tag="VYR58_000744"
     CDS             16355..17092
                     /gene="erm(B)"
                     /locus_tag="VYR58_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEV3621941.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(17349..18596)
                     /locus_tag="VYR58_000745"
     CDS             complement(17349..18596)
                     /locus_tag="VYR58_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV3621942.1"
                     /translation="MSHNDSILNILGIKDKNIKIISVEEAEHNNDSVKEYITLITATL
                     SYPINRCRNCGFPTVNKDGFRKTHVRLASLNGRRYELELRKQRYKCKSCHTTFGAITN
                     LTKENQTLSSDLKNQIMLLARKGLSGQLIAEMCHCSPSSVRRTILERMEPHYRVAKLP
                     KHLCFDEFRSIKSVMSFICCDAETHQIVTKLQDRLSPTIVDYFESRYSKAERECVQSV
                     VIDLNAQYQSFIYRLFPNANIIIDRFHLVQLAGRALDNCRISILKQLDKQSQEYKIMK
                     SHWKLFHKKAEDLHPEEVVFLRGVKQYMTRQNAVDLITSKFSKFAEVYQTYQDITKAL
                     NERNSELLESTILDYQKTNTEMDTAIQTLRQNRKYVLNSAKFEYSNGPLEGINRKIKT
                     LKRTCYGFANQKFFFLRIDCIFS"
     gene            18776..18997
                     /locus_tag="VYR58_000746"
     CDS             18776..18997
                     /locus_tag="VYR58_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621943.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            19114..19611
                     /locus_tag="VYR58_000747"
     CDS             19114..19611
                     /locus_tag="VYR58_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEV3621944.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            19586..20092
                     /locus_tag="VYR58_000748"
     CDS             19586..20092
                     /locus_tag="VYR58_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV3621945.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            20076..22523
                     /locus_tag="VYR58_000749"
     CDS             20076..22523
                     /locus_tag="VYR58_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV3621946.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            22526..24703
                     /locus_tag="VYR58_000750"
     CDS             22526..24703
                     /locus_tag="VYR58_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV3621947.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            24700..25701
                     /locus_tag="VYR58_000751"
     CDS             24700..25701
                     /locus_tag="VYR58_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEV3621948.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            25698..26633
                     /locus_tag="VYR58_000752"
     CDS             25698..26633
                     /locus_tag="VYR58_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV3621949.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            26878..26994
                     /locus_tag="VYR58_000753"
     CDS             26878..26994
                     /locus_tag="VYR58_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEV3621950.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            27010..28929
                     /gene="tet(M)"
                     /locus_tag="VYR58_000754"
     CDS             27010..28929
                     /gene="tet(M)"
                     /locus_tag="VYR58_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEV3621951.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            29048..29215
                     /locus_tag="VYR58_000755"
     CDS             29048..29215
                     /locus_tag="VYR58_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEV3621952.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(29275..29628)
                     /locus_tag="VYR58_000756"
     CDS             complement(29275..29628)
                     /locus_tag="VYR58_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV3621953.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            30133..30555
                     /locus_tag="VYR58_000757"
     CDS             30133..30555
                     /locus_tag="VYR58_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV3621954.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            30552..30782
                     /locus_tag="VYR58_000758"
     CDS             30552..30782
                     /locus_tag="VYR58_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV3621955.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            31243..31446
                     /locus_tag="VYR58_000759"
     CDS             31243..31446
                     /locus_tag="VYR58_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEV3621956.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            31528..32745
                     /locus_tag="VYR58_000760"
     CDS             31528..32745
                     /locus_tag="VYR58_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV3621957.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(32907..33509)
                     /locus_tag="VYR58_000761"
     CDS             complement(32907..33509)
                     /locus_tag="VYR58_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3621958.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQIIYGASLIS
                     FLWMYGQRKQVAKVNMETRIKWIGIGFVSLLIISLYFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLFNKNKV"
     gene            complement(33512..33745)
                     /locus_tag="VYR58_000762"
     CDS             complement(33512..33745)
                     /locus_tag="VYR58_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV3621959.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            complement(33758..34138)
                     /locus_tag="VYR58_000763"
     CDS             complement(33758..34138)
                     /locus_tag="VYR58_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621960.1"
                     /translation="MIDLYLSKNNHRNQLLLEFFQNYGIEVSCHSISEMTRDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(34131..34580)
                     /locus_tag="VYR58_000764"
     CDS             complement(34131..34580)
                     /locus_tag="VYR58_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621961.1"
                     /translation="MKALNKESILYCDELETELHDAEMMQLDEQIFLMPNYPCEFEVT
                     FLDYYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFIDDNHNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKSINFSNLLDSLIVSEYQMEPNLWEVSHD"
     gene            complement(34564..35922)
                     /gene="dcm"
                     /locus_tag="VYR58_000765"
     CDS             complement(34564..35922)
                     /gene="dcm"
                     /locus_tag="VYR58_000765"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEV3621962.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARKSYKSIFQT
                     EGEIEFHDIRDVSDAEFKKLRGKVDIICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQLLNSKDFGVPQNRE
                     RVFIIGHSRKRGTRLLFPFRREGQTTNSETLKTLGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLDKRQNGRRFKENQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYHVAGVLIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     AK"
     gene            complement(36021..36800)
                     /locus_tag="VYR58_000766"
     CDS             complement(36021..36800)
                     /locus_tag="VYR58_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV3621963.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQVENETAPVSHSAPRETEVSETKYSE
                     TDSLFIEDEEDRNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            complement(36797..36970)
                     /locus_tag="VYR58_000767"
     CDS             complement(36797..36970)
                     /locus_tag="VYR58_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621964.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLTLKELGGAL"
     gene            complement(37179..38540)
                     /gene="rlmD"
                     /locus_tag="VYR58_000768"
     CDS             complement(37179..38540)
                     /gene="rlmD"
                     /locus_tag="VYR58_000768"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV3621965.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLFRRFDLKPYDEKEHSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVECVVLLQR
                     KKG"
     gene            complement(38614..39588)
                     /locus_tag="VYR58_000769"
     CDS             complement(38614..39588)
                     /locus_tag="VYR58_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV3621966.1"
                     /translation="MRKKLFLTGAAVLWAVTAMNSAHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(39662..40276)
                     /gene="pmp23"
                     /locus_tag="VYR58_000770"
     CDS             complement(39662..40276)
                     /gene="pmp23"
                     /locus_tag="VYR58_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV3621967.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(40276..41250)
                     /locus_tag="VYR58_000771"
     CDS             complement(40276..41250)
                     /locus_tag="VYR58_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV3621968.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(41258..42514)
                     /locus_tag="VYR58_000772"
     CDS             complement(41258..42514)
                     /locus_tag="VYR58_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV3621969.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(42576..43007)
                     /locus_tag="VYR58_000773"
     CDS             complement(42576..43007)
                     /locus_tag="VYR58_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3621970.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(43009..43611)
                     /locus_tag="VYR58_000774"
     CDS             complement(43009..43611)
                     /locus_tag="VYR58_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV3621971.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(43595..44434)
                     /gene="prmC"
                     /locus_tag="VYR58_000775"
     CDS             complement(43595..44434)
                     /gene="prmC"
                     /locus_tag="VYR58_000775"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV3621972.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(44434..45513)
                     /gene="prfA"
                     /locus_tag="VYR58_000776"
     CDS             complement(44434..45513)
                     /gene="prfA"
                     /locus_tag="VYR58_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV3621973.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(45510..46100)
                     /locus_tag="VYR58_000777"
     CDS             complement(45510..46100)
                     /locus_tag="VYR58_000777"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV3621974.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            46223..46405
                     /locus_tag="VYR58_000778"
     CDS             46223..46405
                     /locus_tag="VYR58_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV3621975.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            46541..47914
                     /gene="mnmE"
                     /locus_tag="VYR58_000779"
     CDS             46541..47914
                     /gene="mnmE"
                     /locus_tag="VYR58_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV3621976.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIVQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEQLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(47961..48896)
                     /gene="dapA"
                     /locus_tag="VYR58_000780"
     CDS             complement(47961..48896)
                     /gene="dapA"
                     /locus_tag="VYR58_000780"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV3621977.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(48952..50028)
                     /locus_tag="VYR58_000781"
     CDS             complement(48952..50028)
                     /locus_tag="VYR58_000781"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV3621978.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(50614..50686)
                     /locus_tag="VYR58_000782"
     tRNA            complement(50614..50686)
                     /locus_tag="VYR58_000782"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(50651..50653),aa:Thr,seq:ggt)
     gene            complement(50786..51295)
                     /locus_tag="VYR58_000783"
     CDS             complement(50786..51295)
                     /locus_tag="VYR58_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV3621979.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(51293..51389)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            51418..51849
                     /locus_tag="VYR58_000784"
     CDS             51418..51849
                     /locus_tag="VYR58_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV3621980.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            51931..52308
                     /gene="mscL"
                     /locus_tag="VYR58_000785"
     CDS             51931..52308
                     /gene="mscL"
                     /locus_tag="VYR58_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV3621981.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(52350..53444)
                     /gene="hemH"
                     /locus_tag="VYR58_000786"
     CDS             complement(52350..53444)
                     /gene="hemH"
                     /locus_tag="VYR58_000786"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV3621982.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            53599..54822
                     /gene="pepT"
                     /locus_tag="VYR58_000787"
     CDS             53599..54822
                     /gene="pepT"
                     /locus_tag="VYR58_000787"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV3621983.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKEQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(54858..55487)
                     /locus_tag="VYR58_000788"
     CDS             complement(54858..55487)
                     /locus_tag="VYR58_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621984.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            55452..55673
                     /locus_tag="VYR58_000789"
     CDS             55452..55673
                     /locus_tag="VYR58_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621985.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(55782..56258)
                     /locus_tag="VYR58_000790"
     CDS             complement(55782..56258)
                     /locus_tag="VYR58_000790"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV3621986.1"
                     /translation="MTPNNGVSAADDGYVFNPNDIVRDTGDAYIVRHGDHYHYIPKSS
                     LNNPPSHSNTEEAGSSSSSVLSNPSLHVHHEEEDGHGFDANRIISEDSEGFVIPHGDH
                     NHYIKVQTKGYEAALKNKIPSLQSNYQPGTFDEKAVLAKVDQLLADSRSIYKDRLS"
     gene            complement(56298..56438)
                     /locus_tag="VYR58_000791"
     CDS             complement(56298..56438)
                     /locus_tag="VYR58_000791"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV3621987.1"
                     /translation="MLEITLKSPYQFAHILFQPTIVPHGGHYHFIPESDLSAGELAAA
                     KV"
     gene            complement(56482..57034)
                     /locus_tag="VYR58_000792"
                     /pseudo
     CDS             complement(56482..57034)
                     /locus_tag="VYR58_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT        17569 a        11231 c        10630 g        17604 t
ORIGIN      
        1 aacttaatta ctatgttttg aatttaagaa aatacaactc ccagttagta aaaaactgta
       61 tcatcgatga cattaatatc ataacacaat tatgttcatt tctattttct ttcccttata
      121 cgcaatttac gccaagtcac ctaacacttt ttgtaaatga ttctcaaatt ttaaagccgt
      181 ctgattacta tctaccaatt tcatggttgc aatacacttt ctcatttcca aaacagcgta
      241 tcgattattg tttttcttta aatcatataa atttttagta tagtgaagca ctagcttttc
      301 atacatttca gtctctgaaa agttacaata ctttagctgt ttttcaaaat aaagagcatc
      361 catcaattca ttgcgttcaa tacaggtgat ataagcattg agcaacatag ttgctaataa
      421 gcgtctatta ttaggaattt ctctataaaa ctccgaacga tggcacattt ctttggctaa
      481 aaccatcatt gttttatgat ttaaaacatc tattgtattc ataaacagta gcaattcata
      541 gtatccccag tattctacag aaaacaagta atcactgata ataccaattt cttggtctgt
      601 tactaaaatt tcttctaaca aatcctgtaa tcttatttta agcaaaattg tgttaaatga
      661 atcgaatggt tcttttttat ccttcttttc tatctggcta attaatagct ttttcattcc
      721 gtctatatca cactttgaga ctaaataccg aattttttct aaaagttcat taaagtcatc
      781 tctacggaaa tcacgtacag cgtaaacaaa ttcttcgata ggcatgtgta ttgcatctaa
      841 ggctaaaaga aatttactga tggttaaatc agcttcatca tgttcaaatc ttgagagatg
      901 ggaacttgaa agacctgatt ttgcaacatc ttttaaagac aaaccgcgag attctctaaa
      961 ttttttaaaa atttttccat atttcattcc agttacctcc taatttgcgt ataagggaaa
     1021 tttctccaca atctttaaaa atattatatc atataagaaa acgaaaagag gtatttatca
     1081 tgaataaaaa agcatggttt agtttgttat ttgtaatact tgaaagtatt atcgttatcg
     1141 gagtaggtta gtgaaatgca ttaaattcta gtgatatgaa agtcactaga atttttttaa
     1201 ttcaatgaaa aaaagagcga taaaaagtca ccctctccct agttttatat agcattacta
     1261 ctatttttgt cggtttattc tggtgtctgc caccgcttgg tccttacgtc caagattgct
     1321 atcggatttc gttctggtgt ccgccaccgc ttggccctta tgtccaagat tactatcaga
     1381 ttgaccatga gccgaccact catttacacc attattataa cgaatatgag ctacaaatgc
     1441 aagagaaaaa cttatttggg atttatacac tatagaaaac atacactatc tttagattga
     1501 acttttgttc aaaataagct ataatgaatt taagtagaaa caggaggtag aacaaatggc
     1561 tacaatcagt ttaacacgtg atataaaact aacaaacgaa gatgctctaa aaattcttaa
     1621 tcataaacca tctaaaaagc tacaagccgt cttgaaatct attgaatcac aggacgctac
     1681 cgctccaacg aaaaataaac tcatttcaaa gtatctgtaa gatgacaatt caagtaacac
     1741 cacttaagca atatcttgaa aacattcaag tgctagctcc tgataaaact gagaaacaag
     1801 ttcaggagct atttaaaact atcattttag aaaatgttga tttcaacggt aatgaagaga
     1861 tgttgactta tctatctgat aaagccccca attttgaaaa acaacatcgt tctcgtaatt
     1921 ttatcgttga agaaactgaa acaaataaca tcataggatt ctttagttta tctctcaaag
     1981 ttgttgatat ttctgattta gagaaatcct taaaaaagaa actcgtccta aaagggaaaa
     2041 gtcccaaaaa tattgattat ctccctgtgt tacttatcgg tcaattcggc aaaaacacaa
     2101 atctaaataa actatcagga caagagttat ttgaaattgt aattcaaaaa attgaagaat
     2161 ttcgagcaat tgtaggaact cagatggtat ttttagatag tatcaatcat cctaaagtca
     2221 ttcaatttta tgaacagttc ggatttgttg cttacagtca attgattaaa gacgatcatc
     2281 aagtaactta tcagcctatg gcattaaata tgtcactcta taaaaaataa gaatcatgtc
     2341 acctaaactg atgacatgat tcttttattt caccgtataa gcaaaactga tggcactatc
     2401 tgcttgcgag atttttctaa aggtatagtt agggttgcca ccatagttgg tttcagacac
     2461 aaggaaagaa ccatcatcat agactttctc tacaaaagcc acatgaccgt agatggctgg
     2521 tgtgccatgt gtacctccca caaaagaaac aatagcacct gctcttggta tagagcccgt
     2581 ttcccctcca agacttgaag ctgtcgaaac ccaatcctga ccatttccca tggtattaat
     2641 gattgaaatc ttttctccat tacttccttt taattttaag cctaactggt tcatacgagc
     2701 cgcaactccc catgtacatt gtccataggc ataggccata ccatctccac caccaggaac
     2761 agaatgatca tacaagtccc cacgaacccc ttcaagggat tgtgggtcac tctttgcttg
     2821 tcctccgttt gtttggctaa agcctttttc aatttggtaa taccattccg ttgctctggt
     2881 ttgtctttcc agtagtttgt caccagaatt tccctcccaa taggtgagga agagttgggc
     2941 gagattggct gcactgcccg tatttttaaa gaaatctttt aaccaacttt gatagtaagg
     3001 actatcccca tgaagcataa aatcaagttg gaggtctaaa tcataccact tcttattttt
     3061 gctatgtgca taattcaata aagctgtatg acgtgttgaa ccatctgcag tatccgtcca
     3121 ttgacctaac cccaaacctc tatgaaggat attaggataa gcaccactat aaatggctgg
     3181 acctccaatc gctaaccagg tttcatcatc ccatgaggaa gcggtagcgc caactggagg
     3241 agataaataa tctccctcag ctcgtttagg attgatagaa gactctaccg accaatttcc
     3301 taaaatagct gcaatggctt ggggacttgc cccttgagat ttcaaaaact cataaatatg
     3361 tttcgctcgt tcaaactcat ccccaccaaa ctgaccaatg gcaggtaaga tagttgtctg
     3421 aagttgaatg acttttggaa aataaaattg cggattgacg tacaccaatt tttctttctt
     3481 gttcttaaac ttttgatagg aaactttcaa acctgtatcg tctggtgttt caccaataat
     3541 atcacccgtt aggactcttg tcccctcaat cgcacggcca ttatgaatag aatacaaggt
     3601 taatcgactc tcattctctc cttttccgtt agtgagaata acattgtcgc catctagaga
     3661 tacaactcca tccattggtg cgacaattgc ttggtgagct ttagcttcta gtagaatgta
     3721 ctcctgaaga gtaggttttc cgtctaaatc atagtatcca taacgataag tcatggttaa
     3781 actatcttcg ttacttttcc cttcaaatgg attgtccaat tcctgcatgg aagcatacac
     3841 accttcttct tttagttcct tcatttcctc ttgatcgtct ttcgatagtt tatacttagg
     3901 agtttcataa aggtcttgca tggatttcaa atcttcccca tcgtttaaat catgccacaa
     3961 agtagataga taatccttgt aagtttctga actaaataag tgaactggtt tgtgtaactc
     4021 atagtcatgg aatttaaagt tcatataccc catcacatca tcaacttttg tgtaataggt
     4081 aattcctttg tcattggttc gggtatgttc tgcgtcttcc caagttaggt gggtataagc
     4141 ttttgttaat tcaaattcat cttgttgaat taaactagca gatgaaaatc ctaaaaagaa
     4201 gctcatcata agtaaaagaa gaaagactat tcctccaact atccaggttg caggattccc
     4261 agccgcaaat gtaaagaagg aaaaggctgc ttttagtttt tgatagatat ttcgtacact
     4321 tgtaaggcct tgtttcttta attttcgata ccgattttta aaggaacttg gattatcttt
     4381 cgctagtttc catccttttc catccttaaa atgatggtat cgctcttttg tgttggtcag
     4441 tcttttcttg gtaaaacgac ctgttgcttg tcctgttttg acactagctt ttccaagatt
     4501 ataagaaagc cgactgtagc gtttcccttt tctaatggtc tcttgaagtg tgcgatagcc
     4561 ttctaaatct tcattttctg aagctaactc tccaccttca cgtccaagga cataaaggaa
     4621 agttttggct ttcctactaa cctttttgga tttataggct tgtttagtag attttaaatt
     4681 ttctttggcg tccttgactt ctttcttagc ttttaattct tctaaactct tcccttgaaa
     4741 gaaaaaattg gattttgctt ttgtttcctg accataaaga aatttttgat tggtttttct
     4801 ttctttacga ctctcttttc tttcttcttt tgcttctacc ttggcttctc taaattgctt
     4861 cttagctatt ttcaatcgtt tcctagcatg aggtaatcgt ctgtctctta attctttgcg
     4921 attcaaaaga gatggaggac tattttgaag aatatgattg tagtcttcat ttgcttgttt
     4981 tactctctcc tttgaagcct ctctcatctc ctctagcttt tcttttatct cttttttcca
     5041 tgctttttca tccagtacag cggaatcttt tttctgtttc cttacctcct tctttccttt
     5101 tttcaagaat tttttctcat cttttaggct tcttctaaat gcctttcggg cacgtatgat
     5161 ttttctttta tccttcattc tacttcccct taattagaag ccattttatc aggatccgta
     5221 ctcatgatat caaacaattg agtaccttga ggaatcttat ttttaaaggg tacgacaact
     5281 gaaccagctt ttatcagtcc tgcccctttt tctggattga caaggtattt ttcgagttct
     5341 tttgacaagc ctaagagttg aaccagttct tctcggtcat tttttgcttg cttgaggaga
     5401 atcataaatt cactatttgc aataatccgt ctaccatttg gatctaacaa taaggtttcg
     5461 acgttttgag ttatcccagt cggactagct ccatattttc tgacacgact ccacaattta
     5521 aagaagaaat cactggcata tttatctaat aagagaagct gcatttcatc aaaataaatc
     5581 caggtcttct tccctaattt ttggttccga acaacacgat tccatatctg atcaaacact
     5641 accataagag cgatttgttt cagctcatct cctaactttt taacgttata gattaagaag
     5701 ttagatcctg tctgaatatt ggtcttatga gaaaaaatat caagagaacc ttcgacatac
     5761 agttccatat caagtgccaa attctgcgct tcttcttctg gttgttgact caagacaaag
     5821 acccattctt ccaaagaagg ctctttaaat gactgatagg tgagtctggt gactcggtcg
     5881 ataatcgatt tttctcttcc atccattttc ctatccaata acttgccgat aaaggataaa
     5941 agaaattctg attttacctt aacaggatcc tcatccatat tttcatcaga caagtcaagt
     6001 acattgagat aggtttggga atctggcgca atatcaatca tttctccccc aaaagctcgt
     6061 ccaatgacac tgtattctgc ttctggatcc acgatgataa tttcagtatt ttcaccagat
     6121 tccttgattt tggtcgtgat aatctcatgc ttagttgcca tccctttccc agctccagat
     6181 gtccctaaaa tcagaccaga cggtgtattt aataagcttc gatcaatagt aataatattg
     6241 cttgagattt gattgatacc gtaatatttc ccactgcggt cttgtaagtc tactgaagtc
     6301 caaggtgagt tcactgctac attagatgtt aataaactcc gtgatactcc ctctaaaaaa
     6361 tcacaaccaa atggcagcaa actattaaag gctgcttctt gcatatatgg aagtttatca
     6421 atcattaggt catttgagcc ggccacttgt tgaatcgtat ctagagcttg tttgagttct
     6481 tcttcatcct gaccaaagat cccaatcaag aagaccgttt gaaacagttt atcacctgtc
     6541 tcggtcatgg tttttaaaag ttcttcagct tcatcgatat tactttctaa tacatgacct
     6601 actttttcca aatagatacc tgtacgagct agtttttgtt gttccccaat cttttgggat
     6661 tccatcaagg tcttctttgt tcgtagtttc ttcatggcat ctgccttggt cgaactttga
     6721 gcatgaaggc ttacaatcaa ttccaaatct ccttgcataa ggtctcgaat aaactgatcc
     6781 cctaattcca tgccgtagtc tctgacatag acaatctgta ataagcggtc attgatttgt
     6841 aggtaattct tgtttttaaa atccaagaga ttaggggcta tgaagtgacg agttgtctga
     6901 ccagatctcg ttaaatcacg gtaagaaaaa ggaagatggt gttctcctct aagcatgtcg
     6961 gccaacaagt tcacacgatc ttctccagcc aaggattcaa atcgagcatc aatttctgag
     7021 aaaccactct tgaaatattc tcctatttga gacaaggaac gataggcttg tttgggatta
     7081 gaatcctttc ttccaaagct aatcagtttt acagccgaaa agttattttc accactatct
     7141 aaattctgat tcatcatccg attcaattct ttacgatagg tatcatatcc atcttctttt
     7201 tcctcataca aaacactttg tctaaacttt tctaaattca atcttttatt aaagatagtc
     7261 aattggaagt tggtttggtc atctagtgag ttaatcaaat cagaatactt ctcaatgatt
     7321 gcgcccttat cttctaaacc aacggtctgg taattgacat caccaagtaa atagctttgt
     7381 gagaaataat cttcttttac ctgcatcaga ccattttgat acagggcttg ataggaaaga
     7441 gtattagccg ttgagggtaa cacttcctct tttttccctt taacttcttc ctttttatta
     7501 gtcattgaag ttttttgttt ctttaatgta tttgattttc ttttcatgtt caggtccttt
     7561 ctttcctgta attgtgcgta ggggaaccgt taattcaaaa tgaagacggt atttcaaata
     7621 atgttcaaaa tataaatcat tgggtttata gactccaaaa agcattaggg ggatggtaaa
     7681 agcaaacaca aaaccgtaaa caaaccaatc tccaaattgc cagaaaaaga gattcaagcc
     7741 caaaacaata attgtgacaa taaaggctgg taaaacaaag atgatttgtc ttgtggtgaa
     7801 acctaaccaa gccctgtgtt ggtattttga gatgtcttta aagacacatg tattcatgac
     7861 tttcctttct aaaaaggcta agaagcaatc acttcctagc ctttatctaa ttacatacct
     7921 aagattgagc gagccgtacg ttgagaacca acgagggcaa taatcagtaa gatagcttgt
     7981 actaaactac caaacataat cgcaagtgat tgcaagactc ctgcaccatt tgaaacagct
     8041 attttcccag cagattcaaa caaaggaaca agagaaacaa tcagaaaaat gagaacccct
     8101 tgtaccgcat agaccataat attttttaaa tagccaatac caatagactt ccattcatca
     8161 cttaaaaatg ttggaatcgt aagaggggca aatgggatca taaggtagag ttgaataaat
     8221 cgaatagata ccaaaagatt aaccatggct gcacttacta tccgaacaag ccagataagg
     8281 agagcgaaaa agcccacaat catccggcca ataaatcctg aaccttttaa tccagagagt
     8341 gtatcatact tcgccccacc gtgagccaca atcgaggcca cttgttcgat ggcgtgactc
     8401 gcaatcccga tgatagcttc tactataacg gtagtattgg taatgaccac tgcgaccata
     8461 atataactaa tcaacatcgg cgctaatgct tcaaaggtca tcgctccacc agagttagca
     8521 atcttctttg ccatcttcga aaattctaag atgagaacaa ctgataaaat cgcaactcca
     8581 agaggctgca tgacactttt agtaatacta gacatataag tccaaactgt tggattgtag
     8641 ctagataggg atttaatcag atctaccgta gattgtaaat ccacattaaa tccttcaaat
     8701 aaattttcag ctgatatttt ttcagatgca aggtaaacaa agggtgagac taaactaaga
     8761 ttcatgtcat tgtttatcct cctaaattga aatctgggtt acaaaggctc cagcagcccc
     8821 taccataaca ccaccgacaa tttcaagaat ggcattccga acacctggtc caccatcttt
     8881 aatgttggtt gcaaggttga caatccccac aacaacgaga aaggcaccaa ctgcaatcaa
     8941 tcccttctgt aacaaagaca tagcttgtgc aaacatagca cttgcgtcta ctccataaac
     9001 aaaaccttta aaatgcgtaa tcatctattt cctcttttct atttttattt taaactagat
     9061 tcaaaagtta aatcacgaat tctaaggtcg tcaagataat tttcttgtct ttgattcaaa
     9121 ggattgattt gatagttcca ccaccgttca tcgctttctt gattagctag gtacttccag
     9181 tttggatgct tagtggaatt gtattttttg cttttaaaga caggcatatt ggcaattcga
     9241 accaagcatt catgccgttt catatttccg acctcatcgg gtgtcattaa gtcacgagca
     9301 atcttttgat gagaaaggga tcctgaacct gtttggccaa aggaacgact agtatttcga
     9361 acatcaatgg tttgtttacc gagtaagcca ctcataaatt taaaggtatc ttcatcatta
     9421 ccacctaagt agactaagct atcacagttc cccaaaatgg ttttccaagc ttctttttct
     9481 ttatagagcc cttgaagttg ggcaatattt tgaagaatag gaacgagact catatttcga
     9541 gaacggactg ttgaggtttg ttcagcaaaa tctggaattt ctccgatatt tgcgaactca
     9601 tctaagtaaa ctctcacatg aagaggcaat tgacccttaa aatcaatatc tgcttgtctt
     9661 gttagggttt gaaatacggt tgaaaaaaag agggctgaaa gaaagcgaaa ggtactatcg
     9721 ttatctggga taactaagta aaccattgat ttttccttgc cccatgtctt catatcaagg
     9781 gtatctcttt tggtcaagtc catgacactt tgaatattga agagggcaaa tttagcagtg
     9841 gttacagcta taacagaatc cagagtctta tccttataat tttgaaaatc tgcccaattt
     9901 cgcatggtaa aattttcagt cccatacttt ttagcataat tttcaaatag aatttctaag
     9961 acactttttt cctggttttc acccttggat aagtgtttaa tgagttttga gatttcagca
    10021 aaacttggat aacgacctcg tttttttcgc tcttccactt cttttttttg acgtttcaac
    10081 aagttttgat attccttttg acttaaacga ctttcttcta tgagctgttc tcttgtttta
    10141 ggtggattat agaaatcgac taagtaagag gctaaagctc gaaccaaagt catagaagct
    10201 tcatcccaaa atggatcact tcgggagcca gagcctttgg tgttattaaa ataaacagtc
    10261 agcatgcgat tcaaatcgtt ttctgtttct atatagcgaa aaggattaaa gccatctgag
    10321 ttcttcatat tgactaaatc taacaccttt acttggtagc catgttctaa aaagagtttg
    10381 cctgttttct cggccaagtg atctttagga tccactacaa tattagaact attcatctga
    10441 atcagattgg gtttcacaaa gcgaaatgtc ttcccacttc ctgaacctcc aatcaccgca
    10501 atattcttat ttctatcata ttggggtggt tttttatcta ataatgtcaa acgaacatct
    10561 tgtgctaaga tcgtatcatg agaaaattcc ttaccgtaaa agagcttctt ttcttttaga
    10621 gttccaaaac gggcgctccc gtattctacc ccttctcggt attgtttttt accagtctct
    10681 agatagagat aaaccagtaa catcatcaca aaacctagta gaaaaaaagc acttgatttt
    10741 ccagtaaaag aaacattcca tggcgactga agaacttcat cttgaccttc catcagaaga
    10801 tgagtccatt tatctaaggt atttccagta taggaatcat acaaaagcgt caaacgatga
    10861 aaaagatagc ctagtaagat acctaacagt gagaatagta ggaatttttt tccactgtac
    10921 atcatctcac catctctttc tgtttgacgg ctccttcttg tctaaaggta atttgggatt
    10981 tagcttcatc aatagcatca tctaatgact tatccatggt aaaatcagct aatttctccg
    11041 gatcattaac cattttttct aaaagatggt ctaaatgatt gtctaaaatc gaacggtctt
    11101 tcgcgtagaa atgtagagaa tccccttgcc aagcgatggc taaaggaatc tcttcttttt
    11161 ctaaaaaagc tttaaatttc tctatatcaa ttggtttgtc taaaaaatct tttttcagat
    11221 taatcgtatc aatcgcatag ggagattgta gcaattcttc taatttctgc actcctatct
    11281 tataggcgga atcctgtgct aaagcctgac gtctagacca ttctagaatc tttaaaagac
    11341 tttttacagt aaataaaaga ctacgctctg catattgaac tgccattcgt tcctgttgtt
    11401 cagaggacat ctgatgcctc cttcttcaca aatagcagct ttccttcttt ataacgataa
    11461 gctatcaatt tctgacgttg cttaatcgac ttgacaacct tcagtagatc tctcgaataa
    11521 ggttctcgaa gagtgacttc tactgccttc ccatcaacga taccaacacg tttaaattca
    11581 atgtagtctt ttttgagatg tcctaagccc ataccaaaag gaaagtgatg aatcaattgg
    11641 atggtacaac cacctttatt tcccatttgt ttcaaatcat acaagtttac taccttcatg
    11701 attaactcct ttatctagtt tgtcgcatcg tttaagtctg gtaacgataa actccgtgtc
    11761 tgttagaaaa ttctcacaca cgtcttgtgc cagttgccct tcacagggaa atactctcag
    11821 tccctactta cacaggcacg ctaatcaaga cggagtggat tcaattttca aagaacaggt
    11881 agctttatta tagagaagag tagttgaaat ttttatcaca ttttttattt ttctgtagag
    11941 ctaaattcat actaaacaaa gattttgaaa taaaagacta acattgttac ataacgttag
    12001 catttcattt ccctaaaata agctaatttt gtctaaaaaa tagcataaaa atctagttat
    12061 ccgcataaaa actggactta tcacacttta tcaaggtcaa aaccactcaa tttactacta
    12121 atttactact tatgaatgag ctttgatacg acgatttatc cttgaaaagt gaagatataa
    12181 agatacttcc aataaaattt gaatatttaa taggtagaca cttcaaaaaa tgaggtgtct
    12241 atttttttac ccgattttga aaggaagtga acttatgaaa acaaaaaatc aagaatcaaa
    12301 aggtcgttcc ccactcttta agaccatcaa acattcattc agccaataaa aaagaaagga
    12361 taggtaaaaa tatggaactt aaatttgtga ttcccaacat ggaaaaaaca ttcggcaatt
    12421 tagaatttgc tggcgaggat aaagtcgttc agcgaagaat caacggacgg ctaactgtct
    12481 tatcaagaag ctataatctc tattctgatg ttcaaagagc agatgatatt gtggtggtgc
    12541 ttcctgctga agctggcgaa aaacatttcg gctttgagga acgtgtgaag ttagtcaatc
    12601 cacgtattac cgcagagggc tacaaaatcg gcactcgtgg ttttacaaat taccttttac
    12661 atgctgacga catgataaaa gaataaagaa agagaggaaa aatgatgaga ttagcaaatg
    12721 gcattgtatt agataaagac acgacttttg gagaattgaa attctctgct ctacgtcgtg
    12781 aagtgagaat ccaaaatgaa gacgggtcgg tttcagatga aatcaaggaa cgtacctatg
    12841 acttaaaatc caaaggacaa ggacgcatga ttcaagtaag tattcctgcc agcgtgcctt
    12901 tgaaagagtt tgattataac gcacgggtgg aacttatcaa tcccattgcg gacaccgttg
    12961 ctactgccac ctatcaagga gcagatgttg actggtatat caaggcagac gatattgtgc
    13021 tgacaaagga ttctagttca ttcaaagctc aaccacaagc aaagaaagaa ccgacacaag
    13081 acaaatagtc gctaggtaga aaggagactt tttcgcatga aacagcgtgg taaaaggatt
    13141 cgcccatctg gtaaagattt agtctttcat tttacgatag cgtcactcct gcctgttttc
    13201 ctgctggttg tcggactgtt tcatgtgaag acaatccagc agatcaactg gcaggatttt
    13261 aacctatcac aagcagataa gattgacatt ccctatttaa ttatcagttt cagtgtcgca
    13321 attcttatct gcttgctggt agcgtttgta ttcaaacggg ttcgctatga tacggttaaa
    13381 caactttacc accgtcaaaa actggcaaag atgatacttg aaaacaagtg gtatgaatct
    13441 gaacaggtca aaacagaggg tttctttaaa gatagtgctg gtcgtacaaa ggaaaagata
    13501 acctacttcc ctaaaatgta ttatcgactt aaaaatggct tgatacagat acgggtggaa
    13561 atcacgctgg gaaaatatca agaccaactc ttacacttgg aaaagaaatt agagagtggc
    13621 ttgtactgtg agctgacgga taaagagtta aaggattcct atgtggaata tactttgctc
    13681 tatgacacca tagccagtcg tatttctatt gatgaagtag aagctaaaga tggtaaactt
    13741 cgcttaatga aaaacgtatg gtgggaatat gataagctcc ctcatatgtt gattgctggt
    13801 ggtacaggtg gcggtaaaac ttactttata ctgacactga ttgaagcctt gcttcataca
    13861 gattcaaaac tgtatattct tgacccgaaa aatgctgatc ttgcggactt aggttctgtg
    13921 atggcaaatg tctactatag aaaagaagac ttgctttctt gcattgaaac attctatgaa
    13981 gaaatgatga aacgtagtga ggaaatgaag cagatgaaga actataagac tggcaaaaat
    14041 tatgcttact taggtctccc ggcacacttc ttaatctttg atgaatacgt cgctttcatg
    14101 gaaatgctgg gaacaaaaga aaacaccgca gttatgaata agctgaaaca gattgtcatg
    14161 ttaggtcgtc aagctggctt ctttctaata ctggcttgtc aacgtccaga cgcaaaatat
    14221 ttaggcgacg gaatccgtga tcagtttaat ttcagagtgg ctttaggtcg tatgtctgaa
    14281 atgggctatg gcatgatgtt tggcagtgac gtacaaaagg atttcttctt aaagcgaatc
    14341 aaaggtcgtg gctatgttga tgtaggaaca agtgtcatat cagagtttta tactcccctt
    14401 gtaccaaaag gatatgattt cttggaggaa attaaaaagt tatccaacag cagacagtcc
    14461 acgcaggcga cgtgcgaagc ggaagtcgca ggtgtggact gatcttgctg gctggtgtgg
    14521 caatagccac gccagcactt aaccccccgt atctaacagg ggggtacaaa tcgacaggaa
    14581 acagtcaaaa aaacattaga aaatcctttg gttacaaggg atttacaaaa tttcagcgta
    14641 tgtcaaatgg gctttaaaag ttgacatacg cctttttgat tggagggatt tttactgaat
    14701 gaacaaactt ggttacagca tttaaaagaa aaacgcttgg cttatggact atctcaaaac
    14761 cgtttagctg ttgcgactgg tattacaagg cagtatctaa gcgatattga aacaggaaaa
    14821 gtcaagccat cagaggattt acagcagtcc ctttgggaag ctctggaacg cttcaatccc
    14881 gacgctcccc ttgaaatgct gtttgattat gtaagaattc gctttccgac aacagacgta
    14941 cagcaggtgg tcgaaaacat cttacaactg aaactgtcct attttcttca tgaggactat
    15001 ggtttctatt cttattcaga gcattatgct ttaggcgaca tattcgtcct ttgctcccat
    15061 gaactggaca aaggagttct ggtggaattg aaaggtcgtg ggtgcagaca atttgaaagc
    15121 tatcttctgg cacaacaaag aagctggtat gagttcttta tggacgtttt ggtggctggc
    15181 ggtgtgatga aacgccttga ccttgccatt aacgataaga cagggatttt aaatatccct
    15241 gtactcactg aaaagtgcca acaggaagaa tgtatctccg tcttccgcag ttttaaaagc
    15301 tatcgcagtg gcgaactggt acgcaaagag gaaaaggaat gtatgggaaa caccctctat
    15361 atcggttcat tacaaagtga agtttatttc tgtatctatg aaaaggacta cgagcagtac
    15421 aagaaaaatg atattcccat tgaagacgca gaagtaaaaa accgttttga gattcgattg
    15481 aaaaatgagc gtgcctatta tgcagtccgt gatttactcg tctatgacaa tccagagcat
    15541 accgccttta aaattatcaa tcggtatatc cgttttgtag ataaagacga ttccaaacct
    15601 cgttctgatt ggaaactgaa tgaagaatgg gcttggttta ttgggaacaa tcgtgaacga
    15661 ttaaaactaa ccacaaaacc agagccttac tccttccaaa ggacgctgaa ctggctatct
    15721 catcaagttg ccccgacctt aaaggttgcg attaaacttg atgaaatcaa ccagacgcag
    15781 gttgtaaaag acattctcga ccatgcgaaa ctgacagacc gacacaagca gattttgaag
    15841 caacagtcag taaaagaaca ggacgtgata acaacaaaaa aaggatatct gtcaaccata
    15901 ccagttgaca gatatccaaa aaaagatata atgggagata agacggttcg tgttcgtgct
    15961 gacttgcacc atatcataaa aatcgaaaca gcaaagaatg gcggaaacgt aaaagaagtt
    16021 atggaaataa gacttagaag caaacttaag agtgtgttga tagtgcatta tcttaaaatt
    16081 ttgtataata ggaattgaag ttaaattaga tgctaaaaat ttgtaattaa gaaggaggga
    16141 ttcgtcatgt tggtattcca aatgcgtaat gtagataaaa catctactgt tttgaaacag
    16201 actaaaaaca gtgattacgc agataaataa atacgttaga ttaattccta ccagtgacta
    16261 atcttatgac tttttaaaca gataactaaa attacaaaca aatcgtttaa cttctgtatt
    16321 tgtttataga tgtaatcact tcaggagaga ttacatgaac aaaaatataa aatattctca
    16381 aaacttttta acgagtgaaa aagtactcaa ccaaataata aaacaattga atttaaaaga
    16441 aaccgatacc gtttacgaaa ttggaacagg taaagggcat ttaacgacga aactggctaa
    16501 aataagtaaa caggtaacgt ctattgaatt agacagtcat ctattcaact tatcgtcaga
    16561 aaaattaaaa ctgaatactc gtgtcacttt aattcaccaa gatattctac agtttcaatt
    16621 ccctaacaaa cagaggtata aaattgttgg gaatattcct taccatttaa gcacacaaat
    16681 tattaaaaaa gtggtttttg aaagccgtgc gtctgacatc tatctgattg ttgaagaagg
    16741 attctacaag cgtaccttgg atattcaccg aacactaggg ttgctcttgc acactcaagt
    16801 ctcgattcag caattgctta agctgccagc ggaatgcttt catcctaaac caaaagtaaa
    16861 cagtgtctta ataaaactta cccgccatac cacagatgtt ccagataaat attggaagct
    16921 atatacgtac tttgtttcaa aatgggtcaa tcgagaatat cgtcaactgt ttactaaaaa
    16981 tcagtttcat caagcaatga aacacgccaa agtaaacaat ttaagtacca ttacttatga
    17041 gcaagtattg tctattttta atagttatct attatttaac gggaggaaat aattctatga
    17101 gtcgcttttt taaatttgga aagttacacg ttactaaagg gaatggagat aaattattag
    17161 atatactact gacagcttcc aagaagctaa agaggtccct agcgcctacg gggaatttgt
    17221 atcgataagg ggtacaaatt cccactaagc gctcgggacc ccttgtagga aaatgtccta
    17281 agtgggatat ctgtcaactg gtatggttga ctaaaaatac ttcctacgaa aatgtagggg
    17341 gtattttttt acgaaaaaat acaatcgatt cttaaaaaga aaaatttttg attggcaaaa
    17401 ccataacaag ttcgttttag ggttttgatt ttgcgattga tgccttctaa aggaccatta
    17461 gagtattcaa atttagcgct atttaagaca tattttctgt tttgacgaag ggtttgaata
    17521 gcagtatcca tttctgtatt ggttttttgg tagtctaaga tggttgactc tagtaattca
    17581 ctattgcgct cgtttagggc tttcgtgata tcttggtaag tttggtatac ttcagcgaac
    17641 ttggaaaatt tactagtaat gagatcaaca gcattttggc gagtcatata ttgtttaacg
    17701 ccgcgaagaa aaactacttc ttcagggtga agatcttcag cttttttatg gaatagcttc
    17761 caatgtgact tcataatttt atattcttgg ctctgtttat caagttgctt taggatagag
    17821 atacgacaat tgtccaaagc gcgaccagct aattgtacaa ggtggaagcg atcaataatg
    17881 atattggcat tagggaaaag gcgatagata aaactttgat attgagcatt taaatcaatt
    17941 acaactgatt gaacgcattc gcgttcggct tttgaataac gactttcaaa ataatcaaca
    18001 atggtaggtg atagacgatc ctgtaacttt gtgacaattt ggtgggtttc agcgtcacaa
    18061 cagataaagg acatcacaga cttaattgaa cgaaactcgt caaaacatag atgcttaggc
    18121 aacttagcca cacgatagtg tggttccatg cgctctaaga ttgttcgacg aacactgcta
    18181 ggagagcagt gacacatttc agcaataagc tgaccagata agcctttacg agctaaaagc
    18241 atgatttgat ttttgagatc actggataag gtttgatttt ctttggttaa attagtaata
    18301 gcaccaaaag tagtatggca tgatttacat ttatagcgtt gtttacgaag ctctagttca
    18361 tatcttctcc catttaaact tgccagtcgt acatgagttt tgcgaaagcc atccttatta
    18421 actgtgggaa agccacagtt acgacaacga ttaatcggat aagaaagagt agctgttatt
    18481 agcgttatat actctttaac agaatcgttg ttgtgttcag cttcttcaac agaaataatt
    18541 ttaatatttt tatctttaat tccaagaata tttaggatag aatcattatg ggacatttgt
    18601 ttaaccttct ttcatgattt ttgtggtgaa ttgattgtat aacgagggga cagcaaatgt
    18661 cctctttttt gtataaaaaa atctggcatg gaatctctat ccataccaga aagtgtatac
    18721 cccaaaaaaa taactcaaat acaaattcat tgaatataga gaggagaaca tttttatgaa
    18781 ttttggacaa aacctttata actggtttct atcaaacgct caatcactgg tgcttttagc
    18841 aatcgttgtg attggcttgt atcttggctt caagcgtgag tttagcaaac tgattggctt
    18901 tttaattatt gcgattattg cggttggctt agtcttcaac gctgctggag taaaagacat
    18961 tttactagag ctattcaatc gcattattgg tgcttaaata aaaccgttct tttgtggaat
    19021 ataagtggtt ttcttatgtt ccgcaaagga atggtacacc aaacgaagtg cggtagggat
    19081 ttttgaatct ctacaaagaa aggacgtgaa tatatggacg atatgcaagt ctatattgcg
    19141 aatttaggca aatacaatga gggcgaattg gtcggtgcgt ggtttacctt tcccattgac
    19201 tttgaggaag tcaaagagaa aatcggcttg aatgatgaat atgaggaata cgccattcat
    19261 gactacgagt taccctttac ggttgacgaa tacacttcca ttggcgaact caatcgacta
    19321 tgggaaatgg tatcggaatt acccgaagaa ttacaatcgg agctatctgc tctgctcact
    19381 catttttcaa gcattgaaga actaagcgaa catcaagagg atattatcat tcattccgat
    19441 tgtgatgata tgtatgacgt ggcacgctac tacattgaag aaacgggtgc tttaggcgaa
    19501 gtaccagcta gtcttcaaaa ctatattgat tatcaagcct atggtcggga tttagacctt
    19561 tcaggaacgt ttatctcaac caatcatggg atttttgaaa tcgtctatta aatctgtcgg
    19621 tacattacta ctggcagatt ttctatttta cggggtggct caatcagcta cccctatttt
    19681 ttatgaaagg attgattaca tgaagaaaat acgaagctat accagtatct ggtctgtgga
    19741 aaaggtactg tattctatca atgattttag acttccgttt cccataacct ttacgcaaat
    19801 gacatggttt gtcgtgtcac tctttgcagt gatgatactt ggcaacttgc cccctctttc
    19861 catgatagag ggagcatttc tcaaatactt tgggattcct gtggctttca catggtttat
    19921 gtctacaaaa acttttgatg gtaaaaagcc ttatggattt ttgaagtctg tcattgctta
    19981 tgcactgcga ccaaagctga cctatgcagg aaaaaaagta acgcttggca gaaaccagcc
    20041 acaagaagcc attacagcag ttaggagtga attttatggc atatccaatt aaatacattg
    20101 aaaacaatct cgtctggaat aaagacgggg aatgttatgc ttactatgag cttgttcctt
    20161 acaattactc atttctaagt ccagaacaga aaatacaagt gcatgattct ttcagacagc
    20221 ttatcgcaca aaatcgtgat ggcaaaattc atgctttaca aatcagtaca gaatccagca
    20281 tacgttctgc acaagagcgt tccaaaaatg aagtcactgg caagctcaaa gcggttgcct
    20341 atgacaaaat cgaccaacag acagacgctt taatatccat gattggcgaa aatcaagtga
    20401 actaccgttt ctttatcggc tttaagttgc ttctcaacga tcaggagttt tctatgaaaa
    20461 gtcttaccgt tgaagcaaaa aatgctttgt ctgattttgt ctatgatgtg aaccataagc
    20521 tgatgggcga ttttgttagt atgagtaatg atgaaatcct gcgttttcag aagatggaaa
    20581 agctcttaga aaataaaatc tctcgtcgtt tcaaaatccg caggttagat aaggacgact
    20641 tcggctatct gattgaacac ctttacggac agacaggcac tgcctatgaa gagtatgagt
    20701 accatctatc aaagaaaaag ctggataatg aaacgctgat taaatactat gacttgatta
    20761 agcctactcg ctgtttggtg gaagaaaaac agcgatattt gaaaatccag caggaagatg
    20821 aaaccgtcta tgtagcttac tttaccatta acagcattgt cggagaactg gacttcccgt
    20881 cctctgaaat cttctactac cagcaacagc aatttacatt cccgattgat acgtcaatga
    20941 atgtggaaat tgtagcgaat cgtaaagccc tatctactgt ccgcaataaa aagaaagaac
    21001 tgaaagactt ggataaccac gcttggcaaa gtgataatga aaccagctcc aatgtggcgg
    21061 aagctctgga aagtgtgaat gagctggaaa ccaatttaga ccaaagcaag gaatctatgt
    21121 acaagctgtc ttatgtggta agggtatcag caaatgatct tgacgaactc aaacgtcgtt
    21181 gtaatgaagt gaaagatttt tatgacgatt taagcgtaaa actggtacga ccatttgggg
    21241 atatgctcgg cttacatgaa gaatttttac ctgccagcaa gcgttatatg aatgattata
    21301 ttcaatacgt gacctctgat ttcctcgctg gtttaggttt tggtgctact caaatgctgg
    21361 gggaaaatga ggggatttat gttggctaca gcttagatac tggacgcaat gtctatctga
    21421 aacctgctct tgccagtcaa ggggttaagg gttcagtaac caatgcgtta gcgtcggctt
    21481 ttgttggttc gctgggtggt ggtaaatcct ttgcgaataa ccttatcgtc tattatgcgg
    21541 tgctttatgg ggcacaagca gtgattgtag acccaaaagc agaacgtggc agatggaaag
    21601 aaaccttgcc agagatttcc catgaaatca atatcgtcac tctgacttct gatgagaaaa
    21661 acaaaggctt acttgaccct tatgtgatta tgaaaaatcc caaagattct gaatcactgg
    21721 ctattgatat tctgacattc cttacgggga tttcctctcg tgatggggaa cgcttcccaa
    21781 tccttagaaa agccattcgt gcagtaacca atagtgaagt acgagggttg atgaaagtga
    21841 ttgaggaatt acgggttgag aatacgccac taagtaccag tatagccgac catatcgaaa
    21901 gttttacaga ctatgacttt gcacatttat tattcagtaa tggttatgtg gagcagtcta
    21961 tcagcttaga aaaacaactg aacattatac aggttgcgga cttggtactt cccgacaagg
    22021 aaacttcctt tgaggaatat accactatgg agcttttatc cgttgctatg ctgattgtca
    22081 ttagtacctt tgctttagac tttatccata cagaccgaag cattttcaag attgtagatt
    22141 tagacgaagc atggagcttt ttacaggtag cacaaggaaa aacactatct atgaagctgg
    22201 ttcgggctgg tcgtgctatg aacgctgggg tatatttcgt gacccaaaat acagacgacc
    22261 tcttagatga aaaactgaaa aataacctcg gcttaaaatt tgcatttcgt tccactgacc
    22321 ttaacgagat taaaaagacc ttagcctttt ttggtgtaga cccagaggac gaaaacaatc
    22381 agaagcgatt gcgtgatttg gaaaacgggc aatgccttat cagtgattta tatggtcgtg
    22441 tcggtgtgat acagttccac cctgtatttg aagaactgct ccatgccttt gataccagac
    22501 cacctgtgcg aaaagaggtg taaatgtgaa accatcaata gtaaacagaa taaaatcaaa
    22561 ctggacgctg aaacgtctag gtaaagtggc aatgacagtg gctttcacac ttgtgattgc
    22621 catttttctt ttagccatgc tgggaacggt ggttcaagct gcgggcttgg tagatgatac
    22681 ggtcaatgtg gcaaatgaat acagccgata cccacttgaa aactatcaac tggattttta
    22741 tgtggataat agctggggct ggcttccgtg gaactggtcg gacgggattg gaaaacaggt
    22801 catgtatgga ctatatgcca ttaccaattt tatttggaca atcagtttgt atgtttccaa
    22861 tgcgacaggt tacttagtac aggaagccta ttccttagac ttcatttccg ctacagcaga
    22921 ttccattggt aagaatatgc agaccttagc tggtgtgagt gcaaacggat tttcaacaga
    22981 gggtttctat gttggattcc tcttactctt gattttggtt cttggggttt atgttgccta
    23041 tacgggactg ataaagagag aaaccacaaa ggcaattcat gccattatga attttgtgct
    23101 ggtgtttatc ctatcggctt cctttattgc ctacgctccc gactacatta aaaaaatcaa
    23161 tgacttttca tcagacatca gtaatgccag tttatcactt ggcacgaaga ttgtcatgcc
    23221 ccattccgat agtcaaggca aggacagcgt ggacttaatc agagatagcc tgttttccat
    23281 acaggttcag caaccgtggc tactgcttca atacaacagt tcagacattg aaagtatcgg
    23341 tattgaccgt gtggaaagcc tgctctccac cagcccagat tccaacaatg gcgaagacag
    23401 agaaaaaatt gttgcggaag aaattgaaga cagaagcaat accaatctaa ccattacaaa
    23461 gaccattaac cgtttaggta cagtcttctt cctatttgtc ttcaatattg ggatttccat
    23521 atttgtattc ctattaacag gaatcatgat tttctcgcag gtacttttta tcatctatgc
    23581 tatgtttctg cctgtgagct ttattttaag catgattcca tcatttgatg gtatgtcaaa
    23641 acgagccata acaaagctct ttaataccat tttgacacga gctggaatca cattgattat
    23701 tacgacagca tttagtattt caaccatgct ctatacctta tcggctggtt atccgttctt
    23761 tttgattgct tttctacaga ttgtgacctt tgcaggaatc tacttcaagc tgggcgattt
    23821 aatgagtatg ttttctctac agagtaacga ttctcaaagt gtgggaagtc gtgtgatgag
    23881 aaaacctcgt atgcttatgc acgctcacat gcaccgtcta cagcggaaac ttggacgttc
    23941 catgactact ctaggggctg ggtctgccat tgttacaggt aaaaaaggac agtcgggttc
    24001 ggggagttct gcaaggacac aagcagatca ctcccgacca gacggaaagg aaaaatcaac
    24061 acttggaaaa cgtatcggtc aaaccatcgg tacagtagct gataccaaag acagaatggt
    24121 agacactgct agtggtttga aagaacaggt taaagatttg ccgaccaatg caagatatgc
    24181 agtatatcaa ggaaaatcca aagtaaaaga gaatgtccgt gatttaacca gtagtatttc
    24241 tcaaaccaaa gcggacagag ccagtggacg caaggaacag caggaacaaa ggcgaaaaac
    24301 cattgcgaag cgtcgctctg aaatggaaca ggtcaaacag aaaaaacagc ctgcttcttc
    24361 tgttcatgaa agaccgacta caagacaaga acaatatcat gatgaacaga cctcaaaaca
    24421 gtctaatatt cagacttcat ataaggaatc tcaacaagcc aaacaagagc gtccagcagt
    24481 taagtccgat ttttcaagtc caaaagtgga acgccaaggc aataccgttc aagaaaaaac
    24541 cgttcaaaag ccagcaactt caaccactac agcagataga acttcacaac gtccaatcac
    24601 aaaagaacgt ccgtctactg ttcaaagagt accactacaa aatacaagaa gtagaccacc
    24661 aatcaaaacc gccaccatta agaaagtcgg taagaaacca tgaagttgaa aactttagtg
    24721 attggtggtt ctggattatt cttgatggtc ttctcactgc ttctgtttgt tgccatttta
    24781 ttttcagatg aacaggacag cggaatttcc aatattcatt atggaggtgt gaatgtttcc
    24841 gcagaagtgc tggctcataa gcctatggta gaaaaatatg ccaaagaata tggcgttgaa
    24901 gaatatgtca acatacttct tgcgattata caggtggaat cgggcggtac tgcggaagat
    24961 gttatgcagt cctcggaatc cctcggtctt ccacctaatt cattgagtac agaagaatcc
    25021 attaagcaag gtgtgaagta tttcagtgaa ttattagcca gtagcgaaag gctcagtgta
    25081 gatttagaat cggttatcca gtcctacaat tatggtggtg gtttcttagg gtatgtggct
    25141 aatcgtggaa ataaatatac ctttgaactg gctcaaagtt tctcaaaaga gtattcaggt
    25201 ggcgaaaaag tgtcttaccc caatcccata gccataccta tcaatggggg ctggcgatac
    25261 aactatggca atatgtttta tgtgcaactg gtaacgcagt atcttgtcac aacagagttt
    25321 gatgatgata cggtacaagc catcatggac gaagcactga aatatgaggg ctggcgatac
    25381 gtttacggtg gagcttcccc gactacttct tttgattgta gcggactgac acaatggacg
    25441 tatggaaaag ctggaattaa cttaccacga accgcacaac agcaatatga tgtgacccag
    25501 catatcccac tatcggaagc acaagctggc gatttggttt tctttcattc tacctataac
    25561 gctggctctt atattactca tgttgggata taccttggca ataaccgtat gtttcatgca
    25621 ggcgacccaa tcggttatgc cgacttaaca agcccctact ggcaacagca tttagtggga
    25681 gcaggacgaa tcaaacaatg agaaaggaag atttaatgat gaaatttaga aaaaatcaga
    25741 ataaagaaaa acagatacca aaggaaaaga aacctcgtgt ctactataag gtcaatcctc
    25801 ataaaaaggt tgtgattgcc ttgtgggtac ttttagggct tagtttcagc tttgcgatat
    25861 tcaagcactt tacagctata gatactcata ctattcacga aacaactatc atagaaaagg
    25921 aatacgttga tactcatcat gtagaaaatt ttgtagagaa ctttgcgaaa gtctactatt
    25981 catgggagca atccgataag tccattgata atcgaatgga aagtctaaaa ggctatctga
    26041 cagatgaact tcaagctctc aatgttgata cagtacgcaa agatattcct gtatcgtctt
    26101 ctgtaagagg atttcagata tggacggtag agccaactgg cgacaatgag tttaatgtaa
    26161 cctacagtgt agaccagctc attacagagg gagaaaatac aaagaccgtc cactctgctt
    26221 atatagtgag tgtctatgta gatggttctg gaaatatggt actggttaag aatccgacca
    26281 ttaccaacat acctaagaaa tcaagttata aaccaaaagc cattgaaagt gaggggacgg
    26341 ttgattccat tacaaccaat gaaatcaatg agtttttaac gacgttcttc aagctctatc
    26401 ctacagcgac agccagtgaa ctttcctact atgtgaatga cgggatatta aaaccaatcg
    26461 gaaaagagta catctttcaa gaactggtaa atcctattca caatcgtaag gataatcaag
    26521 tcacggtatc gctgacagtg gagtatatcg accagcagac caaagcaacg caggtatctc
    26581 aatttgattt ggtacttgaa aagaacggga gtaattggaa gattatagaa taacaaatat
    26641 tggtacatta ttacagctat tttgtaatca cgtactctct ttgataaaaa attggagatt
    26701 cctttacaaa tatgctctta tgtgctatta tttaagtatc tatttaaaag gagttaataa
    26761 atatgcggca aggtattctt aaataaactg tcaatttgat agtggaaaca aataattgga
    26821 tgtccttttt taggagggct tagttttttg tacccagttt aagaatacct ttatcatgtg
    26881 attctaaagt atccggagaa tatctgtatg ctttgtatgc ctatggttat gcataaaaat
    26941 cccagtgata agagtattta tcactgggat ttttatgccc ttttgggctt ttgaatggag
    27001 gaaaatcaca tgaaaattat taatattgga gttttagctc atgttgatgc gggaaaaact
    27061 accttaacag aaagcttatt atataacagt ggagcgatta cagaattagg aagcgtggac
    27121 agaggtacaa cgaaaacgga taatacgctt ttagaacgtc agagaggaat tacaattcag
    27181 acggcgataa cctcttttca gtggaaaaat actaagataa acatcataga cacgccagga
    27241 catatggatt ttttagcaga agtatatcgt tcattatcag tattagatgg ggcaattcta
    27301 ctgatttctg caaaagatgg cgtacaagca caaactcgta tattgtttca tgcacttagg
    27361 aaaataggta ttcccacaat cttttttatc aataagattg accaaaatgg aattgattta
    27421 tcaacggttt atcaggatat taaagagaaa ctttctgcgg aaattgtaat caaacagaag
    27481 gtagaactgc atcctaatat gcgtgtaatg aactttaccg aatctgaaca atgggatatg
    27541 gtaatagaag gaaatgatta ccttttggag aaatatacgt ctgggaaatt attggaagca
    27601 ttagaactcg aacaagagga aagcataaga tttcataatt gttccctgtt ccctgtttat
    27661 cacggaagtg caaaaaacaa tatagggatt gataacctta tagaagtgat tacgaataaa
    27721 ttttattcat caacacatcg aggtcagtct gaactttgcg gaaaagtttt caaaattgag
    27781 tattcggaaa aaagacagcg tcttgcatat atacgtcttt atagtggcgt actgcatttg
    27841 cgagattcgg ttagaatatc ggaaaaggaa aaaataaaaa ttacagaaat gtatacttca
    27901 ataaatggtg aattatgtaa aatcgataag gcttattccg gggaaattgt tattttgcag
    27961 aatgagtttt tgaagttaaa tagtgttctt ggagatacaa agctattgcc acagagagag
    28021 agaattgaaa atcccctccc tctgctgcaa acgactgttg aaccgagcaa acctcaacaa
    28081 agggaaatgt tacttgatgc acttttagaa atctccgaca gtgacccgct tctgcgatat
    28141 tatgtggatt ctgcgacaca tgaaatcata ctttctttct tagggaaagt acaaatggaa
    28201 gtgacttgtg ctctgctgca agaaaagtat catgtggaga tagaaataaa agagcctaca
    28261 gtcatttata tggaaagacc gttaaaaaaa gcagagtata ccattcacat cgaagttcca
    28321 ccgaatcctt tctgggcttc cattggtcta tctgtagcac cgcttccatt agggagcgga
    28381 gtacagtatg agagctcggt ttctcttgga tacttaaatc aatcgtttca aaatgcagtt
    28441 atggagggga tacgctatgg ctgtgaacaa ggattgtatg gttggaatgt gacggactgt
    28501 aaaatctgtt ttaagtatgg cttatactat agccctgtta gtaccccagc agattttcgg
    28561 atgcttgctc ctattgtatt ggaacaagtc ttaaaaaaag ctggaacaga attgttagag
    28621 ccatatctta gttttaaaat ttatgcgcca caggaatatc tttcacgagc atacaacgat
    28681 gctcctaaat attgtgcgaa catcgtagac actcaattga aaaataatga ggtcattctt
    28741 agtggagaaa tccctgctcg gtgtattcaa gaatatcgta gtgatttaac tttctttaca
    28801 aatggacgta gtgtttgttt aacagagtta aaagggtacc atgttactac cggtgaacct
    28861 gtttgccagc cccgtcgtcc aaatagtcgg atagataaag tacgatatat gttcaataaa
    28921 ataacttagt gtattttatg ttgttatata aatatggttt cttgttaaat aagatgaaat
    28981 attttttaat aaagatttga attaaagtgt aaaggaggag atagttatta taaactacaa
    29041 gtggatattg tgtcctgtat gtggaaataa aacacgatta aagataaggg aagatactga
    29101 attaaaaaaa ttccccctct attgtccgaa atgcagacaa gaaaatttaa ttgaaataaa
    29161 gcagttcaaa gtaactgtga ttacagagcc agacgcaaag acgcagagcc gataaaatga
    29221 gattaataca atctcatttt atcggctctt tccgttatgt atggattctt ttaattagtc
    29281 ttcgatgttt cttgcttcgt tgataccgct ggctaaagat tccattaagg atagttcttt
    29341 gtctgtaaag ctatccatgt atttctctat ctgtaatcgt cgggtgcttt ttaccaagtt
    29401 attagcaggt aagaaaaatt catcaacgga aacatgaagt aacgatacaa ggtcataaag
    29461 aacttgtatg ctggggtgtt gccctttatt ttcaatatta gttaagtacc gtgggtcaat
    29521 ttcaatcaat gctcccactt gttcacgagt taaacctcgt ttcaatcgag cttctttaat
    29581 ggctaaacca aaggctctaa aatcatattt atcttctttt ttacgcatag tagaccacct
    29641 ctatacattt tattgttcct actgaattaa aaacaggtat agaaaaacgt gttatatggt
    29701 ttataggttt atatttaata aaaagcacta ctaaacgcca ataaaaaaaa ccgttatatg
    29761 gtagtgctat ttacgctgtt aaaatattgt atattacttc caaatggcgg tttgttggag
    29821 gtcaacgtcg ccatgaagta catcatatac aataaatttc cttacattgg gttcttgtca
    29881 aaaaaagtcg tctatctgca atagataagt acgtccacca atgtggtttt ataaatcata
    29941 tagatagaat aacagaagca tgtaaacaga gaaataaatc tgtttatatg cttttttggc
    30001 tattcagaac ttttttacaa agtttattta tcagtaatgc aacaaatccc cctttcacat
    30061 tgggactaag agtgaaagga gataaacgag caaggctcac ttcctttcct agacagaaag
    30121 ggggtgagaa acatgaaacc atcttctttt cagaccacaa tagaaaatca gtttgactat
    30181 atctgtaaac gtgctatgga agacgagcga aagaattata tgctttatct ttcaaggatt
    30241 gcaaagcgtg aggtgtcctt ttcggatgtt ggcgattatc ttgttagcca gtttgcgaca
    30301 acagataact attcaactga ctttcagatt tttacactca atgggttatc agtaggcgtt
    30361 gaaaatgatt tgttgagtga agcattacgt gagttgccag acaagaaacg tgaaattcta
    30421 ctgctgtttt actttatgga catgagcgat tcagaaattg cagacctgtt gaaattgaac
    30481 cgttctactg tctatcggca tagaaccagt ggactagcct taattaaaaa gtttatggag
    30541 gaatttgaag aatgaaaaca caatatccta tgattccctt tcctctcatt gtaaaggcaa
    30601 cagatggcga taccgaagcg attaaccaga ttctacatca ttacagaggg tacataacga
    30661 agcgttccct acgacttatg aaagatgaat atggcaatca aagtatggtc gttgatgaag
    30721 tcttacgtgg aagaatggaa accagactga ttacaaagat tttgtcattt gaaattaagt
    30781 aatatcctct ctcctttcgt ggaagcgtgc taaaccattc cacgcttccc gaacagggag
    30841 gtttgttatt ccaccaaagc atattgagct ttcaatgtgt tttgataggc taacgagcca
    30901 ttgttctttg aaaactgaat aaaagtaatc gaatacgttt cgataagaaa agagccaacg
    30961 gaactaaccg ccatgaccta tcttataaag atagcgagcg attcatgtta gtgatccgag
    31021 aagcaatctt tagcaggatt gcctgcaacg acattcttat cgtgataatg atactcccat
    31081 acagtcaata gtccgagcgt gataaaaccg tcgcaggcaa tgagtatggc tacatgagaa
    31141 ccatgcaggg gtggaactcc cgtgagcttt gctaaagctg ttcgattgct ggtaaaacaa
    31201 cttttatgaa atccaaataa gtgatttgga aaggaggatt ttatgaagca gactgacatt
    31261 cctatttggg aacgttatac cctaaccatt gaagaagcgt caaaatattt tcgtattggc
    31321 gaaaacaagc tacgacgctt ggcagaggaa aataaaaatg caaattggct gattatgaat
    31381 ggcaatcgta ttcagattaa acgaaaacaa tttgaaaaaa ttatagatac attggacgca
    31441 atctagcgtc gccaaagggt cttgtatatg ataaaatagt attaagtcgt atcaaggctc
    31501 tttccataaa ggaaaggagc aaatgccatg tcagaaaaaa gacgtgacaa taaaggtcga
    31561 atcttaaaga ctggagagag ccaacgaaaa gacggaagat acttatacaa atatatagat
    31621 tcatttggag aaccgcaatt tgtttactcg tggaaacttg tggctacaga ccgagtacca
    31681 gcaggaaagc gtgattgtat ctcacttaga gagaaaatcg cagagttaca gaaagacatt
    31741 catgatggta ttgatgttgt aggaaagaaa atgacactct gccagcttta cgcaaaacag
    31801 aacgctcaaa gaccaaaggt tagaaaaaac actgaaactg gacgcaaata tcttatggat
    31861 attttgaaga aagacaagtt aggtgtaaga agtattgaca gtattaagcc atcagacgct
    31921 aaagaatggg ctattagaat gagtgaaaat ggttatgctt atcaaaccat caataactac
    31981 aaacgttctt taaaggcttc attctatatt gctatacaag atgattgtgt tcggaagaat
    32041 ccatttgact ttcaactgaa agcagttctt gatgatgata ctgtccctaa gaccgtacta
    32101 acagaagaac aggaagaaaa actgttagcc tttgcaaaag ctgataaaac ctacagcaaa
    32161 aattatgatg aaattctgat actcttaaaa acaggtcttc gtatttcaga gtttggtggt
    32221 ttgacacttc cagatttaga ttttgagaat cgtcttgtca atatagacca tcagctattg
    32281 agagatactg aaattgggta ctacattgaa acaccaaaga ccaaaagtgg cgaacgtcaa
    32341 gttcctatgg ttgaagaagc ctatcaagca tttaagcgag tgttagcgaa tcgaaagaat
    32401 gataagcgtg ttgagattga tggatatagt gatttcctct ttcttaatag aaagaactat
    32461 ccaaaagtgg caagtgatta caacggcatg atgaaaggtc ttgttaagaa atacaataag
    32521 tataacgagg ataaattgcc acacatcact ccacatagtt tgcgacatac attctgtacc
    32581 aactatgcaa atgcaggaat gaatccaaag gcattacagt acattatggg acatgctaat
    32641 atagccatga cgctgaacta ttacgcacat gcaacattcg attctgcaat ggcagaaatg
    32701 aaacgcttga ataaagagaa gcaacaggag cgtcttgttg cttagtagta caaatgaatt
    32761 tactacttat ttaccacttc tgacagctaa gacatgagga aatatgcaaa gaaacgtgaa
    32821 gtatcttcct acagtaaaaa tactcgaaag cacatagaat aaggctttac gagcatttaa
    32881 gaaaatataa aaagataatt agaaatttat actttgtttt tattaaaaag cagcaaacta
    32941 taaactagta ggttccacac taaatgtagc cccatactgc cccacaagtc cgatttatag
    33001 cgtaccatcc ctaaaaacat tcccaatgaa acatataaac accaagctag aatggttcct
    33061 ggatgatgag ctaaggcaaa taaaacactt gtcaaagcaa ctcgaatatc taattttcta
    33121 accaagttcc ataaaatttc tctatacaaa aattcttcaa ccatactcgc attgattaag
    33181 aacaataaaa atgaaaacca aggaacttga tgttgaagcc caattaagtt tgcttgattt
    33241 gtgctttctt gagcatgaat cagactaaaa tatagactga taatcagtag gctaacgaat
    33301 ccaataccaa tccactttat cctagtttcc atattgacct tggccacttg ttttcgttga
    33361 ccatacatcc ataaaaaaga aatgagcgac gctccataga taatctgtag tatagttaac
    33421 tcaccgatac aaagaaattt cagtaagtat aaggatacca ataggacatt tacttgttgg
    33481 aatatataaa ctggaattat tcttttcata gttacctccg aaataaatct tcataatcta
    33541 aatctaatac ctgcacaatc ctctctaccc atggactttg aggcattcgt tgttccatct
    33601 tatagtggcg aatcttttga tacaaacgat tcaattcact tggatagtga aactctcccg
    33661 caaacatttt tctggttaac tcaatccagc tgatatttct ttcagccaaa ataatggaca
    33721 agttctccca aaatcgttca gccatattgc ttctccttta gttagataaa taatgtgttt
    33781 gtgccatgta aatcaattgt ttcgtatctc ttggtaataa agccctagct tcctccaaat
    33841 ttagatttgg ataaactcgc ttatttgaaa ccgcaagagg aagtctgatg gttagttcag
    33901 gattttttaa tatcatttca atgaaatccg ttagtcttaa attgtcacgg ttcttaaatc
    33961 gtaataaatt aggagataaa aactcaaaac aatctgaaga atagctcatc atctcaatta
    34021 atttatccct tgtcatttca gaaatcgaat gacaggatac ctcaatgcca tagttttgga
    34081 agaattctaa aagaagttga tttctatggt tatttttact tagatagaga tcaatcatgt
    34141 gagacctccc aaagattcgg ttccatttga tattctgaga cgattaagga atctaataaa
    34201 ttggagaagt taattgattt cttgtcttca tcataagctt ttacagttac ttgggttgta
    34261 agtattccct cttttccctc ggctcgatag ccttgcccat ataaaacaaa aacaagatta
    34321 tgattatcat ctataaaggc atcagctccg ttctttatat cctgactttc aaggaattcc
    34381 ataatgtttt gaagatagga ttcgtaaaat agggggtaat tgtgtttttt atggtaataa
    34441 tctaaaaatg tcacctcaaa ctcacatgga taattgggca tcaaaaatat ttgttcatcc
    34501 aactgcatca tttctgcatc atgtaattct gtttctaatt catcacaata tagtattgac
    34561 tctttattta gcgctttcat ctttttcctc tatttctttt aatttttttg cgattgcggc
    34621 aatcacagga acagttacac tattaccagc ttgtttatag agctgactat tactagagac
    34681 ttttctagca gcttcaaaag cccaatcagg aaagccctgc agtcgaaaac actctttagg
    34741 agtgattcgt cgtattctca aacggtaaaa ttgtccatct attaaaacac cagctacatg
    34801 gtaaacttgt ttatcttctc cttcatagct agccactact actcccattt gaccactagt
    34861 tgttaatgta ttcgctatac cttttccaac tctaccacga cgatactgag aacttggtct
    34921 ttctaaattg attgaatctc caatctctgc ttgagcatac ccttttttag ttgcttcccg
    34981 gacttttaga aattggattg gttctggaat cagtattttg ggaattttat ctcctccttg
    35041 catcgtagtc agtgttggag ataagccctc gcttccatag actcgacctg tctccttaaa
    35101 gctagtcggt aaatctccaa caacgacaat accatgacga tcctgagtat ttaaagtaaa
    35161 catcggctct tggttttcct taaagcgtct cccattttgt ctcttgtcta atctgtctgg
    35221 tgtcatacaa ggaatcgcaa ccttgaatcc ttctcctttt ccacgaacta aggttggtgc
    35281 aagaccttct gaataataga ctttaccgct cattccactt tttgatggat tcaaattccc
    35341 tagtgttttt aaagtctcag agttagttgt ttgaccttct cgtctgaaag gaaataagag
    35401 tctggtacct ctctttctag aatgtccgat aataaacacc ctctctctgt tttggggaac
    35461 gccaaaatcc ttactgttaa gcaactgcca ctcaacatca aaccccaact catcaagtgt
    35521 ggtaaggatt gtggtgaacg tccgtccctt atcgtgattg agtaggcctt taacattttc
    35581 aagaaaaaga aaacgtggtt ggatttgttt ggccgcccga gcaatttcaa agaacaaagt
    35641 tcctctagta tcttcaaatc ccaatcgtct tcctgcgatt gaaaatgctt gacaagggaa
    35701 tcccccacag atgatatcga ctttccctct aagtttttta aattctgcat ctgaaacatc
    35761 tcgtatgtca tgaaattcta tttctccttc cgtttgaaaa atggacttat aagatttcct
    35821 agcaaattta tcaatctcac aaaatccaat acactcgtgt ccaacacttt ccattccaag
    35881 tcgaaatcca cctatacctg aaaataaatc aataaatctc atttcttgat cacctctttc
    35941 ttatcgacta ccattgtcat aactgtcact ccacttgaaa tgacaataag cataactaat
    36001 atccactcga ttgacgacat ttaaccacct ccttttctaa cacggttatt ccaaacagaa
    36061 tacaggccat taaacacaaa ttcagcaagt acttccgctc gtctaacaaa gcgaacattg
    36121 tcaagagcat actgatagat tctttcaaaa tcagtcatag caatttcact ggctgtttca
    36181 gaaaaacctt ctcgtctaaa ttgatcttgt accaatcccc aaatataatc tcgatcatat
    36241 tttgtgacct tttctacttt tcttttcaaa ataggttgag tattcctatc ctcctcatcc
    36301 tcaataaata aagaatcagt ctcactatat ttagtctcac taacttcagt ctctctaggg
    36361 gctgaatgtg agactggggc cgtttcattt tcaacctgcc ctagtctttt tttaacacta
    36421 ggcctgtttg aattacctac tggggtagaa gataattccc ctaaataaat cttattagct
    36481 agtcttcctt tctcacttga agactgttga acttcatcaa ttaagtcata ttctttaaga
    36541 atttttttga tagacagtaa ttttgacttc gagcaaccta acagcttcat cagtttagaa
    36601 ttagaaaata ctaaataaac cgctccttct tcatctatcc aaccacgact gagagataat
    36661 tctaaacgat cttttaaaat agaataagcc acctttactt ctagtttcat atccatatat
    36721 ttctcatcct caaaaagaat tttaggtaat ttgtaatacc gttctgaagt ttggtattga
    36781 tttgcggtaa ttcgtttcat agcgcacctc caagttcttt gagtgttaaa tctccgcttg
    36841 attccaatcg aaccaagcca cttttttcta attcagccat aagagagatg gcttcaacaa
    36901 tatctattcc catttcacgt actaaaaatg aaatgacaat atagcgtgat gattgtaatt
    36961 cttttgtcat tttccctcct gaaaataaaa aaaggagaac aaaatacaat tgttctctct
    37021 ttagataaat atttattgtt gtattcattt ttccaatgcg caaacgacat ctacaaatac
    37081 atatacatct atgtgccttt ttaggacttt tttgacgtca aaattgcctt tatctacaaa
    37141 cacaaaatgc ttgtaaaata gcttaaaatc aaggattttc accctttttt tcgttgtagc
    37201 aacactacac actccacgtg atgcgtttga ggaaatagat ccaccggctg gactttcttc
    37261 aattcatatc ccaactcttg gtatagttta atatcacgcg ccatggttgc gacattgcag
    37321 gagatatagg cgatgcgatc ggctcctgtt tgggcgcttg ctttgataaa gctttctgtc
    37381 aagcccttgc gtggaggatc aaccaagata acggttggtt gaatcccatc tttaagccaa
    37441 ttcttcatag cattttcagc tgtgtcacag acatagtggg cgtttgaaat attgttcagc
    37501 tgagcatttt ttttactatt ctcaaccgct tctggaatca gttcaacacc gtagacttct
    37561 ttgacatgct tggcgactga taaaccaatg gttccaatac cagaataagc atcaataacc
    37621 acgtcatctt tttttaactc tgcaaagtca atggctgttt gatagagttt ctccgccatt
    37681 tcagtattga cttggtaaaa ggctgggcca gcgatttgga agtcatttcc caacatctgg
    37741 tccgtaatat agtcttgacc ataaagagtg cgccactcct taccaaaaat cgcattggta
    37801 ttctggtcgt tgatattttg catgacagac acaatctctg ggaactgctt gataacttgt
    37861 tcaatcaatt ggtcaacacg aaaaactttt ggacgagttg tcaccaaaac gaccatgatt
    37921 tgccctgaat agtgaccacg acgcaccaca agattccgaa tcaatccaga atgttccttt
    37981 tcgtcataag gttttaaatc aaaacgacgg aacaggtctc gaagagctac tacgacttgg
    38041 tcaatgacag gatcctggat aaagaaatct tcaaggggca tgaggttgtg cgaattctta
    38101 cggaaaaatc ctgtttccaa gacaccattc actcgacgaa cgggcacctg cgccttattg
    38161 cgatacttga ctggatgttc cataccaagc gtttcagcaa cttctacatc tgcaattcca
    38221 gcaatcttgt agagactgtc cttgacttgc ttggttttaa acttgagctg ttctggataa
    38281 gaaaggtgtc ctaaatccgc gattcctgaa cgcaggtaag ccaaatctag atcttgatta
    38341 cggtgtggtg actggacaag gtatttttca acttttccaa agccaatctt tttattgacc
    38401 ttgaggacac gcatgagaat tttttcactc ggtaaagcat tctctacaaa aaagaccaaa
    38461 ccatctacct tggcaactcc tgccccttca tgggtcaaat caacaatttc aacttctaca
    38521 atatcatttt tctttaacat tcttttctct ttctattggc cgacaaaaaa gacggcaacg
    38581 ttacggttac catccattat accatgaaat ttcttaagaa ccaaaactct tgaagaagtt
    38641 gacaagggct tgccagaggg agcttaagaa gttaccaccg tcctctagcg ccttatccgc
    38701 atcaaagtta aggttgatat ttttaaaact gtcgccagct tgtgatacga tgctttgttt
    38761 aaggtcattt agggttttag tgaaatctgc attgctgagg atatcactct ttgagagatt
    38821 caaggcaaaa ttgatgatga tattgatctg gtttcctgtt atgacctgat caagtttgta
    38881 attttttaag gtatcttcaa caatcttgcg tacatcttct tctgtcagat ttcccttgct
    38941 ttctttagct ttggcgagtc ctgacttgat atcagctagg gcaacgttta atttattagc
    39001 atcatagcct gatttgtcct tgttttcagc attgatatct gacaaagcct ttagctcttc
    39061 ttgagccaaa tctttattgg cttgcggcac cttggctcca ttagcttcta gcgaatagta
    39121 gatcccagcc aaagcactct cacctgtaac tggaataggg gctgctacag tgattttggc
    39181 atgttccata cccagcgtta ctgctgcgtt tcggtacata tcctgagtca ccttagtgat
    39241 attttctggt gtttcaatct tgacctcaag tggcgatttg tcacctagct tttgaatctt
    39301 ggctgatgaa tacaactgta agctagagtc attggccaca ttcatgattt tagaataaac
    39361 atcaggtgtc atggtcttga gttctttggt atctgttgag gcattgtagc ccagtttttt
    39421 aagagtttga tttttttggt cttcagatag ggaggaacct aggacatatt caggttggac
    39481 ataggtttca tcgataactt tttgaacatc tgttgctgca tgggcgctat tcatagctgt
    39541 tactgcccac aagaccgcag caccggtcag aaagagtttc tttctcatag ggaatttcct
    39601 cctttacttt tctagagtaa tatatctatc ttaaagaaaa cttataacaa aaacacctgg
    39661 tctagccaga tgttgaaaag agagtgaaac atttgatgat gtaaaggtta agtcgtacct
    39721 gtctagaata ataatagttt cctccattta catagagttc agcaccgtga aaaatggaaa
    39781 tggggtgaat ataactataa gtctttccag tcctattacc aagcaagggg gcaacagtct
    39841 cacgagagta ctgtttggct agagccaagg tattttcctt gccattttgg gcgataaaat
    39901 cgatataggc aggtccaaaa ttataggctt gaacagctgt ccagatatct acacccttct
    39961 tctgcgccag atagagattg cctgtcagag tttgaatgcc ttgccgaatg ctagaggcat
    40021 tatcattgat ggtgttggtg gaaccacttg cagactcact agactgcata acatcgcctt
    40081 cttttccttt tgtttcagta taaatcatag caagcacaag ctcttcgttt gctggggtgt
    40141 ctttttcact caatatttct cgcaccatgg gttgataggt catgacttgt ttgacatctt
    40201 gatgaacgcg gtaagcttta tagccagcaa aaaggaagac tgctagtaca agcactcttc
    40261 gaattcgttt aaacattatt tactttggat atcctcgata tttttgatta agatagagta
    40321 ggttccattt tcgttttgga taaactcaac agactcggcg tcttgataga cgttattggg
    40381 aacgatgagc tcaattccat ttgataagga gagtttttgg ttttcaaatt tctttaattg
    40441 gcgactggca tcaatttcat caaattgaac aggttctggt acggcttctt tgacttggtc
    40501 aataaagctc aaacgagccg tcagattgtt gtcaaaaagg tcattagcca atttctcagg
    40561 tgacaattca ttgctttctt ctaggttgtt gaaaatagct gatttgacct tggattgaaa
    40621 ttgaaaatca tctgtgttaa aagattcagc aattctctgg gctgtttttt ccagttcctt
    40681 gatagatttt ttaggagaaa tcttaggagc gacagcaaga agattatctg aaaaatagtt
    40741 caaaaaagtc ccgttgtact tgattcgttt ttcaatcagg tgatacttgc gactctgaag
    40801 attgaccacc aaggcctcgt cagcacccgt tccaaatcca ggcaggttat tctgagtcag
    40861 cttgattgga ttatcaactt ctcctccgag gtgggtcaag gtctcccgca gggcaattcg
    40921 caagaaagcg aaatgttcta caccttcttt agaaaattga acaaaaatca agtcattggt
    40981 cttgagattt tcagaaatgc taaactcctc tttccagaga ttagccagcg ttactgatgt
    41041 ctccaacaaa tcgtctgtaa tatgattgaa gaagggattt tcttcttcga aaatcccagt
    41101 cttggcttca tctgaataca catgttcaat ttttttacgt aggtattctt cgatttttgg
    41161 agtaatattg agaaacttat ctgctaagaa cagctcggta tcatccggac tgaactggtg
    41221 aataatggct ttcttaatat aaatatccat aaaagtttta gtcctcgtat aatgggaagg
    41281 catctgtcaa ttctttgact gcacttctca cttcttctaa tacagcctca ttttctgaat
    41341 tcttaagggt tttaatgatg agttcagcca ctttgcgact ttcttcttca ccaaatccac
    41401 gtgcagtaat agctgctgct ccgatacgaa tcccacttgt cttgaatggc gacaaggttt
    41461 cgtaagggat tgaattttta tttagggtaa tattgacttc atccagcaag ttttgagcaa
    41521 cttttccgtt ttctacaacc ttagtcacat caacaaggaa gagatggttt tcagttccac
    41581 ctgaaataat acggaaatca gggtcttgca agaagacatc tgccatagcc ttgctgttct
    41641 taattacatt ggcagcatat tccttgaagg ctggatccaa aacttctttg aaggaaactg
    41701 ccttagccgc cacaacatgc tctaaaggac cgccctgaat acctgggaaa atagctgaat
    41761 tgattttttt agcaagttct tcgtcattgg tcaaaatcaa accaccacga ggtccacgaa
    41821 gggttttgtg ggtcgttgtt gttgtgatat gagcgtatgg aactgggctt ggatgaaggc
    41881 cagccgcaac caaaccagcg atatgggcca tgtccaccat gagcttcgca ccgacagcat
    41941 ctgcgatttc acggaatttt gaaaaatcga taatttgaga atatgctgaa gcaccagcta
    42001 caatcagttt tggttttact tcttgggctt gtttcaagat agcatcaaag tctaagagtt
    42061 ccgtttcagg atcaacacta taagaaacaa agttgtaggt ttgaccagag aagctaacag
    42121 gagccccatg agtcaaatga ccacctgatg ccaaatccat tcccataacc gtatcacctg
    42181 gctcaatcaa ggacatgtaa gccgcacagt tagcttggct tcctgaatgt ggttggacat
    42241 tggcaaattt agcaccgaaa atttcttttg cgcgttcaat agcaagagtc tctacaacgt
    42301 ctactacatc agttccacca taataacggc gtcctgggta accctcggca tatttatttg
    42361 tcaagataga cccttgagct gccataacag ccttggaaac tacgttttcc gaagcaatta
    42421 actcgatatt attttgttgg cgttcttctt ctttggcaat agcattccag agatcagcat
    42481 catatgcttt aaaatcatct ttgtcaaaaa tcataggtct tctcctttat tgtgtgacta
    42541 gtccattagt ttgattttac aataagaaaa tcaaactaaa agatgcgaat aaaccgtttc
    42601 tgcattttat cacaagtata gccaactttt tcataaaatg catgagcacc cagacgatga
    42661 ttggcagaat ttaagcggat aaacccataa ccacatcttt ttgcttcttc ttccaaccct
    42721 tgtagtaaac ttttaccaat accttgacct tgcgcttgag gtgaaactgc taaagctaag
    42781 atattaaatc ctgctttgga atagagtgat tcgtaaactt cagcgtggac atatccaagt
    42841 aagacatgat tagctgcatc ctcatagcca agtaggaaat gatgggaatc ctgagacagt
    42901 ctagctagtt ggctagccgt ttcctctgga ctaaaagtat aacccaaagc ctcttggttg
    42961 atgtcacata tcgctttcac atctgtttct tgcaaatctc ttagcatttc aagcctcctc
    43021 aaaagaaatc tctggcaacc gagcaagaat atcttctcgt ttaattgcgc cttggcgtaa
    43081 gattttcacc ttgtctccag acaaatccac aatagttgaa tcctgtccag ttagaaaagc
    43141 atcgtcttcc agacccagaa cctcttggtc aaaatccttc agaatttgtt caaaggttac
    43201 accacttgcc tgacctgaga tattggcaga cggcccaatc aagggacctg tctctcgaat
    43261 taaatccagt gtgatagggt gactgggcat ccgaaatcca atagttgcaa ggtcagaatt
    43321 tacccaatag ggaactcggt cattggcttc gagaataatg gtcaagggac ctggcaaaaa
    43381 ggtctctaca agtttttgta gataagttgg ctgattctta gaaaagtgca agatatcctc
    43441 gaaagaggcg atattgagat tgagtgcctt atctctagga cgacgtttga gttggtaaac
    43501 atggtcaact gctttttcat ctaaggcctt ggcaaaaaga ccataaacag tctctgtagg
    43561 tagaacgaca gctccaccat tttccaactc ttgtctaatc ctgtccatca tcaaccacaa
    43621 ccatcctatt ttgaccaaat tggtctttga gtgttcgaac ttttttttca ggaagatgtt
    43681 ttctaaaaag ttcgggaaca ctttgacctt gcttgtatcc aatttcaagg taaatcttac
    43741 caccatcctt gagatagtct tttgcatctt ccgcaattct acagtaaata gctaggccat
    43801 cctcgtctgc aaagagagct agatgaggct ccgaatgcaa aacattcaaa cctacctctg
    43861 actcatcttc acgagagata tagggtggat tggatacaat tatatcatat ttttcagaaa
    43921 tttctgcaaa acaatcagat tttttaaaaa atatattaag attttgatcg ctagcattct
    43981 ctgatgcaag ctctaaggcc tcttgagaaa catctgctgc tgtcactgac caatctggtc
    44041 tattttttgc tagagcgaga gcaatagctc cactacctgt tccaatatcc agaactgaga
    44101 gattcgtctc aagattttca gttagaataa gctccactaa ctcctctgtt tctggacgag
    44161 gaatcaaaac ccgttcatcc acctttaaat gcattccata aaaatctgcc tgtccaatga
    44221 tgtactgagc tggcttgtga gctgctagtt gctggtaaat atcttctaca aattgttttt
    44281 cttcctctgt tgtcacctcc tgctggaggg caaaaataaa gtctgtaaaa gatagatttt
    44341 tcagactacg atagacaaaa gagaggcttt ccgcttcctc tccttgtctt atcaactctt
    44401 cttcaaaatt tgaaaataat tgagctaatt tcattatttg tttaattctt ctagtttttg
    44461 tgtttggtca taaagcacca aggcatccac aacttcgtcc aatttaccag acaaaatcgt
    44521 atctagtttt tggagggtca agccgatacg gtggtctgtg acacggtttt gtgggaagtt
    44581 ataagttcgg atccgttctg aacggtcacc agtaccgatt gtcgacttac gctcagcgtc
    44641 ttgttcatcc tgagcaatct gagcaaagtg gtcagcgacg cgtgcacgga taatcttcat
    44701 agccttctcg cggttcttct gctgggtacg ttcttcctgc atctcaacct tgatattggt
    44761 tggcaagtga acgatacgaa cggcagtcgc aaccttattg acgttctgtc caccagcacc
    44821 agaggcgtga tagatgtcga cacgaaggtc ttttggatca atgtcgtatt caacctcttc
    44881 aacttctggc ataacaagaa ctgtcgctgt cgaagtatga acacggcctt ggctttctgt
    44941 cacaggaaca cgttgcacac ggtgggcacc tgattcatac ttaagcttag agtatacaga
    45001 ctgacctgaa accatagcaa ccacttcttt aaaaccaccg acaccattca tagaggcttc
    45061 catgacttca aagcgccaac cttgggcttc cgcatacttt tggtacatag ttagcaaatc
    45121 tccagcgaaa agtgccgctt cgtctccacc agctgctcca cggatttcaa ggatgatatt
    45181 cttgtcatcg tttggatcct ttggaaggag caaaattttc agtttttctt catattcttc
    45241 tttttcagcc ttggcatctt tgagttcttg cttggccatt tcttccaagt ccgcatctcc
    45301 gcctgattcc ttaatcatct cttcggcatc gacgatattt tgaaggactt gtttatactc
    45361 acggtaggct attacggtgt cacgattgga agcttcttct tttgaaagct ccataaaacg
    45421 cttggtgtct gaaacgacat cagggtcact cagcaattct cctagttctt cataacggtc
    45481 ttctacagct tgtagttgat catagatgtt catttttctt cattctcctt attgatttca
    45541 ggggcaaaat aatgtttacg gcaaaccgag atataggttt cattaccacc aatctggatc
    45601 tgttctccat cgtaaacggg cagtccatcc tgtgttcgca acaccatggt cgcctttttc
    45661 ttgcaatact gacagatggt cttgatttcg tcaatcttgt ctgctaaaag caagagatat
    45721 ttggaacctt cgaacaattc attgcgaaag tcatttttca agccaaaagc catgacgggt
    45781 atgtctaact cgtccacaac acgagctagg tcataaacat ggtggcgttt gagaaactgg
    45841 gcttcatcga ccaaaacaca gtaaggtttt tctggtaggt ctcggatata gccaaagata
    45901 tccgttgttt cctcaatcgc aagggcaggg cgtttcatgc caattcgact cgacacatag
    45961 ccaacaccgt cacgcgtatc cagagccgag gtcataatca caacaccttt tccttgctcc
    46021 tcgtagttat aggccacttt gagaatctca atcgttttac cagagttcat ggtcccataa
    46081 cgatagtaca actgtgccat gtttcttgct tcacgtccat ttctaaattt ttgctacatt
    46141 ctagtatatc ataattttct taagctttaa acggcaaaat gtggtaaaat ggaagaaatc
    46201 aaaactagtg gaggaagcta ttatgccatt tgtacgcatc gatttatttg aaggacgcac
    46261 gctcgagcaa aagaaagctc ttgctaagga agtaacggaa gcggttgttc gcaacactgg
    46321 agcacctcaa tctgctgttc atgtcatcat caacgacatg ccagaaggaa cttatttccc
    46381 acaaggggaa atgcgcacca aataagctag cttaagcaga attgcttagg ctttttcaat
    46441 ctccaagtag cacccattga agaaatagtc taaatttgtt acaatttgaa aagagacttg
    46501 gaaaattcca agaaaagagc aattaattaa aggaaacatt atgattacac gtgaatttga
    46561 taccatcgct gctatctcta ctccactagg tgaaggggct attggtattg tccgcctgag
    46621 cggaacagac agttttgcta ttgtgcaaaa gatttttaaa ggaaaagact tgaacaaggt
    46681 tgccagccac actctcaact acggtcacat tattgatcct ctgactggta aagtcatgga
    46741 cgaggttatg gttggggcta tgaagtctcc aaagaccttc actcgtgagg atattatcga
    46801 gattaacacc cacggtggga ttgcggtgac caatgaaatt ctccagctag ctattcgtga
    46861 aggggctcgg ttggcagaac ctggtgaatt taccaaacgt gcttttttaa acggtcgcgt
    46921 agacttgaca caggcagagg ctgtgatgga tatcatccgt gccaagactg acaaggccat
    46981 gaacattgcg gtcaaacaat tagacggctc cctttctgac ctcattaaca atacccgtca
    47041 agaaatcctc aatacacttg cccaagttga ggtcaatatc gactatcctg aatatgatga
    47101 tgttgaggaa gctactactg ccgttgtccg tgagaagact atggagtttg agcaattgct
    47161 aaccaatctt cttagaacag cccgtcgcgg caaaatcctt cgtgaaggaa tttcaacagc
    47221 tatcatcgga cgtcccaacg ttgggaaatc cagccttctc aacaacctct tgcgtgagga
    47281 caaggctatc gtaacagata tcgctgggac aacacgagat gtcatcgaag agtacgtcaa
    47341 catcaatggt gtacctctca aattgattga tacagccggt attcgtgaaa cagatgacat
    47401 agtggaacaa atcggtgttg agcgttcgaa aaaagccctc aaggaagccg acttggttct
    47461 actagtgcta aatgccagtg aacaactgac tgcgcaagac agacaacttc ttgaaattag
    47521 ccaagatacc aatcgcatta ttctacttaa taaaaccgac ctgccagaaa cgattgaaac
    47581 ttcgaaacta cctgaagacg ttatccgtat ttcagtcctt aaaaaccaaa acatcgacaa
    47641 gattgaagag cgaatcaaca acctcttctt tgaaaatgct ggcttggtcg agcaagatgc
    47701 tacttacttg tcaaacgccc gtcacatttc cctgattgaa aaagcagttg aaagcctaca
    47761 agccgttaat caaggtcttg agctggggat gccagttgat ttgcttcaag ttgacttgac
    47821 tcgtacttgg gaaatcctcg gagaaatcac tggggatgct gctccagatg aactcatcac
    47881 ccaactcttt agccaattct gtttaggaaa ataagaaaaa tccatgatcc ttcattcggt
    47941 catggatttt attgtcttta ttagtaatct ggtcttaaga cccctgttac agttgcctta
    48001 gttgcttcgt agtcgccatc tacgacaacc ttgataatgc gtttggcatc ttcttctggt
    48061 gctggaacaa gaggtagacg agtgggtcca gcttcaaatc ccatatagtt aagaattgcc
    48121 ttaactggag caggacttgg ataagagaag agagcattaa ccttaggaat gaatttacgc
    48181 tgaattgctg cggctttctt catatcgctt tctgcaatgg cagtaaacat ctcgtgcatt
    48241 tcatccccat ttgtatgaga ggcaacagaa ataaccccat ccgccccaag gttcatggca
    48301 tggaaagcat ctccatcctc acctgtataa atcaagaact cttcaggctt gtgctcaatc
    48361 aagtaagcca tattagccaa gctagtacat tctttgacac cgataatatt tggatggtca
    48421 gccaagcgaa gcatggtttc tggagtcaat tcgaccacta cacgccctgg aatgttatag
    48481 ataataattg gtaggtcaga agcatctgca atagccttaa agtgctgata catcccttct
    48541 tgagaaggtt tgttgtagta aggaacaata gcaagcccag ctgcgaaacc accaaattcc
    48601 gctacttctt tgacaaactc aatagagtca cgcgtatcat tagtacctac acccgcaatc
    48661 aaaggaacgc gtccattgac aaccttttgt acagccgcaa acaactccaa ctcctcatcg
    48721 tgggtcaaag ttggactctc agcagtcgtt cctgcgagaa gaattccatc cgtatgatgg
    48781 gccaataaat gctcaatcaa ggctggaata gcatcaaagt taatggaacc atcctcatgg
    48841 aagggggtaa taaaggctgt aatgatttta cattctttta aatcttgata agacacgaaa
    48901 acacctctct atttcaaaga aggagttcat ctgaactcct aaacgatatg actattttaa
    48961 ttcaaatttc aattcagctg ttggacgaac caatccacgt tcatgaagag tttcagcaat
    49021 ctgaactgag ttccaagcag cacctttgag aaggttatct gaaacaaccc acatgtgaat
    49081 tcctttttct gcatccaagt ctttacggat acgaccaaca aaggtatcac gtgaaccaac
    49141 tgcattgatg gcttgaggat agatttgatg aactacatca tcttcaagaa cagcacctgg
    49201 gaaggatgcg atagctgctt tgacttcttc aattggagcc acttcctttg tttcaatata
    49261 aactgactca gagtgagctg acaagactgg aatacgcaca catgtcgcag atactgcaat
    49321 gctatcatct tccataattt tcttagtttc cttggtcatc ttcatctctt cgtacgtgta
    49381 atcattatca gtgaagacat caatttgtgg aagagcgtta aaggcgatag gataatgttt
    49441 cttgtcacca cctgaaggca agatttccgc atgcaaatca cgtggtttca ctccatcatt
    49501 caagacctca cgaagttcac gttgtgtctc aagaattgct cccataccag cacctgaaac
    49561 ggcttgataa gttgaaacaa tgatacggtc caagccccat ttttggcgaa ccggctcaag
    49621 agccaccatc atttggattg ttgaacagtt agggcaggca atgattccgt tgtgggcatc
    49681 aagtgcatga gcattgacct ctggaacaac caaaggaaca tctggatttt gacggaaata
    49741 agatgtatta tccactacta ccacgccagc ttttactgcg tatggtgcat acttagctga
    49801 tgtcgaacca cctgctgaaa agagagcaat atcaactcct tcaaaagctg tttcagtcgt
    49861 ttcttcaatc gtaatatctt gatctttaaa tttcaatgac ttacctgctg aacgtgcaga
    49921 agcaaggtaa cggattttat cgattggaag tgttgattct tccaacattt ttatcatctg
    49981 agcaccgaca gcacctgtcg cgccgactac agcaactgta tatcccataa ataacctctt
    50041 tcggaatttt ctaaaaattt ctataataga agtattatac tactttttcc atgaattgca
    50101 aagctttttc atcatttttt ggaaaataaa aatccccaat cgctagacta gggattaaga
    50161 ggcatcttca tgtgatgagc aggttcacac aactcatcaa ggtccgctcc tgcgttatga
    50221 cctccttatg ctcaatagta gcccgaagac tacctatcga ctcatcgcat ctactattct
    50281 actaaagaga atgacttttg tcaacagacg aaactcttta tactcttcga aaatctcttc
    50341 aaacttcgtc agcgtcgcct tgccgtatgt atggttactg acttcgtcag tttcatctac
    50401 aacctcaaaa acatgtttta agctgacttc gtcagttcta tctacaacct caaagcagtg
    50461 ctttgagcaa cctgcggcta gtttcctagt ttactctttg attttcattg agtattagtt
    50521 ttatttacac aggtgcataa gaaatatatt ggaaaaattg ggggcagaca taacaaaaac
    50581 ccttgtaaat caagggcttt tctgtctatt taatgctaat tgccgggatt gaaccggcga
    50641 cctcatcctt accatggatg cgctctgcca actgagctaa atcagcttac ttaagaagta
    50701 tactatattc agaaaaactt gtcaagtttc cttagaaatt ttccatagga aaaagccagg
    50761 taagaactac ctagcttatc ttcttctatt tacttaaatc aattcgacga ccaattttac
    50821 caataataat cgctccaata atcaatgaag caaattcacc gattcctgtt gtaaaccaag
    50881 taaggaagaa tggtaattct gctacaatat ttaactctgc agcgatagta aacatggaaa
    50941 ttgaaaagag gattgaaaag aagaaatgat cttttcgaat caatccgtta aagaggtaat
    51001 ccttgctata ttttgcaaaa agccaaacac ctaaactgag gaatactaag gttgaaccac
    51061 caccaacaaa gacatctagc agtccgaagc taaagaaatt agcaatcata caaccgatgg
    51121 taactccgat gatgtactta ggattgtaaa aagccataaa gttcatcatt tctgaaatac
    51181 gaaactgata agcaccatag ctgatggcat ttaggggcgg tgtgacagtc aaaacgacgt
    51241 agatagcagc gacgattgca atatctgcaa catcacgaat agttaatttt ttcatctttt
    51301 ctcctttggc ggttatccgc gtgtaatatg cttggtgaaa gaagctaagc accaagggtt
    51361 gattcattca accttactag tatagcacaa tagcctgctt tatgctatac ttaaagcatg
    51421 aaaaaaccta ttcaaaaatt ttttaacaat gaaatcttag cctatctctt ttttggcctt
    51481 gcgacaactc tagtttcgat tctctcacga ctagtcattt atcaactaag tcatcaggaa
    51541 ctccttgcta cggccttggc aaatattatc ggtatcttat ttgcctttat cacaaatgat
    51601 acgattgtat ttaagcaaaa aaagaaaaat agacttatcc gtttagtgaa attttctctt
    51661 gctcgccttt ctacttttct gttagacttg tttttaactt ttctctttgt aacccaattt
    51721 cctcacatca tagggcaatt cgtaactgaa aacattgata agataaatgc tattgaaaca
    51781 ataattgcac aaatattcat tattatcatc aattatatct tgagcaaggt ctatattttt
    51841 agaaaataat gctccattta tgagcctttt aattgccttc tataatgatt taggatacaa
    51901 tgaaacacga aacattgaaa ggaaaacagt atgttaaaaa atctaaaatc gttcttgctt
    51961 cgaggaaatg ttattgacct tgctgtcggt gttgtcattg cctctgcttt tggtgctatc
    52021 gttacttcac ttgtaaacga cattatcact cctcttattt taaatcccgc tttgaaagct
    52081 gctaaagtcg aacgtatcgc tcaactttct tggcatggag tcggctatgg taacttttta
    52141 agtgctatta tcaattttat ctttgtgggt accgccctct tctttattat caagggcatt
    52201 gaaaaagcac agaaactgac tggcataaag aaagaaaaaa ctgccgaaaa aaaaccaacc
    52261 gaattggaag tccttcaaga aataaaagct ctccttgaga aaaaataatc gattaaaagg
    52321 atctagcgca aagctaaatc cttttttctt tactctttgg gtaacttgcc tgctttttca
    52381 agcatttttt tgataagata aggcatctta acattctccc gccctttttt ctcaatcagt
    52441 tttttcacaa attctggcat ttgtaaatct tcagattcag ctaaaatgtt tttcgtctcg
    52501 tctgaaggaa ctaactcatc aaaggtctct tcttctggga gaaattcctt aaactcttga
    52561 ttttcattga ctctaactgt attgaccaaa gcatcaatca aacgagaatc tgtatttggc
    52621 attggtggac gatggtagtt taccccaaat tcctggcata agtcataaca ttctacatca
    52681 ttgtcaaaca agacctcaat atgctcactg atgaaactaa taggtacaaa aatataatgg
    52741 tctggatgtt ctgtctgttc tctgagatac tccaaaacat ctggtttaat ccatggaata
    52801 ccaatatcac tctcactctg ccaagtgttg gtatattgtt ctgaactcaa gcccagtttt
    52861 tcagcgacta gcttgctatt ttcgaaaatt tggtctatat aaggatcacc aaagtccaag
    52921 gcaaaaatgg gcacactatg ggctgaaaag atgactttaa agctgtcttg ctttacttct
    52981 tcttttaaaa tcttagcaat ttcatctgcc caatagttta agagcgcttc ttcctgatac
    53041 cagtccttaa tgaccaaaaa ttgaatttgt ttgctttcta aaaatttttc atagcccatg
    53101 acagagtaga aagaataatg gggctccaaa atcaagcaaa tacactgttc aattccgtct
    53161 gcttccattt gaccgatcac atctggaata aagggactgg aaaacttatt agcaaagtag
    53221 acactgtatt cattccccag cctagcttct accaaggcaa cctcttgacg ggtaattttt
    53281 tgcagaggcg tgcctccaat tcgtacataa ttatcataga gagtctgaat ctcgtggtct
    53341 tggggtctca ccccacgacg aatatttgtg aaaaaatcag ctacaccttc aaaggtaatc
    53401 tcttctggtg aaccgaaggt catcattaaa attgcttttt tcatgactgc ttccttgtga
    53461 tgtttttatc aagtttattt tatcattaat taatcgataa gtaaacgcta atatagggac
    53521 attctcaatc ttctgtcttt tgtttttctc ttctttctat gatacaatgg aaaaaataaa
    53581 ttcaaaagga gtttttttat gacttatcca aatctcttgg accgcttctt aacctacgtt
    53641 aaggtcaaca cgcgctctga tgaacactct actactactc caagtacaca gagtcaggtt
    53701 gacttcgcaa caaatgtcct aattcctgaa atgaaacgtg ttggactgca aaatgtttac
    53761 tatctaccga atggttttgc tattggaacc ttgccagcca acgatccgtc tttaacacgt
    53821 aagattggtt ttatatcgca catggatact gctgatttta atgctgaagg agtcaatcca
    53881 caggtaattg aaaactacga tggtggtgtg attgaactag ggaattctgg tttcaaactc
    53941 gatccagctg acttcaagag tcttgaaaaa tatccaggac aaacgctcat cacaacagat
    54001 ggaacaagct tgctaggtgc tgatgacaag tcaggaattg ctgaaattat gacagccatt
    54061 gaatatctaa ctgctcatcc tgaaattaag cactgtgaga ttcgtgttgg ttttggtcca
    54121 gatgaagaaa tcggtgttgg tgccaataaa tttgatgcag aagattttga tgtggatttt
    54181 gcctacactg ttgatggtgg tccactaggt gaacttcagt acgagacttt ctcagccgct
    54241 ggtgctgaat tgcatttcca aggccgtaat gtccaccctg gtactgccaa agagcagatg
    54301 gtcaatgccc ttcagctagc aattgatttt cataatcaac ttccagaaaa tgaccgacct
    54361 gagttaactg aaggttacca aggtttttac catctaatgg atgtgacagg tagtgttgag
    54421 gaggtgcgtg caagctacat cattcgtgat tttgaaaaag atgcctttga agcgcgtaaa
    54481 gcatccatgc aatctatcgc tgataagatg aatgcagaac ttgggagcta ccgtgtcact
    54541 ctcaacttga cagaccagta ctacaatatg aaagaagtca ttgaaaaaga tatgactcca
    54601 attaccattg ctaaagccgt tatggaagat ctaggtatca cgcctattat cgaaccaatc
    54661 cggggtggaa cagacggctc taagatttcc tttatgggaa tcccaactcc gaatatcttt
    54721 gcaggtggcg aaaatatgca cggacgtttt gaatacgtta gccttcagac tatggaacgt
    54781 gcagttgata ccatcattgg catcgtagct tataaaggct aaaaagacga ggtagctcag
    54841 ctacttcgcc tttcttttta ttctactggt ttttcttgat ttccagtagt tgtagaagat
    54901 tctgttgttt cattttctga agttgattca gcaggtttag aatctcttgt attgcttggt
    54961 ttgttttcgt cgctagcaat ttcaatgtta gattctgcag ttgcgtttgg ttggttctca
    55021 gcactggtgt tatcactatt tgcttcagca tttcttgctg gacttgtttc ttcacttgcg
    55081 ctagcttttg actggatttg atgattcaaa actagaatag cttttgtcga ttcaagtaaa
    55141 gctgttttgt ctttactctt agcagaaagt tgatctaata atgcatccac cttatcaaag
    55201 tccgcatcag atccattatt actttctaaa taagagtgaa gcgacatgag aatatcgtag
    55261 agtttttgat agagtacaag tgtctgagaa tcttgctcag cattttcctt ttcttgttga
    55321 agggcgctag cgatacgagt caagacatct tttacctgac tgtttacttc atccaagtct
    55381 gcatcagcct tgtttgtggc agcttttaga ttttctactt cttctgccaa ggattgtctg
    55441 attccttctt catggatttg ttccaagagt tgatttacct tgctcaaaag actttctact
    55501 tcttccttgc tatctgtcgc agattattgg ttgccatcta ccatgtactc ctaaaacagg
    55561 agagttataa tccaagatta caaggcctta cagaaataag aaatccagat aagacaatgt
    55621 tcgtccaaga cgctattcgc ttcgcacagc agcacggatt caatatgctt taattttaaa
    55681 gtttaggtgt caagacctct ttttagtgtg cccaaaattt agagaagtaa tcaatcaact
    55741 aacttttatt tttttcaaac tttcagtaaa ctgacctaaa gctaactcaa tctgtctttg
    55801 tagatgcttc tgctatcagc tagaagttga tctacttttg ccaagactgc cttctcatca
    55861 aaagttccag gttgatagtt ggattgcagg gatggaatct tgtttttcaa agccgcttca
    55921 tatcccttag tttgaacctt gatgtagtga ttgtggtcgc catgaggaat cacaaaacct
    55981 tctgaatctt cacttataat tcgattggca tcaaaaccat gaccatcttc ttcctcatgg
    56041 tggacatgta gtgacggatt acttaataca gaactagaag aacttcctgc ctcttccgtg
    56101 ttagagtgtg atgggggatt gttaagagat gacttaggaa tataatgata gtgatccccg
    56161 tgtcttacta tataagcatc acctgtatct ctgacaatat cattagggtt aaagacataa
    56221 ccatcatctg ctgcagaaac accattattc ggtgtcaccg acaaagattg actgagagct
    56281 gtagtattcc ctgataatta tacttttgca gctgctaatt cacctgccga caagtcactc
    56341 tcaggaatga aatgatagtg accaccatgt ggtactatag taggttgaaa tagaatatga
    56401 gcaaattgat aaggggattt taaagtaatt tctaacaatg atttagaaac tatgatgtgc
    56461 tattctaaat tcaactcact atatataacc atcatcggta gtataacgtc cctgtaattt
    56521 tgctacagat acttctgcac tagctccttt atcgtcttta ccatgttctt gtttttggcg
    56581 attgatttca tcttttgttc gtacattttc tgcatgagct tgatctttaa ggtaaacata
    56641 atactttcca tctaccttaa taatatatcc tcccttaacc taactgacga tatcttgatc
    56701 tttcggctga tagttggggg ctttcattaa tagctcttca ctaaagagcg catcaaaagg
    56761 aactttacca ttatagtagc gataatgatc gccatgagaa gttacataac cttgatctgt
    56821 aatcttaata acaatttgtt ttgcttgaat tccttctttt tgactaacct agtctggagt
    56881 caaattttca gtcttcttag tgtctttatt actgtttaca tatgaaacac gatttttatc
    56941 tgtattggcc tgttagctat gttggttcag agtataaaca cacagactta aggaaaggat
    57001 aacaacagat ccagctgcta tatatttctt ttta
//
LOCUS       DAVMJI010000011        55519 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.011, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000011 DAVMJI010000000
VERSION     DAVMJI010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.011"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(198..335)
                     /locus_tag="VYR58_000793"
                     /pseudo
     CDS             complement(198..335)
                     /locus_tag="VYR58_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(713..1402)
                     /gene="rplA"
                     /locus_tag="VYR58_000794"
     CDS             complement(713..1402)
                     /gene="rplA"
                     /locus_tag="VYR58_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV3621988.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1610..2035)
                     /gene="rplK"
                     /locus_tag="VYR58_000795"
     CDS             complement(1610..2035)
                     /gene="rplK"
                     /locus_tag="VYR58_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV3621989.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2167..2304
                     /locus_tag="VYR58_000796"
     CDS             2167..2304
                     /locus_tag="VYR58_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3621990.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(2344..3060)
                     /locus_tag="VYR58_000797"
     CDS             complement(2344..3060)
                     /locus_tag="VYR58_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV3621991.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3063..3533)
                     /locus_tag="VYR58_000798"
     CDS             complement(3063..3533)
                     /locus_tag="VYR58_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV3621992.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLEKETRLRFLEEMSLIQEAVAKAFTAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(3535..4572)
                     /locus_tag="VYR58_000799"
     CDS             complement(3535..4572)
                     /locus_tag="VYR58_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV3621993.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDGQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KEQNIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYIKSALVD"
     gene            complement(4670..5995)
                     /gene="brnQ"
                     /locus_tag="VYR58_000800"
     CDS             complement(4670..5995)
                     /gene="brnQ"
                     /locus_tag="VYR58_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV3621994.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6166..6258)
                     /locus_tag="VYR58_000801"
     CDS             complement(6166..6258)
                     /locus_tag="VYR58_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV3621995.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6301..6453)
                     /locus_tag="VYR58_000802"
     CDS             complement(6301..6453)
                     /locus_tag="VYR58_000802"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV3621996.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6613..7191)
                     /locus_tag="VYR58_000803"
     CDS             complement(6613..7191)
                     /locus_tag="VYR58_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV3621997.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7245..8645)
                     /gene="pepV"
                     /locus_tag="VYR58_000804"
     CDS             complement(7245..8645)
                     /gene="pepV"
                     /locus_tag="VYR58_000804"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV3621998.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8658..9263)
                     /locus_tag="VYR58_000805"
     CDS             complement(8658..9263)
                     /locus_tag="VYR58_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV3621999.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            9434..10234
                     /locus_tag="VYR58_000806"
     CDS             9434..10234
                     /locus_tag="VYR58_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV3622000.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10416..11249)
                     /locus_tag="VYR58_000807"
     CDS             complement(10416..11249)
                     /locus_tag="VYR58_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV3622001.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDCVLEVLDGQYGLENPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11239..13083)
                     /gene="uvrC"
                     /locus_tag="VYR58_000808"
     CDS             complement(11239..13083)
                     /gene="uvrC"
                     /locus_tag="VYR58_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV3622002.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQGESLPQVAEERVDYQTEGNHNEP"
     gene            complement(13122..13823)
                     /locus_tag="VYR58_000809"
     CDS             complement(13122..13823)
                     /locus_tag="VYR58_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV3622003.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCALAFGFLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWERTGQLPKLNQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYVEAIQNWNQTGAFNFEIVTESSTADILATEMNNGNTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPNYGYSYERLVHTAEHELGHAIGLDHTDGKSVMQPAGSFYGIQ
                     EEDVTNLRKIYETSE"
     gene            complement(13902..15134)
                     /gene="murN"
                     /locus_tag="VYR58_000810"
     CDS             complement(13902..15134)
                     /gene="murN"
                     /locus_tag="VYR58_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV3622004.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNSIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15139..16359)
                     /gene="murM"
                     /locus_tag="VYR58_000811"
     CDS             complement(15139..16359)
                     /gene="murM"
                     /locus_tag="VYR58_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV3622005.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16471..17250)
                     /locus_tag="VYR58_000812"
     CDS             complement(16471..17250)
                     /locus_tag="VYR58_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV3622006.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17319..18980)
                     /locus_tag="VYR58_000813"
     CDS             complement(17319..18980)
                     /locus_tag="VYR58_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV3622007.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19155..21377)
                     /gene="recJ"
                     /locus_tag="VYR58_000814"
     CDS             complement(19155..21377)
                     /gene="recJ"
                     /locus_tag="VYR58_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV3622008.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPYRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYRFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21654..22412
                     /locus_tag="VYR58_000815"
     CDS             21654..22412
                     /locus_tag="VYR58_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV3622009.1"
                     /translation="MALVEFKNVEKYYGDYHALRDINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LSPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDMTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22452..23216
                     /locus_tag="VYR58_000816"
     CDS             22452..23216
                     /locus_tag="VYR58_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV3622010.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23229..23906
                     /locus_tag="VYR58_000817"
     CDS             23229..23906
                     /locus_tag="VYR58_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV3622011.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23916..24575
                     /locus_tag="VYR58_000818"
     CDS             23916..24575
                     /locus_tag="VYR58_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV3622012.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24870..26060
                     /locus_tag="VYR58_000819"
     CDS             24870..26060
                     /locus_tag="VYR58_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV3622013.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26381..27262)
                     /locus_tag="VYR58_000820"
     CDS             complement(26381..27262)
                     /locus_tag="VYR58_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV3622014.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27403..28731)
                     /gene="vncS"
                     /locus_tag="VYR58_000821"
     CDS             complement(27403..28731)
                     /gene="vncS"
                     /locus_tag="VYR58_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV3622015.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(28728..29384)
                     /gene="vncR"
                     /locus_tag="VYR58_000822"
     CDS             complement(28728..29384)
                     /gene="vncR"
                     /locus_tag="VYR58_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV3622016.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29433..29519)
                     /gene="pep27"
                     /locus_tag="VYR58_000823"
     CDS             complement(29433..29519)
                     /gene="pep27"
                     /locus_tag="VYR58_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV3622017.1"
                     /translation="MYEKGFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(29695..31074)
                     /gene="vex3"
                     /locus_tag="VYR58_000824"
     CDS             complement(29695..31074)
                     /gene="vex3"
                     /locus_tag="VYR58_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV3622018.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31126..31773)
                     /gene="vex2"
                     /locus_tag="VYR58_000825"
     CDS             complement(31126..31773)
                     /gene="vex2"
                     /locus_tag="VYR58_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV3622019.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31786..33063)
                     /locus_tag="VYR58_000826"
     CDS             complement(31786..33063)
                     /locus_tag="VYR58_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622020.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELEMVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(33419..33589)
                     /locus_tag="VYR58_000827"
                     /pseudo
     CDS             complement(33419..33589)
                     /locus_tag="VYR58_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(33732..34331)
                     /locus_tag="VYR58_000828"
     CDS             complement(33732..34331)
                     /locus_tag="VYR58_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622021.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNLSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNTK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(34468..35352)
                     /locus_tag="VYR58_000829"
     CDS             complement(34468..35352)
                     /locus_tag="VYR58_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV3622022.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(35356..35742)
                     /locus_tag="VYR58_000830"
     CDS             complement(35356..35742)
                     /locus_tag="VYR58_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV3622023.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(35735..37078)
                     /locus_tag="VYR58_000831"
     CDS             complement(35735..37078)
                     /locus_tag="VYR58_000831"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV3622024.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(37165..38049)
                     /locus_tag="VYR58_000832"
     CDS             complement(37165..38049)
                     /locus_tag="VYR58_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622025.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYQLAKLSNLEVLLADSSY
                     QEQISQLKFQAFSGEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(38061..38678)
                     /gene="cysE"
                     /locus_tag="VYR58_000833"
     CDS             complement(38061..38678)
                     /gene="cysE"
                     /locus_tag="VYR58_000833"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV3622026.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(38694..40907)
                     /gene="pnp"
                     /locus_tag="VYR58_000834"
     CDS             complement(38694..40907)
                     /gene="pnp"
                     /locus_tag="VYR58_000834"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV3622027.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(41594..42460)
                     /gene="metF"
                     /locus_tag="VYR58_000835"
     CDS             complement(41594..42460)
                     /gene="metF"
                     /locus_tag="VYR58_000835"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV3622028.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(42524..44773)
                     /gene="metE"
                     /locus_tag="VYR58_000836"
     CDS             complement(42524..44773)
                     /gene="metE"
                     /locus_tag="VYR58_000836"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV3622029.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLADHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKAEDFVDSLVAAYQEVFAKLAELGASRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVKLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPAILNHFAFAVEKLDEIRDLDAIRNGQGEEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEVILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(45034..45300)
                     /locus_tag="VYR58_000837"
     CDS             complement(45034..45300)
                     /locus_tag="VYR58_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3622030.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVPLEQGKS"
     gene            complement(45426..45829)
                     /locus_tag="VYR58_000838"
                     /pseudo
     CDS             complement(45426..45829)
                     /locus_tag="VYR58_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            45985..46986
                     /locus_tag="VYR58_000839"
     CDS             45985..46986
                     /locus_tag="VYR58_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV3622031.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(47159..49564)
                     /locus_tag="VYR58_000840"
     CDS             complement(47159..49564)
                     /locus_tag="VYR58_000840"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV3622032.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIEFSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVSLLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(49641..50150)
                     /locus_tag="VYR58_000841"
     CDS             complement(49641..50150)
                     /locus_tag="VYR58_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622033.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(50150..51196)
                     /gene="pheS"
                     /locus_tag="VYR58_000842"
     CDS             complement(50150..51196)
                     /gene="pheS"
                     /locus_tag="VYR58_000842"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV3622034.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHHHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(51788..53203)
                     /locus_tag="VYR58_000843"
     CDS             complement(51788..53203)
                     /locus_tag="VYR58_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV3622035.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(53216..55054)
                     /locus_tag="VYR58_000844"
     CDS             complement(53216..55054)
                     /locus_tag="VYR58_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV3622036.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     MKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(55072..>55519)
                     /locus_tag="VYR58_000845"
     CDS             complement(55072..>55519)
                     /locus_tag="VYR58_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV3622037.1"
                     /translation="LGKRALQIIKKELGIELPIDEAAFIALHFVNANLENNFQESYKI
                     TEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVENTTYCDDDDEDLLALM
                     KNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTKNLD"
BASE COUNT        15859 a        12546 c        10246 g        16868 t
ORIGIN      
        1 agtcagtaac catacgcacg gcaaggcgac gttgacgtgg tttgaagaga ttttcgaaga
       61 gtattagaaa gctcgatgga ctattccaga ttcattccac tagatttcga aatcgagtag
      121 gggataatct ctagcccctc tcacaccacc gtacgtgccg ttcggcatac ggcggttcaa
      181 ctaactgtta acgcatgtca ttcaaggtaa taatccaaac acgaaaccag tccacgtttt
      241 tcaaggactg gttttgatat agcacgttta agtaccgact tctgagctac taattgatag
      301 tggtcgcccc agccagatac cttatccgct atataggcct tattatcacg ttcctgttcg
      361 tagagccacg atttcgctat cccttcctct gacgattctt atttccagcg tcagacttaa
      421 aacggtctat ccccagaccg ttttaatccg ctacctcacg atagtcagac ttgggaatcg
      481 ctattgggtt caccggtagc aggtgcccac cgaggactta cacctcaaat atataataaa
      541 atgaaataag aataggacga atcgatcagg acagtcaaat caatttctaa caatgtttta
      601 gaagtagatg tgtactattc tagtttcaat ctactataca acatgcccgt cgtacatcaa
      661 aaaaagttga gacatagcgt cttcaacttt tttacattac tttaactact gattaaagtg
      721 agtttacgtc aactttgata ccaacacctt gagtagttgt gatagtcaag tttgttacgt
      781 aagttccttt agctgtagct ggttttgctt tttggattgt ttcgttgaaa gctttaaagt
      841 tttcaaccaa tttttcagct tcaaatgata ctttaccgat gattgcttga acgttacctg
      901 cacggtcagc acggtaagtg attttaccac ctttagactc ttcaactgct ttagcaacat
      961 ccattgttac agtaccagtt ttagggtttg gcatcaagtt acgtggtcca aggacacgtc
     1021 caagacgtcc aacaagagcc atcatatcag gtgtagcgat aactacgtcg aagtccaacc
     1081 aaccgtcgtt gattttagca acaaggtcat cttcaccaac aaagtctgca ccagcagctt
     1141 ttgcttcttc agcttttgca ccacgtgcga aaacaagaac acgtgaagtt ttaccagtac
     1201 cgtttggcaa taccattgct ccacggattt gttggtcagc ttttttaacg tcgatgttca
     1261 agttgtaagc aacttctaca gttgcatcaa attttgcaaa gttagtttct tttgcaagtg
     1321 ctacagcttc ttctacactg tatgcttttg tgctgtcgat tttctcaaga gcagcacgaa
     1381 gttgtttgct ttttttagcc attttctatt ctccttgtaa gtggttcaat cgattttcat
     1441 ctcccacgtc acttctcgaa atgatgaagt cttgcgggtt ttcagtctac tatttttctc
     1501 ttcctacggc cttaagctcc cttgctgtac ccaagtacaa gcctcagtca cttgcctagt
     1561 atgaaaagca actaatagac tgctgtgaga ttttctactg tgttattgat tagtcaacaa
     1621 cagtgaatcc catagaacga gcagtacctt cgatcatacg cattgcagac tctacgtttg
     1681 ctgcgttcaa atctggcatc ttagtttctg caatttcttg tacttgtgca cgagtaactg
     1741 tagcaacttt agttttatta ggtgtacctg atcctttttc aacacctgca gcttttttca
     1801 aaagaacagc agctggtggt gttttcgtaa cgaaagtaaa tgatttatct tcgtaaactg
     1861 agataacaac tggaatgatc ataccagctt ggtcagctgt acgagcgttg aactcttttg
     1921 tgaatcccat gatgttgata ccagcttgac caagagcagg tccaaccggt ggagctggtg
     1981 tagctttacc agcagggatt tgcaatttta caagtttttc gactttttta gccattttta
     2041 aatcctcctt tgtggttttg gcggtaatta gagattttta cctcccacaa gtatgttttt
     2101 cacataccca tccattatac actatttatc tggaattgca agagaaaagt ttatttttta
     2161 tactcaatga aaatcaaaga gcaaactagg aagctagccg caggctgctc aaaatacagc
     2221 tttgaggttg cagataaaac tgacgaagtc agctcaaaac actgttttga ggttgtgaat
     2281 agaaccgacg cagtcagtag gtaaggcgac gctgacgtgg tctgaagaga ttttcgaaga
     2341 gtattaatcg acgtagtctc cgccttcaaa gccatagtat tcttccaaac tgagaccgct
     2401 tgcagcaatt tctttagctt cttttcctac ataacgcagg tgccattcct cagccatata
     2461 gcctgtttcc ttttccttgc ctttgagata acggacaaca aagccataat cagctgcatg
     2521 gtccaagagc cattgggctg ctttttcttc tgtcaccaaa tcaccatcag tcccaatcac
     2581 atcaaaggcc aagcctgtct ggtgttcgct atagccagga cgggcagagt aacggtcagc
     2641 tgctgccttt ccatcttggt tgacataatc ttgatagagc ttggtctgag tttcataact
     2701 tctaaaacca ctgtaatgat cactaatagg gaaacctgcc tcttgcatcg ctttgatgag
     2761 tttgaccaac tcagccttgg ctgttggatt ttccccggga ttatagtctt tcgacaaagg
     2821 ataatgttta ttggctacga tgatttcgtc gtattttcct tggatgctgt agtaatcacc
     2881 tttattgacc acttctgctt ttttctgggc agccccttga gacttactgc cgactgtccc
     2941 atcagctttg gctgtctgtt ctgtcttagc tgtgccatct tcattttttg ctttttcttg
     3001 tgaacaagct gctagactca aggctagcaa ggctgtcacg acaaggtatc ttttcttcat
     3061 ttctactcct ttatttctaa tagtttatct acttctgatg ataaacgttt gactaatctt
     3121 ttgatctcat ccggttttgc ttggcaggtt tctgctgtca tttcttcaaa aggaacccac
     3181 caaactggac cacgtccctt gagaccgtga ccattcatat cacctgtccg tcgtggaaac
     3241 agatgccaat gaagatgggc atcgccattt cctaaaagtt caatattcat tttctcagca
     3301 gtaaaggcct tagcaactgc ctcttggatt agactcattt cttcgagaaa acgtagtctt
     3361 gtttcctttt ctaaatggtg caattccgtg acgtgttcct tggctagaaa gagactatag
     3421 cctgcaaaat actggtgatc tccaatcaca agatagcctg tttccaactc tttgacaaaa
     3481 tagggatttt ctcccttctt gatgagctca attctctggc atataagaca catattagtc
     3541 taccaacgcg ctcttaatgt aagcatcaac catacgctct gttgcgacca ccgagtcaat
     3601 atgagtacgc tcataagaat gactagactc gatacccgcg ccaaggaggg cgtgtttgac
     3661 ctctgcccct gcggacatgg ccgctgaagc atccgaacca taaaatggat agatgtccag
     3721 cttaaaagga atattttgct ctttcgccaa ggtcaccaag tgttgacgga agtcatagtg
     3781 ataagggcct gaggcatcct tgacacagat agacactgtg tactcatctg tttgctggcc
     3841 atcgcccata gctcccatat caacagccag atattcgact acctgagcag gaatgttaga
     3901 attagcacca tgtcctactt cttcaaaaac tgaaaaagca aaatgagttg ttactggcaa
     3961 ttcaatcttc tctttcttat aaatacgaag caggttgagc aaaatcgctg cgctgacctt
     4021 atcatccaaa tgacgagact tgataaaacc tgtatcagtc acaacagttc gtggatcgaa
     4081 gctgataaaa tcaccgacct caatcccaag agcacgagtt tctttttcat tgcttacttt
     4141 tacatccaaa cgcacttcca tattgtcctg cgtgcgttct gcagttcctg catccttgta
     4201 gacatggcaa gaagtttggt ggatgaggat ggttcctgat accttttgac ctgtgctagc
     4261 cacatgaacg gtacagtttt caccttcaat catgttccaa ggaaaaccac cgatacggtc
     4321 caatttaaga cgaccatctg gtttgacagc acgaacaata gcacccagcg tgtccacatg
     4381 ggcagtcaca tagcgatgtt gctcatcatt ttgacctttg atggtcacat tgacaccacc
     4441 cttggctgtg cgaactggct ggtaaccaaa accttctaga gtcttgacta aataattcga
     4501 aatttcacga gtgaagcccg ttggcgatgc gatggctgtc agttctttga tatattctac
     4561 tgtttgattc atttcttcac ctctttcgct acctattata acacatttat catcggataa
     4621 aaaaagaaaa tcactcctgt agacttggct acaaaagtga tctaagtgat tattccattt
     4681 caaaaacatc gctttcttgc ttgtttggta gaaccaatga gagcaagatt ccaacaatgg
     4741 ctggcaccaa ccatgggaga gatgccttgg caaaaggaag aacgctaaca agatttgcaa
     4801 gaaactcaac cttaaacgag cttcctagta cgcttgcaat ggcaataact gtaaccacag
     4861 caattgtcaa ctgcatacct ggttttgaaa gggcaacaaa tttgttgaca atgacaatca
     4921 taacgatagc aatcgtgatt gggtacaaga taaccagtac tggaattgag tacttgataa
     4981 tcgcatcaag acccaaattg gcaatagcaa atccaatcaa ggtaaaggct gtcgcataaa
     5041 ccttgtagct gatttgtggg aagcgctcat taaagaactc agctgttgac acaatcaaac
     5101 caacagtcgt tgtgaagcag gttacggtaa ccatagctgc aaggaagagt tgagctgttg
     5161 agccaaagat ttcttgagtg gcttgtgaca agatgtaaac acctggtgtt ccacccttca
     5221 tcgcttcagc tggtactggg aaatgatttc caagaaaacc taaaccgatg taaagagcgc
     5281 tgaaggcaag ggcaacaacg ataccaacaa cccaaatagt tgaaatgtat tctttcttac
     5341 ttgaaaatcc aagttgtttc aaggtttgaa ctgcgattac gctaaaggcc actgaggcaa
     5401 gggcgtccaa ggtattgtaa ccttctagga aacctgtacc aaaggcagaa gcttgataag
     5461 cagctgaagc agcttgagga cttgttccac catatttgat agctcccaga acgaccaaga
     5521 taacaatcaa aattgcaaag actggcgtta aaatacgtcc aatgcggtct aagatttttg
     5581 atggattaag cgaaatcaaa taggctgccg caaaatacag aaccgtaaat acaatcaagc
     5641 caagtccttt atttgcatcc gacaaaaggg ggctaatccc tacttcgtaa gctgttgtag
     5701 cagtacgtgg ggtagcaaag aatggaccga ttgacaagta aagaactgag aggtaaagag
     5761 tcgcaaacca aggcgctatc ttcgttgaaa tctcgtagat atatccttta ggatttagcg
     5821 ttccaataat aagggtcaag acggcgatac caacgcctga aaagacaaaa cctgcgatgg
     5881 caggaagaaa atgttctcca gatagagcac ctagagaagg cggaaaaatc aagttccccg
     5941 caccaaaaaa tattccaaac aggagcaaac ctgttagggt acctttttta gccataaaaa
     6001 tctccttcat atttataaaa tactgaccta gtataccacg attaggagtc tgaaaaaagc
     6061 atcacgaggc aaatattaaa tgttttcaat tttcttaaaa ataagaatta tctaaaaata
     6121 aaactctcct acccagtcca caccaagtag gagaaatgca aaattttaaa gttcttcaaa
     6181 ggctaacatg ccaccctgga cattgataac attataacct tgttctaata ggaattggca
     6241 agcacgcgcc gatctcattc cagatttgca aataatataa tgcaagcgat ctttgtccaa
     6301 ttaatcataa ctatcagcca attgactaag cggtaggttg tgggcacctt ctaaatgaag
     6361 agctgcaaac tcatccactt ctctcacatc cactaaagaa agctggtcgt tttggtaaag
     6421 ctggtaaaat gcgtcaaagg ctatttcttt cattcttttt cttctaatac tcttcgaaaa
     6481 tctcttcaaa ccacgtcagc gtcgccttac cgtgcgtatg ttaccgactt cgtcagtttt
     6541 atctgcaact tcaaagctgt actttgagca gcctacgact agcttcctag tttgctcttt
     6601 gattttcatt gactataaaa tggttttaat tctttttttc aaatctggca ctacttctgc
     6661 ctcaaaccaa ggatttttgg ccatccagat ttgatttcgt ggtgatgggt gaactagcgg
     6721 aaaataggct ggcagatagt ctttatagtg tttcaccctc tccgttacct tcccactgat
     6781 tttctcctgt aaatagtagg cttgggcata ttgcccaatc aagagggtta actgaatatc
     6841 aggcaattcc tgtaagagct gcggatgcca tttttctgca aaacctgtac gaggcggaag
     6901 atcacccgac ttgccatgtc ctggaaagta gaaatccata ggcaaaacag caaaataacc
     6961 tgaattgtaa aaggtatctt catccacacc tagccagtcc cgcaagcggt caccactttt
     7021 atctttccag taaaggcctg cttcttgagt tttaagtccc ggagcctgac cgatgatatt
     7081 gatgcgagca gtttttggcg ctgcaaagag aggctcaatg ccacgctctg tatagctggc
     7141 attctgcgaa tccgccatga tagcctgttt gattctttcg atttgagaca tctactttcc
     7201 ctccaaaaag aagtccaagc ataagatctc agacttctat cgttttattt gatcaattcg
     7261 taaatagctt cggcataaat tgctgctgct cggaagagat cgtccaaggc aataaattca
     7321 ttggcttggt gcatggtatc aattgagtct gggaacatag caccataggc aactccgcgc
     7381 tctaacaagc gaccaaaggt tccaccaccg atgacttgtt catgaccttg taggcctgtt
     7441 tgtttttcat agacattcaa caaggtttgc acaagtggat cttccattgg cacatagtga
     7501 ggggtatgac catgttctga tagactgaca gaagcaactg gcaagttttc taggattgat
     7561 ttgatttgtt ctggacttgt tccttttgga tagcggatgt taagggcaat ggtattatca
     7621 gcacttgttt catcgaagcg gaagactccg gcattcatag aaagagcacc catcttttca
     7681 tccacatgag caatcttgag attttcaccc tcatgatcgt tcaagagaat tttacctgcg
     7741 atgtcaaggt agtctttggc tggaccagca aagccaaact ggctgaggaa gagggcaagg
     7801 taagttgcgc cattgacacc tgaagcaggc atagcaccgt gggctgattt accaatgatc
     7861 gtcaccttgt atttgccagc ttcttcttgg agttctcctc taagtttgtg ttctgcaaca
     7921 aaggcatcta gtttagcttg caagtcagcc aaatcacctg aaacgactgc tgttgctgat
     7981 tctggtacca tattttcacg taaaccacct gtaaagctgt gaagacgggc agcacctgta
     8041 ttttctcctg caaagtggag gtattccgtg atatttcctt tttcaccatt gatgattgga
     8101 aattcagcat ctggtgagaa accgaaatct ggtttggcaa gtcctacgtg ctcaaagtag
     8161 tagtccatgt ctgcccagcc tgattcttcg tctgttccaa cgatgaagcg aactttctta
     8221 gaagttggaa gacccaattc tttgatgatt ttcaaaccat agtaacaagc tgttgtagga
     8281 cccttatcgt ccgaagcccc gcgcgcataa aggcgaccat ctttgatagt tggtgtgtaa
     8341 ggatctgtat cccaaccgct accagctgga accacgtcca tatgggcaaa gattccgaga
     8401 acttcttctc catcaccaaa ctcaaaatgt cctgcgtagt tatcgacatt cttagttgga
     8461 taaccatcac ggtctgcgat ttcaaggaat ttttccaagg cttttactgg accaggtcca
     8521 aatggatgtt gggcatcagc cttgctatca tcacgttctg agttgatttc caaaaggcta
     8581 aacaagtcag ccaagaggtc ttctttgcgt ttttctactt ctgctgtaaa atcaattgct
     8641 atcatttttt cttcttccta tcttttttcg atgatttcat ctactggcaa gcggtagctt
     8701 ggttccaatt tgtcgtctgt gtaacccact gtgatcaaga gttctgggcg gaaacggtct
     8761 tcaatttcca aaacctcatt gacttttgat ttgtcaaaac caaggataat attggaacca
     8821 attccttggt ctgtaagagc gagaaccaag ttcatagcaa ccaaacctgc attgagtgct
     8881 aggtagtcgc tgacttgttg ttcattgtag cgtgcaaatt cagctggcaa atttttcatg
     8941 aagtattgaa gttgttcttc tgagaaattg ttagcaccac caactcgggc aatcttacga
     9001 gcgcgtttgg caaggtctgt atctgtaaat agggcaatgg ttacaggtgc tgatgatacc
     9061 tgctcaaagt ttgaaccata agccaacttt gccagttcag catttttctc acgaacaact
     9121 acaaatttcc aaggctggct gttgtgggcg cttggcgcca aggttgcaat ttcgatagcc
     9181 gtacgcacat cttttggatc aacaggctta tcagtgaaat gcttggtcgc atgacgtttt
     9241 ttatttaatt caagaaattt cataatcgat ttccttttct aattctactg cttccattct
     9301 accataattt gaaagagctt gcagggattt ttcatgatta agtttttcta tcacagacat
     9361 aaaagatata tattggttta tcaggaaagt ttctgataaa ctagcaagta ctttacattt
     9421 gaatggagac agtatgaaaa aatttagcct attactagct atcctaccat ttttggttgc
     9481 ctgtgggaat caagctacac ccaaagagac tagcgctcaa aagacaatcg tccttgctac
     9541 agctggcgac gtgccaccat ttgactacga agataaaggc aatctgacag gcttcgatat
     9601 cgaagttcta aaggcagtag atgaaaaact cagcgactac gagattcaat ttcaaagaac
     9661 cgcctgggaa agtatcttcc caggacttga ttctggtcac tatcaggctg cggccaataa
     9721 tttgagttac acaaaagagc gtgctgaaaa atacctttac tcgcttccga tttccaacaa
     9781 tcccctcgtc cttgtcagca acaagaaaaa tcctttgact tctcttgacc agatcgctgg
     9841 taaaacaaca caagaggata ccggaacttc taacgctcaa ttcatcaata actggaatca
     9901 gaaacacact gataatcccg ctacaattaa tttttctggt gaggatattg gtaaacgaat
     9961 cctagacctt gctaacggag agtttgattt cctagttttt gacaaggtat ccgttcaaaa
    10021 gattatcaag gaccgtggtt tagacctctc agtcgttgat ttaccttctg cagatagccc
    10081 cagcaattat atcattttct caagcgacca aaaagagttt aaagagcaat ttgataaagc
    10141 gctcaaagaa ctctatcaag acggaaccct tgaaaaactc agcaatacct atctaggtgg
    10201 ttcttacctc ccagatcaat ctcagttaca ataacactct tcgaaaatct cttcaaacca
    10261 cgtcagcttt atctgcaacc tcaaagctgt gctttgagca acctacggct agcttcctag
    10321 tttgctcttt gattttcatt gagtataaga tatactaaaa gcgattggac cagccaatcg
    10381 cttttttagt ttgcattggc tattttagga aactcttaca aaaaatcaaa aaaattcttc
    10441 acatcctcta catacccatg cttttctatt aagctggcta aaagttccag attgtgcccc
    10501 tgatagttat cgtcacgacg cagttcttca tacatttcaa taaagggaag ccccttggac
    10561 ttggccaatt ctaactcagc ctcgtaatca taagcaactt tacgaaattg gatattgacc
    10621 aattccccat cttcaacttc tatcacggca tactgggcac ggtgattttt taacgcctcc
    10681 caattaaaat agggcatgcc aatcgaccct ggattgatga tttgttgccc ttgacttcca
    10741 taacgaagca actgcttgtg aacatgacca taaactgcca cgtccgtttc cgcatctagc
    10801 agttggtcaa atttctctgt atcattctca actagcaagt caccaccata gttcttattt
    10861 ggcaaattat gagagataga aaagcgcagt ccagcaattt ctttcttttc cagcaaaggc
    10921 aagcttcgta gccagacagt cgttgcagga tccattcgct ccatcaaaaa ctgagtcatt
    10981 cgcatgagct ggatttcttg cggattttcc aaaccgtatt gcccatccaa gacctccagg
    11041 acacaatcat cccaattgcc tcgaacactg gctgtgatag gaaggtcctt tagcagggcg
    11101 actaagtcat ttgcgcctgg accaggaaga aaaatatctc ccagaagcca atattcactg
    11161 gccccttgat ttttagcatc tgcaatcact gcttctagcg ccgtcgcatt gccatgaaca
    11221 tctgataaaa ttgcgatttt atggttcatt gtggtttcct tccgtttggt aatctactct
    11281 ttcttctgct acttgaggca aggattctcc ctgcgggttc aactttcttt gcacagcctc
    11341 tgctactgct cttggtactc caacttcgac aatctcatcc acactggctt ccttgatttt
    11401 ggtcagagac ttgaagtgcc tcatgagatt ttgcttgcgt ttaggtccca gaccatcaat
    11461 cccatccaat tgagatgaga aagaattttt ggagcgcagt tggcggtgga aggtaatggc
    11521 aaagcggtgc acctcatctt ggatgcgttg gaggaggaaa aattcctgag aattgcgaga
    11581 caagtccacc acctcaagcg gatctccaaa gagcagttca tgggtttggt gcttatcatt
    11641 cttttgcagc ccagcaattg gaatatccaa gcccagttcc tcttggataa cctgcttagc
    11701 gatattgact tgaccttgcc ccccatcaat cacaatcaaa tctggaggag tcaaagcctc
    11761 acgctgtact cgaccatagc gtctgcgaat gacctctctc atgctggcat agtcgtctgg
    11821 tccaacaacc gtttttatct tgtacttgcg gtaatccttc ttactcggtt taccgttgac
    11881 aaagaccacc atagccgaaa cagggctagt tcccatgata ttagagttat cgaaggactc
    11941 gatacgtact ggggtcggga tttggagcaa acgtcctaga ttttcaatag ctccttgggt
    12001 cttctcgaca gatttctcta gcaggttaaa tttctgctcc agactaacac gtgcattttt
    12061 tatggctaga ttgaccagct gttttttctc tccacgttgg ggtttgagaa tcttggtatc
    12121 caccaaagcc ttgacagctt cttcgtcaat atcctgcgga atcagtacct cattgggaac
    12181 taggtgagat ttttcttgat agaattgtcc tacataggtc aaaaaatcct catctggatc
    12241 attgaagtag gggaagagat tgacatcgcg ctcgatgagc ttaccctgac ggacaaagaa
    12301 aacctgcaca cacatccagc ccttatccac atagtagcca aagacatcgc gattttggag
    12361 atccttagcc atgacccgtt gcttggttcg aagcgttcca atagcctgaa tcaggtcacg
    12421 gtattccgcc gcacgttcaa actccatagt ctgggctgcc gctgccattt tgccctttag
    12481 ctcatcaatg attttgttat cctgcccttt cagaaaatca gaaacctcct gggccataga
    12541 cttgaaataa gtctcatcct tcttacagat ggtgtgggcc atgcattgac cgatatggta
    12601 ataaaaacag accttagagg gcgggttggt acacttacga aaagggaata tccgatccag
    12661 caaccgcttg atttcattgg ctgcccccac atcgggatag ggtccaaaat aaagacctcc
    12721 gtcctttttg acctgacgag tgataatcaa gcgaggatac cgctcattag tgattttgat
    12781 gaagggatag gacttatcgt ccttgagcat aatattgtat ttaggcttat tttccttgat
    12841 tagattgatt tctaggagaa gtgcctcaat attggactcc gtaacaataa attcaaaatc
    12901 cacaatctca gacaccagag cctctgtttt ggtatcatga cttccacgga aataggaccg
    12961 cacgcggtta cgcagatttt tagcctttcc tacatagata atggtgccgt ttttatcctt
    13021 gtgaatgtaa caaccagggc tggtcggcaa gagctctagt tttgatttaa tcaagttatt
    13081 cataattcca ttatagcaaa aaagtaggga aagattgttc cctactcact agtctcatat
    13141 atttttcgga ggtttgtaac atcctcttcc tgaataccat aaaaggaacc tgcaggttgc
    13201 atcacagact tcccatctgt atggtccaag ccaatcgcat gccccaactc atgttctgcc
    13261 gtatggacaa ggcgctcata ggaatagcca tagtttggat tggacagata atagtgattc
    13321 aaccgtaccg tgacagacaa gaattgcccc gtcaagagat tggtctgact ttccgcctct
    13381 cctgccacag gagtgtttcc gttgttcatc tcagtagcca agatatccgc cgtgctggac
    13441 tcagtcacaa tttcaaagtt aaaagcacca gtttgattcc aattctggat tgcttctaca
    13501 taagcctctt gaaagcgtga atccatctgg ggatccaagt aaatacgagc agaagcctgt
    13561 gcccaccttc cttcagagtg ttggtgacta tctgtctggt tcaatttagg cagctgccct
    13621 gttctttccc attggtcaat actttgttga ccaatcttta ctgaccgttc tgcttgcttt
    13681 agcgctcctt gaaaatcccc gttcagatac cagagaaaac caaaagcaag agcgcataag
    13741 agaacaacta tccaaaccag gcgccaaaac aaacgccaca caaaagaaaa gaaagcccct
    13801 atcaaacgaa aaagccagcg catgtctctc cacctttcta gaaaataaaa actattttac
    13861 taaaacaagc tgaaagaaaa ctaaatactg actttttcat cttaacgtcc tactattttt
    13921 ttgagtaact ggatagcttt gtattttaaa ggcgatggat ggtaacggaa agtacctgct
    13981 ttgcgtacaa tatagccatt aaaattctgt ttaaaacgca aaacaccatc acttccatca
    14041 aaaatccctt gaatgcctag gaagttgtat ttaggtattc cacgttttat gctttccaac
    14101 ataacatatt tttgaagcag tgcaggggca tagaacttat taaactcagt gtaggaacca
    14161 ctaaagagat aagtcgtttc ctgaggcata taaacaaata aactcccagc taaaacaata
    14221 tcttcttctc catatttttc aatcaagtct cgcgcttctg cttttcgaac ttcaaacgtt
    14281 tcaaattgac tagaatattc tctcagttga ttttgttttt tctcagaatg aggattttta
    14341 ctcaaatcaa gtcgcaactt gtccaagttt tcttctagtt tactttgttc accttgcaat
    14401 ttgctcatat agtccgaaaa atttaagctt gctatgagaa actccgcttg ttctccaaaa
    14461 gtatcataaa aatgctcata atattctaaa cttttatcac tatattctct acgttcagag
    14521 gtttcttttg ttatattctt aaaaatcgat agttcttcac gttttaactt tttcaaccga
    14581 atgccaaagg tttcagcctt tttcaccaag ggtttaccct ttttgctaaa acttttaagc
    14641 aaactctttt cagttaattc agttaaatct ttatagtata accaatctgg ttctccacct
    14701 gggtaacctg ttgttaagcc atcaaattga taacctaaat cagtcaaacc ttgaataata
    14761 ctttttttct cagcatctat tgaattacct tggctatcaa aagtttgata agtttcataa
    14821 ggttttacaa gcaactctaa tacaccattt tgcttggcat attcttttaa ctctgcataa
    14881 aaaactggaa gagcatcttg ttgggtataa atcggccccg aattgagttc catatgcaga
    14941 ccacccagca tgggcaagct ataaaccaga gctgcaactt gaatttctcc ttcttgtttc
    15001 aaagcaagat aaacaattcg agcccctctt ttttctagca aatcccccat ctggacagat
    15061 tgcataaagg aacgagaaga aacctgatca gaataagtct gaaactcttc tttcgtgagt
    15121 gttgttagtg ccatatactt actttctatg tttttttctt aatgttttac ggaaatcaag
    15181 agcaagtctt aacagaggat agagaggatg agtgggcatt gtaaattcac ccaagtattc
    15241 ttcaatcgtt ggattaaatt tttccttaaa atgataaagt ccaccattga gagagttttc
    15301 aacaccacct aaattttgcc aaaccatacc tcgctcaaag gcatagcgag ccgtttcata
    15361 ccatgttaaa attggtgcat tgtaacgttt aaaatcatca tccataccag catatatatt
    15421 gacagaggta gtaccaaatt ccaaactcaa agtagccgct aaaggaactc tcgcttgacc
    15481 tacatctata tattcctgca agaaggtcaa ttcctctaac aaacgttctt tttccttctt
    15541 ctgcgcttct acttttgaaa ttcgagtcga ctcagtaaac gtctcttcca aggctctatt
    15601 tttcgctaac tgttcttcta attcttgcga acgtttagaa acatccaagg tggccaaggt
    15661 gatataggcc ttgtccttaa aattatctaa caatttttta taataggctt cattcctcaa
    15721 atgaatctct tttcgcttct cagttttttt catcaactcc gaaaatgaat ctaatagttc
    15781 cagtccacca tattgaatct caagcccttt gtttcgtgct gttcgaatag cctgttttgt
    15841 tgacttggaa agtttatctt cttcaaaatt ttccttgtat attttcgcct gaatacgagg
    15901 ttgaatggtg tctcccattt cctccgtttt tcctgaccac cttactccca tttgttgcaa
    15961 actatcaata atagccagat tttcaggaaa ttctgtcttt tcctgattga ttaaactttg
    16021 agataggcaa atacttgggt caaaagtcac aaaaaccgct ctcttactgc gagcatagga
    16081 cttaatagac tgaatgacaa aattcaagag ttctttatcc ccataatcca atataggtcc
    16141 tcttgggatg taaaacattt tatagcctag cggaagagtt ctaatcaaaa tactagctgt
    16201 cgccagtaat ttttcttccc tgtaaacacc aaacttctca tgttgccaat tagacttaac
    16261 ttcctcccaa gcactacttt gcaatacatt ggctaattca tgttctttga caaactgatc
    16321 atattctaat gtgggaatgc caatttgata acggtacatt tcctactctc tttcctccag
    16381 tattttatta ctattctact actttcgttt gaaaagtcta gtgaaaacat attttatttt
    16441 agttctactc cccctatgct gaagttcaaa ctaagtcagt ctctcttcta atttgaaatc
    16501 aattggtagg gttgttaaaa aaacttccaa ttgtttttcc cagtagtacc actcgtgagt
    16561 tccagcacta tggctatagg tcacatcaaa acctagtttt ttgagatttt tcactgcgag
    16621 attattggct tcgtacaaga aatcctgttc gccacaccac gcccaaagtt tggtcttttt
    16681 atccgatttt ttagccagac tttcaagaga atagggacta gttgtccagt ctctaatctc
    16741 tccaaaaaca cctctccagt aggctggact tcccagattt tgactttcag gagaaaagtt
    16801 ttgaaagctg agggcacctg aaaaactagc tgcatgagaa aaacgatttg tcgtaagagc
    16861 cagtttgaag cagccgtagc ctcccataga aagaccagcg ataaaggtct tttcacgctt
    16921 gctagtcata ttagggaaga agcgtttcag aacctgtggc aattcctctg ctagagccgt
    16981 gtagtagtca aaaccatact gggtatcggt gtaccaacca ttgctggtat tgggcataac
    17041 aacgatgaga ttagttcctc gaagcaagcg ttctacattg gtccgcttaa gccaactatt
    17101 atgatttcca gacatcccgt gcaaaaggta caagacggga atatcttcac actctggttc
    17161 ttccactcga ttggcatcag ggtagaggac attcaccccc cactccatat ccaatacttg
    17221 tgagtaatac tcgattttca ttactgccat gattttctcc ttctattttt ctataagaaa
    17281 aagccgaaac tcgactttct ctctgtttat ttcaacgatt attttgcttc catgactact
    17341 ggtaaaatag ctggacgacg cttggtttgg tcaaagagat acttggtcaa attatctcga
    17401 accttccctt taagatctgc ccagtcaaag tcatctcctt gaagataatc ttctaccgtt
    17461 tggttaatca attctgaact ttcacggaga atatcgcgac tcttcttgag ataaacaaat
    17521 ccgcgcgtat gaacacgagc cctagccaca attttcttct cacgacggtt gactgtaata
    17581 gccacgatga aaattccatc ctctgacaag accttacggt cacgaagaac aacatttcca
    17641 acatcaccaa tggcattccc atcaatcaag atatctcctg ctgaaaccga tccagctgga
    17701 acaaagtctc cattctcgta agccatggtc gtcccctttt taggaatgaa gatgcgttct
    17761 ggcaacatcc caactgccat ggcagcctta gcgtgagcat ccaactcacg atactcccct
    17821 tggacaggga agaggtactt aggttgcaaa agattaatca tcagctgcaa atcacgcaca
    17881 tttccgtgcc ctgatacatg taaactttgg gtaatcaatt tgacaacccc acctgcctga
    17941 taaatcatat tttctacacg cgcaacaaag gcttctttag caatagacgg agccgtagca
    18001 atatagacca ggtccccatc cttgatttct acataacgat ggcgaccaat cgacatctta
    18061 cgaagtccat tgataggttc acccatacga cctgtctcaa gaataatcaa ctcatggtct
    18121 tcaaagcgag acatatcttt aggcttaatc aagagaattt cgttggctaa agacaacttc
    18181 ttaagacgaa tcgctgtgcg gacgatattt tcaatatcaa atcctgtcaa gacgatacgt
    18241 cgacctgttt tatccgcagc gtcaaaaatc tgctgaatac gagaaagatt actggaaaca
    18301 gctgcaacga tgatacgacc ttcccagtca gcaatagttt gggtaatttc atccctaact
    18361 tcactttcac tagccacctg aatattgctg tctgcattgg ccgaatcact gaggagagcc
    18421 aggacgccgt cacgaccaat ctctgccaaa cgagcaaaat cagttgcata agattcacta
    18481 gccgtttggt caaatttgaa gtcacctgta taaacgatgc ttccttccga tgtcttcaag
    18541 acaattccca gactctctgg aacggagtaa gtcgtaggga agaaggaaac cactgtccca
    18601 ccaaaatcaa tctccgtatt ctcatcaatg acatggaaat cattaaattt cttaacggca
    18661 tcatttcctt tgacaaagag ctttgccaac tcaatggtca actcagaccc aaatacagga
    18721 actttagcct ctgccaagag ataaggtaga gcaccaatgg catccgcatg cccgtgggtc
    18781 aagaaaaccc cagcaatacg gtcgctattt tcaaaaaggt aatccatgtt tggaatcacc
    18841 acatcgaccc ctaattgttc attttcagga tattttaacc ctacattcaa aacaaaaatg
    18901 gactctccaa tttcagcaat gtacatattt tttccattct cacgcacacc accaagtgtt
    18961 gttaaactga tattactcat ttttcctcca aaatcttagt ttatcttgat tatagggcaa
    19021 ctctaccctc ttattctaaa agttctgata ctttcagccg aatcttttcc taccattata
    19081 ccattttttt gatgattttc aaaatgaagg tctgttttca aaaaagagtt gatttcccaa
    19141 ctctttccta acttctactc tttttccatc aaaaaatcat aaatttcttg caccgtaccc
    19201 agcgccatca tttcttggtc tttaacggtt tgtttgagat tttggtaaat ttgactttct
    19261 cctatctccc gctttggcgc ctctttattg actgtcatca caccatcttt tatcgtcaca
    19321 aagcctagtt cttcaaatac ttgaatcatc ttgaccagca agatttgttg aatattaaga
    19381 tatgcagcca aatctttcag cttgtagcga atatcaaact ctgggaaccg gtaaatagtc
    19441 ttgtacaatt tggcaaactg atctctagtc ccataacctg tcagataata ggccttgtca
    19501 atatcatttt tgaaatagac agcagagaaa tgctgttcct gaaaaatggt cttcagctga
    19561 gtaatatcct ctggaatgtt ttttacgaca acagcttcac tagccgcaag atttggcagt
    19621 tctccaggaa aatccaagac tggaacacct tctggcaaga ctgcattttt tccacgaatg
    19681 ttaaaaagtt gaacaccttc cactcgcgca tccaccatca tcaactggag ggcagtttgg
    19741 ccattccatt ggttgacaga caatttaacc gctaactcta gattcttggt ttgagaaaac
    19801 tctgtcgccc atctgccttg accaaaggct accacttcaa aactcgcctc acccttggaa
    19861 attttcagct ttagatgggc attacctgcc cccatagtac gagcactttc gacctgaaaa
    19921 ttcttgatat aaaaaatagg tttctgatta tccattccaa aaggagctaa acgttcaaaa
    19981 cttttgaccg tttccaagct aagtgcctcc aaatccaact cttcatctag gtttaactta
    20041 ttcttgccac cagcatctgc acctttttca cgaacataat cttccaaaac ctgagataaa
    20101 tctgagagtt gctcaacttc cagcgtcata cccgctgcac ctgcatgacc tccaaaggcg
    20161 atgaagaggt ctcgataggg atccagagct tcaaaaatat cgaccgcttc cacactacga
    20221 gcactgccct tggcacgacc gtcttctata ttaagaacaa tgactgtctg tcccaattct
    20281 tccaataaac gaccagccac gattcctaga accccaggat tccagccttc cttggccaag
    20341 acctgaacct tcttctcagg atccaccatg gtcttggctt cttcatagat agactgaacg
    20401 atttccttgc gctcttcgtt tttctggtga atcataaggg caatctcatg cgcttcctca
    20461 tcatcaaatc cagtcaacaa atcaatggca ggattgggat catccaagcg gcccaaggca
    20521 ttcaaacgag gagcaatctg gaaaccaacc gtttcttctg ttacttcgtt agcagcaatc
    20581 ccagccatgt ccagcatttc ttgcagacca atgcgctggg tatgacccaa catttccaga
    20641 ccatattgaa ctaagatacg attttcatcc gtcagactca ccatatctgc aatagttcca
    20701 atagcgacca aatcaagcaa ttccacttgc acttcttcta acagggcaca agccaacttg
    20761 aaagcaactc cacaaccagc caaatattta aaaggataat ccgcatctgg atgttcagga
    20821 tggacaatag cataagcatc tggcagggtt tcaggcatgg aatgatggtc tgtcacaatg
    20881 acatctactc ccatagactg agccaatgca atagcctcat gaccagcaac cccattgtcc
    20941 accgtcacaa tcaaggaaat cccttcttgc tcgataaagt atttataaac actagcatta
    21001 gggccatagc catcggtaaa acgatttggc aggtaaactc ggcactcagc accaagttgt
    21061 tccaaacttt ccttcacaat agaagccgaa gtcatgccat ccgcatcata gtctccataa
    21121 acgagaatat tttccccttc ttcaatagcc tgacgaatcc gctccactgc cttgtccata
    21181 tcatggagca gataagcatc atgtaagtcc tccaaggaag gttctaaaaa cttcttcaga
    21241 ctttcttggt tctgaatccc tctctcaaac aataaccgag ccacctcagg acccagtcca
    21301 gccttcttgg ctatctttgt aaaatccgca tcttctacct gcagggcaaa ctgccattca
    21361 taagtaggtg ttatcaaaaa gacatccact ctttctaaga attctattgc ttcattataa
    21421 catgatttag acgttttctc tatccagatt gcttttttat aacattttat agtatattga
    21481 aactagaata gtacacctct acttctaaaa tattgttaga aatcgatttg actgtcccga
    21541 tcgatttttc ctgttcttat ttcactatag tgaatttttt cagatatggt ttgacaagaa
    21601 cattctttta ttgtagaatc atgtcataaa atctaacaca agggagagct ctcatggctt
    21661 tagtagaatt taaaaacgtc gaaaaatatt acggagacta ccatgcactc cgcgacatca
    21721 atctccgttt tgaaaaagga caagtcgttg tcctactcgg accatctggt tctgggaaat
    21781 ccactcttat ccgtaccatc aatggtttgg aggctgttga caaaggaagt ctcctagtca
    21841 atgggcacca agttgctggt gccagccaga aagatttggt acctcttcgc aaggaagtcg
    21901 gcatggtttt tcaacatttt aacctttatc cacacaaaac ggtgttagaa aacgtgacac
    21961 tttcgcccat taaagttcta ggaattgata aaaaagaagc tgaaaaaacc gcccaaaaat
    22021 atctggaatt tgtaaatatg tgggacaaga aagattccta tcccgccatg ctatctggtg
    22081 gacaaaaaca gcgaatcgcc atcgctcgtg gtcttgctat gcatccggaa ctcctcctct
    22141 ttgatgaacc aacatctgct cttgatcctg agactatcgg agatgttcta gcagttatgc
    22201 agaaactggc gcatgatggg atgaacatga tcatcgttac ccacgaaatg ggctttgctc
    22261 gagaggttgc ggaccgcatt atctttatgg ccgacggaga agttttagta gatatgacag
    22321 atgtcgataa cttttttgac aatccaagcg aacctcgtgc ccaacaattc ctcagcaaaa
    22381 ttatcaacca cgaaagtgac aaagtcaaat aaggaggcgc ctatgaaaaa aaattctttt
    22441 tatcagcatt attgattagc cttttcggcc ttgctgctgc caaaccagtc caggctgata
    22501 ctagtatcgc agacattcaa aaaagaggcg aactggttgt cggtgtcaaa caagacgttc
    22561 ccaattttgg ttacaaagat cccaagaccg gtacttattc tggtatcgaa accgacttgg
    22621 ccaagatggt agctgatgaa ctcaaggtca agattcgcta tgtgccggtt acagcacaaa
    22681 cccgcggccc ccttctagac aatgaacagg tcgatatgga tatcgcgacc tttaccatca
    22741 cggacgaacg caaaaaactc tacaacttta ccagtcccta ctacacagac gcttctggat
    22801 ttttggtcaa taaatctgcc aaaatcaaaa agattgagga cctaaacggc aaaaccatcg
    22861 gagtcgccca aggttctatc acccaacgcc taattactga actgggtaaa aagaaaggtc
    22921 tgaagtttaa attcgtcgaa cttggttcct acccagaatt gattacttcc cttcacgctc
    22981 atcgtatcga tgccttttcc gttgaccgct ctattctgtc tggctacact agtaaacgca
    23041 cagaactact agatgatagt ttcaagccat ctgactacgg tattgttacc aagaaatcaa
    23101 atacagagct caacgactat cttgataact tggttactaa atggagcaag gatggtagtt
    23161 tgcagaaact ttatgaccgt tacaagctca aaccatctag ccatactgca gattaaggag
    23221 gacaccccat gacagattta tcatcttgga cagcctattt tcaggatttt ggacaatttt
    23281 tcaatggttt cctctttact cttgccctag cgattggatc ctttatcctc gccatggtct
    23341 taggaatctt ctttggtgcc atgtcaacca gtaaacgtcc aattttacgc attttagctc
    23401 acatctttgt ggaattttac caaaacactc ccctcttggt gcagtttgtt attgtttttt
    23461 atggcctacc tcttatcagt gaccatacta tcatgattcc aatttattgg acagctgttc
    23521 tctgcgtggg actctatcac ggcgcttata tcgctgaggt tattcgttca gggattcagt
    23581 ctattcctag tggtcagatg gaggccgcct tgtcgcaagg ttttacctat atcagtgcca
    23641 tgcgcttgat tatcttgcct cagaccttcc gcatcattct ccctccattg accaaccaaa
    23701 ttgttaacct catcaagaac acctctactg tagctatcat ctctggagta gacttgatgt
    23761 ttgtgactaa gtcttggtcg gctctcaacg gaaactatat cccagccttt ttaggtgctg
    23821 ctcttctcta ctttgctcta tgcttccctg ttgcccagtt tggtcgcaag atggagcaag
    23881 ccaacaaaaa agcctattca ctttaggagg ttactatgga atctatttta gaagttttaa
    23941 ccccagataa cctagtcttt atctttaaag gatttggctt gaccctctat atttctctga
    24001 ttgccatcat cctctctact atcatcggta cggtgctagc tgtcatgaga aatggcaaaa
    24061 atcctgtctt acgcattatt tccagtattt atatcgagtt tgtgcgcaac gttcccaacc
    24121 ttctctggat ttttactatc tttttggtgt tcaaaatgaa atccacacca gcaggtatta
    24181 cagcctttac tctctttaca tcagcagcct tggctgagat tattcgaggc ggtctcaatg
    24241 ccgtagacaa gggacagtac gaagcaggaa tgtcacaagg cttcacctca gcccaaatcc
    24301 tctactacat cattctccca caagccatcc gcaaaatgct accagccatc atttctcagt
    24361 ttgttaccgt gattaaggat accagtctcc tctactctgt tatcgcccta caagaactct
    24421 ttggagccag ccaaattctc atgggccgtt atttcgaacc agagcaggtc ttcagtcttt
    24481 gcatcctgat tgccctcatc tacttcagct ttaacctagc aatttctagc ctgtctcata
    24541 tgctagccaa acgttggcaa caagctgcag aataatactc ttcgaaaatc tcttcaaacc
    24601 acgtcagctt caccttgccg tatatatgtt actgacttcg tcagttctat ccacaacctc
    24661 aaaacggtgt tttgagcagc ctgcggctag cttcctagtt tgctctttga ttttcattaa
    24721 gtataaacag ccactctcca gttcaattgg agagtttttt gatgagagta gatatttata
    24781 gacctcaatt tgacaccata cattttctat gataaaatgt aacaaattca tttacaacaa
    24841 atcgaaatct aaatgaaatg gaattttcta tgaaatcagt caaaggacta ctctttatca
    24901 tagctagttt tatcttgact cttttgactt ggatgaacac ttctccccaa ttcatgattc
    24961 caggactagc tttaacaagc ctatctctga cttttatcct agccactcgt ctcccactac
    25021 tagaaagctg gtttcacggt ttggagaagg tctacaccgt ccacaaattc acagcctttc
    25081 tctccatcat cctactaatc tttcataact ttagtatggg cggtttgtgg ggctctcgct
    25141 tagctgctca gtttggcaat cttgccatct atatctttgc cagcatcatc cttgtcgcct
    25201 atttaggcaa atacatccaa tacgaagctt ggcgatggat tcaccgcctg gtttacctag
    25261 cctatatttt aggactcttt cacatctaca tgataatggg caatcgtctc cttacattta
    25321 atcttctaag ttttcttgtt ggtagctatg cccttttagg cttactagct ggtttttata
    25381 tcatttttct atatcaaaag atttccttcc cctatctagg gaaaattacc catctcaaac
    25441 gcttaaatca cgatactaga gaaattcaaa tccatcttag cagacctttc aactatcaat
    25501 caggacaatt tgcctttcta aagattttcc aagaaggctt tgaaagtgct ccgcatccct
    25561 tttctatctc aggaggtcat ggtcaaactc tttactttac tgttaaaaat tcaggcgacc
    25621 ataccaagaa tatctatgat aatcttcaag ccggcagcaa agtaacccta gacagagctt
    25681 acggacacat gatcatagaa gaaggacgag aaaatcaggt ttggattgct ggaggtattg
    25741 ggatcacccc cttcatctct tacatccgtg aacatcctat tttagataaa caggttcact
    25801 tctactatag cttccgtgga gatgaaaatg cagtctacct agatttactc cgtaactatg
    25861 ctcagaaaaa tcctaatttt gaactccatc taatcgacag tacgaaagac ggctatctta
    25921 attttgaaca aaaagaagtg cccgaacatg caaccgtcta tatgtgtggt cctatttcta
    25981 tgatgaaggc acttgccaaa cagattaaga aacaaaatcc aaaaacagag cttatttacg
    26041 aaggattcaa gttcaaataa gtaatcatac tctcctggaa tttcccagga gagtttttta
    26101 tagccaaatg aaataagacc ggaacgatgg aattttggca ttcaaatcaa ttgataagaa
    26161 tattttatag tggagtgaaa taggatacga acaaattgat taggaaaatc aaatgaattt
    26221 atagaaatct tttagcagtt atgttatcct attctagttt caaaacgcta tagaagtagc
    26281 attgtgctag tctagattca gtttactata ctaaaacgag tagcttgaaa tcaaaaaacc
    26341 caccctcaca ggcaggtttt atctgtatta ttcagctaga ttatgcttta ccttctgaac
    26401 cgaatacgtc gatacgttct tcaaccgatg cttggatagc ttttacaccg tcagccaaga
    26461 atttacgtgg gtcgaagagt tttttcttat cgtattctgc ttcgtttgct tcgtagtcac
    26521 gagcaaattt acgagttgcg ttagcgaatg cgatttggca ttctgtgtta acgttaactt
    26581 tggcaacacc aagtttgata gctgcttgga tttgctcatc aggaatacct gatccaccgt
    26641 gcaatacgat tgggaatcct ggaagagctt ctgtcaattt ttgcaagtgg tcaaggtcaa
    26701 gaccttccca gtttactggg taaggaccgt ggatgttacc gataccagct gccaagaagt
    26761 cgataccagt ttcaaccatt gctttagcgt cttcgattgg agccaattca cctttaccga
    26821 tgattccgtc ttcttcacca ccgatagtac caacttcagc ttctactgag atacctttag
    26881 cgtgtgcttt ttcaacaact tctttagcca atttaaggtt ttcttcaact ggaaggtgtg
    26941 aaccgtcaaa catgattgaa gtataaccaa cttcaataca ctcaagtgca tcttcgtagt
    27001 gaccgtggtc aaggtggata gctactggta cagtgatacc cattgattca acaaggttag
    27061 cgatcaagtt gcgagcaact ttgtaaccac ccatgtattt agcagcaccc attgaagttt
    27121 ggatcaaaac tggagctttt ttagcttctg ctgcgcgcaa gatagcttga gtccactcaa
    27181 ggttgtttgt gttaaatcca ccaactgcat aaccgttgtc acgggctgct tggacaaatt
    27241 tttctgctga aacgattgcc attttatcag gcctcctgta tatttttatg ggtcatccca
    27301 tttacattgt tcattttatc actttttgcc aaaaaaatct agtttttccc gcagtttcga
    27361 ttgattttct tctaactcca tctatgtaaa ccctttctct ccctagtctt gggcgacttt
    27421 tggaaaagct ataaagaagg ttaaacgatt ctcctccatc tcgaaacgat aagctaattt
    27481 ttcatgttct aatagactct taaccacaaa gagccccata ccagacccct tgaccttgcg
    27541 actagcattg tcagaaaaag actgggctag tttttcttgt tcctctgagc tacagctatt
    27601 ttcgataaaa agttctcctt ctctttctcc aattcgaact aagccacctg gaacagagtg
    27661 cttaatggca ttgctgatga gattagaaag aatcaacttc ataactgatg ggtttagata
    27721 agcctgctga tgggtcaaac tattgtctat ctggagctct ctttccttag ctagcaaggc
    27781 ataatctttg accagatttt gcgtcatctg gaggaggtca attgtttccc tatcatctcg
    27841 caattcctgc acagaagaga gggaaagtat ctgcagaaca tggtgattga gttcatccac
    27901 aatccccaag gcaactccca gatactggtc tctatcctta taacgaccga tattctctct
    27961 catattttcg attaggattt tcaaactagc cagcggtgtt ttcaattcat gagaagctcc
    28021 tcgtaggaat tcgaccttca tcttctccag ctggagaatg gcttcattct tttcatgcaa
    28081 gtccgcaata acagtcaaga gatgctggta gaggctattg atttgttcct tgagattacc
    28141 tatctcatcc ttagaatcca cgcgcaatcg cacttgggaa tccaggtcca tcatccgacg
    28201 ggtcacccgc ttgatttcca agatcggtgc aacaatagtc cgagcgtaga tgtaggccac
    28261 caagagggaa atcagaaagg aggccagcaa ggtataggga agaaactgga gactgatttg
    28321 ctccgcttcc ttttgtaaat ccatggaagc tagaaactgg agaatcatag tagcaccgtc
    28381 ttgcgttttc acctcgcgct cctcaataaa gagagaggtt gtctggcggt ctgtgtccag
    28441 aggaagactg tccttgactt ctaacttgtc ctcggtcatc tcacctttga cggtcccctt
    28501 gatatcacta gtctgggaat acaagtctaa cacttgctcg atactctgcc tatctttccc
    28561 ttctagggac tgggcaatgg ctgttgcctt ttgaccaatg gtttcctgac gatgactcag
    28621 ataagtcgaa ggaaaaagaa aataaatagc taaatgaagg cagataacca gaacactaaa
    28681 tatcgagaag gtatagataa atatctttgc aaataaacct gttcgtttca ttttcgctcc
    28741 aatttataac caacattgcg cacagtgagg atacaatcca agtctagctt tttccgcaat
    28801 tccttgatat aaacatcaat aacacggtca aagggaacct catctgtcgc tttccagacg
    28861 gcatcgataa tctgagatcg agtcaaggcc cggccttcat ttttcactag atagtccaga
    28921 atttccaact ctttggcatt gataggcact tcttgacctg cgatgcttgc actgtagctt
    28981 tcaaagtcca ccttggtatc cttgtaagaa aagattcgtc ctgtatcgta gtagcgcttg
    29041 aaaatcgcgt ccaccctcac ttttaaaagg gagagggaga aaggtttttc cagatagcca
    29101 tctgccaaag aggcaaaggc actcatcttg tattcctcat cctgaaaagc tgtcaacatc
    29161 aagacaggaa cctgactggt tttacgaatc tcagctagga cttctaagcc gttgagcttg
    29221 ggcatctgga tatccagtaa aaccagggcc acctcatagc tagaaaattg ctccagagct
    29281 tcctgaccgt ccgctgcctc aatagtttca tagccacaat ccgtcaaata atcactgacc
    29341 ccctcacgga tcatctcttc atcttctaca attaaaattt tcatacttta actgctctct
    29401 attttttatt tttcttagaa taaataccta ctctattttc tattatagtc tcttgctggc
    29461 cttttgtctg taagcaactg accactagat aaaacgttgt gaaatccttt ctcataaatt
    29521 ccataacttt agtatattat atttaagcac taaagtacaa agaaagcaac tgaaagcaat
    29581 gattttcacc actgctttcg gatttatttt gaattgttaa atagccattc ctatccacta
    29641 ttcttgaata gaaacacaag atgcaatctt tattccagac tcattttttc aaatttattc
    29701 accatccagc aagagctctt ttggttgttt tctaaggaga ttgcttgaag caagcgccat
    29761 aacgagaacc actagaacca aggcaaggac aaaaatgatg ataaagtctg atgtctgaat
    29821 agaaatgtct aggctcgaca aggtcttgct aaagccatct acttctgcac caccaccaag
    29881 gttagaggct tgagccgcct tactagcctg tttggcaaca cctgaagtca cattggcaag
    29941 gacagtgttt ccaattgcac gggcagtgta attagctagg aagtaagcag aaactagagc
    30001 agggatagca atcaagatag attcggtgat gaattgaccc aagatacttg cctgcttgag
    30061 gccgatagag aggagaattc ccacttcctt gcgacgggcg ttgatccaaa ggctgagcaa
    30121 gagggcaagg aggagaactg agaagctcaa gctaccccag aagaggaggt tggccatctt
    30181 gtacatacca gagatagatt gctcaagagc tgggtagtta gaggagctct tgacgagtgt
    30241 gtagctcttc cagttgatac cactgatgcc attcaactct ttcataacat catccaagtt
    30301 cttgtctgct gttacaaaga aggttgcgtc cccataaatg gctgtgtctt ctgtgtatcc
    30361 ataaagtttt gcagcagtgt gaatgtctgt aatagctgtg ttttcgtaaa gttcttgtga
    30421 gtaggttact gctgacttat tatgaccatc aaagagtccc ttgattgtca cttcaactgt
    30481 ttccttggct cctttttcat tatctgcatc gtagatatta gagtccagtt taaccttgtc
    30541 ccctactttc cagccgtgtt tggctgccaa gtccttgtgc aagaggattt tatccttgtc
    30601 gtcgttggtt aagtgctctc cttcgactag tttataagaa ccagagacaa acttgtcttc
    30661 tttagaggag tcattgacac ctgtaatcat caagctactt ccaaaacgtt tggcacgatc
    30721 agcagtgaga ttcttcttgg tttctggcgt ttcaatcagg tcatatccag tcaaatctcc
    30781 gatagcgttg atacgtttga cataagactc aatggccttg ttttcggtga tttttttgat
    30841 gtcttcaccc ttgatattcc cagcaccgcg aggcgttcct tggttgacgc gacgattgat
    30901 ttgcatggag aagctattgg tgatattttt aaaggtctcc tgagaagcct tggcagtagc
    30961 tcccttgatt gacaagccga ccaaactcaa gctcgccatg aggagaataa tcaggaagat
    31021 gacaatcgat ttgaaaaact tccttgtaac ataggcaaat gcgttgtgta acatagattc
    31081 cctttctaga ttttgtttta atcattctat taaagtaagc tcaaattatt tactagtatt
    31141 gcgcgtttca gtcagtttct tatcctttaa ttcaagtgta atatctgacg cttgtgccac
    31201 ttctttactg tgagttacga caatcacaca tttacctgtt ttctgggcaa gtgatttgag
    31261 tagttcgaca atatctccag cagttttagg atccagattt cctgttggct catcagctag
    31321 aataactgga gcttctgaga ccaaactgcg agcaatggca acacgttgct gttgaccacc
    31381 tgataactgg agaacattcc gcttgatctg actttcatcc aaaccaagct caagaagtgt
    31441 atccttgctt gcctttttgt tgaccaattg gatattttcc agcggagaaa gataatctat
    31501 caagttataa ttttgaaaga ccagggaaat atggtgcatg cgatggtaag aatagccctt
    31561 cttacgaata tcctctcctt gaaaaaggat agaaccttca acaggactat ctagaccagc
    31621 aagtagggac aagagtgtgg attttcctgc tcctgactcc ccaataatac tgtaaaattt
    31681 tccgggttca aaattataat tgatctgata taggactgct tcagcagtat tcttataacg
    31741 gtaggtaaca tcttgtaatt gtaataaagt catgatttct ccttcttaac taatagatga
    31801 taaaatttct ttcggtgatt ttctaaataa gaataggaaa caaagggcta cagataagca
    31861 actaagcaga actagaaaaa cataggattc tgcaaaagat aagatactag ttgataaact
    31921 gcttgctttg gctagtgtat cttgtaagct tgcctgatct ccacttgcta gtagagtttg
    31981 gagtaggtaa gttgtgattc cgtttcctgc aacaaatgct ggaagcaaag ctccaagaga
    32041 taccaaaact acctctaaac agaattgtag gaagatcgag ctcttgcctt ttccaagtgc
    32101 aagtaaaatc cccacttcat agacccgttc tctcaaccag agagacaaaa ccagaattaa
    32161 ggctccagct cctgctatca acatcccata aaggaagatg gtcaggaagg tttggaaagt
    32221 tgcaactgag tctttgattt gttcaaaagc cttgttttcc ttttcgactt ggtagccttg
    32281 attttccaag gccaagtttt ctacctgctt catgagtccg tccatttcct taggattttc
    32341 tacatagaag cgtgctgcac tgacttgagc ttcactattg cccaaaaggg tttggctact
    32401 ttcatagtct gtaaagactt gattttcact gaagtcagaa gacaagcctg tgaatttctc
    32461 ttgtttttta ccagaaaaga tgccaataat ctcaaactct actgtttgtc cttttccaga
    32521 ttcagactga ccagcatcca agccaatctt gtcatgaagt gaaagaccgt tcttcttagc
    32581 caattcttcg tggataagga ttttcttgga atcccctttt tgaaggtgtc gcccttcttt
    32641 tagattgaaa gccgaactgg taaaggttac atccttggat gaatcctcaa gagccgttaa
    32701 gctaaccaag ttattgtctg cagctgataa atcatcacgc tccacgctct gctcgccagt
    32761 cactgcttcc ttgtctttta gttttgcgac catctcaagt tcaggagaga cattttccag
    32821 ccccttaatc ttgcttacag atgctaggtc tgacaacttg aatgtctgac cattctctat
    32881 cttcttaata gaaaaagatg tattgagtga tttataaaga ttgctttcta ctgttttgtt
    32941 ggacttcatc agagtcaaac aggctgaaat tccggccaat aagaccaata aaatcagaaa
    33001 taaaataaaa cttctcagtc gctttctgct gacataagcc caagatcttt ggattggatt
    33061 catttgtcac ctccatattt gtaagactat tataaaaccc aaatatgaaa tgtttatgaa
    33121 atacgaaaaa aaatatcgag taggggataa tctctcgccc ctctcacacc accgtacgtg
    33181 ccgttcggca tacggcggtt caactaactt ttaacgcatg tcgttcaagg taataatcca
    33241 aacacgaaac ctgttcacgt ttttcaagga ctggttttga tatagcacgt ttaagtaccg
    33301 acttctgagc tactatagta gattgaaact agaatagtac atctcttctt ctaaaacatt
    33361 gttagaaatc gatttgactt ccctgatcga ttcgtcctat tcttatttca ttttaatata
    33421 attgatagtg gtcgccccag ccagatacct tatctgctat ccatttagga acccctaact
    33481 taagcaatcc ccataatcgt ctcgatttct tcttccattg cttccagata atcactcgta
    33541 ggcgagtacg caagcgctca tctatgctag tgactatact tttcatattt ataattcatt
    33601 cctttcgttt cactcaaggc acaacacaga atgaaaaagt gttgtgatct ttattttgtt
    33661 ttataataat agtgagaaag cctatcacta ctacaaatca cgaggaggtg aataagtgag
    33721 tggtacagcc actacctcgc atattttgtc acatcattta acggtacata ataagttgta
    33781 ccatctgaat aagttgctac aatatcattt gcatgctctc cttcaccttt agcaaaggtt
    33841 ggagctcctg ctggatgatt tttatttgcc tctttcaatt tttcaataat ggcatttttt
    33901 tctgtatctt ttatattatc aggatttttc actaagattt tgtctggata tgtcggttta
    33961 gcagaaacaa tttttactgt tatttctttt ttattcgaag cacttgtcca gtttccagca
    34021 ttatctttag tatttaattt tacagtaatt cctgaactag gaacttcagt agcaggttga
    34081 ttatcaacat tattcaactt taatttcaaa agagctgttg catcagacgt tttatcaatc
    34141 gttatatata atgataaatt gttattataa ccagtttctt catatttagc tgtttgtgag
    34201 ctacttgaaa cagaactgaa attatgccca ctacctccct gattatcttc aatgcttacg
    34261 tctaaatgaa cttccccact attatttggc ttagcaacaa ctgttatagt aaaataacat
    34321 aaaatttgca taaatagatt agggaaatca aagcaacttc taggaatgtt ttagcagtca
    34381 cagtgtactt tcccagcatc aatccactat aactctgcac ataaaaatgg agaagatggc
    34441 catcctcttc tccaaatatt aacttcttta caaaccaact atagttgaca aagaacctaa
    34501 aatcaattga taacacaagg tcaggtcggt caactctttc aactgaagcc ctgtcaactc
    34561 ttcccattta tcaatcttgt attggagaga attgcggtgc agatagagtt gctgggctgt
    34621 tttagtgaga acagcactat tttcccaaag agagagaatg atttcctgaa tctgatcttg
    34681 atccaaaatc atctggtgta gacattcttt aattggcttc aagtccacga gtctttctcc
    34741 catactccaa agatagagct gagaaaaagt atgaacacct tggtgaccct gacgccacca
    34801 tgtcttgaac aaatcccgct cagctttgat taagtctgat agggcttgat gtcctgtctg
    34861 agaccaaacc tgacccaaca tgatagaaag acgaagtcca aagtcatact caaccgcttc
    34921 aatcgtatca cttaaaatat ctcttacaga agtgtatttg tcttgttgaa gcacgaaaac
    34981 ataatcctga gatccgacct gtagcactgt ctgacaattc ggaaaaagag tccgcatcat
    35041 atctagccaa gaagccagat tttcctgctg aaaataagaa agatggcaat aaaccaactg
    35101 aatcttttta aaaacttgcg gtgcctgtcc cttgccttca accagatagg aataccaagg
    35161 gtttagcgaa cgagcctgct cctgctgggt caaaagggca accaactgct tttcacgctc
    35221 gctgagccca gcttcctcca gcaaaatcca ctgctgagaa gctaaaggga gcgtgagata
    35281 gccctctttc tctactggtt ggtctgaaat ccgagcctca ggaaaccagt cttgtagttc
    35341 tttttccctc atgttctagc cctccacttt ttggatgcac catgaaacca aactctcaag
    35401 acgttccaga ttctcagtca tatggagata gcccataacc gcttcaaatc ccgtggacat
    35461 acgataagtc acgacatctg catttttagc ctttgtgtgg ctattggtat tgcggccacg
    35521 tttgtagatt tcttcttctt tttccgttag gacctgctcc tccaacatga gagcaatcag
    35581 gcgagcctga gccttggctg acacatactt ggttgcttct tgatggagtt tattgggttt
    35641 ggtcatacct ttgaggatga ggtgacggcg aatatacata gaatacaccg catccccctc
    35701 aaaggctagc gcaatcccgt taatgagatt gacatcaatc acgtgtccac ctcactccat
    35761 ccttggtatc aaggagctta attccttgag taaccaattg gtcacggatt tggtctgctg
    35821 tctcaaagtc tcgattggca cgcgcctctt ggcgtttttg aatcaagtct tcaatctctg
    35881 catccaaaac ttcctcaaca aagacaattc caaaaatttc taacatatct gcaagagctt
    35941 gcttgacact tgcatcatag ttccctgagt tgatccattt ggccatttca aagacaactg
    36001 tgataccgtt ggcagcatta aaatcttcat ccatagctgc tacaaactta tctttaaagt
    36061 tttgtaactc ttgggcatcc acgtttcctg taaatggttg ttcgtaagta ttcttcagat
    36121 acttgagatt ggtctcggca tcgcgaactg ccttttccgt gaagttgata ggcttacggt
    36181 agtgctgggt cgcaaagaag aaacgaagta cttgcccatc aagagtttta agggcatcgt
    36241 gtaccgtaat gaagttaccc aaggacttag acattttgac attgtcgata ttgacaaagc
    36301 cattgtgcat ccagtagtta gcaaaagcct tgcctgtttt agcttcagat tgggcaattt
    36361 cattggtgtg gtgtggaaac tctaggtcag ctccaccacc gtggatatca atggtatcac
    36421 ctaaaatctc tgtcgacatg actgaacact caatatgcca acccggacgt ccaggtcccc
    36481 aaggactatc ccaagaaatc tcacctggtt tggaagattt ccatagagca aaatctacag
    36541 gattttcctt acgagccgtt tcttcatcgg tacgacctga agcacctagc tccaaatctt
    36601 ccaaggtttt attagccaat ttagcatagt tgtgggattt ttctacacgg aaatagacat
    36661 ccccttgact ctcataggca aagcctttct cgatcaagtc ttccacaaaa cggatgatgt
    36721 ctgccataaa ctccactaca cgcggatggc gagtcgcagg tttcacgcct aaggccgtca
    36781 catcctcacg aaaggcagcg atgtacttat ccgcaacctc ctgaggtgtg atgccttctt
    36841 ccctggcacg gttgataatc ttatcatcca catctgtaaa attggaaata taggcaacct
    36901 tatacccacg gtactcaaaa tagcgacgaa tcgtatcaaa agctaccgtc gaacgggcgt
    36961 ttcccacgtg aatatagttg tacacggttg gcccacaaac atacatcttg atcttgccgt
    37021 cctcaatcgg gacaaattct cgcaaatcac gagacatggt gtcatagatt ttaatcataa
    37081 atcataatca agaaagctaa aatccaagaa ctgttagttt catcactaaa ctaagagctc
    37141 aagtaaattt cagtccgaat gtctctacac ttcggaatcc cttgctcctt tctcattcag
    37201 ataaaccacc tgtgtctgtt tgacaaagcc aattttttca tacaaacgtt tggcacctac
    37261 attgctatct tccactgcaa tctgaaattc cttatcattt tgctcaatta gttggttgac
    37321 aagggatttt gctaagtagc ttccatagcc ttttccacgt tcaggttctg atattgctaa
    37381 accgtagaag taattcgtat cgctcgataa atcaaccgtg caagtcccaa taacctgacc
    37441 gtcttttaac aaaatatata agcgactttc tggatccttc agagcttcag cgacatatct
    37501 atccacaact tctctcgatt catgttcccc tgaaaatgcc tgaaatttta actggctaat
    37561 ttgctcctga tacgaactat ctgctaacaa aacttcaaga ttagaaagtt ttgctaactg
    37621 atatggtctt ctatccttac ctaaccaggt ttctgtctct tcatcctcga ttagtcccca
    37681 gttactggca aagtcaggat gattctctaa aaaaatacgt tctgtctgaa aagtgactga
    37741 ccgaatgggg aaagaagctg tttctctctc aaaactagta aacaatgcac gcgcaatccc
    37801 ctgacggcga tgacctggat gaaccagtat cgtcacttct acatcttggt catctgcata
    37861 gacagttaat aaaccaacaa gtttgccttt ttcataataa aggaaaaagg cgggcatgtt
    37921 tgggtcaaaa ttaagcatgt tagagagata gggatcgcga taggtaccgt catagttttg
    37981 gcaacagtta attacttttt tcgcctcaga tagctcctct tggcttaact tgtttcttgc
    38041 ttgaatcata taggtatcct ctacaaacca gacgatctgt gactggcatc tttagcctgc
    38101 tcgagtttat tgacataata ctcccgtttt tcttcgactt cgtgaataac aggctcatct
    38161 ttcttaccat gaagacggac aatcttggcc ggaataccga caaccgtcac atcactaggt
    38221 acatctgcta cgacaactgc tgcagcaccg accttggcat tttcaccaat ttccacaggc
    38281 ccgataactt gggcatgggc tgatatgagg gctccctttc gtacagtcgg atggcgtttg
    38341 ccacagtctt tccctgttcc cccgagagtc actccgtgat agagaagaac gcctttttca
    38401 acaatcgctg tctctccaat caccagacca gaaccatggt caataaagac acctgaatca
    38461 atctgggctc ctggatgaat ctcaatctga gtccaaaagc gccaaaactg actgtgcata
    38521 cgagctaaga gtttgaagtc gtacttccag agaaaatgcg agagacggtg ggccgccaag
    38581 gccttgacac ctggataagt cagcaaaacc tccaaagtgg tgcgggccgc tggatcattt
    38641 tcttttacga tatcaatggt ttcgtgccac caccccatac atttctcctt ttcttactct
    38701 gaatcttttg gtgtttctgt aaattctttc ttaggtttgt gatccttgtg atgacgtggg
    38761 cggtgagggc gctcagactt ttcacctttt tcatcatgct caggttttgg cggacgaggt
    38821 agaagagcct tcatagaggc atcgatacgg cctttttcat caatcttgat aaccttaaca
    38881 tcaacttcat ccccgatttc taccaaatcc tctacacgat tggtacgagt ccaagccatc
    38941 tcagagatat gaacaagggc atctgtctta tcaaagaggt taacaaaggc accaaatttc
    39001 tcgatacgaa cgactttagc acggtaaact tcatccactt tggcttcacg aaccaaacca
    39061 gcaataattt ctttggcacg gttaatagca tcttggtcac tagagtagat agacacattt
    39121 ccttcttcgt ctatatcaat cttaacacct gtttcagcga taatcttgtc gatggtttct
    39181 ccacccttac cgatgacaat cttaatcttg tccacatcaa tcttgatcgt atcaattttc
    39241 ggagcagttg gagccaattc tggacgaact tctggaatgg ttgcttcaat gacatcaagg
    39301 atttcaaaac gcgctttctt ggcttgagca agagcctccg tcaagatttc tgcagtaatc
    39361 ccttgaatct tgatatccat ttgaagggct gtaatcccat cacgagtacc tgcaaccttg
    39421 aagtccatat ctccaaagtg atcttccaaa ccttggatat ctgtcaatac tgtgtagtta
    39481 tttccatctg agataagtcc catagcaata ccagctactg gcgccttgat tggcacacca
    39541 ccagtcataa gggcaagagt tcccgcacag atagaagctt gagatgaaga accgtttgat
    39601 tccaaaactt ctgctactag acggatagcg tatgggaatt cttccaagct tggcaagact
    39661 tgagcaagag cacgctcacc aagggcaccg tgaccgattt cacgacgacc tggcgcaccg
    39721 taacgacctg tttcccctac agaatattga gggaagttat agtggtgcat aaagcgtttc
    39781 ttgtactctg gatccaaacc atcaatgatt tgagtttctc ccatcggagc caaggtcaag
    39841 actgaaagag cttgagtttg cccacgagta aagagacctg aaccatgtac acgaggaagg
    39901 aagtcaacaa ccgcatccaa aggacggatt tcatcgacct tacgaccatc aggacgcacc
    39961 ttgtcttctg taattaaacg tcgcacttct gcgtgttcca tttgttccaa gatttcagcc
    40021 acatcacgca taatacggtc aaattcttcg tggttcgcat atttttcttc gtaaacggca
    40081 gtcacttggt ctttcactac ttgagttgca gcttcacggg ccaatttctc ttctacttga
    40141 actgcctttt ggaggtcact gttgtaggct gcaatgattt cagcttgcaa ttcagcatcc
    40201 acgtgaagca attccacttc tgctttttct ttaccgacag cagcaacgat ttcttcttgg
    40261 aaggcaatca attctttgac agcttcgtgc cctttaagaa gcgcttccaa catgatttct
    40321 tctgacaatt ctttggcacc agactctacc atgttgatag cgtgcttggt tccagctact
    40381 gtcaattcaa gaagagattg ctctgcttgt tcttgacttg ggttgatgat gatttggcca
    40441 tctacatatc ccacttgtac cccagcaatt ggtccgtcaa atggaatatc tgaaatagac
    40501 agtgccaaag atgaaccaaa catagcagcc attggtgcag atgcattttc atcataagaa
    40561 agcactgtat tgatgacttg gacttcatta cggaaacctt ccgcaaacat aggacgaatc
    40621 ggacggtcaa tcaaacgcgc tgtcaaggtc gcatctgttg aaggacgtcc ttcacgtttc
    40681 ataaagccac caggaaactt cccagccgca tacatttttt cttcgtagtt gacttggagt
    40741 gggaagaaat ccccagttgc cattttctta gacataacgg cagcagtcaa gacagttgac
    40801 tcaccgtaac gtacgacaac agagccattt gcttgcttag caacctgacc agtttctaca
    40861 attaactcac gacccgcaaa agtcgtttga aacacttgtt ttgccatttt aatccccttt
    40921 ggattgatga aattatacgc cttgcctaca aagatcaaga taccaaggac gtcaaaagca
    40981 aagtaaaaat aggaaactga cgaagtcttc gatgaagaca agacagttta tcttttttac
    41041 acagcttttc ggccgtgttc aattacacaa gatattttgg acggttcggc ttgccgaaca
    41101 tttctgtaga aaaataggaa ggtgacgtcg cactcgacga gtgctaggaa gcttatcttt
    41161 tttcctaaga aatgagacca aaattcaatt actcaagata ctaagccgtc aagcaactca
    41221 aaggaaaata ggaaatcgaa cgacggagcg actgctccta gggagattta tctttttcca
    41281 cagagttgta ggcgagttca gttttcaaga tataaatcat tagaaaggtt taatactaaa
    41341 gtatctaaag ctttcacgct aatcgctatc gggcgattag ttaaatgctt tactaactct
    41401 ctcgtcaaat aacatcgatt tgactcactc gtgtcgttaa atcttacagt ttaaatgcat
    41461 tgtattattt aataccttca tctttgtatc aagtacgtac agaatttatt ttatcatatt
    41521 tttcttaaaa agtgaggtct ttaccattaa aaaggaacca ttcccctcac ctgagaagaa
    41581 tggtttgctt ttattatcct agagactggt gattaaacaa ggcatgggtt gcttgatgga
    41641 tgtattttgc tgtatcagca ttattcatcg tatagagatg cacaccggca acatcctgag
    41701 ttaccaagtc cacgatttgg tccactgcat aggcaagtcc tgctgctctg agcgactcag
    41761 ggtcatgctc atacttgtct aagatggctt taaatttgcg tggaagatgg atattctcac
    41821 aagtcttcaa gagtcggaga gcctgatttc gattcagaat tggcataatt cctgcatgaa
    41881 tgggaacatc aatcccagcc aagatgcact tgtcctgaaa atcatagaag cgctcattgt
    41941 caaagaagag ctgagttacg aggctcgaac agcctgcatc cactttcttc ttaagatttt
    42001 gaatatctga aatctgattt ggcgaatctg gatgcccttc tggatagcaa gctccaataa
    42061 tatcaaagtg aggggtttgt tccttgataa actcaatcaa gtctgttgca tagcggaaat
    42121 ccttttgtgg ttccacgtct ggaataatat ccccacgaag agccaagatt ttctgcaccc
    42181 caactttgtc caagtcagca atagtttcag caaccttgtc cttagttaga taaatagctg
    42241 gcaagtgggc aatggtcgga atcgccaaat cattttggat aaagtcagcc aaacgaaccg
    42301 tcgtttcctt gatattaaat ttattattgc tggcagttac actgataaaa tggggagcca
    42361 actcctgcat atcctgcaag gctgaaataa tgttatcatt acccacggct gggtttggag
    42421 ggaacacttc aaatgagagt gacggtgttt ggcgtgacat atgtaataac cttttctagt
    42481 tgatttcttt ttgaacaacc actgtatgga gagaaatcca atcttacaat ttctcacgcg
    42541 cagctttagc tgcttcaaca aggcggatca agctttcttt tgtttctggg ataccacgtg
    42601 ttttcaaacc acagtcaggg ttgatccaaa ctttcttgct tggcacttta gcaaggatga
    42661 cttcgattgt gttgtcgatt tcgccttcat ttggtacacg aggtgagtgg atatcgtaaa
    42721 ccccaggtcc cacttctgtt tggaagtttt tcgctttgag ttcgtccaag atttcaaggt
    42781 ttgaacggct agcttcaaag gaaataacgt ctgcatccat gttatcgata gctgggatga
    42841 tatctgtaaa ttctgagtaa cacatgtgag tgtggatttg tgtgtctggc gctactgttg
    42901 agtgtaccaa gcggaaggca ggaatagccc agtcaaggta gtcttcgtac cagtcgctac
    42961 ggcggagtgg caatttttca cgaagagcag cctcgtcgat ttggatgatt ttcacaccag
    43021 cagcttcaag gtcaagtact tcatccttga tagcaagggc gatttggaga gttgaatcct
    43081 tgatagagat gtcttcacgt gggaatgacc agttaaggat ggtaacaggt ccagtcaaca
    43141 tacctttaac aggtttgttt gtacgacttt gtgcatagct agaccattta acagtgatag
    43201 ggttaagacg agtgacatca ccccagatga ttggtggttt taccccacgc ataccgtatg
    43261 attgtaccca tccattttta gagaagaggt atcctgacaa gttttgaccg aagtactcaa
    43321 ccatgtcatt acgctcaaat tcaccgtgaa caaggacatc aaagtcaata tcttcttgcc
    43381 acttgatcca ttcgtcaatc gtttcagcaa ggaaagcgtc gtactctttt tgagacaatt
    43441 cacctttacg gtaagccaaa cgtttggcac gaacttcttt tgtttgaggg aatgaaccaa
    43501 tcgttgttgt tggaagagct ggaagtttga aagcttcttc ttggatagct tcacgttctg
    43561 caaaggctgg caaacgagtg tagtctgcgt ctgtcaagcc agcgatacgc gcacgaagtt
    43621 cagcattttc accaacacgc tcagtcgcaa agagttcttt gttagctgca agtgcttctt
    43681 ctccttgacc attgcggata gcatccaaat cacgaatctc atccaatttt tcaactgcaa
    43741 aggcaaagtg gttcaagatt gctggttcaa attcttcatt agctgttgta aatggcacat
    43801 gaagaagtga gcatgagctt gtcaagacaa tgttttcagc tgggatttgt tcaagaacag
    43861 ccaagctctt ttcgtagttg ttacgccaga tgtttttacc attgacaata cctgcgtaga
    43921 gagtcttgtc agctgggaag ccacctttaa ccaattcaag agttttctta ccttcaacga
    43981 agtcaagacc gatagcatct actggcaatt tcacaaggtc agcgtaaacg tcacgaacgt
    44041 caccgaagta agtttgaagc aatacttcaa gacctttttt gtcagccaaa agtttattgt
    44101 aaaggttcaa gaagagagct ttttcttcgg cagtcaaatc tttcacaaga gcagcttcgt
    44161 cgagttggat acgagatgca ccaagttcag ccaatttagc aaaaacttct tggtaagcag
    44221 ccactagact gtctacgaaa tcttctgctt tcacaccttc ttcaaagtct gacaattgaa
    44281 ggaaagtgaa tggacctaca aggacaggac gagtgttcaa tccaagttct tttgcttctt
    44341 ggaattcatc gaaaatcttg tgatctgcca attttacttg agtgtctttt tcaaatttag
    44401 gaacgatgta atggtagttg gtgttgaacc atttcttcat tggaagggcg cgaacgtccc
    44461 ctttttctcc ttggtaacca cgacccaaag cgaagtagcg ctcaaggtca gacaagtcca
    44521 agttttgaac tgaagcaggt accacgttga aaaggaaagc tgcatctagg aagttgtcat
    44581 agtgagaaaa gtcatttgat ggaatttcag tgatgccttt ttctttgaca atgttccagt
    44641 gtttagcacg caagtctttt gctgctgcta aaagttcttc ttctgagatt tcttttctaa
    44701 agtatttttc agttgtaaat tttaattcac ggaattcgcc caaacgaggg aaaccgatga
    44761 ttgtagttga catgatgtgt cctccaaaat ttgttgttga aactatctta acagaaaaga
    44821 aagcgtctgt ataattgtaa aaaattaggg tttgatatag tttgaaacta tatatctgtt
    44881 tcggacaaaa gaaaaagact tgaagcaaac gtctcaaatc ctttgtaatt cttactttac
    44941 agctatattc caattagaat actaaaacat gttattagta attcttataa gtgactatga
    45001 cctgttatta gaaaagacta taactgattc tagtcaactt tttccctgtt caagtgggac
    45061 gactgctagt gtctttccta aactggctag gacttttaag actgtatcca actgaggact
    45121 agtctttcct gtctccatcc tagctatgac aggctggctt attccactga cttcttccag
    45181 ctttttctga ctgattcctt gttcatacct agcctcaatc aactcgctca tgatagccac
    45241 tcgcatatca ctttcaagga tttcctcctt gctaaagagc tcagatggac atccttccaa
    45301 ttactcccaa tagcactatt cttcatcact taaccctctt ttttttacgt ctatgtattt
    45361 ttaaaaaaat gagcgaatta tgattcgata gattgaccag tgggtttaaa gttggtgcta
    45421 gcctatttct taagcgattt tccttttcta ggataaagca gatcctgctt gcttaacccc
    45481 aattttccac gatgaatcca atagtaaatg gttgaaattc ccacgttaac ccctttaacc
    45541 ataaccatca tttcaggcga aaatttttgg ttatgtatag tggagaatct tttcctttag
    45601 tttcttaaga ctgttgagcg tagtcggcag aataaacctc tttgaagcgc ccttttccaa
    45661 gacattgtcg gactgtccca cgcttgattt cagtgtggat agtttgagga acttttccaa
    45721 gcagagaggc aatttctcta tttgatttcc cttctttttt ccatctttcg attaagcgac
    45781 ggctatcgat tgtcaaatgt ttgccttttg tagtataatt gtcttgcatt tctgtgcctt
    45841 ttaatcattt caatcttaaa ttggactttt tttacttggg ttgtacttaa tctatgagga
    45901 agacaagaaa aagaatatca atcaagtaaa gtcacaaagt cacattagct ccgagcaacc
    45961 attgcaaatt gaggtactca cacaatgatt aaaacatttc tctctgccct ttcggtcatt
    46021 ctctttgtta tccctatcat aacttattct ttttttccat cttctaatct taatatttgg
    46081 ctatctacca gacctatctt ggcacagatt tatgccttcc ccttagctac tgcaactatg
    46141 gctgctattt taagtttcgt atttttttcc ctatcttttt acaagaaaaa taaacaaata
    46201 cggttttact ctggcatttt gctcttacta tcgctcatat tactattatt cggaacagat
    46261 aaaacccttt cttctgcatc aaataagact aaaaccttaa aattagtaac ttggaacgtc
    46321 gctaatcaaa tagaagcaca acatattgag cgaattttta gccattttga cgccgatatg
    46381 gctatattcc ctgaactagc taccaatatc agaggtgagc aagaaaacca gagaatcaaa
    46441 ctattgtttc atcaagttgg actttctatg gccaactatg atattttcac ttctccacct
    46501 accaatagtg gaatagctcc tgtgactgtg attgtcaaga aaagttatgg tttctataca
    46561 gaagctaaaa cttttcatac aacacggttc gggacaattg tattacattc gagaaaacaa
    46621 aatataccag atatcattgc cttgcatact gctcctcctc tgccaggttt aatggaaatc
    46681 tggaagcaag acttaaacat cattcataat caattggctt caaaatatcc aaaggctatt
    46741 attgcaggtg attttaatgc aactatgcgt catggagcac ttgcaaaaat aagctctcat
    46801 agggacgcat taaatgtact accacctttt gaaagaggaa cttggaatag ccaaagtcca
    46861 aaacttttta atgcaacaat agatcatatt ttattgccta aaaaccacta ctatgttaaa
    46921 gatttagaca ttgtaagttt tcaaaactct gatcatagat gtatttttac agaaatcaca
    46981 ttttaattat tttatactct tcgacaatct cttcaaacca cgtcagcctc gccttacagt
    47041 actcaagtac agcttacggc tagcttccta gtttgctttt tgattttcat tgagtattat
    47101 ataaaatcac ccctctagtg ttcataaact agagggggaa tttgtatcct actatcgttt
    47161 aacgcacttc tgcgttcact tttttttcaa gcgatgcttg gattttttcc atgtagcgtg
    47221 cgacttcttc gtccgttaag ctgtcttctg gattttggaa ggtcaagcta taagccattg
    47281 acttcatacc aagtcccaat ttctcacctg agaaaacgtc aaagagtttg atatctgtca
    47341 aacgtttcac gccggcagct tggatagcat ctataacttc ttggtgagtt actgctgcct
    47401 tgaggagaag ggaaacgtca cggctgactg ctgggaattt cgtgatttcc acaaatggag
    47461 cagcaggttg aagggcagct tcgatgactg aaaggttgag ctcagccaca tacgtttctg
    47521 gaatatcgta agccttagca gtgactggat gcacttggcc aagaaaacca agaacttggt
    47581 caccgagtga aatgactgct gtacgtcctg ggtgaaggct ggcaatctca gctgttgctg
    47641 tataggtcac ttctagtccc aagcgagtaa agagcgcttc taggattcct ttagcataga
    47701 agaaatcaac tggaactgct gctgtttgga aatctttttc agcaaccaag cctgtcaagg
    47761 caaaggcaaa actgttgatt tcatttggaa gttcttcttt tggattacct gtttgttcaa
    47821 agacttttcc aatctcgtaa agggccaagt ttttattctt acgagccacg ttgtaggcaa
    47881 cggtatcaag gatacctgaa atcatatttt gacggaggac tgaacgatcc acagtcattg
    47941 gccacatgag ttccgtaagg ttacttggtt gagccgtaaa ctcaactgct ttttcaggag
    48001 ttgttagagc ataggtgatg atttctgtca aacctgctcc ttcagcaatg gtacgaactt
    48061 gacggcggag tttttgtgtc acagtcaatt caccagctgt accatcgtct tttggaaggc
    48121 tggttggcaa gcggtcatat ccatagatac gagcgatttc ttcaaagaga tcagcttcga
    48181 ttgtgatatc ccaacgacga cgtggtacgc tgactgtaaa gctgtctgca tttccagaaa
    48241 gaccaaagcc aagacgacgg aagacgtctt cgacatcagc ataagacagc tcagttccga
    48301 ggacacggtt aacatcagca agagttgaag aaacttctac atctgaagta tcaagctcac
    48361 ccgctgaaac gataccctta cgcaccgtcg cacctgcaag ttccgcaatc aggctagctg
    48421 ccgcatcaag ggcttcatta actgttgcca cattaattcc tttttcaaag cgagaagatg
    48481 actcagaacg aaggttcagg cgaccacttg tcttacggat agatttgcca ttgaaaacag
    48541 cagcttcaag gacaacatga ctagattttt cagagatttc tgttgcttga ccacccatga
    48601 cacctgcaag ggctactggc ttgtctgcaa cagtgatgac taggtcattc acgtccaagt
    48661 cacgttcttc accgtccaag gtcaccaatt tttcaccagc acgcgcttca cgcacacgga
    48721 tgtcagtccc ttcaaatgtg tccaagtcaa aagcatgcat aggttgacca aagtagagca
    48781 ggatgtagtt tgtcacgtct acaacgttat tgatgggacg gatgccttcg ttcatgagaa
    48841 ggttttgcaa ccattgtgga cttggtgcga tagtcacatt gtccaagata cgagctgcat
    48901 agtaaggcgc cttgtctgtc tcaatgccca cagaaagggc atctgtcgca gcttcatttg
    48961 tttctgtcaa agtaaattct ttaaagttga ctgccttgtc atatatggct gccacttcgt
    49021 gagccactcc acgcatagaa agggcatctg cacggtttgg tgtgatagaa aattcgatga
    49081 tttcatcatc caagtctaga tatgaaaaga cttcctcacc tggaacggca ttttctggca
    49141 aaatttgaat accatctgcg aatttcttag gtacaactga gtcagaaata cccaattcac
    49201 caagtgaaca gatcattcca agtgactcta agccacggat ttttcctttt ttgattttgt
    49261 aattgtcagc gatacgagct cccggaagag ccaccataac cttgatgcct gcacgcacat
    49321 ttggggcacc acaaacgatc tgacgctctt cttcttcgcc aacgttaacc tgacaaacat
    49381 gaaggtgagt ttctggcaca tcttcgcagg acaagatctc accgacgaca atttttgaaa
    49441 gaccggcagc tggtgattcg acaccttcga cctcgatccc tgtggttgac attttttcag
    49501 ccaactcctg tgatggcaca tcaatgccca ccaattcttt taaccattta taagatacaa
    49561 gcataattta gttctccaga atgaccattg ccacactggt tcttttcctt tcctatcatt
    49621 tcaatagaag aattctcttc ttaccttaat ttctttctca gtaaccaatc cgtatctact
    49681 ttttgaccaa ccataaaatg atgttggcta aatttttcaa aaccatatcg gttataaaac
    49741 gcttgagctt ttgtattatg ctcccaaaca cctagccaag cccaagaaaa actatttttt
    49801 gtagcaagtt caagtgcgaa ttcaaacagt tgcttaccta gtccaaatcc ttggaatttt
    49861 tgtagcacat agaggcgttg aatttcaaaa gcgtcctcta attctctctc agtttgagca
    49921 cttccccagt tgactttgag aaaaccagct atctcctcct catgcataat gaaataggtt
    49981 tcagagtcag gatttcccaa ctcagttgac aaagttttca gactataagc ctcttcaaag
    50041 tattcctgta actgctcttc cgtattatca tacgcaaagg tttcacgaaa ggcttgtttg
    50101 gcaattttag ccaacacctc aacatctgcc atttctactt ttctaatcat tatttaaact
    50161 gttctgagaa gcggacatct ccttggtaga atccacggat atcgttgatt ccataacgga
    50221 gcatagctac acgctcttgt ccaagaccaa aggcaaagcc agagtataca gtcgcatcga
    50281 taccactcat ttcaaggaca cgtgggtgaa ccataccggc ccccataatt tcgatccaac
    50341 ctgttttctt acatacgtta cagccttctc caccacattt gaagcaagaa acatccacct
    50401 caacagatgg ctctgtgaat ggaaagtaag atggacgcaa acgaatttga cgctcttcac
    50461 caaacatttt ttggacaatc aactgaagcg ttccttgaag atcagccata gagatatttt
    50521 tcccaactac caagccttcg atttggtgga attggtgact gtgggtcgca tcgtccgtat
    50581 cgcgacggaa gacacgccct ggcgagatca tcttcaaagg acctttagaa aaatcatggg
    50641 catccatagc acgcgcctga actggagacg tgtgggtacg gagcaagatt tcttcagtga
    50701 tatagaaagt atcctgcata tcacgagctg ggtggtcttt tggaaggttc atacgttcaa
    50761 agttatagta gtcttgctcc acttcaaaac catccacgac ttgataaccc ataccgatga
    50821 agatatcttc gatttcttca ctggtttgtg tcaaaacgtg atggtgacca gtcgcaactg
    50881 gacgacctgg aagcgtcaca tcgatactct cgctagccag ttgagccgcg actttctttt
    50941 cttccaagag cttagctgtt tcttcaaaag cagcagtcaa gacatcacga gcttcattga
    51001 cgtgtttccc gatgattgga cgcatctcag cagaaacatc tttcatccct ttgaggattt
    51061 cagtgagcga acccttttta ccaaggacag agacacgcaa atcttgcatc tctttttcat
    51121 ttccagcagt aatctgcttc aagctagcca gcgtttcttc gcgaagcgct tttaattgtt
    51181 cttcaatagt tgacatattt cctccatcag tctctcgtag ataaaaagaa aaccacatgc
    51241 caaaaactcc actcggagcg ttgacacgcg gtaccatccg ttttcatctg acaagtcaga
    51301 ccttcatttc taaatccatg cgcaagtgaa ttcacccagc tttcatatag agagcttgca
    51361 gtcacggctc tcctccctga tatacttccc ttgggctact agtctttcag attcctattc
    51421 aattactact tagtttatca gatttttacc attcttgcaa gacctatctt acttctgctt
    51481 gttagcttat tcttatctaa ctttatagcg gattgaaata agatgaaaac aaatcgattg
    51541 ggaaagtaaa attaatttct ataaatgttt tagcaattgt ttcgtactat tttagattca
    51601 gtctactata tataacccat ctatcctaag ttaactattt ataatcggct ctctgtaaca
    51661 aaattaaatt aattaatccc cctataaaat aaagaggttt agaatttgat gtcttccaaa
    51721 cctctttatt tcatatttaa tgagatgttg ccttaaccgt gataatatct aatcatcaat
    51781 aaacaaacta tttgaataag gattctccat ttgattcaat cactccttta taccaagtaa
    51841 aggacatttt cttatatcga ttgaatgtgc catttccatc atcatttcga tcaacataaa
    51901 tgagaccgta ccttttagaa agttgtgcag tggacataga aacgcagtca atacatcccc
    51961 aagatgtata gcccataatt tcaacaccat cctgtagagc ttcagcaact tgcaataaat
    52021 gttctttcat atactgaatt ctataatcat cttggacggt taagttatta agttcatctt
    52081 ttattagttg atctttagca cctaatccat tttctactat aaataatggg atttgataac
    52141 ggtcataata tctatttaaa attatacgta gtccaattgg atcaatttgc catccccact
    52201 ctgaagactc taaataagga tttactaaac caccaataat attcccttct cctgaattat
    52261 actgtgttgg aagagcagat tgagtcacac tcatgtaata gctaaaggat aaaaaatcta
    52321 cggtataatt ttttaataac tctgcatctt cagctgcaaa ctctatgtta atgtcatgtt
    52381 ccttaaaata tctttttgca taattcggat aataacctct aacatgcaca tctgaaaata
    52441 gataatttag attctcatac tcatgagtcg cccatacatc ttttggattt ggagtcattg
    52501 gataagctgg catagctaat accatacacc ccaccttaaa ctctgaatta atctcacgag
    52561 caatttttgt aaccaaactt gaggcgacta attcatgatg tatagcttga tataattctt
    52621 gtttcgaaag attctcctta ggtatatcta ttcctccact agtaaatggt aattccaaaa
    52681 cagagtttac ttcgttaaat gtaagccaat atttaacttt atctttatac ctttctaaaa
    52741 ctgttcgagc aaatttttca taaaaatgaa tcattctcct atcaacccat ccatgatatt
    52801 ttcttgctaa atataatgga gtctcatagt gtgaaagagt tacaagtggc tctatcccgt
    52861 gagcatgtag ttcatcaaac aattcatcat aatatttcaa accagcttcg ttaggttctt
    52921 cttcatctcc ttttggaaaa attctactcc atgcaataga agtacgaaaa acattaaagc
    52981 ccatttcaga aaacaaggat atatcttcct tatatttatg ataaaaatca atacctatca
    53041 attttaagtt atcttctgta ggattttctg ttgcttctcc taatccacct ttgggtaaca
    53101 catcctgaac tgataagccc ttaccatctt cattatatgc tccctctact tgattagctg
    53161 caacagctcc accccaaaga aaatcatctg gaaaaatggt cataactttc ctccattata
    53221 atattaccag taattcctta gaatgctcga ttgtctgatt attaggtaat actaatacat
    53281 ctagaaaatc attggtattc gttacaatta ctggtgtaac tgtttcgtag cctttagtct
    53341 tgattaaatt caagtccatt tcaaaaatca actgattttt gaaaactctg tctccttctt
    53401 ctacatgact aataaaacct tgacctttta gctcaacagt atctaatcca atatgaatta
    53461 gtaactcaac accctcatca ctcttcaatc caattgcgtg cttagtcgga aaaatatttg
    53521 taattttccc atcaaatggt gcataaacct taccttcact tgggataatc gctactccgt
    53581 ctccaattag tttatctgaa aatgttttat cctggacatc gcttaacgga atgatttctc
    53641 ctgatatagg agaaaatatc atttttttat ttgaaactcc agctttaact tctaaattac
    53701 tagaactctc ttcttcatcg attccaaata tataagctaa tacaaaggta ataacaaccg
    53761 aaatgaccgc cacaattaaa gcatttacaa tatttgatgg tacatcagaa taaataaatt
    53821 gaggcaacgc tatcaaagat gggacagcaa atagatacgc tttaacacta gtaagacctg
    53881 caaataatcc cgctaatcca ccaccaatca tagctgcata aagcggtttt ttatatttta
    53941 aagtcacacc atataatgca ggttcggtaa ttcctgcaag taaggctgag aaacctgctg
    54001 caaaagcaat ttgttttgta ttattatttt tactctttaa tgcaacagcc atcgaagcag
    54061 ccccttgagc taagtttgac cctaacattg ctggaagaat taatacgtct ggagtagcaa
    54121 tagatgccgc caaaaaaata ggtgcaaaag cccaatgcat tccagtcata acaataaatg
    54181 gcataatagc accaagaata gctaatgtaa gccatccagc tacaccatac atttgcccaa
    54241 ctagatttga taatccttca ccaacaatta ctccaatagg tccgactaca actaaggcaa
    54301 tacagcttga tactaataat actagcgtag gttgcaaaaa actcttagta acagctggtg
    54361 ttaatttagc aatcattttt tcaatatatt tcatcaacca aaccataata agaattggaa
    54421 cgactgacga accataacta gctggtgtca caggtacacc aaataaacta agaggattcc
    54481 ctgattgcac catttgaaca aaatttggat ggagaagtac acctgctaca gacatagcta
    54541 atgtagatgt tacttttaat ttttgtgatg cagaataagc taataacagc ggtaagaaat
    54601 aatatggcgc atccccaaaa aatgtcaaaa aagcaatagt ctgagaatct gattgcaata
    54661 taccaagcat tggtaaaata attaccaaga ctttcagcat acctccccct aacattgctg
    54721 gaatgattgg agtcatggaa ccagcgatat actcaatgat tctttctaaa atattccctt
    54781 tgtgcccttg aacaactgaa tcggattcaa aattgccaag tttaacgaat tctttataat
    54841 aattagctac atcattacca agtataattt gatattgtcc attctttttc ataataccta
    54901 ttacacctgg tatcttcttc atatcatcat cattgactaa attttcatct tttaattcta
    54961 atcttaaacg tgttacacaa tgggtaactc tattgacatt tttttcacct ccaattacat
    55021 cgaggatttt ttgtacctta tctttataac tcatggtatt ctcctattct attaatctaa
    55081 attttttgtt aagcgacgaa tatgagccat caaataaact aattcactag aagtcagcaa
    55141 ataattgtac tcagtttgta taaacattgc cacctgttca ccacattcat attctctagg
    55201 atatttattt ttcattaatg ctaacaagtc ttcatcatca tcgtcacaat aagttgtatt
    55261 ttcaaccaag cgatgggcaa ataattttat atgagttatg aatctataat aatcaataga
    55321 atcttggtta aactcagtac aatagaaatc ttgaatgatt ttctcaattc ccataattat
    55381 ttcagtgatt ttatacgact cttgaaaatt attttctaaa ttagcattaa caaaatgtag
    55441 cgctatgaat gcagcttcgt caattggaag ttcaatacct aactcttttt ttattatttg
    55501 taaagccctt ttcccaagt
//
LOCUS       DAVMJI010000012        50067 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.012, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000012 DAVMJI010000000
VERSION     DAVMJI010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50067
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.012"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            582..788
                     /locus_tag="VYR58_000846"
     CDS             582..788
                     /locus_tag="VYR58_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622038.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
     gene            785..979
                     /locus_tag="VYR58_000847"
     CDS             785..979
                     /locus_tag="VYR58_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622039.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFICGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            966..1850
                     /locus_tag="VYR58_000848"
     CDS             966..1850
                     /locus_tag="VYR58_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622040.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENIIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            1852..2589
                     /locus_tag="VYR58_000849"
     CDS             1852..2589
                     /locus_tag="VYR58_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622041.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKINNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLGNWIGAALLLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            2589..3686
                     /locus_tag="VYR58_000850"
     CDS             2589..3686
                     /locus_tag="VYR58_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV3622042.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILTVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            3688..4287
                     /locus_tag="VYR58_000851"
     CDS             3688..4287
                     /locus_tag="VYR58_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3622043.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEMVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            4712..5722
                     /gene="ccpA"
                     /locus_tag="VYR58_000852"
     CDS             4712..5722
                     /gene="ccpA"
                     /locus_tag="VYR58_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV3622044.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(5928..6890)
                     /locus_tag="VYR58_000853"
     CDS             complement(5928..6890)
                     /locus_tag="VYR58_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV3622045.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            6956..8344
                     /locus_tag="VYR58_000854"
     CDS             6956..8344
                     /locus_tag="VYR58_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV3622046.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            complement(8379..8831)
                     /locus_tag="VYR58_000855"
     CDS             complement(8379..8831)
                     /locus_tag="VYR58_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV3622047.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            8994..9287
                     /locus_tag="VYR58_000856"
     CDS             8994..9287
                     /locus_tag="VYR58_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622048.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVVKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            9443..10657
                     /locus_tag="VYR58_000857"
     CDS             9443..10657
                     /locus_tag="VYR58_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV3622049.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            10802..10936
                     /gene="rpmH"
                     /locus_tag="VYR58_000858"
     CDS             10802..10936
                     /gene="rpmH"
                     /locus_tag="VYR58_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV3622050.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            11199..11864
                     /locus_tag="VYR58_000859"
     CDS             11199..11864
                     /locus_tag="VYR58_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV3622051.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKLETTPGGDKGGNTGSSD
                     ANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKNKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRLVAPNAA
                     PKTTSAPQATAGTMQNVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTR
                     RRK"
     gene            12169..12942
                     /locus_tag="VYR58_000860"
     CDS             12169..12942
                     /locus_tag="VYR58_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV3622052.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMIISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            12942..13502
                     /gene="rnmV"
                     /locus_tag="VYR58_000861"
     CDS             12942..13502
                     /gene="rnmV"
                     /locus_tag="VYR58_000861"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV3622053.1"
                     /translation="MKEKISQVIVVEGRYDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            13574..14473
                     /locus_tag="VYR58_000862"
     CDS             13574..14473
                     /locus_tag="VYR58_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3622054.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            14793..15089
                     /locus_tag="VYR58_000863"
     CDS             14793..15089
                     /locus_tag="VYR58_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV3622055.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            15166..17196
                     /locus_tag="VYR58_000864"
     CDS             15166..17196
                     /locus_tag="VYR58_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV3622056.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQGLFTDYL
                     QNFSSESVEVTSQKYYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDCLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            17198..17839
                     /locus_tag="VYR58_000865"
     CDS             17198..17839
                     /locus_tag="VYR58_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622057.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            17832..18125
                     /locus_tag="VYR58_000866"
     CDS             17832..18125
                     /locus_tag="VYR58_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622058.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            18376..19248
                     /gene="rsmA"
                     /locus_tag="VYR58_000867"
     CDS             18376..19248
                     /gene="rsmA"
                     /locus_tag="VYR58_000867"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV3622059.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLMPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            19250..20128
                     /gene="rsgA"
                     /locus_tag="VYR58_000868"
     CDS             19250..20128
                     /gene="rsgA"
                     /locus_tag="VYR58_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV3622060.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            20139..20795
                     /locus_tag="VYR58_000869"
     CDS             20139..20795
                     /locus_tag="VYR58_000869"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV3622061.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            20758..21420
                     /locus_tag="VYR58_000870"
     CDS             20758..21420
                     /locus_tag="VYR58_000870"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV3622062.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            21422..22678
                     /locus_tag="VYR58_000871"
     CDS             21422..22678
                     /locus_tag="VYR58_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV3622063.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLYFQENEEEYED"
     gene            22668..23609
                     /locus_tag="VYR58_000872"
     CDS             22668..23609
                     /locus_tag="VYR58_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV3622064.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            23876..24703
                     /gene="purR"
                     /locus_tag="VYR58_000873"
     CDS             23876..24703
                     /gene="purR"
                     /locus_tag="VYR58_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV3622065.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            24770..26020
                     /locus_tag="VYR58_000874"
     CDS             24770..26020
                     /locus_tag="VYR58_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV3622066.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            26146..26940
                     /gene="pflA"
                     /locus_tag="VYR58_000875"
     CDS             26146..26940
                     /gene="pflA"
                     /locus_tag="VYR58_000875"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV3622067.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(27015..27941)
                     /gene="yidC"
                     /locus_tag="VYR58_000876"
     CDS             complement(27015..27941)
                     /gene="yidC"
                     /locus_tag="VYR58_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV3622068.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(28019..28297)
                     /locus_tag="VYR58_000877"
     CDS             complement(28019..28297)
                     /locus_tag="VYR58_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV3622069.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            28331..29071
                     /locus_tag="VYR58_000878"
     CDS             28331..29071
                     /locus_tag="VYR58_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV3622070.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            29127..29810
                     /locus_tag="VYR58_000879"
     CDS             29127..29810
                     /locus_tag="VYR58_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV3622071.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            29922..30914
                     /locus_tag="VYR58_000880"
     CDS             29922..30914
                     /locus_tag="VYR58_000880"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV3622072.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            30979..31518
                     /gene="rsmD"
                     /locus_tag="VYR58_000881"
     CDS             30979..31518
                     /gene="rsmD"
                     /locus_tag="VYR58_000881"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV3622073.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            31508..31996
                     /gene="coaD"
                     /locus_tag="VYR58_000882"
     CDS             31508..31996
                     /gene="coaD"
                     /locus_tag="VYR58_000882"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV3622074.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            31980..33017
                     /locus_tag="VYR58_000883"
     CDS             31980..33017
                     /locus_tag="VYR58_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV3622075.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            33075..33305
                     /locus_tag="VYR58_000884"
     CDS             33075..33305
                     /locus_tag="VYR58_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV3622076.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            33329..34612
                     /gene="murA"
                     /locus_tag="VYR58_000885"
     CDS             33329..34612
                     /gene="murA"
                     /locus_tag="VYR58_000885"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV3622077.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            34605..34793
                     /locus_tag="VYR58_000886"
     CDS             34605..34793
                     /locus_tag="VYR58_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV3622078.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            34832..35656
                     /gene="endA"
                     /locus_tag="VYR58_000887"
     CDS             34832..35656
                     /gene="endA"
                     /locus_tag="VYR58_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV3622079.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            35947..37278
                     /locus_tag="VYR58_000888"
     CDS             35947..37278
                     /locus_tag="VYR58_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV3622080.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELISQNKQFILTNDKVKNGRVTKVKIQITEVEIEEETE"
     gene            complement(37476..37546)
                     /locus_tag="VYR58_000889"
     tRNA            complement(37476..37546)
                     /locus_tag="VYR58_000889"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(37512..37514),aa:Cys,seq:gca)
     gene            37962..41573
                     /gene="rpoB"
                     /locus_tag="VYR58_000890"
     CDS             37962..41573
                     /gene="rpoB"
                     /locus_tag="VYR58_000890"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV3622081.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            41606..45283
                     /gene="rpoC"
                     /locus_tag="VYR58_000891"
     CDS             41606..45283
                     /gene="rpoC"
                     /locus_tag="VYR58_000891"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV3622082.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     TEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            45394..45807
                     /gene="ndk"
                     /locus_tag="VYR58_000892"
     CDS             45394..45807
                     /gene="ndk"
                     /locus_tag="VYR58_000892"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV3622083.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(46736..47368)
                     /locus_tag="VYR58_000893"
     CDS             complement(46736..47368)
                     /locus_tag="VYR58_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622084.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(47370..49385)
                     /locus_tag="VYR58_000894"
     CDS             complement(47370..49385)
                     /locus_tag="VYR58_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV3622085.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            complement(49835..50005)
                     /locus_tag="VYR58_000895"
     CDS             complement(49835..50005)
                     /locus_tag="VYR58_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622086.1"
                     /translation="MKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
BASE COUNT        14693 a         9506 c        11378 g        14490 t
ORIGIN      
        1 acagagatat gtgagtgtgt atttttaaaa ctagatatta tatacattaa gagggaatca
       61 gtttggttct ctcttttttg attttcagta attcattttg gcagcgtata ctttttgtct
      121 ccagtctttt caataaatac cgtagtttag gtatacacat tgaaatttaa cagattttat
      181 aactcttata aatttttaag aaagcaatag aagggttttg ttcaacgtat aatatagaga
      241 attgaaataa gatatgaaca gctctatcag gaaagttaaa ttaatttata gaaatatttt
      301 agtatttaag gcctactgtt atagattcaa tacactatat atgtgtttgt ctgataaaaa
      361 tttctactct ttttgatttt aaataagtat tagtttacat tatggtgtga attgggtttg
      421 atatctcttt tgaggaagtt gccttagatt tttctgattg tgttttattg tatagtgtat
      481 cttgcttgtt ttgaacagaa tttttatgac atttgtcata ttttctagtg acagaagctt
      541 ctgcctcctc tgattttaaa agactataat tgtagtatga aatgggggaa gaagagatga
      601 gaaataaaat gattattgca atgagtttag tagtagcagg agttatgacc tatctcatgt
      661 tttcgggatt ggatgaggat ttctaccatt ttccttggaa ggtctttgct ggctttggaa
      721 tcatgtcttg gcttgttaga gaaggtttga aattagtcag agatgtgaaa aaggagtttg
      781 aggaatgaag agagggatca tctatttctt tatcggcctg tcactcttgg tatggttagt
      841 ggaaatgttt actgattggt ttgatcaagc cttgcttcgc caattcattt gtggtgcttt
      901 ggggtttgga tttatgattt tcgtcgtttt ccctatggga atggagtggt tgaaaggaga
      961 gtctcatgac tgtggttaaa gttgaaaaat tgagtaagaa aataaaagac aaggaaattt
     1021 tgcggaacat ctcctttgaa atcaacgatg gtgaatgtgt tgccttaatt ggtccaaatg
     1081 gtgccggaaa gacaacactc ttagattgtt tgcttggaga taaactggtc acaagcggtc
     1141 aagtatctat tcaaggttta ccagtgacga gttctaagtt agactatact agggcttacc
     1201 tccctcaaga aaatataatc gttcagaaat taaaagttaa agagttgatt gctttctttc
     1261 aacgtatcta tccaaatcct ttgagcaatc aggaaattga tcaactattg cagtttgtca
     1321 agcaacaaaa agaacagttg gcagaaaaat tatcaggcgg tcaaaagcgt ctcttttctt
     1381 tcatcttgac cttaattggg cgaccaaaga ttgttttttt agatgagcct actgcgtcca
     1441 tggatacctc aactcgtcaa cgtttttggg aaattgtcca ggagttaaaa gcgcaaggag
     1501 tcaccattct ctattcgtcc cattatattg aggaagtgga acacactgca gaccgcattt
     1561 tgctcttaaa taagggagag ttgattcgag atacgacgcc tctagctatg cgtagcgagg
     1621 aaatagaaaa gcactttatc cttcctatag cttacaagga agtcgtagag cagtcaaatt
     1681 tggttgaaaa ctggacccta aagcaagatt ctttacaagt agtcactcga gaagcagatg
     1741 ctttctggga actattagcc caagcaggat gtaggatgca agaaatcgaa gttaataatc
     1801 gtagtttgtt gaatacaatc tttgaagaga cgcagaaggg agataactaa gatgaaacga
     1861 tggatagcac ttagtaagat agaattttta ttgaccaaac gacaattaat ctattatcta
     1921 ttgtcggtag ggatgccgac ggctttctat ttattttttt ctggtatcta tcaggacaca
     1981 ccaggtgaac tcgcgaattt tatgcgtgat tatcttatct ccatgactgc attttccatg
     2041 atgtcaacag ctatcttctc attcccagtt gttttacata ccgacaagat caacaactgg
     2101 cagaaaacat tgcgtcatag ccctgtaaat atggtagaat attatctatc aaagataaca
     2161 agtatgctgg ttgattattt ggtttcaatc ttggtggttt tctcagttgg gcattttgta
     2221 agaggtgtgg acatgtctct tggaaattgg attggggctg cacttttgct gatagtagga
     2281 agtattgcct tcgtagcgct tggtttgacc ttgactctct taccaactag tcagttgatg
     2341 tctgtcgtgg gcaatcttct ttatctaggg ttggctgttt taggtggact ctggatgcct
     2401 atctctttat ttccagactg gatgcaagta gtaggtaagt gtctcccgac ctatcagttg
     2461 atggagttgc tcaagacctt cttaaatgag ggtggcatca atctatcagc cacagtttat
     2521 ttacttgttt tttcagtagt tttgtttggt ttgaccattt accttcaagg tcataaggag
     2581 aatgcttaat gcttgaaaga ctgaaaagca tacattatat gttttggatc agtttaattt
     2641 ttatggtttt ccccatccta actgtagtga ctgggtggct ttctgcctgg catttattga
     2701 ttgatattct atttgtagtg gcgtatttgg gtgttttaac aactaagagc cagcgtctat
     2761 cttggctata ttggggcatc ctgctgactt atgtagttgg gaatactgcc tttgtggctg
     2821 ttaattatat ctggtttttc tttttcctat ccaatctctt aagctatcat ttcagcgtag
     2881 gtggtttaaa gtctttacat gtctggactt ttcttcttgc tcaagtcctt gttgtgggtc
     2941 aactgttgat ttttcagaga atcgaagttg agtttctatt ctatctactt gtaattcttg
     3001 cttttgtcga tttaatgact tttggcttgg ttcggattcg aattgtggag gatttgaaag
     3061 aagcacaggc taagcaaaat gcccagataa atctattgct tgctgaaaat gaacgcaatc
     3121 gtatcggtca agatttgcat gatagtctgg ggcatacctt tgctatgctt agtgttaaaa
     3181 ctgatctagc cttgcagtta tttcagatgg aggcttatcc acaggtggaa aaggaattaa
     3241 aagaaattca ccagatcagc aaggattcca tgaatgaagt tcgaactatc gtggaaaatc
     3301 ttaagtctag aactttgaca tccgaactag agactgtgaa aaagatgtta gaaattgctg
     3361 gaattgaggt ggaaacggat aaccaactag atactgctag ccttactcaa gaattggagt
     3421 caatggcttc tatgattttg cttgagttgg tgaccaatat catcaaacat gccaaagcgt
     3481 ctaaagctta cttaaaatta gaacggacag agaaggaact cattttaaca gtaagtgatg
     3541 atggctgcgg ctttgctttt ctaaaaggag atgagctcca tacagtccga gatcgtgttt
     3601 ttccattttc aggagaagta agtgtaatca gtcagaaaca tccaacggaa gtgcaagttc
     3661 gactacctta taaggagaga aactaagatg aaagtattag tcgcagaaga tcaaagtatg
     3721 ttgcgagatg ccatgtgtca attgctcacg cttcaaccag atgtggagtc tgtccttcaa
     3781 gccaagaatg ggcaagaagc aatccaacta ttagaaaagg agtctgtaga tatcgccatc
     3841 cttgacgtag aaatgcctgt taagacaggt cttgaagtct tggagtggat acgatcagaa
     3901 aagcttgaaa caaaggtggt tgtggtgacg accttcaagc gtgctgggta ttttgaacgt
     3961 gcggtcaagg ctggagtgga tgcttatgta ttaaaggaac gaagcattgc agacctcatg
     4021 caaaccttgc acaccgtcct cgaaggacgc aaggagtatt cgcctgaatt gatggaaatg
     4081 gtgatgaccc gtcccaatcc gttgacagaa caagagattg ctgtcttaaa gggaatcgcc
     4141 cggggcttat ccaaccaaga aatcgcagat cagctttacc tctcaaacgg aactattcga
     4201 aactatgtca ccaatattct ttcaaaactg gatgctggta atcgaacaga ggcagctaat
     4261 atcgcaaaag aatctggttg gttatgatga tataatattt tcatgaagac tatgtgctaa
     4321 aattgacggt agtgaatgga acaataccta tagtagattg aaactagaat agtacacctc
     4381 tacttctaaa acattgttag aaatcgattt gactgtcctg atcgatttat cctgttctta
     4441 tttcatttta ctataacttt aggagggctt agtttcctcc tttttgttta gtctaaggtg
     4501 gtagcaagga gctaaaccta ggttttctat gaaatttttt caatcaatct tcaaaaaaca
     4561 cttgaaagtg tttacaatta gtgatagaat ggaataagta gaaatatgaa aacgaaattt
     4621 tcacatcttc acttttgtaa gtagatatag agcttcaatc agtacctcta cttgtaaaag
     4681 aatgtgtgag atagaaagga caggaaaagg aatgaatgca gatgatacag taaccattta
     4741 tgatgtcgct cgtgaagcag gtgtttccat ggcgacggtc agccgtgtgg tcaatggcaa
     4801 taaaaatgta aaagagaata cccgtaaaaa agtgctagag gtaattgatc gtttggatta
     4861 tcgtccaaat gcagttgcgc gtggtcttgc aagtaaaaag acaaccactg tcggtgtcgt
     4921 gattccaaat attaccaatg gttatttttc gagtttggct aaggggattg atgatattgc
     4981 agaaatgtac aagtacaata ttgtcctagc taatagcgat gaagataacg agaaagaagt
     5041 ttctgttgtc aataccctct tttcaaagca ggtagatggc attatctata tggggtatca
     5101 cttgacagat aaaattcgct cagaattttc gcgttcacgt actccgattg ttctcgcagg
     5161 aactgtcgat gttgagcacc agttgccaag tgtcaatatt gactataagc aagcaacaat
     5221 tgatgcagtg agttaccttg ctaaagaaaa tgagcgtatt gctttcgtta gcggtccgct
     5281 agtggatgac atcaatggta aggttcgttt agttggctac aaggaaacct tgaaaaaagc
     5341 aggaatcact tatagtgagg gtttggtatt tgaatctaaa tatagctatg atgatggtta
     5401 cgccttagca gagcgtttga tttcatcaaa tgcaactgca gcagttgtga caggtgatga
     5461 gttggcagca ggagtcttga acggtttggc tgataagggt gtttctgtgc cagaagattt
     5521 tgaaattatt actagtgatg attcacaaat ctcacgcttt acccgtccaa acttgacaac
     5581 gattgcccaa cctctttatg accttggtgc cattagtatg cgtatgttga ccaagattat
     5641 gcataaggaa gagttggaag aacgtgaagt tctcttacct catggtttga cagaacgtag
     5701 ctcaacacga aaacgtaaat agaaaaaatc agggaatcga gaagatttcc tgattttgtg
     5761 ctcttaaaca agagatgttg acttaatgaa taccatagag cggactaggc ggctggttaa
     5821 aggctgcgca acacactgtt ttgaggttgt ggatgaaact gacgaagtca gtaaccatac
     5881 atacggtaag gcgacgtgac gtggtttgca gagattttcg aagagtatta gccttccata
     5941 tagtctttca aagcctgtcc tgttagtccg gcattgaggg cgatgaggag tttcaagcga
     6001 gctttttggg cattgagttc tttaacaaag aaaacgcctg ctttttgcaa ctgtacgccc
     6061 ccaccctggt aggcataaac aggctcggca ataccgttaa agcatcgtga taccagagcg
     6121 actgggattc ctttttgcag aaggctttct aatttttgag ccgtttcttt gggaatatta
     6181 ccagctccga aggcttggat aatcaaaccg tccaagtgtt ctaaatccag catatcaatc
     6241 agctcatctg tcataccagc ataagccgag atgataggga ctaaaccttg tatgtgatca
     6301 aggtcaaagc gaacacgagg ttcagctgtt ttgaagtaga ggatttcctg tttcatgatg
     6361 agaccgaggg ggccatgtgt tggagtctgg aaggtgctga cattagtcgt atgtgttttg
     6421 gtgacatact tggcagcgtg gatttcatcg ttcataacga ccaaaactcc tttgtcagca
     6481 gccctgtcat cgctggccac tcgtaaagca cttaggtaat tataaacacc atcactaccg
     6541 agctcattgg agctacgcat ggctcctgtt agaacgatag gcatatgggg aacttccatg
     6601 gtatcaagga aataggctgt ttcctctaaa gtatcggttc cgtgtgtgat caccactcca
     6661 tcgtagttat ctgcttcctc tttaattttc tggtagagga ccagcatatg tttgggtttg
     6721 atatggggac ttggaaggtt aaaaaagtcc aaggcgtgga cttggattcc ttcaagtggg
     6781 ttggacacat ggttcatggg attatctgaa ctcgtcacaa cagcgccaga agcatcggcc
     6841 tgcatggaaa tagttccacc cgtatgtaaa acaaggattt tcttaggcat gatttactca
     6901 ctctttctga aatgtggtat aatcattgta tcacaaaagg ggagattggg ataggatgga
     6961 agtcaaagct gttttttttg atatcgatgg aaccttggtc aacaatcgca agagtgtttt
     7021 gaaatccact aaggatgcga ttaagattgt caaagaacaa ggggtactag ttggcgtagc
     7081 gacagggcga ggaccttttt ttgttaagga attgatggac gatttggatc tggattttgc
     7141 ggtaacctat aatggccagt atatctttag taaagacaga gtcttgttca cgagccctat
     7201 ttccaagtta catttgcgcc atctaattag ctatgctaaa aaagagggca cggagattgc
     7261 tctagggacc aaggatgcca tgttgggttc taaaatcatg tcctttggtc tgggttcttt
     7321 ttcccaacga attagtcgct tcgttccctc tgttttaact cggacggtga gtcagtcttt
     7381 taatcgcatg gtcagcaagg ttgttcccca aaaggaagag gacctgcttc acctgatgaa
     7441 tcagcctatc taccaagttt tgatgctgat gacaccagaa gaatctgaga aggcggcagc
     7501 tgattttgaa gacttgaaat tgacacgtag caatcctttt gcatcggatg tcatcaatca
     7561 gggaaattct aaattagaag gcattcgccg agttgggaaa gaatatggct ttgacctcaa
     7621 ccaagtcatg gcttttggtg actcagataa tgaccttgaa atgctggctg gcgtcggtat
     7681 gtcggtcgct atgggaaatg gtagtagcag tgtcaaggaa gctgccaagc acattaccac
     7741 tagcaatcaa caagatggga tccacaaggc cttggaacat tttggtgttt tgtcttcaga
     7801 aaaagttttt gtcagccgtg actatcattt caataaggtc aagaccttcc accacatgat
     7861 ggatgaacga acccaagaag aacctcgagc ttgggattta gagggtgcaa cccatagggc
     7921 tggttttaaa atagaagaat tggtggagtt tgttcgatca gccagtcctt ctgaagaaga
     7981 ttttggtcaa gctgtatcgc aacttcatca ggcccttgat aaggcagcag gtaaagtagc
     8041 caagaagaca cctgctcagc aagatttgat agggcaagtg gatgccttga ttgacacgct
     8101 ttacttcacc tacggcagtt ttgtcttgat gggggtggac ccagaacgta tttttgatat
     8161 tgtccatcag gccaatatgg ggaaaatttt tccagatggc aaggctcatt ttgatccagt
     8221 gacccataaa atcttaaaac cagataattg ggaagaaaaa tatgctccag aacctgctat
     8281 taaaaaggaa ctgcagcgcc agctcaaggc ttacgaacgc cataaagaga gaaataaatc
     8341 gtaaacaaaa aggagctagg ggctcctttt ctttgtgatt ataaggtttt ttcttgttct
     8401 ctcacaacca gcaaatcgac cttagcatgg cggagtatgt attcagatga agagccgact
     8461 aagaggcgtt caaaggcgtt gagaccagtt gcgccaacga ggatgaggtc cacttcctcg
     8521 gcatctggaa tagtacgtgc tagcagggtc tttggatttc ccatttcaat gacgatatga
     8581 acatctgcta ccccagcatc tttagcacgt ttttcgtact ctttcatcag actttcagcg
     8641 tcgacttgga gttcttcgta aacttcagca tcaaaggtgg atacgctttg gagagcgcgt
     8701 gtgtcaatga catgtgcgat ggtgagttta gcgtcgtttc gtagagcaga atgaactccc
     8761 ttgacaaaag ccaagtccgc ttccttagaa ccatcgattg cgaccatgat attttggtaa
     8821 cgttgtgcca taatgaaacc tcctgaaatt ttcttactat aattgtaaac cttttcacta
     8881 tagaagtaaa gcaaaaaaaa gtatttttca aaagaatatt agggtttaaa ctctatataa
     8941 atatatgata aaataaaaga aaggatagca ggaaagaagt gaaggaaggg agaatgatga
     9001 aaaactcttt tcaaaaatca aatttccttt attatggaat tatcctagtt tcagtcttgg
     9061 tagaagtgat catgatctgt caattagaga gtctggtacc gcttctttat ccaagtttta
     9121 ttggattttt agtctttcat gtactctacc atctaatctt atttctagtt gtaaaacgaa
     9181 gtgggcgttg ggattacttg atgatatggg ggcttttcct catgtttaat cttctttatg
     9241 actcctttct aggcttgctt tttctaggtt tatcttttgg tatgtgatgt gtctttgcaa
     9301 aatacctgct atctctacgt tcttaacctc gcctttagca aggtttttct tctatacgaa
     9361 actagtaaca catttcagta aacttgtcgc attctctttc tagtggtata atgttactat
     9421 cctgatgaat tgaggaaaca agatgaaaga atataacaag tctagtaagt tagagcatgt
     9481 tgcttatgat atccgtggtc ctgtattgga agaagccatg cggatgcgag cgaatggaga
     9541 aaagatttta cgtctgaata caggaaatcc agcagaattt ggctttacag cgccagacga
     9601 ggtcattcat gacttgatta tgaatgcgcg tgatagtgaa ggctattctg actccaaagg
     9661 gattttctca gcccgtaagg ccatcatgca gtattgccag ctgaagaaat tcccaaacgt
     9721 agatattgat gatatttacc ttggaaatgg tgtcagtgag ttgattgtca tgtccatgca
     9781 ggggcttttg gacaatgggg atgaggtctt agtgccaatg ccagactatc ctctatggac
     9841 ggcggctgtc agcctagctg gaggaaatgc cgttcactat atctgtgatg aagctgttga
     9901 atggtaccca gatattgacg atatcaagtc aaaaatcact tccaatacca aggcaatcgt
     9961 ccttatcaat ccaaataacc caactggagc cctttatcct aaggaactct tgctggagat
    10021 tattgagatt gcccgtcaaa acgatttgat tatctttgcg gatgaaatct atgaccgcat
    10081 ggtaatggac ggacatgtgc atacgcctgt ggcgagcttg gcaccagatg tcttctgtgt
    10141 cagcatgaat ggtctgtcaa aatcccaccg catagcaggt tttcgtgtgg gttggatggt
    10201 cttgtctggc cctaagactc atgttaaggg ctatatcgaa gggctcaata tgctgtccaa
    10261 tatgcgcctt tgctctaacg ttttggccca acaagtcgta caaacttcct tgggggggca
    10321 ccaatcagtc gatgaattgc ttcttcctgg tggacgaatc tacgagcaaa gaaatttcat
    10381 ctataatgcc attcaagata ttccaggttt gtctgccgtt aaacccaagg cggggctcta
    10441 tatcttccca aaaatcgacc gcaatatgta ccgtatcgat gatgatgagc agtttgtcct
    10501 tgatttcttg aagcaggaaa aggttctctt ggttcatggt cgaggcttta actggcagga
    10561 gccagaccac ttccgtatcg tttaccttcc tcgtgttgat gagttagccc aaatccaaga
    10621 aaagatgact cgtttcttga aacagtatcg tagatagggc ttgcattcga aaaagctgga
    10681 aacatttgcc tagagctatt gacaaaagtg aaagaatcag atagaatagt aaagtatgtt
    10741 tagtaactga tcactttata gccggctaaa cgaatacaaa atctatgagg aggtattcat
    10801 cgtgaaacgt acttatcaac caagtaaact tcgtcgtgcg cgcaaacacg gattccgtaa
    10861 ccgtatgtca actaaaaatg gtcgtcgcgt attggcagct cgtcgtcgta aaggacgcaa
    10921 agttttggct gcataatcca aacgaattct atcaaaaatc agtaggaact cgagtctact
    10981 gatttttatt tttgtaaaaa agttcagtag atgcaaatgg attcggaagc gatgttacag
    11041 tagattgaaa ctagaatagt acacctctgt ttctaaaaca ttgttagaaa tcgatttgac
    11101 tgtcctgatc gatttgtcct gttattattt tattttacta taaagttgaa gtaggtggag
    11161 atggtacagc aacaatcaca ttcccagatg gttcagtagt gacgattcta ggaaaagata
    11221 cagttcaaca atctgcgaaa ggtgaatctg taactcaaga agctacacca gagtataagc
    11281 tagaaactac accaggtgga gataagggag gcaatactgg aagctcagat gctaatgcga
    11341 atgaaggcgg tggtagccag gcgggtggat cagctcacac aggttcacaa aactcagctc
    11401 aatcacaagc ttctaagcaa ttagctactg aaaaagaatc agctaaaaat gccattgaaa
    11461 aagcagccaa gaacaagcag gatgaaatca aaggcgcacc gctttctgat aaagaaaaag
    11521 cagaactttt agcaagagtg gaagcagaaa aacaagcagc tctcaaagag attgaaaatg
    11581 cgaaaactat ggaagatgtg aaggaagcag aaacgattgg agtgcaagcc attgccatgg
    11641 ttacagttcc taagagacta gtggctccta atgctgctcc taagacaaca agtgcaccgc
    11701 aagcaactgc aggaacaatg caaaatgtta cctaccagtc acctgctggc aaacaattac
    11761 ctaacacagg ttcagcatca agtgcagcac ttgctagtct tggtctagtg gtggcaacaa
    11821 gtggttttgc tttgctagga agaaagacta gacgtagaaa atagaacagc tagaaaattc
    11881 tattctctac ttaaagttag attataaggg ggattttgag aagtcatcaa tcctagtgat
    11941 gggtgagaaa agtgagaacc caagataatc acatacttta gctgaatagg aatattctat
    12001 caatgtagcc aatctcttct gtctctaact gtggaatagg agataggcaa tatcggatag
    12061 aaaagatagc agaatagctc tctattgaag agaggagggg aaaccgaaaa attaggtgcc
    12121 cctcctcttt tttggtataa tagaagatag aaaacgaggt tagaagagat gatttttgat
    12181 acacatacac acttgaatgt agaagaattt gcaggtcgtg aggcagaaga aattgccttg
    12241 gctgctgaga tgggtgtgat acagatgaat attgttggtt ttgataaacc gacgattgag
    12301 cgtgccttgg agttggtaga tgagtatgag cagctctatg cgactattgg ttggcatcct
    12361 acagaagctg gtacttatac agaggaagtt gaggcttact tgttggataa gttaaaacat
    12421 cccaaggttg tggctttagg tgaaattggc ttagactacc attggatgac agcgcccaaa
    12481 gaggtgcagg agcaggtttt tcgccgtcag attcagctat ctaaggactt ggatttgcct
    12541 tttgttgtcc atacccgtga tgcgctggaa gatacctatg agattatcaa gagtgagggc
    12601 gttggtcctc gtggtggtat catgcattca ttttcaggga cgcttgagtg ggcagagaag
    12661 tttgtggatc ttggtatgat catttccttc tcaggagtgg tgactttcaa gaaggcaact
    12721 gacctccaag aagcagctaa agagttacct ttggacaaga tgttggtgga aacagatgcg
    12781 ccttacttag cacctgtacc caagcgtggt cgtgaaaata aaacagccta tactcgctat
    12841 gtggtcgact ttatcgctga cttgcgtggt atgacgacag aagagctggc ggtagcaacg
    12901 actgcaaatg cagaacgaat ttttggattg gacagcaagt aatgaaagag aaaatttctc
    12961 aagttatcgt ggttgaaggt cgctatgata cggtcaatct caagcgttat ttcgatgtgg
    13021 agacctatga gacacgaggt tctgccatca atgatcagga tatagagcga attcagcgtc
    13081 tacaccaacg tcatggagtc attgtcttta cagacccaga ttttaatggg gaacggattc
    13141 ggcgcatgat catgacggtc attccaacag ttcagcatgc ctttctcaag cgagatgaag
    13201 ctgttcccaa gtccaagacc aaggggcgtt ctctgggaat tgagcatgcc agctatgaag
    13261 acctgaaaac ggctctagct caggtgacag aacaatttga acatgagagt cagtttgaca
    13321 ttagtcgtag cgatttgatt cgccttggtt ttctagcagg ggcagacagc cgtaagcgta
    13381 gagaatatct cggagagact ctccgaatcg gctattccaa cggcaagcaa ctcctcaaac
    13441 gcctagagtt gtttggggtt actttggcag aagtggaaga agctatgaaa tcttatgagt
    13501 aggaaagatg tagccgttac aattttttaa gtttcacagt atttttcgaa gcaggtagaa
    13561 gaggaggcgt ctgatgttaa ttggtcaaaa aattaaagag attcggatag aaaaaggaat
    13621 tagtcgtcca gatttttgtg gagatgagca agaactgaca gttcgtcaac tgtcgcgaat
    13681 tgaaagtgga gcttcgcaac cgagtttgcc caagttagac tatattgctc gccggctagg
    13741 agttccagtt tatagcctta tgccggattt ttcagctctt cctcctgctt atttagaatt
    13801 gaaataccag attttacgtg aaccaatcta tggtaaagaa gaggagtacg ataagaagga
    13861 agcgtgtttg gaagagattt ataaaacata ctttgataat cttcctaaag aagaacaatt
    13921 agcatgtgaa gtattgcagg cgtgtttgga tacttctaga actagaaggc ctgaatatgc
    13981 agagttaata cttgaggaac atatgtctca gatcatagaa aaagaagttt attcaacaaa
    14041 tgatatgttg ttgattcgtt tgttttttta tcaaatgctc attagaaaag atcttgccaa
    14101 atttataaat caaatcgaaa agctaatgct ctttcttttg gaacagaaaa aggtaactaa
    14161 attagaaaac ttctttataa ttagagatac tcttatttca ggaatgtgtt gtcttgaaaa
    14221 ggtaggagta actgattgtt ttaatgatta tctatcgtgt ttacaagaaa ttatggataa
    14281 aactcaagat tatcaaaaga aacctcttgt atttatgttt ttgtggaagc aagcattaag
    14341 agaagaaaga gattttagtt tagctgaatc attttatcag tcttctaaaa catttgcgaa
    14401 gctaattgga gatggatttc tagtaaagaa attgacagag gaatggcaag aggatgtcaa
    14461 aaaatattta taaacatagt gaatcagtga caaaaatgtc cttgtcctcg tatcaaaaca
    14521 gttctaaagt tcgtctttag aactgttttt ttagatataa gctaaaaata atatgaaata
    14581 gttagatttt aaggacattg atgtccttga tagtgtgata aagatggagt ataatgacta
    14641 taaaagttca tttcagggtg ctattttgac aatttagaga aaaacaaata attttagaat
    14701 atcatttggt aatataatag tatcaacgtt gataatggaa agaggagcaa gtaactcaac
    14761 aatcttgtaa tcaaaaatag aggagtatca atatgaaaca aacagttaaa aagttagctc
    14821 ttgtagcgag cattgcagca acattaggtg gaggtgtatc agttgcctct gcagccgttc
    14881 aatacccaga aggtggtgtt tggacttatg gttcaggtaa cggtggtgct tactcaaact
    14941 actatcaccc ttcaaaatac catagttcaa cagttgttag cagaaaaact ggttcatctg
    15001 acaagggata tgctggtgct ggagggactt ctcgtgcatg gattcgtact tcttggggag
    15061 agaaagttgc attctactat aatgtttaga atggtatagc cctattgttt agctttactt
    15121 ggtcaccttc tcactaagtg accaagtaac tttttggagg aaatgatgaa acgtttattt
    15181 attttgattt caatggtatt ggtatcgctt tatatggtga taacttccgt tgaccatcga
    15241 gaagagattt tatttggtaa ctatccttct gttgatgtga caggaatgat gataaatcaa
    15301 ccagtagcta gtcgcgaaga ggtgacagag gctttgagtc acttggcggt agagcataat
    15361 agtctcatcg cccgtcgaat cgttgagcca aatgaagctg gagaaacact ctttacctat
    15421 gccacttatg gtgagggaga gcttccagaa ggtctgacca tttcctccaa ggagagtgca
    15481 gaaacgagtg atttattagg gtcttacttg attgtgtcag gaagtttgga tggagtgagc
    15541 ttacagacca ccttgaaaga acttggctat caaggctttg tttcgaatgg agaagatcca
    15601 ttttcgatag tcttactatt gacggccacc cctatggtgc tactgagttt agctattttt
    15661 ctgctgacct ttatgagtct gaccctgatt tatcggatca aatcccttcg tcaggcaggg
    15721 attcgcttaa tagctggtga gagcttgttt ggagttgctc tcagaccagt gttagaagat
    15781 gtgagacagc ttatctgctc agtgctggta tccagtcttt tgggattggg gattctctgg
    15841 tatcaaggtg ccttgtttat ggcaacggtg caactggtca tcattgctct tctactttat
    15901 ggattgaccc tggcagggat ttctacctta ctaagtgtcg tctatctact tggtttacag
    15961 gaaaatagtc tggtggatct attgaaaggg aaactccctc tcaaacgtat gatgacattg
    16021 atgatggtgg ggcaactctt agctgtattg gtggtcggat cgagtgcgac agctctccta
    16081 ccccactacc gtgaaatgca ggaaatggag agagctagca ataaatggag ccagtcctca
    16141 gaccgttacc gtctatcctt tggttggtct agtgcatttg ccgatgaaga aggaacgcgt
    16201 aaggataatc gtgagtggca gacatttact gaagaacggt tagccaatac agactctttt
    16261 tatattatga gcaatgttga caatttctca gatggagcag aagtggacct agatggcaat
    16321 cgtctcagtg actacacacc gtcagggaat gttatctatg tctcaccacg ctatctgata
    16381 gaagaaaaga ttaccgtttc ttcagagttt atggacaaga tgcaaaactt gtctgaggga
    16441 gagtttgggc tgatcttgcc tgagagcttg cgagagcagt ctacctacta ccaaggattg
    16501 tttacagatt acctgcaaaa cttttcatct gaaagtgtag aagtgacgag tcagaaatac
    16561 tacctcccac aggtaaggct agcttttaca gaaacaggac aggaacgttt cctctataat
    16621 gatgggtaca agacaacacg ccagtaccta aaagatccga ttattgtagt tctaacgccg
    16681 caagcgactg gaacaagacc tgttgcaggg atgttgtggg gaactacggc taatagtgcc
    16741 ttgaaactag atcgatatgg agacagcatc acagctctaa aagagcaagg tctgtatcac
    16801 aaggtttctt acttggtaaa aagccagcta ttttttgcca aggtactaaa tgacaaacgg
    16861 gtggagtttt actctctcct tattgggacg attttgaccc tgtctacggc tatcttgtta
    16921 tttgattcca tgaatcttct ctattttgag cagttcagac gggaacttat gattaaacgt
    16981 cttgctggta tgacaatcta tgagcttcat ggcaagtatt tactggcgca aggaggagtt
    17041 ctcttgcttg gcctagtcct atctagtatt ttgacaagag attgtttgat tagcgctcta
    17101 gttgtagctt tgtttacgct taacgccctc ttgattttag taaggcagga caaaaaagaa
    17161 gaagctggta gcatggcagt attgaaagga aaataagatg attgatattc aaggattgga
    17221 aaagaaattt aatgaccgcg cgattttctc tggtttgaat ctcaagctgg agaagggcaa
    17281 ggtttatgcc ttaatcggaa agagtggaag cggaaagacg acgctgctga atatcttggg
    17341 aaagctagaa aagatagatg gtggaagggt tctctatcag gggaaagatt taaaaaccat
    17401 tcccactcgt gagtattttc gagaccagat gggctatctc tttcaaaatt tcggcctctt
    17461 agaaaaccaa tcaatcaaag aaaatttgga tttgggtttt gttggtcaga aaatctcaaa
    17521 agtagaacgt ttggaaaggc aagtgggggc tttagaaaaa gttaatctag ggtatttgga
    17581 tttagaacaa aaaatctata ctttatctgg gggagaggcc caacgagttg cccttgctaa
    17641 gactattttg aaaaatccac ccttgatttt ggcagatgaa ccaacagcag ctcttgatcc
    17701 tgaaaattca gaggaggtta tgaatctctt ggtggatttg aaagatgaaa atcgaattat
    17761 catcattgcg acccataatc ccctagtctg gaataaggct gatgaaatca ttgatatgag
    17821 gaaacttgct catgtgtgaa aaaatccgta ttcgcagggt atctgattat cctagtgcca
    17881 gaggtggttt agaagatatc ctcatcatgg aaaatatgac caatcatctc cttttggttc
    17941 aaatccgagt gcatggctat ttgcttgatt ttgctagtat tgaagggcaa aggcaaaagc
    18001 attatcgttt gaaaaattta cctcagacgg ttgaactgac agtggatgat gtggaggagg
    18061 atgtggattt gaccctaccc gaaaatcgaa gttatcaaga agctgatttt tttgatactc
    18121 aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc tgtacttgag tacggcaagg
    18181 tgaagctgac gtggtttgaa gagattttcg aagagtatga acgtatgttt cgagagaagc
    18241 actaagtccc tctttaaaga tttccaagac tatctttctt catgaggaaa gatagttttt
    18301 tggtatgatt ttcattccca aaatacaagg ggaatgtgtt acaatagtag taacagataa
    18361 tagaaaagag aatagatgag aattgcagat tatagcgtga ccaaggcagt gttggagcgt
    18421 cacggtttta cctttaaaaa gtcctttggg caaaatttct tgacggatac caatatcctt
    18481 caaaaaattg tggatacggc tgaaattgat gatcaggtca atgtcatcga aatcgggcca
    18541 ggtattggtg ccttgacaga atttttggct gagcgtgcag cccaagtcat ggcttttgag
    18601 attgaccacc gtttgatgcc aattttggca gatactctgc gtgattttga taatgtgacc
    18661 gtagttaacg aagatattct caaggttgat ttggcgcaac atatccaaaa ttttaaaaat
    18721 cctaacctgc caatcaaggt agtggctaat ttgccttact acatcacgac gcctattctc
    18781 atgcacttga ttgagagtgg cattcctttt tgtgagtttg tggtcatgat gcagaaagaa
    18841 gtagcggacc gcatttcagc ccagcctaac accaaggctt acggtagctt gtctatcgcc
    18901 gtgcagtatt acatgacagc caaggttgcc tttatcgtgc ctcgtacggt ctttgtgcca
    18961 gcgccaaatg tggattcagc catcttgaaa atggtgcgtc gtccagagcc agccgtagca
    19021 gtagaagatg agaacttttt ctttaaggtt tccaaggcta gttttaccca tcgccgcaag
    19081 accttgtgga ataacttgac aggttacttt ggtaagactg aagaggtcaa ggacaagctg
    19141 accaaggctt tggaccaggc aggcttgtca ccaagtgtgc gtggggaagc tctcagcttg
    19201 gcagaatttg ccggtctagc agacgcactt aaagggcaag gactctaaga tgcagggaca
    19261 aatcattaaa gccttggcag gtttctacta tgtggagagt gatggccagg tttatcaaac
    19321 acgcgcgcgt gggaatttcc gtaaaaaagg ccatacccct tatgttgggg actgggtaga
    19381 tttctctgcc gaggaaaatt cagaaggcta tatcctcaaa attcacgaac ggaaaaacag
    19441 tctggttcgt ccgcctattg tcaatatcga tcaagctgta gtaatcatgt ccgtcaagga
    19501 acctgatttt aacagcaatt tgctggatcg tttcttggtt cttttggagc acaagggcat
    19561 ccatcccatt gtctatattt ccaaaatgga tttgttggaa gataggggag aactggattt
    19621 ttaccagcag acctatggtg acatcggcta tgactttgtg accagtaaag aggaactcct
    19681 gtctttgtta acaggcaagg ttacggtctt tatggggcag acaggtgttg ggaagtcaac
    19741 tcttctcaat aaaatcgcac cagacctcaa tcttgaaacg ggagaaattt cagacagtct
    19801 aggtcgcggt cgccatacca ctcgagctgt tagtttttac aatctcaacg ggggtaaaat
    19861 cgcagataca ccaggctttt catctctgga ctatgaagta tcaagggctg aagacctcaa
    19921 tcaggccttt ccagagattg ctactgttag ccgagattgt aagttccgta cttgtaccca
    19981 tacccatgag ccgtcttgtg ccgtcaaacc agctgttgaa gagggtgtta ttgcaacctt
    20041 ccgttttgac aattacctgc aattccttag tgaaattgaa aatcgtagag aaacctataa
    20101 aaaagtcagc aaaaaaattc caaaataagg agaaacctat gtctcaatac aagattgctc
    20161 cgtcaattct ggcagcagat tatgccaact ttgaacgtga aatcaaacgt ctagaagcaa
    20221 ctggggcaga atatgcccat atcgatatca tggacagtca ttttgtaccg caaatcagtt
    20281 ttggtgcagg tgtggtcgag agccttcgtc ctcatagtaa gatggttttc gattgccact
    20341 tgatggtgtc aaaccctgag catcatctgg aagattttgc gcgtgcaggt gcagacatca
    20401 tcagtatcca tgtagaagca acgcctcata ttcatggcgc cctccaaaaa attcgttcac
    20461 tcggagttaa gccttcagtc gttatcaatc ctggcacacc agttgaagcc atcaagcacg
    20521 tccttcatct agttgaccaa gttttagtca tgacggttaa tccaggtttt ggtgggcaag
    20581 cctttctgcc agaaaccatg gataaggttc gtgagttggt tgctcttcgt gaggaaaaag
    20641 gtttgaactt tgaaatcgaa gtggatggtg ggattgatga ccaaactatt gctcaagcca
    20701 aagaagctgg tgcgactgtt tttgtagcag gttcctatgt ctttaaggga gaagtcaatg
    20761 agcgagtaca aactctcaga aaacaactgg actagggttg cagtttttgc aggcggaaac
    20821 cgcggtcatt atcggacaga ttttgatgct tttgttgggg tggatcgagg ctcgctctgg
    20881 gtcttggaag aagacttacc tcttgctcta gcagtcggag attttgattc tgtgacggaa
    20941 gaagagcgac aggtgattca aaaacgtgcc cagtattttg tccaagcccg accagaaaaa
    21001 gatgataccg atttggaatt ggctctctta accatctttg agaaaaatcc tcaggctcag
    21061 gttactattt tcggtgcctt gggtggccgt attgaccata tgttggccaa tgtctttctg
    21121 cctagcaatc ctaagttggc accctatatg catcaaatag aaattgagga tgggcaaaac
    21181 ttgattactt attgtccaga agggaccagt cagctagaac ctcgttcaga ctacgactat
    21241 ctagccttta tgccagttcg ggatagccag ctgactattc ttggagccaa gtatgagttg
    21301 acagaggaaa attttttctt taaaaaagtg tacgcttcta acgaatatat agatagggaa
    21361 gtgtcggtaa cttgcccaga tggttatgtg gtcgtactgc atagcaagga taggaggtag
    21421 gatggaaagt ttacttattc tattattaat tgccaaccta gctggtctct ttctgatttg
    21481 gcaaaggcag gataggcagg agaaacactt aagtaagagc ttggaggatc aggcagatca
    21541 tttgtcagac cagttggatt accgctttga ccaagccaga caagccagcc agttagacca
    21601 aaaagatttg gaagtggctg tcagcgaccg tttgcaagaa gtgcggattg aattgcacca
    21661 aggcctgacc caagtccgtc aagaaatgac agataatctc ctccaaacta gagataagac
    21721 agaccaacgt ctccaagcct tgcaggaatc aaatgagcaa cgtttggaac aaatgcgcca
    21781 gacggtcgag gaaaaactag aaaagacctt gcagacacgc ttacaggctt cctttgagac
    21841 agtttctaaa caactggagt ctgtcaatcg tggtcttgga gaaatgcaga cagttgcccg
    21901 tgatgtcgga gctcttaaca aggttctctc tggaaccaag acgcgaggga ttctgggaga
    21961 attgcaactg gggcaaatta ttgaagacat catgacacct gcccagtacg aacgagaata
    22021 cgcaacggtt gaaaactcta gtgaacgagt ggagtatgcc atcaagttac ccggacaagg
    22081 cgaccaagaa tacgtctatc ttccaattga ctctaagttt ccactggcag attattaccg
    22141 cttggaagaa gcctatgaga caggtgacaa ggatgagatt gaacgctgtc gtaagtcact
    22201 cctagcaagc gtcaagcgct ttgccaagga tatcaagagc aagtacatag caccgcctcg
    22261 gacaaccaac tttggaatct tgtttgttcc gacagaaggt ctttattcag agattgtgcg
    22321 caatccggtc ttctttgatg atttgagacg ggaagaacag attattgttg caggaccaag
    22381 taccctatca gcccttctta actccctatc agttggtttc aagaccctta atatccaaaa
    22441 gagtgccgac catatcagca agactcttgc cagtgtcaag accgagtttg gcaagtttgg
    22501 tggtattctg gtcaaggcac aaaaacatct ccaacatgcc tctggcaata ttgatgaatt
    22561 attaaaccgt cgtaccatag ctatcgagcg gacgctccgt cacattgagt tgtcagaagg
    22621 tgagcctgcg cttgatctac tctattttca agaaaatgag gaagaatatg aagattagtc
    22681 acatgaaaaa agatgagtta tttgaaggct tttacctaat caaatcagct gacctgaggc
    22741 aaactcgagc tgggaaaaac tacctagcct ttaccttcca agatgatagt ggcgagattg
    22801 atgggaagct ctgggatgcc caacctcata acattgaggc ctttaccgca ggtaaggttg
    22861 tccacatgaa aggacgccga gaagtttata acaatacccc tcaagtcaat caaattactc
    22921 tccgcctgcc tcaagctggt gaacccaatg acccagctga tttcaaggtc aagtcaccag
    22981 ttgatgtcaa ggaaattcgt gactacatgt cgcaaatgat tttcaaaatt gaaaatcctg
    23041 tctggcaacg gattgtccga aatctctaca ccaagtatga taaggaattc tactcctatc
    23101 cagccgccaa gaccaaccac catgcctttg aaacgggctt ggcttatcat acggcgacca
    23161 tggtacgttt ggcagacgct attagcgaag tttatcctca gctcaataag agcttactct
    23221 atgcggggat tatgctgcat gacttagcta aggttatcga gttgacgggg ccagaccaga
    23281 cagagtacac agtgcgaggt aatcttcttg gacatatcgc tctcattgat agcgaaatta
    23341 ccaagacagt tatggaactc ggcatcgatg ataccaagga agaagtcgtt ttgcttcgtc
    23401 atgtcatcct cagtcaccac ggcttgcttg aatatggaag tccagtccgt ccacgtatta
    23461 tggaggcaga gattatccat atgattgaca atctggatgc aagcatgatg atgatgtcaa
    23521 cagctctggc tttggtggat aaaggagaga tgaccaataa aatcttcgct atggataatc
    23581 gttccttcta taaaccagat ttagattgat aatttaagaa aaatgagcat tttttaggat
    23641 aagaatgttc gtttttttat gtgaatatgg tataataagt aaaagacaaa aatgaatact
    23701 cttcgaaaat ctcttcaaac tagggtagta tcgccttgtc gtatgtatat atgcaggtat
    23761 attacagggt ttgtcagttc tatcgacaat ctcaaagcag tgttttgaac caccagcgac
    23821 cagctttcta gtttgctttt tgattttttg aataaaaatg gaataggaaa tagaaatgaa
    23881 attaagaaga agtgatcgga tggttgtcat ttccaactat ttgattaata atccttataa
    23941 actaactagt ctcaatactt ttgctgaaaa gtatgagtct gctaaatcat ccatctcaga
    24001 agatatcgtc attatcaaac gcgcctttga ggaaattgaa atcggtcata tccagacagt
    24061 gactggggct ggcggaggtg tcatcttcac accgtctatt tcgagtcagg atgctaagga
    24121 aatggttgaa gacttgcgta ccaagttgtc agaaagtgac cgtatcttgc caggtggtta
    24181 tatctatctg tctgatttgc ttagcacacc agccatcttg aaaaatattg gtcgtattat
    24241 tgccaaaagc tttatggacc aaaaaattga cgcggttatg accgtagcaa ctaagggtgt
    24301 gccacttgca aatgcagttg ccaatgtcct caatgtctct tttgtcattg tgcgccgtga
    24361 cctgaaaatt accgaaggtt caactgttag cgtcaactat gtttcaggtt caagtggtga
    24421 ccgtatcgag aaaatgttcc tttcaaaacg tagtcttaag gcaggtagcc gtgtcttgat
    24481 tgtggatgac ttcttgaaag gtggcggaac ggtcaacggt atgattagtc tcttgcgcga
    24541 gttcgactca gaactggcag gtgtagcggt ctttgcggac aatgcccaag aagaacgtga
    24601 aaagcagttt gactacaagt cactcttgaa ggtaactaat attgatgtca agaaccaagc
    24661 catcgatgtt gaggttggca atatctttga cgaagataaa taagagatag aactaaaggt
    24721 tggaacgatt gtcccagcct ttctttgcaa acagaataga aggaagctta tgaaaacacc
    24781 atttatcaat agagaagagt tagaagcgat tgttgccgag ttcccgactc cctttcactt
    24841 gtatgatgag aaggggattc gtgagaaggc aagagccgtc aaccaagctt tttcgtggaa
    24901 caagggcttt aaggaatatt ttgcagttaa ggctactcca actccagcta ttttgaaaat
    24961 tctccaagaa gaaggttgtg gtgtggactg ctctagttat gtagagcttt tgatgagcca
    25021 taaactggac tttctgggtt ctgagattat gttctcttcc aacaacacgc cagacaagga
    25081 atacgcctat gcacgtgaat tgggtgcgac cattaacttg gatgcctttg aagatattga
    25141 acatctggag agagtagcag gcattccaga aatcatctct tgtcgttata atcctggagg
    25201 cgtttttgaa ctggggacag acattatgga caatcctggg gaggctaagt ttggcatgac
    25261 caaggaccag ctctttgaag cctttgctat cttgaaggaa aaaggagcca agacttttgg
    25321 gattcactcc ttcctagcgt ccaataccgt gacccatctc tattatccag agttggctcg
    25381 tcagctcttt gaactggctg ttgaaatcaa ggaaaagttg ggcatttggc tagactttat
    25441 caatctttct ggcggtattg gtgttaatta tcgtccagac caggagccga acgatatcgc
    25501 cttgattggt gagggagttc gtaaggtgta tgaagaagtt cttacgtcag caggtcttgg
    25561 tcaggtcaag attttcaccg aattgggtcg ttttatgctg gcacctcacg gtgctctagt
    25621 cacaagagtg actcataaga aggaaaccta ccgtacctat ctaggtgtgg atgcctcagc
    25681 agtcaacctc atgcgtccag ctatgtacgg agcttaccat catattagca acgtgaccca
    25741 tccagatgga ccagctgaag cggtagatgt ggttggttca ctctgtgaaa acaatgataa
    25801 atttgcagtc aatcgcgaac tgcctcatac agaaatcggt gatttgctgg taattcatga
    25861 tacaggtgcc cacggatttt caatgggcta ccagtataat gccaaattac gttctgcgga
    25921 aatcctctat accgaagaag gtaaagcccg tcaaatccgc cgtgcagagc gccctgagga
    25981 ctattttgca accttatatg gcttcgattt tgaagaataa tctgataata gattgaaaat
    26041 gaaattgaaa aacagattgc tttctaaaaa ataggcaaaa atcttgtttt tccttcaagt
    26101 cgtgatataa taaaactata aaacgttttc aaggaaggta acgatatgtc tgaagaaaca
    26161 attgattatg gacaagtgac aggaatggtg cattcgacag aaagctttgg gtcagtagat
    26221 gggcctggta ttcgctttat tgtctttttg cagggctgtc acatgcgttg ccagtattgc
    26281 cacaacccag acacttgggc tatggagtcc aataagtcac gtgaacggac ggtagatgat
    26341 gtcttgacag aggccttgcg ctaccgtggt ttctggggaa ataagggtgg gattacagtc
    26401 agtggaggag aagctctctt gcagattgat ttcctgattg ctctcttcac caaggctaag
    26461 gaacaaggaa tccactgtac cttggatacc tgtgctcttc ctttccgtaa taaaccacgt
    26521 taccttgaga agtttgacaa actcatggct gtcactgact tggttctttt ggatatcaag
    26581 gaaatcaacg aagaacagca caagattgtc actagacaaa ccaataaaaa tatcttggct
    26641 tgtgcccagt atctatcaga tattggaaaa cctgtctgga ttcgccacgt gctagttcca
    26701 ggattgacag acagagatga tgacttgatt gaacttggta agttcgtcaa gaccctcaaa
    26761 aatgttgata agtttgaaat tctaccttat cacaccatgg gtgagttcaa gtggcgtgaa
    26821 cttggaattc catattccct cgaaggagtc aaaccaccaa cagcagatcg cgtcaagaac
    26881 gctaaaaaac tcatggatac cgaaagttat caagattata tgaaacgtgt acatggatag
    26941 aaaagaagcc tgatggaaac atcgggcttt tgatttgcaa aaagacttag caaatcagct
    27001 aagccttttt cttcttatct cgaacgttgt tttccagcgt tgcgattttt gtgttttttc
    27061 ttgcttgtga tagcagttgg ttgttcaggg gtaacgtctt ttcgtccact tggtttagag
    27121 aaagcacttg cttttggtgg gttcttggct agttcttcac ggactttttt gcgaagtttt
    27181 ggacgaacga tatagttgac gataaactgt tggagaatca tcatgaaacc accgacaacc
    27241 cagtaaagtg tgacactagc tggtgagaag agggagaaga cgacgatcat gagtgggctc
    27301 atgtaaatca ttttcttgat ttgttctctt tgcatttcat cttctactcc gtgaagtgaa
    27361 aggagcgatt gaagatagta aaggacacca gcacaggcaa ccaaaatcat acttggagaa
    27421 cctagaggaa tgcctaggta gcttgcttga gcaacccctt cagtatgttg ggcagcaaag
    27481 tagatagcag agaagaaagg catttgaagg aggataggga aacatcctac accgccaaac
    27541 atgctgatac cgtgctcttt ttgagcagca aagagagctt gttgggcttc gagtttttct
    27601 tcttgagtag tcgcttcttt gagacgcgtt tggtgtggct caaggacgtg cttgagggcg
    27661 ttcatctttt cagagtgaag cgttgccttc catgattggt agataccaag tggcaagata
    27721 atcaagcgca cgataatggt tacgatgatg atagcgacac caaagcctag acctttatca
    27781 gtagcgaagt acttgatagc ttcagccata ggggctccga tggtattcca aataaatcct
    27841 gttggctgac ctgtggtttt atcgacattg acacaaccag tcaagacaag caacatagcc
    27901 gctcccatag ctgagagtgc aaaacgttta atagatttca ctgtttttat tccttcttta
    27961 aaaattatac ctttctattc tactgttttt ttacaaaata tacaatagtt ctggagacct
    28021 aatttgcgat tttaaagtca gagtagggag gaaagttgct tagtttgaca tctaagtagc
    28081 ttacttttga aaaaggtgtc ggtccttttc ggatttcttg gataaatttt gccatgatag
    28141 cagatgagtc tgcttgggct aagatttcca ctgtgccatc gtcgttattc catactcgac
    28201 ctgtgatgcc accaatttca agtgccaagc tgtaaacacc ccaacgaaag ccgactccct
    28261 gtaccctacc ttgggcaatc attctaacct tttgcatacc aaaccccttt gattgtgtta
    28321 taatatttct atgactatta taacctcaaa agccaattct gtggtaaaaa atgccaagaa
    28381 attacgccaa aaaaaatacc gcaagtctgc ctacttgatt gaaggctggc acttgtttga
    28441 agaagctgtc caagctggag tgacgattga gaaaatcttt gccctagaaa attatcgaga
    28501 tcagttagct actttttcgc aaactgtctg ggtgtcagag gatattttgc tagatttggc
    28561 ggattctcag actccacagg gaattgttgc cgtggttcaa aaagaagaag taggacaagc
    28621 tgatttgagt cagggcaagt tcttgttttt ggaagatgtg caagatcctg gtaatgtagg
    28681 aactatcatt cgaactgcgg atgcagcagg ttttacagga gtgattgttt cagataagtc
    28741 ggcagacatc tacagtctca aaaccctacg ttccatgcaa ggtagtcatt tccatctgcc
    28801 catttaccgg atgactagtc aagcgcttct tgacgaaact aaaaaggtag ctatcccagt
    28861 gctagcaaca accctatcta aagattctgt tgattacaga gaactgcctt ctatagaaaa
    28921 ttttgtacta gttatgggaa atgagggtca aggaattagt ccccttatgg ctgaaagtgc
    28981 agaccagttg gtccatatta gcatgaaggg gcaggccgag agtttgaatg ttgcggttgc
    29041 agccggtatt ttaatcttcc atttaagcta attttaactt tttttgttat aatcaaggaa
    29101 agatgttcac agaaaaggag aaatggatga atcacactat tatacatgac cgtgcaggtc
    29161 tcaatcaatt ttacgctaag gtttatgcct ttgttggtct gggaatcgga ctatctgctt
    29221 tggtatcagg ccttatgttg acggtctttc agtctcagtt ggtttacttt ttgatgcagg
    29281 ggcgtctctg gttgaccatt gctacttttg cggagttggc tttggttttc gttgccagta
    29341 gcatggcttc aagaaatagt ccagctgctc ttccagtatt tttactttac tccgttttaa
    29401 acggctttac ccttagtttt gtggtggctt tctatactcc gggtacagtt ttatctgcct
    29461 ttgtatcgag cgcccttctc ttctttgtca tggcggcagt tggtattttt accaagaaag
    29521 acttgagtgg gattggtcga gcaatgatgg cagctctcat tggtttactg attgctatgg
    29581 tagtcaatat tttcttggct agtggcttct ttgattatat gattagcgta gccatggttt
    29641 tggttttttc agggttgatt gcttgggata accaaaagat tcgcctcgcc tatgaacaat
    29701 cacaaggtcg tgtagcgaca ggctgggtgg tgtcaatggc tctcagcatc tatcttgatt
    29761 ttatcaatct tttcctaagt attctacgta tctttggtcg caatgactaa aaggtctatg
    29821 aaatcagtgt tttgagtgac actgattttt tttaaatttt ctcttttctt ttcttggaaa
    29881 taggtgtata atacgtttat taaatttttg aggagttgtc tatgaagaaa agttttatcc
    29941 atcaacaaga agaaatttcc tttgtcaaaa acacttttac ccagtatttg aaagataagc
    30001 tagaagttgt cgaagttcaa ggtcctatct tgagtaaggt cggtgacgga atgcaggaca
    30061 acctgtctgg tgtggaaaat ccagtatcgg tcaaggttct ccaaatccct gatgctactt
    30121 atgaagtggt gcactcactt gctaaatgga aacgccacac cttggctcgt tttggctttg
    30181 gtgaaggaga gggtctcttt gtccacatga aagcccttcg tccagatgag gattccttgg
    30241 atgcaaccca ctctgtttat gttgaccagt gggactggga gaaggttatc ccaaatggta
    30301 agcgtaacat cgtttatcta aaagaaacag ttgagaagat ttataaggct attcgcctga
    30361 ctgagctagc tgttgaagcc cgctatgaca tcgagtctat cttgccaaaa caaatcacct
    30421 ttatccatac agaagaattg gtagaacgct acccagactt gacacctaaa gaacgtgaaa
    30481 atgcgatttg taaagaattt ggagccgtct ttttgattgg tatcggtggc gagttgccag
    30541 atggtaaacc gcacgatgga cgtgcaccag actatgatga ctggacaagc gagtctgaga
    30601 atggctacaa gggtctaaat ggtgatattc ttgtctggaa tgagtcttta ggtggagcct
    30661 ttgagttgtc ttctatggga attcgtgtag atgaagaaac tcttagacgt caggtggaaa
    30721 ttacaggtga tgaagaccgc ttggaattgg aatggcacaa gtctttgttg aatggcctat
    30781 tcccattgac aatcggtgga ggaattggac aatctcgtat ggccatgttc ctacttcgca
    30841 agagacacat cggagaagtg caaacaagtg tttggcctca agaagtccgc gatacttacg
    30901 aaaatatttt gtagagaatc gaaccgcaag gttcggtttt ctttctcttt ttgtctataa
    30961 tttggtataa taaacagtat gaaaatcgta tcaggaatct atgggggacg tcccctcaag
    31021 acactagaag gcaagacaac aagacctact tcggataagg ttaggggagc catttttaac
    31081 atgattggtc cctactttga agggggacga gtcttggacc tttatgcagg tagtggtggt
    31141 ttatctatcg aagcagtatc gcgtggcatg tccagtgctg ttttggtgga gcgagaccgt
    31201 aaggctcaga ccatcgtggc tgaaaatatc cagatgacca aggaagttgg aaaatttcaa
    31261 ctcctcaaga tggatgcaga gagggcattg gaacaggtat ctggggaatt tgacctcgtt
    31321 ttcttagacc ctccctatgc caaggaacaa atcgtagcag atattgaaaa aatggctaag
    31381 agagagcttt tttctgaaga tgttatggtt gtgtgcgaga cggataaggc cgttgaactt
    31441 ccagaagaga ttgcctgtct gggtatctgg aaggaaaaga tttatggaat tagtaaggtg
    31501 acagtctatg tcagataaga ttggcttatt cacaggctca tttgatccga tgacaaatgg
    31561 gcatctggat atcattgaac gggcgagcag actttttgat aagctttatg tgggtatttt
    31621 ttttaatccc cacaaacaag gatttctccc tcttgaaaat cgtaaacggg ggctagaaaa
    31681 ggctttggga catttggaaa atgttgaagt cgtggcttct catgatgaat tggtggtcga
    31741 tgttgcaaaa agactggggg ctactttcct agtacggggg ttgaggaatg cggcggattt
    31801 gcaatatgaa gctagttttg attactacaa tcatcagctg tcttctgata tagagactat
    31861 ttatttacat agccggcctg aacatctcta tatcagttca tcaggtgttc gagagctttt
    31921 gaagtttggt caggatattg cctgccatgt tcccgagagt attttggagg aaataagaaa
    31981 tgaaaaaaaa gattagatgg cccttatacg tcattgcggc cttgattgtg actttcttgg
    32041 catttgtagt gcccttgcct tattatatag aggttccagg tggttcggaa gatattcgcc
    32101 aagtccttaa agtaaatgac acagaagata aggaagctgg tgcctatcaa ttcgttacgg
    32161 ttggtgttca acatgccact ttagctcata tgatttatgc ttggttgaca ccttttacag
    32221 atattcgtag tgctcaggag actacaggtg gttcttccga tgttgaattt atgcgaatca
    32281 atcaattcta catgcaaaca tcgcaaaata tggccaagta tcaaggacta aaaacagctg
    32341 gtaaggatat cgaactcaag tactttggag tttatgtttt gaatgtgacg gataattcaa
    32401 cctttaaagg gattctcaat atctctgata cagtcacagc agtcaatgat cagacctttg
    32461 atagttccaa agacttgatt gattacgtca gttctcaaaa attaggggat tccgtcaagg
    32521 tcacctatga agaggatggg caaaccaagt ctgcagaagg aaagattatc accttggaaa
    32581 atggcaaaaa tggaattgga atcggcttga ttgaccgtac agaggtaatc agcaatgtcc
    32641 caattagctt ttcaacagct ggtattggcg gcccaagtgc tggtctcatg tttagtctag
    32701 ctatctatac tcaaatagct cacccagatc ttcgtaatgg tcgtattgtt gccggtacag
    32761 gtaccattga ccgcgatggt aatgtgggag acattggagg tattgataag aaggttgtag
    32821 cttcggctag ggcaggtgct gctattttct ttgctcctga taaccctgtt agcgaagaag
    32881 aacaaaaggc gcatctggac gcgaaaaaca actaccaaac agccctagaa gcggctaaaa
    32941 caatcaagac ggatatgaaa atcgtgcccg ttaaaaccct acaagatgcg attgattact
    33001 tgaaaaacaa tccctaattt ttgagtgaag tttccaaact agcgcacaaa cagagaagat
    33061 ggtataatag tcaaatggtt caattattat tcactctaag tagtcatatg ctctttattt
    33121 atgtgagttt ttacctttta aaggatcttg ttagatggga gaaggtttta aaagtgacag
    33181 atgataatac aagaaaagtt cgtttattag tagccttttt tagcattgtc ataggctaca
    33241 tcctgagttc tttctttatt agcctgtatc atttgtggca agaagcgctt agaggattat
    33301 tataaaatca agagtaaagg aaacgagtat ggataaaatt gtggttcaag gtggcgataa
    33361 tcgtctggta ggaagcgtga cgatcgaggg agcaaaaaat gcagtcttac ccttgttggc
    33421 agcgactatt ctagcaagtg aaggaaagac cgtcttgcag aatgttccga ttttgtcgga
    33481 tgtctttatt atgaatcagg tagttggtgg tttgaatgcc aaggttgact ttgatgagga
    33541 agctcatctt gtcaaggtgg atgctactgg cgacatcact gaggaagccc cttacaagta
    33601 tgtcagcaag atgcgcgcct ccatcgttgt attagggcca atccttgccc gtgtgggtca
    33661 tgccaaggta tccatgccag gtggttgtac gattggtagc cgtcctattg atcttcattt
    33721 gaaaggtctg gaagctatgg gggttaagat tagtcagaca gctggttaca tcgaagccaa
    33781 ggcagaacgc ttgcatggcg ctcatatcta tatggacttt ccaagtgttg gtgcaacgca
    33841 gaacttgatg atggcagcga ctctggctga tggggtgaca gtgattgaga atgctgcgcg
    33901 tgagcctgag attgttgact tagccattct ccttaatgaa atgggagcca aggtaaaagg
    33961 tgctggtaca gagactataa ccattactgg tgttgagaaa cttcatggta cgactcacaa
    34021 tgtagtccaa gaccgtatcg aagcaggaac ctttatggta gctgctgcca tgactggtgg
    34081 tgatgtcttg attcgagacg ctgtctggga gcacaaccgt cccttgattg ccaagttact
    34141 tgaaatgggt gttgaagtaa ttgaagaaga cgaaggaatt cgtgttcgtt ctcaactaga
    34201 aaatctaaaa gctgttcatg tgaaaacctt gccccaccca ggatttccaa cagatatgca
    34261 ggctcaattt acagccttga tgacagttgc aaaaggcgaa tcaaccatgg tggagacagt
    34321 tttcgaaaat cgtttccaac acctagaaga gatgcgccgc atgggcttgc attctgagat
    34381 tatccgtgat acagctcgta ttgttggtgg acagcctttg cagggagcag aagttctttc
    34441 aactgacctt cgtgccagtg cagccttgat tttgacaggt ttggtagcac agggagaaac
    34501 tgtggtcggt aaattggttc acttggatag aggttactac ggtttccatg agaagttggc
    34561 gcagctaggt gctaagattc agcggattga ggcaagcgat gaagatgaat aagaaatcaa
    34621 gctacgtaat caatcgttta cttttagtca tcatagtact gattttaggt actctggctc
    34681 taggaatcgg tctaatggta ggttatggaa tcttgggcaa gggtcaagat ccatgggcta
    34741 tcctgtctcc agcaaaatgg caggaattga ttcataaatt tacaggaaat taggctggag
    34801 aaccagcctt tttctaaaga taaggagaaa tatgaacaaa aaaacaagac agacactaat
    34861 cggactgcta gtgttattgc ttttgtctac agggagctat tatatcaagc agatgcagtc
    34921 ggcacctaat agtcccaaaa ccaatcttag tcagaaaaaa caagcgtctg aagctcctag
    34981 tcaagcattg gcagagagtg tcttaacaga cgcagtcaag agtcaaataa aggggagtct
    35041 ggagtggaat ggctcaggtg cttttatcgt caatggtaat aaaacaaatc tagatgccaa
    35101 ggtttcaagt aagccctacg ctgacaataa aacaaagaca gtgggcaagg aaactgttcc
    35161 aaccgtagct aatgccctct tgtctaaggc cactcgtcag tacaagaatc gtaaagaaac
    35221 tgggaatggt tcaacttctt ggactcctcc aggttggcat caggtcaaga atctaaaggg
    35281 ctcttatacc catgcagtcg atagaggtca tttgttaggc tatgccttaa tcggtggttt
    35341 ggatggtttt gatgcctcaa caagcaatcc taaaaacatt gctgttcaga cagcctgggc
    35401 aaatcaggca caagccgagt attcgactgg tcaaaactac tatgaaagca aggtgcgtaa
    35461 agccttggac caaaacaagc gtgtccgtta ccgtgtaacc ctttactacg cttcaaacga
    35521 ggatttagtt ccctcagctt cacagattga agccaagtct tcggatggag aattggaatt
    35581 caatgttcta gttcccaatg ttcaaaaggg acttcaactg gattaccgaa ctggagaagt
    35641 aactgtaact cagtaaaaga taagcctaaa ctcctatgtc acttatggat gtaggagttc
    35701 tttttactag tttaagcagg gctagaacag gtactaagaa aaaatagtaa cttctaaaac
    35761 taacttccag tttcccacaa cctagctttt agtatgagaa aaacgcgtga aatcagtgga
    35821 aattcgtctt agactaactt ccagttttgg gagagagatg gaagttacgc taagaaaaaa
    35881 ataatatgta ttggattaaa ttttgtgata taataaagga taagatacta ttttaggaga
    35941 agaactatgg aagacccaag tagtcagaat ttgttgctac aatttgtttt attgtttatc
    36001 ttgacggtat taaatgcctt tttctcagcc acagaaatgg ccatggtttc tcttaatcgt
    36061 gcccgagttg aacaaaaggc ggaagaagga gacagacgct acatccgcct gctgaaggta
    36121 ctagaaaatc ctaaccactt tttatcaacc attcaggtag gaatcaccct gattacaatc
    36181 ttatcagggg cgagtttaac tgatactcta ggacgtgtga ttgcctcttg gcttgggaat
    36241 ggcgaaacag cacaagccgt ggcaactttt ctatccttgg catttttgac ctatatttcc
    36301 atcgtttttg gggaattata tcctaagaga atcgctctta atctaaagga tgccttggca
    36361 attcgtacag cgccggttat cattgggatc ggaaaactag tcagtccttt tgtttggctt
    36421 ttagctgctt cgaccaattt cttgagccat ttgactccta tgtcattcga tgatgcggat
    36481 gaaaagatga cccgtgatga aattgcctat atgctgacaa atagtgaaga aacattggat
    36541 gctgatgaga ttgagatgct acaaggtgtc ttttcgctcg atgaactgat ggcacgagag
    36601 gttatggttc ctcgaacgga tgcctttatg gtggatattc aggatgatag tcaagccatt
    36661 atccaaagta ttttaaaaca aaattattct cgtatcccgg tttatgatgg ggataaggac
    36721 aatgtaattg gaatcattca caccaagagt ctccttaagg caggctttgt ggacggtttt
    36781 gacaatattg tttggaagag aattttacaa gatccacttt ttgtacctga aactattttt
    36841 gtggatgact tgctaaaaga actgcgaaat acccaaagac aaatggcaat cttgctggat
    36901 gaatacggtg gtatggctgg tttggtgact ttggaagacc tcttagagga aattgttggt
    36961 gaaattgatg atgaaacgga caaagcagca atagatgttc atcagattgg cgaggatacc
    37021 tacattgttc aaggaactat gaccctcaat gatttcaata attactttaa tgttgaactg
    37081 gaaagtgatg acgttgatac tatcgctggt tattatttga caggagtggg aaccattcca
    37141 acgactgaga aactcagcta tgaattgatc agccaaaaca aacagtttat cttaaccaat
    37201 gataaagtga agaatggacg tgttaccaag gtaaaaatcc aaatcacaga agtcgaaata
    37261 gaagaagaaa cagaataaac tagaggcttt tgtcaccagg cgtgacgaag cttttttcaa
    37321 ttgatttcaa aagggaatta tgccatggaa agaactctgc cacaaactcg ctccaaaagt
    37381 ttttaaagtt atacgtattt attcgaggga aaataagaaa agcccttcaa attgggcttt
    37441 ctgttcattt gaaacctgat aaatcaagtt atagaaggcg gtagacggat ttgaaccgac
    37501 gatcaagctt ttgcagagcc gtgccttacc acttggctat accgccttaa cgtttattat
    37561 tataccttga aaatgatttt cagtcaatag ttttttcagt tttttgtacc atagcgtgat
    37621 tcgaatgtga tgccaagttt tctatgggaa aaaatttacc aaaaacctac tgaaacccct
    37681 tgaaaaatct agctaaatag ggtataatat gggtaatcat ttgtcgtagg ttttgtctga
    37741 aatattgtcc agacaaggct cacagcagtt aaatcttctg aaaaagtcag atttagctgc
    37801 tctttttgtg ctttttttca agattttgag catttgtaac agaggcttaa agattctgaa
    37861 aattcgtcaa gaggacacgg tgataagggg tttacaacca tatggcgatt agaaaagcct
    37921 gattgacaag gcttggaact tatttacaaa ggagaatcat cttggcagga catgacgttc
    37981 aatacgggaa acatcgtacc cgtcgtagtt tttcaagaat caaagaagtt cttgacttac
    38041 caaatttgat tgaaattcaa actgactcat tcaaagcttt cctagaccac ggtcttaagg
    38101 aagtgtttga agatgtattg ccaatttcaa acttcacaga cacaatggag ttggaatttg
    38161 ttggatatga aatcaaggaa ccaaaataca cgctagaaga agctcgtatc cacgatgcta
    38221 gctactcagc accaattttt gtaaccttcc gtttgatcaa taaagaaaca ggcgaaatca
    38281 agacccaaga agttttcttt ggtgatttcc caatcatgac agaaatgggt actttcatca
    38341 tcaatggtgg tgaacgtatt atcgtttctc agttggtccg ctcaccaggt gtttacttta
    38401 acgacaaagt agacaaaaat ggtaaggtgg gctatggttc aactgttatc cctaaccgtg
    38461 gagcttggtt ggaacttgaa agcgactcaa aagatatcac ctacactcgt atcgaccgta
    38521 ctcgtaagat tccatttaca accttggttc gtgctcttgg tttctcaggt gatgatgaaa
    38581 tctttgatat ctttggtgac agcgaattgg ttcgcaacac tgttgaaaaa gatatccaca
    38641 agaatccaat ggactctcgt acagacgaag ccttgaaaga aatttacgaa cgccttcgtc
    38701 caggtgagcc taagacggct gaaagctcac gtagcttgct tgtagctcgc ttctttgacc
    38761 cacgtcgtta tgacttggca gcagttggtc gttacaaaat caataaaaaa ctcaatgtta
    38821 aaacacgttt gctcaaccaa accattgcag agccattggt agaccctgaa actggagaaa
    38881 tcttggtaga agctggtacg attatgactc gtagcgtgat tgaaagcatt gaaagccatt
    38941 tggatggcga cttgaacaag attgtctaca tcccaaacga tgcagccgtt gtgactgagc
    39001 ctgttgttct tcaaaaattc aaggttattg ctccaactga tccagatcgc gtcgtaacga
    39061 tcattggtaa tgctaaccca gatgacaagg ttcgtacggt gactcctgca gatatccttg
    39121 ctgagatgag ctacttcctc aacttggctg aaggacttgg ccgtgtagat gatatcgacc
    39181 accttggaaa tcgtcgtatc cgtgcggttg gtgaattgct tgccaaccaa gtacgtttgg
    39241 gactttctcg tatggaacgt aatgtccgtg aacgtatgtc tgttcaggac aatgaagtct
    39301 tgacaccaca acaaattatc aatattcgtc ctgtaacagc tgcagttaaa gaattctttg
    39361 gttcatcaca gttgtcacag ttcatggacc aacacaaccc gctttctgag ttgtctcaca
    39421 aacgccgttt gtcagcctta ggacctggtg gtttgactcg tgaccgtgcc ggatatgaag
    39481 tgcgtgacgt gcactacact cactatggtc gtatgtgtcc aatcgagaca cctgaaggac
    39541 ctaacatcgg tttgatcaat aacttgtcat cttacggaca cttgaacaaa tatggttttg
    39601 ttcaaacacc ataccgtaag gttgaccgtg aaacaggtgt tgtcacgaac gaaattgttt
    39661 ggttgacagc tgatgaagaa gatgaatata ctgtagctca ggctaactct cgtctgaatg
    39721 aagatggaac ctttgctgag aagattgtca tgggacgtca ccaaggggtc aaccaagagt
    39781 atccagctaa tattgttgac tacatggacg tttcaccaaa acaggtagtt gccgttgcga
    39841 cagcatgtat tcctttcttg gaaaacgatg actccaaccg tgccctcatg ggagccaata
    39901 tgcaacgtca ggctgtgcca ttgattaatc ctcaggcacc ttacgttggt actggtatgg
    39961 aataccaagc agcccacgat tctggtgcgg ctgtgattgc tcagtatgat ggtaaagtta
    40021 cttacgcaga tgctgacaag gtagaagttc gtcgtgaaga tggttcattg gatgtttacc
    40081 acatccaaaa attccgtcgt tcaaactcag gtactgctta caaccaacgc actctcgtaa
    40141 aagttggtga tgtcgttgaa aaaggcgatt tcatcgctga cggaccttct atggaaaatg
    40201 gagaaatggc gcttggacaa aacccaatcg ttgcctacat gacttgggaa ggctacaact
    40261 tcgaggatgc cgttatcatg agcgaacgct tggtgaagga cgatgtctac acatctgttc
    40321 accttgaaga atacgaatca gaaacgcgcg atacaaagct tgggcctgaa gaaatcactc
    40381 gcgaaattcc aaacgttggt gaagatgccc tcaaagacct tgacgaaatg gggattatcc
    40441 gtattggtgc tgaggttaaa gaaggtgata ttcttgtagg gaaagtaaca cctaagggtg
    40501 agaaagatct ttcagctgaa gaacgtctct tgcacgctat ctttggagac aagtctcgtg
    40561 aagtgcgtga tacttctctt cgtgtaccac acggtgccga tggtgtcgtt cgtgatgtta
    40621 agatctttac acgtgtaaat ggagatgagt tgcaatcagg tgttaacatg ttggttcgtg
    40681 tttacatcgc tcaaaaacgt aagattaagg tcggagataa aatggccgga cgtcacggaa
    40741 acaaaggggt tgtctctcgt atcgttcctg tagaagacat gccttacctt ccagacggaa
    40801 ctccagtcga catcatgttg aacccacttg gggtgccatc acgtatgaat atcggtcagg
    40861 ttatggagct tcaccttggt atggcagctc gtactcttgg tattcacatt gcgacaccag
    40921 tctttgatgg agcaagttct gaagatcttt ggtcaactgt taaagaagca ggtatggata
    40981 gcgatgccaa aacgatcctt tacgatggac gtactggtga accatttgat aaccgtgttt
    41041 ctgttggagt catgtacatg atcaaactcc accacatggt tgacgataaa ttgcacgcgc
    41101 gttcagtcgg accttactca actgttaccc aacaaccact cggaggtaaa gctcagtttg
    41161 gtggacaacg tttcggtgag atggaggttt gggctcttga agcctacggt gcgtcaaatg
    41221 tccttcaaga aatcttgact tacaagtctg acgatatcaa cggacgtttg aaagcctatg
    41281 aagctattac aaaaggcaaa ccaattccaa aaccaggtgt tccagaatcc ttccgagttc
    41341 ttgttaaaga attgcaatct cttggtcttg acatgcgtgt cctagacgaa gatgaccaag
    41401 aagtggaact tcgcgacttg gatgaaggaa tggacgaaga tgtcatccac gtagatgacc
    41461 ttgaaaaagc ccgcgaaaaa gcagcccaag aggctaaagc agcctttgaa gctgaagaag
    41521 ctgagaaagc aacaaaagcg gaagcaacag aagaagctgc tgaacaagaa taagcagttc
    41581 acttagaata gaaagggaag aaatagtggt tgatgtaaat cgttttaaaa gtatgcaaat
    41641 caccctagct tctccaagta aagtccgttc atggtcttat ggagaagtca aaaaacctga
    41701 aacaatcaat tatcgtacct tgaaaccaga acgtgaagga ctctttgatg aagtgatctt
    41761 tggtcctaca aaagactggg aatgtgcttg tggtaagtac aaacgcattc gttacagagg
    41821 aattgtttgt gaccgctgtg gggttgaagt aacgcgtacg aaagttcgtc gtgagcgtat
    41881 gggacatatc gaattgaaag ctcctgtatc tcacatctgg tacttcaagg ggattccaag
    41941 ccgtatgggc ttgacccttg atatgagccc tcgtgccctc gaggaagtta tctactttgc
    42001 ggcttatgtg gtgattgatc ctaaggatac accacttgag cacaagtcta tcatgacaga
    42061 gcgcgaatac cgagagcgct tgcgcgaata tggttatggt tcatttgttg ccaagatggg
    42121 tgcggaagcc atccaagacc ttttgaagca agtagatctt gaaaaagaaa ttgctgaact
    42181 caaagaagaa ttgaaaacag ctactggaca aaaacgtgtc aaagccatcc gtcgtttgga
    42241 tgttttggat gccttttaca agtctggaaa caaacctgaa tggatgattc ttaacatcct
    42301 tccggttatc ccaccagatc ttcgtccaat gttgcagttg gatggtggcc gttttgcctc
    42361 atctgacttg aatgaccttt accgccgtgt tatcaatcgt aacaaccgtt tggctcgttt
    42421 gcttgagtta aatgcaccag gtatcatcgt tcaaaatgag aaacgtatgc ttcaagaagc
    42481 agttgacgct ttgattgaca atggtcgtcg tggtcgtcca atcacaggac caggtagccg
    42541 tccattgaaa tcattgagcc acatgcttaa aggtaaacaa ggacgtttcc gtcaaaactt
    42601 gctcggtaaa cgtgttgact tctcaggacg ttcagttatc gccgttggtc caactcttaa
    42661 gatgtaccaa tgtggtgtgc cacgtgaaat ggcgattgaa ctctttaaac catttgtcat
    42721 gcgtgaaatc gttgcccgtg atatcgtgca aaacgtcaaa gcagctaaac gcttggtgga
    42781 acgcggagat gagcgtatct gggatatcct tgaagaagtg attaaagaac acccagtgct
    42841 tttgaaccgc gcaccgaccc ttcaccgttt gggtatccaa gccttcgagc cagtcttgat
    42901 tgatggtaag gctcttcgct tgcacccact tgtctgtgaa gcctacaatg ctgactttga
    42961 cggggaccaa atggccatcc acgtaccact ttcagaagaa gcacaagcag aagctcgtat
    43021 cctcatgcta gctgctgagc acatcttgaa cccgaaagat gggaaaccgg tagttactcc
    43081 atctcaggac atggttttgg gtaactacta cttgaccatg gaagaagctg gtcgcgaagg
    43141 tgaaggaatg gtcttcaaag accgtgacga agcggttatg gcttaccgca atggttatgt
    43201 tcacctccac tcacgtgttg gtatcgcaac agacagcctc aacaagcctt ggacagaaga
    43261 gcaaagacat aaggtcttgc ttacaacagt tggtaaaatt ctcttcaacg atatcatgcc
    43321 agaggggcta ccatacttgc aagaaccaaa caatgccaac ttgacagaag gtgttccagc
    43381 taaatacttc ttgccacttg gtggagatat caaggaagct atcagcaatc ttgagctcaa
    43441 ccctccattc aagaagaaaa acctcggaaa tatcatcact gaaatcttca aacgtttccg
    43501 tacgacagaa acttctgccc tacttgaccg catgaagaac ctcggttacc accactcaac
    43561 tcttgcagga ttgacagtgg gtattgccga tatcccagtc gttgatgaca aggctgaaat
    43621 cattgaagaa tcacacaaac gtgtcgaaca aatcaccaaa caattccgtc gtggtatgat
    43681 cacagacgac gagcgttaca atgctgttac agctgaatgg cgtgctgccc gtgaaaaact
    43741 tgagaaacgc ttgattgcta atcaagatcc taagaaccca atcgttatga tgatggactc
    43801 tggagcccgt ggtaacatct caaacttctc acagcttgcc ggtatgcgtg gtctgatggc
    43861 tgctccgaat ggacgtatca tggaattgcc aatcctttca aacttccgcg aaggtttgtc
    43921 ggtattggaa atgttcttct caactcacgg tgctcgtaaa ggtatgaccg atacggccct
    43981 taagacagcc gactcaggtt acttgactcg tcgtttggtc gacgttgccc aagacgttat
    44041 catccgtgag gacgactgtg gaactgaccg tggtctcttg atccgttcta tcgcagaagg
    44101 aaaagagatg atcgagtctc tcgaagagcg tctcaacggt cgttacacta agaaaactgt
    44161 taaacatcca gaaactggtg cagtgattat tggtccaaat gaattgatta cagaagacaa
    44221 ggcgcgtgaa attgtcaatg ctggtgtgga agaagtgact atccgttctg tatttacatg
    44281 taacactcgt cacggtgtct gccgtcactg ttacggtatc aacttggcga ctggtgatgc
    44341 ggttgaagtt ggtgaagcag ttggtacaat cgctgcccaa tctatcgggg aacctggtac
    44401 acagcttaca atgcgtacct tccacacagg tggggttgcc tcaaataccg atatcactca
    44461 gggtcttcct cgtgtccaag aaatctttga agcccgcaat cctaaagggg aagcggttat
    44521 cacagaggtt aaaggacaag ttactgctat cgaagaggat gcatcaactc gtaccaagaa
    44581 agtctttgtt aagggtgaaa ctggcgaagg tgaatatgtc gttccattta cagctcgtat
    44641 gcgtgtcgaa gttgggggcc aagtagcgcg tggtgctgct ctgacagaag gttctatcca
    44701 accaaaacgt ctccttgcag ttcgtgatgt cttgtcagtt gaaacgtacc ttctcggtga
    44761 agtacaaaaa gtttaccgta gccaaggggt agaaatcggt gacaaacaca tcgaggtaat
    44821 ggttcgtcaa atgatccgta aagtccgtgt catggatcca ggtgatacag atcttctcat
    44881 gggtaccctc atggatatca atgactttac agatgccaac aaagatgtcc ttatcgcagg
    44941 tggagttcca gcgacaggtc gcccagtcct tatgggaatt accaaagcct cacttgaaac
    45001 aaacagtttc ttgtcagcgg cttccttcca ggaaacaact cgtgtcctta ctgacgcagc
    45061 tatccgtggt aagaaagacc atctccttgg acttaaagaa aatgttatca tcggtaagat
    45121 catcccagct ggtactggta tggcccgtta ccgtaacctt gaaccacatg ctgtcaacga
    45181 agaagaatac cttaatcctc cagtagagga agaaggaaat gaagaaacaa cagaagtagt
    45241 tgtggatact gccgttgaaa ctgtggaaga aacagtagaa taagagagaa tgagagaacc
    45301 ctcgggttct ctcattctct cttctgaaaa ctttctccat ttttccacga aatgtggtaa
    45361 aataaaagaa agaagctgac aaaggagacg ggtatggaac aaacattctt tatcatcaaa
    45421 ccagatggtg taaaaagagg gctagtgggt gaagtgttaa agcgcatcga acaacgtgga
    45481 tttacaatcg aaaaattgga gtttcgttca caggtttcag aagagttgat tgaccagcac
    45541 tatcaggact tggttggtca gagtttttac ccaccgattc gtgaattcat gacttcaggt
    45601 ccagttcttg tgggtgtcat ttctggtccc aaagtaatcg aaacttggcg gaccatgatg
    45661 ggtgcaactc gtccagaaga agctttacca ggcactattc gaggtgattt tgcaaaagct
    45721 gctggagaaa atgagattat ccaaaatgtt gtacatggtt cagattcaga agagtcagct
    45781 aagcgagaaa ttgctctttg gttttaagag tggattggct caatcaattg gttaaaagct
    45841 catttgaata gaaagtatag tcaattagtt taagacatga cgcatgatat caaacttttt
    45901 agtttttgat atggtgcgtt ttttgattaa gtgactatta gtttgtctcg ctccgttagg
    45961 tgcgagacaa aaaaaacacc cgctatgcgg gtgcgcgtcg aaggttatac caaaaaaact
    46021 ccaaacgcga tacaataaag gtgttcaatc caattgtaaa gcgaaaggag aaaaatatgg
    46081 cacaaaaggt tcttttatcc tgttcttgtt tcaattgact atatttctat actttttctt
    46141 cctttctctg tgaaaatcgc aagtttttcc caccttttct caatactgaa acaacatctt
    46201 tccagaactt caataatttc tttttgtgtt aaatcattat ttaactaaat ctttggaggc
    46261 aatacgtttt caaagctact tttttaccat aggttttgag ccttcaacac agattactaa
    46321 gccaaaaatg ctctaaattt ttgaaattct aacaaattcc actcaacttt atcatcatct
    46381 ttgactttca caatatcttc ctcaaaataa catggaataa agatagtttt cttttaaaac
    46441 ggttgtagga ggaaaatctc tcctacacta ttattgattc tgagagaaaa ttgcaaaata
    46501 tcatctacca aactttcaat tattaagatt ttttgcagtt tatctgaatt agaatcgcaa
    46561 ggcttctcaa taatataatt gtcgaatttt ttcattctaa cttcctctcc attatttctt
    46621 cctttatcaa gaaaaagtta cctcaatatt aataaagtac aattctaaat taactccaat
    46681 tcttgattca tgataatatt tcagtaactc atcgtgcaat taaaaacaag gatttttatt
    46741 tcagatgatc catcgtgaac acttcatcag ccatctccca aattgccgga ttatgtgttg
    46801 cgataatgat tagcctatta tcatctcgaa gagatagcaa aatctccata atcaactgag
    46861 aggttgctgg gtctattgaa gctgttggct catctgccag aataaagggt ggattcttta
    46921 agataatttt tgccaaggca acccgttgcg attctccgcc cgataactca aagatgcgct
    46981 tatctaggtc aagataagcc aggccgacct gttctaaagc ctgcttctgc ctcaaccgct
    47041 gttccgaccg actcaacttt tgaccaatga gacctagctt aaggttttct tcaatacttt
    47101 ggttttcaat taagccaaag ttctggaaga ggtagcccaa ttcgtgacgg aaaaaatcac
    47161 tcgatttata attggccaag tctttacctc ggtaaaaaat cgtcccatca taaggttcta
    47221 atttcccaat catgttcatc aaggttgttt ttccgctacc acttgaacca attaaggcat
    47281 agacttttcc agcctcaaat gtcattgaaa gattcgaaaa taactctcgt tctccaaaag
    47341 atttactcac ctgtttaagt tcaatcatat taacctccct tcaaaacaag aatggacatc
    47401 ttgttttctt tctgcatttg gacatgtaac tgtaaaagag atagaccagt aaagagtaac
    47461 aagactaaga aagcaactcc tatctctacc tgaagaaata cactcgcaac aaatcccagt
    47521 aaaaacacac ccagttgagc aaagagataa gtgcgatgga tttctaagaa cctgagacct
    47581 gcaatgcgtt tgataaaaat ggcacgtcta aattcttcaa agtagagcct attcatagtg
    47641 ttaaacaaca agattgaagt tgcaatccca agcacagctc ctgctagcat tacccaacgt
    47701 tccctctgga tattatccaa taatgtgatg tagttgtggt aacctgtttg catttctgag
    47761 acccaatttt caatgccttg tctctggata agctcctggg catcagacaa ttgattaaag
    47821 agaacgtagt tctgtactgc gtctatccaa aacaaaatgg actgtggacc agttgattgg
    47881 ggtgttataa caatgatgat tggatctttc aaaaactgct ggtaagaaat aggggtcgta
    47941 ttatacacaa aacgatcctg acctgattct aaataaccta ccgtagcagt catttgctgt
    48001 cgttcatctt gactagacat gcgactggtt aagtcgtctt caaaaacaga tttataatgt
    48061 tcttcctctg aacggaggtg ttcaggcagc aataagacaa actcccctac attaaggtga
    48121 ttcatctttt gctcaatagt tgtatctaca ggaatgtttt gacgctccaa gtattgcggt
    48181 gtgacgataa ggacattgcc attcgggttg taatcgtgcc attctgtaga ggttatcaag
    48241 tttttggagg aagccatgcc attttgcaaa gtacggtcaa ttaactggtg tctagataag
    48301 aaagcctttt gttctgaaac agccagatcc atcaattgat accaagttct gagtttcctt
    48361 tgagcttgtt catcaaaacc aggactcgtt ccttcacggc tgattgatag ggtaatcagt
    48421 tgcctttcct gactccaagc ctcttgtcca atccgatgct gttgccaggc ttgggaatac
    48481 tttaagctac tccctattcc cagcgttaca ataataatcg ctaatagttg accgattaaa
    48541 atcaaactaa tgattcctct gacaggcact tgccctttta taatctgcat caggtgtatc
    48601 ttttttatcc caactgcgaa gagttgagcg aaaaacaggg agatcgacaa caagatgaga
    48661 ttataactga gcaagcctgc tcctatggtc attagggatt gcgttggaag cgacagaatt
    48721 ttttgcataa gaatggcgag cacgccagct aaactgaaac caacagctat ccctttcaaa
    48781 tcctcaccaa ctggtctaag gaaaatggac caccgtttct ctcctgaaat gaggcgaatg
    48841 cccgacgacc gtaattggct aatttgacta attaaagtca gtgctacaaa ggttaagatg
    48901 aaaatcaata gactgattaa ctgaaatccg ttactaaaga tagccattaa cgtagatagt
    48961 ttagatggaa ttgtcaggtt catgttagtc aagccaagtt gacttagctc ctcccttagc
    49021 aagtgaatat ctaggtgtcc atcgaataca aaatagtttg tttcaacact actactttga
    49081 gcatcttcta gttttttttc ctgaagccca tcaggcaact ttccgtcccc aaaggtcgta
    49141 taagaaaaaa ctgtagtacc ttctgagtta gaatcttggt gttgaatcgc aataaagcta
    49201 tctgtttctt ctgctagttt ttccaagcgt gtagcaacat gctgaaaagt tgtttcaggg
    49261 gaagaatcac gtacaacaac gttggggtaa taatgggaga catatgtatc agtccaaatg
    49321 gtaaataccc aaacaaagaa caaactagca agcaggttgg atatgagtat aaataatttt
    49381 ttcatagtgc attccttatt ctaaaacaga gggcagaaat acccctgccc tctataaact
    49441 aacaagctta ctaaactatt gataaaagaa tcttcttcaa ttattcttta ccatcccgca
    49501 tcaaatctaa attttaacat attattactc ctctgaatga aatattatga aaatgagcga
    49561 aatgcaacta catattttaa ttagaaatct cagtctgaat tatagtatcc tattttttcc
    49621 tcctttctaa ctgcacgttc ctttctacag gcagagacct aattttataa accaatctta
    49681 aatactttag attttgtaac tcataatttt caacagttgg ttagctatga aagcatttta
    49741 tcaaacatct ccattcttat atctatctgg tattgttaca agctctcatc agaatacctt
    49801 tctctaaata gttgaatttt aaagtaatac gaaatcaatc agccttccca acatcaagac
    49861 cattggactt cttttgtgat tgcactcgaa tctccaattg tctattcttc tgaataaact
    49921 gttggtaagg aattgtgtta ctaaacataa aaacacctag taatactaat atagctaatt
    49981 tttgaattcc acgatttttc ttcattcgtg aaaccctttt ctttttcctt gtttttattt
    50041 taatatatat atattattcg gtcaagc
//
LOCUS       DAVMJI010000013        47241 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.013, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000013 DAVMJI010000000
VERSION     DAVMJI010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47241
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.013"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..309
                     /locus_tag="VYR58_000896"
     CDS             <1..309
                     /locus_tag="VYR58_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV3622087.1"
                     /translation="ENTILHSDQGWQYQHDSYHRFLESKGIQASISRKGNSPDNSMME
                     SFFGILKSEMFYGYEKSFQSLKQLEQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
                     "
     gene            complement(352..993)
                     /gene="plsY"
                     /locus_tag="VYR58_000897"
     CDS             complement(352..993)
                     /gene="plsY"
                     /locus_tag="VYR58_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV3622088.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1129..3072
                     /gene="parE"
                     /locus_tag="VYR58_000898"
     CDS             1129..3072
                     /gene="parE"
                     /locus_tag="VYR58_000898"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV3622089.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLATVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3492..5963
                     /gene="parC"
                     /locus_tag="VYR58_000899"
     CDS             3492..5963
                     /gene="parC"
                     /locus_tag="VYR58_000899"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV3622090.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQIGIVPILSSYIAHRREVILARSRFDKEKSEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6095..7117
                     /locus_tag="VYR58_000900"
     CDS             6095..7117
                     /locus_tag="VYR58_000900"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV3622091.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7173..7877
                     /locus_tag="VYR58_000901"
     CDS             7173..7877
                     /locus_tag="VYR58_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV3622092.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            7942..8631
                     /locus_tag="VYR58_000902"
     CDS             7942..8631
                     /locus_tag="VYR58_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV3622093.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8628..9551
                     /locus_tag="VYR58_000903"
     CDS             8628..9551
                     /locus_tag="VYR58_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV3622094.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9566..10210
                     /gene="pcp"
                     /locus_tag="VYR58_000904"
     CDS             9566..10210
                     /gene="pcp"
                     /locus_tag="VYR58_000904"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV3622095.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10378..10608
                     /locus_tag="VYR58_000905"
     CDS             10378..10608
                     /locus_tag="VYR58_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV3622096.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10658..10738
                     /locus_tag="VYR58_000906"
     tRNA            10658..10738
                     /locus_tag="VYR58_000906"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10692..10694,aa:Tyr,seq:gta)
     gene            10748..10819
                     /locus_tag="VYR58_000907"
     tRNA            10748..10819
                     /locus_tag="VYR58_000907"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10780..10782,aa:Gln,seq:ttg)
     gene            10981..12183
                     /gene="rpsA"
                     /locus_tag="VYR58_000908"
     CDS             10981..12183
                     /gene="rpsA"
                     /locus_tag="VYR58_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV3622097.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(12268..13594)
                     /locus_tag="VYR58_000909"
                     /pseudo
     CDS             complement(12268..13594)
                     /locus_tag="VYR58_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            13788..14285
                     /locus_tag="VYR58_000910"
     CDS             13788..14285
                     /locus_tag="VYR58_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV3622098.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            14285..15940
                     /gene="dnaX"
                     /locus_tag="VYR58_000911"
     CDS             14285..15940
                     /gene="dnaX"
                     /locus_tag="VYR58_000911"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV3622099.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            15968..16162
                     /locus_tag="VYR58_000912"
     CDS             15968..16162
                     /locus_tag="VYR58_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV3622100.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            16312..17082
                     /gene="sufC"
                     /locus_tag="VYR58_000913"
     CDS             16312..17082
                     /gene="sufC"
                     /locus_tag="VYR58_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV3622101.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            17110..18372
                     /gene="sufD"
                     /locus_tag="VYR58_000914"
     CDS             17110..18372
                     /gene="sufD"
                     /locus_tag="VYR58_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV3622102.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGDDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            18383..19609
                     /locus_tag="VYR58_000915"
     CDS             18383..19609
                     /locus_tag="VYR58_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV3622103.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            19596..20036
                     /locus_tag="VYR58_000916"
     CDS             19596..20036
                     /locus_tag="VYR58_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV3622104.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            20090..21502
                     /gene="sufB"
                     /locus_tag="VYR58_000917"
     CDS             20090..21502
                     /gene="sufB"
                     /locus_tag="VYR58_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV3622105.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(21733..22974)
                     /locus_tag="VYR58_000918"
     CDS             complement(21733..22974)
                     /locus_tag="VYR58_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV3622106.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKNLIGQGYITTERPSFEMIADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            23077..24186
                     /locus_tag="VYR58_000919"
     CDS             23077..24186
                     /locus_tag="VYR58_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV3622107.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            24832..25179
                     /gene="ssrA"
                     /locus_tag="VYR58_000920"
     tmRNA           24832..25179
                     /gene="ssrA"
                     /locus_tag="VYR58_000920"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(25362..25449)
                     /locus_tag="VYR58_000921"
     tRNA            complement(25362..25449)
                     /locus_tag="VYR58_000921"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(25413..25415),aa:Ser,seq:gga)
     gene            25611..26351
                     /locus_tag="VYR58_000922"
     CDS             25611..26351
                     /locus_tag="VYR58_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV3622108.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            26348..27259
                     /gene="pfkB"
                     /locus_tag="VYR58_000923"
     CDS             26348..27259
                     /gene="pfkB"
                     /locus_tag="VYR58_000923"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV3622109.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            27256..29208
                     /locus_tag="VYR58_000924"
     CDS             27256..29208
                     /locus_tag="VYR58_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV3622110.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            29372..31597
                     /locus_tag="VYR58_000925"
     CDS             29372..31597
                     /locus_tag="VYR58_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV3622111.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(31642..32076)
                     /locus_tag="VYR58_000926"
     CDS             complement(31642..32076)
                     /locus_tag="VYR58_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622112.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            32214..33356
                     /locus_tag="VYR58_000927"
     CDS             32214..33356
                     /locus_tag="VYR58_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV3622113.1"
                     /translation="MIYFDNSATTKPYPEALETYVQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPADT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            33365..34579
                     /gene="thiI"
                     /locus_tag="VYR58_000928"
     CDS             33365..34579
                     /gene="thiI"
                     /locus_tag="VYR58_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV3622114.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            34714..35538
                     /locus_tag="VYR58_000929"
     CDS             34714..35538
                     /locus_tag="VYR58_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV3622115.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            35560..36299
                     /locus_tag="VYR58_000930"
                     /pseudo
     CDS             35560..36299
                     /locus_tag="VYR58_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            36312..37478
                     /locus_tag="VYR58_000931"
     CDS             36312..37478
                     /locus_tag="VYR58_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV3622116.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYLFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYIAIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            37986..39479
                     /locus_tag="VYR58_000932"
     CDS             37986..39479
                     /locus_tag="VYR58_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV3622117.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            39492..40034
                     /locus_tag="VYR58_000933"
     CDS             39492..40034
                     /locus_tag="VYR58_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV3622118.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRYSEEVVA"
     gene            40031..40951
                     /locus_tag="VYR58_000934"
     CDS             40031..40951
                     /locus_tag="VYR58_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV3622119.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGREIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNT
                     KNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLR
                     INSGMVILRPKTPNLNHNWQSKNLWKNLKL"
     gene            41043..41279
                     /locus_tag="VYR58_000935"
     CDS             41043..41279
                     /locus_tag="VYR58_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV3622120.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            41276..41689
                     /locus_tag="VYR58_000936"
     CDS             41276..41689
                     /locus_tag="VYR58_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV3622121.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            41807..42772
                     /locus_tag="VYR58_000937"
     CDS             41807..42772
                     /locus_tag="VYR58_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV3622122.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            42757..43281
                     /locus_tag="VYR58_000938"
                     /pseudo
     CDS             42757..43281
                     /locus_tag="VYR58_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            43253..43480
                     /locus_tag="VYR58_000939"
                     /pseudo
     CDS             43253..43480
                     /locus_tag="VYR58_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            43510..46860
                     /locus_tag="VYR58_000940"
     CDS             43510..46860
                     /locus_tag="VYR58_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV3622123.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRDIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRARMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
BASE COUNT        14551 a         8318 c        10337 g        14035 t
ORIGIN      
        1 gagaatacga ttctccatag tgaccaaggc tggcaatacc aacacgattc ttatcatcgg
       61 ttcctagaga gtaagggaat tcaagcatcc atatcacgca agggaaacag cccagacaat
      121 agtatgatgg agtccttctt tgggattctg aaatcggaaa tgttttacgg ttatgagaag
      181 tcgtttcagt cgcttaagca attggaacaa gccattatag actatattga ttattacaac
      241 aataagagaa ttaaggtaaa actaaaagga cttagccctg tgcaatacag aactaaatcc
      301 ttcggataaa ttaattgtct aactgtttgg gggcagtaca gaactggcgt tttatttttt
      361 aggatcttga tgggttaggt tcaatcccca agggaccaaa ttttcagttt tatttttgat
      421 acgagctata ttgtccttat gacgaatgat aatcaaacta gcaagtgcta agataatagc
      481 gatgaagaga gagtcatagt tactcaggat aaaaccaaaa agtggaaaga gcagaacccc
      541 gataacagcc gcgatcgatg ctgtgacact agacagtgaa atcatactgc caagatagag
      601 agctccaaag aagataatcg caaggtagag acagaagata ggcgcaaatc cgaaaattac
      661 tccagcactg gttgcgacag ccttaccacc tttaaatcct gcaaagatag ggaaggtatg
      721 gccgataaca gccaaaagtc caaagatgag aggagaaacg ccttgtagat gaaaaataat
      781 cggaagcagc gttgctaggg ttcctttgaa aaagtcaatc acaaaggttg ccataccagc
      841 tttcttacct aaaatgcgga aggtattggt cgttccagtg ttaccagaac catgctcgcg
      901 tagattgatt tgaaagaata cttgtccaat ccagagacca gatggaatcg aacccagcag
      961 ataggctagg attaataaaa ctattgtaat catactccta ttatatcatg aattgggaaa
     1021 gaaaagcaga gaatctctgc taaaattgtc acatcggaga aagaaaaatt ttgcaaaatc
     1081 cttggaaaac ctgtagaata gtaaagatga acgaatagga ggttccttgt gtcaaaaaag
     1141 gaaatcaata ttaacaatta taatgatgat gctattcagg tgctagaagg gttggatgcg
     1201 gtccgaaaac gtccagggat gtatattgga tcgaccgatg gcgctggtct tcatcaccta
     1261 gtttgggaaa tcgttgataa tgcagtcgat gaagccttgt ctgggtttgg tgatcgtatt
     1321 gatgtaacta tcaataaaga cggtagtcta acggttcaag accatggacg tgggatgccg
     1381 acaggtatgc acgctatggg aattccaact gttgaggtta tctttaccat tcttcatgcc
     1441 ggagggaaat tcggtcaagg tggctataag acatcaggtg gacttcacgg agtgggttct
     1501 tccgttgtta acgccctttc tagctggtta gaagttgaaa ttacccgtga tggcgcagtt
     1561 tacaagcaac gttttgaaaa tggtggaaaa cctgtcacga ctttgaagaa aatcggtaca
     1621 gcacccaagt ctaaaacagg caccaaagtt acttttatgc ctgacgcgac tatcttttct
     1681 acgacagatt tcaagtacaa taccatttca gagcgcctta atgaatcagc ctttctcttg
     1741 aaaaatgtga ccttgtcttt aacggacaag cgaacagatg aagcgattga gttccactat
     1801 gagaatggag tacaagattt tgtttcttat ctcaacgaag ataaggaaat cttgacgcca
     1861 gttctttact ttgaagggga agacaatggt tttcaagtgg aagtagccct ccagtacaat
     1921 gacggattct cagataacat tctatccttt gtcaataacg ttcgcaccaa ggacggtgga
     1981 acgcacgaga caggactcaa gtctgccatt accaaggtca tgaatgacta tgcacgtaaa
     2041 acaggtcttc tcaaggaaaa agataaaaac cttgaaggtt cagactatcg tgagggacta
     2101 gcgaccgttc tttctatctt agttcctgaa gaacacttgc agtttgaagg acagaccaag
     2161 gataaactag gaagccccct agctcgccca gttgtggatg gaatagtggc tgataagttg
     2221 acctttttcc ttatggaaaa tggggaatta gcttctaacc tcatccgcaa ggctatcaag
     2281 gcccgtgatg ctcgtgaagc agcacgtaag gcgcgtgatg agagccgaaa tgggaagaaa
     2341 aacaagaaag ataagggctt gttgtctggg aaattgaccc cagcccaatc taagaatcct
     2401 gctaagaatg aactctatct agttgagggg gactctgccg gtggttctgc caaacaaggt
     2461 cgtgaccgca agttccaggc tattctacct cttcgtggta aggttgtcaa tacagccaag
     2521 gccaagatgg cggatatcct caaaaatgaa gagatcaata ccatgattta taccattggt
     2581 gcgggtgttg gagcagactt ctctattgaa gatgccaact atgataagat cattatcatg
     2641 accgatgcgg ataccgacgg tgcccatatc cagaccttgc tcttgacatt tttctaccgt
     2701 tacatgcgtc cgctagtcga ggcaggtcat gtctatattg ccctcccacc tctttacaag
     2761 atgtccaaag gtaaaggcaa gaaagaagaa gtggcctacg cttggacgga tggagaacta
     2821 gaagaactcc gtaaacagtt cggtaaaggc gctaccctcc aacgatacaa aggacttggt
     2881 gagatgaatg cggaccagct ctgggaaaca accatgaacc cagaaacacg taccctcatc
     2941 cgtgtcacaa ttgaagattt agcgcgcgcc gaacgccgcg tcaatgttct catgggagat
     3001 aaggtagaac cacgccgtaa atggattgaa gataatgtca agtttacgct agaagaagcg
     3061 acagtgtttt aatgaaagaa aataatatgt tagtaaactg gaaattagag tcggatgtga
     3121 atgactatgt gaaaaagcag tttgaaaatc ttggtttgaa aaaattgcag gattattaat
     3181 gaagaatctg ctatgagtgc ttatcttaaa gaggcgctta agggagcggt taagacacaa
     3241 actaagacta attttggaaa accagatttt catattgaaa aatacaaaca ggatagtttg
     3301 gttacttatc gtaactgaac acgggaggaa ttcccgtaaa atatctttta ctgcataaaa
     3361 acctactcta cattctttga aaggagttga acacgcccta gatactgtgt gaaaaagata
     3421 aattctcttg tgagtttgct tacttcaaga attttctatt ttcacttggt attttatggg
     3481 ctttgtatct tatgtctaac attcaaaaca tgtccctgga ggacatcatg ggagagcgct
     3541 ttggtcgcta ctccaagtac attattcaag accgggcttt gccagatatt cgtgatgggt
     3601 tgaagccggt tcaacgccgt attctttatt ctatgaataa ggatagcaat acttttgaca
     3661 agagctaccg taagtcggcc aagtcagtcg ggaacatcat ggggaatttc cacccacacg
     3721 gggattcttc tatctatgat gccatggttc gtatgtcaca gaactggaaa aatcgtgaga
     3781 ttctagttga aatgcacggt aataacggtt ctatggacgg agatcctcct gcggctatgc
     3841 gttatactga ggcacgtttg tctgaaattg caggctacct tcttcaggat atcgagaaaa
     3901 agacagttcc ttttgcatgg aactttgacg atacggagaa agaaccaacg gtcttgccag
     3961 cagcctttcc aaacctcttg gtcaatggtt cgactgggat ttcggctggt tatgccacag
     4021 acattcctcc ccataattta gctgaggtca tagatgctgc agtttacatg attgaccacc
     4081 caactgcaaa gattgataaa ctcatggaat tcttgcctgg accagacttc cctacagggg
     4141 ctattattca gggtcgtgat gaaatcaaga aagcttatga gactgggaaa gggcgcgtgg
     4201 ttgttcgttc caagactgaa attgaaaagc taaaaggtgg taaggaacaa atcgttatta
     4261 ctgagattcc ttatgaaatc aataaggcca atctagtcaa gaaaatcgat gatgttcgtg
     4321 ttaataacaa ggtagctggg attgctgagg ttcgtgatga gtctgaccgt gatggtcttc
     4381 gtatcgctat cgaacttaag aaagacgcta atactgagct tgttctcaac tacttattta
     4441 agtacaccga cctacaaatc aactacaact ttaatatggt ggcgattgac aatttcacac
     4501 ctcgtcagat tgggattgtt ccaatcctgt ctagctatat cgctcaccgt cgagaagtga
     4561 ttttggcgcg ttcacgcttt gacaaagaaa agtctgagaa acgtctccat atcgtcgaag
     4621 gtttgattcg tgtgatttcg attttggatg aagtcattgc tcttatccgt gcttctgaga
     4681 ataaggcgga cgccaaggaa aacctcaaag ttagctatga ttttacggaa gaacaggctg
     4741 aggctatcgt aactttgcaa ctgtaccgtt tgaccaatac cgatgtggtt gtcttgcagg
     4801 aagaagaagc agagcttcgt gagaagattg ctatgctggc ggctattatc ggtgatgaaa
     4861 ggactatgta caatctcatg aagaaagaac ttcgtgaggt caagaagaaa tttgcaactc
     4921 ctcgtttgag ttctttagaa gacactgcga aagcaattga gattgataca gctagtctta
     4981 tcgctgagga agatacctac gtcagcgtga ccaaggcagg ttacatcaag cgtaccagtc
     5041 cacgttcctt tgcggcttcc accttggaag aaattggcaa gcgtgatgat gaccgtttga
     5101 tttttgttca atctgccaag acaacccagc acctcttgat gttcacaagt cttggaaatg
     5161 tcatctacag accaatccat gagttggcag atattcgttg gaaggacatc ggagagcatc
     5221 tgagccaaac catcacaaac tttgaaacga atgaagaaat cctttatgtg gaagtactgg
     5281 atcagtttga cgatgcgaca acctactttg cagtgactcg ccttggtcaa atcaaacggg
     5341 tagagcgaaa agaattcact ccatggcgga cctatagatc taagtctgtc aagtatgcta
     5401 agctcaaaga cgatacagat cagattgtag cagtggctcc gattaaacta gatgatgttg
     5461 tcttggttag tcaaaatggt tatgccctgc gtttcaatat cgaagaggtt ccggttgtcg
     5521 gtgctaaggc agcaggtgtc aaggctatga atttgaaaga agatgatgtc ctccaatctg
     5581 gctttatctg taatacttcg tccttctacc tcttgaccca gcgtggaagc ttgaaacgtg
     5641 tttccattga ggaaattcta gcaaccagcc gtgccaaacg aggattacaa gtcttgcgtg
     5701 agttgaaaaa caaaccgcat cgtgtcttct tggcaggagc agttgcagag caaggatttg
     5761 ttggcgattt cttcagtacg gaagtggatg tgaacgacca aactctgctt gtccaatcca
     5821 ataaaggaac aatctatgaa agccgattgc aagacttgaa cttgtcagaa cgcactagca
     5881 atggaagctt catttctgac acgatttcag atgaagaagt ttttgacgct tatcttcagg
     5941 aagtagttac tgaagataaa taagtgaaat gaagaatcag ttctaagagc tggtttttat
     6001 tggagaaatt ttctgaaaat tacaaaatat acttgctatt ttagaaaaat agtgtagaat
     6061 ataagaaata ggtttttaga ataaggagtg gaatatgaca gtaacgattg attgggaaaa
     6121 cctcggtttt tcctatatga aattacctta tcgctatctt gctcatttca aaaatggaca
     6181 atgggatcaa ggagagctta cagaggatgc aactttgcat atttcagagt cttctccaag
     6241 tcttcactat ggacaacaag catttgaagg tttgaaagct tatcgtacta aggatggcag
     6301 tgttcaactg ttccgtcctg atgaaaatgc taaacgtctg caacgtacat gtgaccgtct
     6361 cttgatgcca caagttccga cagacatgtt tgtagaagct tgtaaagcag ttgtccgtgc
     6421 gaatgaagaa tacgtaccac catacggaac aggtggaacc ttatatcttc gccctctttt
     6481 gattggtgtc ggagatatta tcggggtaaa accggcagaa gagtacattt tcaccatctt
     6541 tgctatgcca gttggaaatt actttaaagg tggtttggtc ccaaccaact tcttgattca
     6601 ggatgagtac gaccgtgcag caccaaatgg tacaggtgcg gctaaggttg gtggaaacta
     6661 tgctgcaagt ctcttaccag gaaaaatggc caagtcacgt catttctcag atgttatcta
     6721 tctggaccca tcaactcata caaagattga agaagtcgga tcagctaact tctttggaat
     6781 tacagctgat aatgaatttg taacaccatt gagtccatct atcttgccat ctattaccaa
     6841 gtattccttg ctttatttgg cagaacatcg cttgggatta actcctattg agggtgatgt
     6901 tccaattgat aatcttgacc gttttgtaga ggcaggtgcc tgtggtacag cagcggttat
     6961 ttctccaatt ggaggtattc aacatggtga tgatttccat gtattctata gtgaaacaga
     7021 agtaggtcct gtgacgcgta aattatataa tgaattgacg ggtattcagt ttggcgatat
     7081 tgaagcgcca gaaggttgga ttgtaaaagt agattaaaat aaaccaaagg agatttttta
     7141 tgaaatagaa aaagtggctc ttaacagcag gagtggtcct gagcacgtca gctattttag
     7201 tggcttgtgg aaaaactgat aaagaagcag atgcaccgac aacattttct tatgtctatg
     7261 cagtagatcc agcatcattg ggctacagta tagcgactcg aacatcgagg acagacgtta
     7321 ttggaaatgt tattgatggt ttgatggaaa atgataaata cggcaatgtt gctccttctc
     7381 aaaaagacta tgatttgaat agtacaggat gggctccaag ctatcaagat ccagcgtctt
     7441 acttgaatat tatggatcca aaatctggtt ctgccatgaa acaccttggc attacgaaag
     7501 gaaaagataa ggatgttgta gctaaacctg gtttggataa atataagaaa ttgttagaag
     7561 atgctgtttc tgagaccact gacctagaga agagatatga aaaatatgcc aaagctcaag
     7621 cttggtcgac agatagttca ttattgatgc caacagcttc atctggtggt tctccagttg
     7681 taagtaacgt agtaccattc tcaaaaccat actcacaagt tggtattaag ggggaaccat
     7741 atatctttaa aggaatgaaa ttgcaaaaag atattgttac aacaaaagaa tataacgagg
     7801 tttttaaaaa atggcaaaaa gaaaaattgg aatccaatag caaataccaa aaagaactag
     7861 aaaaatacat taaataagga atggtattga tcttgataaa atttttaaaa tactgtcatt
     7921 ttgaatataa aggagtttga tatggagtgg attagattaa taggaatagc aatcattgtt
     7981 gtgggtttta ttttaaaatt tgatacaatt gcaacagtag tcttagctgg tttggttaca
     8041 gctttagttt caggtgtttc tctcgttgaa tttttggaga ttttgggaaa agaatttagc
     8101 aatcagcgag tgctcacgat ttttatggtt accttgcctc ttgtggggct gtcagaaacc
     8161 tttggactca agcaacgatc aatcgatttg attcgaaaga ttaaaggtct gacagttgga
     8221 aacttctata cagtttattt ctttattcga gagttagctg gtttcttttc aattcgtcta
     8281 ggaggacacc ctcagtttgt cagacctttg gttcaaccta tgggagaagc agctgcagag
     8341 tctcaattag gtagaaagtt aacagaggtt gaagatgaga caataaaagc gcgtgcggct
     8401 gcgaatgaaa attttgggaa tttctttgct caaaatacgt ttgtaggtgc tgggggagtc
     8461 ctcttgatag ggggaacatt agatcagtta ggctatgaaa gcaattatgc agggattgct
     8521 tctacatcta ttattgttgc tgttataaca cttattgtag tggggattta caattattta
     8581 tttgataaaa aattgatatc aaaaaagact aggggaggag aacaaaaatg acagagttgg
     8641 caaagcaact attagagttg acctatattg tgattggttg tcaatttctc catacagcct
     8701 attgtagtta taaagataaa acaaacccag ttcgacttgg gacatctgca ttttggactc
     8761 tattgtctat tacgtttata ggtggttcct atatgccaaa tatgagtatt ggtattattg
     8821 taatcctatt atcgctgtta acattgttta agcaagtccg tatcggaacc ttgccatcct
     8881 tagatgaaat gaaagccaat attgaatcta acaggttgaa aaataaaatt tttattccag
     8941 ttatgctgat ggcaatactt gcgttggtct tagcgcaaat gattccagaa tttagcaaga
     9001 tttcgattag ccttgccgcc ttgtttgcta caatttctgt tcttgtgatt accaatagtc
     9061 accctaagag tctgttatca gaaaataatc gaatgactca gcaagtttca acaagtggta
     9121 ttgttcctca attattaggg gctttggggg ctatttttac tgtagcaggt gttggtgatg
     9181 ttatctctca tctgattagc ggtattgttc cttcagatag tcgctttata ggagttttgg
     9241 cctatgttct tggaatggtt ctattcacaa tgattatggg aaatgctttt gcagcattca
     9301 ccgttattac agcaggtgtt ggagttccct ttgtatttgc tctgggagct aatccaattg
     9361 tggctggtgc tcttgccatg acagcaggtt attgtgggac cttattgacc ccaatggctg
     9421 ctaattttaa cgctctacca gcagcattga tggatatgaa agatcagaat ggcgttataa
     9481 aggctcaagc aggtgttgct ctagtaatga ttgttattca catattctta atgtactttc
     9541 tcgcatttta gtaaaggaaa ataaaatgaa aatattggtt acaggtttta atccttttgg
     9601 aggtgaaaag attaatccag ctttggaggc tgtaaaatta ttaccatctg agattaatgg
     9661 ggctgaagtt cgctgggtag aaattccaac ggttttttat aagtcgtcag aagttttaga
     9721 ggcagaaata ttacgatatc aaccagatgc tgtactttgt attggacaag caggcggcag
     9781 gaccggctta acacctgaac gagtagctat taatcaagat gatgctcgca tacctgataa
     9841 cgaaggcaat caaccaattg atacaccgat tcgtattgat ggagcatcgg cctattttag
     9901 tagtttacct atcaaagcga tggtacaagc tatcaaaaaa cagggacttc cggcagttgt
     9961 atccaatagt gcaggaacct ttgtttgcaa tcatttgatg taccaagctc tttatttagt
    10021 ggataaaaaa ttccctaata tgagagcagg tttcatgcat attccatata tgatggaaca
    10081 agtagtaaat aagccgaata ctgcaggaat gagtctatgt gatattgtaa gaggcataga
    10141 ggtagctatt gaagctattg tagactacaa agataaggat ttgcagttag taggcggtga
    10201 gactcactga taacctaaaa aggatagtca attatgcttg tttactaact attagctatg
    10261 ctaaatcgat tgaggttgtt tacataaaac tctatatcag agaagcctga tatagagttt
    10321 tttcttgcta gttttaggat tttcttgtaa aatagaaaaa gtgaagagag gtatgaaatg
    10381 agcaagaaag ataaaaaaat cgaaattcaa gtagcggatg ccaaagttaa tgttggtaaa
    10441 gacagttttg aaggttatac attgactatc ggtaaaaaag ttatcggaga aattgccgaa
    10501 ttagacggac aatttgccat tataaagaat gggaatgtcg atagttttta taaaaaattg
    10561 gaaaaagctg tggaaatttt gattgaaaat tataatttag caaaataagt cttgtttttt
    10621 tgaaattttc atgatataat agtccatgtt gattgtagga gagatagcga agaggctaaa
    10681 cgcggcggac tgtaaatccg ctccttcggg ttcgggggtt cgaatccctc tctctccatt
    10741 tcattaatgg ggtatagcca agcggtaagg caagggactt tgactccctc atgcgttggt
    10801 tcgaatccag ctaccccagt tcttaggtaa taatcaagat aaaaagcaaa atatcttagg
    10861 gtattttatt tttataattg aaagacgtga atgatatgaa catgtccttg cgggtgctta
    10921 ggaaaaaaat tataagtatg tcaagtttaa gaaaaacttg attgttggag gattttttag
    10981 atgaacgaat ttgaagattt gctaaatagc gttagtcaag ttgagactgg tgatgttgtt
    11041 agtgctgaag tattgacagt tgatgcgact caagctaacg ttgcaatctc tggaactggt
    11101 gttgaaggtg tcttgactct tcgcgaattg acaaacgatc gtgatgcaga tatcaatgac
    11161 tttgttaaag taggagaagt attggatgtt cttgtacttc gtcaagtagt tggtaaagat
    11221 actgatacag ttacatacct tgtatctaaa aaacgccttg aagctcgcaa agcatgggac
    11281 aaacttgttg gtcgcgaaga agaagttgtt actgttaaag gaacgcgtgc cgttaaaggt
    11341 ggactttcag tagaatttga aggtgttcgt ggatttatcc cagcttcaat gttggatact
    11401 cgtttcgtac gtaacgctga gcgttttgta ggtcaagaat ttgatactaa aatcaaagaa
    11461 gttaacgcta aagaaaaccg cttcatcctt tcacgtcgtg aagttgttga agcagctact
    11521 gcagcagctc gcgctgaagt attcggtaaa ttggctgttg gtgatgttgt aactggtaaa
    11581 gttgctcgta tcacaagctt cggcgctttc atcgaccttg gtggtgttga cggattggtt
    11641 cacttgactg aattgtcaca tgaacgtaac gtatcaccca aatcagttgt aactgttggt
    11701 gaagaaattg aagtgaaaat ccttgatctt aacgaagaag aaggacgtgt atcactttca
    11761 cttaaagcaa cagtaccagg accatgggat ggcgttgagc aaaaattggc taaaggtgat
    11821 gtagtagaag gaacagttaa acgtttgact gacttcggtg catttgttga agtattgcca
    11881 ggtatcgatg gacttgttca cgtatcacaa atttcacaca aacggattga aaatccaaaa
    11941 gaagctctta aagttggtca agaagttcaa gttaaagttc ttgaagttaa cgcagatgca
    12001 gaacgcgtgt cactttctat taaagctctt gaagaacgtc cagcccaaga agaaggacaa
    12061 aaagaagaaa aacgtgctgc tcgtccacgt cgtccaagac gtcaagaaaa gcgtgatttc
    12121 gaacttccag aaacacaaac aggattttca atggctgatt tgtttggtga tatcgaactt
    12181 taatcaaatt gaaaattcac aaaatccttt gtttactaaa caagggattt ttctggctct
    12241 ttgtcaactg tagtgggttg aagtcagcta agctcgagaa aggacaaatt tcgtcctttc
    12301 ttttttgata ttcagggcga taaaaatccg ttttttgaag ttttcaaagt tccgaaaacc
    12361 aaaggcattg cgcttgataa gtttgatgag attattggtc gcttccagtt tggcattaga
    12421 atagtgtagt tgaagggcgt tgacaatctt ttctttatct ttgaggaagg ttttaaagac
    12481 agtctgaaaa ataggatgaa cctgcttaag attgtcctca atgagtccga aaaatttctc
    12541 tggttcctta ttctggaagt gaaaaagcaa gagctgatag agttgatagt ggtgtttcaa
    12601 gtcttccgaa taactcaaaa gcttgtttaa aatctcttta ttggttaaat gcatacgaaa
    12661 agtagggcga taaaaatgtt tatcgctgag tttacgacta tcctgttgta tgagcttcca
    12721 gtagcgcttg atagccttgt attcatggga ttttcgatga aactgattca tgatttgaac
    12781 acgcacacga ctcatagcac ggctaagatg ttgtacaata tgaaagcgat caagaacgat
    12841 tttagcattc gggagtgaaa cagcctggga gactgtttca gcctgagcct agaaatttga
    12901 aagcgaagct gtttagccaa gtcatagtaa gggctaaaca tatccatcgt aatgattttg
    12961 acgcgacatc ggacggctct atcatattta agaaagtgat ctcggatgac agcttgtgtt
    13021 ctaccttcaa gaacagtgat gatattgaga ttgttaaaat cttgcgcaat aaagctcatc
    13081 tccatctccc gattgaaaca gtcactcccc ggactgtttc aacgtcccag gacataatct
    13141 caggaagacg cgaaaaatca tgctcaaagt gagaatcatt gagcttgcga atgacagttg
    13201 aagttgaaat ggccagctga tgagcaatat cggtcataga aatcttctca atcaactttt
    13261 gcgcaatttt ttggttgata atacgaggaa tttggtgatt tttcttgacg atagaagttt
    13321 cagcgaccat cattttagaa caatgatagc acttgaaacg acgctttcta aggagaattc
    13381 tagtaggcat accagtcgtt tcaagataag gaattttaga aggtttttga aagtcatatt
    13441 tcttcatttg acttccgcac tcaggacaag atggagcttc atagtccagt ttggcgatga
    13501 tttccttgtg tgtatcctta ttgatgatgt ctaaaatctg gatattaggg tctttaatgt
    13561 ctagtaattt tgtgataaaa tgtaattgtt ccatatgatt ctttctaatg agttgttttg
    13621 tcgcttttca ttataggcca tatgggactt tttttctaca aaaaaatagg ctccataata
    13681 tccatagggg atttacccac tacaaatatt atagagccca aaatcctttg tttactaaac
    13741 aagggatttt tcttttgtct ctgctccttt tttgatataa tagttctatg ttaaaatcag
    13801 aaaaacaatc acgttatcaa atgttaaatg aagaattgtc cttcctattg gaaggcgaaa
    13861 ccaatgtttt ggctaatctt tccaacgcca gtgctctcat aaaatcacgt tttcctaata
    13921 ccgtatttgc aggcttttat ttgttcgatg gaaaggaatt ggttttaggt cccttccaag
    13981 gaggtgtttc ctgcatccgt attgcactag gcaagggtgt ttgtggtgag gcagctcact
    14041 ttcaggaaac tgttattgtt ggagatgtga cgacctatct caactatatt tcttgtgata
    14101 gtctagctaa aagtgaaatt gtggtgccga tgatgaagaa tggtcagtta cttggagttc
    14161 tggatctgga ttcttcagag attgaggatt acgatgctat ggatcgagat tatttggaac
    14221 aatttgtcgc tattttgctt gaaaagacag catgggactt tacgatgttt gaggaaaaat
    14281 cttaatgtat caagcacttt atcgaaaata tagaagtcaa aacttctccc agttagttgg
    14341 tcaagaagtt gtggctaaga ctcttaaaca agcggtggag caagagaaaa taagtcacgc
    14401 ttatcttttt tctggtcctc gtggaacggg aaaaaccagt gttgctaaaa tctttgccaa
    14461 ggctatgaac tgtcccaatc aagtgggtgg cgaaccttgc aataactgct atatttgtca
    14521 agcagtgacg gacggtagtt tagaagatgt cattgaaatg gatgcagctt ctaataatgg
    14581 ggtagatgaa attcgcgaaa ttcgtgataa atctacctat gcgcctagcc ttgctcgtta
    14641 taaggtttat atcatagatg aggttcacat gctgtctaca ggggctttta atgccctcct
    14701 aaagacgctg gaagaaccaa cacagaatgt agtctttatt ttggccacta ctgaattgca
    14761 caagattcct gctactattc tatcccgtgt gcaacgtttt gagtttaaat caattaagac
    14821 acaggatatt aaggaacata ttcactatat cttagaaaaa gaaaatatca gttctgaacc
    14881 agaggctgtg gaaatcattg ccagacgggc ggaaggtgga atgcgggacg ccttgtctat
    14941 tttggatcaa gccctgagtt tgacacaggg aaatgagctg acgactgcta tctctgaaga
    15001 aattactggc accattagcc tatcagcctt ggatgattat gtggcggcct tgtctcaaca
    15061 ggatgttccc aaagctttgt cttgcttgaa tcttcttttt gacaatggta agagcatgac
    15121 tcgttttgtg accgatcttt tgcactattt aagagacttg ttaattgttc aaacaggggg
    15181 agaaaatact catcatagtt cagtctttgt agaaaatttg gcacttcctc aaaaaaatct
    15241 gtttgaaatg attcgcttag caacagtgaa tttagcagat attaagtcta gtttgcagcc
    15301 caagatttat gctgaaatga tgaccgtccg tttggcggaa atcaagcccg aaccagctct
    15361 atcaggagcg gttgaaaatg aaattgctac gctgagacag gaagttgccc gtctcaaaca
    15421 agagctttct aatgcaggtg cggttcctaa acaagttgca ccagctccta gtcgaccagc
    15481 tacgggcaaa acagtctatc gtgtcgatcg caataaagtg caatctatct tacaagaggc
    15541 cgtcgaaaat cctgatttag cacgtcaaaa tctaattcgt ttgcagaatg cctggggaga
    15601 ggtaattgaa agtctaggtg ggccggacaa ggctctgcta gttggttctc aaccggttgc
    15661 tgccaatgaa caccatgcta ttcttgcttt tgagtctaac ttcaatgctg gtcaaactat
    15721 gaaacgagac aatctcaata ccatgtttgg taatatcctc agtcaggcgg caggtttttc
    15781 acctgagatt ttagctattt ccatggagga atggaaagaa gttcgcgcag ccttttcagc
    15841 caaagccaaa tcttctcaaa ctgaaaaaga agtagaagaa agcctgattc cagaaggatt
    15901 tgaatttttg gctgataaag tgaaggtaga ggaagactaa agaaagattt catgatacaa
    15961 taagtttatg aataaacaac aatttattat tatggcgcta tttacagctg ctgagaccta
    16021 ttttttcaat gaagcctgga tgactggccg ctatattatg gcagcctttt gggcaatttt
    16081 actctttaga aatttccgag tcagttatgt gatgggcaaa atcgttgatg tcatcgatca
    16141 gcattttaat aggaaagact agccctcagc ttccagacaa aatcaaagcc ttttaggctt
    16201 ttttttgtta tactagaaaa gtatatttat agaatttttg ctctattttt ggggaaatca
    16261 gacgtttttc tagtaagtac tgtaaaagtt ttgaaaaaga aaggaactat catgtcagta
    16321 ttagagatca aagatcttca tgttgagatt gaaggaaaag aaattttaaa aggggttaac
    16381 ctgaccctga aaacaggaga aattgccgct atcatgggac caaatggtac aggtaaatcg
    16441 actctttctg ccgctatcat gggaaatcca aactatgaag taactaaagg tgaagttttg
    16501 tttgatggcg taaacatcct tgagttggaa gtggatgagc gtgcgcgtat gggacttttc
    16561 cttgctatgc aatacccatc agaaatccct ggaattacca atgctgagtt tcttcgtgcc
    16621 gctatgaatg cgggtaaaga agatgatgag aagatttcag ttcgtgagtt tattactaag
    16681 ctagatgaaa aaatggaatt gctcaacatg aaagaagaaa tggcagagcg ttacctcaac
    16741 gaaggcttct ctggtggtga gaaaaaacgc aatgaaattc ttcaactttt gatgttggag
    16801 ccaacatttg ctcttttgga tgagattgac tcaggtcttg atattgacgc tcttaaagtt
    16861 gtgtctaaag gtgtcaatgc catgcgtggt gaaggttttg gtgctatgat cattactcac
    16921 taccaacgtc ttttgaacta tatcacacct gatgtggtac acgtgatgat ggaaggtcgt
    16981 gttgtccttt ctggtggtcc agaattggct gcgcgtttgg aacgtgaagg atacgcaaaa
    17041 ctagctgaag aacttggcta cgactacaag gaagaattgt aattccctcg tatcttttag
    17101 gagaagtaaa tgactagaga aaatattaaa cttttttcag aaatgcacgc tgaaccaagc
    17161 tggttggctg atctccgtca aaaagctttt gacaagattg agactttgga attaccagtt
    17221 attgagcgtg tcaaattcca ccgttggaat ctgggtgatg gaacgattac agaaaatgag
    17281 ccatcagcaa atgttccaga tttcacagct ttagatcatc acttgaagtt ggtgcaagta
    17341 ggaactcaaa ctgttttcga acaaactcca gttgagttag ctgaacaggg tgttgtcttc
    17401 acagactttc actcagcttt agaagaaatt ccagagctga tcgaagaatt cttcatgtca
    17461 tctgttaagt atgatgatga caagttggcg gcttaccaca cagcttactt taacagtggt
    17521 gctgtactct atattccaga taacgtagaa attacagagc caattgaagg aattttctac
    17581 caagatagcg atagcaatgt gccgtttaac aagcatatta tgattatcgc tggtaaaaat
    17641 tctaagatta gttatctgga gcgtttagag tcacgcggtg aaggaagtga caaagcaact
    17701 gccaatatca cagtggaagt gattgcacgt tctggtgcgc aagtcaagtt tgctgctatc
    17761 gaccgtctag gtgaaaacgt cactgcctac attagccgtc gtggtaaatt aggcgacgat
    17821 gcaagtattg actgggctat cggtgtcatg aacgaaggaa atgtcgttgc tgattttgat
    17881 agtgacttga ttggtaatgg tagccatgct gacctgaagg ttgtagctct ttcaagtggt
    17941 cgtcaggtac aagggattga tactcgtgta actaactatg gctgcaactc tatcggaaat
    18001 atcctacaac atggggttat ccttgaaaaa gcaactttga ctttcaatgg tatcggccac
    18061 atcatcaagg gtgctaaggg agcagatgcg caacaagaga gccgtgttct tatgctttca
    18121 gaccaagcgc gttcagatgc taacccaatt cttttgattg atgaaaatga cgtaactgca
    18181 ggacatgcag cctctattgg tcaggtagat ccagaagaca tgtattacct catgagtcgt
    18241 ggcttggata aggcaactgc agagcgtttg gttgttcgtg gtttccttgg atctgttatc
    18301 gtggagattc cagtcaagga agttcgtgat gaaatgattg caactatcga agagaaattg
    18361 tcaaaacgct aaggggaagc ctatgttaga tgtagaagcg attcgcaagg attttccaat
    18421 tttagatcag attgtcaatg atgaacctct ggtctatctg gacaatgctg cgacgacaca
    18481 aaaaccacta gtagttctga aagctattaa cagctactat gagcaggaca atgccaatgt
    18541 tcaccgtggt gtccatacct tagcggaacg agcgacagct tcttatgaag ctgctcgtga
    18601 aaccattcgt aagtttatta atgcaggctc tacaaaggaa gttctcttta ccagaggaac
    18661 gacaaccagc cttaactggg tggcacgctt tgctgaggaa attctcgctg agggagacca
    18721 ggtcttgatt tcagtaatgg aacaccattc taatatcatt ccatggcagg aagcttgtcg
    18781 aaagactgga gcagagcttg tctatgtcta tcttaaagac ggtgccttgg atatggagga
    18841 tttgcgagct aaattgactg ataaggttaa atttgtttcc ctagctcatg cctccaatgt
    18901 tcttggtgtg gtcaatccga tcaaggaaat cactcaatta gcccaccaag ttggggcaat
    18961 tatggtagtg gatggtgctc aatctacacc tcatatgaag attgatgtcc aggacttgga
    19021 tctggacttt ttcgcctttt cgggtcacaa gatggctggt ccgactggta tcggtgtcct
    19081 ttacggcaaa gaaaagtatc ttgagcaaat gtctccagta gaatttggcg gcgagatgat
    19141 tgattttgtc tacgagcaat ttgctagttg gaaggaattg ccttggaaat ttgaggctgg
    19201 aacgccaaat atggcaggag ctattggact tgcgactgca gttgattatc tggaaaagat
    19261 tggtatggat gccgttgaag ctcatgaaca ggaattgatt gcgtacgtct atccaaaact
    19321 gcaggcaatt gagggattga ccatttacgg ttctcaggat ttggctcaac gttcgggtgt
    19381 tattgccttt aacctaggtg atctccatcc tcacgatctt gcgacggctc tggattatga
    19441 aggagtggct gttcgtgctg gtcaccattg tgcgcaaccc ttgcttcagt atttggaagt
    19501 cccagcaaca gctcgtgcaa gtttttatat ctacaatacc aaggcagatt gcgacaaact
    19561 agtcgatgcc ctacaaaaga caaaggagtt tttcaatggc actttctaaa ctagatagcc
    19621 tttatatggc agtggtagca gaccattcga aaaatccaca tcaccaaggg aagttagaag
    19681 atgctgagca aaccagtctc aacaatccga cttgtgggga tgtcatcaac ctctctgtca
    19741 agtttgatgc agaggaccgt ttggaagata ttgcttttct aaattcagga tgcacgattt
    19801 caactgcttc tgctagtatg atgacagatg ccgttttagg aaaaaccaaa caagaaattt
    19861 tagaactggc gactattttt tctgaaatgg ttcaagggca aaaagatgag cgtcaaggcc
    19921 aacttggaga cgcggcattc ttgtcaggtg ttgccaaatt ccctcaaaga atcaagtgtg
    19981 caaccctagc ttggaatgcc cttaagaaaa caattgaaaa tcaagaaaaa cagtaagaca
    20041 agtttctttt gtcttatgaa ttattagaaa tgaagaaaga aaggatacta tggctgaaga
    20101 aagagtagaa ccaaaaccaa ttgaccttgg tgaatataaa tttggtttcc atgacgatgt
    20161 agagcctgtc ttatcgacag gaaaaggact caacgaaggt gttattcgtg aattatctgc
    20221 tgctaagggt gagcctgagt ggatgttgga gttccgtttg aagtcttatg aaaccttcaa
    20281 aaaaatgccc atgcaaactt ggggagcaga cttgtcagag attgactttg atgacttaat
    20341 ctactaccaa aaaccatctg acaaaccagc ccgttcttgg gatgatgtac ctgaaaagat
    20401 taaagaaacc tttgaacgta tcgggattcc agaagctgaa cgtgcttatt tagcaggggc
    20461 ttctgcccag tacgagtcag aagtggttta ccacaacatg aaggaagagt tccaaaaatt
    20521 aggtattatc tttacagata cagattccgc actcaaggaa tatccagact tatttaaaca
    20581 atactttgcg aagttggtac cgccgacaga taacaagttg gcagccctca actcagcagt
    20641 atggtcgggt ggaactttta tctacgtgcc aaaaggtgtc aaggtagata ttccacttca
    20701 aacttatttc cgtatcaata acgaaaatat aggtcagttc gaacgtacct tgattatcgt
    20761 tgatgaggga gcaagcgtcc actacgtaga aggatgtaca gcaccaacat attcaagcaa
    20821 tagcttacac gctgccattg tagaaatttt tgctttggac ggagcttata tgcgttatac
    20881 aactatccaa aactggtctg ataacgtcta taacttggta acaaagcgtg ctaaggctca
    20941 aaaggatgcc actgttgagt ggattgatgg aaacttgggt gccaaaacga ctatgaaata
    21001 tccatctgtt taccttgatg gagaaggagc gcgtggtacc atgctctcta tcgcctttgc
    21061 taatgcaggg caacaccaag acacgggtgc taagatgatt cacaatgctc cacataccag
    21121 ctcgtctatt gtgtctaaat ccatcgctaa aggtggagga aaggttgact accgtggaca
    21181 agtcaccttt aacaagaact ctaagaaatc tgtttcccac attgaatgtg ataccattat
    21241 catggatgac ttgtcagcat cagatactat tccatttaat gaaattcaca actcgcaagt
    21301 ggctttggaa cacgaagcca aagtatctaa gatttcagaa gagcaattgt attatctcat
    21361 gagccgtgga ttgtcagaat ctgaggcaac tgaaatgatt gtcatgggat ttgtagaacc
    21421 ctttacaaaa gaacttccaa tggaatacgc agttgagctg aaccgcttga ttagctatga
    21481 aatggaggga tcagttggat aaaatttgat tttatactct tcgaaaatct cttcaaacca
    21541 cgtcagcatc gccttaccgt atgtatggtt actgacttcg tcagtttcat ctacaacctc
    21601 aaaacagtgt tttgagcaac ctgcggctag cttcctagtt tgttctttga ttttgagtat
    21661 tagatttact caaaatcaag gattttgaag atgaacttgt atcaaaaaat cgcggtttaa
    21721 aatcgcgatt ttttataatt tctcgttaac aaagcggaca aactgattcc accaaacttt
    21781 taagaagaag gctttttcaa ttttcttgtc tgctatcatt tcgaaactag ggcgctctgt
    21841 ggtgatgtaa ccttgaccaa tcaagttctt gtcttcataa gtcaaatggc caaccactgt
    21901 tccagcttca agtggtgctg ggattgcttt ggaatcaggt gtgaattgaa cagattggga
    21961 agattgattc ccaacacgtt cgattagata gatatcctct ggagccactg cagttactgt
    22021 atcttctttt ccatcttgta caggggcttt gctatcttga taggcatcgc cttgttgaac
    22081 gattttgcga agtgtaaatg tagaagaaat ataatccatt agggaagatg tagctgtaaa
    22141 tcgagcgtaa ggattattgt cttgatgatc tgcatttaaa acaactgtga tgactctcat
    22201 gcctttttcg acagtagtac caacaaaaga ctctccagcc ttatctgttg ttcctgtttt
    22261 tagcccatca aaaccaccac ggtaagcagg cataccttct aacatgtagt tggttgaagt
    22321 gattgtcatc ccagcaaaag tagaagaagg ttttttggtg atttctaaga cttgtgggta
    22381 ttttttgatg aggttgcgag caacgatagc gacatcataa gcactaagct tattttcctc
    22441 atctttttta gaacctgggt aaatgttatc ccctagagtt tcattgttaa gacctgtcgt
    22501 attgacaaca gtggcatcct gaattcccca ttccaagagt tttgcccgca tcatatcgac
    22561 gaaatctttt tctgagccag caattttctc agctagggca atagcggcgc tgttggcact
    22621 agataccaga gttgcttcaa gcaactcttc gacagtataa ttacgggcct ccataggaat
    22681 attactggct tcagaatttg tcgtcaattg ataaggataa tcagaaatat ctacaggagt
    22741 ggagagggta atacttccgt tttccaaagc ttcatagacc agataaacag taatcaattt
    22801 tgttatggaa gcaatttcga caggttgcgt tgcatccttc tcatagagaa ttttaccagt
    22861 atttgcctca acagcaatcg catgtttagc ggcaatggta aaatcttgag caacagcagt
    22921 agaagcaccc cctaaaagag agacagttaa caaagttaaa aatatttttt tcatagtagt
    22981 tttattctat cataaagaaa aaaaatattc ttgctttaat aattcatctg ttaagctttt
    23041 tgaaaatatg gtaaaataaa gtgagggagg taactcatgt ttcgtagaaa taaattattt
    23101 ttttggacca cagaaatttt actcttaacc atcatctttt acctatggag acagatgggg
    23161 tctttgatta acccttttgt tagcgtgctt aatacaatta tgattccatt tttattaggg
    23221 ggctttcttt attatttgac aaaccctatt gttactttct taaataaagt ctgtaaactc
    23281 aatcgtttgc ttggtatttt aattaccttg tgtactttgg tctggggaat ggtcataggt
    23341 gttgtctatc tcttacctat tttgattaat cagttatcta gtttgattat atctagtcaa
    23401 actatttata gtcgagtaca agacttaatc atagacttat ctaattatcc tgcgctccag
    23461 aatttggatg tagaagctac aattcagcag ttaaacttat cctatgttga tattcttcaa
    23521 aatatcctaa atagcgtatc aaatagtgtg gggagcgtct tgtcagctct tatcagtact
    23581 gttttgattt tgattatgac tccagttttt ttggtttatt tcttattaga tggacataaa
    23641 ttcttgccca tgcttgaaag aacgattcta aagagggatc gcttgcatat tgcaggctta
    23701 ttaaagaatt taaatgcgac gattgctcgc tatattagtg gagtttcgat tgacgcaatc
    23761 attataggtt gtttagctta tattggctat agtattattg gtttaaaata tgctttagtt
    23821 tttgccattt tttctggtgt agccaattta attccttatg tggggccaag tattggtttg
    23881 attcctatga tcatcgcaaa tatattcact gatccccata gactgctgat tgcagtgatt
    23941 tatatgcttg ttgttcagca ggtagatggc aatatcttat atcctcgaat cgtaggaagt
    24001 gttatgaagg ttcatccaat cacgatttta gttttacttt tgttgtcaag caatatctat
    24061 ggtgtagttg gaatgattgt cgcagtgcca acctattcta tcttgaaaga aatttctaag
    24121 ttcttatccc gtttgtatga aaatcataaa ataatgaaag aacgagaaag agaattagct
    24181 aagtaaaagt caggagaacc ctgatttttc tttactggaa gtggccttta gattagaaga
    24241 ctgaaaataa gttaaagtct taaactaatt ttcacagcta agaatagtag aagttaatct
    24301 gataaaaatc gaaaaaacca gtggaattcc gtgtcagggt aagttccact ggttttcata
    24361 gtctattaaa gttcgaatga aacctattta tagtagattg aaactagaat agtacacctc
    24421 taattctaaa acattgttag aaatcgattt gactgtcctg atctattcgt cctattctta
    24481 tttcatttta ctatattttg gtgcaataag tgaaaagtag tccgaataat ataaggattg
    24541 attttatagt ttttaaactc aaatgaatta aaataaagag agtacgaaaa ttctcatctg
    24601 aaagtatttt agaataattc tcttcgtgaa tttcttcaaa acagatagct tcatcttagg
    24661 tatgtgttaa ttggatttcg taagctctat ttacaatcgt aaagttatgc actgagaaag
    24721 ttgtagttag tcttccagtt tgctaaattt ctcgaatagt atctttttta ggtatgtgat
    24781 ttctttttgc atttttgagt tagataaggt ataatggttt tattgtcttt tggggtcgtt
    24841 acggattcga caggcattat gaggcatatt ttgcgactcg tgtggcgacg taaacgctca
    24901 gttaaatata actgcaacaa ataacacttc ttacgctcta gctgcctaaa aaccagcagg
    24961 cgtgacccga tttggattgc tcgtgttcaa tgacaggtct tattattagc gagatacgat
    25021 taagccttgt ctagcggttt gataagagat tgatagactc gcagtttcta gacttgagtt
    25081 atgtgtcgag gggctgttaa aataatacat aacctatggt tgtagacaaa tatgttggca
    25141 ggtgtttgga cgtgggttcg actcccaccg gctccattat tcctttgcat tcttttgcat
    25201 tccttggtaa aacgttgtta aatcaacgtt ttttattttt atctttggta ttcatttgca
    25261 ttcttttgct aaaaagggag tcacaaacag accctatttt aaaaaaagga tagaaaaaag
    25321 gatacaacat ttgtcgcatc ctaaaaataa tcttttttcg acggaagaca tgggattcga
    25381 acccacgcac gctattacac gcctaccgcg tttccaacac ggcctcttaa gcctcttgag
    25441 taatcttcca atacttactc aaatagtcta ccataaaggc tcttatcttg caataaaaat
    25501 tctagaaata agaaaaatga tagattttga aagaaaatga taaaaaatgc ttgacttcaa
    25561 aagaaagtat gatagaatga atagtgtaaa cgataacagg aggtgattcg gtgttaaaaa
    25621 cagagcggaa gcaactgatt ttagaggagt taaatcaaca tcatgtagtt tctctagaaa
    25681 aattagttag tttgctagaa acgtcagaat caacggttcg aagagacttg gatgagttgg
    25741 aagcggaaaa caagcttcgt cgtgtgcatg gtggagcaga actcccccat tccttacagg
    25801 aagaagaaac cattcaagaa aaatctgtca aaaaccttca agaaaagaag ttgctggctc
    25861 agaaagcagc ctctctcatt aaagaaaaag atgtcatctt tatcgatgct ggaacaacaa
    25921 ctgctttttt gattcatgaa ttggtcaata agaatattac agttgtgacc aactccattc
    25981 accatgccgc tcagttggtt gaaaagcaga ttccaactgt catggttgga ggaaacgtca
    26041 agacggcgac agatgctagt atcggtggcg ttgctcttaa ccagattaac caattgcact
    26101 ttgaccgtgc ctttatcgga atgaatggtg ttgacgatgg ctattatacg actcctgata
    26161 tggaggaagg agctgtgaaa agagctattt tggagaatgc caagcagacc tacgtcttgg
    26221 tggattcgtc aaaaattgga caaacttgct ttgccaaggt agcaccactc aaacgcgcta
    26281 tcgttatcac tagtcaaggg catgagctct tgcaggttat taaggagaaa acggaggtaa
    26341 tagaagtatg atttatacag tcacactcaa tccatccatt gactatatcg ttcgtttgga
    26401 ccaagtcaaa gttggtagtg taaatcgtat ggacagtgat gataagtttg ctggtgggaa
    26461 aggaatcaat gtcagccgtg tcttgaaacg tttgaatata ccaaatacag cgacgggatt
    26521 tatcggtggc tttactggta aatttatcac agatacttta gcagaggaag aaatcgagac
    26581 acgttttgtc caggtggcag aagatactcg tatcaatgtt aaaatcaaag cagaccaaga
    26641 aacagaaatc aacggaacgg gtccaactgt tgaaccggtt cagctagaag aattgaaagc
    26701 tattttatct agtctgacag cagaagatac agttgtcttt gcaggttcaa gtgctaaaaa
    26761 tctaggcaat gttatctata aggatttgat ttccttgacg cgccagactg gtgcgcaagt
    26821 ggtctgtgac tttgaaggac agaccttaat tgatagtttg gactaccagc ctcttcttgt
    26881 aaaaccaaac aatcatgaac ttggagcgat ttttggggtt aaactcgaaa gtttagatga
    26941 aattgagaaa tacgctcgtg agttactggc taagggtgct caaaatgtta ttatctctat
    27001 ggctggtgat ggcgcccttc ttgtcacatc tgagggagct tacttcgcta aaccaatcaa
    27061 aggaacagtc aaaaattcag ttggagctgg tgattctatg gttgctggat tcacaggtga
    27121 atttgtcaaa tcaaaagacg cagtagaagc cttcaaatgg ggagtggctt gcggaacggc
    27181 aactaccttc tcagatgact tggcaacggc ggaatttatt aaagaaacat atggaaaagt
    27241 tgaggtagaa aaacgatgaa aattcaagat ttattgagaa aagatgtcat gttgctggat
    27301 ttgcaggcaa ctgaaaaaac agctgtcatc gacgagatga ttaaaaattt gacagagcac
    27361 ggttatgtaa cagattttga aacatttaaa gaaggaattt tggcgcgtga agctttgact
    27421 tctactggtt tgggtgatgg aatcgcaatg cctcacagca aaaacgctgc tgtcaaagaa
    27481 gcgacagttc tatttgctaa gtcaaataag ggtgttgact acgagagctt ggatggacaa
    27541 gcaactgacc tcttcttcat gattgcagct ccagaaggtg ccaatgatac tcacttggca
    27601 gccttggcag aattgtctca atacttgatg aaagacggtt ttgcagacaa acttcgtcaa
    27661 gcaacatctg cagaccaagt tatcgaactt tttgaccaag cttcagaaaa aactgaggaa
    27721 cttgttcaag cacctgctaa tgactctggt gactttatcg tagctgttac agcttgtaca
    27781 acaggtattg cccacactta catggcccaa gaagcccttc aaaaagtagc tgctgaaatg
    27841 ggggttggta tcaaggtcga aaccaacggt gctagcggtg ttggaaatca actaactgca
    27901 gaagatatcc gtaaggctaa agctattatc attgcagcag acaaggccgt tgaaatggat
    27961 cgatttgatg gaaaaccatt gatcaatcgt ccagttgctg acggtatccg taagacagaa
    28021 gagctaatta acttggctct ttcaggagat actgaagtct accgtgccgc taatggtgca
    28081 aaagctgcaa cagcctctaa cgaaaaacaa agccttggtg gtgccttcta caaacacttg
    28141 atgagtggtg tatctcaaat gttaccattc gttatcggtg gtggtatcat gattgccctt
    28201 gccttcttga ttgacggtgc tttgagtgtt ccaaatgaaa accttggcaa tcttggttct
    28261 taccatgagt tagcttctat gttcatgaaa attggtggag ctgcctttgg tttgatgctt
    28321 ccagtctttg cgggttatgt tgcctactct attgctgaaa aaccaggttt ggtagcaggt
    28381 ttcgtggctg gtgctattgc caaagaaggt tttgcctttg gtaaaattcc ttatgccgca
    28441 ggtggtgaag caacttcaac tcttgcaggt gtctcatctg gtttcctagg tgcccttgtt
    28501 ggtggattta tcgcaggtgc cttggttctt gccatcaaga aatacgttaa agttcctcgt
    28561 tcactcgaag gtgctaaatc aatccttcta ttgccacttc ttggaacaat cttgacagga
    28621 tttgttatgc tagctgtgaa tatcccaatg gctgcaatca acactgctat gaatgacttc
    28681 ctaggcggtc ttggaggagg ttcagctgtc cttcttggta tcgtccttgg tggaatgatg
    28741 gctgttgaca tgggtggacc agttaataaa gcagcttatg tctttggtac aggtacgctt
    28801 gcagcaactg tttcttcagg tggttctgta gccatggcag cagttatggc tggaggaatg
    28861 gtgccaccac ttgcaatctt tgtcgcaact cttcttttca aagataaatt tactaaggaa
    28921 gaacgtaact ctggtttgac aaacatcatc atgggcttgt catttatcac tgagggagcg
    28981 attccatttg gtgccgctga cccagctcgt gcgattccaa gcttcatcct tggttcagca
    29041 gtagcaggtg gactcgttgg tcttactggt atcaaactca tggcgccaca cggaggaatc
    29101 ttcgttatcg cccttacttc aaatgctctc ctttacctcg tttctgtctt ggtaggagca
    29161 atcgtaagtg gtgtggttta tggttaccta cgcaaaccac aagcataaaa aatagaaaaa
    29221 tgaaaagatt ggaccgtttg gtgcagtctt tttctcttcc cgaaatgcct gtgaaatatg
    29281 gtataataga agaatggcaa acaagaatac aagtacaaca agacggagac cgtctaaagc
    29341 agaactggaa agaaaagaag cgattcaacg aatgttgatt tcgttaggaa ttgcgatttt
    29401 attgattttc gcagccttca aattaggggc tgcaggtata accctttata atttaattcg
    29461 cttgctagtg ggtagcctag cttatctggc gatattcggc ctattaatct atctcttctt
    29521 tttcaagtgg atacgaaaac aggaaggact cttatctggc tttttcacca tatttgctgg
    29581 cttactcttg atttttgagg cctacttggt ttggaaatat ggtttggaca agtccgttct
    29641 aaaagggacc atggctcagg ttgtgacaga tctgactggt tttcgaacga ctagttttgc
    29701 tggagggggc ttgatcgggg tcgctcttta tattccaaca gcctttctct tttcaaatat
    29761 cggaacttac tttattggtt ctatcttgat tttagtgggt tctctcctag tcagcccttg
    29821 gtctgtttac gatattgctg aatttttcag tagaggcttt gccaaatggt gggaagggca
    29881 cgagcgtcga aaagaggaac gctttgtcaa acaagaagaa aaagctcgcc aaaaggctga
    29941 gaaagaggct agattagaac aagaagagac tgaaaaagcc ttactcgatt tgcctcctgt
    30001 tgatatggaa acgggtgaaa ttctgacaga ggaagctgtt caaaatcttc cacctattcc
    30061 agaagaaaag tgggtggaac cagaaatcat cctgcctcaa gctgaactta aattccctga
    30121 acaggaagat gactcagatg acgaagatgt tcaggtcgat ttttcagcca aagaagccct
    30181 tgaatacaaa cttccaagct tacaactctt tgcaccagat aaaccaaaag atcagtctaa
    30241 agagaagaaa attgtcagag aaaatatcaa aatcttagaa gcaacctttg ctagctttgg
    30301 tattaaggta acagttgaac gggccgaaat tgggccatca gtgaccaagt atgaagtcaa
    30361 gccggctgtt ggtgtaaggg tcaaccgcat ttccaatcta tcagatgacc tcgctctagc
    30421 cttggctgct aaggatgtcc ggattgaagc accaatccct gggaaatccc taatcggaat
    30481 tgaagtgccc aactccgata ttgccactgt atctttccga gaactatggg aacaatcgca
    30541 aacgaaagca gaaaatttct tggaaattcc tttagggaag gctgttaatg gaaccgcaag
    30601 agcttttgac ctttctaaaa tgccccactt gctagttgca ggttcaacgg gttcagggaa
    30661 gtcagtagca gttaacggca ttattgctag cattctcatg aaggcgagac cagatcaagt
    30721 taaatttatg atggtcgatc ccaagatggt tgagttatct gtttacaatg atattcccca
    30781 cctcttgatt ccagtcgtga ccaatccacg caaagccagc aaggctctgc aaaaggttgt
    30841 ggatgaaatg gaaaaccgtt atgaactctt tgccaaggtg ggagttcgga atattgcagg
    30901 ttttaatgcc aaggtagaag agttcaattc ccagtctgag tacaagcaaa ttccgctacc
    30961 attcattgtc gtgattgtgg atgagttggc tgacctcatg atggtggcca gcaaggaagt
    31021 ggaagatgct atcatccgtc ttgggcagaa ggcgcgtgct gcaggtatcc acatgattct
    31081 tgcaactcag cgtccatctg ttgatgtcat ctctggtttg attaaggcca atgttccatc
    31141 tcgtgtagca tttgcggttt catcaggaac agactcccgt acgattttgg atgaaaatgg
    31201 agcagaaaaa cttcttggtc gaggagacat gctctttaaa ccgattgatg aaaatcatcc
    31261 agttcgtctc caaggctcct ttatctcgga tgacgatgtt gagcgcattg tgaacttcat
    31321 caaggctcag gcagatgcag actacgatga gagttttgat ccaggtgagg tttctgaaaa
    31381 tgaaggagaa ttttcggatg gagatgctgg tggtgatccg ctttttgaag aagctaagtc
    31441 tttggttatc gaaacacaga aagccagtgc gtctatgatt cagcgtcgtt tatcagttgg
    31501 atttaaccgt gcgacccgtc tcatggaaga actggagata gcaggtgtca tcggtccagc
    31561 tgaaggtacc aaaccaagaa aagttttaca acaataaaaa aatagcttct ttccaagttt
    31621 ggaaggaggc tattttagtg attattgatt agttttattt tccgaagttg gggtattgga
    31681 ctgtttttcg ttttcagtag caggtttact tggagtagga gcaggagtag aagaatcctg
    31741 agttgatgtt ttctgctctt cttttttctc ttccttgacg ctggattttg gcgtttcttc
    31801 ttgttgtgtt ttttcttgag aagtcttatt ttccttattg ggactagtat tttcctgagg
    31861 ggattccttt tgaatttctt tgacaattgt tgtcgtctgg cttgttgtag gttccttttt
    31921 agtatttttg ttattatcca aggcgttcat aatcgtgata ctagcggtaa tcaagccaag
    31981 gatactagcg atagtcgcaa cggttttttg aaagactgta aagccttttt tgatgtgttc
    32041 tgtttttggt tttgaagttc tacgataatt agacatacat tctctccttt gattatgact
    32101 tattatactc tgtttcttta aaaaaatctt aaaaaaagag aaattgccct ttcttgtcgc
    32161 aagctccgtt tcatgataca atagagggag tgattttaga aagcgtgaga aacatgattt
    32221 actttgataa ttcagcgacg accaagcctt atcctgaagc ccttgaaacc tatgtgcagg
    32281 tcgcttcaaa aattttagga aacccatcta gtctccatcg tttgggagac caagcaacac
    32341 gaatcttaga tgcttctcgc caacagattg cagatttaat cggtaagaaa agcgatgaaa
    32401 tcttctttac ctctggtgga acagaagggg ataactgggt tatcaagggt gtggcctttg
    32461 aaaaagctca gtttggcaag cacatcattg tttcagccat tgaacatcca gcagtcaaag
    32521 agtcagccct ctggttgaaa agtcaaggat ttgaagtgga ttttgctcca gttgataaga
    32581 aaggcttggt cgatgttgag gcgttagcag gtttgatacg gcctgataca atcctcgttt
    32641 ccatcatggc tgtgaacaat gaaatcggct ctatccaacc tattgaggct atttcagaat
    32701 tcttggcaga caagccgact atttccttcc acgttgatgc ggttcaggcg cttgccaaaa
    32761 ttccgactga aaagtatctg acagaacggg tggattgcgc gaccttctcg agtcataaat
    32821 ttcatggtgt ccgtggtgtt ggctttgtct atatcaaatc tggcaagaag attacacctc
    32881 ttcttacagg tggtggccag gagcgagatt atcgttcgac aactgaaaat gtggcaggga
    32941 ttgcagcgac agccaaggcc ctccgtttgt ctatggaaaa gctagatatc tttaggagca
    33001 agactgggca gatgaaggca gtgattcgcc aagctcttct gaactatccg gatatttttg
    33061 tcttttcaga tgaggaaaac tttgcacctc atattctgac ttttggaatc aaaggtgttc
    33121 gaggtgaagt catcgttcac gcctttgaag actatgatat tttcatctca acaacctcag
    33181 cttgttcatc taaggcagga aaaccagccg ataccttgat tgccatggga gtggacaaag
    33241 ataaggccaa gtcagctgtg cgtcttagcc tagacttgga aaatgatatg agtcaggtcg
    33301 agcagttttt gaccaagtta aaattgattt acaatcaaac tagaaaagta agataggagc
    33361 attcatgcag tattcagaaa ttatgattcg ctacggagag ttgtcaacca agggtaaaaa
    33421 ccgtatgcgt ttcatcaata aacttcgtaa taatatttcg gacgttttgt ctatctatac
    33481 ccaagttaag gtaacagcag atcgcgaccg tgcccacgct tacctcaatg gagctgatta
    33541 cacagcagtt gcagaatctc tcaaacaagt ttttggaatt caaaactttt ctcctgttta
    33601 taaggttgaa aaatctgtag aagttttgaa gtcttctgtc caagagatta tgcgggacat
    33661 ctacaaggaa ggtatgacct ttaagatttc tagcaagcgt agcgaccaca actttgaact
    33721 tgatagtcgt gaactcaacc aaacacttgg aggggctgta ttcgaagcca ttccaaatgt
    33781 gcaagttcaa atgaaaagtc ctgacatcaa tcttcaggtg gagattcgtg aagaagcagc
    33841 ctatctttct tatgaaacca ttcgtggggc tggtggtttg ccagttggaa cttcaggtaa
    33901 agggatgctc atgttgtcag gagggattga ctcacctgta gcaggttatc ttgctcttaa
    33961 gcgtggggtg gatatcgagg cagttcactt tgctagtcca ccatatacta gtcctggtgc
    34021 cctcaagaaa gcgcaggact tgacccgtaa attgaccaag tttggcggaa atatccagtt
    34081 tatcgaggtg cctttcacag agattcaaga ggaaatcaaa gccaaagcgc cagaagctta
    34141 tttgatgact ctaactcgtc gctttatgat gcggattact gaccgtattc gtgaggtacg
    34201 aaatggtttg gttatcatca atggggaaag tctaggtcaa gtagccagcc aaacccttga
    34261 aagtatgaag gctatcaatg ctgttaccaa cactcccatc attcgtcctg tggttaccat
    34321 ggacaagttg gaaatcattg acatcgccca ggaaatcgat acctttgaca tttcaatcca
    34381 accgtttgaa gactgttgta ccatttttgc accagatcgt ccaaaaacaa atcctaaaat
    34441 taagaatgcg gagcagtacg aagcgcgtat ggatgttgaa ggcttggttg agcgagcagt
    34501 ggctggaatc atgattactg aaatcacacc tcaagccgaa aaagatgaag ttgatgactt
    34561 gattgacaat ctgctctaat tcagaaaatc caaaagaata gcgaaaatca gtaaaaaaag
    34621 ttagtttttt ctctaaaaac aggtaaaaaa ctaacttttt ttatttttat gatataatga
    34681 tataaaattt tgaatataga gagttttctg acaatgaatc aatcctactt ttatctaaaa
    34741 atgaaagaac acaaactcaa ggttccttat acaggtaagg agcgccgtgt acgtattctt
    34801 cttcctaaag attatgagaa agatacagac cgttcctatc ctgttgtata ctttcatgac
    34861 gggcaaaatg ttttttatag caaagagtct ttcattggat attcatggaa gattatccca
    34921 gctatcaaac gaaatccgga tatcagtcgc atgattgtcg ttgctattga caatgatggt
    34981 atggggcgaa tgaatgagta tgcggcttgg aagttccaag aatctcctat cccagagcag
    35041 cagtttggtg gtaagggtgt ggagtatgct gagtttgtca tggaggtggt caagcctttt
    35101 atcgatgaga cctatcgtac aaaagcagac tgccagcata cggctatgat tggttcctca
    35161 ctaggaggca atattaccca gtttatcggt ttggaatacc aagaccaaat tggttgcttg
    35221 ggcgtttttt catctgcaaa ctggctccac caagaagcct ttaaccgcta tatcgagtgc
    35281 cagaaactat cgcctgacca gcgcatcttc atctatgtag gaacagaaga agcagatgat
    35341 acagacaaga ccttgatgga tggcaatatc aaacaagcct atatcgactc gtcgctttgc
    35401 tattaccatg atttgatagc agggggagta catctggata atcttgtgct aaaagttcag
    35461 tctggtgcca ttcatagtga aatcccttgg tcagaaaatc taccagattg tctgagattt
    35521 tttgcagaaa aatggtaagt taagaaagga aaaaacgaaa tgcatattga acatcttagc
    35581 cactggagtg gtcatcctaa ccgtgaaatg taccttaacc gttatggaca tggtgggatt
    35641 ccagttgtgg tctttgcttc atcaggtggt agtcacaacg aatactatga ttttggcatg
    35701 attgatgcct gtgcttcctt tatcgaggaa ggccttgtcc agttctttac cctatctagt
    35761 gtggatagtg agagctggtt ggctacttgg aaaaatgctc atgaccaagc ggaaatgcac
    35821 cgtgcctacg aatgttatgt gattgaggag gccattcttt tatcaagcac aagacaggtt
    35881 ggtttgatgg catgatgacg acaggttgct ctatgggagc ctatcatgca ctcaatttct
    35941 tcctccagca tccagatgtc tttaccaaag tgattgctct cagtggtgtt tacgacgcac
    36001 gtttctttgt cggtgattac tacaacgatg atgctattta ccaaaactcg ccagtagatt
    36061 atatttggaa ccaaaacgac ggctggttta ttgaccgtta ccgtcaggca gagattgtgc
    36121 tgtgtacggg gcttggagcc tgggaacaag atggtttgcc atccttttac aagctcaaag
    36181 aagcctttga caagaaacaa attccagcct ggtttgctga atggggacat gatgtcgccc
    36241 atgactggga atggtggcgt aaacaaatgc cttatttcct cggtaatctc tatttataaa
    36301 aggagttacc tatgaattac cttgttattt ctccctacta tccacaaaac tttcaacagt
    36361 ttaccatcga actagctaat aaaggcatca cagtcttggg aattggtcaa gagtcttacg
    36421 agcaattgga tgagcccttg cgcaatagct tgaccgagta ttttcgtgtt gataatcttg
    36481 agaacataga tgaagtcaaa cgtgcagttg cttttctctt ttataaacat ggtccaattg
    36541 accgcatcga gtctcacaat gaatactggc ttgagctaga cgcaacactc agagaacaat
    36601 tcaatgtttt tggtgccaaa ccagaggatc tcaaaaagac gaaatataag tctgaaatga
    36661 agaaactttt caaaaaagca ggtgttcctg tggtacctgg agctgttatc aagacggaag
    36721 cagatgttga tcaagcagtg aaagaaatcg gtcttccaat gattgccaaa cctgataatg
    36781 gagtgggagc agccgcaacc tttaaacttg agacagaaga cgatatcaat cacttcaagc
    36841 aagaatggga ccattcaacc ctttatttat ttgaaaaatt tgtcacttcc agcgaaatct
    36901 gtacctttga cgggctcgtg gacaaggatg gaaagattgt cttctcaaca acctttgact
    36961 acgcctatac accgcttgac ctcatgattt ataagatgga caattcttat tatgtgctca
    37021 aggatatgga tcctaaactg cgcaagtatg gggaagcaat tgtcaaagaa tttggtatga
    37081 aagaacggtt tttccatatt gagttcttcc gtgaggggga cgattatatt gccatcgagt
    37141 acaataaccg ccctgcaggt ggttttacca ttgatgttta taactttgct cattccttgg
    37201 acctttatcg tggctatgca gctattgtag caggagagga gttcccggcg tcagactttg
    37261 aaactcagta ttgtttggct acttctcgcc gtgcaaatgc tcactatgtt tattcagaag
    37321 aggatttgct tgccaaatat agccagcagt tcaaggttaa aaaagtcatg ccagctgcct
    37381 tcgcggaact tcaaggagat tacctgtata tgctgaccac tccgagtcga caagaaatgg
    37441 agcagatgat tgcagatttc ggacaacgtc aagaataaga actatcggat taaggaaatt
    37501 aactccctta atccttttgt tttgtctgat aaaaaataag agcatcccaa caaggtagct
    37561 atcataaaac ttgttcgata actatttgaa gcaggattag gtggtcagaa attaaatttt
    37621 aatatttcaa ttgagtcata gtattgtgtt tgcgtatcct taaatcagct aaaaggatcc
    37681 atgacgacac ctatacgata tagttttcaa gataccaaac aagtctatta atattcaatg
    37741 aaaatcaaag agcaaactag gaagctagcc gcaggtttct caaaacactg ttttgaggtt
    37801 gtggatagaa ctgacagagt cagtatcata tacctacggc aaggtgaagc tgacgtggtt
    37861 tgaagagatt ttcgaagagt ataaaatatt caggtgacgc atagatatag ttaattgaag
    37921 ctttgtttga aatctgataa aataatgata ttactaagtt ttaaaaacta aagaaaaggg
    37981 aagatatgat tacaggcgaa ttaaaaaata aaatcgatca gctgtgggaa attctttgga
    38041 cagaaggaaa cgcaaatcct ttaacaaata ttgaacagtt gacttatctc ttatttatga
    38101 aagatttgga tagtgtcgag cttggacgtg aaagtgatgc tgaatttcta gggattcctt
    38161 atgagggagt ttttccaaaa gataaacctg aataccgttg gtcaactttt aaaaatatag
    38221 gagatgctca ggaagtttat cgtttaatga ctcaggagat ttttccgttt attaaaaatc
    38281 tcaaggggga tacagatgat acagcctttt cacgatatat gcgagaagct atttttcaaa
    38341 taaataaacc tgctacgctt caaaaggcaa tttctatctt agatgttttt ccaactaggg
    38401 gattagatgt agattttgat aatgacaaac aaagtattac tgatatcgga gatatctatg
    38461 aatatctgtt atcaaaattg tcgaccgcag gtaaaaatgg acagttccgt acacctcgtc
    38521 acatcatcga tatgatggtt gagttgatgc aaccgactat caaagatatc atctcagatc
    38581 ccgctatggg ttctgctggc ttcttagtat ctgctagccg ttacttaaag cgtaagaaag
    38641 atgaatggga aaccaataca gataatatca atcattttca taatcagatg tttcatggaa
    38701 atgatacgga tacgactatg ttgagacttg gggcgatgaa catgatgcta catggagtag
    38761 aaaatccaca aatcagttac cttgactcgc tgtctcaaga taatgaagaa gccgataaat
    38821 atactttggt tttagcaaat cctcctttta agggttcact tgactacaat tcaacttcta
    38881 atgaccttct tgcaaccgta aaaaccaaaa aaacagaatt actctttctt tctcttttct
    38941 tgcgaacttt aaaaccaggt ggacgagcag cagttatcgt acctgatggt gtcctttttg
    39001 gttcgtctaa agctcataaa ggaattcgtc aggaaattgt agagaatcat aagcttgatg
    39061 ctgtaatctc aatgcctagt ggtgttttca agccttatgc tggagtttca actgccattc
    39121 tcatctttac aaaaactggt aatggtggta ctgacaaagt ctggttttac gatatgaaag
    39181 cggatggttt aagtttggat gataagcgac aaccgattag cgacaatgat attccagata
    39241 ttatcgaacg ctttcatcat cttgaaaaag aagcagaacg tcagagaacg gatcaatctt
    39301 tctttgttcc agttgctgag ataaaggaaa atgattatga tttgtctatc aataaatata
    39361 aagagattga gtatgaaaaa gttgagtatg aaccaacaga ggtcatctta aagaaaatca
    39421 atgatttaga aaaagaaatt caagctggct tggctgaatt agaaaaatta ctcaagtaga
    39481 gaggtggctg tatgaaaaaa gtgaagttgg gggaagtctt atctctaaaa aaaggcaaga
    39541 aagccactgt acttgctgaa caaacaactc taagccaacg ttatattcaa atagatgatt
    39601 taagaaataa taataattta aaattcactg aaagtttaaa tatgactgaa gcactcccag
    39661 atgatattct gatagcatgg gatggagcta atgcaggaac agttggttat ggattatcgg
    39721 gagctgttgg tagtacaatt acggtcttaa aaaagaatga gcgatacaaa gaaaaaatta
    39781 tatcagatta cttgggagtc tttttggaaa gtaaatcgca gtatttacga gaacattcaa
    39841 caggtgcaac aattcctcat ttaaacaaga atatattact tgatttacaa ttagaattgc
    39901 taggtatcga agaacaagag aacattatct gtattcttaa tacgattaaa aggcttatta
    39961 ctaaaagaaa attgcagtta gatgaactaa acttgctcgt caaatcccga tattccgagg
    40021 aggtggttgc atgaagaaag tgaaattagg ggaagtggct acttttatca atggctatgc
    40081 ttttaaacct caagattggt catctgaagg gagagagatt atcagaatac agaatctgac
    40141 taaaacttca acagagataa attattattc gggtacgatt gataaaaaat acattgttga
    40201 agctggtgat atccttattt cgtggtcggg tacattaggg gtttttcagt ggtgtggaag
    40261 atccgcagta ttaaatcagc acatttttaa agtggttttt gataagatag atatagataa
    40321 atcgtatttt aaatatgttg ttgaaaaagg tttacaagat gctgtaaaac atactcatgg
    40381 ttccacaatg aaacatttaa ctaaaaaata ttttgataat attatagttc catatacaaa
    40441 tttgggagag caacaaagaa ttgcaagtga gctggatttg ttaagcaagc tgattttaag
    40501 gagacaagaa caacttgaag agcttaatct acttgtaaaa tcccgattta acgagatgtt
    40561 tggggaaaat aaaatatttg aaagcattga taacttattt gatattatag atggtgatag
    40621 gggcaaaaat tatcctaaat cagatgagtt gtttagtgag gagtactgtt tatttttaaa
    40681 tacaaagaat gttactaaaa acggattttc attcgataca aagcaattta tcactaaaac
    40741 aaaggataaa ttacttcgaa aaggcaaact tgagcgttat gatatagtct tgacaacaag
    40801 aggtactgtt ggaaatgtag cgtactacga tgaattaata aaatataaac atttacgtat
    40861 aaattcaggt atggtaatat tacgtcccaa gacaccaaat ctaaatcaca attggcaatc
    40921 caaaaatctc tggaagaact tgaaactttg aagaaatctc tgatgcagga gtattttggc
    40981 tgatattctg ccattgtaat tacggtaatg atttgttata atacttcaaa ggaggaaatc
    41041 agatggtagt aaaaacaaga aaacaaggaa attcaatcac cattacgatt ccaagtgaat
    41101 ttaatattcc aagtggtgtt aaatacgaag cgaaattgtt accaagtggt gagattatct
    41161 ttactcctga agaattgggg cagcaggttt cttatgtatc tgatgatgcc tttgacttaa
    41221 atttagataa aatatttgac gaatacgacg atgttttcaa agctttggtg gaaaaatgac
    41281 aatctatctg acagaaaagc aaattgaaaa aataaatgct ttagcaattc aacggtattc
    41341 tccaaatgag aaaattcaaa cagttagttc ttctgcctta aatatgattg tgaacttacc
    41401 agaacaattt gtctttggga agtctcttta tccaacaatt tttgataaag caacgatact
    41461 atttgtccaa ttgataaaga agcatgtttt tgctaatgct aataaaagaa ctgctttctt
    41521 cgttttggtc aaatttttac aattaaacgg ctatcgtttt tctgtaacgg tagaagaagc
    41581 agtaaaaatg tgtgtaacca tcgcagtaga agctttaact gatgaaaaaa tgacaagcta
    41641 ctccaaatgg gtttctgaac attctgttag agaaaaggtc aaaaagtaac ctagtatgct
    41701 ggatttgaat gagcacaaga aaataaatga acagacaata ttagaattct gtaatgcaga
    41761 aactgatatt gtctcttttt attgatgaat aagaaagtga gaaattatgg aatcaaaagt
    41821 tacaattatc atgcaagaaa tgttacctct tttaaataat gaacaattac tagcgttgag
    41881 agagagttta gaacatcatc tagtagacgg aaaaaagcag cagaagtatt cgaataataa
    41941 cctgttgcaa ctatttatta ccgccaagca ggtagagggc tgtagctcaa aaacaattcg
    42001 ttattaccag aggacgattg aaaacttgtt taatgctatt aaagagtctg tgacacaact
    42061 cacaacagat gatttaagga gttatttagc aaattaccag tctgaaaagg attgtagtaa
    42121 ggcaaattta gacaatatta ggcgtatatt gtcttctttt tttgcttggc ttgagcaaga
    42181 ggaatatatc attaaaaatc ccattcgacg gataaagaaa attaagactg agcaaaatgt
    42241 gaaggaaact tatactgatg aacatttgga aattatgcgt gataactgtg aaaatttgag
    42301 agatttggca ataatagacc tactagcatc gacaggtatg cgtgtagggg agcttgtaca
    42361 gttgaatcgt tcagatattg attttgaaaa cagagagtgt gttgtctttg gtaaaggaaa
    42421 gaaggagaga ccagtatatt ttgatgctcg gacgaaaatt catttaagaa attatcttaa
    42481 cgacagaaaa gatagtcacc ctgctctttt tgtaacgcta gttggaaaag cccagagact
    42541 tggaattgct ggtgtagaga ttcgcttaag aaagttagga gacaaactcg gcatacaaaa
    42601 ggttcaccca cataagttca gaagaacttt agcgactaag gcaattgata aaggtatgcc
    42661 tatcgaacaa gtccaaaaac tgctaggtca tagcaagatt gacacaaccc tggcctatgc
    42721 catggtcaat caaaataatg tcaagcattc acaccaaaaa ttcatctctt aaaagcaaaa
    42781 tcccgattta acgagatgtt tggggatgtt attctaaatg aaaaagaatg gaaagttagc
    42841 aaatggaacg agattctaac aataagaaat ggtaaaaatc aaaaacaggt tgaagatgct
    42901 gatgggaaat ttcctattta tggaagtggg ggaattatgg gatatgctaa agattggata
    42961 gtgaagaaaa attcagttat tattggacgt aaaggaaata taaataaacc tattttagtt
    43021 agagaaaatt tttggaatgt agatacagca tttggattag agcctgtttt agaaaaaata
    43081 aactcagaat atttattcta tttttgtcaa ttatacaatt ttgagaagtt aaataaggct
    43141 gtaacaatac ctagtttaac taaatcagat ttattaaata tttccatccc cctcccccca
    43201 ctagccctcc aaaatgagtt cgcagacttt gtagtccagg tcgacaaatc acaaatttat
    43261 tatccatgtt ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca
    43321 gttaccaatt acaaaattaa aaaaaatact tctctccctt cccccactag ccctccaaaa
    43381 tgagttcgca gactttgtag ccctggtcga caaatcagaa tttgcttgtg agatagctat
    43441 aaaagtgtgg agaaatagct tgaaatttag tataatatag ctaaactatt tgtttaaagt
    43501 gagaaaaaaa tgggaaattt tagctttctt ttaaaaaatg acgaatatga atctttttca
    43561 aaaccttgca ttgaagctga gaatatgatt gctacatcaa ctgtggctac tgcctttatg
    43621 gcgcgtcgtg ctttagagca ggctgtccat tggatatata gtcacgattc atatttagaa
    43681 gctccctatc gtgctactct atcttcttta gtatgggatg atgattttag ggatatcgta
    43741 gattctgaac tccacaagca gatagttctg ttgattcggt ggggaaacca tgctgctcat
    43801 ggtggtgaaa ttaaggaacg agaagcgatt ttagctttgc atcatttgta tcagtttgtt
    43861 aattttatcg attattgtta cagcaatgag tttgtggagc gttattttga tgagaagtgc
    43921 ttaccacttt cagcaaacat caaataccga gaaactccac aatctatgat aaagttacaa
    43981 gacagtttac cagaactgcc tgattttcat gaacagatgg ctgctcagtc cgtagaagtt
    44041 caagagactt atactgaaaa acgtgaaact gcagcgcaac ggcaagatgt gcctttccat
    44101 attgatcaat tatctgaggc agagacaaga aagctcttta ttgatatcga tctccgttta
    44161 gcaggatgga tatttgaaga aaactgtcgt gttgagatag ccgttgatgg tctcaagcac
    44221 ggttcaggaa ttggttactg tgactatgta ctttatggta aaaatgggaa aattttagcg
    44281 attgtggagg ctaaaaaagc ctctgtcaat ccagaagtag gggaagtaca ggtcaaagaa
    44341 tatgctgaag ctttggagaa acatatcggc tatcagccaa tttgctttat tacaaatggg
    44401 ttgaagcact atatacttga tggtccgaac cgccgccaga ttgcaggctt ttactctcaa
    44461 gaagaattgc aattagtgat ggatagacgt catcttcaaa aaccgcttga ggatatttct
    44521 agtaaaatta gggacgatat ttccgggcgt cactaccaaa aacatgccat tgcaagcgtt
    44581 tgtgaagctt tctctaatca tcgtagacag gcacttttgg ttatggcaac tggggcgggg
    44641 aaaactcgta cagcagtttc tctagttgat atcttatcac gtcataactg ggtaaaaaac
    44701 gttctcttct tagccgatag aacttccttg gttaagcaag cctatgattc gtttagaaaa
    44761 ttactcccag atctttccgt ttgtaacttc ttagaagata aagaaggagc tcaatcaagt
    44821 cgcatggtct tttcaactta tccgaccatg attggagcga ttagtggtca agaagaagta
    44881 aatcaacgcc ctttcactgt tgggcatttt gaccttatca taattgacga atctcaccgt
    44941 tctatttatc agaaatacaa gtccattttt gattattttg atgcaaggat tgtaggctta
    45001 acagctactc cgcgtcaaga tttagataaa aacacctatg gattctttaa tttggagaat
    45061 ggggttccaa catatgcata tgatttggaa gaggctgtta aagacggata tttagtagcc
    45121 tatcattcta tcgaaaccaa actgaaacta cctacggatg gtctacatta tgatgatttg
    45181 tccgaagaag aaaaggaaca ttttgatagc aaatttgaag acgatagctg tgaaaaagat
    45241 attgatggga gtgtatttaa ttcctttatt ttcaataaaa gtacagtaga aattgtttta
    45301 aatgaactca tgacaagagg aattcagaca gcctcgggtg atgaaattgg taaaactatt
    45361 atttttgcta aaaatcatga tcatgcggaa tatatcagag atatttttaa caaccgctat
    45421 cctgaaaaag ggagcgacta tgctcaggta attgattata gtattaagca ttatcagacc
    45481 ttgattgatg attttaaaat taaggagaag tatcctcaaa ttgcgatttc tgtagatatg
    45541 ttagatacag gtattgatgt accagaggtt gttaatttag tcttcttcaa gaaagtacgc
    45601 tctaaaacta agttttggca gatgattggt cgaggaaccc gtctgtgtaa agatttattt
    45661 ggacctgagc aggataagga aaacttcttg gtatttgatt atggggacaa ttttgattat
    45721 tttcgtgcag atccaagaga tggagagggt cgtcacattg tttcgttgac tcagcgttta
    45781 tttaatatca aagtggactt gattcgagaa cttcagggac tccaatacca agaagatcag
    45841 tttgcgagag cataccgtca gcagcttgtc tcggaacttc aaggtcgtat agagagctta
    45901 aatgagttgg acttcagggc tcgtatggtt ttagatacag tttatagcta taggaaattg
    45961 gaaagttggc agaatctaac tgctgttaca agtgaaacca ttcaaaaaaa tctttctccg
    46021 cttttatttg atgaagataa agaagatgag atggcgagga gatttgattt gtggttgctt
    46081 catattcagt tggggcaact gacagctaaa tcttccactg ttcatatttc ccaagtgatg
    46141 aagacggcta gagctctttc tgctattggc aatatcccgc aggtttttga gcaggctgaa
    46201 attatcagga aagtacagga acctgaattt tggaaagaag ttaacttgtc tgatttggaa
    46261 aaaattcgtc ttgctattcg agatttatta cagtttttgg ataaaacaga ccgtaaaccc
    46321 tactatgtta actttgaaga tcgtatactc tccactgttc acgagaccac agcatttttg
    46381 caggtcaacg atcttcggtc ttacaatgaa aaagttgagc attatttgaa aactcatctg
    46441 gatgaggagt ccatttctaa gctataccat aataaaaagt tgacatctga tgatatgctt
    46501 gcacttgaaa aattgctctg ggaaaaatta ggtagtaaag cagactacca aagtcattat
    46561 gaaaataagg caattccgag attggttcgt gagattattg gtttagatag agagtctgcc
    46621 aatcgtattt tttctaaatt tttgtcggat gagaatctta atgccaggca gatttcattt
    46681 gtaaaattga ttgtagacta cattgtagaa aatggttttt tagagacgaa agtgttaacg
    46741 caagagccgt ttaaatctta tggttctgtt caactactct tccaacacca actaccagta
    46801 cttcgtaata ttgttcaaat cattgaactt atcaataatc gagctggaga agcggcttaa
    46861 attctaaagt gattgccatg ctgagactca tttaaaatta aaaagagtag aaatttatgc
    46921 tatatatgag aagttttatt aggaagaatg tcatcgtttt cctagaatac agtatcagtt
    46981 gttaagtggt tgataaattt caaagtagat acttgtacca cgatgtttgt tgatcgagtt
    47041 attaacaaaa gagctacttt gattttaaag aaatagaaaa caaaaagccg agcaagaatt
    47101 caattgcagg agaaaatgaa ataatactca atgaaaatca aagagcaaac taggaaacta
    47161 gctgcaggct gctcaaaaca ctgttttgag gttgcagatg gaagctgacg aagtcagctc
    47221 aaaacatggt tttgaggttg t
//
LOCUS       DAVMJI010000014        46906 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.014, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000014 DAVMJI010000000
VERSION     DAVMJI010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.014"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            173..826
                     /locus_tag="VYR58_000941"
     CDS             173..826
                     /locus_tag="VYR58_000941"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV3622124.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            836..1300
                     /locus_tag="VYR58_000942"
     CDS             836..1300
                     /locus_tag="VYR58_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV3622125.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1313..2581
                     /locus_tag="VYR58_000943"
     CDS             1313..2581
                     /locus_tag="VYR58_000943"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV3622126.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     NATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2595..2855
                     /locus_tag="VYR58_000944"
     CDS             2595..2855
                     /locus_tag="VYR58_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622127.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2866..4227
                     /gene="pdrM"
                     /locus_tag="VYR58_000945"
     CDS             2866..4227
                     /gene="pdrM"
                     /locus_tag="VYR58_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV3622128.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4381..5349
                     /locus_tag="VYR58_000946"
     CDS             4381..5349
                     /locus_tag="VYR58_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV3622129.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5365..6357
                     /locus_tag="VYR58_000947"
     CDS             5365..6357
                     /locus_tag="VYR58_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV3622130.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6575..7618
                     /locus_tag="VYR58_000948"
     CDS             6575..7618
                     /locus_tag="VYR58_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV3622131.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7682..9367
                     /gene="lpdA"
                     /locus_tag="VYR58_000949"
     CDS             7682..9367
                     /gene="lpdA"
                     /locus_tag="VYR58_000949"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV3622132.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9431..10420
                     /locus_tag="VYR58_000950"
     CDS             9431..10420
                     /locus_tag="VYR58_000950"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV3622133.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10493..11563)
                     /gene="xerS"
                     /locus_tag="VYR58_000951"
     CDS             complement(10493..11563)
                     /gene="xerS"
                     /locus_tag="VYR58_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV3622134.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAKNIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(12057..13607)
                     /locus_tag="VYR58_000952"
     CDS             complement(12057..13607)
                     /locus_tag="VYR58_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV3622135.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNILITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13623..14402)
                     /locus_tag="VYR58_000953"
     CDS             complement(13623..14402)
                     /locus_tag="VYR58_000953"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV3622136.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14389..15240)
                     /gene="ylqF"
                     /locus_tag="VYR58_000954"
     CDS             complement(14389..15240)
                     /gene="ylqF"
                     /locus_tag="VYR58_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV3622137.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15512..20725)
                     /locus_tag="VYR58_000955"
     CDS             complement(15512..20725)
                     /locus_tag="VYR58_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV3622138.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNMDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(20769..27248)
                     /locus_tag="VYR58_000956"
     CDS             complement(20769..27248)
                     /locus_tag="VYR58_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV3622139.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPS
                     AEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHN
                     FINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVI
                     KLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQ
                     YQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVY
                     DELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENY
                     FMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKT
                     QQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGT
                     NNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHA
                     DGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLID
                     KSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLW
                     DPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEI
                     LTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEK
                     VYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVPMKDKEVISDINKNKSSIN
                     KLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALN
                     SVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKV
                     IDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNV
                     IELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQT
                     KAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFII
                     ANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEK
                     LYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGD
                     AFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPN
                     DPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAV
                     AKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIIT
                     RRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMV
                     PYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKERED
                     KFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRV
                     LKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            complement(27457..28635)
                     /locus_tag="VYR58_000957"
     CDS             complement(27457..28635)
                     /locus_tag="VYR58_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622140.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLLLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(28850..32500)
                     /gene="addA"
                     /locus_tag="VYR58_000958"
     CDS             complement(28850..32500)
                     /gene="addA"
                     /locus_tag="VYR58_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV3622141.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TIRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(32497..35772)
                     /gene="rexB"
                     /locus_tag="VYR58_000959"
     CDS             complement(32497..35772)
                     /gene="rexB"
                     /locus_tag="VYR58_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV3622142.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            complement(35972..36127)
                     /locus_tag="VYR58_000960"
                     /pseudo
     CDS             complement(35972..36127)
                     /locus_tag="VYR58_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            36280..37131
                     /locus_tag="VYR58_000961"
                     /pseudo
     CDS             36280..37131
                     /locus_tag="VYR58_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            37031..37477
                     /locus_tag="VYR58_000962"
     CDS             37031..37477
                     /locus_tag="VYR58_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV3622143.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(37615..38919)
                     /gene="eno"
                     /locus_tag="VYR58_000963"
     CDS             complement(37615..38919)
                     /gene="eno"
                     /locus_tag="VYR58_000963"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV3622144.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            39083..39529
                     /locus_tag="VYR58_000964"
     CDS             39083..39529
                     /locus_tag="VYR58_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV3622145.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(39526..40329)
                     /locus_tag="VYR58_000965"
     CDS             complement(39526..40329)
                     /locus_tag="VYR58_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV3622146.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGID
                     TCLDLINFDKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAED
                     LPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(40338..40983)
                     /gene="serB"
                     /locus_tag="VYR58_000966"
                     /pseudo
     CDS             complement(40338..40983)
                     /gene="serB"
                     /locus_tag="VYR58_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931944.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
     gene            complement(41042..42475)
                     /gene="glgA"
                     /locus_tag="VYR58_000967"
     CDS             complement(41042..42475)
                     /gene="glgA"
                     /locus_tag="VYR58_000967"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV3622147.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYCWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(42472..43611)
                     /gene="glgD"
                     /locus_tag="VYR58_000968"
     CDS             complement(42472..43611)
                     /gene="glgD"
                     /locus_tag="VYR58_000968"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV3622148.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVELGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(43601..44743)
                     /locus_tag="VYR58_000969"
     CDS             complement(43601..44743)
                     /locus_tag="VYR58_000969"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV3622149.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(44733..46661)
                     /gene="glgB"
                     /locus_tag="VYR58_000970"
     CDS             complement(44733..46661)
                     /gene="glgB"
                     /locus_tag="VYR58_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV3622150.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELREKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT        13587 a         9551 c         8812 g        14956 t
ORIGIN      
        1 tgcttaatga tttaaaaagt aattataaaa aatagccagt ctttataaac tgtattcacg
       61 tattcaaatc gtatatatag tcgatttatt aaatctttag ataaactgta aaaagtggtt
      121 tccatagcca ctttttgcta taatagaggc agtaaaaatg aaggagtcag ctatggaaca
      181 ctcgtcttgg catgctttga ttaaggcgca attacctgag ggttatttcg ggaaaatcaa
      241 tcagtttatg gagcaggtct attctcaggg gattatttat ccacccaagg aaaaggtttt
      301 tcaggctctc ttgacaacac tgcttgaaga agttaaggtg gtaattctag ggcaagaccc
      361 ctatcacgga ccaggtcaag cgcagggctt gagtttttct gtacctgact ctatcccagc
      421 tccaccatcc ttgcaaaata tcttgaaaga attgtcagat gatatcggag ttaagaaatc
      481 tcatgatttg acagcttggg ctgagcaagg agtcttgctt cttaatgctt gtttgactgt
      541 tcctgctgga caggccaatg gtcatgctgg tcaaatctgg gagcctttta ctgatgctgt
      601 gattcaggtg gtcaatcatc tagatagacc agtcgttttt gtactctggg gagcttatgc
      661 acgtaagaag aaggccttag ttaccaatcc tcatcacttg attattgaat cagcccatcc
      721 aagtcctttg tcggtttata gaggattttg gggttccaag cccttttcca aggccaatgc
      781 attcttaaaa gagacaggac aagagccaat cgattggctt agataaggag aaaatatgcc
      841 tcagttagcg acgatttgct acattgataa tgggaaagaa ctgctcatgc tccatcgtaa
      901 taagaaaccc aatgatgtcc atgaagggaa atggattggt gtgggtggta agctagagag
      961 aggagagacg ccccaggaat gcgcggcgcg tgaaatcctt gaagaaacag ggctcaaagc
     1021 caagccagtt ctaaaaggtg tcatcacttt tcctgaattt acaccagatt tagactggta
     1081 cacctatgtt tttaaggtga cggagtttga gggcgacttg attgactgca atgaggggac
     1141 gctagaatgg gttccctatg acgaggtttt gagcaagccg acttgggaag gtgaccacac
     1201 ctttgttgag tggcttttag aggataaacc cttcttttca gccaagtttg tttatgatgg
     1261 ggataaattg ttggataccc aagttgattt ctatgaataa aggagaaagc agatgctact
     1321 aatcaaaaat ggtcgtgtaa tggatcctaa gtctggtttg gatcaagttt gtgatgtctt
     1381 agttcaagat gggaaaatta tcaaaattgc gcctgagatc acggaagaag gagcagaaac
     1441 gattaatgct actggtcttg tggttgctcc tggtttggtc gatattcatg tgcatttccg
     1501 tgaacctggt caaacacata aagaagacat tcatactggt gccctagcag ccgctgcagg
     1561 tggttttact actgtcgtca tgatggctaa taccagtcca accatttcag acgtggagac
     1621 tttgcaagca gttctccagt cagctgccaa agagaagatt aatgtcaaga cagttgcgac
     1681 cattactaaa aactttaatg gtaaaaactt gactgacttt aaggcgctct tagaagctgg
     1741 tgcggttggt ttctctgatg acggtattcc gcttgagagc agtaagattg tcaaggaagc
     1801 catggaggaa gccaaaaaac tcaatacctt tatcagcctt catgaggaag atccaggttt
     1861 gaacggtgtt cttggcttta atgaaaatat tgctagagaa cattttcata tctgcggtgc
     1921 tactggggtg gctgagtacg ctatgatggc gcgtgatgtc atgattgcct atgcaactaa
     1981 agcccatgtt cacatccagc atttgtctaa ggaagaaagt gttaaagtag tggagtttgc
     2041 tcaggggtta ggtgcagaag tcacagcaga agtagcgcca cagcatttct ctaagacaga
     2101 agcacttctt ttaacacaag gtagcaatgc taagatgaat ccaccgcttc gtttggaatc
     2161 agaccgtcgt gccgttatcg aaggtctcaa atcaggtgtc atcacagtta ttgcgactga
     2221 ccacgcgcct catcatgtag atgaaaaaaa tgttgaggat attaccaaag cgccatctgg
     2281 tatgactggc ttagaaacat ccctgtctct cagcttgacc tatttagtag aagctggtga
     2341 gttgagcttg atggaattac ttgaaaaaat gacatacaac ccagccaagc tttacaactt
     2401 tgaagcaggt tacttggctg agaatggtcc agcagatatc actatttttg atgccaaggc
     2461 tgaccgcctt gtggactccc attttgcttc caaagcagct aattcaccat tcatcggtga
     2521 aaccttaaaa gggcaggtta aatataccat ctgtaaggga caaatcgtct atcaagcttg
     2581 ataggagtta gaatatgaat tattttcgaa aacgtaggga gagacaagcg aaatctaata
     2641 gtggaattta ctgtcccgca gctaatcgtt ccaaaattca atatgaaact aaagaaaaag
     2701 ctgaccatgc ggttcaatat gataacggag gtttagttag aagctattat tgtcgtacat
     2761 gtgcgtgttg gcatactact tcaaaatcta ataaacctcc gctaagtttg aaaaactatg
     2821 gtctgaaact ctttggttta gataaatcag aatagaaaga gaagtatgta taagacaaag
     2881 tgtttacgag agaagttagt attattttta aaaattttct tcccaatact gatctaccaa
     2941 tttgccaatt attctgcctc ttttgttgat actgcaatga caggtcaata caacactatg
     3001 gacttggctg gtgtatctat ggcaaccagt atctggaatc ctttctttac atttctaaca
     3061 gggattgtgt cagccttggt gcctatcatt ggtcaccatc ttggtcgagg aaaaaaggaa
     3121 gaagttgcgt ctgattttta ccaatttatt tatttggcct tgggcctatc tgtggtcttg
     3181 ctggggatgg tacttttctt ggcaccaaca atcttgaatc atattgggtt agaagcagca
     3241 gtagcggcag tagcggttcg ctatctttgg tttttatcta tcgggattat ccccttgttg
     3301 ctctttagcg tcattcgttc cttgctggat tcgctgggct tgaccaaact gtccatgtac
     3361 ctcatgcttt tgttactccc tctcaatagc ggatttaact atctcttgat ttacggtgcc
     3421 tttggtgttc cagaactggg aggggctggt gctggtttag gaacatcctt ggcctactgg
     3481 gtcttgcttg ggatttctgt tctggtttta tttaaacagg agaagctcaa agccttacac
     3541 cttgagaaac gaattccact taatatggat aaaattaagg aaggagttcg tttaggtctg
     3601 cctattgggg gaactgtctt cgcggaagtg gctgtctttt cagtggttgg cttgattatg
     3661 gctaagtttt cgtccttgat tatagctagt caccagtcag ctatgaactt ttcaagtctt
     3721 atgtacgcct ttcctatgag tatctcatcg gctatggcta ttgtcgtttc ctatgaagtg
     3781 ggagccaagc gatttgatga tgcgaaaacc tatattggtc taggaagatg gactgccctc
     3841 atttttgcgg ccttcacctt aaccttcctt tacattttta ggggaaatgt ggccagtctt
     3901 tatggtaacg acccaaaatt tatcgatttg acagcgcgtt ttttaactta tagtcttttc
     3961 ttccagttag cagatacctt tgcggcgccg cttcagggaa ttttgcgggg gtataaggat
     4021 acagttattc ctttttacct tggtttgctt ggttattggg gcgtagcaat ccctgtggct
     4081 acgctatttg attccctaac agattttgga gcttattctt actggatcgg cttgattatt
     4141 agtttgattg tgagcggggc gctctaccgt tggcgtttaa ctgtgattat gaagagattt
     4201 gaatctttag caaaatccaa acgctaaaaa gtttgtgaaa aaatattctt gacaagaaaa
     4261 tcccttgttt tcacggggtt ttctttttta ttttgtgaaa tttcttttag aaaaactttg
     4321 acagtatttg ccaaaagcgg taaaatagta aggtaagaag aaagttagaa aggcaagaag
     4381 atgtcaactt tagataaaaa tcttttgcta gaaatgttcc gtaagatgga agaaatccgt
     4441 cgcatggact taaaaattgc acaattagta aagaaaggga aagtgccagg aatgacgcac
     4501 ttttctgttg gtgaagaggc agctaacgtg ggggctatgt tagctctcaa tccagatgat
     4561 ctgattacct caaaccaccg tggacacggg caagctattg ctaaagggat tgacctcaac
     4621 ggaatgatgg ctgaaatcct tggtaaatac actggaacct gtaaagggaa aggtggatct
     4681 atgcatatcg ctgaccttga tgctgggaac cttggtgcca atggtatcgt aggtggtggt
     4741 atggggatcg ctgtcggtgc agccctcagt cagcaaatgc aaaataccgg taaaatcgtt
     4801 gtttgcttct ttggagatgg tgcgaccaat gaaggtgttt tccacgaagc agtgaacatg
     4861 gcttctatct ggaacctgcc agtcattttc tattgcatta acaacggtta cggtatctct
     4921 gcggatatca agaaaatgac caatatagaa catatccatc aacgtagcgc cgcttatgga
     4981 attcctggaa tgttcatcga agacggtaac aatgtcatcg atgtctatga aggatttcag
     5041 aaagctgtag accatgttcg cagtggcaat ggttcagtct tgattgaaag tgtaacttat
     5101 cgctggctcg gtcactcatc atctgaccct ggtaaatatc gtacgcgtga agaagtggaa
     5161 ttgtggaaac aaaaagatcc aatcgaaaac ctccgcaatt accttattga aaataacatt
     5221 gcaagtgccg aagaattgga agaaatccaa gcgcaagtaa aggaagcagt agaagcttct
     5281 gttaaatttg cagaggaaag cccattccca ccgcttgaat cagcctttga agatatttac
     5341 gcagactaag gagaaagaga taaaatggaa acaaaaacaa tgtccttccg tgacaccatt
     5401 atccttgcta tgtctgagga aatgcgtcgc gatgaaaatg tgttcttgat gggagaagat
     5461 gtcggtgtct tcggaggaga cttcggtact tctgttggaa tgcttgaaga atttggtcca
     5521 gaacgtgtcc gtgactgtcc gatttctgaa gctgccatct ctggagcagc agcaggagca
     5581 gccatgacag gacttcgtcc aatcgtcgat atgaccttca tggacttctc tgttattgcc
     5641 atggacaata tcgtcaacca agctgctaaa acacgttaca tgtttggtgg taaaggtcag
     5701 gttccaatga ctgttcgttg tgcagctggt aacggagttg gctctgccgc ccagcactca
     5761 caatctctag agtcttggtt tactcacatt ccaggactta aggttgtggc acctggaaca
     5821 cctgcggaca tgaaaggcct gcttaagtct tctatccgtg ataacaaccc agttattata
     5881 cttgagtaca agtcagaatt taaccaaaaa ggggaagtgc cagttgatcc agactacaca
     5941 attccacttg gggttggtga aatcaaacgc caaggaacgg atgtaacagt tgttacttat
     6001 ggaaaaatgc ttcgccgtgt ggttcaagct gctgaagaat tagcagaaga agaaatttca
     6061 gttgaaattg ttgacccacg tacccttgtt ccgcttgata aggatatcat cataaactca
     6121 gtgaagaaga ctggtaaggt tattctggtc aacgatgccc acaaaacaag tggctatatc
     6181 ggtgaaattt cagctattat ttcagaatca gaagcatttg actatctaga tgcaccaata
     6241 cgccgttgtt caggagaaga tgtgccgatg ccttatgcac aaaacctaga aaatgcaatg
     6301 attccaacag ttgaaagtat caaagatgca atccgaaaaa cttataacaa agactagagt
     6361 tacataatat aagttatgta actaaaataa agctgacgag aaactttgta tcttttaggt
     6421 gcagagctct tcgtcattaa tatcttatat tcgagcacgg gctaaaagct cggaaaaaag
     6481 ataaatctcc ttggcttcat cgaagccatc gtcgatttcc tatttttcag tcgcttttga
     6541 cgccctttgt atcataaata gaattggaga ggtcatggct gatgacaagc taagagcgac
     6601 tcctgcagct agaaagttag cggatgattt agggataaac ctctacgacg tttctggctc
     6661 aggtgcaaac ggtcgtgtcc acaaagaaga cgtggaaact tataaagaca caaacgtggt
     6721 tcgcatttcg ccacttgcaa aacgaattgc cctcgaacat aacattgctt ggcaggaaat
     6781 ccaaggaacc ggtcatcgtg gtaaaatcat gaagaaggat gttttggccc tgcttcctga
     6841 aaatatcgaa aacgatagca tcaaatctcc tgctcagatt gaaaaagtgg aagaagtccc
     6901 tgataacgta acaccatatg gtgaaatcga gcgtattcca atgacaccaa tgcgtaaggt
     6961 tattgcccaa cgcatggttg aatcttactt gactgcgcca accttcaccc tcaactatga
     7021 agttgatatg actgaaatgt tggctcttcg taagaaggtt cttgagccaa tcatggaagc
     7081 aactgggaag aagactactg taacagacct tctttcgctt gcagttgtta agactcttat
     7141 gaaacaccca tacatcaacg cttcattgac agaagatggc aagactatta tcactcacaa
     7201 ctatgtcaat cttgccatgg cagttgggat ggataatgga ttgatgacac ctgttgttta
     7261 caatgctgag aagatgagtc tttcagaact ggtggtagcc tttaaggatg ttattggccg
     7321 taccttggat ggtaaattgg ctccaagtga gttacaaaat tcaacattca caatcagtaa
     7381 tttgggaatg tttggtgttc agtcctttgg tccgattatt aaccaaccca actcagctat
     7441 ccttggtgtc agttcgacaa tcgagaagcc agttgtcgtc aatggtgaaa ttgtgattcg
     7501 cccaatcatg agtttaggat taaccattga ccaccgtgtc gtagatggta tggctggtgc
     7561 taagtttatg aaggacttga aagagttgat tgaaacgcca atctcaatgt taatttaaga
     7621 gcaagagtat tcatttttaa gatatagata aaggaaggaa gacatggcct tagaaataat
     7681 tatgccaaaa gccggcgtgg atatgacaga aggacaaatc gtccaatgga ataaaaaagt
     7741 cggagaattt gtaaaagaag gagaaatcct tttggaaatc atgactgata aagtcagcat
     7801 ggaattggaa gccgaagaag atgggtactt gattgccatt ctcaaaggag atggtgaaac
     7861 tgtccctgta acggaagtta tcggttacct tggtgaagaa agggaaaaca tcccaacagc
     7921 tggagcagca tcgccagaag ctagccctgt acctgtagca agtacctcaa acgatgatgg
     7981 taagagcgat gatgcttttg atatcgttgt gattggtgga ggtcctgctg gttatgttgc
     8041 agccattaaa gctgcccaac tcggcggtaa ggttgccctt gttgagaaat ctgaacttgg
     8101 tggaacctgc ttaaaccgtg gatgtattcc aaccaagacc taccttcata gcgctgaaat
     8161 tattgaaaat atcggtcatg ctgcaaatcg tggtatcgtg attgaaaatc ctaacttcac
     8221 tgttgatatg gaaaaacttt tagaaactaa atctaaagtt gttaatactc ttgttggtgg
     8281 tgttgcagga cttcttcgta gctacggagt tgctgttcat aaaggaattg gtacaatcac
     8341 taaagacaag aacgtcttgg taaatggttc tgaattgctt gaaaccaaga aaatcattct
     8401 tgctggtggt tcaaaagtca gcaagatcaa cgtccctggt atggaatctc cacttgtcat
     8461 gactagtgat gacattcttg aaatgaacga agtgccagaa agccttgtta tcatcggtgg
     8521 tggagttgtc ggtatcgaac tcggtcaggc cttcatgaca tttggttcaa aagtgactgt
     8581 tatcgaaatg atggaccgta tagttccagc tatggatgtg gaagtttcta agaaccttcg
     8641 cttgatcctt gagcgtaaag gaatgaccat cttgactggt actaaactgc aagaaatcat
     8701 tgaggaaaat ggtcaacttc gtatcaaggt tgaaggaaaa gacgatatca tcgcaagcaa
     8761 agctcttctt tcaattggtc gtatgccaga ccttgaaggt attggagagg ttgagtttga
     8821 attggatcgt ggttgtatca aggtcaacga atacatggaa acttcagttc caggcattta
     8881 tgcaccaggt gacatcaacg gtactaagat gttggctcac gcagctttcc gcatgggtga
     8941 agtttccgct gaaaatgccc ttaaaggaaa tcatgcagtt gccaaattga atttgactcc
     9001 tgcagccatc tacactcttc ctgaagtagc agcagtaggt ttgacagaag aacaagcccg
     9061 tgagaaatac gatgttgcca tcggtaagtt taactttgct gctaacggtc gtgctattgc
     9121 atctgacgca gctcaaggtt tcgtaaaagt tatcgctgat aagaaatacg gagaaatcct
     9181 tggtgtacac attattggtc ctgcagccgc agaattaata aacgaagcat caagcatcat
     9241 cgaaatggaa atcactgttg aggaaatgct gaagaccatc cacgggcacc caacttactc
     9301 tgaagtgatg tacgaagcgt ttgcagatgt tctaggaatg gccatccatt cacctaagaa
     9361 aaaataaaac gaagatagat tagactggaa ggttatttcc agtttctatc atataaagta
     9421 aagggatatc atgaaataca ttatcaatca ttcaaatgac actgctttta atattgcctt
     9481 ggaagaatac gcctttaaac accttttgga tgaggatcaa atcttcctac tttggattaa
     9541 caagccatct atcattgttg gtcgtcacca gaacactatt gaagaaatca accgtgatta
     9601 tgttcgcgaa aatggtattg aggtagttcg ccgtattagt ggtggtggag ctgtttacca
     9661 cgatttaaat aacctcaact acacgatcat ctccaaagaa gatgaaaata aggcatttga
     9721 cttcaagagc ttctcaactc cggttatcaa taccttggct caactcgggg ttaaagctga
     9781 gttcacaggt cgtaatgacc ttgagattga tggtaagaag ttctgtggca atgcccaagc
     9841 ctatatcaac ggccgtatca tgcaccacgg ttgcttgctc tttgacgttg atttgtcagt
     9901 cctcgcaaat gcccttaagg tttcaaaaga taaatttgaa tcaaaaggtg tgaaatccgt
     9961 ccgtgcccgt gtaaccaata ttatcaatga attaccaaaa aaaatcacag tcgaaaaatt
    10021 ccgtgattta ctcttggaat acatgaaaaa agagtaccca gagatgactg aatacgtctt
    10081 ttcagaagaa gaattggccg aaatcaatcg catcaaggat actaagtttg gaacttggga
    10141 ctggaactat ggtaaatcac ctgaatttaa cgtccgtcgt ggaaccaaat tcactagtgg
    10201 taaggttgaa gtctttgcta acgttactga atcaaaaatc caagacatca agatttatgg
    10261 tgacttcttt ggtattgaag acgttgctgc agtagaagat gtccttcgtg gggtgaaata
    10321 cgaacgcgaa gatgttctta aggcgctaaa aaccattgat atcacacgct acttcgctgg
    10381 tattagccgt gaagaaatcg ctgaagcggt agttggataa atcaaaaaga agttggccaa
    10441 ctaaccaact tctttttttg atatttattt acataattta aaatacgtaa aatcataaac
    10501 tatccagagc attcttttgt tcatcactaa caatatgggt atagaggtca gtgacttgtg
    10561 tgctagcatg tcctagttgg tgactgacta aaacttgtga tttagtcgca tcatagagcc
    10621 tagttgctag tgtatggcgc agtttatggg gtgttacacg cactttaaaa tcctctgagt
    10681 atttagcaac cattttctca acgctagaag catcgatacg attaggaaca cctctgtaga
    10741 gagttaaaaa aagggctgta tctgtttttt ccgttttata gcgttgattc cgaatggcca
    10801 gataattctc taaataaggt ttagcaaaag cagcgacatt gactgagtca cgtttgccac
    10861 cttttcgagt aacatcaata accatcattt ttagattgag atctcttaga tctagattaa
    10921 cagcttcaga taagcgaaca ccagatgcca agagaagggc aataatggct aaatctcgtt
    10981 ctttattttt gttgaatgat gagagagctc gatttgaaag ctgttgtggg tgctcttgat
    11041 cgatataagt tagaaaacct tctgtttcat cacctagaaa gagtttttgc ttgatatttt
    11101 tagctctggc agcaagggtt tctttctttt tcttggttga aacttttttc attacattac
    11161 gatagaaata aggttccccc tgatcgtttt caacctcttc ggttagatac ttgtaaagac
    11221 tagaaagtgc tgataaggtt cgattgatag ttgtctgtga aacaccttgt tttgttgtat
    11281 tagcattcag caagggacgt tcacgtagat aaaggataaa ggattccatg tctttcttag
    11341 acatattttc caaaactgat aaaggaatat cggatatttt atcagcgttt gaaataccag
    11401 actccaaaac ccagctgaaa aatcggtcat attccttaag gtattcgtac agggttgtaa
    11461 aactgtaggg cacagccagc ttagattggt agtattccag aacataccag ggcatgagtt
    11521 gttttagttt gtcgattcgt tccagtaaaa tctcacgttt catgtatttt ctccataagt
    11581 aagtatacta gtagtatagc atagacttgt atatttttca agaaaattat agtttttcag
    11641 aaagatgtta taggagtttt tcaaagtgat aaaaagactt agacctacaa acaaaacaga
    11701 ataaggaaaa taataaaaat ctcacccact aaacttctgt taatactaca tagctagaaa
    11761 ttgatttgat tgtcctgatt gttttatcct atttctattt catttcacta tataattgct
    11821 attgttttct ttttcatgat tttaatctta ctgtacagat ttgatacagt aaactccttt
    11881 ctagctttat gctttatcat ttctaactta attatagtct tatttttaat aaagttcaat
    11941 tatttatatg taaaattcct catcagtaaa aaataaccga tctcatttct gagaatcggt
    12001 tttctaaata aatcaaaccg atcatttaca taacataaat tatgtaaatg atcatactac
    12061 aacaacaaat ctttgacttt tccaatttca ctttttggaa taaccaggtg aatcatatca
    12121 cccagataca ttctggttga gccgttaact gtttggctct tgccattatg gacttgagtt
    12181 gtgatgagga tgttgtgtgg taagttgagt tcatgaactt gtttcccagc aattttatca
    12241 gaaactggta tttcgataag tgtaacttct ccttcgctag atacttcttc tggaagcatt
    12301 ttttccagca tggcttcata gactggcgta cctttgagca aatccatgat aatataagaa
    12361 acaagagtga caagaccaag tggcataagg ttgcgaatat ctcctaccat ctcagttacg
    12421 aggatcatag cggttaaggg agcttttgat atggctccaa aatagccact cattcctaga
    12481 atgacaaata tagggaattg ctcttgactg acaagtccaa gattgacaca gataacacca
    12541 actaaggcac caagcaaaga accaagagct aaaatgggga ggaaaattcc tcctggcagt
    12601 ccacttccat agctaatcat actccaaata aagcggatta aaaagtaagc taataaaact
    12661 tggaaactaa aattttgttc agttaaagaa aggacaagct gatttccgcc accaatgatt
    12721 tgaggtaaga agattccgac tggtatgata aggataaaag ccaagatggg ataataagcc
    12781 ctatccaaat ggattttttg accaatcaag tcataaactc ttccaacgtt taatacagct
    12841 ttctcataga gaaaacctga aaatccaagg aaaattccca tgacgagata tatccaatac
    12901 tggtctaggg tcatgggagg aatgttatct ggcatatcca atactggtgt caaaccgaac
    12961 atgagtagag acacaaagtt tgctacgatg ctggctgcta gagttgagac ccagaaaaag
    13021 cgcgaaaaat ggtgatagac ttcttctaca acaaagagaa gtgctgcaat aggagcatta
    13081 aaggctgcgg ctaaacctgc tgcagctcca ctggcaatca aggaacgttc ctctactgga
    13141 ctggatttga gccacttggc aattccttta ccaccaactg ctccaagttg aatgctgggt
    13201 ccctctcgac ccagcatgag tccactggca atagcaagaa tacctagcac atattttttc
    13261 caaagaatgc cccaccagtt gagggacatg aggcctttca gttcggcttc gacttgagga
    13321 attcctgagc ctttaatatc tttttctgac cgtgttagtt tggcactgag ccaacagatg
    13381 agtatataaa acaaaaccag tacaaaaaga ttgcgcacta agtacccttg atcttgataa
    13441 actccttgta tcaggtggaa gcccttttca attaagaaac gaaaggatcc gacgataatt
    13501 ccaacgatga ggccgacaat gattcctcga ccaacttggg atagtatagt gctggatgca
    13561 aaggcgaatt ctttcttaga acggactatt tccgactgtt cctccatggt atttcctttc
    13621 aattaacttt cttttttacc taaaaccagt gatttaacgg gttcaaagct ggttcggtga
    13681 attggggtaa ctcctagttt tgtgaggcct tccagatgtt tagctgtgcc atatcctgca
    13741 ttagtagcga aatcatagcc agagaactgc tgatcgtatt ctttcatcaa ttcatcacgt
    13801 gttaccttgg ctactataga tgctgctgcg atagagaggg agttggcatc tcctttgata
    13861 atggaggttt gtgaaatggg caagtccagt ttcatggcat caatcaaaag gtgctctggt
    13921 tgagggctga gctgggagat tgcttcttgc atggctagtt tggttgcttc atagatgttg
    13981 acttggtcga tgacctgatt atctatgata ccaattccaa tcgacaaggc ttggtcttga
    14041 acggcttgga aaatctccag atgtttcttt ttaggaattt tcttgctgtc gttgagacct
    14101 ttaatcttac aatttttagg taaaataacg gccgcagcga ctacaggacc agcaagagga
    14161 ccacgaccaa cctcatcaat acctgcaatt aaggtcaatc cttgcttata aagttctttt
    14221 tcataagaaa gcatggattc caagcgcaaa ttttcatcta attcagcttg aatggctctt
    14281 ttacgcttgc tgatttcctt ttgaactcct gagcgattat ccttttcaag ctctaaaaaa
    14341 atagggcttt ctaactcctt gactgtcaca aggagttctt tgatttcttt aatcgttgcc
    14401 atcgaggtct tccaatgtat ctaaggtata gttaccgagt ttgccatcac ggacttcctt
    14461 cacgaagaga ctgtaaaaac ggtcatagtc atcacggaaa ccgagggcgc gggtcatatc
    14521 cataataatc acaggcgctt cttcttcaat tttcatttgt ttgaagcgtt cagccagctt
    14581 ttctggataa tgttctttga aataattgat accaaaaatg gtaacctcat ccataggaag
    14641 caactgatcc ttgatagctc cagtcaatgc caacttaagt gcaacagttt catcctcaaa
    14701 cttaggccag agaatccccg gtgtatccaa gatttccaga tctttattgg ttttaagcca
    14761 ttgttgacct tttgtgaccc ctggcttgtt tccaacaaca gcaatctttt taccagccaa
    14821 acggttcatc agagttgatt taccagcgtt tggaatccca ataatcatgg tacgcaaggt
    14881 ttcaatctga atcccacgtt ctttctggcg agcaatctta tcagccatga gcttcttggc
    14941 cgcatctgtt acaactttta cagtcacttg ctctttggag ttgatagcta gcgtctggat
    15001 tccttgtgat tcaaaatact gacgccattc cttggtcatt gctggatcag ccaagtcggc
    15061 cttgtttaaa atcaagagtt ttggtttatc accaacaatc ttggtcaaca taggattttg
    15121 actagataga ggcaagcgtg catctactaa aatcgtcaca aaatcaacaa attttaaatt
    15181 ttcctgcacc tgtcgacgcg ctttagacat gtgaccagga aaccattgaa tagtagccat
    15241 tgagtttttt cctttcgtag caaggattta gatcccctat tttattttac tatagtttga
    15301 acatagagag ttttcaaatg aatgatgtcc aaacagttct tgttttatga catagaaatc
    15361 tactttatat tatatcatgc cttctttatt ttgtccgatg atagcctttt accctatctt
    15421 ttagcctatc ttttacccta tatagaaaaa agccatcaaa tgatgacttt tcagagggag
    15481 caaaaaactg ttccttctat attctaaaca tttaaatgtc ttctttaaac agtttattaa
    15541 agaaaccgtc tgtgttttta agaagggctt tgaagacctt agatttaaga gcaacagtgt
    15601 gagagaagtc atctggtttc ttcaaatctt cttcaactgc tttatcaaat aaaggcctta
    15661 actcatcata gttactgata tggacgccat caatatcgat agcctcaaaa cctttcttag
    15721 ctttagcaag aacttccccg taccaatgtc tcttccactc ttcaagagta ttaaagtttc
    15781 ctttcgatac tttattaatt attagcttat cgcttagtaa accgtggttg tttttatctg
    15841 cttctgcttt gtatttattt gatacataac taataaagcc attttcataa ccataatagc
    15901 cccacatacg gaaagcattg tgcttaaatg ataatgaacc aggagcacct tgactcgtat
    15961 tcccaccgta aattcctgcc atcatattga catttacgta agctgagttt ggtgtaaaat
    16021 cttctggtct ataacgtcca ttacctggat ttccatgttt tgtcatgaag ttattatcca
    16081 ctaaatcatt gacgctagat aaagtcatta ccttttcttc atctttcaaa tcacggatac
    16141 tatcccattg gtttggacct aaaagatcat tatactgaat cttagagcgc atttctttgt
    16201 caatcttctt gaaccactta ctattgtctc ctttaatttt aggaagtaca gcatcagctt
    16261 ctacatgatc aagcaacatc atagcttcat tgtagtttct catgtagcgg tcaatgtcat
    16321 cacgtgtctt taatttgtca ggatctgggt tgtaccattg gttaccatca tttggacgat
    16381 ggtaagccat gttaattcca agtgcgccgt attcaccatt agtcgttgag ctgtcaggtg
    16441 tttgcaacat accttgagca taggcttcaa cgtctgtacc ttgacgatgc ttatgaccac
    16501 cgaagtaaag cattctatcg tttacgtgtg ttgtttcgtg agtaaaggct gaaataccaa
    16561 atgggctaat catatccgtc accataaaca agaccttgtc atcattattt ggattaggga
    16621 atattgatgc catagcgccc atacgccagt ctctatcatg gtgtcgccat gttggaccat
    16681 ataattcacg aattggagct atagggttac ctttactgtc aaatcctcga cgacctacag
    16741 gagaaccatt gtaggtctgg ttatcccaaa ctggtgtcgg taccatattt tgactcttaa
    16801 gaagtctatc acgaacatta ggcagagcta atctggacca gaaatctaaa taagtttgtt
    16861 gagcatgtgc aacttcatca atcttagttt tgaactcatt acgagcttct tctgtatgtt
    16921 ttccatattt ctcaaatgaa ctgtacgcca tcgtgttata tgttgaaatt aagaacatat
    16981 gggcatcttt aagcgttaga agtggtaaaa tcatacgacc atgaacaccg ttatctaaac
    17041 catcgaacac acgatgacgt ttatctttca actctgtatt tgttgtctta ggttctgaaa
    17101 cataaacatt cttagctgag tggataaacc aatcattgat gtctttatcc tctgtaaaca
    17161 gacgcatgtt gtattctaag aagttacgca aattactttt accagtatta cctgcgatga
    17221 tttcacggta agcatcctga gtccgatccc ctttcaagtt cttttcactt gaaccgatgt
    17281 tgatgagtct gtcaataaca cttggtgttt taccataaaa atcaggtttg aacatcatga
    17341 tgttttttat acttatgtca ccgtatttga tatcatagta acgattgaga taagtcagag
    17401 ccatcatgat tttagcttta ttggtttcca ctttcttgag aagtgatttt atcgcagctt
    17461 catcaccatt caattgatgg tcttcatttt cgaccaagga tttgactaac ttatctagat
    17521 tttgcttcac ttcggcaaag ctttcttcta agtatagatc tttaatataa ccattcttac
    17581 gttcatccgt attctctgca ggtttatcac gtctactcat taaatctctt acttcttgtg
    17641 aaatcaattc cacacttgat aattgagatt taacatcagc aatcaattta tcacgatttt
    17701 taacaaccat attcggtgta taaacaacat caccaagacc agatacacta tattcacgca
    17761 cttgttggac tttagaatca gtattcttag taacatccat ttcttcctta gtaccatcag
    17821 catagtgaac cataatctta tcaatatctg ataaatcggt cacgaattga ccatccttca
    17881 tccccgtaac agaaaggact tctttcttag ctaagtttga atcttctgca agtttgttac
    17941 cttggttgac aatccattct ttattataaa atggttgaag tttctcaata ttacgataag
    18001 ctaaatcacg ttcggatttg tagtcttgag ttgacttata ttcatcttct cttctggtta
    18061 aacgatttaa gcgattgacc acaggttcgt tgatttcgta tttatcagca gtaagtccaa
    18121 aatttgcaat tctcttatta gcttcatctt gactaatttc tttaattttg tcacgagaac
    18181 gtttgtatga atgcttacct gaactgacac ctttgacaac aaagttacgc tctaaccagc
    18241 catttgtgaa ataaccacca tcgtagtcca aatcggaaga accaaagaac tcttcaccat
    18301 tttcaactct catcattgaa atattatctt caagtttacc aaaaggaaga ttgctattga
    18361 taaatccacc tgtttcaaac aaaactttag tcttaatggt tcctttggtg actgatttac
    18421 gaattgaacc gtatttacca attcccatag agtcgttacc attatctgtt ttagcaacta
    18481 aaccacctat acgggctctg ttagcaacaa tatcagcctc gacatatgct tttgcaagat
    18541 tacctctcca aatctcaccg gcaatgccag ccatatattg acctttatca ccaacacctg
    18601 taagattacc gatgaaggct acatttgtca actgaccacc actatcgatt ttattgacga
    18661 tacccgcaat attgttatta gcaactacat taccagttac cttaacatct tcaacagttg
    18721 catttttcac catattggca acaggtgcta ttccgtcagc ccaaggcata ttgatatcca
    18781 tattacctaa attaatattt ttcacagaac cattttcaac acggtcaaat aagggacggg
    18841 caatgttatg aattgtatat tgtttaccat caacacttga tagatgtccc ttaaacgtac
    18901 ctggaacata ttgtttgtta ggtgttggta cattcgttgc attcaaatct gctccgattt
    18961 taaatgtacc atttttatca gcattcatgg catctactaa ctctttaaag ttataataaa
    19021 cgtcatcaac ttttggaact ggtttttcaa tataatgaac atacttgtta cgaaccttcg
    19081 ttgggtctgt atgttgaatc aaatcttgag cttcggcagt gattttataa agtttcttac
    19141 cttcttcagt cacttcttca attttatcaa ctgctaaacg tgttacttta ttatcacgac
    19201 tagtaatttt taagtacatt ttcttcacat cttcatctga aggtttttca gtcataaaat
    19261 cactaggtgt ttcagtacca tcgtcattta ccttcactaa attagtagat gcgatatttt
    19321 taatttcaac ttttttcaaa tccaagcgaa gtggtttctc ttctaatgtt gcagtttctt
    19381 ctcccttgcc acggtcatag gtcatagtgg tctctatctt atagtccttg tagaatttta
    19441 aatcttctac ctgcttatct aattgctctg aagtcaaatc tactgttttg acaatttcat
    19501 ttccatcttt aattgtcgca gtaattttat tgattgtgac tccatctgta ttaactaaat
    19561 gataagaaag agttgcggat cggtttaata catttgtatt tgttctatct aaggtcaaaa
    19621 caggagccgt tttttcttta ggtttttctt tggtaccttt tacaagaatt ttaggcttca
    19681 tttctttcaa aatagttact gtttcaactg ggtcactgat ttttttgcca tgtaactctt
    19741 catagctagt aacaatttga cgttcgccat cctcaccaac ttgtctaaca gaatcatcgc
    19801 ctataaattt gctaggatca gattcttcta tagtggtttt aggaatagtc tctgtccgaa
    19861 tatcggtatg taaagaaggc aactcttctc tttctgatgc aacttctgaa actgtagata
    19921 ttggttcagt atactctgga atgtcgctaa caggtggctc aatcaagttt ccattttcat
    19981 ccactcctgt tgtacctact ggctcagtat attctgggat gtcgttaaca ggtggttcaa
    20041 tcaagtttcc attttcatct actcctgttg tccctactgg ttcagtgtat gctagtttct
    20101 catgaacttc aggctcaaca aggtttgcac ctattggttg cgtatagtca ggcttctcat
    20161 gaacttccgg ttcgcctttc tctgttacaa ctttgggttg ctcaactggc gaaacagttg
    20221 atgctggaga aaccgacgaa acagttttat catcaagctc caagtaacca acatatctgt
    20281 aaccagaaat ttgcaacaca ccatcacgtc cagactcatg gatgttagca ttcaaattaa
    20341 gtgctgaagc agttgatagt gtaactaaac ctgtcgcccc tacaatcaaa aatgtagcta
    20401 tttttttatt tctattatct tttgtgataa tcacaataag actcccgata gctaacaaac
    20461 ccaatgcagt cataatagat tgagaacttc ctgtgtttgg tagtgcgtct ttttcataat
    20521 ccaaagcata tgactctttg gattcatcag gtctaccttg tttgagttga tcacgttcag
    20581 tttgtgtcaa actactataa tctaagtaat gataagtcga tgcaccaaca actgacggtg
    20641 caaataaaag actccccaag aataccgaac caacaatacc ctttattttc cgaatggaaa
    20701 atttatcttt ttttaataat gacaattcta atcctccacc ttcacttttt atttcctaat
    20761 agtaaacact attttttatt ctcaaaaatt gaacttctaa aatcaccggt ttggtcaaga
    20821 taagctttaa agattgcttt tttcagttta agaactctac tatttgtctc aggatataat
    20881 ttggcaactt catcctcagc atcaaatttt actgcatctt caatcatttt ttcaagtcta
    20941 ttaatattat caatagtcac tttctgttgt cgagcccaag aaccgtttgg atcgataaaa
    21001 ctaactttat ttaactttcc aaatttatct tctctttctt tatacatatc tttcttgaaa
    21061 tctatccaag aattatactg gttattaaat acttttgaaa gaacaatttc atcagtaact
    21121 aaacctattt gtttaccata tgatgtaata acttttcctt gagctttcgc ttctttttca
    21181 tactgattag aaatatatgg aaccataccg tctttgtacc ccttggctgc caataactca
    21241 aatgcaatac gtcgtcccat taaatctcct ggtgttccta ttttactgct caatgctgaa
    21301 taaattggtg agaatagatt aattgtatag tagccattcc gcttataagt tgcttcatct
    21361 acataacctc ttcttgttat aatatcatgt tctatcaaac tgttaaatgt agttaattta
    21421 gtaagttctt ctggttttaa tctacgtaca acattcgttg cataaacaga atttccatca
    21481 ggatcaggtt tatattcatt ttctattttt cttaataaat catatttttg atttgtatct
    21541 aatttagcta cagctttacc ttctagtatt tcaagcatgt atattacatc aaacatatta
    21601 tgcatatact tatttagatc atcaacactt ccaaatcgtt gagttggatc tgctacttga
    21661 agccttgttg attcttctga ttgatcatat tttaatatgg aattaatagt gactgttgga
    21721 tcattaggat gatcaggagc ttgtagcagt cctttagcat aaaactctgg tccaagtcca
    21781 tttcgtcttc catagcctcc aagataaatt tctctatctg agttatgtgt catttcgtgt
    21841 gtataagtta ccgcaccatc tttatcaagc atgcgatatg ccatataata gaatgcatcc
    21901 cctgtagcat atgctccatt agaattatga acaacattat ttcccgctgg accgaagaaa
    21961 tgttttatag ctggatgatt agtttcaaaa gttgcttgat atgtatcttt atcttctttt
    22021 tcatctgtac caaatctaaa tgcatcatag actagaacac ttctatataa tttttcttta
    22081 tttttatcat ctagtattct ataccaataa tcatagtgat ctctaaatct aacagccgct
    22141 tctttagctt ttttctcaac atagtcattt aaatcagttc ctgctggatg ttctttactt
    22201 ctatatctat cataagcacc gaaacctata gtcgaaatgt tggctataat aaacaccgat
    22261 ttttcaggta atgttaatag cggcaacacc atacttggat atttccaaga tgggctagtt
    22321 aatctatcat atactccaat tgaatatgga ctaccagcta ttgattgctt atcacttacc
    22381 tctttaatag tagatttttc ttctacaata tatgctttag tttgttcttt aaaccactca
    22441 ttatttgttt tatctggtac aaatgctttt ctatatttct ctaatgcatc aaataaatta
    22501 ttagtcttat aatttttcgc taataaaaca ttataagtta taacattatt ttttgctagt
    22561 aagttattat atcccgattt acctagttcg ataacattat ctaacgctga actatttgat
    22621 ttaccgaaga aatccaagtg gtacatgact aaatctttcg cttttgtatc acgatatttg
    22681 aagtcgtacc aacgctctaa gtatgttaat cctagaagta aagcttcttt attattttta
    22741 attttctcga ttacataatt atctattacc ttattgttat tttcagctat tgcagcatct
    22801 gcagtaagaa gttttgtcaa actatctttc aaattagttt ttgtggtatt gaattgttct
    22861 tctaaatata actccgttaa actaacatcc ttagaaacat ctaatacttt tctaattgcc
    22921 tctgatttat attctacact atttaatgct ggtaatactt catctaaaat attttgataa
    22981 ttgcgaagta atgtattcgg tgtataaatt aagtttgtac cgcctattct atactctgct
    23041 acatttgaaa aatcagtttg ataatttaca ttaagtgtct ctgatgtatt atccgcgtaa
    23101 tatagtaata gtttatttat acttgattta tttttgttaa tatcactaat tacttcttta
    23161 tctttcatag ggactactga caataattct ttattataaa gattactact tgtctctact
    23221 aaatttccgt acttaacaat tgtttctcta ttataaaacg gtaatagttt ttcaatattt
    23281 ttatatactt tttcttttga tgaatcagca ttctcaagat ttttatagtc agttacatat
    23341 ctagaagaga aattaaaatc ttctgtttta atagtatttt tagatacaaa agtagctttt
    23401 ttctctttta tttgtgcatc ttctaatact tctcctcttt gaacagtaga atccttagtt
    23461 aagatttcat catcttcttg tactacgttc acaaccttat tatttttatt actgtatgtg
    23521 ccatttgctt ttataccatt aaaattataa cctgcaatag cattaccatt cgttacatta
    23581 acatcgctta gtacattaga aagtcgaccg gatttttcta atcctccaac cggatcccaa
    23641 agattaccaa ctactccacc aacgtttgca aaacgttgaa cattatttag atttccttca
    23701 gcataactat tactaataag cgcactattt tctactgcac caactattcc accaatagac
    23761 tggtctcctt gtgttgcatt tgaagataaa tcgattgatg cgaacgactt atctattaat
    23821 cccctcggac cagaaagttt gcctactaaa cctccgattt gataactagc aactgtttta
    23881 tatgtattag ttattctacc tgtatagcta ctgttagaaa tagtagaatt attaacttgt
    23941 gatactaatc ctcctatgct acgttcccca gctatcgctc catcagcatg aacgttatca
    24001 atatgagtat tgttatttgc ttctttcgca agtgttgcag tatcgtcctt tgcggaaata
    24061 ttaacatctt ttagtgaaag tttttctact gtagcaccat ttaattcccc aaataatggt
    24121 tttttcaaat tataaatagc ataatatttc tcattatttg ttcctactaa tattccatgg
    24181 aatacattat tcacataact ttcttgacca tctggaagtt caacttcacg agcatccata
    24241 gttgctccta aacggaatgt gccattagga ttgctattca ttgcatctac taaattttta
    24301 aatgatgtat ataccccagt ttcactttgc tgagtttttg gtaaatagta tgtataattt
    24361 tctagtacat tattattttc atgttgtatc agactatttg cacttgctac tatcttataa
    24421 acatctctat tatctttagt atcattagta atgcttgtaa ctggtagcat cacatcttta
    24481 aagttctctg atttaacttt cataaagtaa ttttctgcat tacttggtaa agaagcaagt
    24541 gaagttacat gtcgatactt attaccatct tttgaatata gttctacaga agatatattt
    24601 ctaagttcta atttcttaat aacttctttt tcatctttag cgtcatcttt tttctcatct
    24661 ttatgacgat aaagttcatc gtatactggt ggaatttcat tacctgctat aatactctta
    24721 atccaagcta attgtgtagg agataaaatc aatccgcctg agcgattttg tgctccattt
    24781 tgatgcacac caataacttc accattagca ttaaatattc ctccaccact cataccagga
    24841 tttccacctt gatattgaac accgtaggtg ttattcgcat attcttgttc catttctacc
    24901 gtagcatctt ttaagtgcgt atatttccca gctggatatc catgaacatt tagtttgtca
    24961 ttaagattta ctttcgaata atttttaact aattctacat gttctctgcc agttgtttca
    25021 ggtagcttaa tcactgctaa atcatagata aatccttttg gataatcttt tttattataa
    25081 aaatgaatat tgttagcagt aaatgttcct ttttgtccat caggagtcac ccactcatat
    25141 acgtttttag atttatcacc tctaaattcg ccagtagtat tatcagtaga attattaatg
    25201 aaattatgtg ctactgttaa aagtacattt ggtgcaataa aagtagctga tcctactcca
    25261 gtaaccttcg acgaatctgt aataaagttc atattaatta atgcactaga ttttttctga
    25321 atactcattt cttctggtgt attagtattt tcattatttg gtttagtatc ttctgcacta
    25381 ggttgttcga ttttaccagt atattctttc agtgcttcta ctttctctgg ctcgactatc
    25441 gctccggctt gcacccctgt gtattctggt agtggtgcta tctgctctgg ttcaacaata
    25501 gcgccagcct gcacccctgt gtattctttt gatggttcta ctttttctgg ttctactatt
    25561 gctccggctt gcactcctgt gtattccttc ggtgcttcta ccttctctgg ttcgactatc
    25621 gctccagcct gcactcctgt gtattccttc ggtgcttcta ctttctctgg ctcgactatc
    25681 gctccggctt gcacccctgt gtattctggt agtggtgcta cctgctctgg ttcaacaata
    25741 gcgccagctt gtactccagc atattccggt tcaacttttt caggttcaac aatagctcca
    25801 gcttgtactc ctgtatattc tggtagcggt tctacctgct ctggatcacc cttgtcagtc
    25861 atgactgcct ctggtaacgc tggttgaact tctggtacgc ctttatcact tactacagct
    25921 tctggcaact ctggttggac tgctgactca cctttgtcgg ttaatacagc tgctggtagt
    25981 tcaggctgaa ttgcgggttc aacaatagct ccagactgta cttccttatg ttctgcacca
    26041 gtctcagctt gttcctttat aacttgagct tttttagtac ctttttcgac tattcttgaa
    26101 acaggcgcag tcgttgaagt tgaaataatt tctcgtgaaa cttcttcatt gtttacagaa
    26161 aatattctga cgatttcaac tttcttacct aatgcacctt cttgttttac tcttacagtt
    26221 ccttctgcta aatcaggatt ttcttgaatt tcttcttgaa aatctatttt tgtttctata
    26281 gtttcgtcac gatataagag ttccggtttg ttcaactgac ctgatagcac ttcatcctgt
    26341 ggatttaatg tatttacccc agtcttttcc tttggagaaa tcttctcctc tttcttcgtt
    26401 tctagattct tatgttcggc taattgttct tgagaatctg aagattgttt ctcttctttt
    26461 cttggattga ttaattcagt agagaaaggt ttttcaacta cttgaacttc tgtcggctta
    26521 gttgaagaaa caggtgtttg ttcctgaata gcttgtactg ttgatggatg gtctacaaaa
    26581 tttggtgtaa cattataatc caccttttgt tgttttgtag gagtggctgc tgatttttct
    26641 tgattactta cttcaaaatc agaagtcgtt tttccctctt tgatatatcc aatataagtg
    26701 taacctgaaa tctctttagg aagaggtaat ttttctccag aggtcaattc atagtccgta
    26761 ttgtaattta gcaaaagatg attttctaaa gcatggactg aaactaagac accatttccc
    26821 attcccgcaa ccaatactaa atgtaatacc gttttattct taaccttttt cttggaaaca
    26881 gcaaaaatta aaattcccag agcagctaag ctagcaccag caactagggc ttgcctctca
    26941 ttcttgcttc cagtatttgg taattccgcc agttgatttt gagaatttaa cttataaaca
    27001 agataataag tttcatcatc attctccacg tatgtcggaa tatcatagac aagctgcttc
    27061 ttttcttctg atgatagctc tgaatctgcc acatatttat agtgaactcc cgcagtttct
    27121 tgagcatcca cagatgaact agctaataca gacataaaaa ataaacttga aatcgttgca
    27181 gatacaagtc ctactgataa ttttctaaat gaaaaacgct cttgtttttc accaaaatac
    27241 ttttccatta ttcctccttg aaataaaatt tatatatgtt acaaagacct ttattatatt
    27301 agtgtattat ctattatcta tagaaaaggc agtatacctt aattatactc ttaatttaca
    27361 aaaaagtctt aaaattgaga tgcgctttca tactttgttt tatattattt gggggtacaa
    27421 taacacctac catgaaattt acacggtagg tgttactcat atcactaatc gttctaaaaa
    27481 tggtttgagg cagttgagga gaattccttc tatccagctt ccttgtgctg atgagcgatg
    27541 gtcttcctgc aggctttttt ttagaaaatc tcggacttgt tctggtgcga tttcaaattc
    27601 aaaggctttc attttataga aaaagtcgat gagatgatcg gacaggtatt cagttgaaaa
    27661 gggtacttca ccactttttc gatattctaa taagagccta gaaaatcgag ctttttcttc
    27721 aggaagctca cgaaaatagg aattgaggag ccaagtctgc ttctgttttc tttcaattgg
    27781 atcctgactg gcaattcgtt ggtctttttc cagctctttt tggtattgtt tggccttgat
    27841 agcccgttct gctctatttt taccaaaaag aattttttcc cacttgcgtt cttcttgagt
    27901 cagggtctct gtaaagccaa agtaatcttg ataagcacgc tctgcgggtc ccatggctag
    27961 aaccagattg tctgcatatt gcttggcgat tttatccctc ttcttgcgtt ctttctctgc
    28021 ctggatacgg agttcttgtt cgtagtcaat tttctccttg cctagcttga caaggtagag
    28081 ttggtcatcc gatttcccaa gtaaaaaggg tttgatacac ttttcaagga cttcttccat
    28141 ccgagccttt ttctttggtt ccgccttggt ccaacttcct ccctgaaaga cttctagtaa
    28201 aagctggtag tctctctcag gcgcaaattg attgccacga ttgggtttga aaacaccttt
    28261 ttcccagagc cattttagaa gtcgctcgtc aaagtcactt ttattgacct tgattttttc
    28321 ctttttctga gcttttctgg ttagattttc aacctttctg agcagttttt cttcctcttc
    28381 caattgctgg tcaagggaca atcgatgaaa atgacgaaca cagtcgctac caattggaaa
    28441 gaggcgttgg cctgtgacac cgttaaagag ttcataagcg tatttgatgg catttccaca
    28501 gacacaattg ctacggccga taccgttaaa aatcaaggaa acttcattcc attccttggt
    28561 agcttgttcc caagtatccg ctttcgaagc ctgtaaaact gcatcgtgca gggattttct
    28621 aactggaagt gtcatgaggt ctcctttcta atactcaata aaaatcaaag agcaaactag
    28681 aaagctagcc gcaatcagct caaaacactg ttttgaggtt gtagatagaa ctgacgaagt
    28741 cagctcaaaa cactgttttg aggttgtgga tagaactgac gaagtcagta accatatata
    28801 cagcaaggcg aagctgacgt ggtttgaaga gattttcaaa gagtataagt tatactttta
    28861 caacttgaac ctcgtcttta ccgagtaaaa tcaagtattt ttcaatattt tcaatcgaat
    28921 aggctcgtga taaagcctct tcgtatagag ctaactgacc acgatagcgg tctacgagtt
    28981 gacttggttc atcatagcgg tctgtcttgt agtcgaacag aacaattttg ttttcgtaaa
    29041 gcagatagcc atcaaggata ccacggacaa caaagtcttc ctgactcttt tggtctcgtt
    29101 tgagcatgga gaaaggttgc tcgcgataga gatggtcggt attagcaaga atttcctgac
    29161 cgagtactgt gtcaaagaaa gcaagaattt tatcaagatt gatcttgtct ctgacagctt
    29221 ggctagtttg aacttgtttg agtgtttctg ttaggctagc aagggttagt tgctggctga
    29281 ggtcaattct ctgcatgagt tcgtgagtag cactaccaat ctcagctcca gttacctttt
    29341 ctttggttga aaaatctggc aaatcgaagc tgattttctt gcctactgac tgaccttgac
    29401 cagcaatctc gacaccttcc atatccataa ctggttcgta gaatttcttg atttgacttg
    29461 gggtttgaac actaggaagt tcaatagctg cgcggtgaag agtattataa acttccacct
    29521 ccttcagcat ttccagagct tctttgatgg tatctgactg acgattgtct gcttgggagc
    29581 tatcttggag aggactcttg gtttccaact ctccgatagc ttctctggtc aactgatctt
    29641 cgccaataaa acgataacta aagttgagct tgtccttagt aaacacttta ctgatagccc
    29701 aaagccaatc ttggaaattc cgtgcttgca gtctagtatt gctatttagt ttcccatttt
    29761 tggctgctgg gtattgcttg acttccagct tttcacgaga acccttgccg acaagataga
    29821 gctttttctc agcccgcgtc atagcaacat acagcaaacg catctgctca gaatagcttg
    29881 ctagctgtaa ttcctcttcg ttctgcctat aggtcagact aggaatggag agtttgatgg
    29941 ttttaggata gtggtcttct actgcccctg tctccatctt ggcaatatat ttgacaccaa
    30001 gaccattctg acgactgaga atgacttctg acatagagtc ttgcttgttg aaatcttgat
    30061 ccatattgag gataaagacg taaggaaact ccagcccttt actcttgtgg atggtcatga
    30121 gctctactgc atcttttggc ggtgcgacgg ccacgcttgc caaatcgtgc tgggcttcta
    30181 agacttggtc aatcatacga ataaaacgcg acaaaccttt gaaattgctc ttttcaaatt
    30241 gatcagcacg cagtgctagg gcatagagat tggcctgcct agcaggacca ttcggcaaag
    30301 ccccaacata gtcataataa aaacggtcgt tgtaaatctt ccaaatcaag tcatagagag
    30361 agtgggtttt ggcatacaag cgccaagaag ctaggatatc catgaattgc tttagttttt
    30421 cagctagagc tgtgtgaatc aagccttttt gactacttgc cattttttgt gcattgacca
    30481 gtttctcata gagattttcg tggactttat cctctgcttt ctgaagggac aaacgtgcta
    30541 gctcatcctc atcaaaacca aacattggag acttcataag ggcaaccaag gcatagtctt
    30601 gcaggggatt gtgaatgaca cgaatagtgt ctagcatgac ttgcacttct agggattgga
    30661 gataattgtt ttgctctccg tcagttttga caggaatccc gtactcagac agggcgagga
    30721 gaatctggtc attacgactg cggctggagg tcagaagggc aatttcctta aaggcaacac
    30781 ctttttcttg atgaagtttc agaatctcct tgataactaa gcgcatttcg cctgttagtt
    30841 tcgtttctgt ttgactctct tcttcctcac ctgtatcgtc cttgtcgtag aggagaaatt
    30901 ctgccttgtt gtctggattg ggagtcagtt tggtattggc aaaaacaagc tggtgcttgt
    30961 tatcatagtt gatttcgccg acctcttggt ccatgagacg ttcaaagaca tcattggttg
    31021 ctgacagcac ttctgaacta ctacggaaat tttccttgag gagaatgagc ttgccttctt
    31081 ggggattttg cgcatagcgt tggaatttct cattgaaaat ctgcgggtct gcctgacgga
    31141 aacgatagat ggattgcttg atatctccca ccataaagcg attgtggcca ttagacaaca
    31201 attccagcat ccgttcttga atatggttgg tatcctgata ctcatcgacc atgacttcat
    31261 ggaagcgctc ctgataagac tcacgaactt gtgggaaatt ttctaaaatc tcaatggtgt
    31321 aatggctgat atcagcgaat tcaaaggcat tttcctgtcg ttttctctga cgataagcct
    31381 ctacaaaatc gctcatgaaa gattggaagg ttttagctag tttccaagtg tctccatgat
    31441 aacgttcttg atagtcgaga atcgctatct ggtctgataa ttgtcctagt ttagtaaact
    31501 gggtctttct ctcttcgttg taggcatcag ccaggggctt caaatcagcc ttacggctgg
    31561 cattagtcag agcacgaccg tttttctcct tagagatggc gacaacacgc gcaagtactg
    31621 cctgataagc ctgactatcg aactcctgat ttagggagcc aatttcatcc agaattaact
    31681 gaacattttc taaataggca gcctttgcaa actccttggc atcgttatcc agatggtaac
    31741 ggaaaaagct ttccaaatcc cagagggctt gtttgatttg ctcagtcagt ttttcttttt
    31801 cactggtaaa atcagctttc tcaaagcctt tgaggaaaga ttcactcagc cacttttgag
    31861 gattactggt ggattggagg aagtcataga ttttatagac ttgctgccgc agaccccgtt
    31921 cgtccttgcc acgcccagca aagtttttca gcaaatgact aaagctctct ttctgtttac
    31981 cttggtaatg cgcttcaaag acctcatgaa agacttcgtt ttcgagaaga agttgctcgc
    32041 tttggttttg taaaatacgg aaattaggtg caatatcaag cagataacca tgtttgccaa
    32101 ggaatttttg tgtgaaagag tccatggttc cgatggcagc gttgggtagg tctgccaact
    32161 ggcgacccaa gtgttgtttg agatcgacat catctgtttc ttggattttc ttgctgattt
    32221 ttttctctaa acgttcttta agttcagttg cagccttgac ggtaaaggtt gagataaaga
    32281 gttgagaaat ttcgacacca cgcgccaatt ggtccagaat gcgctctgcc atgacaaagg
    32341 tctttccaga accagccgat gctgagacca ggatattctg accagaagtg tagatagctt
    32401 cgatttgttc ggcagttttc ttctgttcct tgctcgaatt tgcttctgct tcttgcagtt
    32461 tttgaatctc ctcctcactt aaaaagggaa taagcttcat cgatttaact cctctcttat
    32521 tttttcaaac caagcttgct tgagtttttc tccgaccaga cgcttgccat cagctaggtc
    32581 caatttttct aggaaacggg cttggcccag atggtaattg gcttcaaagc ctgtaatagc
    32641 ctgatgttgc tggacgtatg gggcaatgct tctgccattt tcagtataag gattgatggc
    32701 gaaccggcct gctaaaatct tctcagcagc tttcttgtaa agataggcat tgtagtccag
    32761 taggagctga aattcctcat ctgtcagttg attagccttg tttttgttat aaaattcgcc
    32821 taaataactg ctttcttttt ccaagaagag cccttggtat ttcatagatt tgctggcttc
    32881 taccactgct cctgccagac tttttaccgc catcagagat tggacaggtt cagccatttc
    32941 caagtacatg gcgccgaaaa agttctgctt cccttctctt tttagggcag caagataggt
    33001 tggtaactga gaattgagcc cattaaagaa atgaggaaac tggaactgag tcagactgga
    33061 tttgtagtct actactccta tcgctccatt agctttcaaa cggtcaatcc ggtccacctt
    33121 gcctcgtaca aagacactgc gtccattgtc taattgaata aaggcttggt cttttccacc
    33181 aaaatttgct tcttctttga tggtttcgat ggctggattg tgtcggagaa tatgtccagt
    33241 cgtccgtgca acatcaagca aaacttcctt ggtaaactgg gcttccaaac tttcttgata
    33301 aatagcttca aattcgcgtt cttgactggt ttcttgaata gcttgttcta gacgttggtc
    33361 aaaggaatct tcattaggca actgtaaggc gcgttcaaag atacgatgca agaaattccc
    33421 gtgactacgg gcatcaggac gcaaacgtaa ttcctcctgc aagcctaaaa cgtagcgtag
    33481 gaaataactg tattcattgc gataaaactc tgtcaaaccc gacgtagaca ggtaaaactc
    33541 ctgtttggca ggatagagag cttgcaaggt gtccttggct aaggtcttgc tgcttggact
    33601 ggttgggata gctggatttt ccagaccttg cagatctagt tttttaccta tgacacgcga
    33661 cagaaccttg acaaaagtca aatcttgctc agtatcgctc atctcaccct gctggtgata
    33721 ggcaaccaga ctagacaaaa gactgtgata ggaccccata tcctccttag acagtccttt
    33781 gtgattcatc ctcttctctc tccgcctaaa tccaaaatgg atcaactctt gaagataggc
    33841 agattcctta ctttcacttt cgttaaaaag gcttggagcc gacaagaaca actgcttacg
    33901 agcagaattg accaaggaaa gcatagtgta gcgatttttc ttgagatttt cactgctggc
    33961 aatcagtaat tgaacgcctt cttcggtcgc ttggtttagg ttttgccttt cttcatctgt
    34021 cagaagactg gtgttttgag aaatttttgg taaattgtcc tgagttagtc caatagcata
    34081 gacaaagtca gcagtcaatg gtgcaatcaa atcgtaactc tgcaccagaa cagtgtccac
    34141 tgttgctgga atggtacggt attgggacaa actcattcca gaatggagca aggctaggaa
    34201 gtcttccaga ctaacctgtg aaccagcaaa aacagtcgca aattgttcta aaacatggca
    34261 gaaagccttc caaacttcgg cttgtctttc ctgttctaca gcttccaaag tggttgtcaa
    34321 atcttgtaac tgcttggtca cagctccttc ttttagaaag acactccatt tttgtaggag
    34381 gttttcagcc ttttgttttc ggctggcaaa gagggtttca agaggtgcta aaattctcag
    34441 gcggaggaca ttcaaacgct caagattaaa ttttccatgg tgggatttgg tgaagatttg
    34501 ctgaaaggct ggcaagccat tgataccaag atagcggata tattgctcaa aagcatcaat
    34561 atcagactga ctgaggtcag tatacaaatc agttctaaga agattaatca aatcctcctg
    34621 acgaaaacgg taacgtttta aagctaaaat agactcgaca aactgagtca agggatgatg
    34681 agccatggct tcgcttctac caagataaaa aggaatctga tactggtcaa aaatggtttt
    34741 gagagataac tggtaagaag ctacatcccc caagagaata cgaaaatgct tgtagctcag
    34801 gtctgagttc tcatgtaatt tctgacgaat actacgggct actagctcca actcctcctt
    34861 ttgcgtcaaa caagaccaga tttgtaaatt ttcacggtct ttctcatcga catccaaagc
    34921 gagttctgaa aagtcataag aagactccaa caaacgagag gccttgtcaa aactatccat
    34981 cttctcatga gtttgagaac agtcctgagc aggcgtttgg tatttagaag ccagatgatg
    35041 gagaaatttt acgctggctt ggtagagatt gccctcgcta aaaggactgg tataggcttt
    35101 cttactagca taagccccga taacaatctc aacacctttg ccgtgaagta agtccacaac
    35161 ccgctcttcc tcagcagaaa aacgagtaaa gccgtcaatg accaaggtga tttgattaaa
    35221 atcactactt accttgtcat tctcaatagc ctcaatcaaa tgggacaact gacttccctg
    35281 ggctaactga ccttgattaa gataggctgt tactttctca aaaatcaaga gtaaatccgc
    35341 cctcttatcc tcatctgtta aattctccaa gtccaaaaaa ctcatctggg atttggtcat
    35401 ctcatggtaa agctcaatta actgctggat caattgagga tcctgcttaa tagcgccata
    35461 aacacgcaag tccttgggat cgagttcggc aaggcatttg taaaaggcca acccaagacc
    35521 gatatcatca agagtagttt tagctggtaa atcattcaag accagataac gagccatttg
    35581 agcaaagcgc gtgacggtaa tcgaaaaaga agcctgctgg gacaagcatt ccagcacggc
    35641 gcgttccttt tcaaaagaaa gagagttggg ggcaatgtag aagacccgct tgccagctgc
    35701 aactagctct tctgcctctc ttgttagaat ttctgtcaaa gaagtccgaa tatcagtata
    35761 aagtaatttc atctcagcct cgttggaatt tttcatcacc ctatattata ccatgattag
    35821 cctcgtaaat ctgttaaaat atttaggcca tcctttcttt tcttcatcat ctgctaaatc
    35881 ttaaatactt agctttactt gtattagata gaataagtct ggctactgaa aatcacataa
    35941 taaaaaagcc tcggtaacaa ggctttgagt tttatgattg tttcttaggt acggaataca
    36001 cttcaatgtg ttgtcccagt atcttaatgt cgactggtag attgtctgat ttatcgccat
    36061 caacatcgga ctctaattcg atatcagaag aagttttaat attacgtgcc tttatatatt
    36121 caatattctt gatagaatga ttgaactata gtaaattgaa actataatag tacaccgtgg
    36181 atgctaaaat atttctagaa attaatttga tttccctaat caagctgttc gtatcttatt
    36241 tcaatctact atagtaaaat gaaccaaaaa tagtacacaa tgtggtataa tcttcttatg
    36301 gcatattcaa tagattttcg taaaaaagtt ctctcttatt gtgagcgaac aggtagtata
    36361 acagaagcat cacacgtttt ccaaatctca cgtaatacca tttatggctg gttaaagcta
    36421 aaagagaaaa caggagagct aaatcaccaa gtaaaaggaa caaaaccaag aaaagttgat
    36481 agagatagac ttaaaaacta tcttactgac aatccagacg cttatttgac tgaaatagct
    36541 tctgaatttg gctgtcatcc aactaccatc cactatgcgc tcaaagctat gggctacact
    36601 cgaaaaaaaa gaaccacacc tactatgaac aagacccaga aaaagtagcc ttatttctta
    36661 agaattttaa tagtttaaag cacctagcac aggtctaaca aatgaatggt gagttaatcg
    36721 ctccaatgac ttacgaagag acgatgacga gcgacttttt tgaagcttgg tttcagaaat
    36781 ttctcttacc aacattaacc gcaccattgg ttattatatt aaaacgaagt aagaatagga
    36841 caaatcgatc aggacagtaa aatctaattc taacaatgtt ttagaagtag aggtgtacta
    36901 ttctagtttc aatctactat attaatggac aatgcaagat tccatagaat ggggaagcta
    36961 gaactcttgt gtgaagagtt tgggcataaa cttttacctc ttcctcccta ctcgcctgag
    37021 tacaatctta ttgagaaaac atgggctcat atcaaaaagc acctcaaaag ggtattacca
    37081 agttgcaata ccttttatga ggctcttttg tcttgttctt gtttcaattg actatataaa
    37141 ttgtctaagc gaaacaaccg ataagaattg gcacaaaagc gaccgtattt ttgttaccaa
    37201 tacaggaaaa ccagttcata gttctatctt gagcaagtct ctccagcgag caaacgaacg
    37261 ccttaaaaaa ccaattccca aacatctgtc ccctcacatc ttcagacaca ccactattag
    37321 catcttatca gaaaataaaa ttcctttaaa aacaatcacg gacagggttg gtcattccga
    37381 ctctgaagtc actacttcca tctacaccca cgtcacaaag aacatgaaag atgaagcaat
    37441 caatgtactg gataaagtta tgaaaaagat tttttaaaaa gttttgtccc ttttttgtcc
    37501 tctaaataca aaaatagccc ttcggataaa atccgagggg ctagaaacgt tgttaaatca
    37561 acggccgaac ttttgaattt catggttcgg gataaaatag ttcactgaac tattttattt
    37621 tttaaggttg tagaatgatt tcaatccacg atattcagct acttcaccaa gttggtcttc
    37681 gatacgaagc aattggttgt atttagcgat gcggtctgta cgtgaaagtg aaccagtctt
    37741 gatttgtcct gcgttagttg caactgcaat atcagcgatt gttgaatctt cagtttcacc
    37801 tgaacggtgt gatacaacag cagtgtaacc agcttcttta gccatttcga tagcttcaaa
    37861 agtttcagta agagtaccga tttggttaac tttgataagg attgagttag cagcaccttc
    37921 ttggatacca cgtgcaaggt agtcagtgtt tgttacgaag aagtcgtcac caacaagttg
    37981 tactttctta ccaagacgtt cagtaagagc tttccaacca tcccagtcgt tttcatccat
    38041 accatcttca atagtgatga ttgggtattt gttaaccaat tcttcaaggt agtcgatttg
    38101 ttctgcagat gtacgaacag cagcaccttc accttcaaat ttagtgtagt cgtaaacttt
    38161 acgttcttta tcgtagaatt ctgatgaagc acagtcaaat ccgataaata cgtctttacc
    38221 tggtacatat ccagcagctt caatcgcagc aaggatagtt tcaacaccat cttcagttcc
    38281 ttcgaaacga ggagcgaatc caccttcgtc acctacggca gtttccaaac cacgtgattt
    38341 aaggattttc ttaagagcgt ggaagatttc agcaccgtaa cgaagggctt ctttaaatgt
    38401 tggcgcacca actggcaaga tcatgaactc ttggaaagcg attggagcgt cagagtgaga
    38461 accaccgttg atgatgttca tcattggagt tggaagaact ttagtgttga atccaccaag
    38521 gtagctgtaa agtgggattt caaggtagtc agcagcagca cgagctacag cgatagacac
    38581 accgaggatt gcattcgcac ccaatttacc tttgttagga gtaccgtcaa gtgcaatcat
    38641 agcacggtca atagcttgtt gatcacgtac atcgtagcca atgatagctt cagcaatgat
    38701 gttgtttacg ttgtcaacag ctttttgtgt accaagacca ccgtaacgag atttgtcacc
    38761 gtcgcgaagt tcaactgctt cgtgttcacc agtagaagct cctgatggaa ccataccacg
    38821 tccgaaagca cctgattcag tgtaaacttc tacttcaagt gttgggttac cgcgtgagtc
    38881 taggacttcg cgagcgtaaa catcagtaat aattgacatt ttttactctc cttatgagtt
    38941 aaatttttta cacctctata ataccttaaa acccctcctt tttcaagaaa aaacgttatc
    39001 tttgtgcaac ttttccttaa ctttataaag taatcgcttt cttttgtctg ttttattcta
    39061 acttttatga tatactgttt tcatgacaga tttatcaaaa caattacttg aaaaagctca
    39121 tggtgggtta aaaataaatc cggatgagca aagacgctat cttggtactt ttgaggaaag
    39181 agttcttgga tatgtagata ttgacacagc aaatagccct cagttagaaa aaggcttttt
    39241 atttatttta gaaaaccttc aggaaaaagc aaagccacta tttgtgaaga tttcaccaac
    39301 tatcgaattt gataagcaag ttttctactt aaaagaagca aaagaaactg atagtcaagc
    39361 caccatagta tctgaagagc atattacttc tccttttggc ctggttattc atagcaatgc
    39421 accagttcaa gtagaagaaa aagaccttcg acttgctttt ccaaaacttt gggaagttaa
    39481 aaaggaagaa ccagccaaaa catccttatg gaagaaatgg tttagctaaa tcttgcacat
    39541 atttaataag tgcccaatat tggcagccgt gcgctccaga tagagactgg catttttcaa
    39601 actatcttct aaaggttcac ttttctccaa aatagaaaag acagcttgga tattttcaaa
    39661 tggtagggga ggtaaatctt cagcaagact accgcaaata gcaataacag gaactccaac
    39721 aggggttctt tttgcaacac ctataggcgc tttcccagca aagctttgac tatcaagtct
    39781 tccttctcca acaacaacca agtcagcatc tgaaactttc ttatcaaagt tgattaagtc
    39841 caagcaggta tcaattccag acacgatact tgcctgagca aaggcacaca aaccagcagc
    39901 aatccccagt cctccatcat tactggccgt gccaccaaca ccgatataaa tatctttaat
    39961 ccctttagaa atgagatgga gaatcaactc tccaatacca caagtttgga tttgaagtgg
    40021 atttcgtttc tctagcggaa tttttccaag accaaccaag tcagctactt caaatagtgc
    40081 cagttcccct ttttgaaaat agcgcatggc ttctttttgt ccaaaagggt ctgtcacttg
    40141 gatccatttt tcttttaggt caagagaatg tcggatagca tctacagtac cttctccccc
    40201 atcaccaaca gggcagagga gacattctac atctgctatc gattgttgga agcctctttt
    40261 tattgcttca gctacctgtt gagctgtcaa gctttcctta aacgaatccg gtgcaattac
    40321 aatcttcata ttttccctca ttctaaacag tcaatcaaag gaagaacttc taaaaaatcc
    40381 ctcttgtcaa catgatgtgg tatttctttt ttgagcattt ctttggaaca aaaggcgatt
    40441 cctaactccg ccgacttcaa cattaataga ttattaaccc catcaccgat tgccaccgtt
    40501 ctttctttag aaagttttag tttctttctc catttttcca gagtttcttt tttgacctgg
    40561 ggacttataa tttgtccaac taattttcct gttaaaagac cttctttgac ttcgagctgg
    40621 ttggcagtga aataggcaat accaagggat tttgctaatc tctccaacta ttggtgtaaa
    40681 tccaccagac accagaccaa ctaggatgcc attcttttgg agaatagaga tgaactctgg
    40741 gacatttagc gatagatgaa ttgagttgaa gacgttatca aagaccaaaa taggaagacc
    40801 ttccaacaag gacactcttt ttcttaaact gctttcaaag accaactctc ctcgcattgc
    40861 tcgacttgta atctgcgaaa tttccgcctc atgacctgcc tctctcccta aaagatcaat
    40921 cacttcttct aggattaagg ttccatctac atccaaaaca cacaagcctt ttacttgaga
    40981 catcagttct cctctctaaa cagcctaaaa atcgtatgaa gtcatcatac gattttatct
    41041 attaattaac taaactatgg tacaagtcaa ggtatgactt gcaggctgta tcccatgaga
    41101 agtcactctc catagcttgt ttttgtaggt ttctccaaat gtctggatgg tttctataca
    41161 agtccaatgc tgtttggaaa gtccaattta accaataagg agatagattg tcaaagctaa
    41221 agccagtacc gcttccttcg attggattga aagcgcgaac tgtatctcgc aagcctccaa
    41281 cttcatggac caatggcaag gttccataac gcatagccat catttgagac aagccacacg
    41341 gttcaaaacg acttggcatg aggaagaggt cacaagcagc gtagatttcc tgagcaagtt
    41401 tgacatcaaa agtgatattt gctgatagct tgtctgggta aatctgagca aaccatgaga
    41461 aagctccttc aaaggctgga tcgccagttc ccaaaagaac aatctgaaca tcttcttgca
    41521 agatatggtg aagactttcg accaccacat caaaaccttt ttgacgtgtc aaacgagaaa
    41581 caattcccac cagtggaacg tctgctctaa caggcaagcc aactctttct tgcaattttg
    41641 ccttattttt ggctttccca gacaaatctt cctgattgaa atgatagtct aaaagagcat
    41701 ccgtctgagg attataaaga tcagcatcaa tcccattcac gataccagat actttaccag
    41761 actccatttt aagaatctga tccaaattac atccaaactg actagtcata atttcatgag
    41821 catagctagg tgaaacggtt gaaacacggt tcgcatagag aatacctgcc ttcatccagt
    41881 tcagacagtt gttccatcga agggtgccat cagcgtaacg ttcaaggcca actccaaaca
    41941 aatcacccaa cattccttct gaaaattgtc cttggaattc taaattatga atggttaaaa
    42001 ctgtttcaat gtcctcatag gcttgaatcc aacagtattt ttccttcaac aagaaaggaa
    42061 tcatagctgt atggtagtca tgaacatgga gaagatcagg aataaagtca atcctttcca
    42121 tagcctcaat ggcagccagt tggaaaaagg caaagcgttc tccgtcatca aaatcaccgt
    42181 aaacatgacc acggaagaaa taatattgat tgtcaataaa gtagaaggtt acaccattta
    42241 atactgtttt cttaattcca caatactgtc tacgccaacc aacgctcacc tcaaaatgaa
    42301 gcacatcttc aatctgattt ccaaatttag cctctaccat atcatagtag ggtaaaatca
    42361 ctgcaacttc gtgcccagct tttaccagtg attttggaag agcgccaatg acgtctccca
    42421 aaccacctgt ttttgaaaag ggtgcaccct ctgctgctac aaataaaatt ttcatgaatg
    42481 aatatcctct gttactttag cacctttctt aaccacaact ggatgttctg cagttcctcg
    42541 aatcacaaca ccaagctcaa cttcaacccc tttgtccaag atagcatatt cgacctgagc
    42601 cccttctcca ataacaacac gagggaagag caggctatct ttaaccaagc tatccttatg
    42661 gacatgaata ttacgtgata gaacagaatt agctacttga ccttcaataa tactaccaga
    42721 ggcaaactga gaagtgctta ccttagatgt attagcatag taagttggct cttcgttttt
    42781 gacctttgta taaatctttt ggtttggtga gaaaagagaa tagaattttt gtgattcaag
    42841 catatcgata ttcgcttgat aataagattt aacagagtga atattggcta gatagcccgt
    42901 gtactcgtag gcaaaagctc cctcttttac agccaaatcc cgtaaaacat agcgcaattt
    42961 ctctggatgt tcttttttag cttcttcttc caagtgttca atcaaccaag gtgtatcaac
    43021 gacaaagata tctgtagaca tattgaacgt ttcagctgtt gacttgctat caaagagttt
    43081 atgagaaaga acatggtctg tttcatctac atccaagatt gcatttactt ctgaaatatc
    43141 tttcttagct agttttttat aaactacagt gataggctct tttgttgtac tatgtaggtg
    43201 gaaaacttgg ttcaaatcaa tgttaataag aacatcgcag ttgagggcaa ccgtttggtt
    43261 tgagccagaa cgtttcaaat aagtaagaag ctgttggtag tattcttttc caactgtact
    43321 actttctaca cgggtattgt aaattcctag atagtaatgg ctaagaaggg ttgataagcc
    43381 ccactcgcgc cctgaacgaa tatggtcaaa gactgagctg atattatcct gctggaaaat
    43441 accaaagaca ctacgaacac ctgcattagc aaggcttgaa agtgggaagt caatcaaacg
    43501 atatttccca ccaaatggca aacttgctac tggacggtgg tccgtcaatg tcgacatatc
    43561 gtgaaaacca actgtatttc ctaaaatggc agaatattta tcaatcttca tctgttgcta
    43621 cccccactac ttcattatat cctacaactt gtacttcatc tgttccatca atttcgacac
    43681 cgtcagaaat aatcgcacct tcaccaataa tggcacgttt aatcttagct ccttgaccaa
    43741 tgatagctcc actcatgata actgaatcaa ggacttccgc tccttcgcga acttgcgcgc
    43801 ctgttgaaag gatagaatgt ttaacagttc catcaacgaa acatccgtct acaactaatg
    43861 agtcttccac atgagcattt gccccgagga agtttggtgg tgaaatcaag tttcttgagt
    43921 aaatcttcca ttgacggtta cgactatcca aggcattttc tggagaaata tactccatgt
    43981 tcgcttccca aagtgactca atagtaccaa catctttcca ataaccacta aattcataag
    44041 cataaacact ttcacctgac tcaaggtaat ttggaatgac atttttacca aagtctgaca
    44101 tgccaacctt gctcttttca gcagcgacta acatattacg aaggcgttgc caatcaaaaa
    44161 tgtagattcc catagaagct tttgtagatt taggttgagc tggtttttct tcaaattcaa
    44221 caatacgatt gttagcatct gtgttcatga taccaaaacg gcttgcttct ttaagaggga
    44281 cgtctaaaac tgctactgtc aagctggcat tattatcctt atgagactgg agcatatcat
    44341 catagtccat tttgtagatg tgatccccag acaaaatcaa gacatactca ggattgacac
    44401 tgtcgatata gtcgatattt tggtaaatag cgtgactagt cccctcaaac caacgatttc
    44461 cttcacttgc agaataaggt tgaagaatag agacacctga attaataccg tctagtcccc
    44521 agcttgaacc attcccaata tggttgttga gagcaagtgg ttgatactgt gtaacgaccc
    44581 caacattatg aatccctgag ttggcacagt ttgatagggc aaagtcaatg atacggtagc
    44641 gcccaccaaa ttgcacagct ggttttgcga tgctttgagt gagtttaccg agacgagttc
    44701 cttgcccacc agcaagaatc aaagctaaca tttcattttt cattttctac tcctttttgg
    44761 tttttatttg tgacggtttt agtagatttc aagcgacgtt tgattttcca tacacttgct
    44821 cccatagccg gtagggtaaa ggttaaggtc tgctcataat ctttccatag tccttcttgc
    44881 gtttgaacag tttgattatg ttctttccaa acgcctcccc actcttccaa ctcagtattc
    44941 catacttctt cgtaaattcc tgcaacgggt agtccgattg taaaatcttt ccgctcaaca
    45001 ggtaccatgt taaagataca gactaacatt tctccctttt tacccttacg aataaaggaa
    45061 agaacactct ggtctcgatt atccgcatca atgatttcaa taccatcata gctggtatcg
    45121 atttcccaca gacagcgatg atctttgtaa aactggttta gctgagaagt gaaatacttc
    45181 atcttagcat tcattgggtc ttctaggtta gaccattcca actgttcttc agatttccat
    45241 tctaggaatt gaccgtattc gctacccatg aagagcaatt tcttaccagg atgacaaatt
    45301 tggtacgtat agagattgcg caagcctgcg aattgattgt aacgatctcc ccacatctta
    45361 tgcatcatac tcttcttgcc atgaaccact tcatcgtgcg agaatggcaa gagataattc
    45421 tccttgaaaa catacataaa gctgaaagtc accaggttaa agtcatattt acgatagatc
    45481 ggatcttctt cgtagaaacg gaggatatca ttcatccagc ccatgttcca tttgtagtca
    45541 aatcctagac caccaatctc tttcattccc gtaatcttgg tcgcagacga actttcttct
    45601 gcaatcatca tcacatctgg atattctaac ttaataacct cattcaagcg ctgaaggaaa
    45661 taataacctt catagttgag atttccgcca tctttattag gtgtccatgg agcatcatca
    45721 tagtccaaat agagcatgtt gctaacagca tccacacgaa taccatccaa atgatagaca
    45781 tcaatccaat gcttaatgca agaaattaag aaggactgga cttcattttt tccaaggtca
    45841 aaattaaggg caccccaacc atggttatga gccttattat ggtcttggta ttcaaaagtc
    45901 ggtgtcccat cataataggc taaggcatca tcgttgatgg taaagtgacc tggtacccag
    45961 tccacaataa ccccaatatt atgggtatga cactcctcga caaaatcttg aaactcctct
    46021 ggtcggccat aagcatgctc taaagcgaag taacccataa gctgataccc ccaactcaag
    46081 cccaaaggat gggacatcaa gggcataaac tcaatatgag tatagttcat ttcaacgaga
    46141 taaggaatga gttcatcctt gagctgggca aaactataag gactgccatc agaatttctt
    46201 ttccatgatc cagcgtgaac ttcataaata ttgacaggac gctcttcaaa gccccaacgt
    46261 tttcttcgtg ccagccaaag tccatccttc catttcttct cacgaagctc tgttaagatt
    46321 gcccctgttc ctggacgagc ctcatacctg acagcaaaag ggtcaatctt catcagttga
    46381 tgaccatttt gacgtgtgac atgatatttg taaatatgcc cttcttgagc catattggta
    46441 aagacttccc agaccccaaa atcatttctt accattggaa tctgattttc aatccagttg
    46501 gtaaaatcac caaccaagtg aacagcctga gcattaggtg cccaaacacg gaaggtatag
    46561 ccatgctctc catttagttc ttccctatgt gctcctagat aatgttggag ataaaaattt
    46621 tcacccgtca taaaggtttt taatgcttct ctattatcca tatactcctc ttctcctgta
    46681 agcgttttct atgtttttat tatactacct ttttagagaa gattcaagta aattactata
    46741 cttctttaat tattttgaaa atctacaaca agttcactta ctcgttcaat tgtaaatcaa
    46801 tattttttca aaaaattgcg aaaactcctt tctttttcta ctatagtgaa atgaaataaa
    46861 acatgcgcaa atcgattaag gaatttaatc taatttctaa caatgt
//
LOCUS       DAVMJI010000015        45636 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.015, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000015 DAVMJI010000000
VERSION     DAVMJI010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.015"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(1..450)
                     /locus_tag="VYR58_000971"
                     /pseudo
     CDS             complement(1..450)
                     /locus_tag="VYR58_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            445..699
                     /locus_tag="VYR58_000972"
     CDS             445..699
                     /locus_tag="VYR58_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV3622151.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            994..2328
                     /gene="trmFO"
                     /locus_tag="VYR58_000973"
     CDS             994..2328
                     /gene="trmFO"
                     /locus_tag="VYR58_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV3622152.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYIGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2412..3149
                     /locus_tag="VYR58_000974"
     CDS             2412..3149
                     /locus_tag="VYR58_000974"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV3622153.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            3158..3715
                     /gene="frr"
                     /locus_tag="VYR58_000975"
     CDS             3158..3715
                     /gene="frr"
                     /locus_tag="VYR58_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV3622154.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAIKHIDDMTANKEKELLEV"
     gene            3775..4629
                     /gene="cvfB"
                     /locus_tag="VYR58_000976"
     CDS             3775..4629
                     /gene="cvfB"
                     /locus_tag="VYR58_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV3622155.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPVLKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4638..4853
                     /locus_tag="VYR58_000977"
     CDS             4638..4853
                     /locus_tag="VYR58_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV3622156.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4939..5907
                     /locus_tag="VYR58_000978"
     CDS             4939..5907
                     /locus_tag="VYR58_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV3622157.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(5885..6064)
                     /locus_tag="VYR58_000979"
     CDS             complement(5885..6064)
                     /locus_tag="VYR58_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622158.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            6100..6601
                     /locus_tag="VYR58_000980"
                     /pseudo
     CDS             6100..6601
                     /locus_tag="VYR58_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            6604..6863
                     /locus_tag="VYR58_000981"
                     /pseudo
     CDS             6604..6863
                     /locus_tag="VYR58_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(7230..7556)
                     /locus_tag="VYR58_000982"
     CDS             complement(7230..7556)
                     /locus_tag="VYR58_000982"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622159.1"
                     /translation="MVDIAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(7502..7915)
                     /locus_tag="VYR58_000983"
     CDS             complement(7502..7915)
                     /locus_tag="VYR58_000983"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV3622160.1"
                     /translation="MGAHFLTKQAGGSGVLLGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLMSNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(7916..8341)
                     /locus_tag="VYR58_000984"
     CDS             complement(7916..8341)
                     /locus_tag="VYR58_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV3622161.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            8518..9087
                     /locus_tag="VYR58_000985"
     CDS             8518..9087
                     /locus_tag="VYR58_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622162.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKDRIVTRVHYVLTKEDYFANK"
     gene            9155..9805
                     /locus_tag="VYR58_000986"
     CDS             9155..9805
                     /locus_tag="VYR58_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV3622163.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVKKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            9789..12029
                     /locus_tag="VYR58_000987"
     CDS             9789..12029
                     /locus_tag="VYR58_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV3622164.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGIFGFWFVFQNWQQSQASQNLADSVEGVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            12208..12396
                     /locus_tag="VYR58_000988"
     CDS             12208..12396
                     /locus_tag="VYR58_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622165.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYARYEVINYYSGGY"
     gene            12429..13016
                     /locus_tag="VYR58_000989"
     CDS             12429..13016
                     /locus_tag="VYR58_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622166.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            13020..14204
                     /locus_tag="VYR58_000990"
     CDS             13020..14204
                     /locus_tag="VYR58_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622167.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASPGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKEFFN
                     RF"
     misc_feature    14368..14499
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14515..15045
                     /gene="infC"
                     /locus_tag="VYR58_000991"
     CDS             14515..15045
                     /gene="infC"
                     /locus_tag="VYR58_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV3622168.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            15078..15278
                     /gene="rpmI"
                     /locus_tag="VYR58_000992"
     CDS             15078..15278
                     /gene="rpmI"
                     /locus_tag="VYR58_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV3622169.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15330..15689
                     /gene="rplT"
                     /locus_tag="VYR58_000993"
     CDS             15330..15689
                     /gene="rplT"
                     /locus_tag="VYR58_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV3622170.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15747..16127
                     /locus_tag="VYR58_000994"
     CDS             15747..16127
                     /locus_tag="VYR58_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV3622171.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16377..17177
                     /locus_tag="VYR58_000995"
     CDS             16377..17177
                     /locus_tag="VYR58_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV3622172.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            17140..18126
                     /locus_tag="VYR58_000996"
     CDS             17140..18126
                     /locus_tag="VYR58_000996"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV3622173.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            18168..20201
                     /locus_tag="VYR58_000997"
     CDS             18168..20201
                     /locus_tag="VYR58_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEV3622174.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKTTNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(20262..21917)
                     /gene="pavA"
                     /locus_tag="VYR58_000998"
     CDS             complement(20262..21917)
                     /gene="pavA"
                     /locus_tag="VYR58_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV3622175.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            22022..22519
                     /gene="ybeY"
                     /locus_tag="VYR58_000999"
     CDS             22022..22519
                     /gene="ybeY"
                     /locus_tag="VYR58_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV3622176.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22500..22895
                     /locus_tag="VYR58_001000"
     CDS             22500..22895
                     /locus_tag="VYR58_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV3622177.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22912..23811
                     /gene="era"
                     /locus_tag="VYR58_001001"
     CDS             22912..23811
                     /gene="era"
                     /locus_tag="VYR58_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV3622178.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23859..24683
                     /gene="mutM"
                     /locus_tag="VYR58_001002"
     CDS             23859..24683
                     /gene="mutM"
                     /locus_tag="VYR58_001002"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV3622179.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24683..25288
                     /locus_tag="VYR58_001003"
     CDS             24683..25288
                     /locus_tag="VYR58_001003"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV3622180.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEAIVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            25275..26474
                     /locus_tag="VYR58_001004"
     CDS             25275..26474
                     /locus_tag="VYR58_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV3622181.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRIFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26474..26623
                     /gene="rpmG"
                     /locus_tag="VYR58_001005"
     CDS             26474..26623
                     /gene="rpmG"
                     /locus_tag="VYR58_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV3622182.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26663..26896
                     /gene="secG"
                     /locus_tag="VYR58_001006"
     CDS             26663..26896
                     /gene="secG"
                     /locus_tag="VYR58_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV3622183.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26998..29352
                     /gene="rnr"
                     /locus_tag="VYR58_001007"
     CDS             26998..29352
                     /gene="rnr"
                     /locus_tag="VYR58_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV3622184.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            29315..29782
                     /gene="smpB"
                     /locus_tag="VYR58_001008"
     CDS             29315..29782
                     /gene="smpB"
                     /locus_tag="VYR58_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV3622185.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29798..30658
                     /gene="tehB"
                     /locus_tag="VYR58_001009"
     CDS             29798..30658
                     /gene="tehB"
                     /locus_tag="VYR58_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV3622186.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30731..31684
                     /gene="coiA"
                     /locus_tag="VYR58_001010"
     CDS             30731..31684
                     /gene="coiA"
                     /locus_tag="VYR58_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV3622187.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31703..33505
                     /gene="pepF"
                     /locus_tag="VYR58_001011"
     CDS             31703..33505
                     /gene="pepF"
                     /locus_tag="VYR58_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV3622188.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            33507..34220
                     /locus_tag="VYR58_001012"
     CDS             33507..34220
                     /locus_tag="VYR58_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV3622189.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            34287..35228
                     /gene="prsA"
                     /locus_tag="VYR58_001013"
     CDS             34287..35228
                     /gene="prsA"
                     /locus_tag="VYR58_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV3622190.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(35347..35688)
                     /locus_tag="VYR58_001014"
                     /pseudo
     CDS             complement(35347..35688)
                     /locus_tag="VYR58_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            36100..36195
                     /locus_tag="VYR58_001015"
                     /pseudo
     CDS             36100..36195
                     /locus_tag="VYR58_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(36448..37068)
                     /locus_tag="VYR58_001016"
     CDS             complement(36448..37068)
                     /locus_tag="VYR58_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV3622191.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(37068..37550)
                     /locus_tag="VYR58_001017"
     CDS             complement(37068..37550)
                     /locus_tag="VYR58_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV3622192.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(37550..38392)
                     /locus_tag="VYR58_001018"
     CDS             complement(37550..38392)
                     /locus_tag="VYR58_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV3622193.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(38487..39287)
                     /locus_tag="VYR58_001019"
     CDS             complement(38487..39287)
                     /locus_tag="VYR58_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV3622194.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     TYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            39431..40810
                     /gene="glmU"
                     /locus_tag="VYR58_001020"
     CDS             39431..40810
                     /gene="glmU"
                     /locus_tag="VYR58_001020"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV3622195.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            40820..41365
                     /locus_tag="VYR58_001021"
     CDS             40820..41365
                     /locus_tag="VYR58_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV3622196.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            41377..41691
                     /locus_tag="VYR58_001022"
     CDS             41377..41691
                     /locus_tag="VYR58_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV3622197.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            41708..42400
                     /locus_tag="VYR58_001023"
     CDS             41708..42400
                     /locus_tag="VYR58_001023"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV3622198.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            42477..42968
                     /gene="rocS"
                     /locus_tag="VYR58_001024"
     CDS             42477..42968
                     /gene="rocS"
                     /locus_tag="VYR58_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV3622199.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            43066..43656
                     /locus_tag="VYR58_001025"
     CDS             43066..43656
                     /locus_tag="VYR58_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV3622200.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            43665..45428
                     /locus_tag="VYR58_001026"
     CDS             43665..45428
                     /locus_tag="VYR58_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV3622201.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT        13810 a         8368 c        10126 g        13332 t
ORIGIN      
        1 ctcccttgac ttgtgacaat cgcttgagcc ttcatagcgt agcatttctt tttaccagaa
       61 taattcgcta attctttttt tagggcgatt gatttttact tccgtcacat caatcattat
      121 cgtgtcctca gaactgagag gagttcttga aatcgtaaca ccactttgaa caagagttac
      181 ttcaacccat tggctccgac ggattaagtt gctttcgtga ataccaaaat cagccgcaat
      241 ttgctcataa gttcgatatt ctcgcacata ttgaagagtg gccataagaa ggtcttctag
      301 gcttaattta ggttttcgtc caccttttgc gtgtttaagt tgataagctg tttttaatac
      361 agctaatatc tcttcaaaag tcgtgcgctg aacaccaaca agacgcttaa atcgtgcatc
      421 agttagttgt ttacttgctt catcattcat agaactacta taccatattt tgtttcgcag
      481 gaagtctatt ggaaagtaag aaatattgaa gctgaggcga ttagaagaaa ttgtgagcgt
      541 ggtgctattt tttcaggtaa aataaaacat cacgaagatt ctcagtttaa aggagaccac
      601 tatgttgaat gttatgctgt tttagataat acggttatag caagagatag aataacagtc
      661 cctatcgatc cgttatgtgg aaaagatttt atagagtagc atataattga ttcttaactg
      721 gaatactctc tatctcttta catcaagaaa atgactaaac agggaagttt gccttcttcc
      781 ctttttttgt tatactagta gaagaaaaaa atagaaagat ttgtgggagt gaaaaagtcc
      841 gggggacttt ttcagcttga gccaagaaat tcgagagcga ggaaagtctg ggggactttt
      901 tcagcctgag ccaagaaact cgaaatctcg taagtctgat tggctttttc aatgtgaatc
      961 ttaacttcac actcccaaag aggtattagt gtcgtgtctc aatcttatat caatgttatc
     1021 ggtgctggtt tggcaggttc tgaagcagct taccaaatcg cagagcgtgg tattccagtt
     1081 aaactttatg aaatgcgtgg tgtcaagtct acaccccagc ataaaacaga caattttgct
     1141 gagttggttt gttccaattc tttgcgtggg gatgctttga caaatgcagt tggtcttctc
     1201 aaggaagaaa tgcgtcgctt gggttctgtt atcttggaat ctgctgaggc tacacgtgtt
     1261 cctgccggtg gagcccttgc ggtggatcgt gatggtttct ctcaaatggt gaccgaaaaa
     1321 gtggtcaacc accccttgat tgaagtggtg cgtgatgaaa ttacagaatt gccaacagat
     1381 gttattacag ttgtggcgac tggtcccttg actagcgatg ccctggctga aaagattcat
     1441 gcccttaata atggcgatgg cttctatttc tacgatgcag cagcgcctat tatcgatgtc
     1501 aacactatcg atatgagtaa ggtctatctc aaatctcgtt atgataaggg agaagcagcc
     1561 tatctcaatg ctccaatgac caagcaagag tttatggatt tccatgaagc cttggtcaat
     1621 gcggaagaag caccgctcaa ttcttttgaa aaagaaaagt actttgaagg atgtatgcca
     1681 atcgaagtta tggccaaacg tggcattaaa actatgcttt atggccctat gaagccagtc
     1741 ggtcttgagt atccggacga ctacatagga cctcgtgatg gagaatttaa aacaccttat
     1801 gcggttgtgc aacttcgtca ggataatgca gctggtagcc tatacaatat tgttggtttc
     1861 cagacccacc tcaaatgggg agaacaaaag cgtgtcttcc aaatgattcc gggtcttgaa
     1921 aatgcggagt ttgtccgtta tggtgtcatg catcgcaatt cttacatgga ttcaccaaat
     1981 cttcttgagc agacttaccg ttccaagaaa caaccaaatc tcttctttgc tggtcagatg
     2041 acgggggtgg aaggctatgt tgagtcggcg gcttcgggct tagttgcggg aattaacgca
     2101 gctcgtctct tcaaggaaga aagcgaggtt attttccccg agacgacagc gattggaagc
     2161 ttagctcatt acattaccca tgccgacagc aaacatttcc aaccaatgaa tgtcaatttt
     2221 gggatcatca aggagttgga aggcgagcgt atccgtgata agaaggctcg ttatgaaaaa
     2281 attgcagagc gtgcccttgc cgacttagag gaatttttga ctgtctaatt tttttgaaag
     2341 aattgttcat gatactataa aaatcttaga aattgtgata aaataggtag gatgaaagaa
     2401 ggagagtgaa aatggcgaat cccaagtata aacgtatttt aatcaagtta tcaggtgaag
     2461 cccttgccgg tgaacgtggc gtagggattg atatccaaac agttcaaaca atcgcaaaag
     2521 agattcaaga agttcatagc ttaggtatcg aaattgccct tgttattggt ggaggaaatc
     2581 tctggcgtgg agaacctgca gcagaagcag gtatggaccg tgttcaggca gattacactg
     2641 gaatgcttgg gactgttatg aatgctcttg tgatggcaga ttcattgcaa caagttgggg
     2701 ttgatacgcg tgtacaaaca gctattgcta tgcaacaagt ggcagagcct tatgtccgtg
     2761 gacgtgccct tcgtcacctt gaaaaaggcc gtatcgttat ctttggtgct ggaattggtt
     2821 caccatactt ctcgacagat acaacagcgg cccttcgtgc agctgaaatc gaagcagatg
     2881 ccatcctcat ggctaaaaat ggcgtcgatg gtgtgtacaa tgccgatcct aagaaggaca
     2941 agacagccgt taagtttgaa gaattgaccc accgtgatgt tatcaacaaa ggtcttcgta
     3001 tcatggactc aacagcctca accctctcaa tggacaacga cattgacttg gttgtcttca
     3061 acatgaacca atcaggcaac atcaaacgtg ttgtatttgg tgaaaatatc ggaacaacag
     3121 tttcaaataa tatcgaagaa aaggaataag aaagaatatg gctaacgtaa ttattgaaaa
     3181 agctaaagag agaatgaccc agtctcacca atcacttgct cgtgaatttg gtggtatccg
     3241 tgctggtcgt gccaatgcaa gcttgcttga ccgtgtacat gtagaatact atggagtcga
     3301 aactcctctt aaccaaatcg cttcaattac gattccagaa gcgcgtgttt tgttggtaac
     3361 accatttgac aagtcttcat tgaaagacat cgaacgtgcc ttgaacgctt ctgatcttgg
     3421 tatcacaccg gctaatgacg gttctgtgat tcgcttggtt atcccagctc ttacagaaga
     3481 aactcgtcgt gaccttgcta aagaagtgaa gaaggtcggc gaaaatgcta aagtggctgt
     3541 ccgcaatatc cgtcgcgatg ctatggacga agctaagaag caagaaaaag caaaagaaat
     3601 cactgaagac gaattgaaga ctcttgaaaa agatattcaa aaagtaacag acgatgctat
     3661 taaacacatc gacgacatga ctgctaacaa agagaaagaa cttttggaag tctaaaaata
     3721 aacagaaaaa ctcagttggc attgctggct gagttttatt cgaaagaagg aaatatgaat
     3781 acaaatcttg caagttttat cgttggactg atcatcgatg aaaatgaccg tttttacttt
     3841 gtgcaaaagg atggtcaaac ctatgctctt gctaaggaag agggccaaca tacagtaggg
     3901 gatacggtca aaggttttgc atacacggat atgaagcaaa aactccgcct gacaacctta
     3961 gaagtgactg ccactcagga ccaatttggt tggggacgtg tcacagaggt tcgtaaggac
     4021 ttgggtgtct ttgtggatac aggccttcct gacaaggaaa tcgttgtgtc actcgatatt
     4081 ctccctgtgc tcaaggaact ctggcctaag aagggcgacc aactctacat ccgtcttgaa
     4141 gtggataaga aagaccgtat ctggggcctc ttggcttatc aagaagactt ccaacgtctc
     4201 gctcgtcctg cctacaacaa catgcagaac caaaactggc cagccattgt ttaccgtctc
     4261 aagctgtcag gaacttttgt ttacctacca gaaaataata tgcttggttt tattcatcct
     4321 agcgagcgtt acgcagagcc acgtttgggg caagtattag atgcgcgcgt tattggtttc
     4381 cgtgaagtgg accgcactct gaacctctcc ctcaaaccac gctcctttga aatgttggaa
     4441 aacgatgctc agatgatttt gacttatttg gaaagcaatg gcggtttcat gaccttaaat
     4501 gacaagtcat ctccagacga catcaaggca acctttggca tttctaaagg tcagttcaag
     4561 aaagctttag gtggtcttat gaaggctggt aaaatcaagc aagaccagtt tgggacagag
     4621 ttgatttagg gaggcttatg agaaaatcat tttacacttg gctcatgacc gagcgcaatc
     4681 ctaaaagtaa cagtcccaaa gcaattttgg cagacctcgc ttttgaagag tcagcctttc
     4741 caaaacatac agatgatttt gatgaggtca gtcgcttttt ggaggagcat gccagtttct
     4801 cttttaacct aggagatttt gacagcattt ggcaggaata tctagaacac tagcatttat
     4861 tcattgggtt tgggctagta atttctccat ccctctgcta taataaaaag aaataaaagg
     4921 attagagagg ttctttattt gaaggaacat tcaatagaca ttcaactgag tcatccagat
     4981 gacctgtttc atctttttgg ttccaatgaa cgccatcttc gtttgatgga agaagagctt
     5041 gatgttgtga ttcatgctcg tacggagatt gtccaggttt tgggagaaga gtctgcctgt
     5101 gaggaagccc gtcaagttat tcaggctttg atggtcttgg taaatcgtgg gatgaccgtt
     5161 ggtacgccag atgtagtcac tgcgattagc atggtcaaaa atgatgaaat tgacaagttt
     5221 gtcgcccttt acgaagaaga aatcatcaaa gacaatactg ggaagcctat ccgagtcaaa
     5281 accttgggtc aaaaacttta tgtggacagt gtcaaacagc atgatgtgac ctttggaatc
     5341 ggacctgcag ggacagggaa gaccttcctt gcagtgacct tggcagtgac tgcccttaaa
     5401 cgtgggcaag tcaaacgaat tatcctgaca cgcccagcgg tggaagcagg agagagtcta
     5461 ggttttcttc cgggtgatct taaggagaag gtggatcctt accttcgtcc tgtttacgat
     5521 gccttgtatc aaattcttgg gaaagaccaa acgactcgtc tcatggagcg tgaaattatc
     5581 gaaattgcgc cccttgccta tatgcgtggc cggaccttgg atgatgcctt tgtcattctc
     5641 gatgaggcgc aaaacacgac catcatgcag atgaagatgt tcttgacgcg tttaggcttt
     5701 cattctaaga tgattgtcaa tggagatatc agtcagattg acctgccacg taatgtcaag
     5761 tccggtttga ttgatgctca agagaaactc aagaacatcc atcagattga ctttgttcat
     5821 ttttcagcca aggatgtggt tcgccatcca gttgtcgctc agattatccg agcctatgaa
     5881 tattctactg aagttgcaca cgactgattt tgaggaagtt cgcctgcaaa agaatatact
     5941 tttgagagag gaaaatccag ttgtataggc taaaggtttt atccaaaggt ttgagacaac
     6001 gattaggcac gatggaaaga acttttatgt ggctgatgac gatcagtgca tcttcctgtg
     6061 tcataatcac agggcacaag aaagtaggaa tttgaaaaga tgattgacca actatctaag
     6121 tattacagtt gtaggatact aactgaaaag gatattccaa gtattttatc tttatatgaa
     6181 agtaatcctc tgtattttca gcattgtcca ccagagccaa attttgcaac tgtaaaagag
     6241 gacatgcttt gtctacctga aggtaaagct aaggctgata agtttttttg ttggattttg
     6301 gaatggatct gaccttgtgg ctgttatgga ttttgtctat gcatatcctg atgaggagac
     6361 tgtttttatt ggtttgttta tggttgatcc agcctatcag aggaaaggga ttggtagtca
     6421 tattgtgaca gaagcactag cttattttgc taagaacttt cgaaaggcac gtttggctta
     6481 tgttaaggga aatccgcaat ctcagcattt ttgggaaaag cagggcttta aatcaattgg
     6541 atgcgaggtt aagaaagaac tctatacggt tgttatcgtt gaacagagcc tagaagatta
     6601 gaaatggcat caagtaagaa ctatttggaa tttgttttgg aacaattatc aggattagat
     6661 gatgtgactt accgttccat gatgggggag tatattcttt acttccgcgg caagattatt
     6721 ggcggcattt atgacgatcg cttttagtta aacccgtgca agcagtctta gataagattg
     6781 accaatcttc ttttgagttt ccatacaaag gtgccaaaga aatgatttga gtggaagaac
     6841 ttgataataa gatgtttcta taagacctga ttttagctat gtataaccaa ctgccaacgc
     6901 ccaaacctaa aaagaaaaag caagggtgaa cgaagtaaaa aagaagtctg ctaaggccct
     6961 gtctttgcac gggtaaaatt ttatatataa aaagaagctg ggactaaaga gctcagcttc
     7021 ctttggttta tataattgtc attacaagac gaagtggttg ggcgaaactc tgttgacttt
     7081 attcaattta gagtttctta tgcacaattg agtctggaac gaaagtctcc agttgcaaag
     7141 tatacagtac aataaaccaa cgatgtaata gctgatgaca caaagcacag tgggtaggac
     7201 ttgcgaagtc acccttttct tttcaaaatt tatactaaat cattgatatc agtgtagtca
     7261 cgattaagtc cttgagcaac tggtaggcta gtcaagtaac cttgataagt ggtcacacct
     7321 tgacgcaagc cttcatcttc agagattgct tgtgcgaatc ctttgccagc caaagcttcg
     7381 atataaggaa gagtgacatt ggttagggcg atggttgaag tgcgggcaac cgcaccaggg
     7441 atattggcaa cggcatagtg gagaacaccg tgtttttcat agacgggttc atcgtgcgtt
     7501 gtcacacggt cagctgtttc gataaggcca ccttggtcaa cagcaatgtc aacgatacag
     7561 agcctggacg catttgtttg accatctcat ctgtcaccaa ttccggtgct tttgcaccag
     7621 ggatgagaat ggctccaatc accacatcag catctctcac acttgcttca atgttgaatg
     7681 aattagacat aagagtttga atttgacttc caaagacttc ttctagaact gagagacgct
     7741 tggcactaat atctaaaata gtcacttgag caccaagacc aagggcgatg cgggcagcat
     7801 gtgtaccgac gacaccatca ccgatgatag ttacttttcc ttttggaaca cctggtacac
     7861 caccaagtag aacaccagag ccaccagctt gcttagtaag gaagtgagct ccgatttaaa
     7921 cagccatacg acctgcaacc tcactcatag gaacgaggag cggtagttgt ccttgattgt
     7981 cacgaacagt ttcataggca attcctgttg tttttgctgc taacatagca tctgctaatt
     8041 ctggagcagc ggccatgtgc aagtaggtga agagaagaag atcgtcgcgc aagtaaccgt
     8101 attcagaact taaaggttct tttactttca caaccaactc tgctgcccaa gcttcaccag
     8161 cagtagcgac aatctcagct ccttgctttt gatagtcagc atcagtaaag ccagaaccga
     8221 gaccagcatt tgtttcgata aggacacgat gaccacgact aactaagcta tgaacacctg
     8281 caggtgtgag ggcgacacgg ttttcgttat ttttaatttc ttttgggatt ccgattaaca
     8341 ttgagataac ctacctttca attgacggtc ttgttttggt tgtcacattc cagttcataa
     8401 atcaaaaatg tgacggtttc attgtatatg aaaccgcttc aaaaatcaag aaaaacttgt
     8461 catccaaatt ttttatgcta gactagtgaa aatcaagctt tgattggttg gaaaagtatg
     8521 gaatcaattt ttgtaaaact tgcccagtat ccgtctatag aaacggagcg tttattgctt
     8581 agacctgtaa ctttggatga tgcggaagca atgtttgact atgcctcgga caagggtaat
     8641 acacgttaca cttttccaac caatcaaagc ttggaagaaa ccaagaataa cattgctcag
     8701 ttctatttgg ctaatccctt gggacgttgg ggaatagaac taaaaagcaa tggtcagttt
     8761 attggaacca ttgacttgca caagattgat tctgttctta agaaggcagc tattggctac
     8821 attatcaata aaaagtattg gaatcaagga ttaacgacag aagccaatcg tgctgtgatt
     8881 gagctagctt ttgagaagat agggatgaat aagttgactg cccttcacga taaggacaat
     8941 cctgcgtcag gaaaggtcat ggagaaatca ggcatgcgtt tttcccatgc agaaccatat
     9001 gcttgtatgg accagcatga aaaagatcga atcgttacaa gagttcatta tgtcttgacc
     9061 aaggaagact attttgcaaa taaataagca gttgaaaaga aatttttcga ctgttttttc
     9121 ttcatcttac gaataatcta agagaggaga aaatatggaa gcaattatcg agaaaatcaa
     9181 agagtataaa atcatcgtca tctgtactgg tctgggcttg cttgtaggcg gatttttcct
     9241 gctaaagcca gctccacaaa cacctgtcaa agaaacgaat ttgcaggctg aagttgcagc
     9301 tgtttccaag gatttggtat ccgaaaagga agtgaagaag gaagagaagg aagaacccct
     9361 tgaacaagat ctaatcacag tagatgtcaa aggtgctgtc aaatcgccag ggatttatga
     9421 cttgcctgta ggtagtcgag tcaatgatgc tgttcagaag gctggtggct tgacagagca
     9481 agcagacagc aagtcgctca atctagctca gaaagttagt gatgaggctc tggtttacgt
     9541 tcctactaag ggagaagaag cagttagcca acagactggt ttggggacag cttcttcaat
     9601 aagcaaggaa aagaaggtca atctcaacaa ggccagtctg gaagaactca agcaggtcaa
     9661 gggactggga ggaaaacgag ctcaggacat tatcgaccat cgtgaggcaa atggcaagtt
     9721 caagtcagta gacgaactca agaaggtctc tggcattggt ggcaaaacaa tagaaaagct
     9781 taaagactat gttacagtgg attaagaatt tctctattcc cctaatttac ctgagttttc
     9841 tattactttg gctttattac gctattttct cagcatctta tcttgctttg ttgggctttg
     9901 tttttctgct agtctgtctc tttatccaat ttccgtggaa atctgctggt aaagttctag
     9961 tgatttgtgg aatctttgga ttttggtttg tttttcaaaa ttggcaacag agtcaagcga
    10021 gtcaaaatct ggcggattct gttgaagggg tacggatttt gcctgatact attaaggtta
    10081 atggtgatag tctatccttt cgtggcaagt ctaacggtcg tgctttccaa gtctattata
    10141 aactccagtc cgaggaggag aaagaagcct ttcaagcttt aaccgacctg catgagatag
    10201 gactagaagg gaagctttcg gagccagaag ggcagagaaa ttttggtggc tttaattacc
    10261 aagcctatct gaagactcag ggaatttacc agactctcaa tatcaaaaca atccagtcac
    10321 ttcaaaagat tggcagttgg gatataggag aaaacttgtc cagtttacgt cgaaaggctg
    10381 tggtttggat taagacgcac tttccagacc ctatgcgcaa ttacatgaca ggactcttgc
    10441 tgggacatct ggacaccgac tttgaggaga tgaatgagct ttattccagt ctaggaatta
    10501 tccacctctt tgccctatct ggtatgcagg taggtttttt catgaatgga tttaagaaac
    10561 ttctcttgcg attgggcttg acccaagaaa agttgaaatg gctgacttat cccttttccc
    10621 ttatctatgc gggactaact ggattttcag catcggttat tcgcagtctc ttgcaaaagc
    10681 tactggctca acatggggtt aagggcttgg ataattttgc cttgacggtg cttgtcctct
    10741 ttattgtcat gccaaacttt ttcttgacag caggaggagt cttgtcctgc gcttatgctt
    10801 ttatcctgac catgaccagc aaagaagggg aggggctcaa ggctgttact agtgaaagtc
    10861 tagtcatctc cttgggcata ttgcccattc tatccttcta ttttgcggaa tttcaacctt
    10921 ggtctatcct tttgaccttt gtcttttcct ttctatttga cttgaccttc ttaccgctct
    10981 tgtctatttt atttgtcctt tcctttctct atccagtcat tcagctgaac tttatttttg
    11041 aatggttgga gggcattatt cgcttggtgt cacaggtgac aagtagacct ctggtctttg
    11101 gacaacccaa tgcatggttt ttaatcctat tgttaatttc cttggctttg gtctatgatt
    11161 tgagaaaaaa cattaaaaag ctaacggtat tgtgcttatt gattacaggg ctctttctcc
    11221 tgaccaagca tccactggaa aatgaaatca ccatgctgga tgtggggcaa ggagaaagta
    11281 ttttcctacg ggatgtaact gggaaaacca ttctcataga tgtaggtggt aaggcagaat
    11341 cttataagaa aatcgaaaaa tggcaagaaa agatgacgac cagcaatgcc cagcgaacct
    11401 tgattcccta tctcaaaagt cgaggagtag ctaagattga ccagctaatt ttgactaaca
    11461 cggacaagga gaatgttgga gatttgtcag aggtgaccaa ggctttccat gtaggggaga
    11521 ttctagtatc aaaagacagt ctgaaacaga aggaatttgt ggcagaacta caggcgactc
    11581 aaacaaaggt gcgtagtatg acagtagggg agaacttgcc catttttgga agtcagttag
    11641 aagttctatc tccaaggaaa atgggagatg gaggacacga tgatacccta gttctgtatg
    11701 ggaaattctt ggataagcaa tttctcttca cgggaaattt ggaggagaaa ggagagaagg
    11761 acttgctgaa gcactatcca gacttgaaag taaatgtttt gaaagctagc caacatggca
    11821 ataaaaaatc atcaagtcca gcctttctag aaaaactcaa accagagctt actcttatct
    11881 cagttggaaa gagcaatcga atgaaactcc cccatcagga aacattgaca cgactggaag
    11941 gtatcaatag caaagtttat cgaactgacc agcaaggagc tatacgtttt aaggggttgg
    12001 atagttggaa aatcgaaagt gttcgatagg aaggataaat gttgtagatt agtgaaataa
    12061 actaaaaatt tgttgcataa taatgataaa aatggtataa tgaaaacgta ttcaatattg
    12121 aggatataaa atcattaaaa atcagcaaaa gttgttttat tagttagttt ataatctatt
    12181 ggtcttcttc agtccagtgt atctgctgtg acagtcacta aaagttacaa gtatgattgg
    12241 aatacggttt gggaatatag taccaactat cacgaccatc agtatgcttg gattccgtca
    12301 tggtctcgtt atgacagcta ttctgagtat aaagttggcg gaggctggaa ctacgctcgt
    12361 tatgaggtca taaactatta cagcggaggc tattaattct taaagagtga gaaaaaggag
    12421 ggctagatat gttgcagctt actcatgtga ccttaaaaac gcgacaagtc atcttgcaag
    12481 atgtggattt cacctttaaa aagggtaggg tttatggtct tcttgctatc aatggctctg
    12541 gaaagacgac cctgttccgt gccattagca atttaattcc cataagtagt ggaaatatcg
    12601 cagcccctcc ttctttattt tattatgaga gtattgaatg gctggatgga aacttaagtg
    12661 ggatggacta ccttcgtctt atcaaaaaca tctggaagtc aggtctgaac ttgagggatg
    12721 aaatcgccta ttgggaaatg tctgactata tcagtcttcc cattcgcaag tattccttag
    12781 gcatgaagca acgcttggtg attgccatgt atttcctcag tcaggccaaa tgctggctca
    12841 tggatgagat tacaaatggc ttagatgagt attatcgaca gaagtttttt gataggctag
    12901 cacaaatcga tagacaagaa cagctggttc ttttaagttc ccactataag gaagagttgg
    12961 ttgatgtctg cgatagagta gtaaccattc atcaggggca gatagaagag gtttagttta
    13021 tgaaagatgt tagtctattt ttattgaaaa aagttttcaa aagccgctta aactggattg
    13081 tcttagcttt atttgtatct gtactcggtg ttacctttta tttaaatagt cagactgcaa
    13141 actcacacag cttggagagc aggttggaaa gtcgcattgc agccaacgag agggctatca
    13201 atgaaaatga agagaaactc tcccaaatgt ctgataccag ctcggaggaa taccagtttg
    13261 ctaaaaataa tttagacgtg caaaaaaatc ttttgacgcg aaagacagaa attctaactt
    13321 tactaaaaga agggcgctgg aaagaagcct actatttgca gtggcaagat gaagagaaga
    13381 attatgaatt tgtatcaaat gacccgactg ctagccctgg cttaaaaatg ggggttgacc
    13441 gcgaacggaa gatttaccaa gccctgtatc ccttgaacat aaaagcacat actttggagt
    13501 ttccgaccca cgggattgat cagattgtct ggattttaga ggttatcatc ccaagtttgt
    13561 ttgtggttgc tattattttt atgctaacac aactatttgc agaaagatat caaaatcatc
    13621 tggacacagc tcacttatat cctgtttcaa aagtgacatt tgcaatatcc tctcttggag
    13681 ttggagtggg atatgtaact gtgctgttta tcggaatctg tggcttttct tttctagtgg
    13741 gaagtctgat aagtggtttt ggacagttag attatcccta cccaatttat agcttagtga
    13801 atcaagaagt aactattggg aaaatacaag atgtattatt tcctggcttg ctcttagctt
    13861 tcttagcctt tatcgtcatt gtggaagttg tgtacttgat tgcttacttt ttcaagcaaa
    13921 aaatgcctgt cctctttctt tcactcattg ggattgttgg cttattgttt ggtatccaaa
    13981 ccattcagcc tcttcaaagg attgcacatc tgattccctt tacttacttg cgttcagtgg
    14041 agattttatc tggaagatta cctaagcaga ttgataatgt cgatctaaat tggagcatgg
    14101 gaatggtctt acttccttgc ctgattatct ttttgctatt gggaattcta tttattgaaa
    14161 gatggggaag ttcacagaaa aaagaatttt ttaatagatt ctagctttcc tataggtagg
    14221 gaaaataagt aaaaactaac atagagaggg aatcaacttg attctctctt tttgattcga
    14281 aaaccaaacc aaaatacaaa cacaaacttt tcaaaaaata actttttatc ttgacaagag
    14341 ctagaaaact tggtatcata taaaagttga gaaaagcaga agtgagagct tctcgccttg
    14401 tgacattaag ttgcctggcc ctacggatga aaagtttcga agaaacgcta tcataacgtg
    14461 cgggcttgta tatttacaag tccgctattg tttttctcta ataaaacaaa agaggtgaaa
    14521 accatagcaa agcaagactt attcatcaat gatgagattc gtgtacgtga agttcgcttg
    14581 attggtcttg aaggagaaca gctaggtatc aagccactca gtgaagcgca agctttggct
    14641 gataacgcta atgttgacct agtattgatt caaccccaag ccaaaccgcc tgttgcaaaa
    14701 attatggact acggtaagtt caaatttgag taccagaaga agcaaaaaga acaacgtaaa
    14761 aaacaaagcg ttgttactgt gaaagaagtt cgtctaagtc caactattga caagggtgac
    14821 tttgatacaa aacttcgtaa tgcacgtaag ttccttgaaa aaggaaataa agttaaggta
    14881 tctattcgct ttaagggtcg tatgattacc cataaagaga ttggtgcaaa agttttagcc
    14941 gagtttgctg aagcaactca agatattgcc atcatcgaac aacgtgctaa aatggatgga
    15001 cgtcaaatgt tcatgcaatt ggcgccagcg actgacaaaa aataattgtc agaaagttaa
    15061 ataaaggaga aaaaatcatg ccaaaacaaa aaacacaccg cgcatcagct aaacgtttca
    15121 aacgtacagg ttctggtgga cttaaacgtt tccgtgctta cacttctcac cgtttccacg
    15181 gaaaaactaa gaaacaacgt cgtcatcttc gtaaagcatc tatggtgcat tcaggagatt
    15241 acaaacgtat caaagcaatg cttactcgct tgaaataata gcttgactgt aagtaaacaa
    15301 ttctaggaaa tatttggagg aaataaaaca tggcacgtgt taaaggtggc gttgtatcac
    15361 gcaaacgtcg taaacgtatt cttaaattag caaaaggtta ctatggagct aaacacatct
    15421 tgttccgtac tgcaaaagaa caagtaatga actcttacta ctatgcatac cgtgaccgtc
    15481 gtcagaaaaa acgtgacttc cgcaaattgt ggattactcg tatcaatgcg gcagctcgta
    15541 tgaacggact ttcatactca caattgatgc atggtttgaa attggctgag attgaagtta
    15601 accgtaaaat gcttgctgac ttggctgtta acgatgcagt agctttcaca gctcttgcag
    15661 atgcagctaa agcaaaactt ggtaaataat aactgatgag actggaacag gattgtccag
    15721 tctttttaaa aataaaggag aaagatatgg cttcaaaaat gctacacact tgcttacgag
    15781 tagaaaatct tgaaaaatca atcgcatttt atcaagatgc ttttggtttt aaagaattgc
    15841 gtcgcagaga ttttccagac catgccttca cgattgtcta tctaggtctt gagggtgatg
    15901 attatgagtt ggagttgact tataactacg atcacggtcc gtatgtggtt ggtgatgggt
    15961 ttgcccatat cgccctcagt acacctgatc ttgaggcact tcatcaagaa cacagtgcaa
    16021 aaggctatga agtgactgag ccaaatggtc taccaggaac tacaccaaac tattactttg
    16081 ttaaagaccc tgatggatat aaggtcgaag tcattcgtga aaaataattt cgtgcaagtt
    16141 aagtagaata ttcgttttct acttgacttt ttttagctga aagagtatac taataaaaat
    16201 tcaaccttta aggggagtcc agagagactc acaaggtgtc agataaaaga atagtgcaat
    16261 tttctagagg agaccttttg agtgtgctct cttgtgttgt acgattttaa ctgaggcctt
    16321 gcactagcaa ggtcttttct ttatctggtc cccttaaaat ttaaggagga aaagttatga
    16381 atctcacatg taagaagcgt ttgggtgtca ttcggttgga aaccatgaag gtggttgcac
    16441 aagaggaaat cgcgccagca atctttgaat tagtcctaga aggagaaatg gttgaagcca
    16501 tgcgagcagg ccaatttctt catctgcgtg taccagacga tgcccatctc ttacgtcgtc
    16561 ctatttcaat ttcgtctatt gacaaggcaa acaagcagtg tcacctcatt tatcggattg
    16621 agggagctgg gactgcaatt ttttcaacct taagtcaggg agacactctt gatgtgatgg
    16681 ggcctcaggg aaatggtttt gacttgtctg accttgatga gcagaatcag gttctccttg
    16741 ttggtggtgg gattggtgtt ccacccttgc ttgaggtggc caaggaattg catgaacgtg
    16801 gagtgaaagt agtgacagtc ctcggttttg ctaataagga tgctgttatt ttgaaaacgg
    16861 aattggctca gtatggtcag gtctttgtaa cgacagatga tggttcttat ggcatcaagg
    16921 gaaatgtttc cgttgttatc aatgatttag atagtcagtt tgatgctgtt tactcgtgtg
    16981 gggctccagg aatgatgaag tatatcaatc aaacctttga tgatcaccca agagcctatt
    17041 tatctctgga atctcgtatg gcttgtggga tgggagcttg ctatgcctgt gttctaaaag
    17101 taccagaaag cgagacggtc agccaacgcg tctgtgaaga tggtcctgtt ttccgcacag
    17161 gaacagttgt attataagga gaaaattatg actacaaatc gattacaagt gtctctacct
    17221 ggtttggatt tgaaaaatcc gattattcca gcatcaggct gttttggctt tggacaagag
    17281 tatgccaagt actatgattt aaacctttta ggttctatta tgatcaaggc gacaaccctt
    17341 gaaccacgtt ttgggaaccc aactccaaga gtagcagaga cgcctgctgg tatgctcaat
    17401 gcaattggct tgcaaaatcc tggtttagag gttgttttgg ctgaaaagct accttggctg
    17461 gaaagagaat atccaaatct tcctattatt gccaatgtag ctggtttttc aaaacaagag
    17521 tatgcagctg tttctcatgg gatttccaag gcaactaatg taaaagctat cgagctcaat
    17581 atttcttgtc ccaatgttga ccactgtaat catggacttt tgattggtca agatccagat
    17641 ttggcttatg atgtggtgaa agcagctgtg gaagcctcag aagtgccagt ttatgtcaaa
    17701 ttaaccccga gtgtgaccga tatcgttact gtcgcaaaag ctgcagaaga tgcgggagca
    17761 agtggcttga ccatgatcaa tactctggtt ggaatgcgct ttgacctcaa aaccagaaaa
    17821 ccaatcttgg ccaatggaac aggtggaatg tcaggtccag cagtctttcc agtagccctc
    17881 aaactcatcc gccaagtagc ccaaacaaca gacctgccta tcattggaat ggggggagtg
    17941 gattcggctg aagctgccct agaaatgtat ctggctgggg catctgctat cggagttgga
    18001 acagctaact ttaccaatcc ttatgcctgc cctgacatca tcgaaaattt accaaaagtc
    18061 atggataaat acggtattag cagtctggaa gaactccgtc aggaagtaaa agagtctctg
    18121 aggtaaactg caatcaatct gttcttgatt ttttattagt ttgtaatatg aatttaggag
    18181 aattttggta caataaaata aataagaaca gaggaagaag gttaatgaag aaagtaagat
    18241 ttattttttt agctctgcta tttttcttag ctagtccaga gggtgcaatg gctagtgatg
    18301 gtacttggca aggaaaacag tatctgaaag aagatggcag tcaagcagca aatgagtggg
    18361 tttttgatac tcattatcaa tcttggttct atataaaagc agatgctaac tatgctgaaa
    18421 atgaatggct aaagcaaggt gacgactatt tttacctcaa atctggtggc tatatggcca
    18481 aatcagaatg ggtagaagac aagggagcct tttattatct tgaccaagat ggaaagatga
    18541 aaagaaatgc ttgggtagga acttcctatg ttggtgcaac aggtgccaaa gtaatagaag
    18601 actgggtcta tgattctcaa tacgatgctt ggttttatat caaagcagat ggacagcacg
    18661 cagagaaaga atggctccaa attaaaggga aggactatta tttcaaatcc ggtggttatc
    18721 tactgacaag tcagtggatt aatcaagctt atgtgaatgc tagtggtgcc aaagtacagc
    18781 aaggttggct ttttgacaaa caataccaat cttggtttta catcaaagaa aatggaaact
    18841 atgctgataa agaatggatt ttcgagaatg gtcactatta ttatctaaaa tccggtggct
    18901 acatggcagc caatgaatgg atttgggata aggaatcttg gttttatctc aaatttgatg
    18961 ggaaaatggc tgaaaaagaa tgggtctacg attctcatag tcaagcttgg tactacttca
    19021 aatccggtgg ttacatgaca gccaatgaat ggatttggga taaggaatct tggttttatc
    19081 tcaaatctga tgggaaaata gctgaaaaag aatgggtcta cgattctcat agtcaagctt
    19141 ggtactactt caaatccggt ggttacatga cagccaatga atggatttgg gataaggaat
    19201 cttggtttta cctcaaatct gatgggaaaa tagctgaaaa agaatgggtc tacgattctc
    19261 atagtcaagc ttggtactac ttcaaatctg gtggctacat ggcgaaaaat gagacagtag
    19321 atggttatca gcttggaagc gatggtaaat ggcttggagg aaaaactaca aatgaaaatg
    19381 ctgcttacta tcaagtagtg cctgttacag ccaatgttta tgattcagat ggtgaaaagc
    19441 tttcctatat atcgcaaggt agtgtcgtat ggctagataa ggatagaaaa agtgatgaca
    19501 agcgcttggc tattactatt tctggtttgt caggctatat gaaaacagaa gatttacaag
    19561 cgctagatgc tagtaaggac tttatccctt attatgagag tgatggccac cgtttttatc
    19621 actatgtggc tcagaatgct agtatcccag tagcttctca tctttctgat atggaagtag
    19681 gcaagaaata ttattcggca gatggcctgc attttgatgg ttttaagctt gagaatccct
    19741 tccttttcaa agatttaaca gaggctacaa actacagtgc tgaagaattg gataaggtat
    19801 ttagtttgct aaacattaat aatagccttt tggagaacaa gggcgctact tttaaggaag
    19861 ccgaagaaca ttaccatatc aatgcccttt atctccttgc ccatagtgcc ctagaaagta
    19921 actggggaag aagtaaaatt gccaaagata agaataattt ctttggcatt acagcctatg
    19981 atacgacccc ttacctttct gccaagacat ttgatgatgt ggataaggga attttaggtg
    20041 caaccaagtg gattaaggaa aattatatcg ataggggaag aactttcctt ggaaacaagg
    20101 cttctggtat gaatgtggaa tatgcttcag acccttattg gggcgaaaaa attgctagtg
    20161 tgatgatgaa aatcaatgag aagctaggtg gcaaagatta gtactataag tgaatatgat
    20221 ttgagtgaat agtaagttaa aaatcctgat ttcaagtaaa atcaggattt tttcatggat
    20281 gcaatttttt tggagtctgg tgtgacgcgg agggtctttt gtcctgtgta agtgacaaag
    20341 ccgggttttc caccagttgg tttattgagt tttttgactt caatcatatc tacctgcacc
    20401 agattcgaca ggcgcccttg agagaagtag gcagctaact ctgctgcgtc tgtcttgact
    20461 gcatcagatg ggtcaagatt tcctgagatg acaacatggc ttccaggaat gtccttagca
    20521 tggaaccaaa gttcctcctt gcgggccatt ttaaaggtca attcctcatt ttgaagattg
    20581 tttcgtccga catagatgat ggttttgcca tcgcttgcta gatattgttc tagttttttg
    20641 cgtttctgga ttttctcccg ttgtcttctg cggataaaac ctgtttgaat caattcttca
    20701 cggatttcag cgatttcttc cagtccagct tggttgagga cggtttctac actttccaga
    20761 tagagaatag tggctttggt ttcttcaatc aaatcagtca agtatttgac agcttctttg
    20821 agtttctgat accgtttaaa atagcgttgg gcattctggt tgggagtcag agccttatca
    20881 agcgcaatca tgataggttg gttggtatag tagttgtcta ggataacctg gtcttggtcg
    20941 ttaggcactt ggtggaggaa ggttgtcagc aattctcctt tttgacgaaa ttcttcagcg
    21001 ttgtctgtcg ccagtaactc tttttcctgt tttttgagtt tgtgtcggtt tttctgaagt
    21061 tcattttcaa cacgacgaat cagttcactg gcctgctgtt tgacgcggtc gcgctcagcc
    21121 ttatccttat agtaggtgtc caacaaatca gaaagatttg caaaaggctc tcccacctga
    21181 tttgcaaaag gaactggact gaaggaagtc tcagtcaagc atggcttggt ttcctgattg
    21241 aaaaaatttc ggaaagcgga aagtttttca ctaaccagta tcctttccaa ttcatttgcc
    21301 gtatcgcgtc ccagaccttg aaagaggctt tgaagatttt ttgctgttag ttcttgggtt
    21361 tgcaggattt caaagagctt ttcatccttg atagtaaaag gattgagaga ttctgtactt
    21421 ggcggagcga tataggtcga tcctggaagt aaggtgcggt agctattttg tgaaaaaccg
    21481 acgtgtttga taacttcgag gattttatga ctgcttttat cgaccagtag aatattactg
    21541 tgtttcccca taatttcgat aatcaaggta gcctggatat ggtctccaat ctcgttttta
    21601 ttggaaactg tcatttccac aatacggtca ttttccactt gctcaatcga ctcaatcagg
    21661 gccccctgca aatactttct caaaaccatg ataaaggtag aaggttgggc tggattttca
    21721 aaagtcgttt gggtcagctg aatgcgtcca aaaactggat gggcagaaag gagcaggcga
    21781 tggctttggc gattgctgcg gatttgcaag accaactctt gttcaaaagg ctgattgatt
    21841 ttctggatgc gaccattcac taattcgctt cgcaattcct caactatgtg gtgtaaaaaa
    21901 aatccgtcaa atgacatcgt tctctccttg tgattgtatt ccatagtatt atatcaaaaa
    21961 ggtagaataa aatcatggaa atgtggtata ataaagccaa gtaaagagaa acgagaagca
    22021 catgtatatt gaaatggtag atgaaactgg tcaagtttca aaagaaatgt tgcaacaaac
    22081 ccaagaaatt ttggaatttg cagcccaaaa attaggaaaa gaagacaagg agatggcagt
    22141 cacttttgtg accaatgagc gtagtcatga acttaatctg gagtaccgtg acaccgaccg
    22201 tccgacagat gtcatcagcc ttgagtataa accagaattg gaaattgcct ttgacgaaga
    22261 ggatttgctt gaaaatccag aattggcaga gatgatgtct gagtttgatg cctatattgg
    22321 ggaattgttc atctctatcg ataaggctca tgagcaggcc gaagaatatg gtcacagctt
    22381 tgagcgtgag atgggcttct tggcagtaca cggcttttta catattaacg gctatgatca
    22441 ctacactccg gaagaagaag cggagatgtt cggtttacaa gaagaaattt tgacagccta
    22501 tggactcaca agacaataaa cgaaaatgga aaaatcgtga cctgatatcc agtttagaat
    22561 ttgccatcac agggattttt actgctatca aggaagaacg aaatatgcga aaacatgcag
    22621 tgacggctct agtggttatc cttgcaggtt ttgtttttca ggtgtcacga atcgaatggc
    22681 tctttctcct attgagcatt ttcttggtag tagcctttga gattatcaac tctgctattg
    22741 aaaatatggt ggatttggcc agtcactatc acttttccat gctggctaaa aatgccaagg
    22801 atatggcggc tggcgcggta ttagtggttt ctcttttcgc agccttaaca ggtgcattga
    22861 tttttctccc acgaatctgg gatttattat tttaaacagt aagaggaaat tatgactttt
    22921 aaatcaggct ttgtagccat tttaggacgt cccaatgttg ggaagtcaac ctttttaaat
    22981 cacgttatgg ggcaaaagat tgccatcatg agtgacaagg cgcagacaac gcgcaataaa
    23041 atcatgggaa tttacacgac tgataaggag caaattgtct ttatcgacac accagggatt
    23101 cacaaaccta aaacagctct cggagatttc atggttgagt ctgcctacag tacccttcgc
    23161 gaagtggaca ccgttctttt catggtgcct gctgatgaag cgcgtggtaa gggggacgat
    23221 atgattatcg agcgtctcaa ggctgccaag gttcctgtga ttttggtggt gaataaaatc
    23281 gataaggtcc atccagacca gctcttgtct cagattgatg acttccgtaa tcaaatggac
    23341 tttaaggaaa ttgttccaat ctcagccctt cagggaaata acgtgtctcg tctagtggat
    23401 attttgagtg aaaatctgga tgaaggtttc caatatttcc cgtctgatca aatcacagac
    23461 catccagaac gtttcttggt ttcagaaatg gttcgcgaga aagtcttgca tctaactcgt
    23521 gaagagattc cgcattctgt agcagtagtt gttgactcta tgaaacgaga cgaagagaca
    23581 gacaaggttc acatccgtgc aaccatcatg gttgagcgcg atagccaaaa agggattatc
    23641 atcggtaaag gtggcgctat gcttaagaaa atcggtagca tggcccgtcg tgatatcgaa
    23701 ctcatgctag gagacaaggt cttcctagaa acctgggtca aggtcaagaa aaactggcgc
    23761 gataaaaagc tagatttggc tgactttggc tataatgaaa gagaatacta agtagaggta
    23821 ggctcatgcc tgcttcttgt ttttacagaa ggagacttat gcctgaatta cctgaggttg
    23881 aaaccgtttg tcgtggctta gaaaaattga ttataggaaa gaagatttcg agtatagaaa
    23941 ttcgctaccc caagatgatt aagacggatt tggaagagtt tcaaagggaa ttgcctagtc
    24001 agattatcga gtcaatggga cgtcgtggaa aatatttgct tttttatctg acagacaagg
    24061 tcttgatttc ccatttgcgg atggagggca agtattttta ctatccagac caaggacctg
    24121 aacgcaagca tgcccatgtt ttctttcatt ttgaagatgg tggcacgctt gtttatgagg
    24181 atgttcgcaa gtttggaacc atggaactct tggtgcctga ccttttagac gcctacttta
    24241 tttctaaaaa attaggtcct gaaccaagcg aacaagattt tgatttacag gtctttcaat
    24301 ctgcccttgc caagtccaaa aagcctatca aatcccatct cctagaccag accttggtag
    24361 ctggacttgg caatatctat gtggatgagg ttctctggcg agctcaggtt catccagcta
    24421 gaccttccca gactttgaca gcagaagaag cgactgccat tcatgaccag accattgctg
    24481 ttttgggcca ggctgttgaa aaaggtggct ccaccattcg gacttatacc aatgcctttg
    24541 gggaagatgg aagcatgcag gactttcatc aggtctatga taagactggt caagaatgtg
    24601 tacgctgtgg taccatcatt gagaaaattc aactaggcgg acgtggaacc cacttttgtc
    24661 caaactgtca aaggagggac tgatgggaaa aatcatcgga atcactgggg gaattgcctc
    24721 aggtaagtca actgtgacaa attttctaag acagcaaggc tttcaagcag tggatgccga
    24781 cgcagtcgtt caccaactac agaaacctgg tggtcgtctg tttgaggcta tagtacagca
    24841 ctttgggcaa gaaatcattc ttgaaaacgg agaactcaat cgccctctcc tagctagtct
    24901 catcttttca aatcctgaag agcaaaaatg gtctaatcaa attcaagggg agattatccg
    24961 tgaggaactg gctactttga gagaacaatt ggctcagaca gaagagattt tcttcatgga
    25021 tattccccta ctttttgagc aggactacag cgattggttt gctgagactt ggttggtcta
    25081 tgtggaccga gatgcccaag tagaacgctt aatgaaaagg gaccagttgt ccaaagatga
    25141 agctgagtct cgtctggcag cccagtggcc tttagaaaaa aagaaagatt tggccagcca
    25201 ggttcttgat aataatggca atcagaacca gcttcttaat caagtgcata tccttcttga
    25261 gggaggtagg caagatgaca gagattaact ggaaggataa tctgcgtatt gcctggtttg
    25321 gtaattttct gacaggagcc agtatttctt tggttgtacc ttttatgccc atcttcgtgg
    25381 aaaatctagg tgtagggagt cagcaagtcg ctttttatgc aggcttagca atttctgtct
    25441 ctgctatttc cgcggcgctc ttttctccta tttggggtat tcttgctgac aaatacggcc
    25501 gaaaacccat gatgattcgg gcaggtcttg ctatgactat cactatggga ggcttggcct
    25561 ttgtcccaaa tatctattgg ttaatctttc ttcgtttact aaacggtgta tttgcaggtt
    25621 ttgttcctaa tgcaacggca ctgatagcca gtcaggttcc aaaggagaaa tcaggctctg
    25681 ccttaggtac tttgtctaca ggcgtagttg caggtactct aactggtccc tttattggtg
    25741 gctttatcgc agaattattt ggcattcgta cagttttctt actggttggt agttttctat
    25801 ttttagctgc tattttgact atttgcttta tcaaggaaga ttttcaacca gtagccaagg
    25861 aaaaggctat tccaacaaag gaattgttta cttcagttaa atatccctat cttttgctca
    25921 atctcttttt aaccagtttt gtcatccaat tttcagctca atcgatcggc cctattttgg
    25981 ctctttatgt acgcgactta gggcagacag agaatcttct ttttgtctct ggtttgattg
    26041 tgtccagtat gggcttttcc agcatgatga gtgcaggagt catgggcaag ctaggtgaca
    26101 aggtgggcaa tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc atctatctcc
    26161 tctgtgccaa tgcctctagc ccccttcaac taggactcta tcgtttcctc tttggattgg
    26221 gaaccggtgc cttgattccc ggggttaatg ccctactcag caaaatgact cccaaagccg
    26281 gcatttcgag gatctttgcc ttcaatcagg tattctttta tctgggaggt gttgttggtc
    26341 ccatggcagg ttctgcagta gcaggtcaat ttggctacca tgctgtcttt tatgcgacaa
    26401 gcctttgtgt tgcctttagt tgtctcttta acctgattca atttcgaaca ttattaaaag
    26461 taaaggaaat ctagtgcgag taaaaattaa tctcaaatgc tcctcttgtg gcagtatcaa
    26521 ttacctaacc agtaaaaatt caaaaaccca tccagacaag attgaggttt taaagtattg
    26581 tcccaaggaa agaaaagtaa ccctacatct tgaatctaag tagattttat ggtaaaataa
    26641 tagggatttt aaggagtttg atatgtataa cctattatta accattttat tagtattatc
    26701 tgttgtgatt gtgattgcaa ttttcatgca accaaccaaa aaccaatcca gcaatgtatt
    26761 tgatgccagt tcaggtgatt tgtttgaacg cagtaaagct cgcggttttg aagctgtaat
    26821 gcagcgtttg acagggattt tagtcttttt ctggctagcc attgccttag cattgacggt
    26881 attatcaagt agataagaaa ataatgggca ggactaggtc tttgcctctt tttattttta
    26941 aaggatgttt gagaaggttt tacagtaaaa gaaaattaaa aaatctagaa agaaaatatg
    27001 aaagatagaa taaaagaata tttacaagac aagggaaagg tgactgttaa tgatttggct
    27061 caggctttgg gaaaagacag ttccaaggat tttcgtgagt tgattaaaac cttgtcctta
    27121 atggaaagaa agcaccagat tcgctttgaa gaagatggta gtctgacatt agaaattaag
    27181 aaaaaacatg agattaccct caaggggatt tttcatgccc ataaaaatgg ctttggcttt
    27241 gttagtctgg aaggcgagga ggacgacctt tttgtaggga aaaatgatgt caactatgct
    27301 attgatggtg ataccgtcga ggtagtgatt aagaaagtcg ctgaccgcaa taagggaaca
    27361 gcagcagaag ccaaaattat tgatatccta gaacacagtt tgacaacagt tgtcgggcaa
    27421 atcgttctgg atcaggaaaa gcctaagtat gctggctata ttcgttcaaa aaatcagaaa
    27481 atcagtcaac cgatttatgt taagaaacca gccctaaagt tagaaggaac agaagttctc
    27541 aaagtcttta tcgataaata cccaagcaag aaacatgatt tctttgtcgc gagtgttctc
    27601 gatgtagtgg ggcactcaac ggatgtcgga attgatgttc ttgaggtctt ggaatcaatg
    27661 gacattgtat ctgagtttcc agaagctgtt gtcaaggaag cagaaagtgt gcctgatgct
    27721 ccgtctcaaa aggatatgga aggtcgtctg gatctaagag atgaaattac ctttaccatt
    27781 gacggtgcgg atgccaagga cttggacgat gcagtgcata tcaaggctct gaaaaatggc
    27841 aatctggagc ttggggttca catcgcagat gtttcctatt atgtgaccga gggttctgcc
    27901 cttgacaagg aagcccttaa ccgtgcgact tctgtttacg tgacagaccg agtggtgcca
    27961 atgcttccag aacgactatc aaatggcatc tgctctctca atccccaagt tgaccgcctg
    28021 acccagtctg ctattatgga gattgataaa catggtcgtg tggtcaacta taccattaca
    28081 caaacagtta tcaagaccag ttttcgtatg acctatagcg atgtcaatga tatcctagct
    28141 ggcgatgaag aaaagagaaa agaataccat aaaattgtac caagtatcga actcatggcc
    28201 aagcttcatg aaactttaga aaacatgcgt gtgaaacgtg gagctctcaa ttttgatacc
    28261 aatgaagcga agattttagt ggataaacaa ggtaagcctg ttgatatcgt tcttcggcag
    28321 cgtggcattg ccgagcggat gattgagtct tttatgttga tggctaatga aacagttgcc
    28381 gaacatttca gcaagttgga tttgcctttt atctatcgaa ttcacgagga gcctaaggct
    28441 gaaaaggttc agaagtttat tgattatgct tcgagttttg gcttgcgcat ttatgggact
    28501 gccagtgaga ttagccagga ggcgcttcaa gacatcatgc gtgctgttga gggagaacct
    28561 tatgcagatg tattgtccat gatgcttctt cgctctatgc agcaggctcg ttattcggag
    28621 cacaatcacg gccactatgg actagctgct gactattata ctcactttac cagtccaatt
    28681 cgtcgttatc cagaccttct tgttcaccgt atgattcggg attacggctg ttctaaggaa
    28741 atagcagagc attttgaaca agtgattcca gagattgcga cccagtcttc caaccgtgaa
    28801 cgtcgtgcca tagaagctga gcgtgaagtt gaagccatga aaaaggctga gtatatggaa
    28861 gaatacgtgg gtgaagagta tgatgcagtt gtatcaagta ttgtcaaatt cggtctcttt
    28921 gtcgaattgc caaacacagt tgaaggcttg attcacatca ctaatctacc tgaattttat
    28981 catttcaatg agcgtgattt gactcttcgt ggagaaaaat caggtatcac tttccgagtg
    29041 ggtcagcaga tccgtatccg tgttgaaaga gcggataaaa tgactggaga gattgatttt
    29101 tcattcgtac ctagtgagtt tgatgtgatt gaaaaaggct tgaaacagtc tagtcgtagt
    29161 ggcagagggc gtggttcaaa tcgtcgttcg gataagaagg aagacaagag aaaatcagga
    29221 cgctcaaatg ataagcgtaa gcattcacaa aaagacaaga agaaaaaagg aaagaaacct
    29281 ttttacaagg aagtagctaa gaaaggagcc aagcatggca aagggcgagg gaaaggtcgt
    29341 cgcacaaaat aaaaaggcac gccacgacta tacaatcgta gatacgctag aggcagggat
    29401 ggtcctgact ggaactgaaa tcaagagtgt acgagctgct cgaattaatc tcaaggatgg
    29461 ctttgctcaa gtgaaaaatg gagaagtttg gctgagtaat gttcatatcg cgccttacga
    29521 agagggcaat atctggaacc aggaaccaga acgtcgtcgt aaactcctgc tccataaaaa
    29581 gcaaattcaa aaattggaac aagagaccaa agggacagga atgaccttag ttccccttaa
    29641 ggtctatata aaagatggct acgctaagct tcttttagga cttgccaaag ggaagcatga
    29701 ctatgacaaa cgggagtcta tcaaacgtcg tgagcaaaat cgagatatcg cgcgtgtgat
    29761 gaaagctgtt aatcagcgat aaaaagagga attgaaaatg gaaaaattag ttgcctataa
    29821 acgcatgcct ttgtggaata aacaaacaat gcctgaagct gttcagcaaa agcacaatac
    29881 aaaagttggg acttggggga aaattactgt cttgaaggga gctctcaagt ttattgaatt
    29941 gacagaagaa ggggaagttc tagctgaaca cctctttgaa gcaggggcag acaatccaat
    30001 ggcccaacct caagcctggc accgagtgga agctgccaca gatgatgtgg aatggtactt
    30061 ggaattttat tgtaaacctg aggattattt tgctaaaaaa tacaatacca atcctgttca
    30121 ttcagaggtc ctagaggcca tgcagacagt gaaacaaggg aaagctttgg atttgggttg
    30181 tggtcagggg cgtaattctc tttttctagc ccagcaagat tttgatgtga cggctgtaga
    30241 tcaaaatgga ctagctcttg aaatcttgca aagcattgtg gagcaggaag atttggacat
    30301 gcctgttggc ctttacgata tcaattcagc tagcattgaa caagaatatg attttatcgt
    30361 ttcaacagtt gttctcatgt ttctacaagc ggaccgcatt ccagctatta ttcaaaatat
    30421 gcaggagaaa accagtgttg gtggttacaa ccttatcgtt tgtgccatgg acacggagga
    30481 ttatccttgc tcggttaact tcccattcac ctttaaagaa ggagaactgg cagactatta
    30541 caaggattgg gaattggtta agtacaatga aaatccaggc catttgcacc gtcgcgatga
    30601 gaatggcaat cgtattcaac tacgctttgc gaccttacta gctaagaaaa tcaagtaaac
    30661 acacatgaag attaggaatt ttcctgatct tttttctttt ttacgaatga tatagaaaag
    30721 gagggaattc atgtttgttg cgagagatgc taggggagaa ttggtaaatg tgttagagga
    30781 taaacttgag aagcaagcat acacctgccc agcttgtgga ggccagctcc atttgcgtca
    30841 aggaccaagt gtacggacgc attttgccca taaatcttta aaagactgtg attttttctt
    30901 tgaaaatgaa agtccagaac acctggccaa taaggaatcc ctctatcact ggttgaaaaa
    30961 agagacaaag gttcaattag agtacccgct ttcagaactt aaacagattg cggatgtatt
    31021 tgtaaatggc aatctagctc tagaagttca gtgtagtccc ttgcctcaga aagtccttaa
    31081 agagcgaagt gagggctatc gtagtcaggg ttaccaagta ctgtggttgc tgggtcaaaa
    31141 actgtggctc aaggagcgtt tgactcgtct acagcaaggt tttctttatt tcagtcaaaa
    31201 catgggcttt tatgtttggg aattagacaa gggaaaacaa gttttaagac tcaaatacct
    31261 gatttaccag gatctccgcg gtaaactcca ttatcaaatc aaggaatttt cctatggcca
    31321 aggtagttta ttggaaatat tgcgtcttcc ctataagaaa caaaaaatat ctcattttac
    31381 agtttctgag gacaaggaca tctgtcgcta tatccggcaa caactttatt atcaaaatct
    31441 cttttggatg aaagaacaag cagaagccta tcaaaaggga gaaaatatcc tgacttatgg
    31501 actgaaagaa tggtatccac aaattcgacc aatagtgggc aaatttttcc agattgaaca
    31561 agacttgact agctattatc agcactttta tacctattac caaaaaaatc ctcaaaatga
    31621 ttggcaaaag ctttatccac cagcctttta tcagcaatat ttcttgaaaa atatggtaga
    31681 atagaaagga tggaggaatc taatggtatt acaaagaaat gaaataaatg aaaaagatac
    31741 atgggatcta tcaacgatct acccaactga ccaggcttgg gaagaagcct taaaagattt
    31801 aacagaacaa ttggagacag tagcccagta tgaaggccat ctcttggata gtgcggataa
    31861 cctactagaa atcactgaat tttctcttga aatggaacgc cagatagaga agctttacgt
    31921 ttatgctcat atgaagaatg accaggatac acgtgaagct aagtatcaag agtactatgc
    31981 caaggccatg acactctaca gccagttaga ccaagccttt tcattctatg agcctgaatt
    32041 tatggagatt agcgaaaagc agtatgctga ctttttagaa gctcaaccaa agctgcaggt
    32101 ttatcaacac tattttgaca agctcttgca aggcaaggat cacgttcttt cacaacgtga
    32161 agaagaatta ttggctggag ctggagaaat ctttggttca gcaagtgaaa ccttcgctat
    32221 cttggacaat gcggatattg tgttccctta tgtcctagac gatgatggta aagaagttca
    32281 gctatctcat gggacttaca cacgtttgat ggagtctaaa aaacgtgagg ttcgccgtgg
    32341 tgcctatcaa gctctttatg cgacttacga acaattccaa cacacctatg ccaaaacctt
    32401 gcaaaccaat gttaaggtgc aaaattaccg tgctaaagtt cgtaactaca agagtgctcg
    32461 tcatgcagcc ctcgcagcga attttgttcc agaaagtgtt tatgacaatt tggtagcagc
    32521 agttcgcaag catttgccac tcttacatcg ctatcttgag cttcgttcaa aaatcttggg
    32581 gatttcagat ctcaagatgt acgatgtcta cacaccgctt tcatctgttg aatacaattt
    32641 tacctaccaa gaagccttga aaaaagcaga agatgctttg gcagtcttgg gtgaggatta
    32701 cttgagccgt gtcaaacgtg ccttcagcga gcgttggatt gatgtttacg aaaatcaagg
    32761 caagcgttca ggtgcctact ctggtggttc ttacgatacc aatgccttta tgcttctcaa
    32821 ctggcaggac aatctggaca atctctttac tcttgttcat gaaacaggtc acagtatgca
    32881 ttcaagctat actcgtgaaa ctcagcctta tgtttacgga gattactcta tctttttggc
    32941 tgagattgcc tcaactacca atgaaaatat cttgacggag aaattattgg aagaagtgga
    33001 agacgacgca acacgctttg ctattctcaa taacttccta gatggtttcc gtggaacagt
    33061 tttccgccaa actcaatttg ctgagtttga acacgccatt caccaagcag atcaaaatgg
    33121 ggaggtcttg acaagcgatt tcctaaataa actctacgca gacttgaacc aagagtatta
    33181 tggtttgagt aaggaagaca atcctgaaat ccaatacgag tgggctcgca ttccacactt
    33241 ctactataac tactatgtat atcaatattc aactggcttt gcggccgcct cagccttggc
    33301 tgaaaaaatt gtccatggta gtcaagaaga ccgtgaccgc tatatcgact acctcaaggc
    33361 aggtaagtcg gactatccac ttaatgtcat gagaaaagct ggtgttgata tggagaagga
    33421 agactacctc aacgatgcct ttgcagtctt tgaacgccgt ttaaatgagt ttgaagccct
    33481 tgttgaaaaa ttaggattgg cataaaatgg ttgaatcgta tagtaagaat gctaaccata
    33541 acatgcgtcg tcctgtcgtc aaagaagaaa ttgtagactt gatgcgtcag cgtcaaaagc
    33601 aggtcacagg tttcttgaaa gaattggaag actttgcccg caaggaaaat attcctatta
    33661 ttccccatga aacggttgct tatttccgtt ttcttatgga aaccatgcag cctaaaaata
    33721 ttctggaaat tgggacggct atcggttttt cagctctctt gatggctgaa catgcgccaa
    33781 atgctaagat tacaactatt gatcgtaatc cagaaatgat tggttttgcc aaggaaaatt
    33841 ttgcccagtt tgacagtcgc aagcaaatca ctctcctaga gggagatgcg gttgatgtct
    33901 tatctacact gacagagtct tatgatttcg tctttatgga ttctgccaag tctaaataca
    33961 tcgtctttct gccagaaatc ctcaaacatt tggaagttgg tggtgtggtt gtcttggatg
    34021 atatttttca aggtggtgat gttgccaagg atattatgga agtccgtcgt ggtcagcgaa
    34081 ccatttatcg aggccttcaa aaattatttg atgcaacctt agacaatcca gaactcaccg
    34141 caacattagt gcctttagga gatggtattc tcatgcttcg taaaaatgta gcagatgttc
    34201 aactgtctga aagcgaatga ttttcagaaa aatttaagaa aaaatagtaa aatagataga
    34261 gtaacactta tctcaaagga gtagacatga agaaaaaatt attggcaggt gccatcacac
    34321 tattatcagt agcaacttta gcagcttgtt cgaaagggtc agaaggggca gaccttatca
    34381 gcatgaaagg ggatgtcatc acagaacatc aattttatga gcaagtgaaa aacaaccctt
    34441 cagcccaaca agtcttgtta aatatgacca tccaaaaagt ttttgaaaaa caatatggct
    34501 cagagcttga tgataaagag gttgatgata ctattgccga agaaaaaaaa caatatggcg
    34561 aaaactacca acgtgtcttg tcacaagcag gtatgactct tgaaacacgt aaagctcaaa
    34621 ttcgtacaag taaattagtt gagttggcag ttaagaaggt agcagaagct gaattgacag
    34681 atgaagccta taagaaagcc tttgatgagt acactccaga tgtaacggct caaatcatcc
    34741 gtcttaataa tgaagataag gccaaagaag ttctcgaaaa agccaaggca gaaggtgctg
    34801 attttgctca attagccaaa gataattcaa ctgatgaaaa aacaaaagaa aatggtggag
    34861 aaattacctt tgattctgct tcaacagaag tacctgagca agtcaaaaaa gccgctttcg
    34921 ctttagatgt ggatggtgtt tctgatgtga ttacagcaac tggcacacaa gcctacagta
    34981 gccaatatta cattgtaaaa ctcactaaga aaacagaaaa atcatctaat attgatgact
    35041 acaaagaaaa attaaaaact gttatcttga ctcaaaaaca aaatgattca acatttgttc
    35101 aaagcattat cggaaaagaa ttgcaagcag ccaatatcaa ggttaaggac caagccttcc
    35161 aaaatatctt tacccaatat atcggtggtg gagattcaag ctcaagcagt agtacatcaa
    35221 acgaatagtc caaatcaatg agtcagggaa aaaactcgac ttcaggaaaa aatgaagcaa
    35281 acattcccac aataaaacgc atagtacaag gtttgtactg ccccccaaaa aagttagaca
    35341 attaatttat ccgaaggatt tagttctgta ttgcacagag ctaagtcctt ttagttttat
    35401 cttaattctc ttattgttgt aataatcaat atagtctata atggcttgtt ccaattgatt
    35461 aagtgattta aatgtttgct catagccata aaacatttcg gattttaaaa tgccaaagaa
    35521 agattccatc ctaccgttgt cttggctgtt tcctttgcgt gacatagatg cttgaattcc
    35581 cttactctct aggaagcgat gataagaatc gtgttggtat tgccagcctt ggtcactatg
    35641 gagaatcgta ttctcgtagt gcttctcttt gaatgcctgt tccaacatta acgatcaatc
    35701 aatttaatca tgtacctaag attagaattg tttatcccaa atttatttga aagcttctct
    35761 aagctatatc cttgttttct aagttcatag atctgaactt tatcatcata agttaatttc
    35821 ataataaaaa caccccaaaa gttagatttt ttctgtctaa cttttggggt gtagttcatg
    35881 tacacctgat atgatgcgtt ttataatttt aaagactttt tgaccagcct cattttttaa
    35941 cttgatactc agtgaaaagc aaagattaaa ctaggaagct agctgtaggc tgctcaaaga
    36001 acagctttga ggttgcagat aaaacttgtg aggtaaccaa catatataat gtgaagctga
    36061 cgtggtttga atagatttta ggagggtatg agtctggaag ttttaatgga taatgcaaga
    36121 ttccatagaa tgggtaagct agagttctta tgtgaagagt ttgggcataa acttttacct
    36181 tttcctccct actcatctta gtatagaaaa gtgaatctga aatagtacat aactgcttct
    36241 aaaacattct tataaattga tttaaattct caaatcatat tattcagttc ttatttcatt
    36301 ttgctctaca atcctgttga gaagacacgt gttcatatca aaaaggtatt ggcaagttgc
    36361 aatacctttt tacaaggttc ttttgtctta tttttgtttc aactgactat atctcctatg
    36421 gttctagttc agaaggctag gctataatta tgattgataa gaagtatcat tccaagtatt
    36481 gagagtgaat gtttcaaaat catgggtttc tataatggtc aggctggcat ttgctagacc
    36541 gccatcttta cgaagaagtg gttctttata gcctaggaga gtacgaagac tggcagtaag
    36601 attggcgccg tgtccgacaa ttagaatacg ttcagctgga ctatctttta atgatttgat
    36661 aaattggatg gtccgttgag ttgtactata gagggattcg gctccgaaca ttcgagtgtc
    36721 aaattgagca agatttgaac gaaaagcctg gatttgttgc gggtaaatag cttccaaggt
    36781 tgcaattttc aaaccttcta acttcccaag ttgccattca cggagattag gaacgatttc
    36841 taaagaacag ggggtataga gttgactttg gataatctca gcagatttga ccgctcgagg
    36901 taaatcactt gaataaatct gatcaaaagg aatttccttg agatactgac caagtcgttt
    36961 tagggtttca atggattcag gaagaagagg agaatcacca ctagcacctt gaaaacgacc
    37021 ttcttggttc cagagggtac gaccgtggcg gacaaagtag agtttcatta cttgatgtcc
    37081 tccaaaatat ctacaaagtc tgcctttaca aagctagcca agtcttgtgg cgcgacgata
    37141 atgctgtgtc cgacttcgcc tgcagagaca atcatttgat ccaaatctag agcaatttta
    37201 tcgataaaaa tgggataatt gtgtttctga cgaattccga caggattatt ggctccatga
    37261 atgtaaccag ttgttttttc taagtccttt tgtggaatca tgctcacttt tttattgcca
    37321 gaaattttag ctagtttctt ttcagacaag tgctgagtga tagggacaat tccgataatc
    37381 ggtccggtct tgtctcccaa aagcgccaag gttttgaaaa tctgatctcg ttcataacct
    37441 tgaggaagct ctccttctag ggcattgatt tgaatcccct gatgagggat agctgcttta
    37501 gataggattt gttccaccaa tgtttttttg attttaactt tttttgccat tatttatatt
    37561 tatcctccaa ttgactcatc caaataccaa gccagattcc cagcgcaaag aagaaggcga
    37621 tgatgacata accgacaagt gaaagtcctg tgtattggat actttcagcg tttcctgcat
    37681 ttggaattaa gatcaaaagg gtacttgata ggacgatacc gatgatgaaa tgatagacac
    37741 gtgagtggta gttgtttaag gcataatcca tcaattttga aaaaacgatg agagttgcac
    37801 ctgcaccaat tccaatcgga aagaaggttc ccaagaaatc aaaagtttta aaaccagtca
    37861 acataggagc atagagtccc aaaatcaaaa gtaaatttga tgggctgagg ccaggaacca
    37921 agacgccaag ggccaatagt gcgcctgcta ggacgaagtt aagaaagctg gcgcttaagg
    37981 ttccaacgac aaaatttaag gcatagagtc ctaatccaga aatgataaag gttgtccata
    38041 accaagctaa atcaatcttg tctcggtcag attctcgagt tgattctttg aggaggctag
    38101 gaactgtacc gataatagct cccgcaaagc tccataatac aaaaacctga taattttcaa
    38161 gcaggtattc aatcgggtag gaaaataagc cgattcccag aagcataccg atggcaactg
    38221 gaataaagta caaaacattt tctttaaagt ctttaaaggg atgggccaga aagccaatca
    38281 ttcgttcata gattcctaag attgctgcta gaacccctcc ggaaattccc ggtaggataa
    38341 atccaagagc aattacaatc cctttaataa cgcgtgctaa ccatgagagc atatatttcc
    38401 tccaactatt tctatttcaa aaaatcctta ctatattgta tcacaatcag acacaaaaag
    38461 aaaaagcaaa tgataaacaa atgcttttaa ggttttaaaa aaagttttcg aaaggtttct
    38521 tctttatttt ttaagggaga gataacgttg atatctaaat cgtggtcaaa gccggcaatt
    38581 tttcctttag atgtgtattg gtgaatatca taatctaaat cagttttagg actgctctcc
    38641 aaaaatcctg agtctgagcc gtaggacgga atccaaacag aggtaaactt gcctgtatca
    38701 atactgtgtt cttccatgaa gtagacacca acgtagatgc cgatgttttt agcacctagt
    38761 gatgctagtt ttgctcgaaa gttttcgaca ccttcgttca tattagacat ggttttgtct
    38821 tccacgtcaa gccaatagta actagggctg taaggagagg cagcattgta gaaaacttcg
    38881 gcagcctttt ccatttcttg gacacttttt ccagctacat aagcgtagac agcaactggg
    38941 acattccgct tttgaagttc agtgatatga ctcttatagg tcttgtctat tccattgata
    39001 aatgaagcat cattttcttt tgttgtttga gcaccactgt gaacacgaac aatagcacct
    39061 gaaatatttt gtgagagggc atcgtagttg atttcctcag gacgctgcca gccagagagg
    39121 tcaataatcg gtttgtctaa gtgtttcaaa gcctgtgctt caatctgtgc tatattggat
    39181 tttgttttaa acgattggct gtcattaagt gggcgattga tgattaaaat gaacatcata
    39241 atcccaaaaa aactaaataa aataagtgga tgaatttgtt ttctcatatc ttataattct
    39301 accctaaaaa tcaaaaaaaa tcaaaaaaat gggttaagga agagacttta gagcattttt
    39361 tcattcaaga gtgcggaatg atttgaaata tggtataata aaagggaatt tctacagaaa
    39421 agagaagatt atgtcaaatt ttgccattat tttagcagcg ggtaaaggga ctcgcatgaa
    39481 atctgatttg ccaaaagttt tgcacaaggt tgcgggtatt tctatgttgg aacatgtttt
    39541 ccgtagtgtg ggagctatcc aacctgaaaa gacagtaaca gttgtaggac acaaggcaga
    39601 attggttgag gaggtcttgg ctgaacagac agaatttgtg actcaatctg aacagttggg
    39661 aactggtcat gcagttatga tgacagagcc tatcttagaa ggtttgtcag gacacacctt
    39721 ggtcattgca ggagatactc ctttaatcac tggtgaaagc ttgaaaaact tgattgattt
    39781 ccatatcaat cataaaaatg tggccactat cttgactgct gaaacggata atccttttgg
    39841 ctatggacga attgttcgta atgacaatgc tgaggttctt cgtattgttg agcagaagga
    39901 tgctacagat tttgaaaagc aaatcaagga aatcaacact ggaacatacg tctttgacaa
    39961 cgagcgtttg tttgaggctt tgaaaaatat caataccaat aacgctcaag gcgaatacta
    40021 tattacagac gtcattggta ttttccgtga aactggtgaa aaagttggcg cttatacttt
    40081 gaaagatttt gatgaaagtc ttggggtaaa tgaccgtgtg gcgcttgcga cagctgagtc
    40141 agttatgcgt cgtcgcatca atcataaaca catggtcaac ggtgttagct ttgtcaatcc
    40201 agaagcaact tatatcgata ttgatgttga gattgctccg gaagttcaaa tcgaagccaa
    40261 tgttatcttg aaagggcaaa cgaaaattgg tgctgagact gttttgacaa acggtactta
    40321 tgtagtggac agcactatcg gagcaggagc ggtcattacc aattctatga ttgaggaaag
    40381 tagtgttgca gacggtgtga cagtcggtcc ttatgctcac attcgtccaa attcaagtct
    40441 gggtgcccaa gttcatattg gtaactttgt tgaggtgaaa ggatcttcaa tcggtgagaa
    40501 taccaaggct ggtcatttga cttatatcgg aaactgtgaa gtgggaagca acgttaattt
    40561 cggtgctgga actattacag tcaactatga cggcaaaaac aaatacaaga cagtcattgg
    40621 agacaatgtc tttgttggtt caaattcaac cattattgca ccagtagaac ttggtgacaa
    40681 ttccctcgtt ggtgctggtt caactattac taaagacgtg ccagcagatg ctattgctat
    40741 tggtcgcggt cgtcagatca ataaagacga atatgcaaca cgtcttcctc atcatcctaa
    40801 gaaccagtag gagcctatca tggagtttga agaaaaaacg cttagccgaa aagaaatcta
    40861 tcaaggacca atatttaaac tggtccaaga tcaggttgaa ttaccagaag gcaagggaac
    40921 tgcccaacgg gatttgattt tccacaatgg ggctgtctgt gttttagcag taacggatga
    40981 acaaaaactt atcttggtca agcagtaccg caaagctatc gaggcagtct cttacgaaat
    41041 tccagccgga aaattggagg taggagaaaa cacagcccct gtcgcagctg cccttcgtga
    41101 attagaggaa gaaacagcct atacagggaa attagaactc ttgtacgatt tttattcagc
    41161 tattggcttt tgtaatgaga agttaaaact atatttagca agcgatttga caaaagtgga
    41221 aaatccgcgt ccgcaggatg aggatgaaac cttggaagtc cttgaagtga gcttagaaga
    41281 agcgaaagaa ttaatccaat caggtcatat ctgtgatgcc aagacaatta tggctgttca
    41341 gtattgggag ttgcagaaaa aatagaggag gtcagtatgg gtaaatcttt attaacggat
    41401 gaaatgattg aaagagctaa tagaggcgaa aaaatttcag gtcctccttt gctagatgat
    41461 aatgaggaga ctaagatttt accaacctct tcttcccgtt ttggttatgc caatcctaag
    41521 gatcatggtt ttagccagga aaccttgaaa attcaggtcg aaccatctat tcataaaagc
    41581 cgtcgcattg aaaataccaa gagaaatgtc ttcaattcta agttgaataa aatcttattc
    41641 gcggtcatct ttctcttgat tttgcttgtt ttagcaatga aacttttgta atagaaaagg
    41701 aattgaaatg aaaataggaa ttattgctgc tatgccagaa gaactggctt atctggtcca
    41761 gcatttagat aatacccagg agcaagttgt tttggggaat acctatcata caggaaccat
    41821 tgcttctcat gaagtcgttc ttgtagaaag tggaattggt aaggtcatgt ctgctatgag
    41881 tgtggcgatt ttggctgatc atttccaggt ggatgccctt attaatacgg gttcagctgg
    41941 ggcagtagca gaaggtatcg ctgttgggga tgtcgtgatt gctgacaaat tagcctatca
    42001 tgacgtggat gtcacagctt ttggctatgc ttatggacaa atggcgcaac aaccgcttta
    42061 tttcgaatca gacaaaacct ttgttgctca aatccaagag agtttatctc aattggacca
    42121 aaactggcat cttggtttga ttgctacagg agatagtttt gttgcaggaa atgacaagat
    42181 agaagcgatt aagtcccatt tcccagaagt tttagccgtg gagatggagg gggcagctat
    42241 tgctcaagca gcgcatgccc tcaatctccc agtcttagtc atcagagcta tgagtgacaa
    42301 tgccaaccat gaagcaaaca tcttttttga tgagtttatt atcgaagctg gacgtcgctc
    42361 tgcccaagtc ttgttgacct ttttgaaggc tttagattaa gcggaaattt gacagttttt
    42421 ctagcttatg ataagattta agtaaagaaa agctagaaaa cgtttcagag gatattatga
    42481 gtattgaaat gaccgtcagt gagattgcag aggtcttagg attatctcgc caagcaatca
    42541 ataaccgtgt caaagaatta ccagaagaag acacagataa aaatgacaaa ggggtaacag
    42601 ttgttaccag aagtggcttg attaagctag aagaaatcta taaaaaaacg atttttgaag
    42661 atgagcctgt cagtgaagat gtcaaacaac gtgaactgat ggagattcta gtggatgaga
    42721 agaatgcaga aattcttcgt ctttatgaac aattaaaagc caaggatcgt cagttatcag
    42781 aaaaagacga gcagatgcgt atcaaagacc gtcagattgc tgaaaaagac aaacaattag
    42841 atcagcaaca acaattgacc cttcaagcca tgaaggatca agaaaatctt aagctagagc
    42901 tggaccaagc aaaagaagaa gtccaatcca ctaagaaagg cttttttgct cgtttatttg
    42961 gaggataatc aaggagctgt ttaggttaaa tgctaacctg atggcttctt ttgtttgtga
    43021 atagtatagt tgattagaac agagacagta gaggagaggt acagaatgga acgattagaa
    43081 gattacattg cttttgactt agaatttaat cagcacgaag gacaaacaca cttgattcaa
    43141 gtatcggcag tgcgttttag agatggtcgg gaaatcgatg cctatgattc ctatgttcat
    43201 accagcgtcc ctctaaaaag ctttatcaat ggtttgaccg ggattacagc tgagacctta
    43261 aaagatgctc ctccagttga gaaagtctta gaagaattcc aagagtttgt gggttctttg
    43321 ctgatgatag gctacaatgc tgctaaaagt gatttaccta ttttagcaga gcatggttta
    43381 gactatagcc aacagtacaa ggtggatttg tatgatgaag cttttgaacg tcggagttca
    43441 gatttacatg gtattgcaaa tctcaaattg caaactgttg cctcatttct tggatttcaa
    43501 ggtcagtctc ataatagttt agaggatgct cggatgacgg cgcgtgttta cgaatccttc
    43561 ttagagtcgg atcaagctag ggaattgtta gagacagaaa gtagcttatc aaacaatcct
    43621 tttggtggct tggacttgtc tcaattattt gactaggagt gcctatgaaa cctgaaaaac
    43681 ctaaaaaatt gggtcttaaa cagatttacc tcaatcttga taaaatcctc tttctatttt
    43741 tcttgatttt tatgatagtg gagtatttgt gggtaccatt caattcatgg ttggctagct
    43801 tcttattaga tcagacaggt tatcttttta tttcctataa caatgtctta gccatcctta
    43861 ctcattctcc attgattagt ctagcttttt tagccttgat tgtaattaac cttctggttg
    43921 cttattttca aataggactc ctctttattg gtgctcgtca tctcctctat aatgaaaagc
    43981 gaaggctaat tgagtatatc cgcaaggttt tccatgaaag ttttggattt atgaaaaagc
    44041 taacttgcgc taaagccttg tttatctttt tctatatagc tatgcttttt ccttttatac
    44101 ggaaaatgct gaagatttat tatcttaata aaatcgtcat tccagagttt atccaagctt
    44161 atttagaaga taaatattgg atgtggtggc tgagcatcct acttctatct cttatctttc
    44221 tctatgtctc tgtcagattg atgtttgccc ttccgaagat tgtatatgat cagctgactg
    44281 ttcgagaagc agtgatgttt agcttggaga aaaccaagaa gagagttact ttttatgctt
    44341 ggaatttatt ttacatcttg ctcaaagcac atttattatt ttatcttcct ttgattcctt
    44401 tattattggc tcaaactttg gtagatgata tcactcagag agagtctctg attcttggta
    44461 ttttgaattt tgtcgtgatt aaaaatctct attatatggc tctgacttat tttttggtta
    44521 aatttgtttc atttttgaca ggaaaggagc tggatatgct tcctaggaga gaaaaagatc
    44581 acatcgtgcg atggggtgtc atgacttgtg ccagtctttt ctttgcctta gaaggttata
    44641 tttatctgga ggctcccatg gttcatctac ctcaacttat ttctcaccga ggggtttcca
    44701 atgcaaatgg gattcaaaat acagtagagt ccttggaaac tacagcacaa ctcaaaccag
    44761 acttggtgga gacggacgtg caggaaacaa aagatgggca gtttgtcatg atgcatgatg
    44821 ctaacttgaa aaatctagca ggtatcaata aaagtcctca agacttaaac ttggaggagc
    44881 ttaaagggat tgatattttt gaaaatggct accagactaa aatttcaagc tttgaagatt
    44941 atctcagtcg agccaacgaa cttggtcaaa aattactaat tgaaattaaa accagtaaaa
    45001 aagatagtcc agacatgatg aaccgctttt tagcccgtta tgctgcaaag ctcaagattt
    45061 atggacatca aatccagtct ttagactacc atgttgtcga aaaagtaaga cagtatgatg
    45121 ccgaactgcc agtttatttc atcatgccct acaattctgt ctttcctaaa acaagagcga
    45181 caggatatac tatggagtac tcaaccttgg atgaatattt tgtaagcaaa ctatggacaa
    45241 cggatcagaa actttatgtc tggactgtca atgattcaga agctatcagc aaatctcttc
    45301 acttaggagt agatggagtg attacagatg atttggaaaa agttcagcgg gaaatagaag
    45361 tagcccaaga agatccagaa tatacggatt tgctcttgaa aaaagcattg gaattctttg
    45421 aattttagta ataaaaaaga ggaacggttg ttcctcccat gataggtaag tattcttgtg
    45481 aatgcttgct tttttgtggt tgcaatccgt ttacgagaat tgtttgtatt gttcttgttt
    45541 caatttactt tatagtgctt tgaagttgga atgctacact ataacttcta aaatatagta
    45601 aaatgaacca aaaatagtac acaatgtggt ataatc
//
LOCUS       DAVMJI010000016        45083 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.016, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000016 DAVMJI010000000
VERSION     DAVMJI010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.016"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            115..882
                     /locus_tag="VYR58_001027"
     CDS             115..882
                     /locus_tag="VYR58_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEV3622202.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLNKLVSGSNTLTQKSSRLTAGVG"
     gene            967..1647
                     /locus_tag="VYR58_001028"
     CDS             967..1647
                     /locus_tag="VYR58_001028"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV3622203.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVLVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
     gene            complement(1748..4300)
                     /locus_tag="VYR58_001029"
     CDS             complement(1748..4300)
                     /locus_tag="VYR58_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV3622204.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMGFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIRFHVKLIYIIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(4362..5984)
                     /locus_tag="VYR58_001030"
     CDS             complement(4362..5984)
                     /locus_tag="VYR58_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3622205.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            6190..7215
                     /gene="trpS"
                     /locus_tag="VYR58_001031"
     CDS             6190..7215
                     /gene="trpS"
                     /locus_tag="VYR58_001031"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV3622206.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFTKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            7367..8845
                     /gene="guaB"
                     /locus_tag="VYR58_001032"
     CDS             7367..8845
                     /gene="guaB"
                     /locus_tag="VYR58_001032"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV3622207.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(8896..9993)
                     /gene="recF"
                     /locus_tag="VYR58_001033"
     CDS             complement(8896..9993)
                     /gene="recF"
                     /locus_tag="VYR58_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV3622208.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(9996..10364)
                     /locus_tag="VYR58_001034"
     CDS             complement(9996..10364)
                     /locus_tag="VYR58_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV3622209.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SCRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            10523..11773
                     /locus_tag="VYR58_001035"
     CDS             10523..11773
                     /locus_tag="VYR58_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV3622210.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKGWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            11770..13053
                     /locus_tag="VYR58_001036"
     CDS             11770..13053
                     /locus_tag="VYR58_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV3622211.1"
                     /translation="MTKVVFEKKYYPAVKEMIYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            13095..13916
                     /locus_tag="VYR58_001037"
     CDS             13095..13916
                     /locus_tag="VYR58_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV3622212.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            13927..14472
                     /gene="pgsA"
                     /locus_tag="VYR58_001038"
     CDS             13927..14472
                     /gene="pgsA"
                     /locus_tag="VYR58_001038"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV3622213.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            14469..15296
                     /locus_tag="VYR58_001039"
     CDS             14469..15296
                     /locus_tag="VYR58_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV3622214.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRREWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            15281..16120
                     /locus_tag="VYR58_001040"
     CDS             15281..16120
                     /locus_tag="VYR58_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV3622215.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            16113..16907
                     /locus_tag="VYR58_001041"
     CDS             16113..16907
                     /locus_tag="VYR58_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV3622216.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            16966..17784
                     /gene="mreC"
                     /locus_tag="VYR58_001042"
     CDS             16966..17784
                     /gene="mreC"
                     /locus_tag="VYR58_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV3622217.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            17784..18278
                     /gene="mreD"
                     /locus_tag="VYR58_001043"
     CDS             17784..18278
                     /gene="mreD"
                     /locus_tag="VYR58_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV3622218.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            18372..19550
                     /locus_tag="VYR58_001044"
     CDS             18372..19550
                     /locus_tag="VYR58_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV3622219.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            19774..20553
                     /gene="rpsB"
                     /locus_tag="VYR58_001045"
     CDS             19774..20553
                     /gene="rpsB"
                     /locus_tag="VYR58_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV3622220.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            20632..21672
                     /locus_tag="VYR58_001046"
     CDS             20632..21672
                     /locus_tag="VYR58_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV3622221.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            21919..22242
                     /gene="tnpB"
                     /locus_tag="VYR58_001047"
     CDS             21919..22242
                     /gene="tnpB"
                     /locus_tag="VYR58_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV3622222.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLSYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENVRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
     gene            complement(22397..22705)
                     /locus_tag="VYR58_001048"
                     /pseudo
     CDS             complement(22397..22705)
                     /locus_tag="VYR58_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            22696..23094
                     /locus_tag="VYR58_001049"
     CDS             22696..23094
                     /locus_tag="VYR58_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV3622223.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(23291..24211)
                     /gene="cysK"
                     /locus_tag="VYR58_001050"
     CDS             complement(23291..24211)
                     /gene="cysK"
                     /locus_tag="VYR58_001050"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV3622224.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGCKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(24496..25131)
                     /locus_tag="VYR58_001051"
     CDS             complement(24496..25131)
                     /locus_tag="VYR58_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV3622225.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            25187..26485
                     /locus_tag="VYR58_001052"
     CDS             25187..26485
                     /locus_tag="VYR58_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV3622226.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILAEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            26482..27144
                     /locus_tag="VYR58_001053"
     CDS             26482..27144
                     /locus_tag="VYR58_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV3622227.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            27224..27772
                     /gene="raiA"
                     /locus_tag="VYR58_001054"
     CDS             27224..27772
                     /gene="raiA"
                     /locus_tag="VYR58_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV3622228.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            27908..29881
                     /locus_tag="VYR58_001055"
     CDS             27908..29881
                     /locus_tag="VYR58_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV3622229.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            29878..30330
                     /gene="rplI"
                     /locus_tag="VYR58_001056"
     CDS             29878..30330
                     /gene="rplI"
                     /locus_tag="VYR58_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV3622230.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            30374..31726
                     /gene="dnaB"
                     /locus_tag="VYR58_001057"
     CDS             30374..31726
                     /gene="dnaB"
                     /locus_tag="VYR58_001057"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV3622231.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKRLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            31728..31994
                     /locus_tag="VYR58_001058"
     CDS             31728..31994
                     /locus_tag="VYR58_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622232.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            32083..33429
                     /gene="cbpD"
                     /locus_tag="VYR58_001059"
     CDS             32083..33429
                     /gene="cbpD"
                     /locus_tag="VYR58_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV3622233.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      33512..33614
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            33685..33975
                     /locus_tag="VYR58_001060"
     CDS             33685..33975
                     /locus_tag="VYR58_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV3622234.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            33938..34696
                     /locus_tag="VYR58_001061"
     CDS             33938..34696
                     /locus_tag="VYR58_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622235.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            34734..35741
                     /locus_tag="VYR58_001062"
     CDS             34734..35741
                     /locus_tag="VYR58_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV3622236.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            35741..36469
                     /locus_tag="VYR58_001063"
     CDS             35741..36469
                     /locus_tag="VYR58_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622237.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AETISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            36588..37046
                     /locus_tag="VYR58_001064"
     CDS             36588..37046
                     /locus_tag="VYR58_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV3622238.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLVSVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            37048..39480
                     /locus_tag="VYR58_001065"
     CDS             37048..39480
                     /locus_tag="VYR58_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV3622239.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLMTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            40122..40775
                     /gene="rr06"
                     /locus_tag="VYR58_001066"
     CDS             40122..40775
                     /gene="rr06"
                     /locus_tag="VYR58_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV3622240.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            40772..42103
                     /gene="hk06"
                     /locus_tag="VYR58_001067"
     CDS             40772..42103
                     /gene="hk06"
                     /locus_tag="VYR58_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV3622241.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDENGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVSNILESYQMDYSFLPYEHGMEFKISL"
     gene            42198..42725
                     /locus_tag="VYR58_001068"
     CDS             42198..42725
                     /locus_tag="VYR58_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV3622242.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            42804..>45083
                     /locus_tag="VYR58_001069"
     CDS             42804..>45083
                     /locus_tag="VYR58_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEV3622243.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGIT
                     QVATSYNKANESQTEHRKAAKQVDEDIKKMLSEIQEYIKKMLSEIQLDKRKHTQNVNL
                     NRKLSAIQTKYLYELRVLKEKSKKEELTSKTKKELDAAFEKFKKEPELTKKLAEAKQK
                     AKAQKEEDFRNYPTNTYKTLELEIAEFDVKVKEAELELVKEEAKPRNEEKIKQAKAKV
                     ESKKAEATRLEEIKTERKKAEEEAKRKAEESEKKAAEAKQKVDTKEQGKPKRRAKRGV
                     SGELATPDKKENDAKSSDSSVGEETLPSPSLNMANESQTEHRKDVDEYIKKMLSEIQL
                     DRRKHTQNVNLNIKLSAIKTKYLYELSVLKENSKKEELTSKTKAELTAAFEQFKKDTL
                     KPEKKVAEAEKKVEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELELV
                     KEEANESRNEEKIKQAKEKVESKKAEATRLEKIKTDRKKAEEEAKRKAEESEKKAAEA
                     KQKVDAEEYALEAKIAELEYEVQRLEKELKEIDESDSEDYLKEGLRAPLQSKLDTKKA
                     KLSKLEELSDKIDELDAEIAKLEVQLKDAEGNNNVEAYFKEGLEKTTAEKKAELEKAE
                     ADLKKAVDEPETPAPAPQPAPAPEKPAEKPAPAPAPEKPAPAPQPAPAPEKPAEKPAP
                     APAPEKPAPTPETPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGW
                     LQNNGSWYYLNSNGAMATGW"
BASE COUNT        14406 a         7358 c         9675 g        13644 t
ORIGIN      
        1 attttttaat gtataatcta ttatatcaaa attttagaca atatgtttaa aaaaggagaa
       61 actaagttta aagaatggaa agcaatttaa aaaaaaccaa cctttattat tgtcatgatc
      121 gggatttctc ttattccaga tctgtacaat atcatatttt tgtcatcaat gtgggatcca
      181 tatgggcaat tgtctgactt acctgtggca gttgtaaata atgataaaga ggcttcctat
      241 aatggtaata ctatggcaat aggaaaagac atggtgtcca atttaaaaga aaataaaacc
      301 ttggattttc attttgtaga tgaagaggaa ggaaagaagg gattggaaga tggcgattac
      361 tatatggtag tgactttacc aagtgattta tctgaaaaaa caactacatt atccaatatt
      421 caatcgacag cagcttatca atcattgaca agtgagcaac aaactgagat aagtgattct
      481 gtatctcaaa attcaactga tagtattcaa tcggctcagt caattgtagc tttagtacaa
      541 gatttacagg gaagtttaga aaacttacaa aatcaatctt ctaatctttc gactttaaaa
      601 aatcaatcta atcaagtatc acctattact tctacttctt tgataggatt gtcaagtgga
      661 ttaacagaga tacaaggaga tgttactagc aaattagttc ctgccagtca gtcgattgca
      721 tcaggtgtaa acgcatatac tacaggtgtt gataaagttt ctcagggcgc aagtcaacta
      781 agtgaaaaaa atgccacctt gacaggtagt ttgaataaac tagtttcagg ctcaaacacc
      841 ttgacacaaa aatcttctag attgacagca ggagttggtt aattacaatc aggatctggg
      901 taattagcag acaaatccag tcagttactt tcaggtgctt ctccattaga gaatagagct
      961 aataaattgg cagatggatc tgggaaacta gcagaaggtg gaacaaagtt aacttctgga
     1021 ttggaagatt tacagacagg acttgcttct ttaggacaag gactaggtaa tgctagtgat
     1081 caactcaaat cagtatcaac agaatctaaa aatgcagaga ttttgtcaaa tccactcaat
     1141 ctttcaaaaa cagacaatga tcaagttctt gtaaatggaa tcgcaatagc tccttatatg
     1201 atatcagttg ctctttttgt tgcagcaata tcaacaaata tgatatttgc gaaattgcct
     1261 tcaggacgtc atccagagag ccgttgggct tggttgaaat ctcgagctga aataaatggt
     1321 attatagctg ttttggcagg aattttggta tatggaggag ttcagcttat tggtttaact
     1381 gctaatcatg agatgagaat atttattctc atcatcctaa caagtttagt attcatgtct
     1441 atggtgacca ctttaacaac gtggaatagc cgtataggag cttttttctc acttattttg
     1501 cttttactac agttagcatc aagtgcaggt acttatccac ttgctttgac aaatgatttc
     1561 tttagatcta ttaatccctg gttaccaatg agctattcag tttcgggatt acgacaaaca
     1621 atctccatca acaagtcatt ttcctagctg tcatactagc tctatttact ggtttaggta
     1681 tgctagccta tcaacataag aaaatagaag aagattaaaa aaatcgaccg attaactggt
     1741 cgatttttta tgccttagat gactttcgtc tgtgattata gattccaaat agtaagagag
     1801 aagtaaagga acagattgct ccagtaataa aaccattggg aatgaaggaa agtgtaatag
     1861 ttcctttccc cttgggaatg tcaactttca taaatccagt ttgagcttgt ttaatttcta
     1921 ttttcttacc atcttggtag gcagaccaac ctttgtcata aggaatggtg aagaaaatag
     1981 atgtatcttg ttggacatca tatgtagcaa aaaccttgtt tttagaagtt gatactgtga
     2041 caggttgttc tttaattttt tgaattgcct cggtgaaagt tttggtatct aaacgataga
     2101 aggtaggaga ttcaaatgat acttgtgaat ttccagggaa actaacattg atattgaaag
     2161 tttttttctc tttagtatat cctagattaa agaaggagaa gacattatca gttgtaaaag
     2221 tctttttttc accatttaca aggatgtcaa ccttcttttg tttatcgtta gaaaagtgaa
     2281 ggtttatgaa agagagataa acttggctgt tttctggaac ttcaatttga tactggattg
     2341 ctgcatcttc atttgaagaa cttgtgacac taatcaaatc attagtattt tctatttttt
     2401 ctgttttttc ataaggtatt ggagaaaaat aatcaaaatt gacgttagca agttgattta
     2461 aaaatgaggc ctgattatcc aaggtatgtt cattgaactt gacatcattg taaacagatt
     2521 gactagcaac tgcaatcgga agagagtatt gattttcata tagggtaaga ttatcttttt
     2581 gatagatatc tttaaagcca tacttatcaa taggactgtc tgagatattg tactggatac
     2641 caaataaact atcagccaaa atactattat ttgcatatcg gagattgaga ttagtcccag
     2701 aggatttaaa accaagttta tctaaagtag agcttgatga acgatttcga acagatgaaa
     2761 attgagagat tccattgtag ttgaatttca tactgtcatt tcctgtctga gtttgtagtt
     2821 tttcagtacg agtaaattga tttccaatat atgttgagaa agattccata gctgggatat
     2881 ctcgactata agcacttcga gaagcaaatc cccattcctt agcaattccg tccatttgag
     2941 atgaagcatt taaactcatt tcaaccagta taaataaaga gattagaatg gcaaatagat
     3001 tcacagatat aaactttttg ataactgcaa ggagtaaaag agaatagaca accaaaaatt
     3061 caagagtaag cagaatattc aaatctgtta aaaaagaata atgcgatttt agatagatgg
     3121 tagctaaaaa tcctgttact acaagaaaaa gcgaaactaa aaaattccag actttaagtt
     3181 ctttcagacg ctttaagact tctgctgctg tgtaaattaa caaggtagag aaaatccaag
     3241 catagcgatg taaaaacatg tttggagtat gcatgccttg ccaaaataag tcaagagctt
     3301 ctatgtaaaa gcttgcaatt agaaatgcaa agaatattat atatatgagt ttcacgtgaa
     3361 acctaataga tttcagcgta aaaaataaaa tggtcaaaat aaagggaagt agtccaacaa
     3421 aaatcattgg gatggcccca tactttgttg tgtcaaagga accaatgaat tgcttagcaa
     3481 agagatcaag ataccagcta ctttcagttt gaaactttgt aacttcagtc aatttttccc
     3541 catgtgtctg taaatcaaac agagtgggaa gagtcataat caaactagcc ataccagcta
     3601 aaaaggagat aactatgaaa tcaagaacag atgattttcg agtcttaaag tcccacgaaa
     3661 tttgacagag ataccagaaa ataagaaaca atactgtcat atatccaaaa taataatttt
     3721 gaataaataa gattgacaga cttgtaaagt acaataggag tttcttttca gttatcagta
     3781 gatgtaaacc agttataatt aaaggaatca agataaaaac atctagccag gtttttatct
     3841 ctaattgact gacagtgaaa cccatcagag cataggaagt agataaggct agttttaaag
     3901 tctgagggat agattgaaac aatttattca aactaaaaaa ggttgacaga ccaatcaatc
     3961 caaattttaa gagagtggtc agatagacag catctggcat attcgttaga tcaaaaaagt
     4021 aaactagagg cgcgagaaaa ctacccaagt aataactaga tagggcatag aagtttagcc
     4081 ctagaccact tgtaaaggtg taaaacagac tactatttcc atgtaggata tttcgtaagg
     4141 ctacatcaaa aataacgtat tgatgaaagc catctcctaa tagaggagag ttgtcgctat
     4201 tccagtagat accttgagat agatatactc cagacataat cactacagga atgatgaaag
     4261 aaataaaata ggttcgatat gtttttaaaa atgatttcat gttacctcgt agaatgatag
     4321 aaaactcagt tggttaaccc aactgagttt tgaagtttta tttagtcttt ccaaagttct
     4381 ttaacttttg cttgtacttc tgcattttct aggaattcat cgtaggtttc atcgatacgg
     4441 tcaatgacgc catttttaga taagacaatg atatggttag ccaaagtttg aataaattcg
     4501 tggtcatgac tagcaaagat gattgattct ttaaagtttt tcaatccatc attcaagctt
     4561 gagatagatt ccaagtccaa gtgatttgtt ggatcatcaa gtacaaggac atttgatttt
     4621 aagagcatga gttttgaaag catgacacga actttttctc cccctgacaa gacatttaca
     4681 ggtttgttaa cttcatctcc agagaagagc atacggccga ggaaaccacg taggaaagta
     4741 ttgtcatctt cttctttact tgcgaattga cgcaaccagt caagaattga ttctcctcct
     4801 gcaaaatcag ctgagttatc ttttggtagg taagattgac tagttgtaac tccccacttg
     4861 acagttcctt catagtcaat atctcccatg attgcacgaa ttaatgcagt cgtttgaata
     4921 tcattttgtc caataagtgc tgtcttatca tctggacgca agatgaaact aatattatcc
     4981 aagatagttt caccatcaat ctttacagtt agattttcta ctgtcaagag atcattacca
     5041 atctcacgtt ccgctttaaa gttgataaat ggatatttac gactagatgg tacaatctct
     5101 tctagctcaa tcttatcaag cattttctta cgtgatgttg cctgccttga cttagaagca
     5161 ttggcagaga aacgagcaac gaattcttgc aattgtttaa ttttttcttc tgctttagca
     5221 ttacggtctg ctagcaattt agcagcaagc tcagaagatt ccttccagaa gtcgtagttt
     5281 ccgacataga gtttgatttt tccaaagtca aggtcggcca tgtgagtaca aactttgttt
     5341 aagaagtgac ggtcgtggga tactacgata actgtgttat caaagtcaat taagaagtct
     5401 tctaaccaag taatcgattg gatatccaaa ccgttagtag gctcgtccaa gagaagaaca
     5461 tctggtttac caaaaagtgc tttggcgagg agaaccttta ctttttcacc gttggccaat
     5521 tcgctcatgt tttggtagtg taattcttct ggaatgttta ggttttgaag tagttgagag
     5581 gcttcactct ctgcttccca acctccaagt tcggcaaact ctccttcgag ttcggcagca
     5641 cgaaccccgt cctcgtctga gaaatcttcc ttcatgtaga tagcatcttt ctctttcatg
     5701 atgctataaa gtttttcatt tcccatgata acgacatcaa tggcacgttc atcttcgtag
     5761 tcaaagtgat tttgacgaag aacagagaga cgttcatctg gaccaagaga gatgtgacca
     5821 gtagtaggtt cgatatctcc agctaaaatt tttaaaaagg ttgattttcc ggcaccatta
     5881 gcaccgatta atccgtaagt atttccttct gtaaatttga tattgacatc atcaaaaagt
     5941 ttgcgatcac taaaacgtag tgaaacatca gatactgtaa gcaatatttt tctcctatat
     6001 gtgtaatata tttattctac tagaaaatac agaaatattc aaatttttat ttatcaattt
     6061 tgtgtaaatt atatttacag tatcctttac acaaatctgt aaaaagcaag gctgatttat
     6121 tttgataaat tacggttatt tcattaaaaa aatgctataa ttgaaaggac tatatcgaag
     6181 gagaacaaaa tgactaaacc cattatttta acaggagacc gtccaacagg aaaattgcat
     6241 attggacatt atgttggaag tctcaaaaat cgagtattat tacaggaaga ggataagtat
     6301 gatatgtttg tgttcttggc tgaccaacaa gccttgacag atcatgccaa agatcctcaa
     6361 accattgtag agtctatcgg aaatgtggct ttggattatc ttgcagttgg attggatcca
     6421 aataagtcaa ctatttttat tcaaagccag attccagagt tggctgagtt gtctatgtat
     6481 tatatgaatc tagtttcgtt agcacgtttg gagcgaaatc caacagtcaa gacagagatt
     6541 tctcagaaag gatttggaga aagcattccg acaggattct tggtctatcc aatcgctcaa
     6601 gcagctgata tcacagcttt caaggctaat tatgttcctg ttgggacaga tcagaaacca
     6661 atgattgagc aaactcgtga aattgttcgt tcttttaaca atgcatataa ctgtgatgtc
     6721 ttggtagagc cggaaggtat ttatccagaa aatgagagag cagggcgttt gcctggttta
     6781 gatggaaatg ctaaaatgtc taaatcacta aataatggta tttatttagc tgatgatgcg
     6841 gatactttgc gtaaaaaagt aatgagtatg tatacagatc cagatcatat ccgcgttgag
     6901 gatccaggta agattgaggg aaatatggtt ttccattatc tagatgtttt tggtcgtcca
     6961 gaagatgctc aagaaattgc tgatatgaaa gaacgttatc aacgaggtgg tcttggtgat
     7021 gtgaagacca agcgttatct acttgaaata ttagaacgtg aactgggtcc tattcgtgag
     7081 cgccgtattg aatttactaa ggatatggga gaagtttata atatgattca aaaaggtagt
     7141 gaaagagcgc gtgaagttgc gggtcaaacc ctatctgagg taaaaggggc aatgggactt
     7201 cattacttta actaagttta ttttacaaga aactatcttt tctatctcga agaaaagata
     7261 gttttttatt tacccctgta acatttgaca aatttttata gaatggtatg atagatacaa
     7321 tataaaaaga gtcaagctca aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga
     7381 cactaaattt ttgaaaaaag gttttacctt tgatgatgta ttgcttattc cagctgaaag
     7441 tcatgtgttg cctaacgatg cagatttaac aactaaattg gcagataatt tgactttaaa
     7501 tatcccaatt attaccgctg ccatggacac agttacagag agtcaaatgg ccattgctat
     7561 tgctcgtgca ggcggtctcg gagttatcca taaaaacatg tcaattgctc aacaagcaga
     7621 cgaggttcgt aaggtaaaac gttctgaaaa tggagttatt attgatccgt tcttcttgac
     7681 gcctgaacat acaattgctg aagcagatga gcttatgggt cgttaccgca tcagtggtgt
     7741 tccagttgtt gaaacacttg aaaatcgtaa attggttggt attttgacaa accgagatct
     7801 tcgttttatt tcagattata atcaaccaat ttcaaaccat atgactagtg aaaatcttgt
     7861 tactgctcct gtgggtacgg atcttgcaac ggctgagagt attcttcaag agcatcgtat
     7921 tgaaaaactt ccgttggtcg atgaagaagg cagtctttct ggtttgatca ctatcaaaga
     7981 tattgaaaaa gttattgagt ttccaaatgc ggctaaagat gagtttggtc gtcttctagt
     8041 tgcaggtgca gtaggtgtta cttcagatac atttgaacgt gcagaggctc tttttgaggc
     8101 aggagcggat gcgattgtta ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa
     8161 aattgccgag attcgtgctc atttcccaga tcggactttg attgctggaa atattgctac
     8221 tgctgaaggt gcacgtgccc tttatgaagc gggtgtagac gttgttaagg ttggtattgg
     8281 accaggttct atctgtacta ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc
     8341 tatctacgat gctgcagctg ttgcgcgcga atatggtaaa acgattattg ctgacggtgg
     8401 gatcaagtat tctggagata ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct
     8461 tggatctatg tttgctggaa ctgatgaagc tccaggcgaa actgaaatct tccaaggacg
     8521 taaattcaag acttaccgtg gtatgggatc aattgctgct atgaagaaag gttcaagcga
     8581 ccgttatttc caaggttctg tcaatgaagc aaacaagctt gttccagaag gaattgaagg
     8641 tcgtgttgct tataaaggag cggcagctga tattgttttc caaatgattg gtggtattcg
     8701 ctctggtatg ggttactgtg gtgcagctaa ccttaaagaa ctacacgata atgctcaatt
     8761 tattgaaatg tctggtgctg gtttgaaaga aagccatcct catgatgtgc aaattactaa
     8821 tgaggcacca aattattcta tgtaaaaaac aatgaaaaga actccagtga aaacaggagt
     8881 tcttttacaa tgttgtcaat ttccatttac agcagcttta ccatcctgaa tagtgaagat
     8941 acttagattt tctggcagat tttgaagatg gtctaagctt gttgttgtga taaaggtttg
     9001 gattgattga gaaatcgttt ctaataattt taactgtcta gtgttgtcaa gttcactcat
     9061 cacatcgtca agcagtaata taggagattc tgtggtaatg ctttccatta attcgatttc
     9121 tgctaatttt atcgagagga cgagactacg atgttgacct tggcttccga aactagcatc
     9181 catcccattt atataaaaag aaatgtcatc tcgatgagga ccgacaccag tattcttttt
     9241 aaataaatct ctggatctac ttttttctaa agcaattttg aaagattcgg ataagttttg
     9301 tttgtcagtt atattgacag aagattgata ggatattgac aactcttcga tctgattaga
     9361 gagttcaaaa tgtttcttac gcccaaatga ttctagtttt tttatgaaat ctaagcggtg
     9421 attcattaca cgacatccat aatcaactag ctgatcatct aacacagaaa ggaatgtttc
     9481 atctattttt tgagctgatt ttaggtaagt gtttctttgc tttaggatgt ggttataatt
     9541 ggttaagtca gataaataga ttggcttaat ttgcccaagt tccatatcaa tgaattttcg
     9601 tcgaatcgaa ggtgctcctt taattagttg taaatcttca ggagcaaata agacaacatt
     9661 catgtgtcct acataatctg aaaggcgtgc ctgttttaag tgattaactt ttgttacacg
     9721 gcctttttgt gttagttcga tttctagggg aatggatcca gtttttttct gaacgagacc
     9781 tgaaagatga agttgttcct catcaaaatg aatgagattt ttatctgttc gagttcgatg
     9841 actacgcgtt aaggctaaaa aatagatagc ctctaacatg tttgtttttc cttgtgcatt
     9901 acgtcccaaa aagacattca atttaggatt aaagtctatt ttcgtttctt tgtaattacg
     9961 aaaagtcttg agagatagat gttgtagcca catgattatc taccagggaa tcgtggagct
    10021 tgttggcttt taggtgatga agcaggtttc gatttgtctt ttttaactcc cttattcatc
    10081 tttttgacaa gtttagcgat ccgttctttt tcaactttat cagcttggta ttcatcttgt
    10141 tcttcagaag taggttgtgt caacaagatg tcaatgttca tgtcagggat gtcaacttta
    10201 tcgccaatac gaagtttttt tccacgacaa ctctctaatt ccctattaaa gtaaacagaa
    10261 tgttcagaga gaaatgattt aatagctcct ccgctatgtg taattccaag ttctttgagt
    10321 agtgcttgga gggtaataaa ttcttcaaat aatttgtatt ccataattca cctcaatctt
    10381 tggtattata ccatattttc ctaaaaatag tgagagagac agctagaaat gtaagcgatt
    10441 tttatttcaa aagtgttaca gggaacaaga aaatttcagg ttttcgtgat ataatagaag
    10501 tctgtatata aggaggtaaa tcatggagtt agtgcatgga atttcaacac attttatcca
    10561 atcaaaaaag tttaaaacaa acaaaattac cgtgcgtttt accgctccat tatcccttga
    10621 tacgattgca ggtcacatgt tgagtgcaag tatgttagag actgctaatc agatgtaccc
    10681 cacttctcaa gatttgagga gacacttggc cagtctatac ggtacagata tgtcaaccaa
    10741 ttgtttcaga agagggcaaa gccacattat agaattgaca tttacctatg ttcgtgatga
    10801 gtttttaagt aggaaaaacg tgctaacctc tcagattttg gaacttgtaa aagaaactct
    10861 tttttcaccc gcagtagttg ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa
    10921 acaattgcta gcaagtttag cagctgatat ggatgattct ttttattttg cacataaaga
    10981 attggataaa ttgttttttc atgatgaacg tcttcaattg gaatatagtg atttacgaaa
    11041 tcgtatttta gctgaaactc cacaaagttc ttattcttgt ttccaagaat ttttagccaa
    11101 tgatcgaata gatttctttt tcctaggtga ttttaatgag gttgaaattc aaaatgtatt
    11161 agaatcattt ggctttaaag gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta
    11221 ttctaatatc cttcaggaag gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt
    11281 aggttatcat taccgttcta aatatggtga tgaacaacat ttacccatga ttgtaatgaa
    11341 tggtttactt ggtggatttg ctcactctaa gctctttaca aatgtccgtg aaaatgctgg
    11401 attagcttat accatttcaa gtgagcttga tttatttagt ggattcttga ggatgtatgc
    11461 tggtatcaat cgagaaaatc gtaaccaggc tcgtaaaatg atgaataatc aactgcttga
    11521 tttaaaaaaa ggttatttta cagagtttga gttaaatcag accaaggaaa tgattcgttg
    11581 gtcgttgtta ctttctcaag ataatcaatc ttcattgatt gaacgtgctt atcaaaatgc
    11641 cttatttgga aaatcttcag cagactttaa aggttggatt gcaaaactcg agcaagttga
    11701 caaagatgct atttgtagag cagctaataa tgtgaaacta caggcgattt actttatgga
    11761 aggaatagaa tgacaaaggt tgtttttgaa aaaaaatact atccagctgt aaaagaaatg
    11821 atttatcgaa ctcgtttggc caacggattg acagttgctc ttttgcctaa aaaggaattt
    11881 aaagaggttt acgggagtgt cactgtacag tttggttcgg tagatacgtt tgtcacagaa
    11941 gttgacggag atgtaaaaca atatcctgca ggaattgctc attttcttga acataaatta
    12001 tttgagagag aagattctag tgatttgatg tcggctttta cgagtctagg tgcagatagt
    12061 aatgccttta caagctttac aaaaacaaac tatctttttt cagcaacgga ttatttttta
    12121 gaaaatttat atttacttga tgaattggta acatcagcac actttactga agcttccatt
    12181 ctgacagagc aggatattat tcagcaagaa cgagaaatgt accaagatga tccagattcg
    12241 tgtttattct tttcaacttt agcgaatttg tatcctggta cacctttagc aactgatata
    12301 gttggaagtg aggagtccat ttcccaaatc aatctaacta atttgcaaga aaattttaca
    12361 aagttttaca aacctgtaaa catgtctctg tttttagttg gtaattttga tgtggagcga
    12421 gtacaggact attttgaaag caaagaactg aaagattcag attttcagga agtagcaaga
    12481 gaaaagttgt ttttacagcc tgtaaagcca acagatagta tgagaatgga agtatcttct
    12541 cccaaactag cgattggagt tagaggtaag cgagaagttt ctgaagcgga ttgctatcga
    12601 catcatattt tattaaaatt attgtttgca atgatgtttg gttggacttc ggatcgtttt
    12661 caaaaatgtt atgaatcagg taaaattgat gcgtccttat ctctggaagt tgaaataaca
    12721 agtcgctttc attttgtcat gttgacaatg gatacgaaag agccagttgc tttgtctcat
    12781 caatttagga aggctattcg taattttaca aaggatttag atattacaga ggaacattta
    12841 gatattatca aaagagagat gtttggcgaa tttttcagta gcatgaactc tcttgaattt
    12901 attgcaacgc aatatgatgc ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt
    12961 ttacaggaaa ttactttaga ggatgtcctt gatgctggac atcatttaat agatgatggt
    13021 gacatagttg attttacaat attcccatcg tagtaaccta tcataataga cactagaaag
    13081 aagggatgac aagtatgaga aaaaaaacaa ttggagaggt tttacgatta gctagaatca
    13141 atcagggatt gagtttagat gaattgcaga aaaagacaga aatccagtta gatatgttgg
    13201 aagcaatgga agcagacgat ttcgatcaac ttccaagtcc tttttacacg cgttctttct
    13261 tgaaaaaata tgcatgggct gttgagttag atgaccaaat tgttttggat gcttatgatt
    13321 ctgggagtat gattacttat gaggaagtag atgttgatga agatgagttg acaggtcgta
    13381 gacgttcaag taagaaaaag aagaaaaaaa catcattttt acctttattt tattttatcc
    13441 tttttgcttt atcgatttta atttttgtga cttattatgt ttggaactat attcaaactc
    13501 aaccagagga gccttctctt tctaattaca gtgtggttca atcaacaagt tcaactagct
    13561 ctgttcccca ctcctcaagt agtagttctt ctagtataga atcagctata agtgtatcag
    13621 gcgaaggaaa tcatgtagaa atcgcttata agacaagtaa ggaaacagtt aaattgcaat
    13681 tggcagtttc agatgttaca agttgggtca gtgtttcaga aagcgaactt gagggcggtg
    13741 taaccttatc gccaaagaag aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa
    13801 caattacgtt aggtgttgta aaaggtgttg atttgacagt agataatcag actgttgatt
    13861 tatcgaaatt aacagctcag actggacaaa tcactgtaac ctttactaaa aattaaggaa
    13921 aaacgaatga aaaaagaaca aattcccaat ctcttaacaa taggtcgaat tctctttata
    13981 cctattttta tctttatttt aacgatagga aattcgatag agagtcatat agttgcagct
    14041 attatctttg ctgttgccag tattaccgac tatttagatg gatatttagc tcgtaaatgg
    14101 aatgtggtca gtaattttgg taaatttgca gatcctatgg cggataagtt actagttatg
    14161 tcggctttta ttatgttgat tgagttaggt atggctccgg cttggattgt tgcagtgatt
    14221 atctgtcgtg agttagctgt gacaggttta aggcttttat tggttgaaac tggtggaaca
    14281 attttagcag cagcaatgcc tggaaaaatt aaaactttta gtcagatgtt tgccattatt
    14341 ttcttgctat tacattggac tttgcttggt caagttctac tttatgtagc cttatttttc
    14401 actatctact ctggctatga ctatttcaag ggtagtgcct atgtatttaa agggacattt
    14461 ggttcgaaat gaaatcaata attgatgtaa aaaatctttc ttttcgctat aaagaaaatc
    14521 agaactacta cgatgtgaag gatattacgt ttcacgtgaa acgtagagaa tggctttcga
    14581 ttgtagggca taatggtagt ggtaaatcaa cgacggttcg attaattgat ggcttactgg
    14641 aagcagaatc cggagagatt gtaattgatg gccaacgttt gactgaggaa aatgtttgga
    14701 atatacgtcg tcaaatcggt atggtttttc aaaatccaga caatcaattt gttggagcga
    14761 ctgttgaaga tgatgttgct tttggtttgg aaaatcaggg actttctcgt caagaaatga
    14821 aaaagagagt ggaagaagct ctggctttag ttggcatgtt ggactttaaa aagagagagc
    14881 cagcgcgtct atcaggtggc caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa
    14941 gaccagctat tttaatctta gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag
    15001 aacttattgg gacagtaaaa ggaattcgaa aagactatga tatgacggtc atttctatta
    15061 cccatgattt ggaagaagtc gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa
    15121 ttgaatcaac tagtagtcca agggagcttt tctctcgaaa tgatttagat caaattggat
    15181 tagacgatcc ttttgctaat caattaaaaa aatctttgag ccagaatggc tatgatttac
    15241 ctgaaaatta tttgacagaa agtgagctag aggataagct atgggaattg ctctagaaaa
    15301 tgtgaatttt acatatcaag aaggtactcc cttagcttca gcagctttgt cggatgtttc
    15361 tttgacgatt gaagatggct cttatacagc tttaattggg cacacaggta gtggtaaatc
    15421 aactatttta caactcttaa atggtttatt ggtgccaagt caagggagtg tgagggtttt
    15481 tgatacctta atcacctcga cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt
    15541 tggcttggta tttcagtttg ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt
    15601 tgcttttgga ccgcaaaatt ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga
    15661 gaaactggct ctggttggaa ttgatgaatc actttttgat cgtagtccgt ttgagctgtc
    15721 agggggacaa atgagacgtg ttgccattgc aggcatactt gccatggagc cagctatatt
    15781 agtcttagat gagccaacag ctggtctaga tcctctaggg agaaaagagt tgatgaccct
    15841 gttcaaaaaa ctccaccagt cagggatgac catcgtcttg gtaacgcatt tgatggatga
    15901 tgttgctgaa tatgcgaatc aagtctatgt aatggaaaag ggacgtttag taaagggggg
    15961 caaaccaagt gatgtctttc aagacgttgt ttttatggaa gaagttcagt tgggagtacc
    16021 taaaattacg gccttttgta aacgattggc tgatagaggc gtgtcattta aacgattacc
    16081 gattaagata gaggagttca aggagtcgct aaatggatag tatgatttta gggcgttata
    16141 tcccagggga ttcgattgtt caccgattgg atccacgtag caaattgctt gctatgatgc
    16201 tactgatttt gattgtgttt tgggctaata accccttgac gaatctgatt ctttttatag
    16261 cgacagggat atttattgcc ttgtcaggag tatctctttc attttttatt cagggcttga
    16321 agtctatgtt tttcttgatt gccttcacaa ctatttttca actatttttc atttctaatg
    16381 ggaatgtttt atttgagttt tcgtttgtga gaatcacgga ttatgctttg caacaagctg
    16441 ggattatttt ttgtcgcttt gtattgatta ttttcttttc aactttgtta accttaacaa
    16501 ccatgccttt aagtttggca tcagctgtcg aagctttatt agcaccttta aagcgtgtga
    16561 aagttccagt tcatgaaatt ggattgatgc tgtctatgag tttgcgtttt gtcccaacct
    16621 tgatggatga tacgactcgg attatgaatg cacagaaagc tcgtggagtg gattttggag
    16681 aaggaagcat cgttcaaaaa gtaaaggcga tgattcccat tttgattcct ctttttgcga
    16741 caagtttaaa acgtgcagat tccttggcta tcgctatgga agcgcgtggc tatcagggtg
    16801 gaaaaggcag aagtcaatac cgacaattga aatggactct gaaggatacg ctgaccattc
    16861 ttgttattct cgtacttggt tgttgtttat ttttcttaaa atcttagtag ctttcaggaa
    16921 ttgataaaaa gttactgtaa cagtttttga tataaaggta ggaatatgaa ccgttttaaa
    16981 aaatcaaaat atgtcattat tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg
    17041 acgacttatt caagtacaat tgtgacaaaa ttaggagatg gaatctcatt ggttgataga
    17101 gttgtacaaa aaccttttca gtggtttgat tctgtcaaat cagatttggc tcatttgaca
    17161 cgaacatata atgaaaatga aagtttgaag aaacagcttt accaattaga agttaaatca
    17221 aatgaggtgg aaagtttaaa gacagaaaat gaacaactgc gccaattgct tgatatgaag
    17281 tctaaattgc aagccacaaa gactttagca gcagatgtta ttatgcgttc tccggtatct
    17341 tggaagcagg agttgacctt agatgcaggt agatcaaaag gtgcttctga gaacatgtta
    17401 gctattgcaa atggtggctt gattgggagt gtttcaaaag tagaggagaa ctctactata
    17461 gtcaaccttc tgacaaatac ggaaaatgct gataagattt ctgttaaaat tcaacatggc
    17521 tctactacaa tttatggaat tattattggc tatgacaagg aaaatgacgt tcttaaaatt
    17581 agccaattaa atagtaatag cgatattagt gcgggagata aggtgactac tggtggatta
    17641 ggaaacttta acgttgctga tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca
    17701 gactatttga cacgagaagt aactgttaaa ttgagtgcag atactcataa tgtagatgtg
    17761 atagaattag tggggaattc ataatgagac agttgaagcg agttggagta tttttattgc
    17821 ttcctttctt tgttctaatt gacgcccata ttagccagct tctgggctca tttttccccc
    17881 atgtacattt ggctagtcat tttctttttc tatttctctt atttgagacg atagaagtat
    17941 cagagtatct ctacctagtc tattgttttg ttataggctt ggtttatgat gtttactttt
    18001 tccatctaat agggattaca actctcttat ttatcttatt gggagccttc cttcataaat
    18061 tgaatagtgt tattttgttg aatcgttgga caagaatgct agctatgatt gtgctgacat
    18121 tcctgtttga aatgggtagt tatcttttgg cttttatggt agggttgaca gtagatagca
    18181 tgtcgatttt tatagtctat agcttggtac cgacgatgat tttaaatttt ttatggatta
    18241 ctgtttttca atttattttt gaaaaatatt atctataaga acgacatata aatgtaacaa
    18301 aggcgtaata tttattaggc ctttttttgg tatactagta ttgtctttaa aagaaggagt
    18361 atctacgtaa tatgaagaaa aaaatcttag cgtcactttt attaagtaca gtaatggttt
    18421 ctcaagtagc tgttttaaca actgcgcatg cagaaacgac tgatgacaaa attgctgctc
    18481 aagataataa aattagtaac ttaacagcac aacaacaaga agcccaaaaa caagttgacc
    18541 aaattcagga gcaagtatca gctattcaag ctgagcagtc taacttgcaa gctgaaaatg
    18601 atagattaca agcagaatct aagaaactcg agggtgagat tacagaactt tctaaaaaca
    18661 ttgtttctcg taaccaatcg ttggaaaaac aagctcgtag tgctcaaaca aatggagccg
    18721 taactagcta tatcaatacc attgtaaact caaaatcaat tacagaagct atttcacgtg
    18781 ttgctgcaat gagtgaaatc gtatctgcaa acaacaaaat gttagaacaa caaaaggcag
    18841 ataaaaaagc tatttctgaa aaacaagtag caaataatga tgctatcaat actgtaattg
    18901 ctaatcaaca aaaattggct gatgatgctc aagcgttgac tacgaaacag gcagaactaa
    18961 aagctgctga attaagtctt gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc
    19021 tattagagca aaaagcagca gctgaggcag aggctcgtgc agctgcggta gcagaagcag
    19081 cttataaaga aaaacgagct agccaacaac aatcagtact tgcttcagca aacactaact
    19141 taacagctca agtgcaagca gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc
    19201 gtccaacata cagtacaaac gcttcaagtt atccaattgg agaatgtaca tggggagtaa
    19261 aaacattggc accttgggct ggagactact ggggtaatgg agcacagtgg gctacaagtg
    19321 cagcagcagc aggtttccgt acaggttcaa cacctcaagt tggagcaatt gcatgttgga
    19381 atgatggtgg atatggtcac gtagcggttg ttacagctgt tgaatcaaca acacgtatcc
    19441 aagtatcaga atcaaattat gcaggtaatc gtacaattgg aaatcaccgt ggatggttca
    19501 atccaacaac aacttctgaa ggttttgtta catatattta tgcagattaa tttacagagg
    19561 gactcgaata gagccctctt ttcaggtttt accgtgacaa tccctattaa aaattatatc
    19621 aaaatagctt gaaaatattg gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa
    19681 tactcattct tgatgaattg tgaagcagtt gcccttgggt cgttttgcga gttgaagtca
    19741 agaagaggaa aaaaacaaaa aggagaaata ctcatggcag taatttcaat gaaacaactt
    19801 cttgaggctg gtgtacactt tggtcaccaa actcgtcgct ggaatcctaa gatggctaag
    19861 tacatcttta ctgaacgtaa cggaatccac gttatcgact tgcaacaaac tgtaaaatac
    19921 gctgaccaag catacgactt catgcgtgat gcagcagcta acgatgcagt tgtattgttc
    19981 gttggtacta agaaacaagc agctgatgca gttgctgaag aagcagtacg ttcaggtcaa
    20041 tacttcatca accaccgttg gttgggtgga actcttacaa actggggaac aatccaaaaa
    20101 cgtatcgctc gtttgaaaga aattaaacgt atggaagaag atggaacttt cgaagttctt
    20161 cctaagaaag aagttgcact tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggc
    20221 ggtatcgaag atatgcctcg tatcccagat gtgatgtacg tagttgaccc acataaagag
    20281 caaatcgctg ttaaagaagc taaaaaattg ggaatcccag ttgtagcgat ggttgacacc
    20341 aatactgatc cagatgatat cgatgtaatc atcccagcta acgatgacgc tatccgtgct
    20401 gttaaattga tcacagctaa attggctgac gctattatcg aaggacgtca aggtgaggat
    20461 gcagtagcag ttgaagcaga atttgcagct tcagaaactc aagcagattc aattgaagaa
    20521 atcgttgaag ttgtagaagg tgacaacgct taatttatac aaatagtaat tacctaggag
    20581 ggcggggctt agcccggctc tcctattttc aaaaaatata ggagaattaa aatggcagaa
    20641 attacagcta aacttgtaaa agagttgcgt gaaaaatctg gtgccggtgt tatggacgct
    20701 aaaaaagcgc ttgtagaaac agacggtgac atcgaaaaag cgattgaatt gcttcgtgaa
    20761 aaaggtatgg ctaaggcagc taagaaagct gaccgtgttg ctgcagaagg tttgactggt
    20821 gtttatgtta acggtaatgt tgcagcagtt attgaagtaa acgctgaaac tgacttcgtt
    20881 gcaaaaaacg ctcaattcgt tgaattggta aatactacag ctaaagtcat tgctgaagga
    20941 aaacctgcta acaatgaaga agctcttgct ttgataatgc cttcaggtga aactcttgaa
    21001 gctgcatacg tatctgcaac agcaactatc ggagagaaaa tctcattccg tcgctttgca
    21061 ttgattgaaa aaacagacgc acaacacttt ggagcatacc aacataacgg tggacgtatc
    21121 ggtgttattt cagttgttga aggtggagac gaagcacttg ctaaacaatt gtcaatgcac
    21181 atcgcagcga tgaaaccaac agttctttct tacaaagaat tggatgagca attcgttaaa
    21241 gatgagttgg cacaattgaa tcacgttatc gaccaagaca acgaaagccg tgcaatggtc
    21301 aataaaccag ctcttccaca cttgaagtat ggatcaaaag ctcaattaac tgatgatgtt
    21361 attgctcaag ctgaagctga catcaaagct gaattggctg cagaaggcaa accagaaaaa
    21421 atctgggaca aaattattcc aggtaaaatg gatcgcttca tgcttgataa cactaaagtt
    21481 gaccaagctt acacacttct tgcacaagtt tacatcatgg atgacagcaa gacagttgaa
    21541 gcataccttg aatcagttaa cgcttcggta gttgagtttg ctcgctttga agttggtgaa
    21601 ggtatcgaga aagctgcaaa cgacttcgaa gctgaagttg cagctacaat ggcagcagcc
    21661 ttgaataact aataatagaa aggaagcaaa ttgcttcctt ttttgtatag ggcttagatt
    21721 tttcctgaaa ttgttttttc cccagtctca ctcgattaga ataattaaaa caaaaagccc
    21781 tataataagg gctaagggca tttaggagac tatacttcaa attcatagta agcgcgttca
    21841 taacaaggta tctatcctaa ttccccaact tccagtatac tagataaaaa ataattatcg
    21901 gaggaaaggt attgtactat gataattcaa ctaagtgatt taggtcaagt tcaccttgtt
    21961 tgtagcaaga tagatatgag gcagggaata gactcattat cctatgtagt taaaacccac
    22021 tttgaattgg atcctttctc cggtcaagtc tttctctttt gtggtggacg taaagaccgc
    22081 tttaaagccc tttactggga tggtcaagga ttttggctac tatataaacg ctttgagaac
    22141 gtcagactga cttggcccag tacagaaaag gatgtcaaag ctctcacacc tgaacaagta
    22201 gactggctta tgaagggctt ttctatcact ccaaaaatat agtagattga aactagaata
    22261 gtacacctct gcttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttgtc
    22321 ctgttcttat ttcattttac tataaatcca tcagaaagtc gtgatttcta ttgaaatgag
    22381 gactttcttt ttatactcat ctgttttcaa aaagcattct agtccatctc cgattaacga
    22441 tggactttat cacctccttc tccagtcctt gtataacatc ttggagttga ttcatgacat
    22501 cttccaaagt ttgaaaggtt ttattcttaa atccacgttt acgaatctct ttccacactt
    22561 gttcaatggg gttcatctct ggtgtgtatg gaggaataaa tgcaaagcca atattagtcg
    22621 gaatctttaa ggtacttgat ttatgccata tagcattgtc cataacgagt aaaagataat
    22681 catctggata agcttgtgaa atctcctatt cctaaagccc ctttagcgca taactttggc
    22741 tcagcttcta ttatcgctca caccatccat cagaagttta atctgaaggt acccaattat
    22801 cgccaagaag aagattgggc taggatgggt ttaccaatca cacgtaagga aatctctaat
    22861 cggcatatca agacgagtca atactatttg gagccccttt ataacctctt gcgagagaga
    22921 ctattgactc agcccttact tcatgcggat gaaacttctt atagggtgct agagagtgat
    22981 agtcagctga cttactattg gacttttttg tctgggaaag ctgagaaaca agggattacg
    23041 ctttaccatc atgtcctaat cgatttgttc atatcttatt tcaatccatt ataaatagtg
    23101 agaaatatct atcctatctt ctagaatgtc ttccaaacgt ggaaactctc gtaaacaaag
    23161 aggttttaga ggcctattta ccatggacta aagttgtaca agaaaagtgc aaataagaaa
    23221 tctccagatt aggaactatc cgtgagttct ctagtctgga gatttttcaa tagacttcgt
    23281 tattggacgg ttacaattca taaagtgctg tagagagata acgttcaccg ttatctggtg
    23341 ctagggcaag gactttttta cctgtaccta attttttggc aacctcgatg gctccgtaga
    23401 tagctgcagc tgaggaaatc cctacaagga agccttcttt tccaccaatt tcacgtccga
    23461 gtgcaagagc gtcatctgat gttacacgaa cgataccatc ataggcttta gtatcaagtg
    23521 tatcaggaat aaatccagct gagatacctt gaattttgtg aggaccaggt ttttcaccag
    23581 atagaatagc agattcatct gcttctactg caaaaacttg aatgttagaa ttttctgatt
    23641 tgagtgcatg agaaacacca gaaatcgttc caccagtacc tactccagca acaaaggcat
    23701 ctaatccatc tttaccgaaa gcagctagta tctcagctcc tgttgttctt tcgtgtactt
    23761 ctggattagc tggattgtca aattgaagag gaaggaaacc atcacgttca gcagcgattt
    23821 cttgagcctt agcaatagca cctttcattc cctcgctacc aggagttagg acgagttcag
    23881 caccataagc ttggataatt ttacgtcgtt ctacactcat agtttcaggc ataacgatga
    23941 cgactttaca ccctttagca gcacctaccc atgaaagtcc aataccggtg tttccacttg
    24001 ttgcttcaac aatagtagaa ccaagtttca gaataccatc ttgttcagct ttttcaatca
    24061 tgctaagggc aatacggtct tttacagatg aaccaggatt aaatgcttca agctttatat
    24121 agacgtctgc agcaccttct ggcacgatgt tgttaagttt aacaatcggt gtttgaccga
    24181 ttaattcagt aatgttgtta taaatagaca tatgaatacc tctttgtata agatatcttt
    24241 agtataacgc tatccatacc atttgtaaaa tatagaaatc ctatcgaagc gataggattt
    24301 ctatatatca tagatcaaag tcattaattt tcaagtgatt gcgttcagtt aattctagta
    24361 aataggtgtg aaggaaaacg atatcaggtt tcgtttgaat tgcttcattt tctagtatat
    24421 tttggtacgc atctttttat tttgctcgct aaagtagttg tgagaatgtc aacgaaacgc
    24481 tgtattattc attgtttaca ctaagtttac aggaacttca acctctcgta aaccttggtc
    24541 agttaaagtg acttttccat taaaaaactc cacaagtgca gctttaatag tttctttttc
    24601 ttctttatca acataaatca tcgtatcgac ttgatctgta aagtttgtat ccagctccat
    24661 gagatcatgt tctttaagga agttactgta ctcttggtac tgagcataag acatttgaat
    24721 agcaatgcca gcctgttctt ttatttcaat aataccaatt tctttgacag ctaaggcgac
    24781 actgccggcg taagcacgaa ttagtcctcc agcgcctagt ttaataccac caaagtagcg
    24841 tgtcacgacc acacagacat tggtgagatt gtgattttct agtaccccaa gcatgggaac
    24901 accagcagta ccactaggct caccatcatc acttgtacgt ttaatttcac tacgttctcc
    24961 aataataaag gcagagcagt tatgtgtcgc tttgtagtgt tcttttttga tggcagtaat
    25021 gaagtcacga gcctcttctt cgctataaac acgcttggca tggcagataa agcgagattt
    25081 tttgatttct tcttggactt ggccgtcctc tttaattgtc ctaaattcca tgatttaatt
    25141 gtactaaaaa atcatctaaa gtgctagttt ttacgaataa agaagtatga aagtaaattt
    25201 agattatctc ggtcgtttat ttactgagaa tgaattaaca gaagaagaac gtcagttggc
    25261 ggagaaactt ccagcaatga gaaaggagaa ggggaaactt ttctgtcaac gttgtaatag
    25321 cactattcta gcagaatggt atttgcccat cggtgcttac tattgtcgag agtgcttgct
    25381 gatgaagcga gtcagaagtg atcaaacttt atactatttt ccgcaggagg attttccgaa
    25441 gcaagatgtt ctcaaatggc gcggccaatt aactcctttt caagagaagg tgtcagaggg
    25501 actgcttcaa gcagtagaca agcaaaagcc aaccttagtt catgcggtaa caggagctgg
    25561 aaagacagaa atgatttatc aagtagtggc taaagtgatc aatgcgggtg gtgcagtgtg
    25621 tttggctagt cctcgcatag atgtttgttt ggagctgtac aagcgcctgc aacaggattt
    25681 ttcttgcggg atagctttgc tacatggaga atcggaacct tattttcgaa caccactagt
    25741 tgttgcaaca acccatcagt tattgaagtt ttatcaagct tttgatttgc tgatagtgga
    25801 tgaagtagat gcttttcctt atgttgataa tcccacgctt taccatgctg tcaagaatag
    25861 tgtaaaggag aatggattga gaatcttttt aacagcgact tcgaccaatg agttagataa
    25921 aaaggtccgt ttaggagaac taaaaagact gaatttaccg agacggtttc atggaaatcc
    25981 gttgattatt ccaaaaccaa tttggttatc ggattttaat cgctacttag acaagaatcg
    26041 tttgtcacca aagttaaagt cctatattga gaagcagaga aagacagctt atccgttact
    26101 catttttgct tcagaaatta agaaagggga gcagttagaa gaaatcttac aggagcaatt
    26161 tccaaatgag aaaattggct ttgtatcttc tgtaacagag gatcgattag agcaagtaca
    26221 agcttttcga gatggagaac tgacaatact tatcagtacg acaatcttgg agcgtggagt
    26281 taccttccct tgtgtggatg ttttcgtagt agaggccaat catcgtttgt ttaccaagtc
    26341 tagtttgatt cagattggtg gacgagttgg acgaagcatg gatagaccga caggagattt
    26401 gcttttcttc catgatgggt taaatgcttc aatcaagaag gcgattaagg aaattcagat
    26461 gatgaataag gaggctggtc tatgaagtgc ttgttatgtg ggcagactat gaagactgtt
    26521 ttaactttta gtagtctctt acttctgagg aatgatgact cttgtctttg ttcagactgt
    26581 gattctactt ttgaaagaat tggggaagag aactgtccaa attgtatgaa aacagagttg
    26641 tcaacaaagt gtcaagattg tcaactttgg tgtaaagaag gagttgaagt cagtcataga
    26701 gcgattttta cttacaatca agctatgaag gattttttca gtcggtataa gtttgatgga
    26761 gacttcctgt taagaaaagt tttcgcttca tttttaagtg aggagttgaa aaagtacaaa
    26821 gagtatcaat ttgttgtaat tcccctaagt cctgatagat atgctaatag aggatttaat
    26881 caggttgagg gcttggtaga ggcagcaggc tttgagtatc tggatttatt agagaaaaga
    26941 gaagagagag ccagttcttc taaaaatcgt tcagagcgct tggggacaga acttcctttc
    27001 tttattaaaa gtggagtcac tattcctaaa aaaatcctac ttatagatga tatctatact
    27061 acaggagcaa ctataaatcg tgttaagaaa ctgttggaag aagctggtgc taaggatgta
    27121 aaaacatttt cccttgtaag atgaggaaaa aatttgcaaa aatagaatga aagcgttata
    27181 ataaaatcat aaaaacaaaa atgtttagaa agaaggtact catatgatta aatatagtat
    27241 ccgtggtgaa aacctagaag taacagaagc aattcgtgat tatgtagttt ctaaactcga
    27301 aaagatcgaa aagtacttcc aaccagaaca agagttggat gcccgaatta acttaaaagt
    27361 ttatcgtgaa aaaacggcta aagtggaagt aacgattccg cttggatcta ttactctccg
    27421 cgcagaagat gtatctcaag atatgtatgg ttcaattgac cttgtaactg ataaaattga
    27481 acgtcagatt cgtaaaaata aaacaaaaat cgagcgtaaa aataaaaata aggtagcaac
    27541 tggtcaatta tttacagatg ctttggtgga agattcaaat attgtccagt ctaaagttgt
    27601 tcgttcaaaa caaattgatt taaaaccaat ggatttggaa gaagcaattc tacaaatgga
    27661 tttattgggg catgatttct ttatctatgt ggatgttgaa gatcagacaa ccaatgtgat
    27721 ttatcgtcgt gaggatggcg aaattggttt gttagaggtt aaagaatctt aatttcaata
    27781 tgtgtaaagg taggtttact gaattgtaaa ctaccttttt cttataattg atagaattac
    27841 tgattacact tttaaaaagt cgctttttga ggggtattat ggtataatgg gtgccaagag
    27901 gttttgaatg aaaaaatttt atgtaagtcc aatttttcct attctagtag gattgattgc
    27961 gtttggagtc ttatccactt tcattatttt tgttaataat aatctgttga cggttttaat
    28021 tttgtttctt tttgtaggag gctatgtttt tttatttaag aaactgagag tgcattatac
    28081 aaggagtgat gtagaacaga tacagtatgt aaaccaccaa gcggaagaaa gtttgacagc
    28141 tctattggaa cagatgcctg taggtgttat gaaattgaat ttatcttctg gagaggttga
    28201 gtggtttaat ccctatgctg aattgatttt gaccaaggaa gatggtgatt ttgatttaga
    28261 agctgttcaa acgattatca aggcttcagt aggaaatccg tctacttatg ccaagcttgg
    28321 tgagaagcgt tatgctgttc atatggatgc ttcttccggt gttttgtatt ttgtagatgt
    28381 atccagggaa caagccataa cagatgaatt ggtaacaagt agaccagtga ttgggattgt
    28441 ctctgtggat aattatgatg atttggagga tgcaacttct gagtcagata ttagtcaaat
    28501 caatagtttt gtagctaatt ttatatcaga gttttcagaa aaatacatga tgttttctcg
    28561 tcgggtaagt atggatcgat tttatctatt tactgactac acggtgcttg agggcttgat
    28621 gaatgataaa ttttctgtta ttgatgcttt cagagaagag tcgaaacaga gacagttgcc
    28681 cttgacctta agtatgggat tttcttatgg cgatggaaat catgatgaga tagggaaagt
    28741 tgctttgctc aatttgaact tggctgaagt acgtggtggc gaccaggtgg ttgttaagga
    28801 aaacgacgaa acgaaaaatc cagtttattt tggtggtggg tctgctgctt caatcaagcg
    28861 tacacggact cgtacgcgcg ctatgatgac agctatttca gataagattc ggagtgtaga
    28921 tcaggttttt gtagtcggtc acaaaaattt agacatggat gctttgggct ctgctgtagg
    28981 tatgcagttg ttcgccagca atgtgattga aaatagctat gctctttatg atgaagaaca
    29041 aatgtctcca gatattgaac gagctgtttc attcatagaa aaagaaggag ttacgaagtt
    29101 gttgtctgtt aaggatgcaa tggggatggt gaccaatcgt tctttgttga ttcttgtaga
    29161 ccattcaaag acagccttaa cattatcaaa agaattttat gatttattta cccaaaccat
    29221 tgttattgac caccatagaa gggatcagga ttttccagat aatgcggtta ttacttatat
    29281 cgaaagtggt gcaagtagtg ccagtgagtt ggtaacggaa ttgattcagt tccagaattc
    29341 taagaaaaat cgtttgagtc gtatgcaagc aagtgttttg atggctggta tgatgttgga
    29401 tactaaaaat ttcacctcgc gagtaactag tcggacattt gatgttgcta gctatctcag
    29461 aacgcgcgga agtgatagta ttgctatcca ggaaatcgct gcgacagatt ttgaagaata
    29521 tcgtgaggtc aatgaactta ttttacaggg gtgtaaatta ggttcagatg tactaatagc
    29581 agaggctaag gacacgaaat gctatgatac agttgttatt agtaaggcag cagatgccat
    29641 gttagccatg tcaggtattg aagcgagttt tgttcttgcg aagaatacac aaggatttat
    29701 ctctatctca gctcgaagtc gtagtaaact gaatgtacaa cggattatgg aagagttagg
    29761 cggtggaggc cactttaatt tggcagcagc tcaaattaaa gatgtaacct tgtcagaagc
    29821 aggtgaaaaa ctgacagaaa ttgtattaaa tgaaataaag gaaaaggaga aagaagaatg
    29881 aaagtaatct ttttagcaga tgttaaagga aaaggtaaaa aaggcgaaat taaggaagta
    29941 ccaacagggt atgcgcaaaa ctttcttatc aaaaagaatc tagccaaaga agcgactgct
    30001 caagctgtag gtgaacttcg tggtaaacaa aaatcggaag aaaaagctca cgctgagatg
    30061 attgcagaag gaaaagcaat taaagcacaa cttgaagcag aagaaactgt tgtagaattt
    30121 gttgaaaaag ttggtccaga tggtcgtacc tttggttcta ttaccaataa gaagattgca
    30181 gaagaattgc aaaagcaatt tggaattaag attgataaac gtcatattca agtacaagct
    30241 ccgattcgag cggttggttt gattgatgtg ccagtgaaaa tctatcaaga tatcacaagt
    30301 gtaatcaatc ttcgtgtgaa agaaggataa gtttacacct tcttgacaag attgtaaaag
    30361 gaagggaagt ctgatggcag aagtagaaga gttacgagta caacctcaag atatcttagc
    30421 tgagcaatcc gttttagggg ctatctttat tgatgagagt aaacttgttt ttgtgcgaga
    30481 atacattgag tctcgggact tttttaagta tgcccatcgt ttgattttcc aagccatggt
    30541 cgatttatcc gatcgtggtg atgccataga tgcaacaacg gttcgtacta tccttgataa
    30601 tcaaggtgat ttacagaata ttggtggctt gtcttacttg gttgagattg tcaattctgt
    30661 gccaacttct gctaatgcgg agtattatgc taagattgtt gcagaaaaag caatgctacg
    30721 tcgtttaatt gccaagttga cagagtctgt caaccaagct tacgaagcgt cacaaccagc
    30781 tgatgaaatt attgctcagg cagaaaaaag gttgattgat gtcagtgaaa atgcaaatcg
    30841 aagcgggttt aagaacattc gagatgtgtt gaatctcaac tttggaaatc tggaagctcg
    30901 ctcgcaacaa acgaccgata ttacaggtat tgcgacaggt tatcgtgatt tggatcatat
    30961 gacaacagga cttcatgagg aggagttgat tatcttagca gctcgtccag cagttggtaa
    31021 gacagcattt gccttgaata tcgctcagaa cattgggact aagttggaca aaacggttgc
    31081 tattttttca ctcgaaatgg gtgcggaaag cttggtagat cgtatgttag ctgcagaagg
    31141 cttagtggag tcacattcta tccgtacagg gcaattgaca gatgaggagt ggcaaaaata
    31201 tactattgct cagggtaatc tagctaacgc cagtatctat atcgatgata cgccaggtat
    31261 tcggattaca gagattcgtt ctcgttctcg taaattggct caagaaactg gaaatcttgg
    31321 tttgattttg atagactatt tgcaacttat cacgggaact ggtcgagaaa atcgtcaaca
    31381 agaagtttct gaaatttctc gtcagttgaa aatactagcc aaggaattga aggttccagt
    31441 aatcgctctg agtcagcttt ctcgtggtgt agaacaacgt caggacaaga gaccggtctt
    31501 gtctgatatt cgtgaatctg ggtctattga gcaggacgct gatatcgtag cttttctcta
    31561 tcgcgatgac tactatgaac gtggtggtga agaagaggag ggtatcccaa ataataaggt
    31621 ggaagttatt atcgagaaaa accgtagtgg agctcgtgga acagtggaat tgattttcca
    31681 aaaagaatac aataaatttt caagtatctc aaagagggag gcataagatg tcagatgcat
    31741 ttacagatgt agccaagatg aaaaaaatca aagaagaaat caaggcacat gagggacaag
    31801 tcgtagaaat gactttggag aatggtcgta agcgccaaaa aaatagattg ggtaagctaa
    31861 ttgaagttta tccatctcta tttattgtgg agtttgggga tgtggaagga gataaacaag
    31921 ttaatgttta cgttgaatcc tttacttact cagatattct tacagaaaag aatttgattc
    31981 attatcttga ctaaagtgag aaattttctc actttttctt ttttctccga ataatttagg
    32041 tgaaggcaat catcgcttta tattattttt caaggaggaa gaatgaaaat tttaccgttt
    32101 atagcaagag gaacaagtta ttacttgaag atgtcagtta aaaagcttgt tcctttttta
    32161 gtagtaggat tgatgctagc agctggtgat agtgtctatg cctattccag aggaaatgga
    32221 tcgattgcgc gtggggatga ttatcctgct tattataaaa atgggagcca ggagattgat
    32281 cagtggcgca tgtattctcg tcagtgtact tcttttgtag cctttcgttt gagtaatgtc
    32341 aatggttttg aaattccggc agcttatgga aatgcgaatg aatggggaca tcgtgctcgt
    32401 cgggaaggtt atcgtgtaga taatacaccg acgattggtt ccattacttg gtctactgca
    32461 ggaacttatg gtcatgttgc ctgggtgtca aatgtaatgg gagatcagat tgagattgag
    32521 gaatataact atggttatac agaatcctat aataaacgag ttataaaagc aaacacgatg
    32581 acaggattta ttcattttaa agatttggat ggcggcagtg ttgggaatag tcaatcctca
    32641 gcttcaacag gcggaactca ttattttaag accaagtctg ctattaaaac tgaaccccta
    32701 gctagcggaa ctgtgattga ttactattat cctggggaga aggttcatta tgatcagata
    32761 cttgaaaaag acggctataa gtggttgagt tatactgcct ataatggaag ctatcgttat
    32821 gttcaattgg aggctgtgaa taaaaatcct ctaggtaatt ctgttctttc ttcaacaggt
    32881 ggaactcatt attttaagac caagtctgct atcaaaactg aacccctagt tagtgcaact
    32941 gtgattgatt actattatcc tggggagaag gttcattatg atcagatact tgaaaaagac
    33001 ggctacaagt ggttgagtta tactgcctat aatggaagtc gtcgctatat acagctagag
    33061 ggagtgactt cttcacaaaa ttatcagaat caatcaggaa atatctctag ctatggatcc
    33121 aataatagtt caactgtcgg ttggaagaaa ataaatggta gttggtatca tttcaaatca
    33181 aatggttcta aatcaacagg atggctgaaa gacggttcta gctggtatta tttgaaatta
    33241 tctggtgaaa tgcagacagg atggttaaag gagaatggct cgtggtatta tctgggtagt
    33301 tcaggggcaa tgaaaacagg ctggtaccag gtctctggta agtggtatta ttcttactct
    33361 tcaggcgcct tagctgttaa tacgacggtg gatggctaca gagtaaacag tgatggagaa
    33421 cgagtataga aaattggagt aggagaaatt tcctgctctt ttctgtaagc agtttccttg
    33481 acatttttct tattttgcgc tatcatatat acatataata tatgggagtc tgtgtacagt
    33541 ctgagaggaa gtgttaaact tcgaccgcac ctgatctggg taatgccagc ggagggaacg
    33601 atacttagtc taattttgca ccttttccat gtatggtaaa ggtttttctt ttttttaaaa
    33661 ggaaaacgag aagaggaggt tcttatgaaa gcaagcattg ccttgcaagt tttaccccta
    33721 gcacagggga ttgatcggat agctgttatt gatcaggtca ttgcttatct gcaaactcaa
    33781 gaagtgacga tggtagtgac accatttgaa acggtcttgg aaggggagtt tgatgagctt
    33841 atgcgcattc taaaagaagc gctggaagtg gcagggcagg aggcagacaa tgtctttgcc
    33901 aatgtcaaaa taaatgtagg agagatttta agtattgatg agaaacttga aaagtatact
    33961 gagacgacac attagtctat tgggctttct cggagtattg tcaatctggc agttagcagg
    34021 ttttcttaaa cttctcccca agtttatcct gccgacacct cttgaaattc tccagccctt
    34081 tgttcgtgac agagaatttc tctggcacca tagctgggcg accttgagag tggctttact
    34141 ggggctgatt ttgggagttt tgattgcctg tcttatggct gtgctcatgg atagtttgac
    34201 ttggctcaat gacctgattt accctatgat ggtggtcatt cagaccattc cgaccattgc
    34261 catagctcct atcctggtct tgtggctggg ttatgggatt ttgcccaaga ttgtcttgat
    34321 tatcttaaca acaacctttc ccatcatcgt tagtattttg gacggtttta ggcattgtga
    34381 caaggatatg ctgactttgt ttagtctgat gcgagcaaac ccttggcaaa tcctgtggca
    34441 ttttaaaatc ccggttagcc tgccttactt ttatgcaggt ctgagggtca gtgtctccta
    34501 cgcctttatc acaactgtgg tatctgagtg gttgggaggt tttgaaggtc ttggtgttta
    34561 tatgattcag tctaaaaaac tgtttcagta tgataccatg tttgccatta ttattctggt
    34621 gtcgattatc agtcttttgg gtatgaagct ggtcgatatc agtgaaaaat atgtgattaa
    34681 atggaaacgt acttaaaata gagcgttttt gaaaaagaaa agaggaaatc aaaatgaaga
    34741 aaacatggaa agtgttttta acgcttgtaa cagctcttgt agctgttgtg cttgtggcct
    34801 gtggtcaagg aactgcttct aaagacaaca aagaggcaga acttaagaag gttgacttta
    34861 tcctagactg gacaccaaat accaaccaca cagggcttta tgttgccaag gaaaaaggtt
    34921 atttcaaaga agctggagtg gatgttgatt tgaaattgcc accagaagaa agttcttctg
    34981 acttggttat caacggaaag gcaccatttg cagtgtattt ccaagactac atggctaaga
    35041 aattggaaaa aggagcagga atcactgccg ttgcagctat tgttgaacac aatacatcag
    35101 gaatcatctc tcgtaaatct gataatgtaa gcagtccaaa agacttggtt ggtaagaaat
    35161 atgggacatg gaatgaccca actgaacttg ctatgttgaa aaccttggta gaatctcaag
    35221 gtggagactt tgagaaggtt gaaaaagtac caaataacga ctcaaactca atcacaccga
    35281 ttgccaatgg cgtctttgat actgcttgga tttactacgg ttgggatggt atccttgcta
    35341 aatctcaagg tgtagatgct aacttcatgt acttgaaaga ctatgtcaag gagtttgact
    35401 actattcacc agttatcatc gcaaacaacg actatctgaa agataacaaa gaagaagctc
    35461 gcaaagtcat ccaagccatc aaaaaaggct accaatatgc catggaacat ccagaagaag
    35521 ctgcagatat tctcatcaag aatgcacctg aactcaagga aaaacgtgac tttgtcatcg
    35581 aatctcaaaa atacttgtca aaagaatacg caagcgacaa ggaaaaatgg ggtcaatttg
    35641 acgcagctcg ctggaatgct ttctataaat gggataaaga aaatggtatc cttaaagaag
    35701 acttgacaga caaaggcttc accaacgaat ttgtgaaata atgacagaaa ttagactaga
    35761 gcacgtcagt tatgcctatg gtcaggagag gattttagag gatatcaacc tacaggtgac
    35821 ttcaggcgaa gtggtttcca tcctaggccc aagtggtgtt ggaaagacca ccctctttaa
    35881 tctaatcgct gggattttag aagttcagtc agggagaatt gtccttgatg gtgaagaaaa
    35941 tcccaagggg cgcgtgagtt atatgttgca aaaggatctg ctcttggagc acaagacggt
    36001 gcttggaaat atcattctac ccctcttgat tcaaaaggtg gataaggcag aaactatttc
    36061 ccgagcggat aaaattcttg cgaccttcca gctgacagct gtaagagaca agtatcctca
    36121 tgaacttagc ggtgggatgc gccagcgtgt agccttactc cggacctacc tttttgggca
    36181 taagctcttt ctcttagatg aggcctttag cgccttggat gagatgacaa agatggaact
    36241 ccacgcttgg tatcttgaga ttcacaagca gttgcagcta acaaccctga tcatcacgca
    36301 tagtattgag gaggccctca atctcagcga ccgcatctat atcttgaaaa atcgccctgg
    36361 gcagattgtt tcagaaatta aactagattg gtctgaagat gaggacaagg aagtccaaaa
    36421 gattgcctac aaacgtcaaa tcttggcaga attaggctta gataagtaga aaaataggga
    36481 gttggtgaag attatccttt accagcgccc tttttctttt aaaaatgaga aaatttcggt
    36541 ataatagtca aacaaggtca aggtttaaag agagaggtgg gtttgttatg agatttaaaa
    36601 atacatcgga tcatattgag gcctacatca aggcgatttt agatcaatct ggtatcgtgg
    36661 agttgcaacg gagtcagttg gcagatacct ttcaggttgt tcctagtcag attaactacg
    36721 tgatcaagac acgctttacg gaaagtagag gctacttggt tgaaagtaag cgtggtggcg
    36781 gaggctacat tcgtatagga cggattgagt tttctagtca tcatgaaatg ctccgggagc
    36841 tgctttactc gattggtgag cgagtcagtc aagaaattta tgaggatatt ctccagcttt
    36901 tggttgagca ggaattgatg accaagcagg agatgaattt gctagtatca gtagctttgg
    36961 atcgcgtttt aggagaagaa gctccagttg ttcgagcaaa catgctacgt caggtcatac
    37021 aagaggtaga tagaaaaggg aagtaagatg aactattcaa aagcattgaa tgaatgtatc
    37081 gaaagtgcct acatggttgc tggacatttt ggagctcgtt atctagagtc gtggcacttg
    37141 ttgattgcca tgtctaatca cagttatagt gtagcagggg caactttaaa tgattatccg
    37201 tatgagatgg accgtttaga agaggtggct ttggaactga ctgaaacgga ctatagccag
    37261 gatgaaacct ttacggaatt gccgttctcc cgtcgtttgc aggttctttt tgacgaagca
    37321 gagtatgtag cgtcagtggt ccatgctaag gtgctaggga cagagcacgt cttctatgcg
    37381 attttgcatg atggcaatgc cttggcaact cgtatcttgg agagggctgg tttttcttat
    37441 gaagacaaga aagatcaggt caagattgct gctcttcgtc gaaatttaga agaacgggca
    37501 ggctggactc gtgaagatct caaggcttta cgccaacgcc atcgtacagt agctgacaag
    37561 caaaattcta tggccaatat gatgggcatg ccgcagactc ctagtggtgg tctcgaggat
    37621 tatacgcatg atttgacaga gcaagcgcgt tctggcaagt tagaaccagt catcggtcgg
    37681 gacaaggaaa tctcacgtat gattcaaatc ttgagccgga agactaagaa caaccctgtc
    37741 ttggttgggg atgctggtgt cgggaaaaca gctctggcgc ttggtcttgc ccagcgtatt
    37801 gctagtggtg acgtgcctgc ggaaatggct aagatgcgcg tgttagaact tgatttgatg
    37861 aatgtcgttg cagggacacg cttccgtggt gactttgaag aacgcatgaa taatatcatc
    37921 aaggatattg aagaagatgg ccaagtcatc ctctttatcg atgaactcca caccatcatg
    37981 ggttctggta gcggaattga ttcgactctg gatgcggcca atatcttgaa accagccttg
    38041 gcgcgtggaa ctttgagaac ggttggtgcc accactcagg aagaatatca aaaacatatc
    38101 gaaaaagatg cggctctttc tcgtcgtttc gctaaagtga cgattgaaga accaagtgtg
    38161 gcagatagta tgactatttt acaaggtttg aaggcgactt atgagaaaca tcaccgtgta
    38221 caaatcacag atgaagcggt tgaaacagcg gttaagatgg ctcatcgtta tttaaccagt
    38281 cgtcacttgc cagactctgc tatcgacctc ttggacgaag cagcagcaac agtgcaaaat
    38341 aaggcaaagt atgtaaaagc agacgattca gatttgagtc cagctgacaa ggccctgatg
    38401 gatggcaagt ggaaacaggc agcccagcta atcgcaaaag aagaggaagt acctgtctac
    38461 aaagacttga tgacagagtc tgatattttg accaccttga gtcgcttgtc aggaatccca
    38521 gttcaaaaac tgactcagac tgacgctaag aaatatctaa atcttgaagc agaactccat
    38581 aaacgggtta tcggtcaaga tcaagctgtt tcaagtatta gtcgtgcgat tcgccgtaat
    38641 cagtcaggaa ttcgcagtca caagcgtccg atcggttcct ttatgttcct aggacccaca
    38701 ggtgtcggta agaccgagtt ggccaaggct ttggcagaag ttctctttga tgacgaatca
    38761 gcccttatcc gctttgatat gagtgagtat atggagaaat tcgcagccag ccgtctaaat
    38821 ggagctcctc caggctatgt gggttacgaa gaaggtgggg agttgacaga gaaggttcgc
    38881 aataaaccct attccgttct cctctttgat gaggtagaga aggctcaccc agatatcttt
    38941 aatgttctct tgcaggttct ggatgacggt gtcttgacag atagcaaggg acgcaaggtc
    39001 gatttttcaa ataccattat cattatgaca tcgaatctag gtgcgactgc ccttcgtgat
    39061 gataagactg ttggttttgg ggctaaggat attcgttttg accaggaaaa tatggaaaaa
    39121 cgcatgtttg aagaactgaa aaaagcttat agaccggaat tcatcaaccg tattgatgag
    39181 aaggtggtct tccatagcct atctagtgac catatgcagg aagtggtgaa gattatggtc
    39241 aagcctttag tggcaagttt ggctgaaaaa ggcattgact tgaaattaca agcttcagct
    39301 ctgaaattgt tagcaaatca aggatatgac ccagagatgg gagctcgccc acttcgcaga
    39361 accctgcaaa cagaagtgga ggacaagttg gcagaacttc ttcttaaggg agatttagtg
    39421 gcaggcagca cacttaagat tggtgtcaaa gcaggccagt taaaatttga tattgcataa
    39481 aagaataaaa gtatcagcat ctgaccataa gtcacagtgg agtgaaactc aatgaaaatc
    39541 aaagagcaaa ctaggcagct agccgcaggt tgcttaaaac actgttttga ggttgcagat
    39601 agagctgacg tggtttgaag agattttcga agagtatgaa actaaaacct atagcttcta
    39661 aacgattcgt ggttttcacc attcaacaca aaattcatat gtttattacc ctccgtcgta
    39721 tttgtcttag agcgtgtgta gtagaaaaag agcagtctta tctgaaattt ttattctttc
    39781 aaaagagacc tgtttctttt ttgcatgtca aatccgttct aactggtatt tgaaaaatca
    39841 aactaatact caatgaaaat caaagaacaa actaggcagc tagccgcagg ttgctcaaaa
    39901 cactgttttg aggttgtaga tagagctgac gtggtttgga gagattttcg aagagtataa
    39961 gctgcaagat gaatgatttt cttgtattga cgttgttgtt gacaaaaagt agcggataaa
    40021 tgaaatccat tccattatca tagatgatag gctggtagga aattttcaaa tagcatacag
    40081 gaaatagatg tatggagttc tggtagtaga aagggagaga gatgaacatt ttagttgcag
    40141 atgacgagga aatgattaga gaaggaattg cagcatttct gacagaagag ggttatcatg
    40201 tcattatggc taaggatgga caagaggtct tggaaaaatt tcaagatctc cctatccatc
    40261 tcatggtact ggatttaatg atgcctagga agagtggttt tgaagtgtta aaagaaatca
    40321 atcaaaagca cgatattcct gtcatcgtct tgagtgctct gggagatgaa actactcagt
    40381 cacaggtatt tgatctctat gctgatgatc atgtgacaaa acctttttct ttggtactgc
    40441 ttgtcaagcg tattaaggcg cttatcagac gttactacgt catagaggat atttggcgat
    40501 atcaggatgt aacagtggat tttacctctt acaaagcaca ttataaaaat gaagaaattg
    40561 atctcaaacc aaaggaatta ctggtactaa agtgtttgat tcagcataaa aatcaagttt
    40621 taagtagaga gcagatattg gaagaaattt caaaagatgt agctgattta ccttgtgata
    40681 gggtcgttga tgtctatatt cgtactcttc gcaaaaaatt agctttagat tgtatcgtga
    40741 ctgtgaaaaa tgttgggtat aagattagct tatgataaaa aatcctaaat tattaaccaa
    40801 gtctttttta agaagttttg caattctagg tggtgttggt ctagtcattc atatagctat
    40861 ttatttgacc tttccttttt attatattca actggagggg gaaaagttta atgagagcgc
    40921 aagagtgttt acggagtatt taaagactaa gacatctgat gaaataccaa gcttactcca
    40981 gtcttattca aagtccttga ccatatctgc tcaccttaaa agagatattg tagataagcg
    41041 gctccctctt gtgcatgact tggatattaa agatggaaag ctatcaaatt atatcgtgat
    41101 gttagatatg tctgttagta cagcagatgg taaacaggta acagtgcaat ttgttcacgg
    41161 ggtggatgtc tacaaagaag caaagaatat tttgcttttg tatctcccat atacattttt
    41221 ggttacaatt gctttttcct ttgttttttc ttatttttat actaaacgct tgctcaatcc
    41281 tcttttttac atttcagaag tgactagtaa aatgcaagat ttggatgaca atattcgttt
    41341 tgatgaaagt aggaaagatg aagttggtga agttggaaaa cagattaatg gtatgtatga
    41401 gcacttgttg aaggttattc atgagttgga aagtcgtaat gagcaaattg taaaattgca
    41461 aaatcaaaag gtttcctttg tccgtggagc atcacatgag ttgaaaaccc ctttagccag
    41521 tcttagaatt atcctagaga atatgcagca taatattgga gattacaaag atcatccaaa
    41581 atatattgca aagagtataa ataagattga ccagatgagc cacttattgg aagaagtact
    41641 ggagtcttct aaattccaag agtggacaga gtgtcgtgag accttgactg ttaagccagt
    41701 tttagtagat attttatcac gttatcaaga attagctcat tcaataggtg ttacaattga
    41761 aaatcaattg acagatgcta ccagggtcgt catgagtctt agggcattgg ataaggtttt
    41821 gacaaacctg attagtaatg caattaaata ttcagatgaa aatgggcgcg taatcatatc
    41881 cgagcaagat ggctatctct ctatcaagaa tacatgtgcg cctctaagtg accaagaact
    41941 agaacattta tttgatatat tctatcattc tcaaatcgtg acagataagg atgaaagttc
    42001 cggtttgggt ctttacattg tgagtaatat tttagaaagc tatcaaatgg actatagttt
    42061 tctcccttat gaacacggta tggaatttaa gattagcttg tagacagatt agttttttat
    42121 taaagttcac atagggttaa cataagtgta ttattcttta tatagataaa aatatagata
    42181 aaagaaagga tactaatatg gtattagcga ttattttagt aacattcctt attcgattga
    42241 tttttttaaa gcgttcgata gagaatgaga aacgaatcct tagcaatggc gggaaagaat
    42301 ttggagttga gaatacaaaa cgattaacgt tggctcatat tgttttttat ctctcttgcc
    42361 tcgttgaagc aatggtgcat aagacaatgt ttgatggtat gagcatggtt ggtttagtct
    42421 tgcttatttt ttctatgctg atgttgatgt tggtgattca cttgttggga gatatttgga
    42481 cagtgaagct tatgcttgtc aataatcaca aatatgtaga tcatatcttg tttaggacag
    42541 taaaacatcc taattacttt ttaaatattt tacctgagtt gattggcttg accttgttga
    42601 gtcatgccta tatgactttt gttttagttt ttccagttta tgcagttatt ttgtatcgac
    42661 gaatagctga agaggaaaag ctattacatg aagttataat cccaaatgga agcataaaga
    42721 gataaataca aaattcgatt tatatacagt tcatattgaa gtgatatagt aaggttaaag
    42781 aaaaaatata gaaggaaata aacatgtttg catcaaaaag cgaaagaaaa gtacattatt
    42841 caattcgtaa atttagtatt ggagtagcta gtgtagtagt tgctagtctt gttatgggaa
    42901 gtgtggttca tgcgacggag aatgagggaa ttacccaagt agccacttct tataataagg
    42961 caaatgaaag tcagacagaa cataggaaag ctgctaaaca agtcgatgaa gatataaaaa
    43021 aaatgttgag tgagatccaa gaatatataa aaaaaatgtt gagtgagatc caattagata
    43081 aaagaaaaca tacccaaaat gtcaacttaa acagaaagtt gagcgcaatt caaacgaagt
    43141 atttgtatga attaagagtt ttaaaagaga agtcgaaaaa agaagagttg acgtcaaaaa
    43201 caaaaaaaga gttagacgca gcttttgaga agtttaaaaa agaaccagaa cttactaaaa
    43261 aattagcaga agctaaacaa aaagccaagg ctcaaaaaga agaagatttc cgtaactacc
    43321 caaccaatac ttacaaaacg cttgaacttg aaattgctga gttcgatgtg aaagttaaag
    43381 aagcggagct tgaactagta aaagaggaag ctaaaccccg aaacgaggaa aaaattaagc
    43441 aagcaaaagc gaaagttgag agtaaaaaag ctgaggctac aaggttagaa gaaatcaaga
    43501 cagaacgtaa aaaagcagaa gaagaagcta aacgaaaagc agaagaatct gagaaaaaag
    43561 ctgctgaagc caaacaaaaa gtggatacta aagagcaagg taaaccaaag aggcgggcaa
    43621 aacgaggagt ttctggagag ctagcaacac ctgataaaaa agaaaatgat gcgaagtctt
    43681 cagattctag cgtaggtgaa gaaactcttc caagcccatc ccttaatatg gcaaatgaaa
    43741 gtcagacaga acataggaaa gatgtcgatg aatatataaa aaaaatgttg agtgagatcc
    43801 aattagatag aagaaaacat acccaaaatg tcaacttaaa cataaagttg agcgcaatta
    43861 aaacgaagta tttgtatgaa ttaagtgttt taaaagagaa ctcgaaaaaa gaagagttga
    43921 cgtcaaaaac caaagcagag ttaaccgcag cttttgagca gtttaaaaaa gatacattga
    43981 aaccagaaaa aaaggtagca gaagctgaga agaaggttga agaagctaag aaaaaagcca
    44041 aggatcaaaa agaagaagat cgccgtaact acccaaccaa tacttacaaa acgcttgaac
    44101 ttgaaattgc tgagtccgat gtgaaagtta aagaagcgga gcttgaacta gtaaaagagg
    44161 aagctaacga atctcgaaac gaggaaaaaa ttaagcaagc aaaagagaaa gttgagagta
    44221 aaaaagctga ggctacaagg ttagaaaaaa tcaagacaga tcgtaaaaaa gcagaagaag
    44281 aagctaaacg aaaagcagaa gaatctgaga aaaaagctgc tgaagccaaa caaaaagtgg
    44341 atgctgaaga atatgctctt gaagctaaaa tcgctgagtt ggaatatgaa gttcagagac
    44401 tagaaaaaga gctcaaagag attgatgagt ctgactcaga agattatctt aaagaaggcc
    44461 tccgtgctcc tcttcaatct aaattggata ccaaaaaagc taaactatca aaacttgaag
    44521 agttgagtga taagattgat gagttagacg ctgaaattgc aaaacttgaa gttcaactta
    44581 aagatgctga aggaaacaat aatgtagaag cctactttaa agaaggttta gagaaaacta
    44641 ctgctgagaa aaaagctgaa ttagaaaaag ctgaagctga ccttaagaaa gcagttgatg
    44701 agccagaaac tccagctccg gctcctcaac cagctccagc tccagaaaaa ccagctgaaa
    44761 aaccagctcc agctccagct ccagaaaaac cagctccggc tcctcaacca gctccagctc
    44821 cagaaaaacc agctgaaaaa ccagctccag ctccagctcc agaaaaacca gctccaactc
    44881 cagaaactcc aaaaacaggc tggaaacaag aaaacggtat gtggtacttc tacaatactg
    44941 atggttcaat ggcaacaggc tggctccaaa acaatggctc atggtactac ctcaacagca
    45001 atggcgctat ggcgacagga tggctccaaa acaatggctc atggtactac ctcaacagca
    45061 atggcgctat ggcgacagga tgg
//
LOCUS       DAVMJI010000017        43485 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.017, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000017 DAVMJI010000000
VERSION     DAVMJI010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.017"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            108..3209
                     /locus_tag="VYR58_001070"
     CDS             108..3209
                     /locus_tag="VYR58_001070"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV3622244.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRVAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAIIVPYFDRVESLELGCDYYIGVYPETLASEFHRPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALENLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGFVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYLIDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3292..4299
                     /gene="pfkA"
                     /locus_tag="VYR58_001071"
     CDS             3292..4299
                     /gene="pfkA"
                     /locus_tag="VYR58_001071"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV3622245.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4358..5863
                     /gene="pyk"
                     /locus_tag="VYR58_001072"
     CDS             4358..5863
                     /gene="pyk"
                     /locus_tag="VYR58_001072"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV3622246.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDEVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6597..6822)
                     /locus_tag="VYR58_001073"
                     /pseudo
     CDS             complement(6597..6822)
                     /locus_tag="VYR58_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7670..8542
                     /locus_tag="VYR58_001074"
     CDS             7670..8542
                     /locus_tag="VYR58_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV3622247.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8688..9032)
                     /locus_tag="VYR58_001075"
                     /pseudo
     CDS             complement(8688..9032)
                     /locus_tag="VYR58_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9175..9486
                     /locus_tag="VYR58_001076"
     CDS             9175..9486
                     /locus_tag="VYR58_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622248.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9490..10206
                     /locus_tag="VYR58_001077"
     CDS             9490..10206
                     /locus_tag="VYR58_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV3622249.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10336..11151)
                     /locus_tag="VYR58_001078"
     CDS             complement(10336..11151)
                     /locus_tag="VYR58_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV3622250.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11148..12053)
                     /locus_tag="VYR58_001079"
     CDS             complement(11148..12053)
                     /locus_tag="VYR58_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV3622251.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(12324..12407)
                     /locus_tag="VYR58_001080"
                     /pseudo
     CDS             complement(12324..12407)
                     /locus_tag="VYR58_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            12451..14580
                     /locus_tag="VYR58_001081"
     CDS             12451..14580
                     /locus_tag="VYR58_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV3622252.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            14567..15016
                     /locus_tag="VYR58_001082"
     CDS             14567..15016
                     /locus_tag="VYR58_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV3622253.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            15074..15346
                     /locus_tag="VYR58_001083"
     CDS             15074..15346
                     /locus_tag="VYR58_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV3622254.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(15700..15891)
                     /locus_tag="VYR58_001084"
     CDS             complement(15700..15891)
                     /locus_tag="VYR58_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622255.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFISTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            16319..17077
                     /locus_tag="VYR58_001085"
     CDS             16319..17077
                     /locus_tag="VYR58_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622256.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPTRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSATLLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQLFQEISDTLTVMASEVN"
     gene            17079..19067
                     /locus_tag="VYR58_001086"
     CDS             17079..19067
                     /locus_tag="VYR58_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622257.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(19109..19753)
                     /locus_tag="VYR58_001087"
     CDS             complement(19109..19753)
                     /locus_tag="VYR58_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV3622258.1"
                     /translation="MLRAGVLDANNGIISIAGVVIGVASTTTNIWIIFLSGFAAILAG
                     AFSMAGREYVSVSTPKDTEEAAVLREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     ANKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTRGVTFLLEQLFSI"
     gene            complement(19779..20774)
                     /locus_tag="VYR58_001088"
     CDS             complement(19779..20774)
                     /locus_tag="VYR58_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV3622259.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVIAKGVNVGISTIYYWIHRGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEGVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIHR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLNYKSPREDFLMANLNLKFSVRNKSRN"
     gene            21481..22956
                     /locus_tag="VYR58_001089"
     CDS             21481..22956
                     /locus_tag="VYR58_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV3622260.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSARKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(22922..23512)
                     /locus_tag="VYR58_001090"
     CDS             complement(22922..23512)
                     /locus_tag="VYR58_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV3622261.1"
                     /translation="MSFRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYTPLLIK
                     EFAKSLSLRKTKTNKKDAHGIALKLLSDPNREQFQHDNRQVELKILTRHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTAS
                     NSRAFCRALKSSPNHQIEIRNSLDKTIDFSYSLSFS"
     gene            23893..24753
                     /gene="speE"
                     /locus_tag="VYR58_001091"
     CDS             23893..24753
                     /gene="speE"
                     /locus_tag="VYR58_001091"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV3622262.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            24750..26009
                     /locus_tag="VYR58_001092"
     CDS             24750..26009
                     /locus_tag="VYR58_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV3622263.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            26009..27136
                     /gene="nspC"
                     /locus_tag="VYR58_001093"
     CDS             26009..27136
                     /gene="nspC"
                     /locus_tag="VYR58_001093"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV3622264.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            27133..28218
                     /gene="aguA"
                     /locus_tag="VYR58_001094"
     CDS             27133..28218
                     /gene="aguA"
                     /locus_tag="VYR58_001094"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV3622265.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPVVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVAIDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            28228..29103
                     /gene="aguB"
                     /locus_tag="VYR58_001095"
     CDS             28228..29103
                     /gene="aguB"
                     /locus_tag="VYR58_001095"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV3622266.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(29284..30093)
                     /locus_tag="VYR58_001096"
     CDS             complement(29284..30093)
                     /locus_tag="VYR58_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV3622267.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            30365..30586
                     /locus_tag="VYR58_001097"
     CDS             30365..30586
                     /locus_tag="VYR58_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV3622268.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            30640..31311
                     /locus_tag="VYR58_001098"
     CDS             30640..31311
                     /locus_tag="VYR58_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3622269.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(31363..31560)
                     /locus_tag="VYR58_001099"
                     /pseudo
     CDS             complement(31363..31560)
                     /locus_tag="VYR58_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            31553..32461
                     /locus_tag="VYR58_001100"
     CDS             31553..32461
                     /locus_tag="VYR58_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV3622270.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            32458..32919
                     /locus_tag="VYR58_001101"
     CDS             32458..32919
                     /locus_tag="VYR58_001101"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV3622271.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAILKEEINGN"
     gene            32909..33796
                     /locus_tag="VYR58_001102"
     CDS             32909..33796
                     /locus_tag="VYR58_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV3622272.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            33799..35682
                     /gene="cbpE"
                     /locus_tag="VYR58_001103"
                     /gene_synonym="pce"
     CDS             33799..35682
                     /gene="cbpE"
                     /locus_tag="VYR58_001103"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV3622273.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            35762..36892
                     /locus_tag="VYR58_001104"
     CDS             35762..36892
                     /locus_tag="VYR58_001104"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV3622274.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            36902..38164
                     /locus_tag="VYR58_001105"
     CDS             36902..38164
                     /locus_tag="VYR58_001105"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV3622275.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            38168..38965
                     /gene="proC"
                     /locus_tag="VYR58_001106"
     CDS             38168..38965
                     /gene="proC"
                     /locus_tag="VYR58_001106"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV3622276.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            39185..39823
                     /locus_tag="VYR58_001107"
     CDS             39185..39823
                     /locus_tag="VYR58_001107"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV3622277.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILKEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            39820..40710
                     /locus_tag="VYR58_001108"
     CDS             39820..40710
                     /locus_tag="VYR58_001108"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV3622278.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            40750..41067
                     /gene="yabA"
                     /locus_tag="VYR58_001109"
     CDS             40750..41067
                     /gene="yabA"
                     /locus_tag="VYR58_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV3622279.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            41070..41939
                     /gene="rsmI"
                     /locus_tag="VYR58_001110"
     CDS             41070..41939
                     /gene="rsmI"
                     /locus_tag="VYR58_001110"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV3622280.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKGEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            42166..42684
                     /locus_tag="VYR58_001111"
     CDS             42166..42684
                     /locus_tag="VYR58_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV3622281.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            42793..42930
                     /locus_tag="VYR58_001112"
     CDS             42793..42930
                     /locus_tag="VYR58_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV3622282.1"
                     /translation="MDFEYFYNREAKRFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     K"
     gene            42937..43371
                     /locus_tag="VYR58_001113"
     CDS             42937..43371
                     /locus_tag="VYR58_001113"
                     /inference="COORDINATES: protein motif:HMM:NF018653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV3622283.1"
                     /translation="MSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDIK
                     KGIGLIERVRLGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQ
                     EVKNLDSNYIENNKSKYSKREYSFGENGLGTFQNVFLAAEDI"
BASE COUNT        13175 a         7838 c         9586 g        12886 t
ORIGIN      
        1 aaatgaatag aaaataaatt agtaagctga tgaaattttt ctcaagagaa gccatttata
       61 ggtgaaaatg gtataatata gtgagaagga tagaggagaa gtgtaaattg atcgcacaac
      121 tagatacaaa aacagtctat agttttatgg aaagcgtcat ttcgatcgaa aagtatgtga
      181 gagtagctaa agaatacggc tacactcatt tggctatgat ggatattgac aatctttatg
      241 gcgctttcga ctttctagag attacaaaaa aatacggcat tcatcctttg ctagggcttg
      301 aaatgacagt gtttgtagat gatcagggag tgaatttgcg ctttttagct ctatctagtg
      361 tgggctatca gcagttgatg aagctttcga cagccaagat gcagggggag aaaacttggt
      421 cagtcctgtc ccagtacctg gaggatatcg cgatcattgt gccttatttt gatagagttg
      481 agtcgttaga actaggctgt gattactata taggggttta tccagaaaca ctagcaagcg
      541 aatttcatcg tcctatcttg cccctttatc gggtcaacgc ttttgaaagc agggatagag
      601 aagttcttca agttttaaca gcgattaaag aaaatctacc gctcagagaa gttcccttgc
      661 gttcgagaca agatgtcttt atatcagcaa gttctttaga gaaattattc caagaacgtt
      721 ttcctcaagc cttggaaaac ttagaaaagc ttatttcagg tatttcttac gatttggata
      781 ctagtttgaa actgcctcgt tttaatccag ctagaccagc agtagaggag ttgagagagc
      841 gtgctgaact ggggtttgtt cagaaggggt tgactagtaa agaatatcaa gatagactag
      901 accaagaatt gtctgttatt catgatatgg gctttgatga ttatttcttg gttgtttggg
      961 atttgttgcg ttttggacga tcgaatggct attatatggg aatgggaagg ggttctgcag
     1021 taggcagttt ggtttcttat gccttagaca tcacggggat tgacccagta gagaaaaatc
     1081 tgatttttga acgctttctt aatcgtgaac gctataccat gccagatatt gatattgata
     1141 tcccagatat ttatcgtcca gattttatca gatatgttgg taataaatat ggtagtaaac
     1201 atgcggcaca aatcgttact ttttcaacct ttggagccaa gcaagctcta cgagatgtct
     1261 tgaaacgctt tggtgttcct gagtatgaat tatctgcaat tactaagaaa atcagttttc
     1321 gtgacaatct taagtcggcc tatgagggaa atctccagtt tcgtcagcaa atcaatagta
     1381 agttagaata ccaaaaagct tttgagattg cttgcaagat agagggctat ccaaggcaaa
     1441 cctctgtcca tgcggctggt gttgtaatta gtgaccaaga tttaaccaac tacattcctc
     1501 taaagtatgg tgatgaaatt ccactgactc agtatgatgc tcatggagtt gaggctagcg
     1561 gacttttgaa gatggacttt ctgggactac gaaatttgac ctttgttcag aagatgcaag
     1621 agttgcttgc tgaaacagaa ggtattcatc tgaaaattga agaaatcgat ttagaagaca
     1681 aagaaacgtt agctttattt gcctctggta atacaaaagg tatctttcaa tttgagcaac
     1741 caggtgccat tcgtctgctt aagcgtgtgc aaccagtctg ttttgaagat gtcgtcgcga
     1801 ctacttctct aaatcgaccg ggtgctagtg actatatcaa taattttgtg gcaagaaagc
     1861 atgggcagga agaagtgact gttctggatc cagtactgga ggatattttg gctccaacct
     1921 acggcataat gctctatcag gagcaggtta tgcaggttgc ccagcgactt gccggattta
     1981 gtcttgggaa agccgatatt ttgcgtcggg ctatggggaa aaaggatgcc tctgccatgc
     2041 atgagatgag ggcttccttt attcaaggtt cattagaagc tggtcatact gtggaaaaag
     2101 cagagcaggt ctttgatgtt atggagaagt ttgcaggcta tggttttaac aggtcacacg
     2161 cctatgccta ctcagcattg gccttccagt tggcttattt taaaacacat tatccagcca
     2221 tattttatca gatcatgttg aattctgcca acagtgatta cttaatagat gcacttgaag
     2281 caggttttga agtggcgcct ctgtccatca acacgattcc ctatcacgat aaaattgcca
     2341 acaaggccat ctatctaggt ttgaaatcca ttaaaggagt cagtaatgat ttagctctct
     2401 ggattattga acatagacct tattctaaca ttgaagattt tatagctaaa ttacctgaga
     2461 attatctgaa acttcctctg ctagaacctt tggtaaaagt tggtcttttc gattcatttg
     2521 aaaaaaatcg tcaaaaagta tttaataact tagctaatct atttgaattt gtgaaagagt
     2581 tgggaagttt gtttggagat gctatttata gttggcagga atcggaagat tggacggaac
     2641 aagaaaaatt ttatatggaa caagagcttt tagggatagg tgtcagcaaa catccactac
     2701 aagctattgc aagtaaggct atttacccga ttaccccaat cggaaatttg tcagaaaata
     2761 gctatgctat tattttggtt gaagttcaga aaataaaagt gattcgtacc aaaaagggtg
     2821 aaaatatggc cttcttacag gcagatgata gtaagaaaaa attggatgtc actctctttt
     2881 cagacttata tcgtcaggtt ggacaggaaa taaaagaggg agccttctac tatgtaaaag
     2941 gaaaaataca atcacgtgat ggccgtctgc aaatgattgc acaagaaata agagaagcag
     3001 ttgctgaacg cttttggata caggtgaaaa atcatgaatc ggatcaagaa atttcacgca
     3061 ttttagaaca atttaaaggc ccaatcccag tcatcatccg gtatgaagag gaacagaaaa
     3121 ccatcgtttc tccccatcat tttgtagcta aatccaatga attagaggag aaattgaatg
     3181 aaatcgttat gaaaacgatt tatcgctaaa aatacggaaa atagaagaat tttaaaatca
     3241 aatgtgatat aatcaagaag aatgttaaaa gaaaaaggag cataaaccaa tatgaaacgt
     3301 attgctgttt tgactagtgg cggagacgca cctggtatga acgctgccat ccgtgcagtt
     3361 gttcgtcaag caatttcaga aggaatggaa gtgtttggta tctatgacgg atatgctggt
     3421 atggttgccg gtgaaattca tcccctagat gcagcttcag taggggacat catttctcgt
     3481 ggtggtactt ttcttcactc agctcgttat ccagagttcg ctcaacttga agggcaactt
     3541 aaagggattg agcaattgaa aaaacacgga attgaaggtg tagttgttat cggtggtgac
     3601 ggatcttacc acggcgctat gcgtttgact gaacatggct tcccagctat tggtcttcca
     3661 ggtacaatcg ataacgatat cgttggtact gactttacaa tcggttttga cacagcggtt
     3721 actactgcca tggacgctat cgataagatt cgtgatacat catcaagtca ccgtcgtact
     3781 tttgtaattg aagttatggg acgtaacgct ggtgatatcg ctctttgggc tggtattgca
     3841 actggtgctg atgaaatcat catccctgaa gcaggcttca agatggaaga tatcgtagca
     3901 agcatcaaag ctggttatga atgtggtaaa aaacacaata tcatcgtctt agctgaaggt
     3961 gtgatgtcag cggctgaatt tggtcaaaaa cttaaagaag ctggagatac aagcgacctt
     4021 cgtgtaacag aacttggaca tattcaacgt ggtggttctc caactgcgcg tgaccgtgtt
     4081 ttggcgtcac gtatgggtgc acatgctgtt aaacttctta aagaaggtat cggtggtgtt
     4141 gcggttggta ttcgtaacga aaaaatggtt gaaaatccaa ttcttggtac tgcagaagaa
     4201 ggggcattgt ttagccttac tgcagaaggt aagattgtgg ttaacaaccc gcacaaagcc
     4261 gatattgagc tatctagctt gaataagagc ttgtcataat ttacaattta gttaataaga
     4321 ccaaaaaggt catatatata aaggagtcac aaaaatcatg aacaaacgtg taaagatcgt
     4381 tgcaactttg ggtcctgcgg tagaaatccg tggtggtaaa aaattcggtg aggacggata
     4441 ctggggtgaa aaacttgatg ttgaagcttc agctaaaaac attgctaaat tgattgaagc
     4501 tggtgctaac acattccgat tcaacttctc acacggcgac caccaagaac aaggtgagcg
     4561 tatggcaact gttaaacttg cggaaaaaat tgcaggtaaa aaagttggtt tccttcttga
     4621 tacaaaagga cctgaaatcc gtacagaatt gttcgaaggt gaagctaaag aatattcata
     4681 caaaactggt gaaaaaattc gtgttgcaac taaacaagga atcaaatcaa ctcgtgaagt
     4741 gattgcgttg aacgttgctg gtgctcttga tatctatgat gaagttgaag ttggtcgtca
     4801 agttttggtt gacgatggta aacttggtct tcgtgtggtt gctaaagatg atgcaactcg
     4861 tgaatttgaa gttgaagttg aaaacgatgg tatcatcgct aaacaaaaag gtgtgaacat
     4921 ccctaacact aaaattcctt tcccagctct tgctgaacgc gataacgacg atatccgttt
     4981 cggtcttgaa caaggtatca acttcatcgc aatttcattc gtacgtactg caaaagatgt
     5041 gaacgaagtt cgtgcaatct gtgaagaaac tggaaacgga catgttcaat tgttcgctaa
     5101 aatcgaaaac caacaaggta tcgataactt agatgaaatc atcgaagcag ctgatggtat
     5161 tatgattgct cgtggtgata tgggtatcga agtaccgttc gaaatggttc cagtttatca
     5221 aaaaatgatt atcaagaaag tcaatgctgc aggtaaagtt gttatcactg caacaaacat
     5281 gcttgaaaca atgactgaaa aaccacgtgc aactcgttca gaagtatcag acgtattcaa
     5341 cgctgttatc gacggaactg acgctacaat gttgtcaggc gagtctgcaa acggtaaata
     5401 cccactcgag tcagtaacta caatggctac aatcgacaag aacgctcaag ctcttcttaa
     5461 tgaatacgga cgtcttgatt cagattcatt tgagcgtaac tctaagacag aagtaatggc
     5521 ttctgctgtt aaagatgcta ctagctcaat ggatatcaaa ttggttgtaa ctcttactaa
     5581 gacaggtcat actgcacgtt tgatttctaa ataccgtcca aatgctgaca tcttagcatt
     5641 gacatttgac gaattgacag aacgtggctt gatgttgaac tggggtgtta tcccaatgtt
     5701 gacagatgct ccatcttcaa ctgacgatat gttcgaaatc gctgaacgta aagcggtaga
     5761 agcaggtctc gttgagtcag gcgatgatat cgttatcgtt gctggtgtgc cagtaggaga
     5821 agctgttcgc acaaacacaa tgcgtatccg cacagtacgt taagaaaaat ataaaaacct
     5881 atcatatcca gctttctagc ctgtatgatg ggctcttttt ttgtccaggg ggcaaaaagg
     5941 gggcaaaact ttcataatgg attgatactc ttcgaaaatc tcttcaaacc acgtcagcgt
     6001 cgccttaccg tatatatgtt actgacttcg tcagttctat ctacaacctc aaagcagtgc
     6061 tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga gtatgaaata
     6121 agatatgcat aaattgatta gaaagtcaaa tgaatttcta caaatgtttt agcaatcgca
     6181 atctacttgt ctagattcga tctgatatat tttcgattta atgatatggt atttaaaacc
     6241 tccaaagtag cttgctccat tcttttacct acgtgagtct agatgttatt tactgtttta
     6301 gcgtttttgt gttctactct aaccattata gcattcttct cagctagtgt actaaggagt
     6361 gtgtgcctga aaatatggga actaaggggc tggtttatcg gtttctctag tttagtattt
     6421 gccttttgca aagtgatctt aaatgccttt ctctaaattt acatatcact attgtttaac
     6481 aaaatctaat ctattttagg tcacttattc tttttttgaa atgtagaatg aactttttca
     6541 aagtttttcg aatcttttaa aatctgtttg ttttatatcg ccattctccc ccttttttaa
     6601 ttctccctat atagcctgac aacttttccg atggtacgaa tatggttgct ttcgtctagg
     6661 tggatgtcgg agtattcggg attgagtttt tttgaggtag ccttggcgga gtttcttgac
     6721 atagttagtg ccgtctactt ggaagatgcc gatggtatta tagtcaatct gtggggtatt
     6781 cttgataaat aggtagtcgc tgtttcttat ctttggctcc atggacttgc tgacgacata
     6841 agcgattggg tcgtagtcgt ctgggataat ggaaactcca taactaaatc gtcgtcctgc
     6901 atcaagcggc tacctgcaga gataaactac ctaacacgag agtaagtagt ctgtctgtag
     6961 tcgtccagtc tgatgatttt tacgatactt cgtttttctg atcatacagt tgcctctcgg
     7021 cataggtcag aactttacct tgtctgggtg gtgcccgttg gtcgtagata gattggatat
     7081 cgctaggaga atccttttga actggaggaa agagggcatc aatcaagcta ctgaatactt
     7141 taactaagtc aaatatagta tttttcttag tagacctaac ccttttttca taatttctaa
     7201 tggtgttttt acttatacct atcttagtac ccaattctta ttgagtccaa ccattactag
     7261 tctatattgt tttatagttg attgagtttg gaatagtacg ctgtagctgc taaaacattt
     7321 ctaggaatta atttgccttt cctaatagag ttgttcatat cttatttcaa tctactatat
     7381 ttttcacctc taacaatcgc aatctcttct ttatccatga acgaaaacgc tttctatctt
     7441 tgtaagtaaa gcatcacacg aaatccacga aaatgaaaac ctttgttgtg ttttcgtaaa
     7501 aaatttgttg acagagcacg aaacgcctac tataattaaa tcaagtttaa ggaaataaca
     7561 aaaaaacaaa tcggagggaa agacgatgaa cacattaaat gagaaagtaa tcaatatctg
     7621 taaagcagta gttaaagaaa ctttaatcca agacatttag gagaaagaaa tgaagaaatc
     7681 aagaaaatta gccacattag gaatctgttc agccttgttt ttaggcttgg ctgcttgtca
     7741 acaacaacat gctacttctg aggggacgaa tcaaaggcaa agcagttcag cgaaagttcc
     7801 atggaaagct tcatacacca acctaaacaa ccaggtaagt acagaagagg tcaaatctct
     7861 cttatcagct cacttggatc caaatagtgt tgatgcattt tttaatctcg ttaatgacta
     7921 taataccatt gtcggctcaa ctggcttatc aggagatttc acttccttta ctcacaccga
     7981 atacgatgtt gagaaaatca gtcatctctg gaatcaaaag aagggcgatt tcgttgggac
     8041 caactgccgt atcaatagtt attgtctttt gaaaaattca gtcaccattc caaagcttga
     8101 aaagaatgac cagttgcttt tcctagataa tgatgcgatt gataaaggaa aggtctttga
     8161 ttcacaagat aaggaagagt ttgatattct attttcgaga gttccaactg aggcaactac
     8221 agatgtcaag gttcacgctg aaaagatgga aacattcttc tcacaatttc aattcaatga
     8281 aaaagctcga atgctgtctg tagtcttgca cgacaatctg gatggcgagt atctgtttgt
     8341 aggccacgtt ggggtcttag tacctgctga tgacggtttc ttatttgtag agaaattgac
     8401 tttcgaagag ccctaccaag cgattaaatt tgctagtaag gaagattgct acaagtattt
     8461 gggcaccaag tatgcggatt atacaggcga gggactggct aagcctttta tcatggataa
     8521 tgataagtgg gttaaacttt aatagtgtta tgatatgaca gtaatcttag gatttttatt
     8581 tctatttttg atgacttggt gggttatttc aatcgttaat agccagaaac cacgcaaaaa
     8641 tgaaacattt attggctata tccaaagata cgatattgat gggaatggct atcaatcatt
     8701 accgtgtcct cagaattgag aggagttctt gaaatcgtaa aactactttg aacaagagtt
     8761 acttcaaccc attggctccg acggattaag ttgctttcgt gaacaccaaa atcagccgca
     8821 atttcttcat aagtgcggta ttctcgcaca tattgaagag tggccataag aaggtcttct
     8881 aggcttaatt taggttttcg tccccctttt gtgtgtttaa gttgataagc agtttttaat
     8941 acagctaaca tctcttcaaa agtggtgcgc tgaacaccaa caagacattt aaatcgtgca
     9001 tcagttagtt gcttacttgc ttcataattc atagaactac tataccatat tttgtttcgc
     9061 aggaagtcta atgctaaaat cttatcagtg agaagatttc ttaaagttta ttctttgtag
     9121 tttcatctgt attagtatat aatttaactt agagaaaata ggaggactaa tcgaatggaa
     9181 ttaaaagatt ttacagaaaa agaacaggaa atgattaaga aaaggcttac aatgtctaat
     9241 attagtgaca aagaaactac tgagaagatt ctggcgctag taccacaaga cttgattaag
     9301 cgaatcccgt tttttgtcag aaaacatgct acaacacgta cgattaaacg catttcaatt
     9361 gaataccctg aactctacgc tgtagctcaa acaagtggtg agattccaga aaaagaacgc
     9421 gaagaattgc gtcagattat cacgactatc tttgaacaaa agatgaataa gcatagtatt
     9481 aagtagagaa tgaaaaaata ttttattagc ggtttgggaa gcaatgccta tcatagcaag
     9541 gatttttttc aagaactaga ttcgcaggtc tattttctaa atccatatga aaagcatctt
     9601 cgagatgaaa cagaattgaa atcatggttt aaaaatgaga ttgtagagga agaatctatc
     9661 tgtctgatag gccattctct tggaggagat ttagctcgtt atttcgcatc ggaatttgaa
     9721 gaagtaaaga aactgattct tttggatggt ggctatctag atttagataa gattttacct
     9781 ttggatacag agttagagga aactaaaaat tatatcaaat ctcaaattgt ttcggactta
     9841 gctcttctta tttctaaaga gaagtccgaa gcaaagcatt ggtcagaaaa tatggagaaa
     9901 gctgtaagac agtcctatca ctggaatgtt gagtataata gatatgagtt ggctataaat
     9961 tatgaaaata tagaagcgat actccgccta cggagaaaaa tacaagcttt taagagagaa
    10021 gtgggagata ccttgtttat tagtcctcgc tatcctaatg gagctacatg gagagaggaa
    10081 gccctaaaag aattgccaga ctattttaat actatttttt tagaaaactt tggccatgag
    10141 ctttatactc aagcacctaa agaaatcgct agtctaatga atgagtggct cgcttatttt
    10201 ctatgagcta cttgtattgc tggaaatggt ataagatgaa aatctacaag tcactaattt
    10261 tcatataaca aaaaaacgaa caggctcttt ttctgttatt cagaagagaa cttgttcgtt
    10321 tttatcttga ttttcttaaa aagctctata tacataggga ttttctggtt tatcgacttt
    10381 ggtaaagctg tcgatttcca aggttggaag gttttgtttg agttctttat ggtagtgatt
    10441 gaccagtttt cctttggctg taatccaggt gttgttttca tactgccggg tattgccctt
    10501 ggtcagcaat ccatagacac cagaatctgc gatacagtgg ataatgccga atcggaacag
    10561 aaattgacta ttggcatgac tggggtcgtt atagacaaag cctgtaaact ggattgtctt
    10621 gccctcaaat tcatctggat agtcgtagat agcctccatg acttccatat agttttcatt
    10681 agtgatctga atactatctt gggataagta tttatccgcc gccgttcgca tttccttttc
    10741 ataggctgat tttgaaaaat aagaactagt atctggtttc aaatattggc ttgtcgtccc
    10801 ttcacttgtc tgaatagcta gatccgttcc ttccgatagg gggaaatgat aacctttagc
    10861 agaaacggtc tgagaatcca agctaacagt tgggaaagtt aagccgatga caagtggaat
    10921 agccagaaga gaaatactcg tcatcttggc caatcggctg ttcagatgac tgtgggtttt
    10981 gacttgcttc atccagatat acaattgaac aattgccaag ataaaggaaa gcaccatgga
    11041 gatataggcc agataggaat agtgcatgtt gatgtactgg tttagtttgc ccgacagatg
    11101 gaggtaaata gtcagttcaa aatagccagc taaaactaaa aatcgaatca taggatgact
    11161 ccaatcaaga gagaataggc taaaacgacc agagtcacaa tcgtaatgaa gtgactaata
    11221 aatcgtgctt tcaagtaatt tttcatcatg agaatatttt tgatatccag cattgggcca
    11281 atgacgagaa aggccagaac tggtgccaaa ccgaaactcg agagaagaga agcacctata
    11341 aaggcatccg cctcactaca gagcgaaaga agaaaggcca aaatcatcaa gagcaggatg
    11401 gcaaaaagag gagtcgcact gatagaggtc agaatccgag tcggaacgta gacctgtatt
    11461 atagaagcaa agaggcagcc aaataccaaa taacgccccg tatcaaaaaa ttcatcaatg
    11521 gcctgcacaa agacttgaaa aacttttttt gcagaactca agtaagaaaa atcatgctca
    11581 tgacaagcca gacgattttc tttctgaatc ggttcttgcc agaaaaatcc tagaaaaatt
    11641 cctagtatta cagccacaag aatggaaccc agagctcgta atagggcgac atggaaggag
    11701 ttgccaaagg cagaataggt cgcaaaaaga acaatgggat tgataacagg tgctgtcaca
    11761 agaaaaggaa cggctgtgta actgggaacc tttttttcca gaaaacgatt gatgatgggg
    11821 acgattccac attcacaaga agggaaaagc ataccgacaa aggtcccaaa aaagattctc
    11881 ccccaacgat ttcgagggag aaaatgataa accttgtcag gtgtgatata aacttcaatc
    11941 agccctgaga caatgcttcc tattagaacg aagggaaggg cttcaatgat aatggagaga
    12001 aaaatggctc cagtttgaag tacactagat gggagttgtt gaaaagcagt catctagttt
    12061 ttcttttctg ctttggcttt tttctctttg tcatcaggga aagtaacttg tttcaaatca
    12121 gggagtttag caaactcttc aaacatcttg tccaagtcgt ctcgttttgt aaattttaca
    12181 gccataggtg tacctcgatt ctaaagtcta cctctattat actattattt tgcggaaaag
    12241 ggagtttttt aatttgtttt cgatagttga tacacttcga aaatctcttc aaaccacgtc
    12301 agcttcgcct taccgtatat atgtgactta tccacaacct caaaacagta ttttgagcag
    12361 cctgcggcta gcttcctagt ttgctttttg attttcattg agtatgaaaa ggattggaga
    12421 aagccttcca gcttgtggta taatagattt atggataaaa aatatgaaaa aatctctcag
    12481 gatttgggag tgatgttaaa gcaaattgat accgttctaa gtttgacagc tgaaggggcg
    12541 actattccct ttatcgcgcg ttatcgcaag gacatgactg gtagtctgga tgaggtggcg
    12601 attaaggcta ttattgattt ggataaaagt ctgacaaatc tcaatgaccg taaggaagct
    12661 gtcttagcta agattcaaga acaaggtaag ttgaccaagg aattggaaga agctatctta
    12721 gttgccgaaa aattagcaga cgttgaagaa ctctatcttc cttataagga aaagcgtcgt
    12781 accaaggcaa ccattgcccg tgaagctgga ctctttcctc ttgctcgttt gattttgcag
    12841 aatatagttg acttagagaa agaagctgaa aagttcgtct gtgaaggatt tgcgactggc
    12901 aaggaagcct tgaccggtgc agttgatatt ttggtcgaag ccttatcgga agatgtgacc
    12961 ttgcgttcta tgacttatca ggaagtgctg agacactcta aacttacttc tcaagccaag
    13021 gatgaaagtc ttgatgaaaa gcaggttttt cagatttatt atgatttttc agagacagtt
    13081 ggaactatgc aaggctatcg taccttggct ctcaatcgtg gggagaaact tggtgtcttg
    13141 aagatcggtt ttgaacatgc gacggaccgt attcttgcct tctttgctac tcgtttcaag
    13201 gtgaaaaatg cttatattga tgaagttgtt cagcaatccg ttaagaaaaa ggtcttgcct
    13261 gctattgagc gtcgtattcg gacagaatta actgagaaag ctgaagaggg agctatccaa
    13321 cttttttctg acaatctgcg caatctcctc ttggttgctc cattgaaagg gcgcgtggtt
    13381 cttgggtttg acccagcctt tcgtacaggt gccaagctag ctgtcgtgga tgcaacagga
    13441 aaaatgctga caactcaggt catctatcct gttaaaccag catcagctcg tcaaatcgaa
    13501 gaagccaaga aagatttagc agatttaatt ggtcaatacg gtgtagagat tattgccatt
    13561 ggaaatggaa cggccagtcg tgaaagtgaa gcttttgtag cggaagttct gaaagatttc
    13621 cctgaagtca gctatgttat cgttaatgaa agtggtgctt ctgtctattc tgccagcgaa
    13681 cttgctcgtc aggagtttcc agacttgacc gttgaaaaac gctctgccat ttctatcgcc
    13741 cgtcgtttgc aagatcctct tgcggaattg gtcaaaatcg atcctaagtc aattggtgtc
    13801 ggtcaatacc aacacgatgt cagtcagaag aaactatctg agagtctgga ctttgttgtc
    13861 gatacagtgg ttaaccaagt tggtgtcaat gtcaatacag ctagcccagc tcttctttca
    13921 cacgtagctg gactcaataa aaccatttct gaaaatatcg tcaaataccg tgaggaagag
    13981 ggaaaaatca cttcacgctc ccaaatcaag aaagttcctc gtttgggggc caaggctttt
    14041 gaacaggctg ctggtttcct ccgtatccct gaaagtagca atatccttga taatacagga
    14101 gttcacccag aaaattacgc tgccgttaag gaactcttca aatgcttgga cattaaggat
    14161 ctgaatgaag aggcccaaag taaactcaag tcgctttcag tcaaggaaat ggcgcaagag
    14221 ttagaccttg gtccagaaac tcttaaagat atcattgcag atcttctcaa accaggtcga
    14281 gatttccgtg attcctttga tgctccagtt ctccgtcaag atgtcctaga tatcaaggac
    14341 ttagtggttg gacaaaagct agaaggagtg gtgcgtaatg ttgttgattt cggtgctttt
    14401 gttgatatcg gaattcatga ggacggtctc atccatattt cccatatgag tcgcaagttt
    14461 atcaaacacc ctagtcaagt ggtggcagtt ggagatttgg tgagcgtttg ggttaagaaa
    14521 attgatactg aacgtgaaaa agttaatctg tctctcctag ctccaaatga aactgactga
    14581 ttacgtcaag caggtttcac tagaagactt cggcagacct tttatccatc atgtccagtg
    14641 gaataggcgt ctacgttcga caggtgggcg atttttcccc aaagatgggc atttggattt
    14701 taatcccaag gtttatcagg aactggggtt ggacgttttt aggaaaattg tccgacatga
    14761 actctgtcat tatcacctct attttcaagg gaaaggctat caacacaagg atcgggattt
    14821 taaggaactg ttgaaagcag tggatggatt acggtttgta ccatccttgc ccaatagtaa
    14881 ctccaagcca atcaagctct atcgttgcca atcctgccag caaacttatc agcgtaagcg
    14941 taggattgat acccaacgct atcgctgtgg actttgtcga ggaaagttgc tattagtaaa
    15001 tcagcctgag gactgatgaa agccgagcct atccgtgata tactagtcta acctagcaga
    15061 aagaggaaat atcatgaaca gtaagtttta taaaatgaga cgaaatcgca tgatttcagg
    15121 agttttagca ggtctgtcag acaagtggaa ctttgatgtt acccttgtac gttttctgtt
    15181 tgccattttt acagtcgcaa actttggact tggggtgatt atctatatca tcctagcttc
    15241 tatcatgcca accaaggaag aaatcgaagc agaaatgtac ggaacaggcc cacgtaaacg
    15301 caaagaagct caagccattg acgataatga aggctggttt tggtgaggtt ttacaaaaga
    15361 tttggaatac gcaaaaagct ttaaatcaat agtctaaact gcttgattta aagctttttt
    15421 acttttatac tcaataaaaa tcaaagtgca aactaggaag ccagccgcag gctgtaattt
    15481 agtcggcaat gtgaagttga tatagtttgc actttgattt ttgaatagta ttaataatat
    15541 ttcgccagct tcatccacaa actatagtgg attggaacta gaataggaca cctatacttc
    15601 taaaaaattg ttagaaatcg atttgactgt cctgatcgat ttgtcctgtt cttatttcat
    15661 tttattataa aagcagtaat ttaaacgcag ttttttaatc tatttttgct gttgagacaa
    15721 tacatttttg gaaaaatggt ggatgctgat aacaactgat aaccagcaaa taacataagc
    15781 agtgccggta aattctgtac tgataaagtg tgtgtgttca actaagagct gaccgatgaa
    15841 tggagagagc agatagagaa gtccgatgag tatatgttct ttgtgtttca ttaaagcgca
    15901 ccttctttcc ttataggttg aacgacttgc aagtgttaaa ttgaatggta tgttatctag
    15961 gtaagcttac taaaatgtta gttcccgctt cctccttttc aaagtaagcc ttttcacact
    16021 tatattttac aactttaaaa ataggaaatc aaatcatttt ctaagtaatt ttgcttatat
    16081 ttcacccaat cttacaaaaa tgtaagatta aagtctcttt tgtaaggtta ggttatggca
    16141 agcggtcttt ttttgatgta aactagactc ataaagaaca aaggagtaac atcatgaaac
    16201 aaatcttaca taagaaaact agaaaaccaa gtcacaaaga aattgagcgc gttcagctgg
    16261 gatgcactat gatgcaagct acatttcatt tgatgggata ttaagaaagg agattctcat
    16321 gacactttta gatgtaaaac acgttcaaaa aatttataaa acacgttttc agggcaacca
    16381 agtagaagcc ctcaaggata ttcactttac cgtagaaaag ggtgactacg ttgccatcat
    16441 gggtgagtct ggttctggta aatcaactct tctcaatatt ctagctatgt tggataaacc
    16501 aactcgtggg caggtttact tgaatggaac tgacaccgca actattaaaa attcacaggc
    16561 ttctagtttc cggcgtgaaa agctaggatt tgtcttccaa gactttaact tgctagatac
    16621 tctgtctgtt aaggacaata tcttgcttcc gcttgtcttg tcaagaagac ctataacgga
    16681 gatgatgaag aaattggtgg tgacagctga gaatctgggt attaaccaat tgcaagagaa
    16741 gtacccttac gagatttctg gtggccagaa acagcgtgta gcagtagccc gcgccatcat
    16801 cacagaacct gaaattctcc ttgcggacga gccaacagga gcccttgatt ccaagtcatc
    16861 tgcaacctta cttgatgtct ttaatgaaat caatgagcgt gggcaaacca tcctcatggt
    16921 aacccactca acagcagctg ctagcagggc caagcgtgtt ctctttatca aagacggcat
    16981 tctttacaac caaatctacc gtggagagaa gacagagcgt cagttgttcc aagaaatctc
    17041 tgataccttg actgtcatgg caagcgaggt gaattagtat gtttcgatta accaataagt
    17101 tagcggtatc gaacttgatt aaaaaccgca aactctacta tccctttgca ctggctgttc
    17161 tcttggcagt caccatcacc tatctctttt actccctaac cttcaatccc aagattgcgg
    17221 aaatccgtgg aggaaccacc attcaagcaa cacttggatt tggtatgttt gtcgttaccc
    17281 ttgcgtcagc cattatcgtc ctctatgcca atagttttgt catgaaaaac cgttccaagg
    17341 aactgggtat atatggcatg ttaggcttgg agaagcgcca tctaatcagt atgaccttta
    17401 aggagttagt gctatttggg attctaactg ttggagcagg aatcggtatt ggagccttgt
    17461 ttgacaagtt gattttcgct ttcctactca aactgatgaa attgaaggtg gaactggtcg
    17521 ctaccttcca gatgaaagtt gtcattacag tacttcttgt cttcggtttg attttcctag
    17581 gcctcatgtt cctgaatgcc cttcgaatcg cccgtatgaa tgccctccag ctctcacgtg
    17641 agaaagctag cggagagaaa aaaggtcgct tccttcctct ccaaactatt cttggttcca
    17701 taagtttagg gattggatat tatcttgccc ttacggtaaa agatcctctt acagccttaa
    17761 caaccttctt catagctgtt ttactggtta tctttgggac ttatcttttg ttcaatgcag
    17821 ggattaccgt tttccttcaa atcttaaaga aaaataagaa atactattac caacctaata
    17881 atctcatatc tgtttctaac ttgattttcc gtatgaagaa aaatgcagtt ggactagcaa
    17941 ctatcgctat tttgtcaaca atggttttgg taaccatgtc agcagcgaca agcattttca
    18001 attccgcaga atcctttaaa aaagttctaa atcctcatga ttttggggtt tcagggcaaa
    18061 atgttgaaaa agaagatttg gacaaactct tgagccagtt tgcaagtgac aaaggttata
    18121 agattaaaga gaaagaagtg cttcgttaca gtaactttgg tattgcaaat caagaaggaa
    18181 ccaagttaac tatttttgaa aaaggacaaa accgtgtcca accaaaaaca gttttcatgg
    18241 tatttgacca aaaagattat gaaaatatga ctggtcaaaa actgtctcta tcaggaaatg
    18301 aggtcggtct ctttgccaaa aatgacggac tgaaaggaca gaaagctcta actctaaatg
    18361 atcatcaatt ttctgtcaaa gaagaattta ataaagattt cattgtcaac catgttccaa
    18421 ataagtttaa tatcttgact actgattaca attaccttgt tgttcctgat ttacaagcct
    18481 ttttggatca attcccagat tcggctatct ataatcagtt ttacggtggt atgaatgtag
    18541 atgccagcga agaagaacaa ctcaaggtcg ctgaggagta tgaaaactac ctcaatcaat
    18601 ttaatgctca attagacaca gaaggtagct atgtttatgg tagcaatcta gcagatgcta
    18661 gttctcagat gagtgccctc tttggtggtg tcttctttat cggtattttc ctatccatta
    18721 tctttatggt cggaactgtt ctggtcatct actacaaaca aatttctgaa ggctacgaag
    18781 accgtgaacg ctttattatc ttgcagaaag tcggtttgga ccaaaagcaa atcaagcaaa
    18841 ccatcaacaa acaggtttta actgttttct tccttccttt gctctttgcc ttcatacatc
    18901 tcgcctttgc ctaccatatg cttagcctga ttttaaaagt gattggtgta ctggatacga
    18961 ctatgatgtt gattgtgacc ttgtctatct gcgctatctt cctcatcgcc tatgtgctga
    19021 tttttatgat tacttcaaga agttatcgca agattgtgca aatgtaaaaa agatacctcg
    19081 acttcaaaat cgaggtattt cttgtattct aaatgctgaa aagttgttcg agcaggaagg
    19141 taactcccct ggtcaagaga ccaatagcaa ggttccgaat catagctgtt ctagtcggat
    19201 cctttccaag tctggcacta gtgtaaccag tgagaagaag ggccacaccg acaataagga
    19261 cagtagcagg gatgcgatat tcacttggga atatggtcac tgacagcatt ggaggcaaac
    19321 ttctaaggaa aaaggcaacg aagctagaaa tggcagcgtg ccaaggattg gtaaattctt
    19381 catactcaat cccatatttt tcctctacca gagccttgag tggattttta agaaagatct
    19441 tattagccaa gagttgggca gaagttttgc attctccatt ttggatataa gcagcataga
    19501 gggatttttt ggctagttcc ctatcttggt ctagcaagag tttttctcgc aaaacggcag
    19561 cttcctcggt atcttttgga gttgaaacgg atacatattc tctaccagcc attgaaaagg
    19621 caccagctaa gatagccgca aaacctgata aaaagataat ccagatattg gtcgtggtac
    19681 tggcaactcc gataaccaca ccagcaatgg aaataattcc attgttagca tcaagaacac
    19741 ccgcacgcag gatatttaaa cgacctgcaa aatttgaatc aatttcgtga tttgtttctg
    19801 acgctaaatt tcaagttcaa gttagccatc aagaagtctt ctctgggtga cttgtagttc
    19861 aagcattttt taggatagtt gttaatccac ttttcgatga atgcgacttc tttgggagtc
    19921 attttcttgg ttcccttagg taaccatcta tgaatgagcc tgttgtgatt ctcattagtt
    19981 cccctttccc aagaggcata ggggtgcgca taatagatgt gctcctcaga aaatacatca
    20041 aacaagcgat tgaattccgt tccattatct gccgtgatgg aaagaatctt gtgttgtttt
    20101 aagatgagtt ttagagcctg attgaccccc tcagcacttt tatttggaat caatcggatg
    20161 atctgatgtc tactctttcg atccgtcaag acaagcaagc agtagttttt cgctctcgta
    20221 agtagaaccg tatcaatctc ataatgccca ttctccaagc gaagattgat agcttcaggc
    20281 cgctgttcga tggattgacc agcaggttta aagttggtgc tagcctgttt cttaagcgct
    20341 tttccttttc tagggtaaag cagatcctgc ttgcttaacc ccaattttcc acgatgaatc
    20401 caatagtaaa tggttgaaat tcccacgtta acccctttag caataaccat catttcaggc
    20461 gaaaattttt ggttatgata gtggagaatc ttttccttta gttccttggt caagcttgat
    20521 ttcttgaccg agcgcttgcg attgttttca taagactgtt gagcatagtc ggcagaataa
    20581 acctctttga agcgcccttt tccaagacat tgtcggactg tcccacgctt gatttcagtg
    20641 tggatagttt gaggagcttt tccaagtaga gaggcaattt ctctatttga tttcccttct
    20701 tttttccatc tttcgattaa gcgacggcta tcgattgtca aatgtttggc ttttgtagta
    20761 taattgtctt gcatctctgt gcctttcttg tgtttgtggt tgaacaacaa gtataacaca
    20821 gaggtgtttt cttatgccta caagagctat cagctagttg aaccatctaa tttttaggag
    20881 ggctgggtgg ttaacttcat tatagaactt tcatttacga acatatagta aaatgaaaca
    20941 agaacagaac aaatcgatca ggacagtaaa atctatttct aacaatgttt tagaagcaga
    21001 ggtgtactat tctagtttca atctattata tttttgtttt ttatcaaaaa atactttaca
    21061 agttcttaaa aacatgatat agtaataaag cttagaaaat gagatgatgt tttctagcaa
    21121 atataaaccc gagtaaaaaa tgcctacgga caggcagggt tgaatgccga agcgtggttg
    21181 aaaagccaca ttattgatag ggttaaaagc ctacttttat aagttgatgt taggacactt
    21241 gtcctaattc ataaattttt agtgtggtga aagcacacgt catcttgtga aacgatcaat
    21301 aaagtacgta atatttgcta ctagagagtt aggaaacatc gggaacagac atactcaaca
    21361 gaaaccaaaa taaacacgtc agaagattgc agagcaggtg aaaacctgct cttttttcat
    21421 gagtcaacct ttagttcctt agttttcata aggtcctaaa aatattgaaa ggagtatgtt
    21481 ttgaaagagt tagatcaaaa ccaagcccca atttatgagg ccttggtgaa gttacgcaag
    21541 aaaaggattg ttccctttga tgttccaggt cacaagcgtg gacggggaaa tccagaactt
    21601 gtcgaactct taggagaaaa atgtgtaggc attgatgtca attcgatgaa acccttggat
    21661 aatttaggcc atcctatttc gattattcgt gatgcagagg agctggctgc agatgctttt
    21721 ggagctagcc atgcctttct aatgattggt ggaacaactt catcggtgca gactatgatt
    21781 ctggcaacct gcaaggcagg agataagatt attctgccac gaaatgtcca taaatctgct
    21841 atcaatgcgt tggttctatg tggtgccatt cccatctata tcgagatgag tgtagatcct
    21901 aagattggta tcgctttagg tcttgaaaat gaccgagtag cacaggccat aaaggaccat
    21961 ccagatgcta aggctatcct aatcaacaat cctacttact acggcatctg ttcagaccta
    22021 aaggggttga cagaaatggc tcatgaagct ggcatgatgg ttttagtaga tgaagcccat
    22081 ggagcgcatt tgcatttcac tggtaaactt ccaatttctg ctatggatgc aggagctgat
    22141 atggcagcag tttccatgca taagtctggt gggagtttga cacaaagttc gcttctttta
    22201 atcggggagc agatgaatcc cgagtacgtt cgtcagatta taaacctgac ccagtctaca
    22261 tctgcctctt acttgttgat ggctagtttg gatatttcac gtcgcaactt ggcccttcgt
    22321 ggtaaagagt cgtttgagaa agtcattgag ctatctgagt atgcccgccg tgaaatcaat
    22381 gctatcggtg gctactatgc ctactcaaaa gaattaatag acggtgtttc ggtttgcgat
    22441 tttgacgtaa ctaagctgtc agtttacact cagggtattg gcttaacagg tatcgaggtt
    22501 tatgacctct tgcgagacga atacgacatt cagatcgagt ttggtgatat cggcaatatc
    22561 ttggcctata tttctatcgg cgaccgcatc caagacatcg agcgcttggt tggtgctctg
    22621 gctgatatta agagactcta ttcaagagat ggaaaagatt tgatagcagg agaatatatt
    22681 cagcccgagt tagtgctgtc tccgcaagaa gccttctatt cagcaagaaa aagtttaact
    22741 ttggatgatt ctgttggaca ggtctgtgga gaatttgtca tgtgctatcc tccagggatt
    22801 cctatcttgg ctcctggtga acgcattaca cgagaaattg tcgactatat ccaattcgcc
    22861 aaggaacgtg gttgctccct ccaagggacg gaagatccag aggtcaatca tatcaacgtt
    22921 attaagagaa agacaaacta taagaaaagt caatagtttt atctaaacta tttcttattt
    22981 caatttgatg atttggcgat gattttagag cacggcaaaa agcccttgaa ttagaagcgg
    23041 tcaatcgctt aatttctatc agcttatcaa atcctgcctc aatccttttc tgaggattag
    23101 ggtagcgtgt caagagttgg taggtatatt ctgaatgctt tccaacgatt ttatccaact
    23161 caggaaagat gatatcaaga caacgagtgt attgtacttt ccaatcagac tgttttttct
    23221 tgagacgatg aatatgtcta gtcagtattt ttagttctac ttgccgatta tcgtgttgaa
    23281 attgttcacg attggggtca gaaagaagtt taagagcgat gccatgagcg tctttcttat
    23341 tcgttttagt cttgcgaagt gataatgatt tggcaaattc cttgatgagc aaaggagtgt
    23401 aggtgtaaac tttatatcct tgttcatgca ggaagttcag tagattaaag gcataatgtc
    23461 cagtatcttc aagagcgatg agacagtctt ggttgagctg tcgaaaagac agatctaaga
    23521 gttcaaaacc agctttatta tttgaaaaag tgagtggttt aagaacagtt ttcctcgaac
    23581 attcaaggct gtaacatcgt gtttattttt agcgacatca atacctacat aaagcatggg
    23641 agtacctcca gatatagtat ttcaagtcta cttggttatc cacgaacttt ttgccttgtt
    23701 accttagacg agataaaacg tctatgcgtt atcaaactca ttaccaattg aaacaaaaag
    23761 ctgtggttag agcctttcgg aaatcgtcaa gcgattggag gaaatgaact aatccacagt
    23821 gacttattcc aagtatacca cttgggcttt ggcagtagct aactgcgcta aatataatat
    23881 aaggagaaat agatggattt atggttttct gaagttcata ctccagatgt caaattgtct
    23941 ctgagaacag ccaagcaact ttacgctgga aaaagtgaat ggcaggatat cgaagtcttg
    24001 gatacgccag cttttgggaa aatactgatt ttaaatggcc atgtcttgtt ctcagatgcg
    24061 gatgatttcg tctacaatga aatgaccgtc cacgttccca tggctgtcca cccaaatcca
    24121 aagaaagtat tggttattgg gggtggtgac ggcggtgttg cccaagtatt aacactctat
    24181 cctgaactgg aacaaatcga tatcgtggaa ccggatgaga tgttggtcga ggtctgtcgt
    24241 gagtatttcc cagactttgc tgcagggcta gatgatcctc gtgttaccat ttactaccaa
    24301 aatgggctac gctttttgcg aaactgcgaa gatgattacg atattatcat caacgatgcg
    24361 acagatccat ttggccatac ggaaggactc tttaccaagg aattctacgg caatagttat
    24421 cgagctctga aggaagacgg catcatgatt taccagcatg ggagtccctt ctttgacgag
    24481 gatgagtcgg cctgccgaag catgcaccgc aaggtcaatc aagcctttcc aatcagtcgg
    24541 gtttatcagg cccatattcc aactagccca gctggctatt ggttgtttgg atttgcatcg
    24601 aaaaaatacc accctgtcaa agattttgac aaggaaggtt ggaaaaaacg ccagcttttc
    24661 acagaatact acactgcaaa cttacacgtg ggatccttta tgttgcccaa gtatgttgag
    24721 gacattttag aagaagagga aggaaaaaaa tgagtcgttt actagttatt ggttgtgggg
    24781 gcgttgccca agttgctatt tcaaagattt gtcaagatag cgaaacattt acagagatta
    24841 tgattgctag ccgtaccaag tcaaaatgcg atgacttgaa agcgaagcta gaaggcaaaa
    24901 caagtactaa aattgaaact gcagcacttg atgctgacaa ggttgaagaa gtgattgccc
    24961 tgattgaaag ctacaaacca gaagctgttt tgaatgtagc tctgccttat caagatttaa
    25021 ccattatgga tgcttgtttg gcaacaggtg ttcactatat cgatacagcc aactacgaag
    25081 cagaagacac agaagaccct gagtggcgtg ctatctacga aaaacgttgt aaggaacttg
    25141 gttttacagc ctactttgac tactcatggc agtgggctta tcaagagaaa ttcaaagaag
    25201 caggcttgac tgctcttctt ggttctggtt ttgacccagg tgtaactagt gtcttttcag
    25261 cttatgccct caaacactat tttgatgaaa tccattatat cgacatttta gactgtaatg
    25321 gcggtgacca cggttatcca tttgcaacca actttaatcc agaaattaat ctccgtgagg
    25381 tttctgcgcc aggttcttac tgggaagatg ggaaatgggt cgaagtcgaa gctatgtcta
    25441 tcaagcgtga gtatgatttc cctcaagttg gacaaaaaga tatgtatctc cttcaccatg
    25501 aagaaatcga atcattggcc aagaacattc caggtgtcaa acgcattcgt ttctttatga
    25561 cttttggtca atcttacttg acgcacatga aatgtcttga aaatgttgga ctccttcgta
    25621 cggataccat taactttaac ggccaagaaa ttgttccaat tcaatttttg aaagccttgc
    25681 ttccagatcc tgctagcctt ggcccacgta ctgtaggtaa aaccaatatt ggatgtatct
    25741 ttacaggtgt caaagatggc gttgaaaaga ctatctacat ctacaatgtt tgcgaccatc
    25801 aagagtgcta tgcagaagtc gggtcacaag caatttcata cacgacagga gttccagcca
    25861 tgattgggac aaaattagtc atgaacggaa cttggaaaca agctggagtg tataaccttg
    25921 aggagttaga tccagatcca ttcatggaag ctttgaatga gtatggtttg ccatgggttg
    25981 tggttgaaaa tccacaaatg gtggactaat gaagttagaa caagtaccaa caccagccta
    26041 tgttattgac ttggccaagt tagaagctaa ttgccgcatt ctacaatatg tacaagaaga
    26101 ggccggttgc aaggtcttgc ttgcccagaa ggcatattcc ctctacaaaa cttatccctt
    26161 gattagccag tatctatcag gtacgacagc tagtggactc tatgaggcca aattggcaag
    26221 ggaagaattt cctggtgaag tccatgtatt tgcgcctgct ttcaaggatg cagacttgga
    26281 ggaattgctt gggataacag accatatcgt ctttaactca gagagacagt tgcgtaagca
    26341 tggggctcgt tgtcgagagg ctggtgtcag tgttggtttg cgcctcaacc ctcagtgttc
    26401 aactcaagga gatcacgcgc tctatgaccc ttgtgcacca ggttctcgct ttggagttac
    26461 tatagacaag attccgagtg atttgctaga tttggttgac ggacttcatt ttcataccct
    26521 ttgcgagcag ggagcagatg atttacaaac aactttgaaa gcagtagaag aacaatttgg
    26581 tccctactta catgaggtaa aatggctcaa tatgggtggt ggtcatcata ttacaagaga
    26641 aggttacgat gtggatttgc tgatttcaga aatcaagcgt atccgaaaaa cttacaatct
    26701 tgaaatctat atcgagcctg gtgaagccat tgcgcttaat gcgggttatt tagcaactga
    26761 ggtattagat attgtagaaa acggtatgga aatcttggtt ttagacgcct ctgcgacctg
    26821 ccatatgcct gatgtacttg agatgcccta tcgtccacct ttgagaaatg gctttgaggc
    26881 acaggaaaaa gcccatacct acagactttc ttctaatacc tgtctgactg gcgatgtgat
    26941 tggtgattat agttttgaaa atccagtcca aatcggagac agactttatt ttcaagacat
    27001 ggccatttat tcttttgtca aaaataatac ctttaatggt attggattgc caagtctcta
    27061 tctcatggac gaacagggag actgtagctt actcaaagct tttggctatc aagactttaa
    27121 agggagatta tcatgatgga cagtccaaaa aaattaggct atcacatgcc agcagagtac
    27181 gaaccccatc atggtaccct catgatatgg ccgactcgac caggatcatg gccttttcaa
    27241 ggaaaggctg ctaaaagagc atttactcag atcatcgaga ccatagcaga aggggaaaga
    27301 gtctatcttt tggtggagca ggcctatcta tctgaagccc aatcctatct tggagacaag
    27361 gttgtttatt tagacattcc caccaatgat gcctgggcgc gtgatactgg cccaaccatt
    27421 ctcgtcaatg ataaaggtaa gaaattagcc gtggattggg ccttcaatgc ttggggaggc
    27481 acctatgatg gtctttatca agattatgaa gaggatgacc aagtagccag tcgttttgct
    27541 gaggctttgg aaaggcctgt ctatgatgct aaaccttttg tactggaagg aggcgcaatc
    27601 catagcgatg gtcaaggaac tattctcgta actgaaagtt gcttgcttag tcctggtcgc
    27661 aatcctaact tgactaaaga ggagattgaa aacacattat tagaaagtct tggtgctgaa
    27721 aaagttattt ggcttcctta tggtatttat caggatgaaa ccaatgaaca cgtcgataat
    27781 gttgctgcct ttgttggtcc tgctgagctt gttttggctt ggacagatga cgaaaatgat
    27841 ccccagtatg ccatgtcaaa agcagatctc gaactcttag aacaggaaac agatgcaaaa
    27901 ggttgtcact tcaccattca taaattgcct atccctgtag ttcgacaagt tgtgacagaa
    27961 gaagatttgc caggctacat ctatgaagaa ggagaagaag agcgatacgc aggtgaacga
    28021 ctagcagctt cctacgtaaa cttttatatc gccaacaagg ctgtcttggt tccacagttt
    28081 gaggatgtaa acgaccaagt ggccatagat atcctcagca agtgtttccc agaccgtaaa
    28141 gttgtcggaa taccagccag agatattctc ttaggtggtg gtaatatcca ctgtatcacc
    28201 caacaaattc cagaatagga gaaaaagatg agaaatgtaa gagttgcaac cattcagatg
    28261 caatgcgcta aggatgtggc aacaaatatc caaaccgcag agcgtttagt acgtcaggct
    28321 gctgagcaag gagcccaaat tattctcttg cccgagttgt ttgaacatcc ctatttctgt
    28381 caggaacgtc agtatgacta ctaccagtat gcccaatctg tagcggaaaa tactgccatt
    28441 cagcatttta aggtgattgc taaggaacta caagttgttt taccaatcag tttctatgaa
    28501 aaagatggta atgtcttgta taactctatt gccgtcattg atgcagatgg ggaagtgctg
    28561 ggcgtttatc gaaagaccca cataccagat gaccattatt atcaagaaaa attctatttc
    28621 acgcctggta acactggttt caaggtctgg aatactcgct atgctaagat tggtatcggt
    28681 atctgttggg atcaatggtt ccctgaaaca gcgcgctgtc ttgcattgaa tggtgctgaa
    28741 ttgctctttt atcctacagc tatcggttca gagccaattt tggatacaga tagttgtggt
    28801 cactggcaac gtactatgca agggcacgca gcagcgaata ttgttccagt catcgcagcc
    28861 aatcgttatg gtttagagga ggttactcct agtgaggaaa atggcggaca gagttccagt
    28921 cttgacttct acggttcctc ctttatgacg gatgaaacag gagctattct agaacgagct
    28981 gaaagacaag aagaagctgt tctgttagct acttatgacc tagacaaggg agcaagtgaa
    29041 cgcctaaact ggggcttgtt tcgagataga agaccagaaa tgtatagaca aattacagat
    29101 tagtgtggga gaaatgagag attcattctg ctagactaac ttcttattag caactataag
    29161 atactatggc atctagtaaa tcgattttta tgattcgcta ttcttgtcta ttgattagtc
    29221 cgtattttaa aatattagca aaaaagcaaa tagcagtaac ttctgtctat ttgcttttct
    29281 tttttataga atatatttct caatagcacg cgcaacgccg tcttcttcgt tgcttgaggt
    29341 aacggcatcc gcaagagatt tgacataatc gctggcattt cccattgcaa tcccaagccc
    29401 tgcaaactgg agcatttcga tatcgttatt agcatcgccc atggccataa tctctgagga
    29461 atcaatcttc aaaatctcag ctagtcgtga aagagcagta gcctttgtcg ttccaagtgg
    29521 cattgcttca taaatgacag gctgcgaacg aactccactg aatcgttggc aaagctcttc
    29581 agcaaaacgc tgctcaaaat cgtctgtttg ttcttttgtt cctaaaaaca taccttggaa
    29641 catccggaac tttccactag tcgcttcctc aagagaaatt tcagtcaggt ctgaaaatac
    29701 tagtttagca tcattttcaa taacttgatt gggcttgcca ccgagaacaa aataatgtga
    29761 ctcgtcaaaa agtgtcaact gaacatcact cttttcagca aggtcataga ggtattcgat
    29821 gtcagctgga ctcagttctt tccagtcaac tagaccccaa tcactggttt ggtgagttga
    29881 acaaccgttg ttaacaataa catattcgtt ctggaggtca agccccagtt ttttgtagta
    29941 ggggaggaca ccgaaaaggg ggcgacccgt acagagaacc agtttgacac ctttttcaat
    30001 ggctttgtga atagcagtaa tgtgagcttg tgggatttcc ttggcttcat tgaggagggt
    30061 tccatccata tccaaggcta gtagtttaat cataggtctt ccttctttat cttttggtag
    30121 tattatagca tattttggag aagaaattga tagaaagctt gagactaatt gattttatag
    30181 tttaagatgt tttgatgaca attcatgatt tgaagaggat atttggcaaa gatatgctat
    30241 actatgtttg tcaatgttgc aactagacaa attaaaaaac caacttaata taatagtttt
    30301 tttgtaagta ggtatgagta tcagattact caactaatct gaagaataat ggaggaaata
    30361 tatcatgatt ttaatgacaa aaaatataaa tctaacaaat gaagaattag agctgataca
    30421 aggtggagca gattcatatg gtaaaaatcc taatggtagg tacgattggg aaatagaacc
    30481 agtattaact ctgccggttc atggattttg tcccagaggc acctatgatt taggatatat
    30541 tggaggaggc aatcatcttt gcaaaggaag tgctgcgaga ttttaagtaa aatttattag
    30601 taatatgaag aaacaagtgg agaaagcaga gaatttaata tgaaaaaacg ggctattcaa
    30661 attttactag cattgtcctt aattttttac aaatcaactt ggttttggag agttttcaat
    30721 cacctcgcaa agccctatct accagcaagt cgtgaatttt ttcagattct gcttttgatg
    30781 gagagcggag ttcttttctt agcggtcatc tatctactgg tttttgcagg aaagaaaatt
    30841 tttcatttca agtggcagct gaggtacttc atctaccttt tactgggcta catcatttca
    30901 tatatgtctg acttcctctt ttcgtatttc atatccctgt cttcaaatca gatttctttg
    30961 aatgaaacgg tagaaatgat ggggagacag gagttccctt atttcttgct catcgtttgc
    31021 ttcatcgccc ctattgctga ggaattgatt tatcgaggtg tgcttatgac aacctttttc
    31081 aaaaactcac cttggtacgg agatgttttg ctttctgcta ttattttcgg ttatattcat
    31141 atcaattttg ctttaactcc tcttgctttt ttcatttatg ctagtggagg tcttatttta
    31201 gctctattgt atcgcatgac taaaaatctc tactatccaa tactagttca tattctcatt
    31261 aatatcactg ccttctggga tgtgtggttg ctcctatttt caggaagtta gcttactaaa
    31321 ataatgtcgg aactttccgg cattttcttt tttcacaaat agtcaacggt tttcttttcg
    31381 atattgtagt ggtgtgtatc cagttatttt tttgaattga ttttgaaaat aaggttggct
    31441 tgagaaaggc agatagtgaa gatagttaag aagaagagga tgttcttttt tcctttttgg
    31501 aaaacttcta aaatatggta taatgaaaag ataaagaagt taggggtaga agatgaacat
    31561 tcaacaatta cgctatgttg tggccattgc caatagtggt actttccgtg aagctgctga
    31621 aaagatgtat gttagtcagc cgagtctgtc tatttctgtt cgtgatttgg aaaaagagtt
    31681 gggttttaag attttccgtc ggaccagctc agggactttc ttgacccgtc gtgggatgga
    31741 attttatgaa aaagcgcaag aattggttaa aggatttgat atttttcaaa atcagtatgc
    31801 caatcctgaa gaagaaaaag atgaattttc tgttgctagc cagcactatg acttcttgcc
    31861 accaactatt acggcctttt cagagcgcta tcctgactat aagaacttcc gtatttttga
    31921 atcaactact gttcaaatat tagatgaagt ggcgcaaggg catagtgaga ttgggattat
    31981 ctacctcaac aatcaaaata aaaaggggat tatgcaacgg gttgaaaaat taggtctgga
    32041 ggtcatcgaa ttgattcctt tccataccca tatttatctc cgtgagggtc atcctttagc
    32101 ccagaaagag gaattagtca tggaggattt agcggattta ccaacggttc gtttcactca
    32161 agagaaagac gagtaccttt attattcaga gaactttgtc gataccagcg ctagctcaca
    32221 gatgtttaat gtgacagacc gtgccacctt gaatggtatt ttggagcgga cggacgccta
    32281 tgcgacaggt tctggatttt tagatagtga cagtgttaat ggcattacag ttattcgtct
    32341 caaggataac ctagataacc gcatggtcta tgttaaacgt gaagaagtgg agcttagtca
    32401 agctgggact ctcttcgtag aagtcatgca agaatatttt gatcaaaaga ggaaatcatg
    32461 aaaaaaagag caatagtggc agtcattgta ctgcttttaa ttgggctgga tcagttggtc
    32521 aaatcctata tcgtccagca gattccactg ggtgaagtgc gctcctggat tcccaatttc
    32581 gttagcttga cctacctgca aaatcgaggt gcagcctttt ctatcttaca agatcagcag
    32641 ctgttattcg ctgtcattac tctggttgtc gtgataggtg ccatttggta tttacataaa
    32701 cacatggagg actcattctg gatggtcttg ggtttgactc taataatcgc gggtggtctt
    32761 ggaaacttta ttgacagggt cagtcagggc tttgttgtgg atatgttcca ccttgacttt
    32821 atcaactttg caattttcaa tgtggcagat agctatctga cggttggagt gattatttta
    32881 ttgattgcaa tactaaaaga ggaaataaat ggaaattaaa attgaaactg gtggtctgcg
    32941 tttggataag gctttgtcag atttgtcaga attatcacgt agtctcgcga atgaacaaat
    33001 taaatcaggc caggtcttgg tcaatggtca agtcaagaaa gctaaataca cagtccaaga
    33061 gggtgatgtc gtcacttacc atgtgccaga accagaggta ttagagtatg tggctgagga
    33121 tcttccgcta gaaatagtct accaagatga ggatgtggct gtcgttaaca aacctcaggg
    33181 aatggttgtg cacccgagtg ctggtcatac cagtggaacc ctagtaaatg ccctcatgta
    33241 tcatattaag gacttgtcgg gtatcaatgg ggttctgcgt ccagggattg ttcaccgtat
    33301 tgataaggat acgtcaggtc ttctcatgat tgctaaaaac gatgatgcgc atctagtact
    33361 tgcccaagaa ctcaaagata aaaagtctct ccgcaaatat tgggcgattg ttcatggaaa
    33421 tctgcctaat gatcgtggtg taattgaagc gccgattggc cggagtgaaa aagaccgtaa
    33481 gaaacaggct gtaactgcta aagggaagcc tgcagtgacg cgttttcacg tcttggaacg
    33541 ctttggcgat tatagcttag tagagttgca actggagaca gggcgcactc atcaaatccg
    33601 tgtccacatg gcttatatcg gccattcagt cgctggtgat gaggtctatg gtcctcgcaa
    33661 gactttgaaa ggacatggac aatttcttca tgccaagact ttaggtttta ctcatccgag
    33721 aacaggtaag accttggaat ttaaagcaga tatcccagag atttttaagg aaaccttgga
    33781 gagattgaga aagtaagaat gaaaaagaaa ttaactagtt tagcacttgt aggcgctttt
    33841 ttaggtttgt catggtatgg gaatgttcag gctcaagaaa gttcaggaaa taaaatccac
    33901 tttatcaatg ttcaagaagg tggcagtgat gcgattattc ttgaaagcaa tggacatttt
    33961 gccatggtgg atacaggaga agattatgat ttcccagatg gaagtgattc tcgctatcca
    34021 tggagagaag gaattgaaac gtcttataag catgttctaa cagaccgtgt ctttcgtcgt
    34081 ttgaaggaat tgggtgtcca aaaacttgat tttattttgg tgacccatac ccacagtgat
    34141 catattggaa atgttgatga attactgtct acctatccag ttgaccgagt ctatcttaag
    34201 aaatatagtg atagtcgtat tactaattct gaacgtctat gggataatct gtatggctat
    34261 gataaggttt tacagactgc tgcagaaaaa ggtgtttcag ttattcaaaa tatcacacaa
    34321 ggggatgctc attttcagtt tggggacatg gatattcagc tctataatta tgaaaatgaa
    34381 actgattcat cgggtgaatt aaagaaaatt tgggatgaca attccaattc cttgattagc
    34441 gtggtgaaag tcaatggcaa gaaaatttac cttgggggcg atttagataa tgttcatgga
    34501 gcagaagaca agtatggtcc tctcattgga aaagttgatt tgatgaagtt taatcatcac
    34561 catgatacca acaaatcaaa taccaaggat ttcattaaaa atttgagtcc gagtttgatt
    34621 gttcaaactt cggatagtct accttggaaa aatggtgttg atagtgagta tgttaattgg
    34681 ctcaaagaac gaggaattga gagaatcaat gcagccagca aagactatga tgcaacagtt
    34741 tttgatattc gacaagacgg tttagtaaac atttcaactt cctacaagcc gattccaagt
    34801 tttcaagctg gttggcataa gagttcatat ggaaactggt ggtatcaagc gcctgattct
    34861 acaggagaat atgctgtcgg ttggaatgaa attaagggtg aatggtatta ctttaaccaa
    34921 acgggtatct tattacagaa tcaatggaaa aaatggaaca atcgttggtt ctatttgaca
    34981 gactctggtg ttgctgctaa aaattggaag aaaatcgctg gaatctggta ttattttaac
    35041 aaagaaaacc agatggaaat tggttggatt caagataaag agcagtggta ttatttggat
    35101 gttgatggct ctatgaagac aggttggctt caatataagg ggcaatggta ttactttgct
    35161 ccatcagggg aaatgaaaac gggctgggta aaagataaag aagcctggta ctatatggat
    35221 tctactggta tcatgaagac aggtgagata gaagttgctg gacatcatta ctatctagaa
    35281 gaatcaggag ctatgaagca aggctggctt aaaaaggcaa atgattggta tttctacaag
    35341 acagatggtt cacgagctat aggttggatt aaagacaagg ataaatggta cttcttgaaa
    35401 gaaaatggtc aattacttgt gaatggtaag acaccagaag gctatactgt ggattcaagt
    35461 ggtgcctggt tagtggatgt tccgatcgag aaatctgcta caattaaaac tacaagtcat
    35521 tcagaaataa aagaatccaa agaagtagtg aaaaaggatc ttgaaaataa agaaacgagt
    35581 caacatgaaa gtgttacaaa ttcttcaact agtcaagatt tgacatcctc aacttcacaa
    35641 agctctgaaa cgagtgtaaa caaatcggaa tcagaacagt agtagaaaag aaggttttag
    35701 ggccttcttt ttcctatcaa ctcttttcta tttcctgtta ttcatgttat aatggataaa
    35761 tatgaataat cggagtgaga ctatgaaata caaacggatt gtctttaagg tgggtacttc
    35821 ttctctgaca aatgaggatg gaagtttatc acgtagtaag gtaaaggata ttacccagca
    35881 gttggctatg ctgcacgagg ctggtcatga gttgattttg gtgtcttcag gtgccattgc
    35941 ggctggtttt ggagccttag gatttaaaaa gcgtccgact aaaattgctg ataaacaggc
    36001 ttcagcagcg gtagggcagg gacttttgtt ggaagaatat acgaccaatc ttctcttgcg
    36061 tcaaatcgtt tctgcacaaa tcttgctgac ccaagatgac tttgtggata agcgtcgtta
    36121 taaaaatgcc catcaggctt tgtcggtttt gctcaaccgt ggggcaattc ctatcatcaa
    36181 tgagaatgat agtgtcgtta ttgatgagct caaggttggg gacaatgaca ctctaagtgc
    36241 tcaagtagcg gcgatggtcc aagcagacct tttagttttc ttgacagatg tggacggtct
    36301 ctatactgga aatcctaatt cagatccaag agccaaacgc ttggagagaa tcgagaccat
    36361 caatcgtgag attattgata tggctggtgg agctggttcg tcaaacggaa ctgggggtat
    36421 gttaaccaaa atcaaggctg caactatcgc gacggaatca ggagttcctg tttatatctg
    36481 ctcatccttg aaatcagatt ccatgattga ggcggcagag gagaccgagg atggttctta
    36541 ctttgttgct caagagaagg ggcttcgtac ccagaaacaa tggcttgcct tctatgctca
    36601 gagtcaaggt tctatttggg ttgataaagg ggctgcggaa gctctctctc aacatggaaa
    36661 gagtcttctc ttatctggta tcgttgaagc agaaggagtc ttttcttacg gtgatatcgt
    36721 gacagtattt gataaggaaa gtggaaaatc acttggaaaa ggacgcgtgc aatttggagc
    36781 atctgctttg gaggatatgt tgcgttctca aaaagccaag ggtgtcttga tttaccgtga
    36841 cgactggatt tccattactc ctgaaatcca actacttttt acagaatttt agaggtaaac
    36901 tatggtgagt agacaagaac aatttgaaca ggtacaggct gttaaaaaat cgattaacac
    36961 agctagtgaa gaagtgaaaa accaagcctt gctagccatg gctgatcact tagtggctgc
    37021 tactgaggaa attttagcgg ctaatgccct cgatatggca gcggctaagg ggaaaatctc
    37081 agatgtgatg ttggatcgtc tttatttgga tgcagatcgt atagaagcga tggcaagagg
    37141 aattcgtgaa gtggttgcct taccagatcc aatcggtgaa gttttagaaa caagtcagct
    37201 tgaaaatggt ttggttatca caaaaaaacg tgtagctatg ggtgtcatcg gtattatcta
    37261 tgaaagccgt ccaaatgtga cgtctgatgc ggctgctttg actcttaaga gtggaaatgc
    37321 ggttgttctt cgtagtggta aggatgccta tcaaacaacc catgccattg tcacagcctt
    37381 gaagaagggc ttggagacga ctactattca tccaaatgtg attcaactgg tggaggatac
    37441 tagccgtgaa agtagttatg ctatgatgaa ggccaagggc tatctagacc ttctcattcc
    37501 tcgtggagga gctggcttga tcaatgcagt ggttgagaat gcgattgtac ctgttatcga
    37561 gacagggact gggattgtcc atgtctatgt ggataaggat gcagacgaag acaaggcgct
    37621 gtctatcatc aacaatgcta aaaccagtcg tccttctgtt tgtaatgcca tggaggttct
    37681 gctggttcat gaaaacaagg cagcaagcat ccttcctcgc ttggatcaaa tgctggttgc
    37741 agatcgaaaa gaagctgggt tggaaccaat tcaattccgc ctagatagca aagcaagcca
    37801 gtttgtttca ggtcaagctg ctcaagcaca agactttgat accgagtttt tagactatat
    37861 tctagctgtt aaggttgtga gcagtttaga agaagcggtt gcgcatattg aatcccacag
    37921 tacccatcat tcggatgcta ttgtgacgga aaatgctgaa gctgcagcat actttacaga
    37981 tcaagtggac tctgcagcgg tgtatgttaa tgcctcaact cgtttcacag atggaggaca
    38041 atttggtctt ggttgtgaaa tggggatttc tactcagaaa ttgcacgcgc gtggtccaat
    38101 gggcttgaaa gagttgacca gctacaagta tgtggttgct ggtgatgggc agataaggga
    38161 gtaagagatg aagattggat ttatcggttt ggggaatatg ggtgctagct tggcaaaatc
    38221 tgtcttgcag actaggacgt cagatgagat tctccttgcc aatcgtagtc aagctaaggt
    38281 agatgctttc attgcagact ttggtggtca ggcttccagc aatgaagaaa tgtttgcaga
    38341 agcagatgtg atttttctag gagttaagcc tgctcagttt tctgaactgc tttctcaata
    38401 tcagaccatc cttgaaaaaa gagaaagtct tcttttgatt tcgatggcag ctggattgac
    38461 cttagaaaaa ctagcaagtc ttatcccaag ccaacaccga attattcgta tgatgcctaa
    38521 tacccctgct tctatcgggc aaggagtgat tagttatgcc ttgtctccta attgcagggc
    38581 tgaggacagt gagatctttt gtcagctttt agccaaggct ggtctcttgg ttgaattagg
    38641 agaaagctta atcaatgcag cgacaggtct tgcaggttgt ggaccagcct ttgtctatct
    38701 ctttattgag gccttggcag atgcaggtgt tcagacggga ttaccacgag aaacagcctt
    38761 gaaaatggca gcccaaactg tggtaggagc tgggcaattg gtcctagaaa gccagcaaca
    38821 tcctggagtt ttgaaagatc aagtttgtag tccaggcggt tcgactattg ctggcgtagc
    38881 aagcctagaa gcgcatgctt ttcgaggcac agtcatggag gcagttcatc aagcctataa
    38941 acgaacacaa gaactaggta aataagaggt agttttatct gcctctttta tggtggttga
    39001 tactcttcga aaatcaaatt caaactgcgt cagcttcacc ttgccgtact caagtacagc
    39061 ctgcggctag cttcctagtt tgctctttga ttttcattga gtatgaaatg agaagacaaa
    39121 aagattgtca caaaccccta tttttttgat agaatagaag tagtaaaaaa gaaatgagtt
    39181 agacatgtca aaaggatttt tagtctctct tgagggacca gagggagcag gcaagaccag
    39241 tgttttagag gctctgctac caattttaaa ggaaaaagga gtagaggtgt tgacgacccg
    39301 tgaacctggc ggagtcttga ttggggagaa gattcgggaa gtgattttgg atccaagtca
    39361 tactcagatg gatgctaaaa cagagctact tctctatatt gccagtcgca gacagcattt
    39421 ggtggaaaaa gttcttccag cccttgaagc tggcaagttg gtcatcatgg atcgttttat
    39481 cgatagttct gttgcctatc agggatttgg tcgtggctta gatattgaag ccattgactg
    39541 gctcaatcag tttgcgacag atggcctcaa acccgatttg acactctatt ttgacatcga
    39601 ggtggaagaa gggctggctc gtattgctgc gaatagtgac cgcgaggtta atcgtttgga
    39661 tttggaaggg ttggacttgc ataaaaaagt tcgtcaaggc tacctttctc ttctggataa
    39721 agagggaaat cgcattgtca agattgatgc tagtctccct ttggagcaag ttgtggaaac
    39781 taccaaggct gtcttgtttg acggaatggg cttggccaaa tgaaacaaga tcaactaaag
    39841 gcttggcaac cagctcagtt tgaccgtttt gtccgtatct tagaacaaga ccagctcaat
    39901 cacgcctatc tcttttcagg tttctttgga agcttggaaa tggcgcaatt tttagctaag
    39961 agcctctttt gtacggataa agttggcgtc ttaccatgtg agaaatgccg aagttgcaag
    40021 ctgattgaac aggaagagtt tccagatgtc accttgatta agccagtcaa tcaggtcatc
    40081 aagacagaac gcattcggga attggtggga cagttttctc aagcagggat tgaaagccag
    40141 caacaggtct ttattatcga gcaagcggat aaaatgcatc ccaacgcagc caattctctg
    40201 ctcaaggtca tcgaagaacc ccagagtgaa gtttatattt tcttcttgac tagcgatgag
    40261 gaaaagatgt taccgacaat ccgaagtcgg actcagatct tccactttaa aaagcaagaa
    40321 gaaaaactta tcttactctt agaacaaatg ggacttgtta agaaaaaagc gactctttta
    40381 gctaagttta gtcaatcgcg agctgaagca gaaaagttgg ctaatcaggc aagtttttgg
    40441 accttggtcg atgaaagtga acgcctgctg acttggttag tagctaagaa aaaagaaagt
    40501 tatctacagg ttgccaaatt agccaacttg gcagatgata aggaaaaaca ggatcaggtt
    40561 ttacggattc ttgaagttct ctgtgggcag gacctcttgc aggtaagagt aagagtgatt
    40621 ctacaagatt tactagaagc tagaaaaatg tggcaagcta atgtcagctt tcaaaatgcc
    40681 atggaatatc tggtcttgaa agaaatataa actcaaaaat gaatgataaa gaaaggaaag
    40741 ggctgtttta tggacaaaaa agaattattt gacgcgctgg atgatttttc ccaacaatta
    40801 ttggtaacct tagccgatgt ggaagccatc aagaaaaatc tcaagagctt ggtagaagaa
    40861 aatacagctc ttcgcttgga aaatagtaag ttgcgagaac gcttgggtga ggtggaagca
    40921 gacgctcccg tcaaggccaa gcatgttcgc gaaagtgtcc gtcgtattta ccgtgatgga
    40981 tttcacgtat gtaatgattt ttatggacaa cgtcgagagc aggacgaaga atgtatgttc
    41041 tgtgatgagt tgttatacag ggagtaagca tgcaaattca aaaaagtttt aaggggcagt
    41101 ctccctatgg caagctgtat ctagtggcaa cgccgattgg caatctagat gatatgactt
    41161 ttcgtgctat ccagaccttg aaagaagtgg actggattgc tgctgaggat acgcgcaata
    41221 cagggctttt gctcaagcat tttgacattt ccaccaagca gatcagtttt catgagcaca
    41281 atgccaagga aaaaattcct gatttgattg gtttcttgaa agcagggcaa agtattgctc
    41341 aggtctctga tgccggtttg cctagcattt cagaccctgg tcatgatttg gttaaggcag
    41401 ctattgagga agaaattgca gttgttacag ttccaggtgc ctctgcagga atttccgcct
    41461 tgattgccag tggtttagcg ccgcagccac atatctttta cggcttttta ccgagaaaat
    41521 caggccagca aaagcaattt ttcgactcga aaaaagacta tcctgaaact cagatttttt
    41581 atgaatcgcc ccatcgtgtg gcagatacat tggaaaatat gctagaagtc tacggtgacc
    41641 gctccgttgt cttggtcagg gaattgacca aaatctatga agaataccaa agaggtacaa
    41701 tttctgaatt gctggaaagc attgctgaaa cgtctctcaa gggtgaatgt cttctgattg
    41761 ttgaaggtgc cagtcaggat gtggaagaaa aaggcgagga agacttgttc ttagaaatcc
    41821 aagctcgtat tcagcaaggt atgaagaaaa atcaagctat taaggaagta gctaagattt
    41881 accagtggaa taagagtcaa ctctacgctg cctaccacga ctgggaagaa aaacaataaa
    41941 gggagacagg atgtaataat tctgtctgtt tctgtttaac ttaattagtg atgataatat
    42001 aaagatgtat cacttggtat agaagctttg gtattaagtt ttttattaag cccatacgga
    42061 ataccgatgg ttggagcagc agttatagcg ttcttagaag gtataaatag aaaaataagg
    42121 tcattttaaa tcaaaggatt gataaatcag aaagaaggtg attttttgcg aacatacgaa
    42181 aataaagaag aactaaaagc tgagatagag aaaacatttg agaaatatat tttagaattt
    42241 gataatattc cagaaaattt aaaagataag agagctgatg aagttgacag aactccagca
    42301 gaaaaccttg cttatcaggt tggttggacc aacttggttc ttaaatggga agaagatgaa
    42361 agaaaggggc ttcaagtaaa aacaccatcg gataaattta aatggaatca acttggtgaa
    42421 ttatatcagt ggttcacaga tacctacgct catttatctc tgcaagagtt gaaagcaaaa
    42481 ttaaatgaaa atattcattc tatctctgca atgattgatt cgttgagtga ggaagaatta
    42541 tttgaaccgc atatgagaaa gtgggctgat gaagcgacta aaacagcgac ttgggaagtg
    42601 tataagttta ttcatgtaaa tacggttgca ccttttggaa ctttcagaac taaaatcaga
    42661 aaatggaaga agatagtatt ataaattata tttttaactt taaaaaattt cataaaaatg
    42721 gttaccaaag gcgatagaag aaaaactatc gtctttttct ttgcaaattt ttaagaaggg
    42781 aggtgatctt gcatggactt tgaatatttt tataacagag aagcgaaaag atttaacttc
    42841 ttaaaagtac cggagatatt agttgataga gaagaatttc ggggcttatc agcagaagca
    42901 attatccttt attccatact tcttaaatag acaggaatgt catttaagaa taactggata
    42961 gacaaggaag gcagagtatt tatctatttt actgtcgaag aaattatgaa aagaagaaat
    43021 atctcaaagc caactgccat aaaaacatta gatgagcttg atataaaaaa aggaatagga
    43081 ctgatcgaaa gagtaaggct tggacttggt aagccgaaca tcatttatgt taaagacttt
    43141 atgagtatat ttcaggtaaa agaaaatgac ttacagaagt caaaaaactt aacttcagaa
    43201 gtaaaagatt ttaacctcag aagtaaagaa aatgaacttc aagaggttaa gaaccttgac
    43261 tctaactata tagagaataa taagagtaag tatagtaaga gagaatatag ttttggtgaa
    43321 aacggacttg gaacatttca aaatgtgttt ttagctgctg aagatatata ggatttacaa
    43381 atcataatga actcacagct tgagaattac attagacttc ctgcaaaact agaatcctag
    43441 ttcatgattg ataataccag caatcaaatt cattcgtaat ccgaa
//
LOCUS       DAVMJI010000018        42880 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.018, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000018 DAVMJI010000000
VERSION     DAVMJI010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42880
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.018"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(102..377)
                     /locus_tag="VYR58_001114"
     CDS             complement(102..377)
                     /locus_tag="VYR58_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV3622284.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(484..1323)
                     /locus_tag="VYR58_001115"
     CDS             complement(484..1323)
                     /locus_tag="VYR58_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV3622285.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1465..2313
                     /locus_tag="VYR58_001116"
     CDS             1465..2313
                     /locus_tag="VYR58_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV3622286.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2406..3323)
                     /locus_tag="VYR58_001117"
     CDS             complement(2406..3323)
                     /locus_tag="VYR58_001117"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV3622287.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3760..3965
                     /locus_tag="VYR58_001118"
                     /pseudo
     CDS             3760..3965
                     /locus_tag="VYR58_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4276..4569)
                     /gene="rpmA"
                     /locus_tag="VYR58_001119"
     CDS             complement(4276..4569)
                     /gene="rpmA"
                     /locus_tag="VYR58_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV3622288.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4586..4930)
                     /locus_tag="VYR58_001120"
     CDS             complement(4586..4930)
                     /locus_tag="VYR58_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV3622289.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4946..5260)
                     /gene="rplU"
                     /locus_tag="VYR58_001121"
     CDS             complement(4946..5260)
                     /gene="rplU"
                     /locus_tag="VYR58_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV3622290.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5296..5383)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5442..6146)
                     /locus_tag="VYR58_001122"
     CDS             complement(5442..6146)
                     /locus_tag="VYR58_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV3622291.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6548..6847
                     /locus_tag="VYR58_001123"
     CDS             6548..6847
                     /locus_tag="VYR58_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV3622292.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7029..8355
                     /locus_tag="VYR58_001124"
                     /pseudo
     CDS             7029..8355
                     /locus_tag="VYR58_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(8616..9590)
                     /gene="pta"
                     /locus_tag="VYR58_001125"
     CDS             complement(8616..9590)
                     /gene="pta"
                     /locus_tag="VYR58_001125"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV3622293.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(9634..10530)
                     /locus_tag="VYR58_001126"
     CDS             complement(9634..10530)
                     /locus_tag="VYR58_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV3622294.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(10527..11345)
                     /locus_tag="VYR58_001127"
     CDS             complement(10527..11345)
                     /locus_tag="VYR58_001127"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV3622295.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(11329..12000)
                     /locus_tag="VYR58_001128"
     CDS             complement(11329..12000)
                     /locus_tag="VYR58_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV3622296.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            12128..12697
                     /locus_tag="VYR58_001129"
     CDS             12128..12697
                     /locus_tag="VYR58_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV3622297.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            12810..13769
                     /locus_tag="VYR58_001130"
     CDS             12810..13769
                     /locus_tag="VYR58_001130"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV3622298.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            13779..14894
                     /locus_tag="VYR58_001131"
     CDS             13779..14894
                     /locus_tag="VYR58_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV3622299.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            14899..15246
                     /locus_tag="VYR58_001132"
     CDS             14899..15246
                     /locus_tag="VYR58_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV3622300.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            15254..15469
                     /locus_tag="VYR58_001133"
     CDS             15254..15469
                     /locus_tag="VYR58_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV3622301.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            15552..16193
                     /locus_tag="VYR58_001134"
     CDS             15552..16193
                     /locus_tag="VYR58_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV3622302.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            16211..16900
                     /locus_tag="VYR58_001135"
     CDS             16211..16900
                     /locus_tag="VYR58_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV3622303.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(16897..17577)
                     /gene="radC"
                     /locus_tag="VYR58_001136"
     CDS             complement(16897..17577)
                     /gene="radC"
                     /locus_tag="VYR58_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV3622304.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(17620..19911)
                     /gene="pcrA"
                     /locus_tag="VYR58_001137"
     CDS             complement(17620..19911)
                     /gene="pcrA"
                     /locus_tag="VYR58_001137"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV3622305.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(20102..20908)
                     /locus_tag="VYR58_001138"
                     /pseudo
     CDS             complement(20102..20908)
                     /locus_tag="VYR58_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004897104.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(21289..22149)
                     /locus_tag="VYR58_001139"
     CDS             complement(21289..22149)
                     /locus_tag="VYR58_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV3622306.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(22165..23442)
                     /locus_tag="VYR58_001140"
     CDS             complement(22165..23442)
                     /locus_tag="VYR58_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV3622307.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFWVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(23435..23986)
                     /locus_tag="VYR58_001141"
     CDS             complement(23435..23986)
                     /locus_tag="VYR58_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622308.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(24002..25261)
                     /locus_tag="VYR58_001142"
     CDS             complement(24002..25261)
                     /locus_tag="VYR58_001142"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV3622309.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(26348..26506)
                     /locus_tag="VYR58_001143"
     CDS             complement(26348..26506)
                     /locus_tag="VYR58_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622310.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(26516..27826)
                     /gene="obgE"
                     /locus_tag="VYR58_001144"
     CDS             complement(26516..27826)
                     /gene="obgE"
                     /locus_tag="VYR58_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV3622311.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(27890..28024)
                     /locus_tag="VYR58_001145"
     CDS             complement(27890..28024)
                     /locus_tag="VYR58_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV3622312.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(28083..28259)
                     /locus_tag="VYR58_001146"
     CDS             complement(28083..28259)
                     /locus_tag="VYR58_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV3622313.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(28290..29615)
                     /locus_tag="VYR58_001147"
     CDS             complement(28290..29615)
                     /locus_tag="VYR58_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV3622314.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(29631..30674)
                     /gene="cpoA"
                     /locus_tag="VYR58_001148"
     CDS             complement(29631..30674)
                     /gene="cpoA"
                     /locus_tag="VYR58_001148"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV3622315.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(30789..31118)
                     /locus_tag="VYR58_001149"
     CDS             complement(30789..31118)
                     /locus_tag="VYR58_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV3622316.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(31132..32241)
                     /gene="rpoD"
                     /locus_tag="VYR58_001150"
     CDS             complement(31132..32241)
                     /gene="rpoD"
                     /locus_tag="VYR58_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV3622317.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(32244..34004)
                     /gene="dnaG"
                     /locus_tag="VYR58_001151"
     CDS             complement(32244..34004)
                     /gene="dnaG"
                     /locus_tag="VYR58_001151"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV3622318.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRAGI
                     ESAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(34094..34852)
                     /locus_tag="VYR58_001152"
     CDS             complement(34094..34852)
                     /locus_tag="VYR58_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622319.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(34849..35715)
                     /locus_tag="VYR58_001153"
     CDS             complement(34849..35715)
                     /locus_tag="VYR58_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622320.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKILTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(35784..36788)
                     /locus_tag="VYR58_001154"
     CDS             complement(35784..36788)
                     /locus_tag="VYR58_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV3622321.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(36901..37118)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(37201..39897)
                     /gene="ppc"
                     /locus_tag="VYR58_001155"
     CDS             complement(37201..39897)
                     /gene="ppc"
                     /locus_tag="VYR58_001155"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV3622322.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(39917..41146)
                     /locus_tag="VYR58_001156"
     CDS             complement(39917..41146)
                     /locus_tag="VYR58_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV3622323.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFAGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(41274..41527)
                     /locus_tag="VYR58_001157"
                     /pseudo
     CDS             complement(41274..41527)
                     /locus_tag="VYR58_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(42044..42265)
                     /locus_tag="VYR58_001158"
     CDS             complement(42044..42265)
                     /locus_tag="VYR58_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3622324.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
BASE COUNT        12995 a         9298 c         7549 g        13038 t
ORIGIN      
        1 gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa gcctactgac
       61 caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac agcgtcttta
      121 agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat ttctttacca
      181 gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt accaaaaccg
      241 atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa tacagcttca
      301 actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt agcgatcaaa
      361 tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac aaatataatc
      421 atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat tttatttatt
      481 tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt gagtttgaat
      541 aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta agctttcttt
      601 catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg ctacagcacg
      661 ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag ttccacgacc
      721 tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga tattgagaag
      781 agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat tttccaaagt
      841 tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag ataaaattgc
      901 ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga atttcagggc
      961 ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc tagcaccttg
     1021 gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa gaatctggcc
     1081 accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg gctgacttgt
     1141 tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt ctttcaaatc
     1201 cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg taatatctaa
     1261 ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct taatttttgt
     1321 catagtatca atctttctat tttaggattc agattggttt ccttacttct aattatatca
     1381 aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt tgatataatc
     1441 aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt taccatttta
     1501 ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca tcatctcttt
     1561 gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat ccctgtttcc
     1621 ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaagat ctttggagcc
     1681 aaatccctct attctagttt actaggaacc ttagctttgt ccgcctggtt agcttttttt
     1741 gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc ccttatagcg
     1801 ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac aactggcgga
     1861 actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg aaaactgctc
     1921 tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga tttgagattg
     1981 gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt gattggtgaa
     2041 ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca acttgctaag
     2101 gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg ctactatagt
     2161 aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt gaaaacgaag
     2221 gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc ccatgaaatc
     2281 ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg acctcaaaag
     2341 ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt tatttactca
     2401 agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc cactaattgg
     2461 tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac catgacggtt
     2521 tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc ttcttctcca
     2581 tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct ttgaatctca
     2641 acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag cactaaattc
     2701 gctgtcggat aaccaattgt acgaccacga gcattaccat gaaccaccat acctcttgat
     2761 ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa aatagcttga
     2821 cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac aatgataact
     2881 tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc aaatgtataa
     2941 tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc aaagaattct
     3001 tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc ttctacacct
     3061 tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa caaatctgga
     3121 tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac gataggcaat
     3181 aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc cttatgtatg
     3241 ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc tttttggttt
     3301 tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta tttctggaac
     3361 agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa aagcacttta
     3421 ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg taggacatct
     3481 tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc atactatgtt
     3541 atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat tggtgccaaa
     3601 aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa tgagacaact
     3661 tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc actttccctg
     3721 atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt ccaacaactc
     3781 ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt ggattctcag
     3841 accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa accattcaga
     3901 caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat agtcaattga
     3961 aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt gttctattcc
     4021 agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag gctgtacttg
     4081 agtacggcaa ggtgaaattg acgtggtttg aatttgattt tcgaagagta tcaatccact
     4141 atacatatta aaaagtatgg gtatcaaaat aaaaaaacag gctctccgaa aactcggaaa
     4201 gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc gggataaaag
     4261 gttcaatgaa cctttttatt ttgcgattgg gtaaacagaa acttgttttt tatcgcgtcc
     4321 tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt ctccaccacg
     4381 accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga ttgatccacc
     4441 tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg aatcacgtcc
     4501 gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt taagagtcat
     4561 ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt tggacgaact
     4621 cagaatagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag aataactggg
     4681 tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga tagccacctt
     4741 catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata gaattgataa
     4801 agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat tcgccactct
     4861 cggcgtgtcc agtaatttcc gcactcctca gctcgccatc ttcggctctc tcaaagactg
     4921 cctgtatcat gtgttctcct taaaattaag cgttgattgc gttgatgaca acttttgtat
     4981 atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac ttgtaagtaa
     5041 ccactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct ccagcaacaa
     5101 gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta aaagtaactt
     5161 cttgaccagc ttcaacgttc aatttttcaa cgtaaactgc ttgaccaact tcaactttaa
     5221 cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc ctatgatttt
     5281 tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacga accacttaaa
     5341 cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata gtcaactctt
     5401 caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatga agctttttct
     5461 tttacttttt tctgccaaga ggcaaaaagc atgctgaggt aaaaaacgct catcataata
     5521 ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga aaagacaacg
     5581 ccaaggacaa aactactaag caggctaaca aatatgaatc cttcacgcaa aaaaggagtg
     5641 tgcttggttc ggaaataatc tccaaaagcc agcatggtcc gtttgatatt ccctgtcata
     5701 aaagcgttat tataggcaat acccgacact tctccaaaag cagttgtcac cagtcccata
     5761 cagaaggcca agggcggcac tagatagata ttatccacag tttgcggcac aaaagcaata
     5821 atgattgata agattgccaa gggaatcaag gacagaatag gttttttcac aattctcaat
     5881 ttttccttat aaatcgttaa taaaaagact cccatcataa acgctagcaa ggtgagaacc
     5941 ttgtccctaa catccgaaac attattttta attaattcta ctgaaagaaa gacaacattt
     6001 ccagtttgtc cagctacaag ggtattcccg cgaacaataa aagtgtaagc atccacatat
     6061 ccagcacaaa acgtcaaaaa aagtgctaac cttttagact gacgtgatat ttttcttata
     6121 ggtaataacc tcattttacc tcccattgta ttttctctta gaaatattgt accattttct
     6181 ttctaaaaaa tcgtaggcta ccatttagat tttactatta gcataaaaat aataatagac
     6241 aactatttat ccaaaaatag atagatgtaa catgtttgca aacaaagcat acgaaccttt
     6301 agtaaaatca tttccatgaa actagaatag agccctctta gcaaaaatca ttattttaat
     6361 ttatttctaa tcactccttg acataaataa ctctcaccaa taaaagacta tgtcttaaaa
     6421 aaatggtata ataaaatcaa tacttgggct tgatggctat gctactaata acaattagga
     6481 gagaaaatca ggcacttgtt aacaacaagg attatcccct tgagatgaaa ggaactttag
     6541 aaatcttatg atgaacatgc aaaacatgat gcgtcaagca caaaaacttc aaaaacaaat
     6601 ggaacaaagc caagctgaac ttgctgctat gcaatttgtt ggcaaatctg ctcaagatct
     6661 tgtccaagcg accttaactg gcgataagaa agttgtcagc attgatttca atccagctgt
     6721 cgttgaccca gaggaccttg agactctttc tgatatgacc gttcaagcca tcaactctgc
     6781 tcttgaacaa atcgatgaaa ctaccaagaa aaaactgggt gctttcgctg ggaaattacc
     6841 tttctaaaaa caaggagcta gaacaatgct tgtcgataac aaaggctaag aaaggtgcaa
     6901 aaatgactct ataatatttg tagtgggtaa atccactata gatattatgg agcctatttt
     6961 attgtagaaa aaaagtccca taagatctat aatgaaaagc gaccaaacaa ctcattagaa
     7021 agattcatat ggaacaatta cattttatca caaaattact agacattaaa gaccctaata
     7081 tccagatttt agacatcatc aataaggata cacacaagga aatcatcgcc aaactggact
     7141 acgacgcccc atcttgccct gagtgcggaa atcaattgaa gaaatatgac tttcaaaaac
     7201 cttctaaaat tccttatctt gaaacgactg gtatgcctac tagaattctc cttagaaaac
     7261 gccgtttcaa gtgctatcac tgttcaaaaa tgatggttgc tgagactccc ctggtaaaga
     7321 aaaatcacca aatccctcgt atcatcaacc aaaaaattgc tcaaaagtta attgaaaaaa
     7381 tttctatgac tgatattgcc catcagctgg ccatttcaac ttcaactgtc attcgcaagc
     7441 tcaatgactt ccactttgag tgtaatttta gaaatctgcc tgagattatg tcttgggagg
     7501 ttgaaacagt ccggggagtg actgtttcaa tcgggagatg gagatgagct tcattgcgca
     7561 agattttgaa aagctcgata ttatcactgt tcttgagggt agaacacaag ctatcattcg
     7621 aaatcacttt cttcgctacg atagagttgt ccgatgtcgc gtcaaaatta ttactatgga
     7681 tatgtttagt ccttactatg acttggctaa acagcttcgc tttcaaattt ctaggctcag
     7741 gctgaaacag tctcccagac tgtttcactc ccgaatgcta aaatcgttct tgatcgcttt
     7801 catattgtac aacatcttag ccgtgctatg agtcgtgtgc gtgtccaaat catgaatcag
     7861 tttcatcgaa aatcccatga atacaaggct atcaagcgct actggaaact cattcaacag
     7921 gatagccgta aactcagcga taaacatttt tatcgcccta cttttcgtat gcatttaacc
     7981 aataaagaga ttttagacaa gcttttgagc tattcacaag acttgaaaca tcactatcag
     8041 ctctatcaac tcttgctgtt tcactttcag aataaggaac cagagaaatt tttcggactt
     8101 attgaggaca atcttaagca ggttcatcct atttttcaga ctgtctttaa aacctttcta
     8161 aaggacaaag agaaaatcgt caacgccctt caactaccct attcaaacgc caaattggaa
     8221 gcgaccaata atctcatcaa acttatcaag cgcaatgcct ttggttttcg gaactttgaa
     8281 aacttcaaaa aacggatttt tatcgctctg aatatcaaaa aagaaaggac aaaatttgtc
     8341 ctttctcgag cttagctgac ttcaacccac tacagttgac aaagagccaa aaaattctct
     8401 tttcatactc atttaaaatc aaaaagggaa tttatcgttt tacggatatg tatattacag
     8461 atttctatag gtcgtgtata gacaggatat catcgcttgg aagttttcct ttttgacacc
     8521 aatcagtaat ttagttctca ggaattaatg gcagtgcttt tcgtacatag tttcataact
     8581 acagtatagc atagtatatc actttatagt tttcactatt gatgaactgc ttgagctgct
     8641 gtgatgaggg tcaacttgta aacatcatct gcattacatc cacgagaaag atcattaact
     8701 ggcttgttta aaccttgcaa aacaggtcct acagccgcaa agccacccag gcgttcagcc
     8761 atcttgtaac cgatatttcc tgcctcgata cctgggaaga tgaagacatt tgcttgacca
     8821 gctactgtac ttcccggagc tttcagagct gcagtttcgg gaacaaaggc cgcatcaaat
     8881 tgcaactcac catcgatttc aaggtcagga cgcaagtcgt gagcaatttt agttgcttca
     8941 acgaccttat caacgctttc accaaaccct gaacctttag tagaatagct caacatggca
     9001 attttaggtt cgatgccaaa catcttagct gtgattgctg agttgatggc aatttcagcc
     9061 aaggcttctg catctggatt gatattaatg gcacagtctc caaataggta acgttccgta
     9121 ccacgaacca tgaggaaggc tcctgaagta cgagttacat ttggacgagt tttgatgatt
     9181 tgtagagctg ggcgaactgt tgaagctgtt gagtgaatcg ctcctgacac cattccatca
     9241 accaagccca agtaaaccaa catcacacca aagtagttga catcttcaac caaaaccttg
     9301 cgtacatctt cttcagtcat tttgcccttg cgacgctcca ccaaggcaga aaccatttct
     9361 tcaaattgag gataatgttg agggtcgatg acctcataac catccatgat tccttcaatt
     9421 tcaagataaa ttttaatttt ttcaggattt ccaagcaaaa caggaatcac ttctgtttct
     9481 tttactaagc gttttgttgc ttgaagaata cgaggctctt ccccttcagg gagaacgata
     9541 cgagcatttt taccaacaag gttggctttg agactttcaa aaacttccat gagttttctc
     9601 ctttaagata ataattatac tctgagacag tttttataga gtattagttg ataactgggt
     9661 aataaggtta ctgaaatcat ccggcaaggg actttctaac tgcaagtctt gctctaaaaa
     9721 tggatgataa aaggataggt aatggcaatg cagagcctga cgttgaatac catcttccag
     9781 actaccacca tacaaatcat ctcccagcaa aggaaaaccg atatgagaaa aatggactcg
     9841 gatttgatgg gttcgaccag tgtgcaggtg aatatagacc aagtgaatat ttccataaga
     9901 agctacaatc ttgtatgaag tatgggcata ctttccgcct ttagccactc gtctggtaat
     9961 aatggaatct tcatcacgcg caatcggagc aataatttcc ccttctggtt ccaaatgtcc
    10021 atctccctta accaaagcaa agtagcgttt ctcgatagat ttcttctgca actgcttgtc
    10081 taatcgtgca tgggcataac cgtgcttggc aaagagcatc aagccagaag tgtccctatc
    10141 tagtctggta acaatgtgaa cctgctgatt ttcataattt tgcttgacat agtaaccctt
    10201 gataaaattg gcaatggtat tagagtgatt aacactagga atagaagcca ctccataggg
    10261 tttattcaag actagaaagt ggtcatcctc atagagaata tctaatggaa gctcaatagc
    10321 ctccaaggtt tcaaagcctt tctcagcggg aatgtcaatg gtaacgtagt ctccaacgtc
    10381 caatagatac gttgcatttt gcggttgatt attgaccaga atagctccac ctcgaaactt
    10441 aatcttggcc agcaatccct tagaaacctc gtgctttttt aagaaggtct taaccttgac
    10501 atgttcatct gcgataaatt caaacctcat tcatccacct caccgataaa ggcatcctta
    10561 acacggttcc agaaactggt atggctagga gtcgcgacaa agtgaatctt atgatgggcg
    10621 atttgatact caatacgctc aatattacgg aaagaataaa cgctattgtc aaccgaaata
    10681 gtatgataat cgtttcttgt tggaataagt tcaatcttat ccttcttagg cacaataatg
    10741 gaagagccca gtgttcgata gacacgatta ttaaggctgg caatttccgt taattgcaaa
    10801 gcttcaatgg tagggtgtaa aacagcaccg ccaagagact tgttataggc agtactacca
    10861 gtcggtgtcg aaactgttag cccgtctcca cgaaaacgtt caaagggaac accatttatt
    10921 acaatatctg ccaccatggt tcgatcagac ctgcggatgc tggcttcgtt gagtgctctg
    10981 aaaatcttaa cttcaccatt ttcaagaaag accttcacat tcagaacagg gtaagaaacc
    11041 cttgccccag tatctagctg caaattagtc actagcttgt ccaactcaaa atcacgataa
    11101 tctgtataga agcccaaatg tccagtgtga agaccgataa agcggacctt ctcaagctga
    11161 ttttcgtact tatgaaaggc cgacaagagc ataccatccc cgccaatgga aatgacaata
    11221 tccggattgg tatcattgag tataaactga tttctcttca aacgatctcg caattcatac
    11281 aaaacccttt gactctgcgg ttttctattg gctatcagat caattcgttt acctgtattc
    11341 ttcatctgta tcgtcactgt ttcctacacc gtcatttaat tttctactca aaggatcaaa
    11401 aagtgcctga gcttcttgga tatcatcacg aatttcaccc atttcttcat ccaactgatg
    11461 ggcgattcta gctgtaattt ccagtcgctt cttaatctca tctgggaaat ccccttggta
    11521 cttgtagttg agagaatgtt ctatcgttgc ccagaaattc atggccaaag tacgaatttg
    11581 aatttctgcc aaaatagtct taactccatt gatggtatca accgtatatt ctactaccac
    11641 atgataggaa cgatagcctg atgcttttct atgagtaatg taatctcgct cctgtatgat
    11701 tcgcatatcc tgacgcttgt gcaaaatatc cactacttcc ttgacgtcat ctacaaactg
    11761 aaccatcaca cgtaagccag caatatcctg caaatcgtgt tccaaggtcg cataagtaat
    11821 gccacgacga gccatttttt ctttgatgct ctcaattggc ttaactcgac cggtcacaaa
    11881 ctcaattgga gaatgcttat tttgcttacg atattgctta cgaataccac gaagtttaat
    11941 ctttaactca ccaacagctt gaatgtaagg atctagaaat tcttcccatt ctaaggtcat
    12001 atattctccc ttgttctcat attatccgtc aaaaatatct ttgatttttt ctccagattc
    12061 atatacaata aatacaatgc ttattatacc ataaatccgc tttcaacgat aaaaaaaggt
    12121 aagaaaaatg aaacatttag aaattgaatt gaaaacacta ttgaaaaaag atgaatacaa
    12181 tcgtctaaaa gaccagttca caggtgtcac tcctgttctt caaacaaatt actacatcga
    12241 cacgcctgat tttgaactgc gagaaaagaa agtcgctatg cgcattcgaa cctttgaaga
    12301 ctgggctgag ttgacactca aagtcccgca gagtgttgga aacatggaat acaaccaaaa
    12361 attgcaacta aaagatgctg agaactatct gagtaaggaa gaacttcctc aagggctagt
    12421 actggatgaa ttggcgaaac atggtatcca aagtaagaac tggcaggttc ttggttgtct
    12481 aacaacgctt cgctatgaaa tgaaaacagc tattggtctc atggcactgg atcagagccg
    12541 atactttgat ataacagatt acgaattgga gcttgaagtg gaaaatcatg agcaaggcaa
    12601 acaggatttc cgacaatttt tagagaaaaa tcagatttcc taccaaaaag ctccttcaaa
    12661 attggttcga tttgtcaaaa gtatgaaaaa tagctgaaat aatctccatt ttttggtaaa
    12721 atagaaaaga taaaaataca caaatcccag ttcatatatg taaggtaaat ataactagga
    12781 tttataaagt ttacagagga cggtctataa tgtcagatag aaaaaacatg aaacttttcg
    12841 cactcaactc taaccaagag attgcacaaa aaattgccca agctgttggt gtcccacttg
    12901 gaaaactatc atcacgtcaa ttttcagacg gagaaatcca agtaaatatc gaagaaagtg
    12961 tccgtggtta tgatgtttac atcatccaat caacaagttt ccctgtcaac aaccacctaa
    13021 tggaattgtt aatcatggtc gatgcttgtg tgcgtgcaag tgcccacagt atcaacgttg
    13081 tccttccata ttttggctat gcacgtcaag accgcattgc ttgtcctcgt gagccactta
    13141 cagcaaaact agttgccaat atgctggtta aggctggagt tgatcgtatc ctgactcttg
    13201 atttgcatgc cgttcaggtt caaggtttct ttgatattcc agtggataat cttttcactg
    13261 ttcccctatt cgcaaaacat tactgcgata aaggattgct tggttcagat gttgttgtcg
    13321 ttagccctaa aaattcaggt gtcaaacgtg cgcgtagcct ggctgaatat cttgatgctc
    13381 ctatcgccat tatcgactac cctcaagacg atgcaactcg taacgaaggt tatattattg
    13441 gtgatgttga aggtaagaaa gctatcttga ttgatgatat tttaaataca ggacgtacct
    13501 tctctgaagc ttctaaaatc gttgaacgtg aaggagctac agaaatttat gctgtttcta
    13561 gccacggtct cttcgtcgag ggagctgctg agcttcttga caatactaat attaaagaaa
    13621 ttcttgtgac tgattcagta gcaacaaaag aaaaaactcc taaaaatgta tgctacatca
    13681 ctgctagtga gttaattggt gatgctatcg tccgtattca cgaaagaaaa ccagtcagcc
    13741 cactctttgc ctacaataaa aagaaataag gtgattcttt gatttatttg gacaatgctg
    13801 caacgactcc tatgtcagca gttgctattt cagctatgac caaggttatg caagaaaccc
    13861 acggaaatcc ttctagtatt catggtcatg gtcgtcaagc tggcaaactc ttgcgagaag
    13921 cccgtcagga actagcccag ttactaagga caaaacctca acatatcttt ttcacttctg
    13981 gtgggactga aggcaataat actaccatca ttggctactg tcttcgtcac caagaacaag
    14041 gaaaacatat catcacaact gccatcgagc accatgctgt ccttgaaaca attgattact
    14101 tggttcaaca ctttgggttt gaagcaacca ttatccagcc agaaaatcaa gaaatcacag
    14161 cccagcaaat tcaaaaggct ttacgtgacg atacgatttt ggtttctacc atgtttgcca
    14221 ataatgagac aggaaaccta ctgcccatcg ctgaaattgg ccaaatactc aagcaacacc
    14281 ctgctgccta tcatgttgat gcagttcagg ctattggtaa aatcccaatt cattcagaag
    14341 aattgggcat tgattttctc actgcttctg cccacaaatt ccatggtcct aagggaatcg
    14401 gttttctcta cgcatctagc atggactttg attcctatct acatggcgga gaccaggaac
    14461 agaaaaaacg tgcaggaact gaaaatctgc ctgctatcgt aggcatggtt gcagccctaa
    14521 aagaagacct agaaaaacaa gaagaacatt ttcaacatgt acaaaatcta gaaactgcct
    14581 ttctggcaga gctggagggc attcagtatt acttgaatag aggaaaacat catctccctt
    14641 atgttctcaa tattggattt cctggtcaga aaaatgacct cttactcctt cggctagatt
    14701 tagctggaat ttcaatctct actggctcag cctgtactgc aggcgttgtc caatccagcc
    14761 atgttcttga agccatgtat ggcgcaaatt cagaacgctt gaaggaatcc cttcgcatca
    14821 gtttgtcgcc acaaaatacc gttgaagacc tacaaaccct cgcaaaaacc ttaaaagaaa
    14881 ttatcggagg ttagccatat ggcatttgaa aaaatcattc agttaaaaaa ttgtcgttac
    14941 gattacactc ttagcccttc tgttaaaaaa ttcaccctca aagataacac cttttttgaa
    15001 actaaggttg gtaactatga actgactcgc cttttggaaa aagtgccaaa cagcggtgaa
    15061 ggcttccaac tcaaaatcat cattaacaag gaacttacag gggctaaaat caatatcact
    15121 gacaagtttg gccttcgtct agttgatatt ttcaaatcag aagaccacca tattcatcag
    15181 gaaaaattct acttcctcat ggatagcttg gtagaacgtg gtgtctttac aaaatcggaa
    15241 agatagagcc aaaatgtttg aactgaccta taaggactgc tatcatgtag agcgtactct
    15301 caagtatgag gatcatgagg ctctcatgtt gactttgtca ggatgtgtaa ccttaccaga
    15361 tacactttat gtgacttctc tgacttttag gggccaaaaa gtttatcagg gtctggtcgg
    15421 agacctctac cgttttctat ctcatgcaga ttttttacat caaaactaag atttttctta
    15481 gttttttctt atttttgttg attttttcac aatgtttcta taaaatagaa gaatagaaag
    15541 gttgtgattt tgtgaaagat aaacagtttg ctattccaaa agctacagca aaaagactct
    15601 ctctctacta tcgaattttt aagagatttc atgcagaaaa gattgaacgt gccaactcta
    15661 agcaaattgc agaggctatc ggtattgatt cagcgaccgt acgtcgtgat ttttcctatt
    15721 ttggtgaact tggtcgtcgt ggttttggct atgatgtcaa aaaactaatg acattttttg
    15781 ccgatttgct caatgacaac tctattacca atgtcatgct ggttggtatt ggaaatatgg
    15841 gccatgccct tctccactac cgcttccacg aacgtaacaa gatgaagatt atcatggcct
    15901 ttgacctaga cgaccatcct gaagtcggta cccaaactcc tgacgggatt cccatttacg
    15961 ggatttctca gatcaaggat aaaatcaagg atgctgatgt gaagactgct atcctaactg
    16021 ttcccagcgt caagtcacaa gaggttgcta atctcttggt tgatgctggt gtgaaaggaa
    16081 ttctcagttt ttcaccagtc catctgcatt taccaaaaga cgtggtcgtt cagtatgtcg
    16141 atttgacaag tgaactccaa accctcctct acttcatgcg aaaagaggat tagaaagcga
    16201 aaatcatttt atgaaaaaac cagttattgg gattacagga aacgaaaaaa ctcatccaga
    16261 tgatgacatc atgatgagct acgcagcaaa aggctttgtt gaaggcgtta aagatgctgg
    16321 agggattcct atcatcctac cgattggtga tcaagaaatg gcctgccact atatcagttt
    16381 gattgacaag ctcatcttga caggtgggca aaatgtcgat ccaaaattct atggcgaacc
    16441 caaaaccatt gatagcgatg attatcacct tcaaagagat atcttcgaac tggccctcat
    16501 caaggaagct attaaacaga aaaagcccat tttctctgtc tgccgtggta cccaactctt
    16561 taacgttgcc atgggtggaa ctttgtacca agatatcgaa gaccattggc aggattcttc
    16621 tgttgagtac acaactcaac gcttggtaac agaaccagat accgttctcc aagaaatcta
    16681 tggagaaatc tctcatatca actccttcca ccaccagagc atcaaggact tagcaccaaa
    16741 tttaaaagtt gtggctcatg atcctaaaga tggtatcatt gaggctgtca tgagtacgga
    16801 tgatgtcgcc tttctcggtg tccaatggca tccagaactt ctttttgaaa atcgtcccaa
    16861 agataagaaa ctctttgact atgtcgttaa tgaactttag attaaatctg tcttttcacg
    16921 ataactaaag taattagaat gagagacaat caaatggtcc aagagaacaa tccccatcag
    16981 ttcgcaggct tctttaacaa gtttagtgac atgatcatca ttttggctag gcgctaccgc
    17041 tcctgaagga tgattgtgga ccaagataag agaagtcgcc atatgcttga ttgcatagtg
    17101 aagaatctct cgcggttcag cgatactacg agttacagaa ccgataaaaa tggtctgctg
    17161 atggatgatt tgattttgag tattgagata gagtgccacc aggtgctctt gttttttatc
    17221 ccctaattcc tgctgcatct tcttggccaa cttttgactg ctgagaatac tttccatttc
    17281 aagagtctcg tgtttgtgaa tacgatgccc cagttcaatc atagcttgta attctatggc
    17341 cttaacacgc ccaataccag acaaactctg caattcctgc agggtcattt ttttcaaatc
    17401 cgttaggctt gaaagattgt tcaagacttt ttgggcaatt tcaaaaacgc tagcttgacg
    17461 tgttcctgtc ctgagtaaaa tagctagcaa ctcttggtta ctaagcgctt caactccttc
    17521 cttggccagc ctttctcttg gtaatagtga atcttcttgg aatgaaatac tgtacataaa
    17581 aatcctcctc actttattat tcgtgagaag gatggaaaat tagatttttt tctcaattgg
    17641 agccacactg gctaaaagtt ttttcaaacc tacttctggg aaattgattt tcaattcctg
    17701 cctagcaccg ctacctgaaa cttccagaac agttccctct ccccatttct tgtggagagc
    17761 aatgtcacca atggaccaat ttgcctcgct agatgctgat tttgcgccag ctgtaaattg
    17821 accaaatgga agaccgcttg actggattga ttttggggca gcaccgcgtt tacggtcttg
    17881 aagagcctga gccaaactca taccttgacc aaaggaaata ctaccactgc tatatgatgc
    17941 cttaaagctt gtatttgcag gacgagccag accttgatac tcaagcaagt ctgaactgat
    18001 ttcgttaata aaacgagtcg gacggttata attggtacga ccaaaaagca agcgtgagtt
    18061 ggcattggtc agatagagaa ttttctctgc acgcgtgata cctacatagg ctagacggcg
    18121 ctcttcttct aattcatctg gatcttcagt cgcacgacta agtggaaaga cattttcttc
    18181 catcccaatc aaaaagacaa ctggaaattc gagacctttg gcagcatgca gggtcatcaa
    18241 ggtcacttct gatgtctcct gactacctga atctgtgtcg gcaatcaaag ccaagtcatt
    18301 taagaaacga ctcagtttgt ccagaccagt ttcctcttct gtcacatcag tggtgtcatc
    18361 aaagttcttc gtaacagaaa gaaactcttc gatattttca acccgtgcct tgctttctag
    18421 agtcgcttgg gcgttaagaa tatcgacata acctgttttt tctaggacgg actcaaccaa
    18481 ctctgtaatg cttaagtggt ctagctgctc ccgcaaatca agcatcatat tggcaaaatc
    18541 ccagatagat tgggctgcct tacccttgat accagacaac ataatattag cagaagcatc
    18601 cagcatagac atattttgca aatttgcaaa atcacggatt ttctcaactg tacctggacc
    18661 aattccacgt ttaggctcgt tgataatacg ctcaaaacta atattgtcac tcaaattagc
    18721 aataaggttg agataagcaa taatatcgcg aatttcctta cggctgtaga atttggttcc
    18781 gccaaccatg gtataaggaa tgttagactt gagcagggct tcctcaattg tacgggactg
    18841 ggcattagtc cgatagagaa ctgcaaaatc cttatgaagg aagttttgac tgcgactaag
    18901 ttcatcgatg gttctggcta caaatacagc ctcatccagc tcatcatcgg cacgatagta
    18961 aacgatttgc tccccatcag cgttttgagt ccagagattt ttaggacggc gatttttatt
    19021 gtttttaata acctcgttgg ccgcttggag aatggttttg gttgagcggt aattttcctc
    19081 caacaaaaca accttggctt tggggtaatc cttttcaaag tccaagatat tctgcatatc
    19141 agcaccacgc caaccgtaga tagactggtc cgcatcccca accacacaga tatttttaaa
    19201 acgggaagcc aagagtttga ccaattggta ctgagcgtgg ttggtatctt ggtactcatc
    19261 aacgtggatg tattggaatt tttgctggta gtaggttaaa acatcaggat tttgatcaaa
    19321 gagacgcaag gtcagcataa tcaaatcatc aaagtcaacg gattcagact gacgaagttc
    19381 tttttgatag gctgtataac actgggccac aatttgcgta tacatatcgc cagcttgggc
    19441 agcataagca acatcatcaa tcaaatcatt cttagcattg gaaatggtcc ccaaaatagt
    19501 tcgttcattc cattttttag gatccaagtt caactgtttg agaatacgtt tcatgagcgt
    19561 tcgctgttca ccaggatcca caattgtaaa attacgattg tagccaatat ggtccgcatc
    19621 gcgacgcaaa atacgcacac acatggagtg gaaggtcgca atcagacagt cctgagtagc
    19681 tggattgagg ctataagcac gctctttcat ctcacgcgca gccttgttgg taaaggtaat
    19741 ggccaagata ttccaaggat tgaccagctt ttcatcaatc aaataagcga tacggtgggt
    19801 taaaacacga gtctttccag aaccagcccc tgccatgatt agcaagggac cttctgtcgt
    19861 ttgcaccgcc tcagcctgac ggtcattcat tccatttaat aatgcgttca tcttctcttc
    19921 cttactcttg aagtcaatat ttctattata tcagaaatca gggaaaatag aaactttacg
    19981 gggagtagca aaatatagtg gattgaaact agaatactac actgtgggtt tctaaaacac
    20041 tcgacttttc acccaatttt ttcataaact agctcaatac ctcaatagac ttcctgcaaa
    20101 actagaatcc tagttcatga ttgataatac cagcaatcaa attcattcgt aatccgaagc
    20161 gtttacgatg atttcgatag gttgttgaaa acattttaaa cgtttctact ttggcaaaga
    20221 tgttctcaac cttgcttctc tccttagata gcgcatggtt ataggtttta tcttcaactg
    20281 ttagcggctt gaatttgctg gatttacgtg gagtttgtgc ttgaggatat atcttcatga
    20341 gcccttgata accactgtca gccaagattt taccagcttg tccgatattt ctgcgactca
    20401 ttttgaacaa cttcatatca tgacaatagt tcacagtgat atccaaagaa acaatctccc
    20461 ttgacttgtg acaatcgctt gagccttcat agcgtagcat ttctttttac cagaatcatt
    20521 cgctaattgt ttttttaggg cgattgattt ttacttccgt cgcatcaata atcattaccg
    20581 tgtcctcaga gctgagagga gttcttgaaa tcgtaacacc actttgaaca agagttactt
    20641 caacccattg gctccgacgg attaagttgc tttcgtggat accaaaatca gtcgcaattt
    20701 cttcataagt tcgatattct cgcacatatt gaagagtggc cataagaagg tcttctaggc
    20761 ttaatttagg ttttcgtcca ccttttgcgt gtttaagttg ataagctgtt tttaatacag
    20821 ctaacatctc ttcaaaagtg gtacgctgaa cacaaacaag acgcttaaat cctgcatcag
    20881 ttagttgttt acttgcttca tcattcatag aactactata ccatatttta tttcgcagga
    20941 agtctaatct aaaaaaggta aatttaagat tggcaatacg aacgttaaac agaattccat
    21001 ttctcttttt agaatcaaaa cgacaatatt gtggaatctc tacaggaaca atagactgcg
    21061 acactaaaat atcctccctt agttttactt tactaatagt atataggagg agagccctga
    21121 atcctagacc ctttgttatg atgcgcttac aaacagagtt ggaaaaaatc ttaaaagcag
    21181 aaaaacgcat gatatcagcc cctaacactt gatacaatgc gttttattat gaaaagatct
    21241 actggatttt ttatcaaaat aaacttccag tagtcttttc actttttatt aataagttcc
    21301 ttcttcacct tggctagtca agataacagg tccatctttc gtaatgacaa attggtgttc
    21361 atactgacat gacaatccac cgtcaatggt cttatgcgcc caaccagttt tcatatctgt
    21421 atcaatttcc caatcgcctg tattgatcat tggttcaatg gttaagacca ttccttcacg
    21481 aagacggagt ccacgacctg caataccata gttaggaacc attggttctt cgtgcatagt
    21541 tgggccaaca ccatgaccaa ccaaatcacg cactacaccg taaccacgac tttcagcgta
    21601 ttcttgaata gccgcaccga tatcaccgat acgatttcca acaacagctt gctcaatacc
    21661 cttgtacata gcttctttgg ttacatccat caagtttttg acttcttcgg acggtgtacc
    21721 aacagcataa gcccaacatg agtctgctaa accaccagaa tagctctgag tgtatttttt
    21781 catttgttca acattgttga agtttaattt tgagacattt aggtcagatt tagcaatggg
    21841 acctcccaaa accatatcaa ctttgagcaa atcaccatct ttcaagatat aatgacgagg
    21901 gaaagcgtga gccacttcat cgttaagaga gcaacaggta gcataaggat agtccatcat
    21961 ggcaccgtca accccaatct gaagtggaag gaaattttct tctttacaac gacggcggac
    22021 atattcttca acttcccaca tatctacgcc tggcttaatc aaatcacgta agcctatatg
    22081 aatacttgct agaaaatcac cagccttgtc catagcttcg atttcacgag ctgattttaa
    22141 tgttatcatc ttttctccta gtttctaatt aattttaaca gtcacatttg cttttgaaac
    22201 aatctggtga ccatgataaa tatcgtaatc aattatagct gaccgtctcg tatgatgaat
    22261 aatccgtgcc tgaatgcgca atatatcatc tatctgaaca gcctgcaaaa agtagatcag
    22321 catctgctcg ataatgagat tgcgaccact attaacaact aaatcttggg tcatgtgggt
    22381 cagaatttct gccaatacac cattagccaa aactccattt ttttctagca taaagggttc
    22441 cactgtaatg actacttcat catggtgata agagagcttt tgtccaatct gctcagaaaa
    22501 agttggtaga gccgaaactt gggaacggct catcttctcc atgacatctc gtcgcgtcac
    22561 aacgccaagc aaagtttgat tgcttcgaac aactggtacc atttcaaagt cttctgcgat
    22621 catccgttga ctcacattgg caatatttgt cgataatcca acccaaaata gactacgaga
    22681 cataacctta tcaattgtcg tgcttggtga tttatcacca gcgtctctca tggttacaac
    22741 accaacaacg acctgatgtt gattgataac agggaaacgg ctgctacgat tcttacgaac
    22801 caagtccaaa taatctttaa ctgtatctgt ctctctcaga aaaccatact catgactagg
    22861 gcgataaagt ttctcaactg tcagaatatc agtcttgatt tggacatttg acaaggcttt
    22921 attgatcatg gtcgcgacgg taaaggtatc atgcttactt cttagaacag gaatcccttt
    22981 ttgattggcc agtttaagca catcatcatg aacctgaaat ccccctgtaa ccagaactgc
    23041 attttcattt tccaaggcta gcaactgaat acgggttcgg tctccgacaa tcaagagccc
    23101 cccatcatga aggtaagaca agatattttg ttcagtcatg gcaccaattg aaaacttact
    23161 aaactctctc tctaaacctt cttgcccagc cagaacctca gaagaagtca cttctgcaat
    23221 ttcagcaaac gttaatctct ctatagcaac tttctgggat ttaacacgaa ttgttccact
    23281 tctaggacgg gtctccacaa ttccacggtt ttcagcttct ttaatagctc gataggctgt
    23341 tccatcacta actcctagat gattcgaaat gctacgaaca ctgacccttt tacctactgg
    23401 taattcctcc aaatagctta gaatttcctg atgcttactc attgaactct ccttttacat
    23461 accgaaattc aagataatcc cgcatttttc ttgtgtaacg atcacttccc ttaaactgac
    23521 ggaacaaact aaatccagac ttaagagcaa ctctttggct agcttcattt tcaaggtggg
    23581 taatgataaa taattgtttt aagccaaatt cctcaaaaga aagctgacaa atttttctaa
    23641 caacctctgt cataaatcct tgcgaccaag catcttttct caaaaaatag ccaagctcag
    23701 cttctttttt gatttcatct aacttctcaa atttaataga accaatcatt tgttgatttt
    23761 tctggtcaca aattgcccac actcccaaag gggacttcat aaagtaattg gccagtgcat
    23821 attgactttc ttccagactt gcctgcgttg ggaaaataaa ttgaagattt tctggatttg
    23881 aagctatctc gcggaagtcc tgactatcac taaaaaagaa aggacgcaaa tacaagcgat
    23941 ccgtttcaaa aaaagaaaac attgctaatt tggtccaaat attcataaac acctctacgg
    24001 tttaatcctc aacaagtcta atatccgctc ctaaattacg taatttttcg ataatatcag
    24061 aataaccacg taagataaac tcgatattgg taatttcagt tttaccttca gccataagcc
    24121 cagcaatgac tagtgcagcc ccagctctta agtcggtcgc tttaacactg gccccacgta
    24181 aatcacgtcc acccgtgtac aaaatatgac catttgttgt cgaaatatcc gcatccatct
    24241 ttgctagttc aaaaacatga tttacacgtt tttcgtaaat cgtatcgaca attgtaccac
    24301 gaccattcgc tcttagtaaa agaggggtaa gcggttgttg caaatcagtt gcaaagcctg
    24361 ggtaaggagc tgtcttaata ttgattgctt tcaaattaga ctgttcctcg acaaaaatgc
    24421 tgtcttcaga tacagtcatt ctcactccca tttcttccaa cttagcaata aacccttcca
    24481 ggtgttcgta aagaacatta tttatacgaa ttcctttacc aactgcagca gctaaagata
    24541 tatatgttcc agcttcaatg cggtctggaa tcacctgatg acgtgtccca tgtaatcttt
    24601 caacaccatc aataatgatg atattagttc ctgccccacg gatatgggca cccatattat
    24661 tcaagagagt agctacatca ataatctcag gttcacgggc tgcattttca ataatagtac
    24721 gaccatttgc tttaaccgca gcaatcatcg tattaatcgt tgctcccaca ctaaccgtat
    24781 ccatgtaaat acttgcacca tgaagtcctg tatctttagc agataacttc atgttatctc
    24841 cctcgtagct agcagtggca cccatagctt caaacgcctt aaggtgtaag tcaatcggac
    24901 gaggaccaag atcacatcct cccggtagac caactgtcgc ttcaccaaaa cggcctaaga
    24961 ggctcccata aaaatagtaa gatgcacgaa gactgttaat tttaccataa ggcattggaa
    25021 tattttgaac acctcttgga tcaatctcca agacatcgtc ataacgctta acagtagctc
    25081 ccattaattc catgatttcg acaagactgg ctacatccga aatatctgga acacaatcca
    25141 aagtcaccac atcatcagcc aatataatag ctggaattaa ggccacaaca ctatttttag
    25201 caccactaat agtaatttca ccttgcagtg gtaatccacc attgataaca atttttctca
    25261 ttctaagttt tcaatactct ttcaagattt ctaataaggt cttcaaaata aagtatatca
    25321 taaatttatc cttttttcca tccttttcaa ttttattgga taaatcagag ttgacgagtt
    25381 agtaactgaa ttactaatac tcaataaaaa tcaaagatca aactaggaaa ctagccgcag
    25441 gttgctcaaa acactgtttt gagattgtag atggaactga cgtagttagt atcctacaca
    25501 tacggcaagg cgatattgac gtgatttgaa gagattttcg aagagtataa tctttctcga
    25561 atcgctattg cccctttttt atcccctgaa actgagtagg agctaagact agatctctta
    25621 tctaagtatc ggaatacggc tgttcaacta aattttagca agaacttctc ccccttctct
    25681 cagttcacag aagcgtttta tacataccgt cctatatttc atgaacaaga cgttttcagg
    25741 ctagcatcct atcagacaat ctattttaaa gataaccgtg actcaggatc acttctatct
    25801 gtcgttttct ctttatagtg atagacctca cgggataagt cgtacatctt tcctcgtgta
    25861 tacaagatat gaggacgtta aaaggttaca gtaaaaatag aaaatcttag tacgaattca
    25921 attactctca tgatttacgc atataggtta cgactacctt tttggacttt agagtttgag
    25981 gccctcttat tcgctatata cgccttatta tcacgttcct gttcgtagag ccacgatttc
    26041 gctatccctt cttctgacaa ttcttatttc cagcatcaga cttaaaacgg tctatcccca
    26101 gaccatttta atccgctacc tcacgatagt caggcttggg aatcactatt tgactcgccg
    26161 agaactttga catcagatat actataacaa attgaaataa gaataaaaca atttaatttt
    26221 gaaattcaaa tcaatttata gcaatatttt agaagatatg ctgtgctatt ccagattcag
    26281 tttgctatac atgcctgtcg taccacaaaa tcccgtgtct gatgaggcac gggatttttt
    26341 agcttcttta ctgagatgga ttttcctttt tagttcgtgc caatctcaag gcacgatttg
    26401 gattgagacg attaaatagt tcttccaatt tcttttcatt ccaaacgtct gcggcggaaa
    26461 caaaattacc atccgcatct cggaaagata tcggtttatc tcccatacca gtctcctagt
    26521 ctacaaattc aaactcaaat ttaccaatgc ggaccaaatc cccatcttta gctccacgcg
    26581 cacgaagggc ttcatcaacc cccataccac gaagctgacg ggcaaatttc atgacagatt
    26641 catcacgatc aaagttggtc atattaaaga gtttcatgag tttttcacca gaaagtaccc
    26701 atgtcgcatc gtcatcacga ctaatttcaa aggctttttc ttcttcgtca aatccatagt
    26761 aagcttcttc ttccatatcg gactcgtcgt agagcaaaaa ttctggtgtc ttgtctaaca
    26821 attcagctgt agcatctaaa agtgttgcca gaccttgctt ggtcaatcca gaaattggga
    26881 agatagctgg taactcttca aattcatcat aattttcaga caattttttc ttaaattctt
    26941 caagattttc ctgactctca ggcatgtcca tcttattagc tacaataatc tgtggacgct
    27001 ccatgaggcg aagattgtaa gactccagct ctttattgat agctaggtaa tcctcatatg
    27061 gatcacggcc ttcgctagct gacatatcaa tgatgtgaag gataacacgt gtacgctcga
    27121 tgtgacggag gaactgagtt cccaaaccaa caccttgact agccccttca atcaaacctg
    27181 gcaagtcggc tactgcaaag gattcacctg attgggtgcg aaccatacct aaatttggta
    27241 caatagtggt aaagtggtag gcaccaattt taggcttagc tgaggtaata acacttaaaa
    27301 gtgttgactt ccctacagat gggaatccta ctaaaccgac atctgccaag atttttagtt
    27361 ccaattgtaa ctcacgttcc tgacctggtt ctccattttc agagatttcc ggtgcaggat
    27421 tttttggtgt cgcgaaacga atatttccac gtccaccacg accaccgtgg gcaacgataa
    27481 attcttgccc atgttcaatc aaatctgtta aaaccttgcc agtctccgca tcacgaacag
    27541 tcgtaccttg tggtactcga actctaaggt cctcagcacc acgaccatgc atccctttgg
    27601 tcatcccttt ttcaccagaa tcagccttga aatgacgatt gtagcggaaa tccatcaagg
    27661 tacgtagtcc ttcgtctaca acgaagacca cattgcctcc acgaccacca tcaccacccc
    27721 aagggcctcc attagggaca tatttttcac gacgaaaggc aaccatacca tcgccaccat
    27781 taccagcctt gaccttaatc ttagctgtat ctaaaaacat actcattatt tcttctcact
    27841 ttaaaaaagg gctgggaaat cccagtcact aaattttctt gaatctattt tatagattac
    27901 tgagggcacc aattgcagtt gcaaaaattc ccaataaact tgctactagc atgataatca
    27961 cgataaacaa ggttattttc tcaaacatag tttttttacg atttccatta tctccaaatg
    28021 ccatttttct ctccttcgtt acattctatt ttctattatc ttagcatgaa ttgagctagt
    28081 tttcaatagt cagttgctac tggtgcgata atccataaaa taatgtaagc tacaattcca
    28141 gctccgtaac agcaagtaag aacaccccaa atgacttgaa cgatagtcgg atccatatcc
    28201 agataatggg ccaccccagc acaaacaccc gcaatctttt tatcacgacc gcttctcatt
    28261 aattgttttt ttcatagctg ttcctctttc tattcttcat ggtctttcca atagtctctc
    28321 atactgatca actgtgtttt tgaagccttc aacatgcgtc tagatccttt tacaggtaca
    28381 gcaaccacct gttgctgaag atacaaaact gtcttaaaga tacgctgact gaccgtatca
    28441 tctttagcca aatctttctg gaagttattt gaaataatgg catccagata aaactcatgc
    28501 actcgtttcc caaagttctc agctgaaatc tcatacaatt tctctgataa ggtatgctcg
    28561 ttcatgtctg gtgttgcaat cagggcttcc aaaatagcac cagccaaatc atgttctcca
    28621 tagtacaagg ttccaaacat tttatcactg atgaggttgt tcaaataagg atttccgtga
    28681 gcaatgacag gtgttccact ggctaagctt tccaagtagg tcaaaccttg cgtttcgctt
    28741 gtcgatgccg aaatgaagaa atccgccgct ttatagtaaa gagccgtctc actaggagca
    28801 atcatccctg taaagatgac tgagtcttga atctctaggt tctgagcttg ctctttgagg
    28861 tcattcagat aagggccatc cccagctact accagtttaa ccttgtcttc ctctttcaga
    28921 acatcagcaa aggctgctaa aactgcttga atattttttt cataggagat tctcgaaaga
    28981 ctaagcaacg tcttttcacc atcttgaatc cctagtttac tacgcagttc tttcaaattt
    29041 tcctgcttga tttccggacg ctcaaacttg gctaattcaa tcccagtagg aatgacccgt
    29101 ttttcaacct tgaccttata atcagatagc aagtcacgga caatctcact aggacaaata
    29161 accccatcca catcatgcag gaaacctcta accagatact tgaccatact cggccggatc
    29221 aacatcccct tagcaatata atggacatag tcttcatact gggtgtgata ggtatggatg
    29281 actggaattt tcaattcacg cgcaatccaa atccccaaca ggccaagaga aaattctgtc
    29341 tgagtatgga taatatctag ctgatactgt ttagcaattt caagtgcctt gctaaaacct
    29401 cggtaggcaa agcgacgatc cttaaaagca aagaaaggaa cacttggaat gcggataatt
    29461 tgccaatctt cgtagcgatt gacatcctta tctgtcgtcg taaagataaa aacagcatgt
    29521 ccctgctttt caagttctgt tttcaaggtt cgaatactgg tcgcaacacc agaaacctga
    29581 ggaaaatagg tatctgtaaa taaaccaatt cgcatagatt acctcacttt ttactttctc
    29641 cctaaagcgg cttgtttctc ataaaagtcc aaccagattt gtaacagatg ctcttcagaa
    29701 tactctctgg aaatattctt agccttttct ttgagatctt ttaaggcagc aggatttgct
    29761 tgatattcca aaatagcctc tttcatctct tctctacccg ctgtcgcccg ataatttccc
    29821 tccaaaatta ccttatagag atctaaatca cgcaacataa taggagcctc acaactcgca
    29881 gcttctaaaa tagtcatagg aaagagctca ttgtaactag gcaacaagaa aagatccgct
    29941 agagcataca attcgcgcat ccgctctggc gatacaatgc ctggaaaaat caaattttta
    30001 gggggatttt ccataatttt cttatagtgt tcataaccat ctgtcatacc accaaaagag
    30061 aagccaccag cccagataaa ggtaatctga ggcaattcct cagccagacg gataaagtca
    30121 tcaatccctt tacgtttctg aacttgccca gcacctacta cgataaactg attgtcacta
    30181 agaccaagat ctgtgcgcag tctgactacc tcttcttgtg gtagaggatg ccatttttcc
    30241 ttgttgacaa agttaggaat ataggtcact ttttcacgtg gaataccagc tgctaccaaa
    30301 tcctcaataa acataggatt gaccacaacc aagtgctcca tccggttgta aaaagaaaat
    30361 acatagcgtt tcacaattcc ctttaagaaa aatggaattt tcaaacttcc ctcaagtgta
    30421 gctggcaaga aatgcacata gccaatcttt ctccctgagc gtttcttttg gaaggttgat
    30481 aaataatagg gaaaatcaat cgtatgaaag tgagtcacat ctgcctcgat tggaagattt
    30541 tctgtaacaa tcaattggtc cttggcagca cggtgaagaa gacgaactaa ttcacggtaa
    30601 gcacctgaaa ctccctgtcc tgctactttc tcacttgaac tcaacatatt gatgcgtaat
    30661 ttctttttct ccataactac tattatatca ttttctttga ataaaatcag caaaagaaag
    30721 gagagactag aggaaaagag gggaaatttc ctcgcttttc caacagtctc tcacatgctt
    30781 ttatatgttt acttaatgcc tagggcaatg cgggcatagc gactcatttt ttcaactgtc
    30841 caggctggat accagactaa tttaacctca gtatccgtta cttctggaac ctctatcata
    30901 gcatcataaa tctggtctgt caaaaggtct gctaagggac aacccatagt tgtcaaagtc
    30961 atgtcaatct ctgtttgccc tgtgtcaccg tcaaaacgaa tctcatagat caaaccaaga
    31021 ttgacaatat cgattcccaa ctcagggtcg atgacttctt ccaaggctgt taaaatccgt
    31081 gttttgatgt tttcaatttg ctcttctgta taagccatat tttcctcact cttagtcttc
    31141 aataaaatca cgaagcggtt tgctacgact tggttggcgt agttttctca aagcctttgc
    31201 ttcaatctga cggatacgct cacgagttac gttaaagact ttccccacat cttcaagtgt
    31261 gcgcattttt ccatcatcta gtccaaaacg tagacgcaga acattttctt cacggtctgt
    31321 aagagtatct aagatttcat ccaattgctc acgcaagacg atacgagtcg tataatccac
    31381 tggattttca atcacttcat cttcgataaa gtctccaagg tggctatcgt cctcttcacc
    31441 gataggagtt tcaagagata ctggttcttg ggcaatcttc aagatttcac gaaccttatc
    31501 aggtgtcata tccattcgtt cagcaatctg ttctggtgtc ggatcttgcc ccaattcttg
    31561 aaggagattc cgctgttcac gaaccaattt attgatagtt tcaaccatgt gaactgggat
    31621 acggatggta cgagcttggt ccgcaatagc acgagtgata gcctgacgaa tccaccaagt
    31681 tgcataagtt gaaaacttga accctttaga atagtcaaac ttgtcaaccg ccttcatcaa
    31741 gcccatattt ccttcttgaa tcaagtcaag gaactgcatg ccacgaccga catagcgttt
    31801 ggcaatggaa acaaccaaac gaagattggc ttccgcaaga cgttgtttgg cttcgatatc
    31861 accagcttca acagccagtg ccaactcttt ctcctcttca ttggtcaaga gaggaacgac
    31921 ccctatttct ttcaagtaca tacggacagg gtcattgacc ttagcagaag ttgacccaat
    31981 caagtcctca tcgctgagtt ctggttcttc ttcattgcta agaacacgcg cacttggatt
    32041 tccttcgtta tctgtgatag aaattcctgc atcctgaatc cgttgcaaga gatcttcaat
    32101 cccatcagcg tccaaggtaa aaggaataac cagacttgca ttgatttcat catctgttgc
    32161 tgtccctttt tgcttatgat tacggataaa ttctgctacc tgtacgtcaa atgttgttac
    32221 ttctttttgt tttgttgcca ttattactcc attcttctct tttgggaaat taaacgttcc
    32281 aattcttcta gggctgtatc tgtatctcct acatggctag cttcctgcac cttctttttg
    32341 attctcatat tgtcctgatt caagagagcc ttgtttcgag tcatctctac ttcactaagt
    32401 tcctgcggcg atatttcagc aggcaaatcc tgagctaaaa cttggtacca agctctttca
    32461 acttcctctg tctgctctgc taaaacttct ggaggaagat ttccatactg gccaagcaag
    32521 tcatataaga cctgaaattc aggtgtagca aatgcaaagt cttctcgcaa acggtaatcg
    32581 ttcaaaacaa gaggggattc catcatccga tagagtagat gggcttctgc cctcataata
    32641 gccgataact gcttggtgat tggcatggtg attggcgtcg gtctggaaat tccttccatg
    32701 cgattctgcc tttgcacctg acgactctca ttaacaatct gctcaatctg ggtataatca
    32761 aaggacgcca gactgtcagc taaaatatga atatagctgt tttgagcagc gatggacttt
    32821 tcttgaacaa tcaagggagc tattttttca agaaactcaa tctgagcctg cagattttca
    32881 ctgttttcag gtttgtactg atgaatgtag aactcaatcg gactaatacg agttttcgtt
    32941 aatagatagg ccaagtcttc tggaccattt ttttgtagat actcatcagg atccaagtta
    33001 tcaggcatgc tgacgatttg cacaggcata tcaccaattt catccaatgc tttcaatgtc
    33061 gcggcttgcc cagccttatc tccatcgtaa acaagaacca atttcttggt taaccttttc
    33121 agatgctcaa catgctctcg actcaaggcc gttcccatcg acgccacagc actttcgatt
    33181 ccagcccgat aggctgcaat aacatccatg aatccttcca tcaagtaaat ctcactagct
    33241 tttccagaag atttttttgc cctatccata tgatataatt cgtaactttt gttaaaaatt
    33301 gcagtcgatc ggctgttttt atacttagaa gtttgtgaat ccgttttttg ccagatacga
    33361 cctgagaagg caatgacctt tccttggtca tttgtcaggg gaaacataat gcgattgtga
    33421 aaggtgtcta caaattgatt ggcatccgag agataaaaca ggcctgaatc cagtaaatcc
    33481 tcttcacgat actgatcaga caaacgttga tagagatagt ttcgttctgg aggtgctaaa
    33541 ccaatccaaa aatgtttaag cacttcatct gtcaaacccc gctgataaag gtaatttctg
    33601 gcctcttcgc ccatagtcgt tgtcatgaga atcgcatggt aaaatttggc tgcatcttcg
    33661 tgcatatcat aaagagcttg gtgaggtgag gctggcttct gctcactata aagcggtttt
    33721 tcaacctcaa ttccaacacg ctgacctaag atttggactg cctctataaa gggaacccct
    33781 tggtactcct cgatgaactt aaagacatca cctgagcgac cacaaccgaa acagtgataa
    33841 aactgcttat cctctacaac gttgaaagaa ggtgtttttt caccatgaaa aggacagagc
    33901 cctagatagt tccgtcctgc cttttgtaaa gaaatcacat ctcctatgac ttccacaatg
    33961 ttggcattgt ttttgatttc ttcaatgact tgtttgtcaa ccatacacaa tacctccatg
    34021 ttatcatagt ttactttata tagtatactt tatttcagaa aaaaagtaaa ccatttcact
    34081 cattttccct actttattca aagagttgat aataatcaga gattttcatt tttgcttttt
    34141 cttcttggtt taaatcttgg ataatccgtc cttctttcat gacaatcaag cgattgccgt
    34201 atttgagagc atcttccata tgatgagtaa tcataagggc tgttagctga tctttcttaa
    34261 caaattcatc tgtcaattcc atcaaagcaa cactagtctt tggatccagg gcagcagtat
    34321 gctcatctaa caggagtaat tcaggtcgct tcaaggttgc catcaagaga ctcaaagcct
    34381 gtctttgtcc acctgataag aactcaatcg gtgtattcaa gtgtttctca agaccatttc
    34441 ctactttttc aatggttgcc tgaaattcat ccttatagct agtcaagcgt cgtggtaaca
    34501 atccacgctt ttcaccacga aacttggcga ttaaaagatt ttcagcgacc gtcatacggg
    34561 gagctgtccc catctttgga tcttggaaga cacgagacag gtacttggca cgcttctcgg
    34621 gtgaaaactt agtgagttct tcacctaaaa tacggatagt tccactagtt agtgataagg
    34681 tccctgctat agtgttaaag agggttgatt ttccagcacc atttccgccc aaaatcgtga
    34741 taaagtcccg ttcaaaaatt tctaaggaaa catcatttaa aataatcttt tcttcatcaa
    34801 agccattttt aacgattttg gttgcatttt ttaattctac aattgctgtc atttgcttaa
    34861 cttggctcct ttcaagattg tttgcttaaa tgttggaatc atgaggcaga ctgctaaaat
    34921 caaggcactg tataaacgaa ggtaacttgt attaaagcca agtgcgataa ctgcccacac
    34981 taaaaattga taagcgatag aacctacaac gatagtaacc aaacgctctg ccaagctcaa
    35041 actcttgaaa ataacttctc caataatcaa acttgcaagc cccacaacga taaccccgat
    35101 ccctcgagac acatcggcat aaccttcttg ctgagcaatg agggcacctg caagggcaat
    35161 cacaccattt gataagacca agcccatgag ctccatgcgt ccagtatgaa tcccgaaact
    35221 tctagccata tcaggattat cccctgtagc aatataggct tgtccgagtt tagtgtccaa
    35281 gaaaaagagc atgagagcaa taacaatact cacaaagatg agacctgtca agagttgatt
    35341 caaatccgaa tcaaaaggca aaacatcctg aatttgcttg gttccaagca ggcctaaatt
    35401 cgcacgtccc ataatcaaga gcatgattga gtgacaagaa gtcatcacca aaatccctga
    35461 gagcaaggtt aggatcttcc cttttgtata aagaaggcct gctgccattc cagccaaaca
    35521 acctgctcct acagcaacaa gtgtcgctaa aaatgggttc acgcctttgg ttatcaaagt
    35581 gacagcaaca gctcccccaa gagggaagga accttctgtc gtcatatctg gaaagtttaa
    35641 aatcctaaat gtcataaaga ttcccagacc tagaatagcc cagacaaatc cttgagaaat
    35701 aatggaaaca atcatatttt atttaatcct ttctatattc atctttttaa aaaatgggaa
    35761 gagtctcctc ctccctacct tatttattcg atgacttgtc ctgcttcttt gagaacagac
    35821 tcaggaatag taatacctag ttcttgtgct atttttttat tgatgactga cttaccagtt
    35881 gaaaagacat tgactggggt atcggctggt tttgcacctt tcaagacttg cacaatcatt
    35941 ttacctgttg ccacaccaag gtcatgttgg tcaattacaa ctgatgccaa accacctact
    36001 tctaccatag ctgtcgcact gggataaatt ggtttcttag aactttgatt gctagagaca
    36061 accgttggaa atcctgatgc aatggtgtta tcaattggaa cccaaatagc atctaccttg
    36121 ctagtcataa cagtgacagt tgaggcaatt tcatttgttg aaggaactgc aaatgtttcc
    36181 actgtcagac ctgctttttc agcataagcc ttaaattctt cgacctgtgt ttttgaattg
    36241 tcttcgctac ttgagtaaag agctccgatt gttttcacat tcggtgtcag agccttgatg
    36301 agttcaactt gttgttgagc tggattgtgg tcagataccc ctgtaatgtt gccacctggt
    36361 tttttcaaat ctttaaccaa gttagcacca attgggtctg taatagcggc catgataacc
    36421 ggtaggtctt ttgttgcact agccaaccct tgggctgctg gtgttgcgat accaaccaca
    36481 aggtcattcc catttgcaac caattgttta ctcattgtcg caaccttact ttggtcacct
    36541 tctgagttca taaaatcaat tttaacttga tcatctttat atccttcttc tgcaagtcca
    36601 tcttggatcc ctttataaat caaatcaagg gatggatggc tcacaaattg aagcacacca
    36661 atcttagtta ttttcttctc atccttatta ttctgagctt ctgatttatt cattgaagaa
    36721 taaatcaagc ttcctgctac taagactgct aatgcagcaa taattccaat taaacgttta
    36781 tttttcattc tgtttctcct ttttatttcc tttaacatat ttcacttatc taaacaagcg
    36841 acgccatcgt tttctttcca tactaacctc catcaaaaaa atcctcacac aaaaaacttg
    36901 tgtgaggacg tcgatgcgcg gtaccacctc aattataggg aatttcccta tcgctcagtc
    36961 tcgcaataac gagatgcact gtaaggtgtg cttaccgaat ttttataatt tcaaattcta
    37021 aatagcattc agcccaattt tcatcatcgc cacttatctg ttttcagcta ccacagactc
    37081 tctaaaaagt ttgtatgatt acttttctga atggttaaat tatatcattt ttaaactact
    37141 tgtcaatagt ctattagaat ttttttgata ttcactttta gcattcactc ttgaaaatta
    37201 tcaacctgaa ttacgcaatc ctgtcgcaat tccgttgatg gtgatatgaa tcaatcgttc
    37261 ttgatcactg gacaattctc cacgacgttg gcgtttaatc aactctaact gaatatagtt
    37321 gagaatatta aagtaaggca tacggtaatc cagactagct tttagatatg gattgtcagc
    37381 taagagttcg tcatgtcctt caatagccaa gataacgttc ttagtaactt gccattcatt
    37441 taaaatagtc tcatagatgg ccttaacttg ctcgtcttca caaagtttag catattcaaa
    37501 agcaatattc atatttgatt ttgacaaaac catatcaaca tttgaaagaa gcgattggaa
    37561 gaaaggccaa ttttggtaca tatctcgtaa gatagcaata ttctctggat ttttattgat
    37621 aaattccttg aagcttgaac caaccccgta ccatccaggg aacataacac gactctgtga
    37681 ccatgagaat acccaaggga tggcacgcaa accaccgatt tcagtaatag tcttacgagc
    37741 ggctggacga gaaccaatat taaaacttga aatagccttg attggacttg actcgaagaa
    37801 ataatcatag aaatgctcat taccaaagac caaatcacgg tagatatcgt aactacggtc
    37861 cactacttga tccataatgg cttcataacg atttggggta ttggtatcgc tcttcttctg
    37921 agtaatcata cggttaatag ctgccgatac tagcatttca aggttatagt aagcggcgtc
    37981 tttgttaccg tatttattcc caattacttc accctgctcc gtcaagcgga tacgatcctt
    38041 gatagacttg agcggttgag atgtaatggc ttcataggtt ggcccaccac cacgaccgac
    38101 agtaccacca cgaccatgga agaaggtaac cttaacgcca aattcatctc caatagcagt
    38161 caattgttgt tgagccttgt agagggtcca acatgatgac aagtaaccgc catctttatt
    38221 actgtcagag tagccaagca tgatttcttg gtagttattt cgtgagtcaa tccatttttt
    38281 ggcaaggcta agagaaagat attttctcat tgtttcttct gaatgatcca agtcttcaat
    38341 tgtttcaaaa aggggaacaa tctgaacacg cgccctttcc gtatccacca gtcctacttc
    38401 ttttaacaga atagctaatt ctagcatatc agaaaggctg gttgcatgtg aaatgatggt
    38461 ctgacggatg acatcatctc ccaacttatc tttcaaaaca cgagccgtct taaaaatagc
    38521 taattctttt gctaataatt ctgatttttc tgcgtgagtc gcagaaagaa ttcggggatc
    38581 ttcttctaat tctttcaaga gaaggtcaca cttttcttct tcgctcaact cgctataacg
    38641 agaatgaatt cctgctgatt tcaagagttc tgccacacag gcttcataga cgctagagtc
    38701 ttgtcgcata tcaattgatg ctaggtaaaa accaaatatc tctactgcct gcaataattc
    38761 cacaaaatca cctgaaatca aggactcacc cttattttct agtagagaat ctcgaatggc
    38821 aatcaaatcc ttgtagaaat cattggcggt ttcataacga gtcccaactt cttcatcctc
    38881 aatcagatag gttttagttg cctgaatttt tgattgaata tcaaacaagg cacgacggta
    38941 aagctctttt tcgcggtaaa tcgagttatc cttggattga cgagccattt ctctgacttg
    39001 cttgctgacg ttgacaatgc tagttgaaag agaaaattca cgataaagtt ggtaaatctt
    39061 tttatcatag tagttcatga tgacttcaca ttgagtgagt gcagactgct tcaaggtctc
    39121 tgctgtaaca aatggatttc catcacggtc accacctatc cacataccca tggtgattgg
    39181 tttagcctgt tttaaattca gaccatgcgc ttgcgctaag cgcttatact ccgtcgtcaa
    39241 atgaggtaca gctttcaaaa aggagctgtt ataatattcc atagcattcg tgatttcgtt
    39301 agtcactttt aattttttct cacgaatcat gtctgtctgc atgataattt cgatgtaacg
    39361 acgcaaatca ttgtaccatt tatctttatt gatcaacccc aacttaacat cacggtattt
    39421 acgcaaaaga ctatgaatat gatttgttaa atccaacata cttttgcgtt gcacttgtgt
    39481 tggatgggct gtcaaaacag ggacaacatt caagtgttct aggatctcaa cggcattttc
    39541 cttttctgct accaatttaa tcgttgtaga taatttacct aaatagtcct gatcaatatt
    39601 attttgatga ttgatttcat aagctaaatc cacatcctct gaaatattga tcaaaagagg
    39661 taagatagag aaatagcgtg aaatatagac catttcatca tttgataagc tagtcactag
    39721 acggtttaga ccttgataat cttcctgcgt tgataattct ttcaactgta ttattttttc
    39781 aaaggtctct ggggcaagca tatttttagt aatatcttcc agtaattctg ttagaatcaa
    39841 gacttcttct tgcacaacac ttttattact ataattttct aatttttgaa gagacataaa
    39901 ctatcctttc tttatcctac ttcaacagaa ggttcattgg ttgattttcc aattctcggt
    39961 acaacttagc gcgtttttca ctggcatcaa tatttaagac aaaggctact gccactgata
    40021 agactagaag actatttcca ccctgggata agaaggggaa ggttactcct gtagatggaa
    40081 tcaagcccga aatccctccg atattgacaa atacctgaac caacatcatc cctccgacac
    40141 cgagtgcaac catggcattg aaaggattct ccgctcgaat accgaccaag ataatccgca
    40201 aaatcatgaa aaacaagaga gctaaaataa gactggcacc agcaaagcca aattcttcaa
    40261 tcacgataga aaagacaaag tctgtatgag cttctggcaa ataacctcgt ttttcaatcg
    40321 agtttccaag acctagacca aaccaaccac cattgaccat ggcaaaataa gaattagcta
    40381 actggtgacc tgcatcagca cgatcggcaa aaggattaaa aaaggcacta aagcgcttgg
    40441 ctacatagcc aaatactgga atttttgaaa aggtctcaac accgattagg ctgatagtgg
    40501 tcaagacaaa gacagaagcg gcagatacga gcgccagaat ggttgaaaac cagcgataag
    40561 cgattccact aactgtatac ataatcaagg aaaccaagac taaaatagtc gcatttccta
    40621 aatcagggaa aattcccaaa cttccaatca gaactaggag aacgaatcgc caatcattaa
    40681 aagcacgggg aagccattga ttttgagtca aaacttgaaa atcataagta gctatttctt
    40741 cttgctgttt ggagaatcgg tgagctaaat accaaataat aatgattttt aagtactcag
    40801 ctggctgaat agttactcct gcaaccgaaa tccaaccgta tgccccgttt acggaaatac
    40861 caataaaacg agccaagaac aataaaagca tttctattaa tataactaaa atgattagtc
    40921 gctcatttct caaaaaatct agtctcaatt tataaattaa ggcaatcagt atcaaactaa
    40981 caatccaaaa gattccttgg tttcgaacca actgcaaggc gctcttgcct tcttcaatta
    41041 aaatagcact ggtggtcgaa tagaccacaa tcaagcccaa aatagataaa agcaagtagg
    41101 gaatcaagat ggaataattt aataagtgcc tcttactaat cttcatagca tcaccactct
    41161 actaggatac agacaaatct gttccaaatt ccgttttatt ttctagtttt gattgctatt
    41221 ataccatttt ttcagaaaga aaaaaactct taccttacaa tccttcgaat tttactgttt
    41281 ttcataatta gggcagaatt tgaaatcgta aaaccatttt gaacaagagt tacttcaacc
    41341 cattggctcc gacggattaa gttgctttcg tgaatgccaa aatcagccgc aatttgttca
    41401 taagtgcgct attctcgcat gtattgaata gttaccatga ggagatcgtc taggcttaat
    41461 ttggtttttc gtccaccttt tgcgcgttta cgttgcgttg ataagctgtt tttaacacag
    41521 ctaacatctc gtgcgctgaa cacctacaag gctcttgaaa cggctatcgc ttaattgttt
    41581 acttgcttca tcatccatag ttttattgta ttgtattttt gtttcgcagg aagtctatta
    41641 ttcctttcgt tccaaggttt ttacgctttt agcaacaagc ttacacactc cacgtgatgc
    41701 gtctgtggaa ctcaaaaggt tcggggaacc ttttgaggat taattgcgtt tctctaacaa
    41761 actcacacat ttaacgtggc atgactgatg aagtcatcat aagaatttca cttgctgctc
    41821 ttttacgatg gcagcctgaa cggtcagaag tatcattgta tatcatttgt atcatggcat
    41881 ataaagtatc gctctatttt attgatggtt ttaaaatcgc tcttatcatg gcgagccatt
    41941 caaatttgct ccacaaatga ggaaagtacc attttggact atttaatttt caaagaacaa
    42001 ataaaaaatc tcctcatttt cacactctat gaaattgagg agattatttt ctaaagcgaa
    42061 ttttatcagg aaaatctgtc aattccaata ggtagtctgt actgacatcg taaaagtttg
    42121 agagagttac caatacatct gctgttaacg tatgctcacc ccgttcaatt ttagcataag
    42181 ctgagtttgt aaacgaaagt attttagcta tttgtttttg ggtcaaatcg tgatcttccc
    42241 tcaaatctct caaacgtctg tacatctagc tttctcctga gaaaagtata atatataaaa
    42301 ctaagaaatc attcaaagtg tcctaactgg acattttgaa ctaaaattaa tttattaaac
    42361 atatctcata agcatatcta ttataggtaa gacaatatta agaaagacgg ttaaaaaaca
    42421 acctgactcc actggaattc aggaatcagg tcgcttaaga ttttatatta ttttactgtc
    42481 tacttgacag ggagctgttc accaatggga atctatagct tttttgtgac tgagaactat
    42541 tttatctcag acttcttcaa cacaccttat tattgggcac ttacggaagg ttaatgaatt
    42601 atttaaaata aaagtaaaga gaagcaaaca gacactctat agctgttaga cgctttttag
    42661 agtaataaca atttgataaa gtgaatacaa cttgcttaat taagcgtaag aaaccagaat
    42721 cataaaatca attactttga agtcatgact cacgttgtat tgtttcattg ttaatcgtat
    42781 tcaattattt aattttcgag caacatttaa actagatttt gttctttcaa ttttattagt
    42841 tttggaagaa ggaaaaattc aaatcccata atccagatac
//
LOCUS       DAVMJI010000019        39787 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.019, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000019 DAVMJI010000000
VERSION     DAVMJI010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39787
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.019"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            9..89
                     /locus_tag="VYR58_001159"
     tRNA            9..89
                     /locus_tag="VYR58_001159"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="VYR58_001160"
     tRNA            94..164
                     /locus_tag="VYR58_001160"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="VYR58_001161"
     tRNA            179..251
                     /locus_tag="VYR58_001161"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            265..336
                     /locus_tag="VYR58_001162"
     tRNA            265..336
                     /locus_tag="VYR58_001162"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:297..299,aa:Gln,seq:ttg)
     gene            346..429
                     /locus_tag="VYR58_001163"
     tRNA            346..429
                     /locus_tag="VYR58_001163"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:380..382,aa:Leu,seq:caa)
     gene            536..1813
                     /locus_tag="VYR58_001164"
     CDS             536..1813
                     /locus_tag="VYR58_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV3622325.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1889..3373
                     /locus_tag="VYR58_001165"
     CDS             1889..3373
                     /locus_tag="VYR58_001165"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV3622326.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3434..4714
                     /locus_tag="VYR58_001166"
     CDS             3434..4714
                     /locus_tag="VYR58_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV3622327.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4718..5338
                     /locus_tag="VYR58_001167"
     CDS             4718..5338
                     /locus_tag="VYR58_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV3622328.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5504..6616
                     /locus_tag="VYR58_001168"
     CDS             5504..6616
                     /locus_tag="VYR58_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV3622329.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6939..7364
                     /locus_tag="VYR58_001169"
     CDS             6939..7364
                     /locus_tag="VYR58_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV3622330.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7375..7734
                     /locus_tag="VYR58_001170"
     CDS             7375..7734
                     /locus_tag="VYR58_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV3622331.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATKSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            7841..8485
                     /gene="pcp"
                     /locus_tag="VYR58_001171"
     CDS             7841..8485
                     /gene="pcp"
                     /locus_tag="VYR58_001171"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV3622332.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(8513..9370)
                     /locus_tag="VYR58_001172"
     CDS             complement(8513..9370)
                     /locus_tag="VYR58_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV3622333.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9500..10642
                     /gene="tgt"
                     /locus_tag="VYR58_001173"
     CDS             9500..10642
                     /gene="tgt"
                     /locus_tag="VYR58_001173"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV3622334.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10740..12557
                     /locus_tag="VYR58_001174"
     CDS             10740..12557
                     /locus_tag="VYR58_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV3622335.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12710..13861
                     /gene="nagA"
                     /locus_tag="VYR58_001175"
     CDS             12710..13861
                     /gene="nagA"
                     /locus_tag="VYR58_001175"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV3622336.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14024..15082
                     /locus_tag="VYR58_001176"
     CDS             14024..15082
                     /locus_tag="VYR58_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV3622337.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15233..15598
                     /locus_tag="VYR58_001177"
     CDS             15233..15598
                     /locus_tag="VYR58_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV3622338.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15673..16614
                     /locus_tag="VYR58_001178"
     CDS             15673..16614
                     /locus_tag="VYR58_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV3622339.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16562..17578
                     /locus_tag="VYR58_001179"
     CDS             16562..17578
                     /locus_tag="VYR58_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV3622340.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17580..17906
                     /locus_tag="VYR58_001180"
     CDS             17580..17906
                     /locus_tag="VYR58_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEV3622341.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            17899..18303
                     /locus_tag="VYR58_001181"
     CDS             17899..18303
                     /locus_tag="VYR58_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV3622342.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18308..18568
                     /locus_tag="VYR58_001182"
     CDS             18308..18568
                     /locus_tag="VYR58_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622343.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18531..18992
                     /locus_tag="VYR58_001183"
     CDS             18531..18992
                     /locus_tag="VYR58_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV3622344.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            18970..19416
                     /locus_tag="VYR58_001184"
     CDS             18970..19416
                     /locus_tag="VYR58_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV3622345.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            19519..20106
                     /locus_tag="VYR58_001185"
     CDS             19519..20106
                     /locus_tag="VYR58_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV3622346.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKVILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQARLKVEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20167..21120
                     /locus_tag="VYR58_001186"
     CDS             20167..21120
                     /locus_tag="VYR58_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV3622347.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSNLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21171..22361
                     /locus_tag="VYR58_001187"
     CDS             21171..22361
                     /locus_tag="VYR58_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV3622348.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22510..22881
                     /gene="rnpA"
                     /locus_tag="VYR58_001188"
     CDS             22510..22881
                     /gene="rnpA"
                     /locus_tag="VYR58_001188"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV3622349.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVN"
     gene            22856..23680
                     /locus_tag="VYR58_001189"
     CDS             22856..23680
                     /locus_tag="VYR58_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV3622350.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23699..24685
                     /locus_tag="VYR58_001190"
     CDS             23699..24685
                     /locus_tag="VYR58_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV3622351.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVNAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     ANRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            24736..25359
                     /locus_tag="VYR58_001191"
     CDS             24736..25359
                     /locus_tag="VYR58_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV3622352.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25490..26947
                     /locus_tag="VYR58_001192"
     CDS             25490..26947
                     /locus_tag="VYR58_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV3622353.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIVAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLAAYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            26970..27251
                     /locus_tag="VYR58_001193"
     CDS             26970..27251
                     /locus_tag="VYR58_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV3622354.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQRDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27327..27812
                     /locus_tag="VYR58_001194"
     CDS             27327..27812
                     /locus_tag="VYR58_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV3622355.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            27829..28494
                     /locus_tag="VYR58_001195"
     CDS             27829..28494
                     /locus_tag="VYR58_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV3622356.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            28498..29361
                     /locus_tag="VYR58_001196"
     CDS             28498..29361
                     /locus_tag="VYR58_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV3622357.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29363..30067
                     /locus_tag="VYR58_001197"
     CDS             29363..30067
                     /locus_tag="VYR58_001197"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV3622358.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYRAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30246..31919
                     /locus_tag="VYR58_001198"
     CDS             30246..31919
                     /locus_tag="VYR58_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV3622359.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEQEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32031..33122
                     /gene="ulaG"
                     /locus_tag="VYR58_001199"
     CDS             32031..33122
                     /gene="ulaG"
                     /locus_tag="VYR58_001199"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV3622360.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33236..35212
                     /gene="tkt"
                     /locus_tag="VYR58_001200"
     CDS             33236..35212
                     /gene="tkt"
                     /locus_tag="VYR58_001200"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV3622361.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            35329..35628
                     /gene="yajC"
                     /locus_tag="VYR58_001201"
     CDS             35329..35628
                     /gene="yajC"
                     /locus_tag="VYR58_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV3622362.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35674..36102
                     /locus_tag="VYR58_001202"
     CDS             35674..36102
                     /locus_tag="VYR58_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV3622363.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36104..36514
                     /locus_tag="VYR58_001203"
     CDS             36104..36514
                     /locus_tag="VYR58_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622364.1"
                     /translation="MENLTNFYEKYRVYLTRPRLEILTVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            36814..39465
                     /gene="adhE"
                     /locus_tag="VYR58_001204"
                     /gene_synonym="adhC"
     CDS             36814..39465
                     /gene="adhE"
                     /locus_tag="VYR58_001204"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV3622365.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12126 a         7108 c         8937 g        11616 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttattggggt atagccaagc ggtaaggcaa gggactttga
      301 ctccctcatg cgttggttcg aatccagcta ccccagttac tatttgccgg cgtggcggaa
      361 ttggcagacg cgctggactc aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg
      421 ccgccggtat agtatagtgt taggaacgtt gttattcttc gttccttttt tatattattt
      481 ttggtataat tatagttatt caaattttat ttagattaag aaagtgtagg ggagtatgtc
      541 ttgttctatc gatttattaa aacatcggta tttgaaaaat attaaagaaa atcctgaatt
      601 gtttgtcgga attgagttgg agtatcctgt tgcaagttta gaaggggatg ctacagatgt
      661 tgaagttatg aaggatctat ttcattattt agtttctact ttggatctca ccgtagcaaa
      721 ggtagatgat tttggcaatc tgatccagtt agtagatccg ataagtcagg atgctatttt
      781 atttgaagtt tcctatacaa cgattgagtt tgcatttggt aaggctgaaa cgattcaaga
      841 ggtcgaaaat cgtttcaata attatatgaa tgtaattcag agaaagttag ctgaatcaaa
      901 tcatgctatt gttggctgtg gtatccatcc caactgggat aaaaatgaga attgtccagt
      961 ggcttatcca cgctatcaga tgttgatgga ttatttgaat ttgagtagaa atattattaa
     1021 atcagattta catcatttcc ctgaatatgg tacttttatc tgtgggagcc aggttcagct
     1081 ggatatttca aaaaccaact acttacgggt gattaatgct tttactcaaa ttgaagcggc
     1141 taaggcttat ttatttgcaa actctgaatt ttcgggtgcg gattgggata cgaaaatttc
     1201 aagggatatt ttctgggaag aatctatgca tggtatctat ccagagaatg ttggggtcaa
     1261 tgctagactc cttaatgatg aagctgattt ttttgactat ctaaatcatt ctgcgatttt
     1321 tactgcggaa cgtgatgggc agacctatta tttttatcct attcaggctg gggactattt
     1381 ggctacgtcc gaaatccaag catttgctct gaatggggat gaggttatta tttaccccca
     1441 agagaaggat tttgaaactc atcgtagtta ccagtaccaa gatttaacga ctcgaggaac
     1501 agttgagttt cgtagtgtgt gtacacagcc acttgatagg acttttgctt ctgcagcttt
     1561 tcacttggga ttattggtta atttagacaa gttagaagct tacttagaaa cagcaccttt
     1621 ctttaaagta tttggttatg attacaagtc tttaaggaga caattttcta agaaaaatct
     1681 tacagatgag gaagaaacta cgattattga attttccaaa gacttactcc tactagctga
     1741 ggagggacta gtggtgagaa ataaggaaga aatgacctat ttacagcctt tgagagaaga
     1801 attgagccta taatttctct tataaaggga gaattttctg aaaaatcatg atataatgga
     1861 cgagactata gataaaggat agagagtaat gacattagtt tatcaatcaa cgcgtgatgc
     1921 caacaataca gtaactgcca gccaagcaat tttgcaaggt ttggcgacgg acggcggttt
     1981 gtttacaccg gatacttatc caaaggtaga tttgaacttt gacaaattga aagatgcttc
     2041 ttaccaggaa gttgctaagc tagttttgtc agcattttta gatgacttta cagttgagga
     2101 gttggactac tgtatcaaca atgcctacga tagcaaattt gatactccag ctattgcacc
     2161 attagtgaaa ttagatgggc aatacaattt ggaacttttc catggttcaa cgattgcctt
     2221 taaggatatg gccttgtcta ttttgccata ctttatgacg actgctgcta agaaacatgg
     2281 tttggagaac aagattgtta tcttgacagc gacatctggt gacacgggga aagctgctat
     2341 ggcggggttt gcgaatgtgc ctggtactga gattatcgtc ttttatccaa aggatggtgt
     2401 cagcaagatt caagagttac aaatgaccac tcagactggc gacaatactc atgttattgc
     2461 tattgatggt aactttgacg atgcgcaaac aaatgtgaag cacatgttta acgacgtggc
     2521 tcttcgtgaa aaattgacta ccaacaagtt gcaattttca tcagctaact ctatgaacat
     2581 tggtcgtctg gtgccacaaa ttgtttatta tgtttatgct tacgctcaat tggttaagac
     2641 tggtgaaatt gtagctggtg aaaaggttaa cttcacagta ccaacaggaa actttggaaa
     2701 tatcttggct gccttttatg ccaaacaaat tggtttgcca gttggtaaat taatctgtgc
     2761 ttcaaatgac aacaatgttt tgacagactt ctttaaaaca cgtgtctatg acaaaaaacg
     2821 tgagtttaag gtaacaacca gcccatctat ggatatcttg gtatcttcaa acttggagcg
     2881 cttgattttc catcttttgg gaaataatgc tgaaaagaca actgaactta tgaatgcctt
     2941 gaacacgcaa ggacaatata agttgacaga ctttgatgca gagattttgg acctctttgc
     3001 agctgaatat gcgactgagg aagaaacggc agcagagatc aagcgtgttt gtgagttaga
     3061 ttcttatatc gaggaccctc atacagctgt tgcttcagca gtttataaaa aataccaatc
     3121 ggccactgga gatgtaacta agacagtgat tgcttcaaca gctagtccat acaagttccc
     3181 agtagttgca gtagaagctg taactggaaa agcaggttta acagactttg aagccttggc
     3241 tcaattacat gaaatctcag gcgttgcagt gccaccagca gttgatgggc ttgaaatagc
     3301 tccaattcgt cacaagacaa cagtggcagc tgctgacatg caagcagcgg ttgaggctta
     3361 tttaggactt taagacagag ggagcaaact cggttgggaa accaactgag tttcttttca
     3421 tcaggaggag agattgttta agaaaaataa agacattctt aatattgcat tgccagctat
     3481 gggtgaaaac tttttgcaga tgctaatggg aatggtggac agttatttgg ttgctcattt
     3541 aggattgata gctatttcag gggtttcagt agctggtaat attatcacca tttatcaggc
     3601 gattttcatc gctctgggag ctgctatttc cagtgttatt tcaaaaagca tagggcagaa
     3661 agaccagtcg aagttggcct atcatgtgac tgaggcgttg aagattacct tactattaag
     3721 tttcctttta ggatttttgt ccatcttcgc tgggaaagag atgataggac ttttggggac
     3781 ggagagggat gtagctgaga gtggtggact gtatctatct ttggtaggcg gatcgattgt
     3841 tctcttaggt ttaatgacta gtctaggagc cttgattcgt gcaacgcata atccacgtct
     3901 gcctctctat gttagttttt tatccaatgc cttgaatatt cttttttcaa gtctagctat
     3961 ttttgttctg gatatgggga tagctggtgt tgcttggggg acaattgtgt ctcgtttggt
     4021 tggtcttgtg attttgtggt cacaattaaa actgccttat gggaagccaa cttttggttt
     4081 agataaggaa ctgttgacct tggctttacc agcagctgga gagcgactta tgatgagggc
     4141 tggagatgta gtgatcattg ccttggtcgt ttcttttggg acggaggcag ttgctgggaa
     4201 tgcaatcgga gaagtcttga cccagtttaa ctatatgcct gcctttggcg tcgctacggc
     4261 aacggtcatg ctgttggccc gagcagttgg agaggatgat tggaaaagag ttgctagttt
     4321 gagtaaacaa accttttggc tttctctgtt cctcatgttg cccctgtcct ttagtatata
     4381 tgtcttgggt gtaccattaa ctcatctcta tacgactgat tctctagcgg tggaggctag
     4441 tgttctagtg acactgtttt cactacttgg gacccctatg acgacaggaa cagtcatcta
     4501 tacggcagtc tggcagggat taggaaatgc acgcctccct ttttatgcga caagtatagg
     4561 aatgtggtgt atccgcattg ggacaggata tctgatgggg attgtgcttg gttggggctt
     4621 gcctggtatt tgggcagggt ctctcttgga taatggtttt cgctggttat ttctacgcta
     4681 tcgttaccag cgctatatga gcttgaaagg ataggaaatg caaaaaacag cttttatttg
     4741 ggatttagac gggactttat tggactctta cgaagcgatt ttatcaggga ttgaggagac
     4801 ttttgctcag ttttctattc cttatgataa ggagaaggtg agagagttta tcttcaagta
     4861 ttcggtgcaa gatttgcttg tgcgggtggc agaagataga aatctggatg ttgaggtgct
     4921 aaatcaggtg cgtgcccaga gtctggctga gaagaatgct caggtagttt tgatgccagg
     4981 tgcgcgtgag gtgctagctt gggcagacga atcaggaatt cagcagttta tatatactca
     5041 taaggggaac aacgctttta ccattctcaa ggacttgggg gtggaatcct attttacaga
     5101 gattttaacc agtcagagtg gctttgtgcg gaagccaagt ccagaagcgg ctacctatct
     5161 gctagataag tatcagttga attctgataa tacttattat ataggggatc ggactctgga
     5221 tgtggaattt gcccagaata gtgggattca aagcatcaac tttttagagt ctacttatga
     5281 agggaatcac aggattcaag cgttagcaga tatttcccgt atttttgaga ctaagtgata
     5341 aaaagattgt gtcagttttg tgacagagac ctaacaaact atttcaagta acctagtttg
     5401 ttacaaggaa tagacagttc tgttaaatag gcccgagagg gctttttttc tacatttttt
     5461 gtgttatgat agacaggtac tcatttgaaa ggaatttgaa agaatgaaga aaagaatgtt
     5521 attagcgtca acagtagcct tgtcatttgc cccagtattg gcaactcaag cagaagaagt
     5581 tctttggact gcacgtagtg ttgagcaaat ccaaaacgat ttgactaaaa cggacaacaa
     5641 aacaagttat accgtacagt atggtgatac tttgagcacc attgcagaag ccttgggtgt
     5701 agatgtaaca gtgcttgcga atctgaacaa aatcactaat atggacttga ttttcccaga
     5761 aactgttttg acaacgactg tcaatgaagc agaagaagta acagaagttg aaatccaaac
     5821 acctcaagca gactctagtg aagaagtgac aactgcgaca gcagatttga ccactaatca
     5881 agtgaccgtt gatgatcaaa ctgttcaggt tgcagacctt tctcaaccaa ttgcagaagt
     5941 tacaaagaca gtgattgctt ctgaagaagt ggcaccatct acgggcactt ctgtcccaga
     6001 ggagcaaacg accgaaacaa ctcgcccagt tgaagaagca actcctcagg aaacgactcc
     6061 agctgagaag caggaaacac aagcaagccc tcaagctgca tcagcagtgg aagtaactac
     6121 aacaagttca gaagcaaaag aagtagcatc atcaaatgga gctacagcag cagtttctac
     6181 ttatcaacca gaagagacga aaataatttc aacaacttac gaggctccag ctgcgcccga
     6241 ttatgctgga cttgcagtag caaaatctga aaatgcaggt cttcaaccac aaacagctgc
     6301 ctttaaagaa gaaattgcta acttgtttgg cattacatcc tttagtggtt atcgtccagg
     6361 agacagtgga gatcacggaa aaggtttggc tatcgacttt atggtaccag aacgttcaga
     6421 attaggggat aagattgcgg aatatgctat tcaaaatatg gccagccgtg gcattagtta
     6481 catcatctgg aaacaacgtt tctatgctcc attcgatagc aaatatgggc cagctaacac
     6541 ttggaaccca atgccagacc gtggtagtgt gacagaaaat cactatgatc acgttcacgt
     6601 ttcaatgaat ggataaaccc gacttgataa catcattttg acgaatgaga tctagctttc
     6661 gtgatggaaa gcgattctcg ttcgtttttt ctttgtcata ctcttcgaaa atctcttcaa
     6721 accacgtcag ttttatctga aacttcaaag ctgtgctttg agcaacctgc gactagcttc
     6781 ctagtttgct ttttgatttt cattgagtat caatttgaat ggaaaatgga aagttatcat
     6841 cttgtaatga gttaagcaac attcttgcaa tctattttac tttatatcac aattaattag
     6901 tcaaatattg ataaatcaat aaaaagagag gggaagaaat gctagagatt caagatttac
     6961 tgtatcaact ccgcttgtct gagcaagcga gtacgcaatt gtttgaaaaa aggcttggga
     7021 ttagtttgac acggtatcag attttactgt ttttgctgga gcattctcct tgtaaccaaa
     7081 tggcggttca ggagcgtttg aaaattgatc aggctgcttt gacacggcat ttcaaaattt
     7141 tggaaacgga aggtttggtg gagcgtcatc gtaatcctga aaatcagcgg gaagtgttgg
     7201 tagaggctgc gaagtatgcc aaggagcagt tagtggtgaa tccccctctg caacatatca
     7261 gggttaagga agagatagaa agtatcttaa cagagtttga gagaacagaa ctcagccgtt
     7321 tattaaataa attggttttg ggtattgaaa atatagaaat ttaaggagaa atagatgtca
     7381 attattttaa caacgatcgt tgctttggag catttttaca ttttttattt ggaaagtatt
     7441 gccacgaaat cagatgcgac tagtcgtgta tttaatatgg aaaaggaaga attggctcat
     7501 ccgtcagtaa gttcattgtt caaaaatcaa ggaatttata aggctctgct aggagtcttt
     7561 ctcttgtatg tcatttattt ctcacagaat ttagaaattg tgactatttt tgtcttattt
     7621 gtgattggtg ctgcgactta cggctcttta acagcggata aaaaaattat tttgaaacaa
     7681 ggtggatcag ctattttggc cttgattagt attttactct ttaaatacac ttgaaggtcg
     7741 attctaatct cgctaatcct ttttaatcca gaataaggga aatatgttat acttgttttt
     7801 aagaaaaaag tctcattgaa ttggttttga ggagttagaa atgaaagtat tagtgacagg
     7861 ttttgagccc tttggagggg aaaagggcaa tccagctttg gaggccatta aaggtttacc
     7921 agctgaaatc catggtgctg aggtccgttg gctagaggtg ccgacagttt ttcacaaatc
     7981 tgctcaagta ttggaagaag agatgaatcg ttatcaacct gactttgtcc tttgtattgg
     8041 gcaagctggt ggaagaacta gtttgacacc tgaacgagtg accattaatc aagacgatgc
     8101 atgcatttct gataacgaag ataatcaacc gattgaccgt cccattcgcc cagatggtgc
     8161 ttcggcctac tttagtagtt tgccgattaa agcgatggtt caagctataa aaaaagaggg
     8221 cttaccggcc tctgtttcca atacggcagg gacttttgtc tgcagccatt tgatgtatca
     8281 ggctctctat ttggtagaaa agaaatctcc atatgttaag gcaggtttta tgcatattcc
     8341 ttatatgatg gaacaggtgg tgaacagacc gactactcca gctatgagtt tagtggatat
     8401 tcggcgaggg atagaagcag caatcggcgc tataatagaa catggagatc aggaactcaa
     8461 gttggtaggc ggagaaactc attgatagaa aaaagcttga ggggaaaaac cttcaagctt
     8521 ttggacgttt tcgggccaat actgctcggt aaaacataat tttagtgcat tggatataag
     8581 gtaggagtga aaaactagca atgccaaagg taatccaatt gaggaagtac caaggaagaa
     8641 gctgtaaatc taggacaaag tgctggaact tgtagccctt cataaaggaa cggctagttt
     8701 ttaggattcg tcttggtggg acctgtccta ggtctagact ataacagaga agaaattcca
     8761 cctgtgaata ggcataatac tgtggaatat agaggatatt tcctacaatg atcaagatga
     8821 gacttgcaag aaagtagagt ccaaagacca tgaggaaacg ctcggtttca actgatgaga
     8881 gatctagatt tggaaactca ggatgtaggg tgacgaattt tttggctaaa aagctactat
     8941 aaaagaggag gtaaatccca agtaaattag ggatactcca taaaaagaga tagaaacgtt
     9001 tgagaagtag ggtcaaaaag gtttgagaaa agcgctcctc atcaaagaga gctaggctgt
     9061 tttttacaga tggctccgtt ttagaatctt tcatgagtgt cagtgttgca tagacggaac
     9121 tggtcaaaag aatagtcccg ataaaggaga ctagtagagg aaagaggtag gtttgaagta
     9181 tttggccaag tatgctgaaa aatggctgtt ctaaaacagt cccgtggatc cgagataagg
     9241 gattaagaaa accagataag atgaccagca tactgggaag gatatagagg agaaagagac
     9301 ggggggtgtc agcctgaaaa tgttttgact cctgacgaat tgtttttaaa tcaatttttg
     9361 gatagttcat tctcttatta taccatagtt cttatacata gttcgtgaca gttcctactt
     9421 tttttgataa aatcatacag tgtgtccttg ggcacactgt atgaactggg actgtctttc
     9481 ccagcttcgg aggtaaaaaa tgtcagattc accaatcaaa tatcgtttga ttaagaaaga
     9541 aaaacacaca ggagctcgtc tgggagaaat catcactccc cacggtacct ttccgacacc
     9601 tatgtttatg ccagttggga cacaagccac tgtcaaaact cagtcacctg aagaattgaa
     9661 ggagatgggt tcgggaatta tcctatcaaa cacctatcat ctctggcttc gccctggaga
     9721 tgaactcatt gcacgcgctg gtggtctcca caagttcatg aattgggacc agcctatctt
     9781 gacagatagt ggtggttttc aggtttattc tttagcagat agccgtaata tcacagaaga
     9841 aggagtaacc tttaaaaatc atctaaatgg ttctaagatg ttcctatccc cagaaaaagc
     9901 catctctatt cagaataatc tgggttcaga catcatgatg tcctttgatg aatgtcctca
     9961 gttttatcaa ccttatgact acgttaagaa atcgatcgag cgtaccagcc gttgggctga
    10021 gcgtggtttg aaggctcacc gtcgtccaca tgaccaaggt ttgtttggaa ttgtgcaagg
    10081 tgcaggattt gaagaccttc gccgccaatc agctcatgat cttgtcagca tggatttctc
    10141 aggctactct atcggtggtt tggcagtggg agaaacccat gaagagatga atgcggtctt
    10201 ggactttaca actcaactgc tacctgaaaa taaacctcgt tatctgatgg gtgtgggagc
    10261 gccagatagc ttgatcgatg gggtcattcg tggggtggat atgtttgact gtgtcttacc
    10321 gactcgaatt gctcgtaacg ggacttgtat gaccagtcaa ggacgtttgg ttgtgaaaaa
    10381 tgcccagttt gctgaggact ttacgccact ggatcctgag tgtgactgct acacatgtaa
    10441 taactataca cgcgcttacc ttcgtcacct gctcaaggct gatgaaacct ttggtatccg
    10501 cttgactagc taccacaatc tttacttctt gcttaacctg atgaagcaag tgcgacaagc
    10561 catcatggat gacaatctct tggaattccg tgagtatttt gtggaaaaat atggctataa
    10621 taagtcagga cgtaatttct aaaatggaat tgatataaaa aaatcctaag ttttctctta
    10681 ggatttttct tctttttttg atagaataaa gtgtacaatg aaaggaagaa taaactcgta
    10741 tgcgcattaa atggttttcc ttgattagga ttataggttt acttttggta ctcttgtatc
    10801 acttctttca gacgatcttt cctggaggat ttttcggggt agatgtcttt ttcacatttt
    10861 caggtttcct gattacagct ctactcattg aagaattttc taagaacaat gagattgatt
    10921 tgataggatt ttttagaaga cgcttttatc ggattgtgcc acctgtggtt ttgatggtct
    10981 tggtgaccat gccttttact ttcttggttc gccaagacta tgttgctgga attggtggcc
    11041 agattgcggg cgtcttaggc tttatgacca acttctatga actcctaaca ggtgggagtt
    11101 atgaatctca gttcattcct catttgtttg ttcataattg gagtttggca gttgaggttc
    11161 actactatat tctttgggga ttggcagttt ggttcttatc caaacaagct aaatcaaatg
    11221 gtcagttgaa ggggatggtc tttctcttat ctgctgctgc cttcttgatc agtttcttct
    11281 ccatgtttat tggtagtttt ctagtgacct cttattcctc tgtttatttc tccagtttaa
    11341 ctcatgtcta tccattcttt ttgggaagta tgttagcaac tattgtaggt gttcgtcaga
    11401 cgacttccct cgtcaagcag ttggataaaa tctgggattt acgaaagact ttggtagttt
    11461 ttggaggagg ctttggtttc ctagttcttt tgactttctt tgtcaaattc acttatcttt
    11521 ttgcctatct tatcggcttc ttgcttgcca gtcttgcagc tcttgccatg attctggcgg
    11581 cgcgtgtctt acatgaaaag acacatcata tacaggagcc gaagattatc agctttttag
    11641 cggatactag ctatgcggtt tatcttttcc attggccttt ctatatcatt ttctcacagt
    11701 tgacatcaaa tcttcttgct gtattactga ctctgatttg ttcttatggc tttgccagtc
    11761 tgtcattcta tgtattggaa ccttggattg caggcaagaa cacacctatt ttacaaactc
    11821 ttcgtcccct gccttatatt cacgcaattc ttgtagcagg tacaggaatc ttgaccatca
    11881 ttgtctgcac ggtgaccttg ttggcaccac aagtgggagc gtttgagaca gacttgactg
    11941 tcaatggctt gaagcaagct gcaacaaata ttggccagac caaggtgatg gcagaacggg
    12001 cagatgcaaa cagtttggga attgctgatg gcactatgtt aattggtgac tcagtggctt
    12061 taagggcaaa tacagcacta cagacagctc ttcctggagc acagattaac gcgcaggtca
    12121 gcgtaacaac caagaccgca aatgaaatca tgctaaataa tagccagaat aaatttttac
    12181 ctaagacggt ggtcattgcg actggggtaa ataatcctga gaattacaag gatgactggg
    12241 acagtatcgt gaaaaatctt cctaagggac accatatgat tttggtgact ccttatgagg
    12301 gagataagac aaaagagacc tatgccatcg ttgagaaggc tgctgcctat atgagagaat
    12361 tggcagagaa gacaccttac attacgatag cagattggaa tcaagttgcg aaagagcatc
    12421 cagaaatttg ggctggaaca gaccaggttc atttcgggag tgagagtagc actatcgaag
    12481 caggagcaaa attgtatgca gatacgattg ccacagcttt gcagacagct caagacaagc
    12541 cggttaaatc aaaataactt gtattaaaaa agagaagagt tggagaaatc cagctctttt
    12601 aaaatatctc caaaaaatag gtctatacca tttacaaata aaaaagaaag gtttataatg
    12661 taattgacat aataaattgt agaatcaatc ttttaaggag gttaacatta tgcctaacta
    12721 tattaaagcg gatcagtttt tctacccaca cggagttcgt cgaggtggtt acttggaact
    12781 tgtggacggc aagtttggga aacatgtaga gcagattcct gaaggggctg aggtgattga
    12841 ctatacaggt tatagcattg ccccaggtct tgtggatact catattcatg gatatgcagg
    12901 tgtagatgtg atggacaaca acattgaagg tacattgcat actatgagtg aaggacttct
    12961 tagtaccggt gttaccagtt tcttacccac aactttaaca gccacttatg agcaattgct
    13021 tgcagtcact gaaaatcttg gaaaccatta taaagaagca acaggtgcta agattcgtgg
    13081 gatttattat gaaggtccat atttcacaga aacttttaag ggggcacaaa atccaactta
    13141 tatgagagac ccgggtgttg aggagtttca ttcttggcaa aaagcggcaa atggcttgct
    13201 taataaaatt gcccttgcac cagaacgtga tggggtggaa gactttgttc gtacagttac
    13261 gggcgaaggt gtgacggttg ctcttggaca ttcaaacgcg acttttgatg aagccaaaaa
    13321 agcagtcgat gctggagcga gtgtttgggt gcatgcctac aatggaatgc gtgggttgac
    13381 tcaccgtgaa ttgggtatgg ttggagccat gtaccaattg ccacatacct atgcagagtt
    13441 gatctgtgat ggtcaccacg tagatccaaa ggcttgcgaa attcttatca aacaaaaagg
    13501 aacagaaaac atcgctctta tcacagactg tatgacagct gggggattgg aagacggaga
    13561 ttatatgttg ggagaattcc cagttgtcgt tgcaaatgga actgcacgcc tcaaatcgac
    13621 aggtaacttg gcaggttcta tcctcaaact caaagatggt ttgaagaatg tggtcgaatg
    13681 gggaattgcg aatccgcatg aagcagtcat gatggccagc ttcaacccag ctaaatccgt
    13741 tcacatcgat gacgtctgtg gccaaatccg tgaaggctac gacgctgact tcatcgtatt
    13801 agataaagat ttggaattgg tagcaaccta tctagatggc gtaaaacgtt atcaagcata
    13861 agagagaagg cagaagttag agactagctt ctgctttttt atacagggta ctttactggt
    13921 aaataaaaag ttaaaaaaat cacaaaaaaa gcttgaagaa acaaagaaaa aggcttacaa
    13981 ttgaactata aatattacaa ataaaaaaac ggaggagtgc tttatgaaag cctatactta
    14041 tgttaaacca ggacttgctt cttttgttga tgtagacaaa ccagttattc gcaagccaac
    14101 agacgctatt gtgcgtattg taaaaaccac tatttgtgga acagacctcc atattatcaa
    14161 aggggatgtt cctacttgcc aaagtggtac cattcttggc cacgaaggga ttgggattgt
    14221 tgaagaagtt ggggaaggag tttccaactt caaaaaaggc gacaaggtct tgatttcttg
    14281 cgtctgtgcc tgtggtaaat gctactactg taaaaaagga atttatgccc actgtgaaga
    14341 cgaagggggc tggattttcg gtcacttgat tgatggtatg caggctgaat atctacgtgt
    14401 ccctcatgca gataatactc tttaccatac tccagaagac ttgtcagatg aagctttggt
    14461 tatgctgtca gacattctgc ctactggata tgaaattggt gtcttaaaag ggaaagtaga
    14521 acctggttgc agcgtagcca ttattggttc aggtccagtt ggattggctg ctcttttaac
    14581 agcccaattc tattcaccag ctaaattgat tatggtagac ctagacgata accgcttgga
    14641 aactgcccta tcattcggtg cgactcataa ggttaattct tcagacccta aaaaagccat
    14701 taaagaaatt tatgatttga cagatggtcg tggtgtggat gtcgctatcg aagctgtagg
    14761 gattcctgaa acatttgatt tctgtcaaaa gattatcggt gtagacggaa cggttgccaa
    14821 ctgtggtgtg catggtaaac cagttgaatt cgatttagat aaactttgga ttcgcaacat
    14881 caatgtaaca actggtttgg tatctacaaa tacgactcca caattgttga aagcacttga
    14941 aagtcataag attgaaccgg aaaaattggt aactcactat ttcaaactca gtgaaattga
    15001 aaaagcctac gaagtcttca gtaaggcagc agaccaccat gccattaagg tcattatcga
    15061 aaacgatatc tcagaagcct aagtagtaaa aatatttttg tacataagta aatagaaatt
    15121 cagtcatcca tcagatggtt ggatttttta tcaaaaaatt aagaaatgag catatttctt
    15181 tccttgtctg gcggaattgg ttataatata cggtacaaag gaatgaatga atatgtatcg
    15241 tgttatagaa atgtacggag attttgaacc gtggtggttc ttagaaggtt gggaagaaga
    15301 tattgtagca agtagaaaat ttgaccagta ttatgatgct ctcaaatact acaaaacttg
    15361 ctggtttaga ttggaacaag aatcgcctct ttataaaagt agaagcgact tgatgaccat
    15421 tttttgggac ccggaagacc aacgctggtg tgatgaatgt gatgagtatt tacaacaata
    15481 ccattctttg gctcttttgc aggatgagca ggttatccca gacgaaaaac tacgctcagg
    15541 ctatgaaaaa caaaccagtc aggaaaggaa tcgttcttgc cgtatgaaat taaaatagag
    15601 aaaagtaact ttttggagtt gcttttttta tttttctaac gctttgcgaa tagtataggt
    15661 gaggaggtaa gtatggttca agaaattgca caagaaatca ttcgttcggc tcggaaaaaa
    15721 ggggcgcaag acatttattt tgtccccaag ttagatgcct atgagcttca tatgagggta
    15781 ggagacgagc gctgtaaaat tggtagctat gattttgaaa agtttgcagc cgttatcagt
    15841 cactttaagt ttgtggcggg tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc
    15901 tgtgattatg cctatgacca gaagatggcg tctctacgtt tatctactgt aggcgattat
    15961 cgggggcatg agagtttggt tatccgtttg ttgcacgatg aggagcagga cttgcatttt
    16021 tggtttcagg atattgaaga attaggcaag cagtacaggc aacggggact ctatcttttt
    16081 gctggtccgg ttgggagtgg taagacgacc ttgatgcatg aattgtccaa gtcactcttt
    16141 aaaggacagc aagttatgtc catcgaagat cctgtcgaaa tcaagcagga cgacatgctt
    16201 cagttgcagt tgaacgaagc aatcggccta acctatgaaa atctaatcaa actttccttg
    16261 cgtcatcgac cagatctctt gattatcgga gaaattcgtg acagcgagac ggcgcgtgca
    16321 gtggtcagag ctagtttgac aggtgcgaca gtcttttcaa ccattcacgc caagagtatc
    16381 cgaggtgttt atgagcgtct gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt
    16441 ctgcaaggag tctgctacca gagattaatc gggggaggag gaatcgttga ctttgcaaac
    16501 agagattatc aagaacacca agcagccaag tggaatgagc aaattgacca gcttcttaaa
    16561 gatggacata tcacaagtct tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa
    16621 aaatatcatc accctattta acaatctctt ttctagcggt tttcatctgg tggagactat
    16681 ctccttttta gataggagtt ccttgttgga caagcagtgt gtgacccaga tgcgtacagg
    16741 cttgtctcag gggaaatcat tctcagaaat gatggaaagt ttgggatgtt caagtaccat
    16801 tgtcactcag ttatctctag ctgaagttca tggcaatctt cacctgagtt tgggaaagat
    16861 agaagaatat ctagacaatc tggccaaggt caagaaaaag ttaattgaag tagcgaccta
    16921 tcctttgatt ttgctgggtt ttcttctctt aattatgctg gggctacgga attacctgct
    16981 cccacaactg gatagtagca atattgccac ccgaattatc ggtaatctgc cacaaatttt
    17041 tctaggcatg gtagggcttg tttccgtgct tgccctttta gcactaactt tttataaaag
    17101 aagttctaag atgagtgtct tttctatctt agcacgcctt ccctttattg gaatctttgt
    17161 gcagacctac ttgacagcct attatgcacg tgaatggggg aatatgattt cacagggaat
    17221 ggagctgacg cagatttttc aaatgatgca ggaacaaggt tcccagctct ttaaagaaat
    17281 cggtcaagat ctggctcaaa ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac
    17341 ctatcctttc tttaggaagg aattgagtct catcatagag tatggggaag ttaagtccaa
    17401 gctgggtagt gagttggaaa tctatgctga aaaaacttgg gaagcctttt ttacccgagt
    17461 caaccgcacc atgaatttgg tgcagccact ggtttttatc tttgtggcac tgattatcgt
    17521 tttactttat gcggcaatgc tcatgcccat gtatcaaaat atggaggtaa atttttaaaa
    17581 tgaaaaaaat gatgacattc ttgaaaaaag ctaaggttaa agcttttaca ttggtggaga
    17641 tgttagtagt cttgctgatt atcagcgtgc ttttcttgct ctttgtacct aatctgacca
    17701 agcaaaaaga agcagtcaat gacaaaggaa aagcagctgt tgttaaggtg gtggaaagcc
    17761 aggcagaact ttatagcttg gataaaaatg aagatgctac tctgagcaag ttacaaggag
    17821 atgggcgcat cacggaagaa caggttaaag cttataatga atactatact aaaaatggag
    17881 gggcaaatcg taaagtcaat gattaaggcc tttaccatgc tggaaagtct cttggttttg
    17941 ggacttgtga gtatccttgc cttgggctta tccagctctg tccagtccac ttttgcagca
    18001 gtagaggagc agattttctt tatggagttt gaagaactct atcgggaaac ccaaaaacgc
    18061 agtgtagcca gtcagcaaaa gactagtcta aatttagatg ggcagacgct tagcaatggc
    18121 agtcaaaagt tgacagttcc taaaggaatt caggcaccat caggccaaag tattacattt
    18181 gaccgagctg ggggcaattc gtccctggct aaggttgaat ttcagaccag taaaggagcg
    18241 attcgctatc aattatatct aggaaatgga aaaattaaac gcattaagga aacaaaaaat
    18301 tagggcagtg attttactgg aagcagtagt cgctctagct atctttgcca gcattgcgac
    18361 cctccttttg ggacaaattc aaaaaaatag gcaagaggaa gcaaaaatct tgcaaaagga
    18421 agaagtcttg agggtagcta agatggccct gcagacgggg caaaatcagg taagcatcaa
    18481 cggagttgag attcaggtat tttctagtga aaaaggattg gaggtctacc atggttcaga
    18541 acagttgttg gcaatcaaag agccataagg tcaaggcttt taccttgtta gaatccctgc
    18601 ttgccctcat tgtcatcagt gggggattac tcctttttca aactatgagt cagctcctca
    18661 tttcagaagt tcgctaccag caacaaagcg agcaaaagga gtggctcttg tttgtggacc
    18721 aacttgaggc agaattagac cgttcgcagt tcgaaaaagt agaaggcaat cgcctataca
    18781 tgaagcaaga tggcaaggac atcgccatcg gtaagtcaaa gtcagacgat tttcgtaaaa
    18841 ccgatgctag tggacggggg tatcagccta tggtttatgg cctcaaatca gctcagatta
    18901 cagaggacaa tcaactggtt cattttcgtt tccagtttca aaaaggctta gaaagggagt
    18961 tcatctatcg tgtggaaaaa gaagaaagtt aaggcaggtg ttctcctcta cgcagtcacc
    19021 atagcagcca tctttagtct tttgttgcaa ttttatttga accgacaaat cgcccactat
    19081 caagactatg ctttaaataa agaaaaattg gttgcttttg ccatggctaa acgaaccaag
    19141 gataaagccg agcaagaaag tggggaacag gtttttaatc taggtcaggt aagctatcaa
    19201 aacaagaaaa caagcttggt gacgactgtt cgtacgtcta agagccaata tgagtttctg
    19261 tttccttcag tcaaaatcaa agaagagaaa agagataaaa aggaagaggt agcgaccgat
    19321 tcaagcgaaa aagcggagaa aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct
    19381 agtcaattca actataatgc gttgaatcca gaatagtcca ctgtagtttc tagaaaattg
    19441 ctggaaatgg atgttaagct ccaattcatt tgtttatatc ttatttcagt ttactatact
    19501 ttgtgctaaa ctaaagatat gaaacatgat tttaaccaca aagcagaaac tttcgactcc
    19561 cctaaaaata tcttcctcgc aaacttggta tgtcaagcag tcgagaaaca gattgatatt
    19621 ttatcagaca aagtaatttt agatttcggt ggtggcacgg gtctattagc cttgccccta
    19681 gccaagcagg ctaagtcagt tactcttgta gacatttctg agaaaatgtt ggagcaagct
    19741 cgtttgaaag tggagcagca agcaatcaag aatatccagt ttttggagca agatttaccg
    19801 aaaaatccct tggagaaaga gtttgattgc cttgctgtta gtcgggttct tcatcatatg
    19861 cctgatttgg atgcggctct ctcactgttt catcaacatt tgaaggaaga tgggaaactc
    19921 atcattgctg attttaccaa gacagaagct aatcatcatg gatttgattt agctgaactg
    19981 gaaaacaagc taattgagca tggtttttca tctgtgcata gtcagattct ctatagcgct
    20041 gaagacctgt ttcaaggaaa tcactcagaa ttctttttaa tagtagccca aaaatcactc
    20101 gcctagtcag ggagtgattt ttctataagg atggaaaaaa gaagggaaat ttgataagat
    20161 aggaatatgg attttgaaaa aattgaacaa gcttatacct atttactaga gaatgtccaa
    20221 gttatccaaa gtgatttggc gaccaacttt tatgacgcct tggtggagca aaacagcatc
    20281 tatctggatg gtgaaactga gctaaaccag gtcaaagaca acaatcaggc ccttaagcgt
    20341 ttagcactac gcaaagaaga atggctcaag acctaccagt ttctcttgat gaaggctggg
    20401 caaacagaac ccttgcaggc caatcaccag tttacaccag atgccattgc tttgcttttg
    20461 gtgtttattg tggaagagtt gtttaaagag gaggaaatta ctatcctcga aatgggttct
    20521 gggatgggaa ttctaggcgc tactttcttg acctcgcttg ataaaaaggt ggattacttg
    20581 ggaatggaaa tggatgattt gctgattgat ctggcagcta gcatggcaga tgtaattggt
    20641 ttgcaggctg gctttgtcca aggagatgcc gttcgtccac aaatgctcaa agaaagcgat
    20701 gtggtcatca gtgacttgcc tgttggctat tatcctgatg atgccgttgc gtcgcgccat
    20761 caagttgctt ctagccaaga acatacttac gcccatcact tgctcatgga acaagggctt
    20821 aagtacctca agtcagacgg atacgctatt tttctagctc cgagtaattt gttgaccagt
    20881 cctcaaagtg atttgttaaa agaatggctg aaagaagagg cgagtctggt tgctatgatt
    20941 agtctgcctg aaaatctctt tgctaatgcc aaacaatcta agactatttt tatcttacag
    21001 aagaaaaatg aaatagcagt agagcctttt gtttatccac ttgctagctt gcaagatgca
    21061 agtgttttaa tgaaatttaa agaaaatttt caaaaatgga ctcaaggtac tgaaatataa
    21121 aatagatttt gttataatag ttgaaaacgc ttaaaaaggg gtatcatgtt atgacaaaaa
    21181 caattgcaat caatgcagga agttcaagtt tgaaatggca attatactta atgccagaag
    21241 aaaaagtgtt agccaaaggt ttgattgaac gtatcggttt gaaagattca atttcaactg
    21301 taaaatttga cggccgttct gagcaacaaa ttttggatat tgaaaatcat acacaagccg
    21361 ttaaaatttt attggatgac ttgattcgtt tcgatattat caaggcttat gacgagatta
    21421 caggtgttgg acatcgtgtt gttgctggtg gagaatattt caaagaatca acagttgttg
    21481 agggagatgt tttagaaaaa gttgaagagt tgagtttgtt ggctcctcta cacaacccgg
    21541 ccaatgcagc aggtgttcgt gccttcaagg aattgttgcc agacattacc agtgtagttg
    21601 tttttgatac ttccttccac acaagtatgc cagagaaagc ttatcgctac cctctaccaa
    21661 caaaatatta cacagaaaac aaggttcgta aatacggtgc tcatggtaca agtcaccagt
    21721 ttgtagcagg agaagctgca aaactcttgg gacgtccatt agaagacttg aagttaatta
    21781 cctgtcatat tggtaacgga ggctcaatta cagctgtgaa agccggcaaa tctgtagaca
    21841 cttctatggg gttcactcct cttggtggta ttatgatggg aacgcgtaca ggggatattg
    21901 atccagctat cattccttat ttaatgcaat atacagagga ttttaacaca ccagaagata
    21961 tcagtcgtgt tcttaaccgt gaatcaggtc ttttgggagt ttctgctaat tctagcgata
    22021 tgcgcgatat agaagcagct gtagcagaag ggaatcacga ggctagcttg gcttatgaaa
    22081 tgtatgttga ccgtatccaa aaacatatcg gtcagtacct tgcagtgcta aatggagcag
    22141 atgccattgt tttcacagca ggtgtcggtg aaaatgcaga gaatttccgt cgtgatgtaa
    22201 tctcagggat ttcgtggttt ggttgtgatg ttgatgatga aaagaatgtc tttggcgtta
    22261 caggagacat ctcaacagag gcagctaaaa tccgtgtctt ggttattcca acagatgaag
    22321 aattagtcat tgcccgtgac gttgaacgct tgaaaaaata agtgaaacta aaaaaatatt
    22381 caatacaagg agttgggaaa gttatttttc cagcttcttt ttctgatgaa attgtccaaa
    22441 accttgctat gattggcttt tttgaaaaat atggtataat agtagtaatt taatagatgg
    22501 agttgagttt tgaagaaaaa ctttcgtgta aaaagagaga aagattttaa ggcgattttc
    22561 aaggagggga caagttttgc taatcgcaaa tttgtggtct accaattaga aaaccagaaa
    22621 aaccattttc gagtaggtct atcagttagc aaaaaactgg ggaatgccgt cactagaaat
    22681 caaattaagc gacggattcg gcatattatc cagaatgcaa aagggagtct ggtagaagat
    22741 gtcgactttg ttgtcattgc tcgaaaagga gtcgaaacct tgggatacgc agagatggag
    22801 aaaaatctac tccatgtatt aaaattatca aagatttacc gggaaggaaa tgggagtgaa
    22861 aaagaaacta aagttaacta gtttgctagg actgtctctg ttaatcatga cagcctgtgc
    22921 gactaatggg gtaactagcg atattacagc cgaatcggct gatttttgga gtaaattggt
    22981 ttacttcttt gcggaaatca ttcgcttttt atcgtttgat attagtatcg gagtggggat
    23041 tattctcttt acggtcttga ttcgtacagt cctcttgcca gtctttcagg tgcaaatggt
    23101 ggcttctagg aaaatgcagg aagctcagcc acgcattaag gcgcttcgag aacaatatcc
    23161 aggtcgagat atggaaagca gaaccaaact agagcaggaa atgcgtaaag tatttaaaga
    23221 aatgggtgtc agacagtcag actctctttg gccgattttg attcagatgc cggttatttt
    23281 ggccctgttc caagccctat caagagttga ctttttaaag acaggtcatt tcttatggat
    23341 taaccttggt agtgtggata caacccttgt tcttccgatt ttagcagcag tattcacctt
    23401 tttaagtact tggttgtcca acaaagcttt gtctgagcga aatggcgcta cgactgcgat
    23461 gatgtatggg attccagtct tgatttttat ctttgcagtt tatgcgccag gtggagtcgc
    23521 cctatactgg acagtgtcta atgcttatca agtcttgcaa acctatttct tgaataatcc
    23581 attcaagatt atcgcagagc gcgaggccgt agtacaggca caaaaagatt tggaaaatag
    23641 aaaaagaaaa gccaagaaaa aggctcagaa aacgaaataa ataaggagga atctggtaat
    23701 ggtagtattt acaggttcaa ctgttgaaga agcaatccag aaaggattga aagaattaga
    23761 tattccaaga atgaaggctc atatcaaagt catttctagg gagaaaaaag gctttcttgg
    23821 tctatttggt aaaaaaccag cccaagtgga tattgaagcg attagtgaaa cgactgttgt
    23881 caaagcaaat caacaggtag taaaaggcgt tccgaaaaaa atcaatgatt tgaacgagcc
    23941 tgtgaagacg gttagtgaag aaaccgttga ccttggtcat gtggttaatg ctattaaaaa
    24001 aatagaggaa gaaggtcaag gtatttctga tgaagtcaag gctgaaatct taaaacatga
    24061 aagacatgcc agcactatct tagaagaaac tggtcacatt gagattttaa atgaacttca
    24121 aatcgaggaa gcgatgaggg aagaagcagg cgctgatgac cttgaaactg agcaagatca
    24181 aactgaaaat caagacttga aagagatggg cttgaaggtc gagcaaagtt atgatattgc
    24241 ccaggtggct acggatgtga ctgcctatgt tcaagcgatt gtggatgaca tggatgttga
    24301 ggctacactt tcaaatgatt ataaccgtcg tagcatcaat ctacaaattg acaccaacga
    24361 accaggtcgt attatcggct accatggtaa agtcttgaag gccttgcaac tgttggctca
    24421 aaattatctt tacaaccgct attccaaaac cttctacgtt acaatcaatg tcaatgatta
    24481 tgtcgaacac cgtgcagaag tcttgcagac ctatgcgcaa aaattggcga atcgtgtttt
    24541 ggaagaaggt cgcagtcata aaacagatcc aatgtcaaat agcgaacgca agattatcca
    24601 tcgtattatt tcacgtatgg atggcgtgac tagttactct gaaggtgatg agccaaatcg
    24661 ctatgttgtt gtagatacag aataagtaaa atcagggttg acctgatttt ttgctagtta
    24721 gaggaggtta aactgatgtt gaataagata agagactatc tagacttttc tggtttgcag
    24781 taccgtagtc ctgataaagc gggagcagag cgagagaaga tgctggcgtt ccgccacaaa
    24841 ggacaagagg cccgaaaggc ttttacagaa ctggccaaag cctttcaagc aagccatcca
    24901 gaatggcaac tccaacagac tagtcagtgg atgaatcagg cccagcgttt gagaccacat
    24961 ttttgggttt atctacagag agacggacaa gtgacagaac ctatgatggc cttacgtttg
    25021 tatgggacat ctactgactt tggaatttct ttggaagtca gtttcatcga acgtaagaag
    25081 gatgagcaaa cactgggcaa gcaggccaaa gttttagaca ttccaaccgt taaagggatt
    25141 tattatctaa cctactctaa tggtcaaagt caacggtggg aggcgaatga agaaaagcgt
    25201 cgtactttac gcgagaaggt gagaagtcaa gaagttcgaa aagttttagt gaaggtagat
    25261 gttcctatga cagaaaattc gtctgaagaa gaaatcgtag aaggcttatt gaagtcttat
    25321 tctaaaattc ttccctatta tctagctacg agaaaataag ataatttgta aaacatcata
    25381 aatcatacag tccaagagtg aacagtccgc tgtgtaattc ttggtctttt tgtttgcgct
    25441 ttcgcattat ataataaact tacaaaaaca attcaaaagg agaacaatta tggaagtcgt
    25501 ttcaagtgtt ctaaattggt tttctagcaa tattttgcag aatcccgcat ttttcgtagg
    25561 tttattggtg ttgataggat atgcactttt gaaaaaacct gcccatgacg ttttttcagg
    25621 gtttgttaaa gcaacagtag ggtatatgtt gcttaacgtg ggtgctggtg gtttggttac
    25681 aacctttcgt ccaatcttag cagctcttaa ctacaaattc caaattggtg cagcggttat
    25741 cgacccttat tttggacttg ctgcagcaaa caacaaaatt gtagcagagt ttccagattt
    25801 tgttggaact gcaactacag ctctattgat tggttttgga ataaatatct tgctcgtagc
    25861 tcttcgaaag attacgaagg taagaaccct ctttattact ggtcacatca tggtacaaca
    25921 agctgcaaca gtatctctta tggttctatt cttagtacca caattgcgca atgcttacgg
    25981 tacagcagcg attggtatca tctgtggact ttactgggca gttagttcaa atatgactgt
    26041 tgaggcaact caacgcttga ctggtggtgg cggatttgcg attggtcacc aacagcaatt
    26101 tgcaatctgg tttgtagata aagtagcagg acgctttggt aagaaagaag aaagtttaga
    26161 caatcttaaa ttacctaagt tcctctcaat cttccacgat acagttgttg catctgctac
    26221 cttgatgctc gtattcttcg gagccattct tttaatcttg ggtccagaca ttatgtctaa
    26281 taaagaagtc atcacttcag gaactctatt caatcctgct aaacaagatt tctttatgta
    26341 cattatccaa acagccttta ccttctcagt ttacttgttc gttttgatgc aaggtgtccg
    26401 aatgttcgta tctgagttga caaacgcctt ccaaggtatt tcaaacaaat tgttgccagg
    26461 ttcattccca gcggttgacg ttgcagcttc ttatggattt ggttctccaa atgctgtctt
    26521 gtcaggattt acctttggtt tgattggtca attgattaca attgtcttgc tcatcgtctt
    26581 taaaaatccg attcttatta ttacaggatt tgtaccagtg ttctttgaca atgcagccat
    26641 tgcggtctac gctgataaac gcggcggatg gaaagcggct gttatccttt cctttatatc
    26701 aggtgtcctt caagttgctc taggagctct ttgtgtggcc cttctcgatt tggcagctta
    26761 tggtggctac catggaaata tcgactttga attcccatgg cttggatttg gatatatctt
    26821 caaatacctt ggtattgttg gttatgtact tgtgtgtctc ttcttgcttg ttattcctca
    26881 acttcaattt gccaaagcaa aagataaaga gaaatattac aacggtgaag ttcaagaaga
    26941 agcttagtat ctagaaaagg agaaataaaa tggttaaagt attagcagcg tgcggaaatg
    27001 gaatgggttc atcaatggtt atcaagatga aggttgaaaa tgctctccgt aagcttaatc
    27061 aaagagattt tacagtcaat tcatgcagtg tcggtgaagc taaaggttta gcagtaggat
    27121 atgacatcgt aatcgcttct cttcatttga ttcaagaatt ggaagggcga actaatggga
    27181 agttaattgg gcttgataac ttgatggatg ataaagaaat caccgaaaaa ctcagtcaag
    27241 cactacagta aaaggttgga gggggctgga cagaaactga gagttatcgt ttctgtcctt
    27301 ctccctctta aataaaggag gcagatatga atttaaaaca agctttaatt gacaatgact
    27361 cgatccgact aggtttagag gctaacaatt ggaaagaagc agtcaaggta gcagtagatc
    27421 ccttaattga aagtggggca attttgccag agtattacga tgctatcatt gaatcgactg
    27481 aagagtatgg gccttactat atcttgatgc caggtatggc tatgccccac gctagacctg
    27541 aagctggtgt gcaaagtgat gccttttcat tgattacctt acaaaatcct gttgtatttt
    27601 cagatgggaa agaggtatct gttttgttgg cactagcagc aacaagctca aaaattcaca
    27661 caagtgtagc cattccacaa attattgccc tgtttgaatt agaagattct attgcacgtt
    27721 tacaggcttg ccagactaaa gaagatgtct tggctatgat tgaagaatct aaggatagcc
    27781 cttatctcga aggattggat ttggaaagtt agaaagagga ataaagaaat gacaaaaaga
    27841 atacctaatt tacaagttgc attagaccat tcagacttgc aaggagcgat taaagcagct
    27901 gtttctgttg gtcaggaagt agatattatc gaagctggaa ctgtttgctt gcttcaagtt
    27961 ggaagtgaac tggctgaagt cttgcgtagc cttttcccag ataagattat tgtggcagac
    28021 acaaaatgtg ctgatgctgg tggaacagtt gctaaaaata atgcggttcg tggagcagac
    28081 tggatgactt gtatctgttg tgcaaccatc cctactatgg aagcagctct aaaggctatc
    28141 aagactgaac gaggagaacg aggcgaaatc cagatcgagc tttatggcga ttggactttt
    28201 gaacaagctc agctttggct agatgcaggt atctcacaag ctatttatca ccaatctcgt
    28261 gatgctcttc ttgctggtga aacttggggt gaaaaagacc ttaataaggt taaaaaactc
    28321 attgacatgg gcttccgtgt atctgtaaca ggtggtctag atgtagatac tctcaaactc
    28381 tttgaaggtg ttgatgtctt tacctttatc gcaggtcgtg gaattacaga ggctgcggat
    28441 ccagcaggag cagcgcgtgc cttcaaggat gaaatcaaac gaatttgggg gtaaatcatg
    28501 gtacgtccaa ttggaattta tgaaaaggca accccaacac actttacttg gctagaacgt
    28561 ttaaattttg ccaaggagtt aggctttgat tttgtcgaga tgtctattga cgaacgtgac
    28621 gagcgtttag caagacttga ctggagtaag gaagaacgct tggaagttgt caaagcaatc
    28681 tatgaaactg gtgttcgtat tccttctatc tgtttttcag gccatcgtcg ctacccattg
    28741 ggttcaaaag atccagttct agaggaaaaa tctctagaac tcatgaaaaa atgtatcgaa
    28801 ttagctcaag acttgggagt tcgtacgatt caattagctg gttacgatgt ttactatgag
    28861 gaaaagtcac cccagacacg ccaacgtttt atcaaaaatt tgagaaaagc ctgtgactgg
    28921 gctgaagaag ctcaggtggt acttgctatt gaaattatgg atgatccttt catcagtagc
    28981 atcgaaaaat atttggctat agaaaaagag attgactctc ccttcctctt tgtatatcca
    29041 gatattggta atgtgtctgc atggcataat gatatctata gtgagtttta tcttggtcat
    29101 catgccatcg cagctctcca tctcaaggat acttatgcag tgacagaaag ttcaaggggc
    29161 cagttccgag atgtaccttt tgggcaaggt tgtgtcaaat gggaagaagc tttcgatatt
    29221 ttaaaggaaa ccaattataa tggacctttc ctaatcgaaa tgtggtctga aaattgtgaa
    29281 acagtagaag aaacacgcgc agccattcaa gaggcgcaag cttttctcta tccactcatt
    29341 aagaaagcag gtttgatgta agatgaatca agtaatcaat gctatgcgta aacgagtctg
    29401 tgatgccaat caatcattgc caaaacatgg acttgtcaaa tttacctggg ggaatgtatc
    29461 tgaagtcaat cgcgaactcg gtgtcattgt tatcaaacca tcaggcgtgg attatgacga
    29521 attgacacct gaaaacatgg tagtgactga tctagatggt aagatcctag aaggggattt
    29581 aagaccatct tccgacctcc caactcatgt gcaattatat agggcttggt cagaaattgg
    29641 tagtgtggtt cacacccatt cgacagaagc tgttggttgg gctcaggcag gtcgtgatat
    29701 tcctttctac ggaacaaccc atgcagatta tttctacggt tcaatccctt gcgcccgtag
    29761 tttgaccaag gacgaagtag aagtggccta tgaaaaagat actggcctgg ttatcgtaga
    29821 agaatttgaa catcgcggac ttaacccggt tgaagtacca ggaattgttg tacgcaatca
    29881 cggtccattc acctggggca aaaatccaga gaatgctgtt tatcactctg tcgtactaga
    29941 ggaagtatca aagatgaatc gctttacaga acaaatcaat ccaagagttg gacctgctcc
    30001 ccagtacata ctagaaaaac actaccaacg taaacatgga ccaaatgctt attatggtca
    30061 aaagtaagaa cgatgaagga ggagaaaaag ataaatttag ctcctctttt tacatttgat
    30121 ttttattgag agtaaagttg gagttgaagt aattttgaaa gattttttag aaatagcgct
    30181 tgatatatat atggtaaaat aaaaagaatt gctgtgatat caatagattt gggggatttt
    30241 ttaatatggt actggataag gcaagttgtg atttacttca atatttgatg gatcaagaaa
    30301 cgtccaaaac gattatggcg atttcgaaag atttgaaaga gtcaagaagg aaaatttatt
    30361 atcacattga caaaatcaat gctgctctgg gtgacgaggc gcttcacatc attagtattc
    30421 cacgaattgg tattcactta acggaagagc agagagatgc ttgttgtaaa ctattatcgg
    30481 aagtagattc gtacgattat atcatgagtg cacatgaacg tatgatgata atgttactat
    30541 ggataggtat ttctaaagaa cgtattacga ttgaaaaatt gatagagtta acagaggtat
    30601 ctaggaatac tgttctcaat gatttgaata gtattcgtta tcaactaact ttggaacaat
    30661 atcaggtgat cttgcaagtg agcaagtcac agggatacca ccttcatgcc caccctctta
    30721 ataaaattca gtatcttcaa tcgcttctat atcatatttt tatggaagaa aatgccactt
    30781 ttgtatctat tttagaagat aagatgaaag agaggttaga tgatgagtgt ttgctttctg
    30841 ttgaaatgaa ccaatttttt aaggaacagg ttcctttagt tgaacaagat ttagggaaga
    30901 aaataaacca tcatgaaata acttttatgt tgcaggttct accttatttg ctgttaagct
    30961 gtcataatgt tgaacagtat caagaaagac atcaggatat agagcaagaa ttttctttga
    31021 taagaaaaag aatagagtat caggtgtcta agaagttagg agaacggttg tttcaaaagt
    31081 ttgaaatttc tttgtcagga cttgaagttt ctcttgtagc tgttctcctc ctctcctatc
    31141 gtaaagattt ggatattcat gcagaaagtg atgattttcg gcaattaaaa cttgctttag
    31201 aagaatttat ctggtatttt gaatcacaaa tccgaatgga gattgagaac aaggatgatt
    31261 tgttacgaaa tttgatgatc cactgtaaag ccttgttatt tagaaagact tacggtattt
    31321 tttctaaaaa tcctctaaca aaacaaattc gatccaagta tggagaatta tttttagtca
    31381 ctagaaaatc tgcggaaatt ttagaaggag catggtttat tcggctaaca gacgatgata
    31441 ttgcctattt gacgattcat attggaggat ttttaaaata tacaccatcg tctcaaaaaa
    31501 atatgaaaaa agtttatctc gtttgtgatg aaggtgttgc ggtttcgaga cttttgctga
    31561 aacaatgcaa actttatttt ccaaatgagc aaattgacac tgtatttaca acagaacaat
    31621 ttaagagtgt ggaagatatt gcacaagttg atgtagtgat tactactaat gatgatttgg
    31681 atagcagatt tccgatttta agggttaatc ctatccttga agcagaagat attttgaaaa
    31741 tgctagacta tcttaaacac aatatatttc gtaataagag caaaagtttc agtgaaaatc
    31801 tttctagtct tatttcgtct tatattgtag acagcaagtt ggctagtaag ttccaagaag
    31861 aggttcaaac acttataaat caagaaatag tagttcaagc ttttttggaa gatatttgaa
    31921 ggacagtcca atgatgaaca caaacctgtg tttttcttgg tcttttttag tgttttgaag
    31981 ggtggtatac taatctcaaa gataacaatt atatccaaag gaggcaacat atgccaaacg
    32041 tcaaagaaat tacaagagag tcatggattt tagccacttt cccagagtgg ggaacatggt
    32101 tgaacgaaga aatcgaagaa gaagtcgtac ctgaaggcaa ctttgccatg tggtggctag
    32161 gcaactgtgg tacttggatt aagacaccag ctggtgctaa cgttgtcatg gacctttggt
    32221 caaaccgtgg aaaatcaacc aaaaaagtga aagatatggt tcgtgggcac caaatggcaa
    32281 atatggcagg tgttcgtaag ttgcaaccaa acttgcgtgt tcagccaatg gttatcgatc
    32341 catttgctat caacgaacta gactattact tagtttcaca cttccacagt gatcatatcg
    32401 acccatacac agctgcagca attctcaaca atcctaagtt agagcatgtt aagtttatcg
    32461 gtccttacca ctgtggacga atctgggaag gatggggtgt tccaaaagaa cgtatcatcg
    32521 ttgttaaacc aggtgacact atcgaattaa aagatatgaa gattcatgca gtagaatcat
    32581 ttgaccgtac ttgcttggta actctcccag tgaacggtgc tgatgagaca ggcggtgaac
    32641 ttgctggctt ggctgttaca gatgaagaaa tggctcaaaa ggctgttaac tatatctttg
    32701 aaacaccagg tggaaccatc tatcatggtg cagattctca cttctcaaac tattttgcaa
    32761 aacatggtaa agactttaaa attgatgttg ctttgaataa ctatggtgaa aatccggtag
    32821 gtatccaaga caaaatgaca tctatcgacc ttcttcgtat ggcagaaaat ctgcgtacca
    32881 aagtcattat cccagttcac tatgatatct ggtctaactt catggcttct actaatgaga
    32941 ttctagaact ttggaaaatg cgaaaagatc gcttgcaata cgatttccat ccatttatct
    33001 gggaagttgg cggtaagtac acttatcctc aagatcaaca cttagtagaa taccatcatc
    33061 cacgtggttt tgatgattgt tttgaacaag actctaacat tcaatttaaa gctttgctat
    33121 aatataaaaa tattctttgg aggttatccg tatgttgcat gatacggata attttcatat
    33181 aatagtaaaa tagaatgtgt gattcaataa tcacctcaaa tagaaaggaa attctatgtc
    33241 aaatctatct gttaatgcaa ttcgttttct aggtattgac gccattaata aagccaactc
    33301 aggtcatcca ggtgtggtta tgggagcggc tccgatggct tacagcctct ttacaaaaca
    33361 acttcatatc aatccagctc aaccaaactg gattaaccgc gaccgcttta ttctttcagc
    33421 aggtcatggt tcaatgctcc tttatgctct tcttcacctt tccggttttg aagatgtcag
    33481 catggatgag attaagagtt tccgtcaatg gggttcaaaa acaccaggtc acccagaatt
    33541 tggtcatacg gcagggattg atgctacgac aggtcctcta gggcaaggga tttcaactgc
    33601 tactggtttt gcccaagcag aacgtttctt ggcagccaaa tataaccgtg aaggctacaa
    33661 tatctttgac cactatactt acgttatctg tggagacgga gacttgatgg aaggtgtctc
    33721 aagcgaggca gcttcatacg caggtttgca aaaacttgat aagttggttg ttctttatga
    33781 ttcaaatgat atcaacttgg atggtgagac aaaggattcc tttacagaaa gtgttcgtga
    33841 ccgttacaat gcctacggtt ggcatactgc cttggttgaa aatggaacag acttggaagc
    33901 catccatgct gctatcgaaa cagcaaaagc ttcaggcaag ccatctttga ttgaagtgaa
    33961 gacggttatt ggatacggtt ctccaaacaa acaaggaact aatgctgtac acggcgcccc
    34021 tcttggagca gatgaaactg catcaactcg tcaagccctc ggttgggact acgaaccatt
    34081 tgaaattcca gaacaagtat atgctgattt caaagaacat gttgcagacc gtggcgcatc
    34141 agcttatcaa gcttggacta aattagttgc agattataaa gaagctcatc cagaactggc
    34201 tgcagaagta gaagccatca tcgacggacg tgatccagtc gaagtgactc cagcagactt
    34261 cccagcttta gaaaatggtt tttctcaagc aactcgtaat tcaagtcaag atgccttgaa
    34321 tgttgtggca gctaaattac caaccttcct aggtggatca gctgaccttg ctcactcaaa
    34381 catgacttat atcaagacgg atggacttca agacgatgcc aatcgcttga atcgtaacat
    34441 tcagtttggt gttcgtgaat ttgcaatggg aacaatcttg aacgggatgg cccttcatgg
    34501 tggacttcgt gtatacggtg gaactttctt cgtcttctct gactatgtga aggcagctgt
    34561 ccgcttgtca gccttacaag gacttcctgt gacttatgtc tttacccatg attcaatcgc
    34621 agttggggaa gatggtccga ctcacgaacc agttgagcat ttagcaggtc ttcgtgctat
    34681 gccaaatcta aatgttttcc gtccagcaga tgcgcgtgaa acgcaagcag cttggtacct
    34741 tgcagtgaca agtgagaaaa caccaactgc ccttgtcttg acacgtcaaa acttgactgt
    34801 tgaagatgga acagacttcg acaaggttgc taaaggtgct tatgttgtat atgaaaatgc
    34861 agccgacttt gataccatct tgattgcgac aggttcagag gttaatcttg ctgtctcagc
    34921 tgctaaagaa ttggctagtc aaggcgaaaa aatccgcgta gtcagcatgc catctacaga
    34981 tgtctttgat aaacaagatg cagcttacaa ggaagaaatt cttccaaatg cagtccgccg
    35041 tcgtgttgca gtcgaaatgg gtgcaagtca aaactggtac aaatatgttg gtctcgatgg
    35101 tgccgttcta ggtattgata ccttcggagc ctctgcccca gcaccaaaag tattggcaga
    35161 atatggcttt actgtcgaaa atcttgtaaa agttgttcga aatttgaaat aatcctaaaa
    35221 atcagggcgt aagctctggt ttttcttacc agaaaagtaa ggtacaatct tgtaaaagaa
    35281 gctgaaattt gatatagtag tcctatgtaa aagacaaagg agaaaacaat gaatccaaat
    35341 attacttttt taatcatgct tgtaggtatg atggccttga tgttctttat gcaacgttct
    35401 caaaagaaac aagctcaaaa gcgtatggaa agcttaaata aactacaaaa aggctatgaa
    35461 gtgattacaa tcggtggact ttatggaaca gtcgatgaag tagatacgga gaagggaaca
    35521 atagttcttg acgtagatgg agtttacttg acttttgaac tagctgctat caagacagta
    35581 ttaccgctga aagaaacagc ttcactagaa ggcgcaattg aaaaataaga cgggatcacg
    35641 aactcccgtt ttctataaaa gaaaggaaat gggatgaaaa aattagtctt tgtctgtctg
    35701 ggaaatattt gccgtagccc tatggccgag tttgttatga aatcaatgac agataactac
    35761 gaaatccaaa gtcgagcaac ttcctcttgg gaacatggca atccgattca taaggggact
    35821 cagggaattt ttcaagagta tgagattcct tatgacaaga acaagacatc gcttcagatt
    35881 agtaaggaag attttgaagc ctttgattat attatcggaa tggacgcttc aaatgtttcc
    35941 gacttacgtc agatgtgtcc agtagactgt caagataaga tttactcatt ttcatctgaa
    36001 agtgttccag acccttggta tacaggagat tttgaagaaa cctatcgacg tgttcaagag
    36061 ggctgtcaag cttggttaga acgtttagaa aaggagagtt aaggtggaaa atcttacgaa
    36121 tttttacgaa aagtatcgtg tttatctgac tcgtccacgt ttagagattt tgacagtagt
    36181 taccattgtt ttctgtgctg tactcgtctt ttttctaaat attccaggaa aaggtgtctt
    36241 aaaactcgat aatggaacga ttgtttatga tggcagtctt gtccgcggta aaatgaatgg
    36301 ccaaggtacc attaccttcc aaaatggaga ccaatataca ggtggcttca acaatggagc
    36361 cttcaacgga aaaggtacct ttcaatctaa agaaggctgg acctacgaag gtgattttgt
    36421 aaatggtcag gctgaaggaa aagggaaact aacaacagaa caagaagtcg tttatgaagg
    36481 aacttttaaa caaggcgttt ttcaacaaaa ataaagcctc cttatcaaag gaggtattat
    36541 tagaattaca aggtaagcgc ttacctgtaa atccctttct ttccaaatcc ctcttccaag
    36601 caagtttgtg aaataaaaaa tatttgaaat aaatttcaca aactttaaag ataaaacctg
    36661 ataagaaaag aaaatgagaa aagtttcaca agagtttaaa aattctttgt gaaatgttta
    36721 tgaaactgtt tacaaagttg aaataatgcg ttataataaa cttgtgaaaa aattaacaaa
    36781 ggatatcgat ccttgaaagc tatggaggaa aatatggctg ataaaaaaac tgtgacacca
    36841 gaggaaaaga aactcgttgc tgaaaaacac gtagatgagt tggttcaaaa agctctagtt
    36901 gcccttgaag aaatgcgtaa attggatcaa gagcaagttg actacatcgt tgccaaagca
    36961 tcagtagcag ctttggatgc ccacggagaa ttggctttac atgcctttga agaaacagga
    37021 cgtggtgtat ttgaagataa agcaactaag aacttgtttg cttgtgaaca cgtagtaaac
    37081 aacatgcgcc acactaagac agttggcgtt atcgaagaag acgatgtaac aggattgact
    37141 cttattgctg aaccagttgg tgttgtttgt ggtattactc caacaacaaa cccaacatca
    37201 acagcaatct tcaaatcatt gatttcattg aagacacgta acccaatcgt ctttgccttc
    37261 catccatcag cacaagaatc atctgctcat gcagctcgta tcgtccgcga tgcagctatc
    37321 gcagctggtg ctcctgaaaa ctgtgtgcaa tggattactc aaccatctat ggaagcaaca
    37381 agtgccctta tgaaccacga aggtgttgcg acaatccttg caacaggtgg taatgccatg
    37441 gttaaggcgg cttattcatg tggtaaacca gctcttgggg taggtgccgg aaacgttcca
    37501 gcttatgttg aaaaatcagc aaacattcgt caagcagcac acgatatcgt catgtctaaa
    37561 tcatttgata acggtatggt ctgtgcatct gaacaagcag ttatcattga taaagaaatt
    37621 tacgatgaat ttgtagcaga gttcaaatct taccacactt actttgtaaa caaaaaagaa
    37681 aaagctcttc ttgaagagtt ctgcttcggc gtcaaagcaa acagcaaaaa ctgtgctggt
    37741 gcaaaattga acgctgacat cgttggtaaa ccagcaactt ggattgcaga acaagcagga
    37801 tttacagttc cagaaggaac aaacattctt gctgcagaat gtaaagaagt tggcgaaaat
    37861 gagccattga ctcgtgaaaa attgtcacca gttattgcag ttttgaaatc tgaaagccgt
    37921 gaagatggta ttactaaggc tcgtcaaatg gttgaattta acggtcttgg acactcagca
    37981 gctatccaca cagctgacga agaattgact aaagaatttg gtaaagctgt taaagctatt
    38041 cgtgttatct gtaactcacc ttctactttt ggtggtatcg gggacgttta caatgccttc
    38101 ttgccatcat tgacacttgg atgtggttct tacggacgca actcagttgg ggataacgtt
    38161 agtgccatta acctcttgaa tatcaaaaaa gtcggaagac ggagaaataa catgcaatgg
    38221 atgaaacttc cttcaaaaac atactttgaa cgtgattcaa ttcaatacct tcaaaaatgt
    38281 cgtgacgttg aacgtgtcat gatcgttact gaccatgcca tggtagagct tggtttcctt
    38341 gatcgtatca tcgaacaact ggaccttcgt cgcaataagg ttgtttacca aatctttgcg
    38401 gatgtagaac cggatccaga tatcacaact gtaaaccgtg gtactgagat tatgcgtgcc
    38461 ttcaaaccag ataccatcat cgcactcggt ggtgggtctc caatggatgc tgccaaagta
    38521 atgtggctct tctacgagca accagaagtg gacttccgtg accttgtcca aaaattcatg
    38581 gatatccgta aacgtgcctt caagttccca ttgcttggta agaagactaa attcatcgcg
    38641 attccaacta catctggtac aggatctgaa gtaacaccat ttgccgttat ctctgataaa
    38701 gcaaacaacc gtaaataccc aatcgctgac tactcattga caccaactgt ggcaatcgta
    38761 gatcctgctt tggtattgac agttccagga tttgttgctg ctgatactgg tatggacgta
    38821 ttgactcacg cgacagaagc atacgtatca caaatggcta gtgactacac tgatggttta
    38881 gcacttcaag ccattaaatt ggtctttgaa aatctcgaaa gctcagttaa gaatgcagac
    38941 ttccactcac gtgagaaaat gcataacgct tcaacaatcg ctggtatggc ctttgccaat
    39001 gccttcctag gtatttctca ctcaatggcc cataagattg gtgcgcaatt ccacacaatc
    39061 cacggtcgta caaatgctat cttgcttcca tacgttatcc gttacaacgg tacacgtcca
    39121 gctaagacag caacatggcc taagtacaac tactaccgtg cagatgaaaa ataccaagat
    39181 atcgcacgca tgcttggact tccagcttct actccagaag aaggggttga atcttacgca
    39241 aaagctgtct acgaactcgg tgaacgtatt gggatccaaa tgaattttag agaccaagga
    39301 attgacgaaa aagaatggaa agaacattct cgtgaattag ccttcctggc ttatgaagac
    39361 caatgttcac cagctaaccc acgtcttcca atggtagacc atatgcaaga aatcatcgaa
    39421 gatgcatact atggctacaa agaaagacca ggacgccgta aataattgtt tatcagtcta
    39481 gaagcaagac aaaaactcaa tttgagggaa agatccagta atttttctat gataaaaggc
    39541 atcctatcaa ggtttttgaa cacctgatag gatgcctttt tatgatattg aggccttttt
    39601 gccctttttg aaaaactaga atagaaacaa aatatataat agattgaaac tggaatagta
    39661 cacttctgct tctaaaacat tgttagaatt cgatttgact gtcctgatcg atttgtccta
    39721 ttcctatttc attttattat ataaaaaata tagtatagta gactgaatct aaaatagtac
    39781 gaaacaa
//
LOCUS       DAVMJI010000020        37411 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.020, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000020 DAVMJI010000000
VERSION     DAVMJI010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.020"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            90..887
                     /locus_tag="VYR58_001205"
     CDS             90..887
                     /locus_tag="VYR58_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV3622366.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1035..2294
                     /locus_tag="VYR58_001206"
                     /pseudo
     CDS             1035..2294
                     /locus_tag="VYR58_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2390..3664
                     /locus_tag="VYR58_001207"
     CDS             2390..3664
                     /locus_tag="VYR58_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV3622367.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3674..4552
                     /gene="truB"
                     /locus_tag="VYR58_001208"
     CDS             3674..4552
                     /gene="truB"
                     /locus_tag="VYR58_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV3622368.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSLLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4813..5115
                     /locus_tag="VYR58_001209"
     CDS             4813..5115
                     /locus_tag="VYR58_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV3622369.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5223..5861
                     /gene="udk"
                     /locus_tag="VYR58_001210"
     CDS             5223..5861
                     /gene="udk"
                     /locus_tag="VYR58_001210"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV3622370.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5989..7329
                     /locus_tag="VYR58_001211"
     CDS             5989..7329
                     /locus_tag="VYR58_001211"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV3622371.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEKGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7307..7519
                     /locus_tag="VYR58_001212"
     CDS             7307..7519
                     /locus_tag="VYR58_001212"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV3622372.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7516..8391
                     /locus_tag="VYR58_001213"
     CDS             7516..8391
                     /locus_tag="VYR58_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV3622373.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQIIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8384..9199
                     /locus_tag="VYR58_001214"
     CDS             8384..9199
                     /locus_tag="VYR58_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV3622374.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQIFAEIKEAVERAHSQFKNE"
     gene            9192..9623
                     /locus_tag="VYR58_001215"
     CDS             9192..9623
                     /locus_tag="VYR58_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV3622375.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9630..11297
                     /gene="recN"
                     /locus_tag="VYR58_001216"
     CDS             9630..11297
                     /gene="recN"
                     /locus_tag="VYR58_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV3622376.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11299..12027
                     /locus_tag="VYR58_001217"
     CDS             11299..12027
                     /locus_tag="VYR58_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV3622377.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12106..13929
                     /gene="lepA"
                     /locus_tag="VYR58_001218"
     CDS             12106..13929
                     /gene="lepA"
                     /locus_tag="VYR58_001218"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV3622378.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14088..14168)
                     /locus_tag="VYR58_001219"
                     /pseudo
     CDS             complement(14088..14168)
                     /locus_tag="VYR58_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14342..14817
                     /locus_tag="VYR58_001220"
                     /pseudo
     CDS             14342..14817
                     /locus_tag="VYR58_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            14855..15157
                     /locus_tag="VYR58_001221"
     CDS             14855..15157
                     /locus_tag="VYR58_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV3622379.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            15165..15966
                     /locus_tag="VYR58_001222"
                     /pseudo
     CDS             15165..15966
                     /locus_tag="VYR58_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            16015..16473
                     /locus_tag="VYR58_001223"
                     /pseudo
     CDS             16015..16473
                     /locus_tag="VYR58_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
     gene            complement(16495..17448)
                     /locus_tag="VYR58_001224"
     CDS             complement(16495..17448)
                     /locus_tag="VYR58_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV3622380.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HTEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            17882..18307
                     /gene="lacA"
                     /locus_tag="VYR58_001225"
     CDS             17882..18307
                     /gene="lacA"
                     /locus_tag="VYR58_001225"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV3622381.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            18338..18853
                     /gene="lacB"
                     /locus_tag="VYR58_001226"
     CDS             18338..18853
                     /gene="lacB"
                     /locus_tag="VYR58_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV3622382.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQIDANFFTEF
                     LEKWDRGEYHD"
     gene            18864..19793
                     /locus_tag="VYR58_001227"
     CDS             18864..19793
                     /locus_tag="VYR58_001227"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV3622383.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            19795..20775
                     /gene="lacD"
                     /locus_tag="VYR58_001228"
     CDS             19795..20775
                     /gene="lacD"
                     /locus_tag="VYR58_001228"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV3622384.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            21009..21845
                     /locus_tag="VYR58_001229"
     CDS             21009..21845
                     /locus_tag="VYR58_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV3622385.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            21881..22198
                     /locus_tag="VYR58_001230"
     CDS             21881..22198
                     /locus_tag="VYR58_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV3622386.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            22200..23894
                     /locus_tag="VYR58_001231"
     CDS             22200..23894
                     /locus_tag="VYR58_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV3622387.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            24109..25515
                     /gene="lacG"
                     /locus_tag="VYR58_001232"
     CDS             24109..25515
                     /gene="lacG"
                     /locus_tag="VYR58_001232"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV3622388.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDAPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            25605..25817
                     /locus_tag="VYR58_001233"
     CDS             25605..25817
                     /locus_tag="VYR58_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV3622389.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(26096..26857)
                     /locus_tag="VYR58_001234"
     CDS             complement(26096..26857)
                     /locus_tag="VYR58_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV3622390.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(27145..28107)
                     /gene="nrdF"
                     /locus_tag="VYR58_001235"
     CDS             complement(27145..28107)
                     /gene="nrdF"
                     /locus_tag="VYR58_001235"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV3622391.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(28295..30454)
                     /gene="nrdE"
                     /locus_tag="VYR58_001236"
     CDS             complement(28295..30454)
                     /gene="nrdE"
                     /locus_tag="VYR58_001236"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV3622392.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDEEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(30535..30753)
                     /gene="nrdH"
                     /locus_tag="VYR58_001237"
     CDS             complement(30535..30753)
                     /gene="nrdH"
                     /locus_tag="VYR58_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV3622393.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            31104..31367
                     /locus_tag="VYR58_001238"
     CDS             31104..31367
                     /locus_tag="VYR58_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV3622394.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            31373..33106
                     /gene="ptsP"
                     /locus_tag="VYR58_001239"
     CDS             31373..33106
                     /gene="ptsP"
                     /locus_tag="VYR58_001239"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV3622395.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            33361..35811
                     /gene="phtA"
                     /locus_tag="VYR58_001240"
     CDS             33361..35811
                     /gene="phtA"
                     /locus_tag="VYR58_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV3622396.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            35969..>37411
                     /gene="phtB"
                     /locus_tag="VYR58_001241"
     CDS             35969..>37411
                     /gene="phtB"
                     /locus_tag="VYR58_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV3622397.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPSNPIDEKLVKEAVRKVGDGYV
                     FEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDL
                     LARIHQDLLDNKGRQVDFEALDNLLERLKDV"
BASE COUNT        11603 a         6756 c         8122 g        10930 t
ORIGIN      
        1 actataaact tttatgaaat acagaaaacg cttcctaaaa cctaaagttt gtgatataat
       61 tatcaagaaa aaagatttag gagtttatta tgatttcttc agaatttatc tcaaagattg
      121 aatttgcttg caataagaaa gaaagtcttt atagtcaaag caaatttaag tatgcgattc
      181 gttcgatgtt cgcaggtgca tttttaacct tcagtactgc tgcaggtgca gttggggctg
      241 acttgattaa taaaattgca ccaggtagtg gacgcttcct ctttccattc gtttttgctt
      301 ggggcttggc ctacattgtt tttttgaatg ccgagttggt cacttcaaac atgatgttct
      361 tgactgctgg tagtttctta aaaaaaatct cttggagaaa aacagctgag attttactat
      421 actgtacctt gttcaacctt atcggagcct tgatagcagg gtggggcttt gctcattcgg
      481 cagcctatgc gaatctgaca cacgatagtt tcatctcagg tgttgttgag atgaagttag
      541 gccgctcaaa tgaattggtc ttgcttgagg cgattttggc aaatattttc gtaaatattg
      601 cgattctgtc atttattttg gtcaaagatg gtggtgccaa actttggctt gtgttgtcag
      661 ctatttacat gtttgtattc ttaacaaacg agcacattgc ggcgaacttt gcttctttcg
      721 cgattgtgaa attcagtgtt gctgcggatt caattgccaa cttcggtgtt ggaaatatgc
      781 ttcgccactg gggtgtgact ttcatcggaa actttatcgg aggaggcctc ttgatgggtc
      841 ttccatatgc cttcctcaat aaaaacgaag atacttatgt agattaagaa aatgagcacg
      901 attgagtcgt gcttttttca ttttcaaaat aaggtaatag ctatttctta tatcaaaata
      961 tagaaaactg atatttgtaa actataactc aaggtgctac aatatcctta ataaaatgat
     1021 atggaggtca ccttatgact tgtgatttta aatctgaaac tctacaacta catgctggtc
     1081 aagttgtggc tccagctact aagtctcgtg cagtgccgat ttatcaaaca acattttttg
     1141 tttttgatga cacgtaggaa ggtgccgatc tgtttgcctt gaggaaacca gggaacattt
     1201 atactcgtat caccaatcct acaacagctg cccttgaagg tggtgttgaa gcgctagcaa
     1261 cagcatcagg tatgactgca gtgacttata cgattttggc gcttgcccat gctggtgacc
     1321 atgtagtggc tgcttcgact atttacggtg gaaccttcaa tcttttgaaa gaaccccttc
     1381 ctcgttatgg tatcacaaca acctttgtcg atgttgataa tttggaggaa gtagaagcag
     1441 ctatcaaaga caataccaag cttgtcttga ttgaaacctt gggtaacccc ttgattaata
     1501 ttccagacct ggaaaaactg gcagagattg ctcataaaca tcaaatccca cttgtgtcag
     1561 acaatacttt tgcaatacct tatttgatta acgtcttctc tcatggcgtt gacattgcca
     1621 ttcactctgc gactaagttt atcggtgggc atggtacaac tattggagga ataattgtcg
     1681 atagtggtcg ttttgactgg acggcttcag ggaaattccc tcaatttgtt gacgagggtt
     1741 caagctgcca caatttgagc tatattcgtg atgtgggtgc agcaaccttt attatagctg
     1801 ttcgagttca attgcttcgt gatacaggtg cagtcttgtc accattcaat gctttcctct
     1861 tgctacaaag acttgaaact ctttcacttc gtgtggaacg ccatgtacaa aatgctgaga
     1921 caattgttga ttttcttgtc aaccatccta aggtagaaaa ggtaaattat ccaaaacttg
     1981 cagatagtcc ttatcatgcc ttggctgaga aatacttgcc aaaaggtgtc ggttcaatct
     2041 ttaccttcca cgtcaaaggt gacgaggaag aagcacgcaa ggtcattgat aatttagaaa
     2101 tcttttctga ccttgcaaac gcggcagatg ctaaatcgct tgttgtccat ccagcaacaa
     2161 ccactcacgg tcaattgtca gaaaaagacc tagaagcagc aggtgtcaca ccaaaccaaa
     2221 ttcgtctgtc aatcggtctt gaaaatgtag aagatttgat tgaagactta cgcttggcct
     2281 tggaaaaaat ttaaagtaaa agaagataaa cagtgggttt tgactcactg tttttgattt
     2341 tccctcaggc atgatataat ggttacagaa gtctagaaag aggaatgtaa tgaacgaaat
     2401 caaatgtccc aactgtgggg aagtctttac agtaaatgaa agccagtatg ctgaactttt
     2461 gtcccaagtg agaacggcag agtttgataa ggaactacac gataggatga ggcaggaact
     2521 ggccttggct gagcaaaagg ctatgaatga gcaacagact aaactggctc agaaggatca
     2581 agaaattgcg caattgcaga gtcaaatcca aaactttgat acagaaaaag aattggccaa
     2641 gaaagaagtt gaacagacaa gccatcaggc cttattggct aaggacaagg aagtacaggc
     2701 tttggagaac caattggcca ctttgcgttt ggagcatgaa aatcaactgc aaaagaccct
     2761 ttctgaccta gaaaaagaac gcaatcaggt caaaaatcag ctcctactgc aagaaaagga
     2821 aaatgagttg tctttggctt ctgttaagca aaactacgaa gcccagctca aagcagccag
     2881 tgaacaagtc gagttttata agaattttaa ggctcaacaa tctacaaaag cgattgggga
     2941 aagcctagaa cagtatgcag agagtgagtt taacaaggtc cgtagtttcg cctttccaaa
     3001 tgcttacttt gagaaggata acaaggtctc ttcgcgtggg tctaaagggg actttatctt
     3061 ccgtgagtgt gatgaaaatg gagttgaaat catttctatc atgtttgaga tgaaaaacga
     3121 agcggacgga acagagaaga agcacaagaa tgcagatttt tacaaggaat tggacaagga
     3181 ccgtcgggag aagaactgtg agtatgccgt tttggtgacc atgcttgagg ccgataatga
     3241 ctactttaac acagggattg ttgacgtcag ccacgagtat gaaaaaatgt atgttgttcg
     3301 tcctcaattc tttatccagt tgattggtct cttacgtaat gcggcgctaa attccctaaa
     3361 atacaagcag gagttggcct tggttcgcga gcaaaatatt gacattacgc attttgagga
     3421 agatttggat gcctttaagc tagcttttgc taagaactat aattcagctt cgactaactt
     3481 tggaaaagct attgatgaaa tcgacaaggc catcaaacgc atggaagagg ttaagaaatt
     3541 cctgactaca tctgaaaacc aactccgtct agctaacaac aaattggaag atgtctctgt
     3601 taaaaaattg acccggaaaa atccaacaat gaaagcgaag ttcgaagcac tgaaggggga
     3661 gtagaaagca aaaatgaacg gtattattaa cttaaaaaag gaagcaggaa tgacctcgca
     3721 tgatgcggtt tttaaactgc gtaagatttt gggaaccaag aaaattggtc atggtggaac
     3781 cttggatccg gatgtggtgg gtgttttgcc gattgcggtt ggcaaggcga cacgcatggt
     3841 cgagtttatg caggacgagg gtaagatcta tgagggggaa atcactctgg gctattccac
     3901 gacgactgag gatgctagtg gggaagtggt cgcagaaacc cctgttttgt ctctcttgga
     3961 tgaaaagctt gttgatgaag cgattgctag cttgactggg cctattactc agattccccc
     4021 tatgtattcg gcagttaagg ttaatggtcg caagctctat gagtatgcgc gtgctggtca
     4081 ggaagtggag cgtccagaac gtcaggtgac catttatcaa tttgagcgaa caagtccgat
     4141 ttcttatgat ggccaacttg cccgattcac ttttcgtgta aaatgcagta aagggacgta
     4201 catccgtact ttgtcagttg atttgggtga aaagcttggt tatgcggctc atatgtccca
     4261 tttgactcgt actagtgctg ctggcttaca attagaagac gctcttgcct tggaggaaat
     4321 tgctgaaaaa gtagaggctg ggcaattaga ttttctccat cctttagaga ttgggacagg
     4381 tgaccttgtc aaagttttcc taactccaga agaggctaca gaagttcgct ttggtcgttt
     4441 tattgagcta gaccaaacgg acaaagaatt ggctgccttt gaagatgata aattgttagc
     4501 cattctagaa aaacggggca atctctataa gccaaggaag gtttttagct agatcgttta
     4561 ggaataaaaa tcgggtgata gataataatt gcttgataaa accccatact aatagtagaa
     4621 tggttttggg aattataata ttccaattgt tgcgagttgt aggtactcaa ataatctatt
     4681 aggtactcaa ataatctata tagaaattta gaggtgtgaa atgaagcaat ttaaaattct
     4741 ttcagataaa tatttagagt ccattacagg ttctggtggg aacttaggcc caggatttgg
     4801 tgtgataatt ccatgatgcg aaatgagttt cgagaaaggg tggagcaact tcttcaacaa
     4861 aaagaaataa atgaaaatag tgagttgagt cacctgtttc gtcttgctat acaaaattta
     4921 gacagaaatg aaaaatacca aacggtcatg gccaatttga gtcaagggtt gtcactttac
     4981 ctcatgacgc atcattacca ggcacctaag tctgtcattg attttggttt atggattgcc
     5041 aaagctccta gccaggaaag agggagactg gctttcttgc agatgcttgc tcaaacccta
     5101 cagggctttc gttaaaactg tcgaacatca gagggaagac tctggtgttt tttgctgatg
     5161 agactataaa ttttgtaaaa aatgtgatag aatagacgac ggataaaata acggaggata
     5221 gcatgcaaaa tagaccaatc attattggag tgacaggtgg ttctggtggt ggtaaaacta
     5281 gtgtttcaag agccatttta tcgcattttc ctgatgaaaa gatttccatg attgagcatg
     5341 attcatacta caaggatcag tctcatttga cctttgaaga gcgtgtcaaa accaactatg
     5401 accatccttt tgcctttgat acagacttga tgatcgagca gattaaggaa ttgttggcag
     5461 ggcgtccggt ggacatcccg acctacgact atacagagca tacacggagt agcaagacct
     5521 atcgtcagga gcctcaagat gtctttatcg ttgagggcat tttggtcttg gaggacaagc
     5581 gtctgcgcga tttgatggat atcaagattt ttgtggatac ggatgacgat gtgcgcatta
     5641 ttcgtcgtat caagcgtgat atggaggagc gtggccgtag ccttgatagc gttattaacc
     5701 agtacttagg tgtggtcaaa ccaatgtacc accagtttat cgagtcaact aagcgttatg
     5761 ctgatatcgt cattcctgaa ggggttagca ataccgtggc tatcgacctg ttgacgacca
     5821 agattgcaaa gattttggaa gaagctcgaa acagcaaata atcacatgtg gaggccttgc
     5881 ctcctttttc tatttttccc tcataatggt acataaatgg agatttttag gcatattttt
     5941 ggtataataa tacccatgaa agagcaagta aatgaatagt aggtggagat ggaaaagtat
     6001 ttatcggtaa caactttgac caagtatctg aaaatgaaat tcgataaaga cccatacttg
     6061 gaacgggtct atttaactgg tcaagtttcc aactttcgta aacgacctac tcaccaatat
     6121 ttctccctaa aggatgacca tgcagttatt caagcgacca tctggtctgg gatttatcag
     6181 aaattagggt ttgacctgga agaaggaatg aagatcaatg tgattgggcg tgtacaggtc
     6241 tatgaaccaa gtggtagcta ctccatcatc attgaaaaag ctgagcctga tggggttggg
     6301 gcgcttgcga ttcagtttga acaacttaag aaaaaattga cagaaaaagg cctgtttcaa
     6361 gaacgcttca agcaagctct accccaattt tctaagagaa ttggggtagt aaccagccgt
     6421 agtggagccg ttattcgaga tattatcacg accgtcagca ggcgattccc aggtgttgac
     6481 atccttcttt atcctaccaa ggttcaaggt gaaggggctg cggaggaaat tgctagaaat
     6541 attgcgcgtg ctaatcaacg ggacgatttg gatttgctca ttattggtcg tggaggtggt
     6601 tctattgagg atctctgggc ctttaacgaa gaaattgtgg tacgagctat ttttgaatct
     6661 cgtttgccag ttatctctag tgtggggcat gagacggatg tgaccttggc agattttgtg
     6721 gcagatcgac gcgctgcaac gccaacagcg gcggctgaac tggcaacacc tgtgaccaag
     6781 ttggatgtat taactcattt gcaaaatcag gaaaaacgga tggcaacggc agtccgaaat
     6841 gttctatcta agaaacaaga ggctttgaaa aaatgcagtc agtctgttat ctttagacaa
     6901 cctgagcgct tgtatgacgg ttatttgcaa cgcttggacc aactgcaact gcgtttgaaa
     6961 caaagtttgc gaactcggat ttctgataac aaacaattag ttcaagcaag aactcatcaa
     7021 ttagtacaat tatcacctgt taccaaaatc caacgctatc aagaccgttt aggacagttg
     7081 gacaagctct taggtagcca aatggcgtta gtttatgacg ccaaggttgc tgaggccaag
     7141 cgactttcgg aagctttgct catgttggat actagccgaa tcgtggcgcg tggttatgct
     7201 attgtcaaaa aagaagagtc cattgtagat tcggttgaga gtttgaagaa aaaagaccaa
     7261 gtaacgcttt tgatgcgaga tggtcaagta gaattagagg ttaaagatgt caaaacaaaa
     7321 gaaatttgag gaaaatctag cagaactgga aaccattgtc caaagtttgg aaaatggtga
     7381 aattgctctg gaagatgcga ttactgcctt tcaaaagggc atggtcttgt caaaagagct
     7441 ccaagctacg ctggacaagg ctgaaaagac cttggtcaag gtcatgcaag aagacggaac
     7501 agaaagtgat tttgaatgaa aaagcaagaa aaattagctc ttgtcgagtc ggctttggaa
     7561 gatttttatg gagaccagca gtttgcctct agtttacggg agtctgttct ctattctatt
     7621 catgctggtg gcaagcgtat tcggcctttt ctcttgttag aagttctgga agccttgcag
     7681 gttaccatca aacctgctca cgcgcaggta gctactgcct tggagatgat tcatacaggg
     7741 agcttgattc acgatgacct tcctgctatg gatgatgacg attatcgaag agggcggtta
     7801 accaatcaca agaaattcgg tgaagctatg gccattttgg ctggagatgc cttattctta
     7861 gacccatatg ccttgattgc gcaggcagat ttgccaagtc agattaaggt ggacttgatt
     7921 gccaacttat cccttgcttc aggtagtctg ggtatggtgg cagggcaagt tttggatatg
     7981 gagggcgaac accagcactt gtctttggaa gaacttcaga ttattcatgc caataagact
     8041 gggaagttac tagcctatcc cttccaagcg gcagctatta tagctgaatt gtcacctgaa
     8101 atgcaggtga agctgaaaac tgtgggtgaa ttgattggac ttgcttttca agtcagagat
     8161 gatgtactgg atgtgacagc tagttttgag gaaatcggca agacacctca aaaggatctg
     8221 caggcagaaa aatcaaccta tcctgccctg ttgggcttgg aagagtccat tgccttttgt
     8281 aaccaaaccc tggatcaagc taatgaaaaa ttagaagaaa ttgcccagca gcttcccttt
     8341 gaaacagaat cgattgtaag tgtagtagaa agtttgagaa tcaatggcta aggaaagagt
     8401 ggatgtacta gcttataaac aggggttgtt tgaaacgaga gagcaggcca agcgaggtgt
     8461 aatggctggc ctagtcgtag cagtccttaa tggagaacgg tttgacaagc caggagagaa
     8521 aattccagat gacaccgaat taaaactcaa gggagagaaa ctcaagtatg tcagccgtgg
     8581 tggtttgaaa ctggaaaagg ccttgcaggt ctttgatttg tcggtggatg gcgcgactac
     8641 gattgatatc ggggcctcta ctggaggttt taccgatgtc atgctacaga atagtgccaa
     8701 gttggtcttt gcagtcgatg ttggtaccaa tcagttggct tggaaattac gccaagaccc
     8761 acgagttgtt agcatggagc agttcaattt ccgctatgct gaaaagactg atttcgagca
     8821 ggagccgagc tttgccagta ttgatgtgag tttcatttcc cttagtctga ttttgccagc
     8881 cttgcaccgt gtcttggctg atcaaggtca ggtggtagca cttgtcaaac ctcagtttga
     8941 ggcaggacgt gagcagattg ggaaaaatgg aattattcga gatgctaaga ttcatcagaa
     9001 tgtccttgaa tctgtaacag ctatggcagt agaggcaggt ttttcagtcc ttggcttgga
     9061 cttttctccc atccaaggtg gacatggaaa tattgaattt ttagcgtatt tgaaaaaaga
     9121 aaagtcagca agcaatcaga tttttgctga gattaaagaa gcagtagaga gggcgcatag
     9181 tcaatttaaa aatgaataaa aaagagagac ttgaaaaaat tagaagattg gtgacagatt
     9241 atcaaatcgg cacgcaagaa gaaattgtag aacatttgaa agaagcaggt atcactgcca
     9301 ctcaggcgac ggtatcccga gatatcaaag agttaggtat tgtcaaaatt cctttgagag
     9361 acaacaccta tgtctacgaa ttaccaaaat caatcgtaaa aagtctgcaa ctggctgaag
     9421 acaatatcga atcggctgaa ttgatggata agatgatcaa tctccaagtt attccaggaa
     9481 atacggcttt tgtaaaagct cagttaatcg atacttttgc agacaagatt tttagttgtt
     9541 tgactgatga tagctcgatt ttagtcattg ccagaagtgg aagtctagca gaggaaatct
     9601 ttgaacaagt aaaaaattgg taggtctata tgttacttga aatttcgata aaaaactttg
     9661 ccattattga ggctatttcc ctcaattttg aaaaggggat gactgtcctg actggtgaaa
     9721 cgggtgcagg gaagtcgatt atcattgatg ccatgaatat gatgttggga gctcgtgcga
     9781 cgacagatgt tattcgtcat ggtgcaccaa aggcagagat tgaggggctt ttctcagttg
     9841 agaatagtcg tcttttacag gaaatttttg atgagcaagg tttagaatta ggtgatgaaa
     9901 ttatcatccg tcgggaaatc ttgcaaaatg gtcgtagtat cagccgtgta aatggtcaga
     9961 tggttaatct gtctgttttg cgagctattg ggcaacatct tgtagatatt catggtcagc
    10021 atgaccatga ggagttaatg cgtccccaac tgcatatcca gatgttggat gaatttggtg
    10081 atgccgcttt ttgggacttg aaagaaacct atcaaacgag ttttgatgcc tatcggaaaa
    10141 tgcgcaagca ggttctggaa gtcaagaaaa accaacagga acacaaggaa cgtatcgaaa
    10201 tgttggaatt tcaaatggca gagattgagg cagcaaactt gcaggctgga gaagacttgg
    10261 ctctcaatca agagcgagat aaactcctca accacaaaaa tattgcggat acactgacca
    10321 atgcctacag tatgttggac aatgaagatt tttcaagtct ggccaatgtt cgttcagcta
    10381 tgaatgacat ggaaagtgtc gaagagtatg atcctgaata ccgtgaaatt tcaagctctc
    10441 tgtctgagac ctactatgtt ttagaagaca ttagcaaacg tttggaagct atcattgagg
    10501 accttgattt tgatggcaat cgcctgatgc aggttgagaa tcgtttggac ctccttcata
    10561 ctattactcg taagtatggt gggactgttg atgatgtttt gctttatttt gccaagatta
    10621 cggaagaata caatctcttg acaggcaata atctttcgtc tgaggacatg gaagcagagc
    10681 ttaagaagtt ggaagtcaat cttgtcaatt tggcaggtca acttgcttct gctcgtcata
    10741 atttggctca gcaactcgaa gctgagatta aacaagaact gcaagatctt tatatggaaa
    10801 aagcccagtt tcaggttcat tttagtaagg gaaaattcag tcgtggggga aatgaaatgg
    10861 ttgagtttta tatttcaacc aaccctggag aagactttaa acccttggtt aaggttgctt
    10921 ctggagggga attatctcgt ctcatgttag ccattaagtc tgccttttca cgtaaagaag
    10981 gcaagactag cattgtcttt gatgaggtgg atacgggagt ttcaggtcgt gttgctcaag
    11041 ctattgctca gaaaattcat aaaattggtc agcatggtca ggttttggct atctcccatt
    11101 tgccacaagt aattgcgatt gcagattatc aattctttat tgagaagatt agtaatgacc
    11161 attcaacggt ttcgactgtt cgtctcttga cagtcgaaga gcgagtggag gaagttgcca
    11221 agatgttggc aggtgatgat gtgacagaag cagccctgac gcaagccaga gaattgttga
    11281 gaaacaggga gaaataagat gacagattat tatgtaattg gagatgttca cggaaaagct
    11341 gggatgctgg aagaccttct taaaacctgg gatggtcaga cccagttgct ctttctaggt
    11401 gatttgattg acagaggtga ggatagtcac cgtgttcttg aaatggtcaa ggacttggtg
    11461 gacaatcaag gggctatctg tttgtctgga aaccacgagt atatgttttt gacttggcta
    11521 gatgacccag aagaaagtta tgaccattat cgtcgcaatg gtggagatac aaccattaac
    11581 tctatcctag gtcgtccctt ggatgcacca gttgatggag tagaagatgc caagcgggtt
    11641 gccgctgaag cgtcagactt ggtcgaattc attcgtcaaa tgccatttgt agtagagaca
    11701 gacaagtata tatttgttca cgcaggtatt gatttgactt tggacgactg gcatgaaaca
    11761 acagattata aaaaagtatg gcttagaaaa ccattccacg gagctgaaaa tcatactgga
    11821 aaaaccattg tcttcggtca tacaccggtc tatggtttgt tacagcaaga acgcggtaca
    11881 tctgagcttt ggactacaga agatggcaag attggaatgg atggaggagc tgtttatggt
    11941 ggtgtccttc acgggattgt ctttacagac caaggaatga cagaacacca ctttatcgaa
    12001 aatgacggct ttgtcgctga agattagtac tcctagcagg gtatggtctt gtcaaaatat
    12061 caaaaacaat ttataataaa tagataccct gaaaggaaga gaatcatgaa cttagaagaa
    12121 ttgaaaaaac gacaggggaa gatccgtaac ttctctatta tcgcccatat tgaccacggg
    12181 aaatcaactc tagcagaccg cattttggaa aaaacagaga cggtttcaag tcgtgaaatg
    12241 caggcccagc ttttggatag catggatcta gagcgggaac gtggaattac tattaagttg
    12301 aatgccatcg agttgaatta cactgcaaaa gatggggaaa cttatatttt ccacttgatt
    12361 gacacaccag ggcacgttga ctttacctat gaagtttcac gttcgctagc tgcctgtgag
    12421 ggtgctattt tggtggtcga tgcggctcaa ggaattgagg ctcaaactct tgccaacgtt
    12481 tatctggctt tggataatga tttggaaatc atgcctatca ttaataaaat tgacctgccg
    12541 gctgcagatc cggagagcgt gcgtacagag attgaagatg tgattggttt ggatgccagt
    12601 gaagcagttt tggcttctgc caaggctggt attgggattg aagaaatcct cgagcaaatt
    12661 gtagaaaaag taccagcacc aacgggtgat gtgacggcgc cacttaaggc cttgattttc
    12721 gactctgttt acgatgctta ccgtggggtt atcctccaag tgcgtgtcat ggacggagtg
    12781 gtcaaacctg gtgataagat tcagctcatg agcaatagta agacctttga tgtggccgaa
    12841 gtcggtattt ttacaccaaa agcggttggt cgtgatttcc ttgcgactgg tgatgttggt
    12901 tacattgcgg cgtctatcaa gacggttcag gatactcgtg tgggtgatac cgttaccttg
    12961 gcaaccaatc ctgcggcaga accattacat ggttataagc agatgaatcc tatggtcttt
    13021 gcgggtctct acccaatcga atcaaacaag tacaatgacc tgcgtgaagc gcttgaaaaa
    13081 ttgcaactga atgatgctag tcttcagttt gaaccagaaa catctcaggc acttggattt
    13141 ggtttccgtt gtggatttct tggacttctc catatggatg ttatccagga acgtttagag
    13201 cgtgagttca atattgatct catcatgaca gctccgtctg ttatttacaa agttaatttg
    13261 accgacggtg agtctatgga tgtgtctaac ccatctgagt ttccagaccc aactaagatt
    13321 gcgaccattg aagagcctta tgtcaaggcg caaatcatgg taccacagga gttcgtcgga
    13381 gcagtaatgg agctagctca gcgtaagcgt ggggactttg tgactatgga ctatattgat
    13441 gataaccgtg tcaatgttat ctatcaaatt cctcttgctg aaatcgtctt tgacttcttt
    13501 gataaactta agtcttcgac acgtggttat gcaagttttg actacgaatt gtcagaatat
    13561 cgcccatcta agctagtgaa aatggatatc cttctcaacg gagacaaggt ggatgccctc
    13621 agctttatcg ttcataagga ctttgcttat gaacgtggga aactcatcgt tgataagctc
    13681 aagaaaatca tccctcgcca acaatttgag gttccaatcc aagcggctat tggacacaag
    13741 attgtcgctc gtactgatat caaggccctt cgtaagaacg tacttgctaa atgttatggt
    13801 ggtgacgttt ctcgtaagcg taaactcctt gaaaaacaaa aagctggtaa gaaacgcatg
    13861 aaatccatcg gatcagttga agttccgcaa gaagccttcc tcagcgtctt gagtatggat
    13921 gaagaataag ttatcagaaa tgcctttcct tgttcacagg aaatttatat aagaatcaat
    13981 agtaaagcag gcttagatgg tctgcttttt tagtttttat actcttcgaa aatctcttca
    14041 aaccacgtca gcgtcgcctt accgtatgta tggttactga cttcgtcagt ttcatctaca
    14101 acctcaaaac tgtgttttga gtaacctgcg gctagcttcc tagtttgctc tttgattttc
    14161 attgagtatt agaacagaaa aatgcttgga gtatttgttt gtgtgtttat ttttatataa
    14221 caaactataa acacaacaaa aatataaaaa aagagacaaa aaagaacaga aagtaattaa
    14281 caacgatttc atatagtgtt atacttatag cataaagtta atggaaagaa gggaaaacct
    14341 tatggtatta gattatttct ttgacaaaaa ccttgtgttt tgcttagaag cggataatca
    14401 agaataactc tttgatcagg tagcaagctt gttggaggaa cgagaaattg taactccaac
    14461 ttatcgtgaa gctttgatca cgcgtgaaaa gtcatttcca actggtttag atatggaatt
    14521 tctaggaaag gacttgcaaa tgtaatgatt cctcacacag atattgttca taatctagct
    14581 gagaaagtgg tggttgttcg attagagaaa ccggtgactt tccataatat gattgcgcca
    14641 ggtaaggaag tagaagtatc cttgctcttc tttatcatca ataattcaag ttcaagtcaa
    14701 acgaacattc ttgctcagtt gatggacttt ttcacaggaa atggacatct tgaagaccta
    14761 tcaaaaattt ccgaaccaga aaaactttat gcttatatag atgaagcaat cgcttaatct
    14821 tgtctattaa aaaataaaat cggaggaagt ctatatgatt aaaattcttg ctgcctgcgg
    14881 tgcaggtgtt aactcaagtc accaaattaa aagtgctcta gaagaagaac tttcaaaccg
    14941 tggttacgat gttcactgtg atgcagttat ggtgaaagat gtaaacgaag accttatgaa
    15001 aggttacgat atctttacac caatcgctgc aacagacctt ggttttgaac caggtatccc
    15061 agttatcgaa gctgggccaa tcttattccg tatcccagca atgagcgttc cagtatttga
    15121 caatattaga cttcctgcga aacaaaatat ggtatagtag ttctatgaat gatgaagcaa
    15181 gtaaacaact aactgatgca cgatttaagc gtcttgttgg tgttcagcgt accacttttg
    15241 aagagatgtt agctgtatta aaaacagctt atcaacttaa acacgcaaaa ggtggacgaa
    15301 aacctaaatt aagcctagaa gaccttctta tggccactct tcaatagtgc gagaatatcg
    15361 aacttatgaa caaattgcgg ctgattttgg tattcacgaa agcaacttta tccgtcggag
    15421 ccaatgggtt gaagtaactc ttgttcaaag tggtgttacg gtttcaagaa ctcctctcag
    15481 ctctgaggac acggtaatga ttgatgcgac ggaagtacaa atcaatcgcc ctaaaaaaga
    15541 attagcgaat gattctggta aaaagaaatg ccacgctatg aaggctcaag cgattgtcac
    15601 aagtcaaggg agattgtttc tttggatatc actgtgaact attgtcatga tatgaagttg
    15661 ttcaaaatga gtcgcagaaa tatcggacaa gctggtaaaa tcttggctga cagtggttat
    15721 caagggctca tgaagatata tcctcaagca caaactccac gtaaatccag caaactcaag
    15781 ccgctaacag ttgaagataa aacctataac catgcgctat ctaaggagag aagcaaggtt
    15841 gagaacatct ttgccaaagt aaaaacgttt aaaatgattt caacaaccta tcgaaatcat
    15901 cgtaaacgct tcggattacg aatgaatttg attgctggca ttatcaatca tgaactagga
    15961 ttctagtttt gcaggaagtc taataaagaa actagcaagg tcaggcctta ctttattggt
    16021 ggacatccag gatttaattg tcctctactt gatgatgaag tctatgaaga ttattatcta
    16081 gagtttgaga aagaagagac ttgctctgtt ccacgtcctt tcccagaaac aggtatgttg
    16141 gatttccaag atagaagtcc atggctagag ggacaaaaag aaatagatct tagttatgat
    16201 cttttcagca aagatgcagt gactttggat gaattgcaat ctcgaacaat tgcccttcgt
    16261 tctcttaaac atgatagggg attgaaagtg cattttgcag aatttccaaa cctcatcatc
    16321 tggtcaactt tgaacaaggg acctttcatt acctttgaac catggtctgg cttgtcaaca
    16381 ttccttgaag aaggagatca tttagaagat aagaagaatg tttgtctctt agaagccaat
    16441 caggttgaag aattagggtt tgagatagaa gttttcccaa atttcaagtt gaagttagcc
    16501 acccaaaaga aattcacttg gcgacttgta gtccaagcat tttttagggt agttgttaat
    16561 ccaattttcg ataaaagcta cttctttcgg agtcgttttc ttggttcctt taggtaacca
    16621 tctccgaatt aatcgattat gattttcatt tgaacctctc tcccatgaag agtaagcatg
    16681 tgcgtagtag atatgttcct caggaaatac ctcagacaat cgtttgaact ccgaaccatt
    16741 atctgcagta atggacagaa tacgatgctc ccctaatagt aacgtaagcg cctgattgac
    16801 agattcagca gttttatttg gaattaacct tataatttgg tgtctgctcc gccggtcggt
    16861 taagactaac aggcaataat tttttatctt agtcagtagg acggtatcaa tttcataatg
    16921 accattttcc aagcgaagat taataacgtc aggacgttct tcgatagatt tacctgccgg
    16981 cttaaagttc ggactagctt gcttcttgac acctttcctt tttctgggat aaagcatgtc
    17041 ggccttcgtc aatcctaaat gaccattatg aaaccagtag tagatggttg aaataccaac
    17101 tttcacttgc ttcttgttaa ccatcatttc aggcgaaaat ttttgcttat gatagtgtaa
    17161 gatcttctct ctgatttcct ttgttaaaat taactttttc accgaccgtt ttcgattgaa
    17221 ttggtaaaca gtttgtgcgt aatcggcaga atagaccttt ttgtatagcc cttttctcac
    17281 ttgttgtaaa gttgtacctc ttttgacttc agtatgaatc gtttgaggcg cctttcctaa
    17341 caagcctgca atttcacgat tggacttatt ttcattcttc caccgctcaa tcaagcgacg
    17401 gttatctatt gtcaaatgtt tcccttttgg ggtataatgt tcttgcatct ctgtgccttt
    17461 ccttgtgttt gtggtgaaca acaagtatag cacagaggtg ttttcttata ccttaaatca
    17521 catttcattt gacaacagga acccttgaac ctgttttttc agctaaacca aggctatgat
    17581 tagccttggc cacctagcct aacagtttca aacctgttat caaatgaaat catcaactta
    17641 ctcaaacata gtgaaacatc taattcttga ctaaggtaag gtggctaact tcattataga
    17701 actttcagag atagaagttt tataaaaaag taaaaaataa ataacaaaaa caaacacaaa
    17761 ctgttgactt cttcaaacaa tagtagtata ttatgtttgt gaggactaat tgactgtttt
    17821 ttaaagacag ccaatacact gctggaatcc agcatagaaa aaataaaaag gagtatacaa
    17881 tatgtctatt gttatcggtg cagatgctgc aggtttgaga ttgaaagaag ttgtgaaaga
    17941 cttcttagaa aaagaaaact tccaccttgt ggatgttaca gctgaaggtc aagactttgt
    18001 tgatgtgact ctcgctgttg ctgcagaagt aaacaaagaa gaacaaaacc ttggtatcgt
    18061 gattgatgct tatggagctg gtccatttat ggttgcaact aagatcaaag gaatggttgc
    18121 tgcagaagtt tctgatgaac gttcagctta tatgactcgt ggccacaaca actcacgtat
    18181 gatcactatg ggtgcacaac ttgttggtga tgaattggct aaaaacatcg ctaaaggatt
    18241 tgttaatggt aaatacgacg gtggtcgtca ccaaatccgg gttgacatgt tgaacaaaat
    18301 gggctaatta gattatagta agaaaggtaa gttaaaaatg agaattgcaa ttggatgtga
    18361 ccacatcgta acagatgaaa aaatggcggt ttcagaattt ttgaaatcaa aaggatatga
    18421 agtcattgac tttggtacat atgaccatac acgtactcac tacccaatct ttggtaaaaa
    18481 agtaggggaa gctgtaacta gcggtcaagc tgatcttgga gtatgtatct gtggtactgg
    18541 tgttggtatc aacaacgctg taaataaagt tccaggtgtt cgttctgcct tggttcgtga
    18601 tatgacaaca gccctttatg ctaaagaaca attgaacgct aacgttattg gttttggtgg
    18661 taagattact ggtgaattgc ttatgtgtga tatcatcgaa gctttcatcc atgctgaata
    18721 caaaccaact gaagaaaaca aaaaattgat tgcgaaaatt gaacatgttg aaagtcacaa
    18781 tgctcaacaa atagacgcaa acttcttcac tgaattcctt gaaaaatggg atcgcggaga
    18841 ataccacgac taagaggtaa cctatgattt taacagttac aatgaaccca tccattgata
    18901 tttcctatcc cttggatgag ttgaagattg atactgtcaa tcgtgtggtg gatgtaacca
    18961 aaacggctgg tggtaaggga ctcaatgtta cccgagtact ttcagaattt ggcgattctg
    19021 ttcttgctac tggtttagtg ggtggcaaac ttggtgagtt tttggttgaa catatcgata
    19081 atcaagtaaa gaaagatttc ttctcaattc agggagaaac tcgtaactgt atcgctattc
    19141 tccacggaga caaccaaaca gaagttcttg aaaaaggtcc tgaagtattg gaacaggaag
    19201 gtcaagactt tttggaacat ttcaaaaaac tcttggagtc agttgaagta gtggccatct
    19261 caggtagtct gccagctggc cttccagttg attactatgc gagcttggta gaacttgcta
    19321 atcaagctgg caagcctgta gtcttggact gctcaggtgc agcacttcag gctgttcttg
    19381 aatcacccca taaaccaaca gtcatcaaac caaataatga agaattgtct cagcttcttg
    19441 gaagagaagt ttctgaggat ttggatgaat taaaagaagt acttcaagaa cctttgtttg
    19501 cagggattga atggattatc gtttcacttg gtgccaacgg tacttttgcc aaacatggtg
    19561 acactttcta caaggtagat attcctagaa ttcaggtggt aaatcctgtt ggatctggag
    19621 actctactgt ggcaggaatt tcttcaggac ttcttcacaa agaatcggat gcagaattac
    19681 tcatcaaggc aaatgtcctt ggtatgctca atgctcaaga aaaaatgact ggtcatgtca
    19741 acatggccaa ctatcaagtt ctatatgatc aattaatagt aaaagaggta taaaatggct
    19801 ttaacagaac aaaaacgtgt acgcttagaa aaactttctg atgaaaatgg tatcatctca
    19861 gctcttgcat ttgaccaacg tggtgctttg aaacgcctca tggctcaaca ccaaacagaa
    19921 gaaccaactg tggcccaaat ggaagaactt aaagtcttgg tagcagatga attgactaaa
    19981 tacgcttcat ctatgcttct tgaccctgag tatggacttc cagcaactaa agctcttgat
    20041 gaaaaagctg gtcttctcct tgcttatgaa aaaacaggtt atgacacaac aagcacaaaa
    20101 cgcttgccag actgcttgga tgtctggtct gcaaaacgta ttaaagaaga aggtgcagat
    20161 gcagttaaat tcttgcttta ctatgatgta gatagctcag acgaactcaa tcaagaaaaa
    20221 caagcctaca tcgaacgcat cggttctgag tgtgtggctg aagatatccc attcttcctt
    20281 gaaattcttg cttacgatga aaaaattgcg gatgcaggtt ctgtagaata cgcgaaagta
    20341 aaaccacaca aagttatcgg cgctatgaaa gtcttttcag acccacgctt taacattgat
    20401 gtcttgaaag ttgaagttcc tgttaacatt aaatatgttg aaggcttcgc tgaaggtgaa
    20461 gtagtttata cacgtgaaga agcagcagcc ttcttcaaag cgcaagatga agcaacgaac
    20521 ttgccataca tctacttgag tgctggtgta tcagctaaac tcttccaaga tactcttgta
    20581 tttgctcatg aatcaggtgc aaactttaac ggagttcttt gtggccgtgc aacatgggct
    20641 ggatcagttg aagcatacat caaagatggt gaaacagcag ctcgcgaatg gcttcgcaca
    20701 actggatttg aaaacattga tgagctcaac aaagttcttc aaacaacagc aacttcatgg
    20761 aaagaacgtg tgtaagaaag tcctcctagt ttaggaacat gaatctaaaa aaatttaaaa
    20821 aaagttgtat gtaaaggttt acaaaataac ttacttgtgc tatacttaaa tcacaagtta
    20881 atacaaggtg agtgttacta agtaatatta ggcatgatca caggtgaatt agaaatcagc
    20941 tgattttcta gttcatttgt ggtcattttt tgtactcata tacctttaag atataaaagg
    21001 aggttgacat gtatcgaatt ctaaatccaa tgaatcacaa tgtctcgctt gtcagaaatg
    21061 ataagggaga agaggtgatt gtaattggta aggggattgc attcggaaag aagaaggggg
    21121 atttgattgc tgaaaatcag gttgagaaaa tctttcggat gaagaccgaa gagtccagag
    21181 aaaactttat ggctcttctc aaagatgttc cgcttgattt tatcacagtg acctatgaaa
    21241 tcattgataa gctatcaaag aaatatcatt atccgattca agagtatctc tatgtaacct
    21301 tgacagatca tatttactgt tcttatcaag ctctaactca aggaaggtac aaggatagta
    21361 atctgccaga tatttctgct aagtatcctg tcgcttttca aatcgcaaat gaagcttttg
    21421 aaatttactg tcagaagcta gcagatcatt ttcctgagga cgaaattatt cggattgctt
    21481 atcatttcat taatgctgaa ggtgaaaatg aagtggaact tgtggagtcg attgataaga
    21541 ggaaagaaat tctcaggaat gttgaagaag ttttaacgga ctatgcaatt caacgaacta
    21601 aaaagaataa ccatttctat gatcgcttta tgatccattt gaattatttc ttggattatt
    21661 tagacagatc tagagatgat aaccaatcac ttctggatat ggaagatcat attaaacaat
    21721 cctatccaaa agccttcgag attggttcca agatctatga tgtgattacg caacatacgg
    21781 gtcttgattt gtataaaagt gaacgagttt atctagttct acatatccaa cgtttattgt
    21841 cataaaaatt tatttaaaac tatataagga gaattctatc atgaatagag aagaagtaac
    21901 attgttaggt tttgaaatcg tagcctatgc tggcgatgct cgttcaaaac tattggaagc
    21961 cttgaaggct gctgaagctg gtgattttga aaaagcggac gctctggtag aggaagctgg
    22021 tagctgtatt gcagaggctc accacgcgca aacaagtcta ttgactaagg aagcttctgg
    22081 tgaggactta gcgtatagtg tgaccatgat gcatggtcaa gatcacttga tgacaactat
    22141 cttgttaaaa gacctaatgc accatttaat tgaactttac aagagaggag ttaaataaaa
    22201 tggataagtt aataattttt attgagaaag gaaagccttt ctttgagaaa ttatcgagaa
    22261 atatatactt aagagcgata aaagatggtt ttatttccag tatgccagca gtattattct
    22321 caagtatttt tatactaata gctgctgtgc ccaatatttt tgggtttaaa tggtctgatg
    22381 aacagttagc ttttattttg aaaccttaca actactcaat ggggatttta gctctcttag
    22441 tagctgggac aactgcaaaa tcgttaacag attcagttaa tacacgtagt atggagaaaa
    22501 ccaaccaaat caactacatg tcaacttttt tagcagctgt tgttggattg ttaatactgg
    22561 cagctgatcc aattgaaggt ggatttgcta atggtctttt aggtactaga ggattactta
    22621 ctgcattttt ggcagctttt attacagtaa atatctataa agtatgtatt aaaaataatg
    22681 taaccattag acttcctgaa gaggttccac caaatattgc acaagttttt aaagatgtta
    22741 ttccgtttgc cttatctgtt ctttcaatat atggattgga tttaattgtt agaaatattt
    22801 ttggtacaaa tgtagcagaa tctgttggta aaatattagc ccctctattt tcagctactg
    22861 atggttatat cggtttagct attgtatttg gtgcttatgc tttcttttgg tttgttggaa
    22921 ttcatgggcc atctgttgta gaacctttaa ttgtagctat cagttatgca aatatagaag
    22981 ctaatgttca gcttgtgcaa gctggtatgc acgcagataa aattttaaat ccagttactc
    23041 aaacttttgt tgtaacaatg ggtggtactg gtgcaacact agtagttcca tttatgttta
    23101 tgtggttatg taaatcaaaa agaaatagaa ttgtcggacg tgcgtctgta gttcctactt
    23161 tctttggcgt aaatgaacca atcctatttg gtgctccaat tgttttaaat cctatcttct
    23221 ttattccgtt tgttactgct cctattatca atgtttggat tatgaaattt tttgtagatg
    23281 ttctacaaat gaatagtttc agtattattt taccttggac aacacctgct ccaattggta
    23341 ttgttatggg aacggcgctg gctccattgt cattcgtctt ggctataact ttaatcatta
    23401 tcgacacttt aatctattat ccatttgtta aagtttatga ccatcaaatt ttagaagaag
    23461 aacggaaagg aaactcttca tctgaattga aagaaaaagt tgctgcaaac ttcaacactg
    23521 caaaagcgga tgctattctt gaaaaagcag gtgtcgatgc agcacaaaat accatcactg
    23581 aagaaacaaa tgtcctcgtt ctctgtgctg gtggaggtac aagtggactc cttgcaaatg
    23641 ctttgaataa ggcagcagca gaatacaatg tccctgtgaa agcagcagca ggcggctatg
    23701 gtgctcaccg tgaaatgtta ccagagtttg atttggttat ccttgctcct caagttgctt
    23761 caaactttga agatatgaag gcagaaacag ataagctcgg tattaaacta gcgaaaacag
    23821 aaggcgctca atacatcaaa ttaactcgtg atggaaaagg tgccctagca ttcgtacaag
    23881 aacaattcga ttaaggctag gaactgtgaa acagtctcct atcgttacgg aaatcgctat
    23941 ggcgaatttc ctaatcgcct tattaattcg tcggtaaaaa gatatcgttt ttacctcctc
    24001 atgtcacaat tcggtgactt ggtacaagaa gtgagatgga gaaggatggc tcactgactc
    24061 ctctcctctc acttttactt tatttaaatc aagaaatagg tgaaaaaaat gacaaaaaca
    24121 cttccaaaag actttatttt tggtggcgca acagctgcct atcaagcaga aggtgctaca
    24181 catactgatg gtaaaggacc agtagcgtgg gataaatatc ttgaagataa ctactggtac
    24241 actgcagaac cagccagtga tttttacaat cgatatccag ttgatctcaa gctagcagaa
    24301 gagtatggtg tcaatggcat tcgaatttct attgcctggt cacgtatttt cccgactggt
    24361 tatggtcaag taaatgctaa aggtgttgag ttttatcata atttatttgc agagtgtcac
    24421 aaacgtcatg ttgagccctt tgtaactctt catcactttg acgcgccaga agctctccac
    24481 tcaaatggag acttcttaaa ccgtgaaaat atcgaacatt ttgtagacta cgctgccttc
    24541 tgttttgaag aatttccaga agtaaactat tggacaacct tcaatgaaat tggaccaatc
    24601 ggtgatggtc aatatttggt tgggaaattc cctccaggta tccagtacga ccttgccaaa
    24661 gtctttcaat cacaccacaa tatgatggtg tctcatgcat gcgcggtaaa attgtacaaa
    24721 gagaaaggct ataaagggga aattggtgtt gttcacgccc tgcctactaa atatcctcta
    24781 gatcctgaaa atccagcaga tgttcgtgca gcagagttgg aagatatcat ccacaataaa
    24841 ttcatcttag acgcaactta tctaggtcgc tattcagctg aaaccatgga aggtgtcaac
    24901 catatcttat cagtcaatgg tggtagtttg gatcttcgtg aagaagattt tacagcatta
    24961 gaagctgcaa aagacttgaa tgatttccta ggaatcaact actatatgag tgactggatg
    25021 gaagcctttg atggagaaac tgaaattatc cataatggta aaggtgaaaa aggaagctct
    25081 aagtatcaaa tcaaaggtat tggtcgtcgt gtagctcctg actatgtatc acgcacggat
    25141 tgggattgga ttatctaccc tcaaggtttg tatgaccaaa tcatgcgtgt gaagaaagat
    25201 tatcctaact acaagaagat ttacatcact gaaaatggtc tcggctataa agatgagttc
    25261 gttgataaca ctgtttacga tgatggtcgt attgattacg tgaaacaaca cttggagatc
    25321 ttgtctgatg cgattgcaga tggagctaat gtaaaaggtt acttcatttg gtcattaatg
    25381 gatgtcttct catggtcaaa cggttatgag aaacgttatg gtctcttcta cgtagatttt
    25441 gaaactcaag aacgttatcc taagaaatca gctcactggt acaagaaagt agcggaaact
    25501 cagattatag actagtagaa ttagtcatta gatatagaat tttagtgagt caaaaagatg
    25561 ttcaaagatt ttatccaatc tatttatgaa aaaaagttta tattataaat ttcgaaaaat
    25621 gctctcaaat accgtgtttg acgagtgaag aattgaaaag tcttggaaaa tggtatgtct
    25681 cgactggtaa agaatggatt tgtcattcag atgatgagct ggaagaattt aaaaatctat
    25741 ttttaaattt tatcaatcct gaagaatggg atactatctc ctttgattca gattttatgc
    25801 cgtttcaaca atcgtaacca atttctcaaa aaagttaaat cttatattta gtactctgta
    25861 aaactcttat ctaatcacgt tgcttatact caatgaaaat caaagagcaa ctttaaacta
    25921 ggaagcgagt cgcagatttc tcaatgcata gctttgagga attgggcaaa aagtctttga
    25981 tatagaaaaa agcatagtat caggtgttga aacacctgat actatgcttt ttattgtggg
    26041 aagatttact ttttttcttc tgaaattgag ttgttaccca ggctctttca gtttattaag
    26101 gcttgatgac tttaatgtgt ttagatagct taaaaaggat tgaatcactt agtttagaat
    26161 ctgaaacaat agtatcaaga tttgatatat tataaaaagt ataaaaatca aacttattga
    26221 acttactatg atctgcgagt aaatattttt tattagaatt atttaaagcg atgcgttgag
    26281 cctctccctc ttcctcgcta aaagtagcta gagctccgtt ttgaatacca ttacagctaa
    26341 cgaaagcttt agaaaattgg agattagaga gattttgtag ggtcaatgtg ccaacaaaag
    26401 cacctgtaat atcgcgataa tttccaccta tcaaaatcaa atctgttaat tttcgttcgc
    26461 ttaaaatcag aaaaacaggt agactgttgg ttacgacgcg gatattgtca ataggcaact
    26521 cacgcgcaaa aaactctaat gttgttcctg gtccaatgaa aatagtttct ctttcttcta
    26581 ctagactgcc tgcaaaatgg gctatttctt gtttttctgc cgtttggagg gcttgttttt
    26641 caatatttga tcgctcatta gtcaaaaggg agttggttcg aagtttttca gctccaccat
    26701 gcacacgaat cagcaaatct ttatcagcta attcctgtaa atagcgcctt gcagtcatat
    26761 ctgaaacggc tatttcgtcc ataatctgtt taactgttat ggttccttta ctatttacta
    26821 tctctaaaat tttggttaat ttttcttgtt tgagcatatt atcacctcgt ttcctactac
    26881 tatcttacca taaacaaact catcattcaa atacaaaaac aacaaaatga aacaaaaaca
    26941 aaaatatcga agtttgtttt caaaactttc gatatttttg ttgggttatt attttgttgt
    27001 ttctagttta ctttttgatg gttaagagtg gtggagaatt atactcaatg aaaatcaaag
    27061 agcaaactag gaagctagcc gcaggctgta cttgagtacg gcaaggcgaa gctgacgtgg
    27121 tttgaatttg attttcgaag agtattagtc caaaccgtag ttgtagtcat catcttgcat
    27181 ggcttcaact tcgccaagaa ggtaaccatt tccgacttga gagaagaagt catggttgga
    27241 agttcctgtt gaaataccgt tcataacgat tgggttgaca tcttcagctg aatctgggaa
    27301 aagtggatct tgtcccatgt tcatgagagc tttattggca ttgtagcgaa ggaaggtttt
    27361 aacctcttca gtccaaccaa caccgtcata aagactctct gtgtagcctt cttcattttc
    27421 ataaagagta tagagtaggt cgtacatcca ttctttgagt ttttcttgct cttcttcagg
    27481 taattcattg aaaccaagtt ggaatttgta accaatgtag gttccgtgaa cagactcgtc
    27541 acgaataatc aatttaatga tttctgcaac gttggcaagt ttgttgttac cgagatagta
    27601 gaggggagtg aagaaaccag agtagaagag gaaggtttcg aggaagacgc tggcaacttt
    27661 cttttcaagt gggctgccgt ttaggtagat ttcgttgaca atctcagcct tcttttgtag
    27721 gtaaggattg gtattggtcc attcgaaaat ttcttcaatc tcagccttag tattcaaggt
    27781 agaaaagatt gatgagtaag atttagcgtg gacagattcc ataaattgga tgttattgaa
    27841 aacagcttcc tcatgtggtg tacggatgtc tgcgcgaagg gcttgaaccc cagtttcaga
    27901 ttgcatagtg tcaagaaggg ttaaaccacc aaaaactttt ccgaccaagt ctttctcttt
    27961 gttagatagc tttctccagt catccaagtc gtttgataag ggaatacgtg tatcgagcca
    28021 aaattgctcc gtcagttttt cccaagttga tttgtcgatg acatcttcga tggcattcca
    28081 gttaatggct ttgtagtaag tttccattta aaatctcttt ctgtgtttag tattgcgaac
    28141 tcacaattat ttctacttta ccataattct ataggagtat cgcacaaaaa gtcggaagcc
    28201 cgacttttaa aatgttacat aaattatgtt atgacatagt agatttgatt ttatcagtgc
    28261 tgcttaggga aaaatagtgt ttctatgcta gaaactaaat cacacagctt tcacattggt
    28321 tggcgccgac ttctccaccg tcatctgtaa aggtacggac gtagtagata gacttgattc
    28381 ccttgttaaa ggcatagtta cgaaggatgg acaagtcacg tgtcgtttgt ttattttccc
    28441 tcttccattc gtaaaggcct tttggaatgt cactacgcat gaagagggtg agtgaaagtc
    28501 cttgatccac gtgttcagtc gcagcagcgt aaacatcgat gactttacgc atatccatat
    28561 cgtaggcaga agtgtagtaa ggaatggttt ctgtagacaa gccagcagca gggtagtaga
    28621 ttttaccaat tttcttttcc tgacgttctt caatacgttg cgtaatcggg tggatagaag
    28681 cagaaacatc gttgatgtag ctgatagaac catttggcgc tacagcaagg cgattttggt
    28741 ggtaaagacc atcctcttga accttgtcgc gaagttcagt ccaatcagca acaccaggga
    28801 taaaaacatt tttgaagagt tctttaacac ggtctgatgt tggaacaaat tcaccagtta
    28861 catacttgtc aaagtaactt ccgttagcat agtctgattt ttcaaagttg tggaaggtaa
    28921 taccacgttc acgcgcaata ttgtttgact ctaccaaggt ccagtagttc ataagcataa
    28981 agtagatgct tgtaaattca acagactcag gtgaaccata ttcaatgagt tgttgggcaa
    29041 ggtagctgtg cagtcccatg gcaccgagac caaaggtgtg ggcttggcta tttccatggt
    29101 caatcgttgg tacagctacg atatgtgaac tatctgtaac gaaagtaagg gcacgaacca
    29161 tagcacggat agaacgacca aaatcaggtg aagtcatcat gttaaccacg ttggttgaac
    29221 ccaggttaca tgaaacatct gttcccattt gaaggaattc ttgagcatcg ttgatcaagc
    29281 ttggttcttg aacttgaaga atctcagaac acaagttact catgataatc tttccatcga
    29341 caggatttgc acggttagcc gtatcgatgt tgactacata aggatagcca gactcttgtt
    29401 gcaatttaga gatttcagtt tccaaatccc gcgccttgat ttttgtcttg cgaatatttg
    29461 gatttgcgac caattcatcg tatttttcag taatgtcgat gtaattgaat ggcacaccgt
    29521 attctttttc tacagagtaa gggctgaaga ggtacatttc ttcattttta cgagccaatt
    29581 cgtagaattt atcaggtact acaacaccaa gtgatagagt cttgacacgt actttttcat
    29641 cagcgttttc tttcttagtt gaaaggaaag cgatgatatc tgggtgaaag acgttgaggt
    29701 agacaacgcc ggcaccttga cgttgcccca attggttgga gtaagagaag ctgtcttcaa
    29761 aaagcttcat aacaggaacg acacctgaag cagctccttc atagcctttg ataggtgcac
    29821 cagcttcacg aaggttgctg agggtaattc ccacaccacc accaatacgt gaaagttgaa
    29881 gagctgagtt gatagaacgt ccgatagagt tcatatcatc cgtcacttgg attaggaaac
    29941 aagataccaa ctccccacga cgagcacgtc cagcattcaa gaaggaagga gtagcaggtt
    30001 ggtagcgttg gtggatgatt tcattggcaa tatcgattgc aacagcttca ttcccatcag
    30061 cgaaataaag ggcgttgaag aagacacggt cttccatatt ttcaagatag tattcaccgt
    30121 cattagtctt taaggcatat tgattgtaaa atttataagc tgccatgaat gacttgaatt
    30181 ggaagttttg gtctttgata aattgagcca attcttccaa gaactctgga cggtatttct
    30241 tgataaaggc tgtttcgatg tagttgtgtt caatgaggta attgattttg tctttgattg
    30301 aatcaaaaac catagtgttt ggaactacat tttctttaaa gaaagcatcc aaggcttcct
    30361 catctttatg aagcatgatt tgtccattaa caggacggtt aatttcgtta ttaagacgga
    30421 agtaagtcac gtcttcaaga tgttttaatc ccataaaatt tcccttatct aattacaaaa
    30481 gaaaggcttc taagttagcc ctaaaagcag tttcttctgg atgatgtact aagattatgc
    30541 taattgtttc agttttcctg gttggaaacc tgaaaagact tcagttggtg tttggataac
    30601 aggagctgcg ctaaaaccga gctctttaac ttgatcgacg tactcaggtt gctcatcaag
    30661 attgatttca cgataagaga cattattact gtccaagaaa cgcttggtca ttttacattg
    30721 gacacaattg tttttagaat aaacggttac cattgtgtaa ctcctcttca aaatttaata
    30781 ctatcttagt atatcagaaa ataaaatttt gtcaatgatt taaactaaat atagtggtgt
    30841 tcttttgttg tttttatata taaacacaat atatagtgtt tgtgttgtga aatagcaatg
    30901 attatcctat aaattgtttt tgaagaaact atatcctgtg ttttgttatc taggatagaa
    30961 gattttcagc aagttatctg aaaggaaatt gaaggaaaat ccagaaaatg cttgaaaaaa
    31021 atcctagaag atggtataat actaaattgt aagggttatc acatataact caaaaaaaga
    31081 aagaacaaaa ggagagtcaa actatggctt ctaaagattt ccacgtagtg gcagaaacag
    31141 gtattcacgc acgtccagca acattgttgg tacaaactgc tagcaaattt gcttcagata
    31201 tcactcttga gtacaaaggt aaatcagtta accttaaatc aattatgggt gttatgagtc
    31261 ttggtgttgg ccaaggtgct gacgtaacta tctcagctga aggtgcagat gcagatgacg
    31321 ctatcgctgc aatctcagaa acaatggaaa aagaaggatt ggcataaggg aaatgacaga
    31381 aatgcttaaa ggaatcgcag catctgacgg tgttgcagtt gcaaaagcat atctactcgt
    31441 tcagccggat ttgtcatttg agactattac agtcgaagat acaaacgcag aagaagctcg
    31501 ccttgatgcc gctctacagg catcacaaga cgagctttct gttattcgcg agaaagcagt
    31561 aggtacgctc ggtgaagaag cagctcaagt ttttgatgct cacttaatgg ttcttgctga
    31621 cccagaaatg atcagccaaa tcaaggaaac tatccgtgcg aagaaagtga atgcagaagc
    31681 aggtctgaaa gaagttacag atatgtttat cactatcttt gaaggcatgg aagacaaccc
    31741 atacatgcaa gaacgcgcag cggatatccg cgacgtgaca aaacgtgtat tggcaaacct
    31801 tcttggtaaa aaattgccaa acccagcttc tatcaatgaa gaagtgattg tgattgcgca
    31861 tgacttgaca ccatctgata cagctcaatt ggacaaaaac tttgtaaaag cttttgtaac
    31921 caacattggt ggacgtacaa gccactcagc tatcatggca cgtacacttg aaattgctgc
    31981 tgtattaggt acaaataaca tcactgaaat cgttaaagac ggtgacatcc ttgctgttaa
    32041 cgggatcact ggagaagtga ttatcaaccc aacagatgaa caagcggcag aatttaaagc
    32101 agctggtgaa gcctatgcga aacaaaaagc tgaatgggca cttttgaaag atgctcaaac
    32161 agtgactgct gacggtaaac acttcgagtt ggctgccaat attggtactc caaaagacgt
    32221 tgaaggtgtt aacaacaacg gtgcagaagc tgttggactt taccgtacag agttcttgta
    32281 catggattct caagacttcc caactgaaga tgagcagtat gaagcataca aggctgttct
    32341 tgaaggaatg aacggtaaac ctgttgtcgt tcgtacaatg gatatcggtg gagataagga
    32401 acttccttac ttcgatatgc ctcacgaaat gaacccattc cttggattcc gtgctcttcg
    32461 tatctctatc tctgagactg gagatgctat gttccgcaca caaatccgtg ctcttcttcg
    32521 tgcgtctgtt cacggtcaat tgcgtatcat gttcccaatg gttgcgctct tgaaagaatt
    32581 ccgtgcagcg aaagcagtct ttgatgaaga aaaagcaaac cttcttgctg aaggtgttgc
    32641 agttgcggat aacatccaag ttggtatcat gatcgagatt cctgcagcgg ctatgcttgc
    32701 agaccaattt gctaaagaag ttgacttctt ctcaattggt acaaacgact tgatccaata
    32761 tacaatggca gcagaccgta tgaacgaaca agtttcatac ctttaccaac catacaaccc
    32821 atcaatccta cgcttgatta acaatgtgat caaagcagct cacgctgaag gtaaatgggc
    32881 tggtatgtgt ggtgagatgg ctggtgacca acaagctgtt ccacttcttg tcggaatggg
    32941 cttggatgag ttctctatgt cagcaacatc tgtacttcgt acacgcagct tgatgaagaa
    33001 actcgacaca gctaagatgg aagagtacgc aaaccgtgcc cttacagaat gctcaacaat
    33061 ggaagaagtt cttgaacttc aaaaagaata cgttaatttt gattaatcga aaagtccctg
    33121 caactcagtt acagggactt tttttgatat tttaaaaaga attttcaaga aaatctttct
    33181 tataaaaagt ccaaccttga aaaagtagtg gtcagaacaa aaaatactta aatggttcat
    33241 aaaattcttg acaagttgga gatttaggag taaactatta accagttaag taatagagag
    33301 gagtttctgc aatttagaaa tgaattgcaa ctagaaatat caaatagaaa gagagtttcg
    33361 atgaaaatta ataagaaata ccttgttggt tctgcggcag ctttgatttt aagtgtttgt
    33421 tcttacgagt tgggactgta tcaagctaga acggttaagg aaaataatcg tgtttcctat
    33481 atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga ggttagcaag
    33541 cgtgaaggaa tcaatgctga gcaaatcgtc atcaagataa cagaccaagg ctatgtcact
    33601 tcacatggcg accactatca ttattacaat ggtaaggttc cttatgatgc gattttcagt
    33661 gaagaattac tcatgaaaga tccaaactat aagctaaaag atgaggatat tgttaatgag
    33721 gtcaagggtg gatatgttat caaggtagat ggaaaatact atgtttacct taaggatgct
    33781 gcccacgcgg ataacgtccg tacaaaagag gaaatcaatc gacaaaaaca agaacatagt
    33841 caacatcgtg aaggtgggac tccaagaaac gatggtgctg ttgccttggc acgttcgcaa
    33901 ggacgctata ctacagatga tggttatatc tttaatgctt ctgatatcat agaggatact
    33961 ggtgatgctt atatcgttcc tcatggagat cattaccatt acattcctaa gaatgagtta
    34021 tcagctagcg agttggctgc tgcagaagcc ttcctatctg gtcggggaaa tctgtcaaat
    34081 tcaagaacct atcgccgaca aaatagcgat aacacttcaa gaacaaactg ggtaccttct
    34141 gtaagcaatc caggaactac aaatactaac acaagcaaca acagcaacac taacagtcaa
    34201 gcaagtcaaa gtaatgacat tgatagtctc ttgaaacagc tctacaaact gcctttgagt
    34261 caacgacatg tagaatctga tggccttgtt ttcgacccag cgcaaatcac aagtcgaaca
    34321 gctagaggtg ttgcagtgcc acacggagat cattaccact tcatccctta ctctcaaatg
    34381 tctgaattgg aagaacgaat cgctcgtatt attccccttc gttatcgttc aaaccattgg
    34441 gtaccagatt caaggccaga acaaccaagt ccacaaccga ctccggaacc tagtccaggc
    34501 ccgcaacctg caccaaatct taaaatagac tcaaattctt ctttggttag tcagctggta
    34561 cgaaaagttg gggaaggata tgtattcgaa gaaaagggca tctctcgtta tgtctttgcg
    34621 aaagatttac catctgaaac tgttaaaaat cttgaaagta agttatcaaa acaagagagt
    34681 gtttcacaca ctttaactgc taaaaaagaa aatgttgctc ctcgtgacca agaattttat
    34741 gataaagcat ataatctgtt aactgaggct cataaagcct tgtttgaaaa taagggtcgt
    34801 aattctgatt tccaagcctt agacaaatta ttagaacgct tgaatgatga atcgactaat
    34861 aaagaaaaat tggtagatga tttattggca ttcctagcac caattaccca tccagagcga
    34921 cttggcaagc caaattctca aattgagtat actgaagacg aagttcgtat tgctcaatta
    34981 gctgataagt atacaacgtc agatggttac atttttgatg aacatgatat aatcagtgat
    35041 gaaggagatg catatgtaac gcctcatatg ggccatagtc actggattgg aaaagatagc
    35101 ctttctgata aggaaaaagt tgcagctcaa gcctatacta aagaaaaagg tatcctacct
    35161 ccatctccag acgcagatgt taaagcaaat ccaactggag atagtgcagc agctatttac
    35221 aatcgtgtga aaggggaaaa acgaattcca ctcgttcgac ttccatatat ggttgagcat
    35281 acagttgagg ttaaaaacgg taatttgatt attcctcata aggatcatta ccataatatt
    35341 aaatttgctt ggtttgatga tcacacatac aaagctccaa atggctatac cttggaagat
    35401 ttgtttgcga cgattaagta ctacgtagaa caccctgacg aacgtccaca ttctaatgat
    35461 ggatggggca atgccagtga gcatgtgtta ggcaagaaag accacagtga agatccaaat
    35521 aagaacttca aagcggatga agagccagta gaggaaacac ctgctgagcc agaagtccct
    35581 caagtagaga ctgaaaaagt agaagcccaa ctcaaagaag cagaagtttt gcttgcaaaa
    35641 gtaacggatt ctagtctgaa agccaatgca acagaaactc tagctggttt acgaaataat
    35701 ttgactcttc aaattatgga taacaatagt atcatggcag aagcagaaaa attacttgcg
    35761 ttgttaaaag gaagtaatcc ttcatctgta agtaaggaaa aaataaacta atgaaaaatg
    35821 aaagtctcga taaagaggct ttcattttta ttatgtatat atgtaaaatt cttgacaagc
    35881 aatattaaaa agagtaaact attaactagt taattaaccg gtttattact ttatagtgaa
    35941 tcaaatatac ttaagaaaag aggaaagaat gaaaatcaat aaaaaatatc tagcaggttc
    36001 agtggcagtc cttgccctaa gtgtttgttc ctatgagctt ggacgttacc aagctggtca
    36061 ggataagaaa gagtctaatc gagttgctta tatagatggt gatcaggctg gtcaaaaggc
    36121 agaaaacttg acaccagatg aagtcagtaa gagggagggg atcaacgccg aacaaattgt
    36181 tatcaagatt acggatcaag gttatgtgac ctctcatgga gaccattatc attactataa
    36241 tggcaaggtt ccttatgatg ccatcatcag tgaagagctc ctcatgaaag atccgaatta
    36301 tcagttgaag gattcagaca ttgtcaatga aatcaagggt ggttatgtca ttaaggtaaa
    36361 cggtaaatac tatgtttacc ttaaggatgc agctcatgcg gataatattc ggacaaaaga
    36421 agagattaaa cgtcagaagc aggaacgcag tcataatcat aactcaagag cagataatgc
    36481 tgttgctgca gccagagccc aaggacgtta tacaacggat gatgggtata tcttcaatgc
    36541 atctgatatc attgaggaca cgggtgatgc ttatatcgtt cctcacggcg accattacca
    36601 ttacattcct aagaatgagt tatcagctag cgagttagct gctgcagaag cctattggaa
    36661 tgggaagcag ggatctcgtc cttcttcaag ttctagttat aatgcaaatc cagctcaacc
    36721 aagattgtca gagaaccaca atctgactgt cactccaact tatcatcaaa atcaagggga
    36781 aaacatttca agccttttac gtgaattgta tgctaaaccc ttatcagaac gccatgtgga
    36841 atctgatggc cttattttcg acccagcgca aatcacaagt cgaaccgcca gaggtgtagc
    36901 tgtccctcat ggtaaccatt accactttat cccttatgaa caaatgtctg aattggaaaa
    36961 acgaattgct cgtattattc cccttcgtta tcgttcaaac cattgggtac cagattcaag
    37021 accagaacaa ccaagtccac aaccgactcc agaacctagt ccaagtccgc aaccagctcc
    37081 aagcaatcca attgatgaga aattggtcaa agaagctgtt cgaaaagtag gcgatggtta
    37141 tgtctttgag gagaatggag tttctcgtta tatcccagcc aaggatcttt cagcagaaac
    37201 agcagcaggc attgatagca aactggccaa gcaggaaagt ttatctcata agctaggagc
    37261 taagaaaact gacctcccat ctagtgatag agaattttac aataaggctt atgacttact
    37321 agcaagaatt caccaagatt tacttgataa taaaggtcga caagttgatt ttgaggcttt
    37381 ggataacctg ttggaacgac tcaaggatgt c
//
LOCUS       DAVMJI010000021        36908 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.021, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000021 DAVMJI010000000
VERSION     DAVMJI010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.021"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(158..1084)
                     /locus_tag="VYR58_001242"
     CDS             complement(158..1084)
                     /locus_tag="VYR58_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622398.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVETNTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKV"
     gene            complement(1077..1769)
                     /gene="ftsE"
                     /locus_tag="VYR58_001243"
     CDS             complement(1077..1769)
                     /gene="ftsE"
                     /locus_tag="VYR58_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV3622399.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(1787..2882)
                     /gene="prfB"
                     /locus_tag="VYR58_001244"
     CDS             complement(join(1787..2809,2811..2882))
                     /gene="prfB"
                     /locus_tag="VYR58_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV3622400.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(2990..3646)
                     /locus_tag="VYR58_001245"
     CDS             complement(2990..3646)
                     /locus_tag="VYR58_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV3622401.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(4060..4770)
                     /locus_tag="VYR58_001246"
     CDS             complement(4060..4770)
                     /locus_tag="VYR58_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622402.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(4770..5534)
                     /locus_tag="VYR58_001247"
     CDS             complement(4770..5534)
                     /locus_tag="VYR58_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622403.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(5534..6490)
                     /locus_tag="VYR58_001248"
     CDS             complement(5534..6490)
                     /locus_tag="VYR58_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV3622404.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(6494..7363)
                     /locus_tag="VYR58_001249"
     CDS             complement(6494..7363)
                     /locus_tag="VYR58_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV3622405.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(7631..8791)
                     /locus_tag="VYR58_001250"
     CDS             complement(7631..8791)
                     /locus_tag="VYR58_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV3622406.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(8892..9140)
                     /locus_tag="VYR58_001251"
     CDS             complement(8892..9140)
                     /locus_tag="VYR58_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV3622407.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(9219..9809)
                     /gene="clpP"
                     /locus_tag="VYR58_001252"
     CDS             complement(9219..9809)
                     /gene="clpP"
                     /locus_tag="VYR58_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV3622408.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(9983..10612)
                     /gene="upp"
                     /locus_tag="VYR58_001253"
     CDS             complement(9983..10612)
                     /gene="upp"
                     /locus_tag="VYR58_001253"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV3622409.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(10701..11168)
                     /locus_tag="VYR58_001254"
     CDS             complement(10701..11168)
                     /locus_tag="VYR58_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV3622410.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(11187..11744)
                     /locus_tag="VYR58_001255"
     CDS             complement(11187..11744)
                     /locus_tag="VYR58_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV3622411.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            11869..12714
                     /locus_tag="VYR58_001256"
     CDS             11869..12714
                     /locus_tag="VYR58_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV3622412.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            12773..13948
                     /locus_tag="VYR58_001257"
     CDS             12773..13948
                     /locus_tag="VYR58_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV3622413.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            13968..14423
                     /locus_tag="VYR58_001258"
     CDS             13968..14423
                     /locus_tag="VYR58_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV3622414.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(14443..15114)
                     /locus_tag="VYR58_001259"
                     /pseudo
     CDS             complement(14443..15114)
                     /locus_tag="VYR58_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819367.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            15280..16755
                     /locus_tag="VYR58_001260"
     CDS             15280..16755
                     /locus_tag="VYR58_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV3622415.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMNFLVPNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKGLE"
     gene            complement(16777..17721)
                     /gene="manA"
                     /locus_tag="VYR58_001261"
     CDS             complement(16777..17721)
                     /gene="manA"
                     /locus_tag="VYR58_001261"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV3622416.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(17853..18134)
                     /locus_tag="VYR58_001262"
     CDS             complement(17853..18134)
                     /locus_tag="VYR58_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV3622417.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            18454..19455
                     /locus_tag="VYR58_001263"
                     /pseudo
     CDS             18454..19455
                     /locus_tag="VYR58_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(19572..19919)
                     /locus_tag="VYR58_001264"
     CDS             complement(19572..19919)
                     /locus_tag="VYR58_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV3622418.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(20030..21805)
                     /gene="spxB"
                     /locus_tag="VYR58_001265"
     CDS             complement(20030..21805)
                     /gene="spxB"
                     /locus_tag="VYR58_001265"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV3622419.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(22012..24255)
                     /locus_tag="VYR58_001266"
     CDS             complement(22012..24255)
                     /locus_tag="VYR58_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV3622420.1"
                     /translation="MTEIVKASLENGIQKIRIQAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSICTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDVSQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(24265..24636)
                     /locus_tag="VYR58_001267"
     CDS             complement(24265..24636)
                     /locus_tag="VYR58_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV3622421.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFSFACGMNMMHGKMIVE"
     gene            complement(24647..25042)
                     /locus_tag="VYR58_001268"
     CDS             complement(24647..25042)
                     /locus_tag="VYR58_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV3622422.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      25226..25324
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            25408..26199
                     /gene="thiD"
                     /locus_tag="VYR58_001269"
     CDS             25408..26199
                     /gene="thiD"
                     /locus_tag="VYR58_001269"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV3622423.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKVFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(26409..27041)
                     /locus_tag="VYR58_001270"
     CDS             complement(26409..27041)
                     /locus_tag="VYR58_001270"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV3622424.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(27034..27837)
                     /locus_tag="VYR58_001271"
     CDS             complement(27034..27837)
                     /locus_tag="VYR58_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV3622425.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(27837..28361)
                     /gene="thiW"
                     /locus_tag="VYR58_001272"
     CDS             complement(27837..28361)
                     /gene="thiW"
                     /locus_tag="VYR58_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV3622426.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(28366..29058)
                     /gene="tenA"
                     /locus_tag="VYR58_001273"
     CDS             complement(28366..29058)
                     /gene="tenA"
                     /locus_tag="VYR58_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV3622427.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(29069..29719)
                     /locus_tag="VYR58_001274"
     CDS             complement(29069..29719)
                     /locus_tag="VYR58_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV3622428.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(29721..31106)
                     /locus_tag="VYR58_001275"
     CDS             complement(29721..31106)
                     /locus_tag="VYR58_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622429.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLNGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(31107..31667)
                     /locus_tag="VYR58_001276"
     CDS             complement(31107..31667)
                     /locus_tag="VYR58_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV3622430.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(31929..32017)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(32226..32855)
                     /locus_tag="VYR58_001277"
     CDS             complement(32226..32855)
                     /locus_tag="VYR58_001277"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV3622431.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGVKLMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(32857..33639)
                     /gene="thiM"
                     /locus_tag="VYR58_001278"
     CDS             complement(32857..33639)
                     /gene="thiM"
                     /locus_tag="VYR58_001278"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV3622432.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALSVSPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            33720..33809
                     /locus_tag="VYR58_001279"
                     /pseudo
     CDS             33720..33809
                     /locus_tag="VYR58_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(33921..34589)
                     /locus_tag="VYR58_001280"
     CDS             complement(33921..34589)
                     /locus_tag="VYR58_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV3622433.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFEEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(34805..34893)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(35147..36283)
                     /gene="lctO"
                     /locus_tag="VYR58_001281"
     CDS             complement(35147..36283)
                     /gene="lctO"
                     /locus_tag="VYR58_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV3622434.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
BASE COUNT        10915 a         8044 c         6836 g        11113 t
ORIGIN      
        1 atttctagtg cgccaaattt caagttcaaa ttagccatca agaagtcttc tctgggggac
       61 ttctttggaa gctcttttct tctgcgcatc tcttttcaaa aactcttgta gcaaaaaagg
      121 agattttaca atctcctcat aaaagcagct attttaccta aaccttcaag aatcggcgca
      181 tggatattcc tgatcccaat gaaccaatga aaaccccaat cacaaatagt agggcaatca
      241 tcaacggact aaataaatct ggactaatca tggatagatt ttgccctacc aacgatttgt
      301 tgacagattg gtaaacaatt tgataaacaa taaagaccaa aacagatggt gcgatagctc
      361 ccaataaacc gataaaggct ccttctaaca agaacggtcc acggatataa ctgtttttag
      421 ctccgaccaa gcgcatgatt tgaatttcgc gactgcggga aataatggta atacgaatgg
      481 tatttgaaat caagaaaact gcgataaaaa ttaacaaagc agcaatccct agtccccaaa
      541 cacggataaa tgaagctaac ttgaagagtc tttctgtatt ggcaccgcca tcttgaacct
      601 cagagacacc ttcaattttt ttagcatctt cggctatagt ttttacatca tttggagtgt
      661 ttgtctctac aatataggca tcatagagag gattggcatc tccttcaaag attttccagt
      721 tatctcccat tatctcggtt aatttttcat attgttcttc tttacttgaa aaggtaacac
      781 ttttaaccgt agacatgttc ttcaaagaat catatacctt gtggtagtca ttatttgtaa
      841 cagtttgacc ttctttttca attgtctgac tattatcttc cacatccttt cggatataaa
      901 ctactacacg gacattattt tcaatatctg tagctagttt cgctgtattg aaaataacag
      961 atgcaaatat tgccaccaag gtcaaagtaa tcatgactga actgacagca gctactgtca
     1021 tccaaccatt tcgtttcaaa ctttttaagg cttcaaataa atggcgaaaa aatctactaa
     1081 tcatcgtatc catactctcc ttttgattcg tcacgaacga cacggccatt ttcaatggca
     1141 atgacacggt ggcgcaaggt atttacaatc tggctattat gagtcgccat caaaatagtt
     1201 gttccttgta ggttaatccg ttccaaaaga ttcataattt cccatgaatt atccggatcc
     1261 agatttcctg ttggctcatc agctatcaat actttgggat tatttacaat tgcacgcgca
     1321 atcgcaatcc gctgttgctc cccacctgag agttcatttg ggaaagaacg aaccttatgc
     1381 ttcaatccaa ccaagtccaa aacttccatc actcgtcttt tgatattacg gcgattttcc
     1441 ccgattactt ccatagcgta agcaatattt tcatagacag ttttctttgg taacaattta
     1501 taatcctgga agacaacccc aacactacga cgtagaagcg ggatatcttt ctttttgatc
     1561 ttaaccagat taaaaccagc aactgatagg cttcctttat cgatttttac ttcacgatac
     1621 agagaacgaa taaaagttga cttccctgct cctgaaggtc ctacgatgta agcaaattcc
     1681 cccggttgaa cgctaaccga aacaccgcgt agagcagtcg ttccgttgtc gtatttttta
     1741 acgacatctc tcatttcaat aattgacatg tgagttcctt tctatcttag ctaattcgcc
     1801 acttgagata agcatcgata aaaccatcta agtccccatc cataacctta tctacctgag
     1861 caacctcaaa gctagttcgg tgatctttta ccatagtata aggcgtgaag acataagaac
     1921 ggatttggct tccccaagtg atctcctttt tctcaccttt gagagaatct acctctgcag
     1981 ccttcttctc ttgctccatt tgatagagct tagcctgcaa catcttcatg gcacgatctc
     2041 tatttccata ctgggtacga tccactgttg attggacaac aattccagtt ggaatgtggg
     2101 ttaaacgtac acctgttgaa accttattga cgttttgtcc accggcacca cctgaacgga
     2161 aggtatccat cttgatatca tcttcacgga tttccacttc aatagtatca tccaattctg
     2221 gcatcacttc tacagatgtg aaagaggtat ggcgacgttt ggcagagtca aatggtgaga
     2281 ttcgcactaa gcggtgaaca cccatttctg acttgaggag accataggca ttaggccctt
     2341 caaatgataa agttaccgac ttaataccag cctcatcacc tgcttggtaa tccaacactt
     2401 ccactttaaa gcctttagca ttaccataac gagtatacat acgaagcaac atatcacccc
     2461 agtcctgcgc ctcagtacca ccagaacctg gatggatttc caagatggca ttgttgtggt
     2521 cataaggttc tgacaagagt agagtcatct cgtagctggt cattatctta tcaagttcgg
     2581 ctaactgcgc taccagttca tcatgcactg actcgtcttc agccaaaaaa tccaataaaa
     2641 tttcgacttc atcctgcaac tcttccatct tatggaaggt attgtaagtg ttttttaatt
     2701 catttaattc ttgcgacgtt ttttgggctg caatattatc gttccaaaaa tcaggttctg
     2761 tcatcttgtt ttccaagatg gcaatctctt cctctagccc ttcgaggtca aagagacccc
     2821 ctgaaagaag ctaatttttc acgatttgcg tcaattttct gacgaattac tgaaatgtcc
     2881 ataaatactc cttttttaca ttatttcatt atagcatatt ttatcatttc tttccatctt
     2941 tttctctaat ccccttttca tgaaaaaaga agcctttggg cttcccttct tacaagactt
     3001 ttgctgaagt gcgagcgatt tcttccactt gaataccatt tgcttcaaat ttttctttca
     3061 aggctggtaa atcaattgat ccatcgattt gcacttcgat aatcacctta ccatccttac
     3121 gcggaatatt gactgtatgg gagatattca aattttcttc tacaatcaaa gaaacaattt
     3181 ttccaagaac accaacttca tcttctgtaa caaagcgtac acgaatccct tcttcgccat
     3241 aacctgcaat ttcaagaaag gcttggaaaa cgtcacggtc agtaataact ccgtatactt
     3301 gatggttatc tacgacaggg agaatactaa tcttattttt caacatcaga taagttgcat
     3361 cttctagact agcatagcct gagacagtga caacatcgcg aatcatgaca tcttttactt
     3421 ttgtcttatt cagaagataa ttcatctcat agatagaaag acttgttgct ttagatggac
     3481 ttgcttgtgc aatggttccc tcagtcacca aaccaactaa ttgatcattt tcgataacag
     3541 gcagacggtg caaaccttgc tctctcatca aatctgctgc atgagatact gttgtatctg
     3601 gactaatata aactaccttg cgggtcataa aatctttaac tgccatgaga cttctccttt
     3661 tctattctta tccctattat acaatctttt tgtaaatcta tcaaacgctt acatttcttt
     3721 ttcgaaattc agaaaagtat gaataagcta gcaaaaagag ctctgaaatc gagctctgtg
     3781 aatgaaggta agaaattttt cattcgattt tttcaattat tagaaattaa gctttcaatg
     3841 tagatgcaga tttgtttgca atctcaatct accgactaaa aaggtccccc ggactatatt
     3901 gatgattact tcgtaatctc catctgccga ctaaaacaat ccactggatt tgatgattgc
     3961 ttcgcaatct ttatctgcaa cctaaactag tctcccagac tataatgatg attacttcgt
     4021 aatcttcatc tgccgactaa aacaatccac tggattgttt tagccaccta gatatgcttt
     4081 tctgacttct tctgatgagg cgagttcttt tcctgttcct gataggacga ttttccctgt
     4141 ttccagtaca tatcctcggt cagagattgc aagtgcttta ttggcatttt gttcaatcaa
     4201 gaggacggtt gttccttgct tctgaatatc ttgaatgata tcaaaaatct cttggatgaa
     4261 gattggggca agtcccattg atggttcatc taaaagaaga agttttggtg ttgacataag
     4321 agcgcgtccc atggcaagca tttgttgttc ccctcctgaa agagtagctg catcttggtt
     4381 cttacgttct tcaagacgag gaaagcgtga gaaaaccttc ttcaagttag cttgattttc
     4441 ttcacgattt ttctttaaga aagctcccat ttcaagattt tccataacag tcaagccagg
     4501 aaagacgtgg cgtccttctg gaacttgtga aagaccacct gccacaattt tctgagctgg
     4561 cattttttgg atttcttgac ctaaaaattc aatctttcct gaacttggtc gaaccaaacc
     4621 tgacaatgtg cgaagaatag ttgtcttacc tgcaccgttg gcaccgataa gggaaacaac
     4681 ttctccttca ttaacttcaa agcttacatc acggactgct tggatcatac cgtaatgcac
     4741 agaaagattt tcaactttta acatagacat taggcttcac ctcctagata agcttcgata
     4801 acgcgtttat tggtcttaat ttcgtctgga gttccttgag caattaaacg gccatattca
     4861 agtacgtaga tacgttctgt tacttccatg accagattca tatcgtgttc aatcaacatg
     4921 attgtaatct taaattcatc tttgatacga cgaattaact cagtcaattc ggctgtttcc
     4981 tgtgggttca tacctgctgc tggttcatct aagaagagaa ttttaggttc cgtagcaagg
     5041 gcacgaacaa tttccaaacg acgttgttgt ccgtaggaaa gatttttagc aagagtctct
     5101 gcatcaccat ctaaatcaaa gattttcaac aattccaaag ctttagcctt taattctttt
     5161 tcactcttgt aaaaagctgg taagcgtaag aaactagtaa aaacatgttg tttgtgatgg
     5221 tttccaaaag caatcaaaac attgtctaaa actgttaaat ctttaaagag acggatattt
     5281 tggaaagtac gtccaagtcc caaagaggca atcttataag gtgatttccc attcaaaagg
     5341 tgaccatcta gggttactgt tccctcgctt ggttcataaa caccggtcaa aaggttgaaa
     5401 agggtggttt tcccagctcc gtttggaccg attaatccaa ccagttcccc ttcgttcaat
     5461 tcaagagtca catctccaac agctgttaga ccaccaaaat gtttggttaa ctgttttact
     5521 tcaagtaatg ccattagttt tgttcctcct tcttagattt tttaaagaaa cgtgataggc
     5581 tcagttccca tgttccaagg agtccacctg gtctgaaaat cattaccaat accaaggcca
     5641 aagcgtaaat aatcatacgc acactagcaa catcttggag aagcatattc aaaattccca
     5701 gaacaatagc cgaaacaatc gcacctgtaa tggaaccgag tccaccaaat acaacaataa
     5761 tcaaaacgtt gattgagttg atgaaggtgt aatctttcgg tacaacagac ccgataaatc
     5821 ctgcctgaag tgacccagca atacttgcag taatggcacc aaagacaaaa gcgatgattt
     5881 taattttagt cgtattaacc ccaactgact cagcagcgat ttcatcttca cgaacagaga
     5941 gggttgaacg accaattggg ctacgcaaga agttcaaggt tgcaatggtt gtaatcacga
     6001 caaagaagta aaccatttgc caagttgtaa agttaggaat ccctaagata cctgccgcac
     6061 catttgtaag gcttccacca ttgatgataa agatacggat aatttcagaa acacccagag
     6121 ttgctaccgc aagatagtcc cccttcaagc gcaaggttgg aatgccgaca agtaaggcaa
     6181 ctgctcctga aagcaaagcc cctacaagca tagctccaaa gaaggcaccg taggttggta
     6241 atttagaacc aataatagct gctgcatagg caccaatcgc catgaaacca gcatgaccaa
     6301 gtgaaaattg tcctgaaaaa ccaacgatta agttgagacc aacagccaaa ataatattaa
     6361 ttccaatttg ctgtaaaatc tgtacataga atagattaag tactccgact gaaaccagta
     6421 cactaatcaa gctatagcca gctaacaaaa ggagtaacca tagaatatta acttttaaat
     6481 tttccttcat cgtttacacc ttctctttca cattcttacc aaggatacca gctgggcgga
     6541 caatcaagat caacaacaag attccataaa caatggcatc acggaaatct gacatcccaa
     6601 aggcagtcgc aaaggtttcc aatagaccaa tcacaaagcc accaagagcc gcaccaggaa
     6661 taattccgat accaccaagt actgcggcaa cgaaagattt aagacctgga gtaaccccca
     6721 tcaaaggctc aagagagtta taataaagag caatcagaac accagccgca cccgcaagag
     6781 cagaacccaa agcgaaggta aagctaatcg tacggtttac attgatcccc atcaattgcg
     6841 ccgcgtcgct atctactgat actgcacgca tggctttccc catcttagtc ttttggacaa
     6901 tgacttgtaa caaaatcatc aaaatcaagg aaatagccaa aatcattaac tgcacatttg
     6961 ttaagctaat tggtcccaaa tcatatcgaa ctgtttgaat cgcttgaggg aaggcacggg
     7021 tattggcacc aaccagatag accattccat actccaatag gaaagaaacc ccaatagccg
     7081 taatcaaaac agcaatacga gtagagtggc gcaaaggtcg gtaagcaaga aactcaatca
     7141 cgacaccaag aatagctgtc gctagcatag ctacaataag cgctacaaag aaattcattt
     7201 ggaaagaatt gatcaagaaa taaccgataa aggctcccat catataaata tcaccatggg
     7261 cgaagttgat gagcttgata attccgtaaa ccatggtata tcctagggct aacagcgcgt
     7321 aaacactacc tagaatcaaa ccatttacga gttgttggag cataagattc actctttcta
     7381 tttataattc cgaggggttt ccctcacttt ttgataggtt cttatactca atgaaaatca
     7441 aagagcaaac taggaaacta gccgcaggtt gctcaaagca ctgctttgag gttgtagata
     7501 agactgacga agtcagtcac atatataatc caaggcgacg ttgacgcagt ttgaagagat
     7561 tttcgaagag tattaaatat cgaaacaggg agtgagtcaa aggctcattc cctatttcaa
     7621 catttttcta ttatggtttt acaacttctg ctgcttcaac tttaccattg ttcatggtca
     7681 tcatgtaagc agttttgact gtgttgtggt ctgcatcgaa gcttgtttga ccagttacac
     7741 cttcaaaatc ttttgtttta gcaaggttat ccttgatttc acctgaattt ttagcacctt
     7801 ttgctgcgtt tgctacaagg tgaactgaat cataagccaa ggctgcaaat gttgaaggct
     7861 cttcattgta cttagcacgg taagcgtcaa ggaaggcttt agctttagct gaaacttcta
     7921 cagtagttga gaagcctgag ataaagtaga tgtttgatgc tttttcagca gttgcttgtt
     7981 gtacaaactc ctcaccgttg aatccatcac caccaacgat tggtttgtca attcccatac
     8041 cacgcgcttg gtttacaatc ttaccagcct cattatagta accaggaaca acgatagcat
     8101 caaagtcttt ccctttcatt tttgtaaggg ctgcttggaa gtctgtgtca cctgctacga
     8161 aagtttcatc tgcaacgatt tcacccttgt atgactcgcg gaaagatttg gcaatccctt
     8221 tagcatagtc actggcattg tcagtgtaaa gaacaacttt cttagcattt aatttttcag
     8281 aaacatagtt tgagataatt tttccttgga agctatcttg gaaagttcca ataaagaggt
     8341 aatcttgacc tttagtcaat ccatcttgag tcgcacttgg tgagatcaag ggaacacctg
     8401 cttttgtagc gttcgctacc gcagctgcag tcgcaccaga tgttgcaggt cctacgactg
     8461 ctgatacttt agattgggtt acaaggttag ttgtaactga agcagcctca gctgtttcag
     8521 acttattatc tttatcgact acttcgattt gttttccatc gataccacct gcggcattga
     8581 tttcatcaac agccaattgg gcaccttttt gttcagctgt tccgtatgca gctaaagaac
     8641 ctgattcttc aaagttaaac ccgattttaa ttgtcttttc ctctactgag ttaccagcag
     8701 tgttgactgc tccagacttc acttctccac aggctgcaag aagtgctaca cttgcaagcg
     8761 ccacaaacga tagggcaaat tttttcttca tctttttgtc tccttatttc ttaaatagtc
     8821 tgttaagaat ataccgaatt atcagaaaat tgtcaatgtt ttccttgaac tttttcgatg
     8881 ataacgtttt cctatcgata aagattgccc acaaagggtg tttccaactc ttggatatga
     8941 caaaccctaa cttttttaat aaatttttcc ttgctcaagc gtccgaccaa ttgctccact
     9001 tcttgagttg gaacatagag ttgtaagtaa cgatgtttct tggaatgata ggtaatatct
     9061 ccataatcct gcagtttttt ggcatcacga ttatagtaaa gatagataat caagccagag
     9121 cgattgactt tttcaaacat gataaatcct ctttctaaga aatctctccc tattatacca
     9181 aaaaaagcaa acccagtcga gtttgccttc tatcatcatt agttcaatga attgttggcc
     9241 ataatttcat caataaagcc atattcaagt gtttcctggg cgctcatcca gttatcacgt
     9301 tctgcatctg catggacttt ttccattgac tgacctgaat tttcagccaa gattttttcc
     9361 aaggtattac gagttttgag caagtgttct gcagcgatag ccatatcagt ttgttgggta
     9421 ccaccacctg taccgcccat tggttggtga atcatgtatt cagcatttgg aagcatgaaa
     9481 cgtttgcctt ttgctccact tgatgcgatg actgttccca tagatgcagc cattcccata
     9541 acaatggttt ggacatctgc cttgataaag ttcatggtat ctacgattgc caaaccagct
     9601 gaaacagaac cacctggtgt attgacataa aggtaaatat cttttgtact atcttgggca
     9661 tccaagaaaa gcaattgggc aataacagag ttagccatat tgtcttcaac cggacctgtc
     9721 agcataatga tgcggtcttt gagaagacgt gagtaaatat cgtaagaacg ttctccacgg
     9781 cttgtttgtt caataactac aggaatcatt catttctcct tttgagtttt aattttgttg
     9841 gtcaaatgac tgaagataag actattataa tatcttggtc aaaaaaggtc aaatttttgc
     9901 tctgctttca ttagacagaa acaaaaaccc aacctccttt cgtgactgga aatacttttc
     9961 caagtcattc ttcttttcga tcttattttg taccgaacaa gcggtctcca gcatctccaa
    10021 gacctggaac gatataaccg tgttcgttca aacgttcatc caaggctgct gtaaagattt
    10081 ctacatctgg atgagcttct tgaagggctt ttacaccctc tggagcagat acaaggcaga
    10141 caaatttgat atttgatgcg ccacgttttt taagagaatc aacagccaag attgctgagc
    10201 cacctgttgc caacattggg tctactataa aaatttgacg ttggtcaatg tcctcaggca
    10261 atttcaccaa gtattcaact ggttgaagtg tttcttcatc acggtacata ccgatgtggc
    10321 caactttagc agctggaacc aagctcaaga gaccatcaac catcccgata cctgcacgca
    10381 agattgggac gatggccaat ttcttacctg ccaattgttt ttgaactgtt tttgtaattg
    10441 gtgtttcgat ttccacatct tctagtggaa gatcacgaag tacttcatac cccatcaaca
    10501 ttgcaatctc atctactagc tcacgaaaag cttttgtaga agtatctgta cgacgcaaga
    10561 ttgacaattt gtgttgaatc agtgggtgat taataacttc aatttttccc atttttggaa
    10621 ttccttcttt caatttattc ttcttattat accaaaaaac ggtttaaaaa tctttctaag
    10681 ccatttattt ttgataattt ttacattaga tcagcctctt taagagctgt ctgtactgtc
    10741 tcaagtggta aatgggtcaa ttctgtccct ttttcttgat aaaggtattg ggcgtagtcg
    10801 tccattcggt actggttgat ataaaccacg cgcttgcagc cgacctgaag caattgtttt
    10861 gtacagttga gacaaggaaa atgggttaca taggctgtaa agcctttggg aacaccacgc
    10921 tcagcacctt gaaggatagc attgacctca gcgtgaaggg tgcgaacaca gtggccttca
    10981 atgaccaaac attcgtgatc aatacaatgc tcagtccctg acaccgaacc attgtaacca
    11041 gtggaaataa ccttattatc ttttaccaga atcgcgccca ctttagcacg tttacaagtg
    11101 gaacgattcg caattagtag ggcttgggct gcaaaatact catcccaggc cagtcttttt
    11161 tcagtcatct cttttctcct ttttctctat tttttaaaaa atggtaaacc taaatctgca
    11221 atcttttcag ctggtacctt catgccatcc ttgatccatt ttagaaggac agagacgatg
    11281 gctgagctcc agaaggaatg aagataagag ctgacacctt ttgatttccc atggtatttt
    11341 tctagaaatt cctgcatggc ttggacaaag attttttcca gatggtaatc caaggccaat
    11401 tgaatcactc tagcttcctt tctggcctcc cggaaaaggt gaacccaaac caaataaagg
    11461 tctgtcttta aatcgtaatg atgcagctgt tccataatat tgtggacagt tcgtttaaag
    11521 acgctctcta aaatttcctc tttggagtca taattgcgat aaaaggccgc acgcgaaaca
    11581 cctgcacgtt tgaccaattc agaaatacta atcttggtca gctccttttt ttccaagagt
    11641 tgcaagaggg ctgtttcaat ggcttctctg gttaataaat tggattcttg gtttgatttt
    11701 ctgagatttt caagagactt ttcagagatt ctacgttcag acataacatt ttctttctac
    11761 ttgtcacaac agacggatga tgcttttgtt tcaagggttt tcatgatata attgtaaaaa
    11821 aagacagaac ctttgtcaat gtataactga caaagatgga gaatttctat gacttggaaa
    11881 attattgctg actctggttg tgattatcgt caactgccaa caccagctat taacacaacc
    11941 tttgtaagtg tccccttaac cattcaagta gctgatcagg tctttgttga tgacgccagt
    12001 ctcgatattg accaaatgat ggaaaccatg tatgcaactg cagaagcttc aaaatcggct
    12061 tgtccaagcc cagatgacta tttgcgagca tttgaaggtg ccaaaaacat tttcctagta
    12121 accatcacag gtaccctttc tggcagtcac aatagtgctc aactagcaaa gaatatttat
    12181 ctagaagacc atcctgacac taagattcat gtgattgata gtttatctgc tggtggtgaa
    12241 gttgacctac tcgtagaaaa attgaatgac ttgattgacc agggcttgtc ttttgaagaa
    12301 gtggttgaag ctatcactgc ctatcaagaa aaaactaagt tgctctttgt cctagccaaa
    12361 gtcgataact tggtgaagaa cggccgtttg agcaagctta tcggtacggt cgttggcctt
    12421 ctcaacattc gtatggtcgg aaaagctagt gaaactggaa ctctcgaatt gctacaaaaa
    12481 gcaaggggat caaagaaatc agttcaagct gcctatgatg agttagtaaa agctggatat
    12541 gctggtggcc gtattgtcat ggcccaacgc aataacgaaa aatgttgtca acagctctca
    12601 gagcgaatcc gtgaaacctt cccacaagcg gatattaaaa ttctaccaac ctctggtctc
    12661 tgcagtttct atgcagaaga gggcggtttg ctgatgggct atgaaattga ttaattgcat
    12721 tcttgacaag aggtgaccat catctcttgt ttttttgtgg tacaatagag ctatgaaaca
    12781 ttttgatact attgtcatcg gtgggggacc tgctggtatg atggctacga tttccagtag
    12841 cttttatgga cagaaaaccc tcctcatcga aaaaaatcgg aaacttggaa aaaaattagc
    12901 tgggactggt gggggacgtt gcaatgtgac caacaatggt agcttagaca acctgctagc
    12961 tggaattcct ggaaacggac gctttcttta cagtgttttc tcccagttcg ataatcatga
    13021 catcatcaac ttttttacag aaaatggtgt taaacttaag gtcgaagacc acggacgcgt
    13081 ctttccagcc agtgacaagt ctcggactat tatcgaagct ttggaaaaga aaatcaccga
    13141 actaggtggt caagttgcta ctcaaataga aatcgtttct gttaaaaaag tagatgacca
    13201 gtttgtcctt aagtcagcgg atcaaacctt cacttgtgag aaactcattg tcacaacagg
    13261 tggtaagtct tatccttcga ctggttcgac tggttttggt cacgagattg ctcgccattt
    13321 taagcatacc atcaccgatc ttgaggctgc tgaaagtcct ttattaacag attttccaca
    13381 taaagcctta caagggattt ctctggacga tgtgacccta agttatggta agcatgtcat
    13441 cactcatgat ttactcttta cccactttgg tttgtcaggt cctgctgccc tacgcatgtc
    13501 tagctttgtc aaaggtgggg aggttctctc actcgatgtt ttgcctcaac tttctgagaa
    13561 ggacttggtt acatttctag aagaaaatcg ggaaaaatcc ttgaaaaacg ctttaaaaac
    13621 cttgttacca gaacgcttgg ccgaattttt tgtacaagga tatcctgaaa aagtcaaaca
    13681 actgactgaa aaggaacgag aacaacttgt ccagtccatt aaagaactta aaattcctgt
    13741 aactggaaaa atgtcccttg caaagtcctt tgttaccaag ggtggagtca gtctcaagga
    13801 aatcaatcct aaaacccttg aaagtaagct ggtacctggc ctccactttg caggcgaagt
    13861 tatggatatc aatgcccaca cgggtggctt taacatcact tctgccctct gtaccggctg
    13921 ggtggcggga agtctgcatt atgattaaag attaaaggtt gtgaagaatg aacagaagag
    13981 aggcagtcga atttgttaac atgtgtatga ttaaaaacgg agataaggtc ctggtccaag
    14041 accgagttag tcccgactgg tctggcatta cttttcctgg tggtcatgtt gaacgtggcg
    14101 aatcctttgt cgatgctgtc attcgtgaag tgaaagaaga aactggtctg atcatttcca
    14161 aaccccaact ctgtggtatc aaaaactggt atgacgacaa ggattatcgt tatgtcgtcc
    14221 ttttttacaa gacagaacac tttactggtg aactccagtc ttcagacgaa gggaaagttt
    14281 ggtgggagga ctttgaaaat ctttctcatc taaaacttgc aaccgatgat atgtctgata
    14341 tgcttcgtgt gtttctagaa gaagatctca gtgaattctt ttactacaaa aacggtgacg
    14401 actggcttta tgatttgaag taaaaaatag gctaggaaat tcctagccta ttttttctgc
    14461 atttgtctga acgtaagccg caatggcatc tgacgtgtac tgggctgttt cagaaccaaa
    14521 cttgtcaatg ttttccttaa actctgggtt gtagacgtaa cctttaccga tatgaccgaa
    14581 tacctcaata gagcagtcaa atccataagt gcgaatggct tgcaagagct tggctgcttg
    14641 ctcctggttt tcggttgctg ttgcaggtaa accaacttga agattttgtg ccaaagtttg
    14701 aaagacttgg ttaaaggcgg ccgtagcctc gtcttcgtga cctttttggc gttcgagcgc
    14761 ttgtcccatg acttcttgac catatttctc taccgcttct tggtggtatt tttgattgtt
    14821 ttgatagcta aatcccgtga atttttcctc aatggtcatt tttctttctc ctttttgttc
    14881 ttgaatagtt ttttgcaagg tggaaatcaa ggtatccaga tgttgccttt cgcgagttag
    14941 atagtccaac tacctagtca aatggagcaa taaatctgtc ctttcttcct ttaacagttc
    15001 tgctattttc tctaaagaaa agcctagata tttgtagtaa agaatgacct gaaggcgttc
    15061 caaatcctct tgactatagg ttcgatagcc gttttccgac tttaagggga ccaagagtcc
    15121 tatcttgtca tagtgatgca gggcagggtc ttgacagaga cacctgaaag ctgcgcagct
    15181 tcttttatat ggtacatgat ttcctcctta caatgatagt ataacccctc cccttaggtc
    15241 agagtcaagc gtttttgaga aaggtgtgaa aacttgaaaa tggttttctt gacagacctt
    15301 agaaaacata ataggatagt caagtctatc aatcaaacag aaggctattt gacaactcaa
    15361 gtagcttttt cttattttga aaaaggagat cagagtttaa ctatgtcaga aaaatcacaa
    15421 tgggggtcga aacttggctt tattctagca tctgctggct cggtcatcgg gcttggttcc
    15481 gtttggaagt ttccctacat gactgctgct aatggcggtg gaggcttttt actaatcttt
    15541 ctcatttcca ctattttaat cggtttccct ctcctgctgg ctgagtttgc ccttggccgt
    15601 agtgctggcg tttccgctat caaaaccttt ggaaaactgg gcaagaataa caagtacaac
    15661 tttatcggtt ggattggcgc ctttgccctc tttatcctct tatcttttta cagtgttatc
    15721 ggaggatgga ttctagtcta tctaggtatt gagtttggga aattgttcca acttggtgga
    15781 acgggtgatt atgctcagtt atttacttca atcatttcaa atccagccat tgccctagga
    15841 gctcaagcag cctttatctt attaaatatc tttattgtat cacgtggggt tcaaaaaggg
    15901 attgaaagag cttcgaaagt catgatgccc ctgctcttta tcatctttgt tgttatcatc
    15961 ggtcgctctc tcagtttgcc aaatgccatg gaaggggttc tttacttcct caaaccagac
    16021 ttttcaaaac tgactagcgc tggtctcctc tatgctctgg gacaatcttt ctttgccctc
    16081 tcactagggg ttacagtcat gttgacctat gcttcttact tggacaagaa aaccaatcta
    16141 gtccagtcag gaatctccat cgtagccatg aatatctcga tatccatcat ggcaggtcta
    16201 gccattttcc aagctcggtc ccccttcaat atccagtctg aagggggacc gagcttgctc
    16261 tttatcgtct tgcctcaact ctttgacaag atgccttttg gaaccatttt ctacgtcctc
    16321 ttcctctttg cgactgtcac ttcttctgtc gtgatgctgg agatcaatgt gggcaatatc
    16381 accaaccagg ataacagcaa acgtgccaaa tggagtgtta ttttaggaat tttgaccttt
    16441 gtctttggca ttccttcagc cctatcttac ggtgtcatgg cggatgttca catttttggt
    16501 aagaccttct ttgacgctat gaacttcttg gttcccaatc tcctcatgcc atttggagct
    16561 ctctaccttt cactttttac aggctatatc tttaaaaagg ctcttgcaat ggaggaactc
    16621 catctcgatg aaagagcatg gaaacaagga ctgttccaag tctggctctt ccttcttcgt
    16681 ttcttcgttc cgtcattcca atcatcatcg tggtcttcat cgcccaattt atgtaatcaa
    16741 aaaggacttg agtaatgaac tcaggccctt tcttttttat ggatgactaa caattaattc
    16801 taaatcttgc ccttccagag tccaagcttc aacatcactt ggtaggataa agtgtctccc
    16861 tttttggatt ggatagtttt tcccgtcaac agttagttga ccttgaccag ccaagacact
    16921 caacaagctg tagtcagctg tcttttcaaa gttaactttt ccagtaattt cccatttgta
    16981 aactgcgaag aaatcattgg atacaaggag agtggaacgt agatcatctg ctttgattgt
    17041 cactggacgg ctatttgcgg gttcaccaat gttcaagaca tcgatagatt tttcaaggtg
    17101 aagttcacgt aaattgccct tgtcatcctt acggtcaaag tcatagacac ggtaagtggt
    17161 atcgctagac tgctgggttt caagaatcaa gatacccgcc ccgatagcgt gcatggtacc
    17221 gcttggtaca tagaagaaat ctcctgcttt aactggcact tttgtcaaca gcgcatccca
    17281 gttcttatcc tcgatttgct ggcggagttc ttcttttgac ttggcattgt ggccgtagat
    17341 aatctctgaa ccttcatccg cagcgatgat gtaccagcat tctgtttttc caagttcgcc
    17401 ttcatgctct agtccataag catcgtctgg gtgaacttga acgctgagcc agtcgttagc
    17461 atccaaaatc ttagtcaaaa gcggaaatac aggctcagga cgattgccaa ataattcacg
    17521 gtgttccgca tacaaagtag caagatctgt tccctcgtaa cgaccattgg caactttaga
    17581 aacaccattt agatgagctg agatagccca gtactctccg actttttcac ttgggatgtc
    17641 gtagccaaac tcatcacgta gcttggtacc accccagatt ttttcttgca taactgattg
    17701 taaaaataat ggttctgaca tcttaatctc ctgtctgatt tttctcccct cattatagca
    17761 aaaaaagagt tcgaattgaa ctctttttta catcttataa agcagggaga agattttata
    17821 aaaatagtaa acaaatgtgc tctactcgat gcttacacca ttgctataaa tgacatgtac
    17881 caatagaagg acttcttctt gctacgtttg agagtcccat ttcctacatt atctcgatct
    17941 acatagataa agccatagcg cttattcatt tcccctgtgc cagctgaaac cgaatcgata
    18001 cagccccatg tcgtataacc aagcaagtca accccgtctt tgtaaatggc atctcgcatg
    18061 gccttgatgt gggcctctaa gtaagtaatc cgatagtcat ctgctacata accattctca
    18121 tccggtgtat ccatagcacc gagtccattt tctacgataa tactatacta aaatcaaaaa
    18181 gcattatata atagtgatat gaaatcaact aaagaagaaa tccaaaccat caaaacactt
    18241 tttaaagact ctcgtacagc taaatatcat aaacgccttc aaatcgttct atagtaaaac
    18301 gaaacaagaa cagggcaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    18361 agtagaggtg tactattcta gtttcaattt attatatttc gtctgatggg caaatcttat
    18421 aaagagatta tagaactttt atagtagttt gaaataagat gtgaacaact ctatcaggaa
    18481 agtcaaacta atttatagaa atattttagc agataaggtg tactgttata gattcaatac
    18541 actatagact gtaatcaaac aacgatttgg cgaaatgtaa aaaaatatga ggagttcgaa
    18601 ctcgactctc tccttcaaga aacacgtggt ggccgtaacc atgcatatat gacgattgag
    18661 gaaaagaaag tctttcttgc ccgccatttg aaggctacag aggcaggaga atttgttaca
    18721 attgatgcct tatttcaggc ttataaaaag gagttaggtc gttcctacac acgtgatgcc
    18781 ttctatcaac tgttgaagca ccatggttgg cgaaatatta tgccacgtcc agaacatcct
    18841 aggaaagcag acgctcaaac cattgtcgcg tctaaaaata aaatctcaat tcaagaagaa
    18901 aagaaagcgc tttaaaagca gtagacgttt tcgtaaggtt cgcttgatgt accaagatga
    18961 ggctggtttc ggtagaatca gtaaactggg atcttgttgg gctccaatag gagtaggtcc
    19021 acatgtccat agtcactata tacgagaatt tcactattgt tatggagctg ttgatgccca
    19081 tacaggcgaa tcatttttct taatagctgg tggatgtaat actgagtgga tgaacgcctt
    19141 tttagaagag ctttcacaag cttatccaga tgattatctt ttactcgtta tggacaatgc
    19201 tatatggcat aaatcaagta ccttaaagat tccgactaat attggtttta cctttattcc
    19261 tccatacaca ccagagatga acccattgaa caagtgtgga aagagattcg taaacgtgga
    19321 tttaagaata aggcctttcg aactttggaa gatgtcatga atcaacttca agatgtcata
    19381 caaggactgg agaaggaggt gataaagtcc atcgttaatc ggagatggac tagaatgctt
    19441 tttgaaagca tatgagtatt atatgcaatt tctttatata aaaagaccgg attgctccga
    19501 tctttcaata gttcatattc tcaatttcta ttttaaaaat agctaaggtt aacgtcaaat
    19561 gactacgcga cctatttcat acgataaaaa tcaagcacta gaccagcagg tccttgaact
    19621 aataaggact ctgttcccca atcggttaca gttggtccgt gtaaaacctt tataccaagc
    19681 tcgttcaacc gtttgtagtt ctggtctaca tcctcaacct cgatatgaat aatgattcct
    19741 gactgaaagt tttccaaagg aaccaaatga ttttgtgaca acataaggca gtgactacca
    19801 atcgtaaact gagcaaaacc atcatcagca taatctgcct ttttatccaa aatatgctcc
    19861 aagtcagcac agacttgggg aacatttgaa acgataatat ctaattgatt taaattcatt
    19921 tactctcctc cataaaaaga ccggattgct ccgatctttt aaagttctgc tctatgaaaa
    19981 tcaaagaata aagtctacaa gtttcatatt tgattttcgg cgagaggaat tatttaattg
    20041 cgcgtgattg caatccttct tcttccaaga agagacggaa tggtacgagt tcttctgctt
    20101 cgtatttttc cttgaaggct ttgatagctt cttctgagtg aagttttgga tccaattcaa
    20161 gtacttctac tggaagtgga cggtgttgag tgatgcgagc atcgatgaca acagttttac
    20221 cttctttgtt caatttaaca gcttctgcaa caactgcatc gatgtcttcg atacggtcaa
    20281 ctgtgaatcc aacagctcct tgagcttccg caattttagc gtagtcagcg tttgtgaagt
    20341 ctacaccaaa caagtgtttg tttgtatctt cgtatttgtt cttgatgaag ccgtactcag
    20401 catttgagaa gacaaggttg ataactggaa ggtcgtattg aacgtttgtg ataacgtctg
    20461 ggtagcacat gttgaatgct ccgtcaccca tgatgttcca tacttggcga tctggattgt
    20521 ctttcttagc agcgatacca ccaggaaggg caatacccat tgtcgcaaag agtggagatg
    20581 tacgccacat gttcttaggt gtcatgtgaa ggtgacgagt agatgtttga gtagtgttac
    20641 ctacgtcgat tgagtagata gcgtcttgat cagcatgttt gttgattgca ttgtaaactt
    20701 gatacaattg caattcaccc tcagttttac cttcgagttt gttcatgtaa tcacgccagt
    20761 tttggttgtt cttaacgttt gcacgccacc atggagttga ttcaactggg tttactttgt
    20821 caaggatagc tttagctgct tgaccagcat caccaaggat tgaagcgtca agggcatgac
    20881 gtttaccaag tttgtaaggg tcgatatcaa cttggatgaa tttttcagtg ttcttgaatg
    20941 cttcgtaaac ttcagcaaat gggaagtttg aaccaaggaa aagaactgtg tctgcttcaa
    21001 agaccacttc gttggctggt ttccaaccaa cacgataagc agaacctgtc aaaccttcat
    21061 agttccattc gaaagcttca aagtttttac cagttgtgat gattggtgct ttgattttac
    21121 gtgacaattc agtaatcact tcaccagctt taacaccacc aaatccagca tagataactg
    21181 ggcgttcagc attgttcaag atttcaacag ctttgtcgat ttcaacttcg ttcaaagcag
    21241 gagcgatgaa tgagcgttcg tatgaacctg aaccgtagta tgagttttcg tcgatttctt
    21301 ggaaaccgaa gtttactgga atttcaacaa cagctggacc ttttttagaa actgcagcac
    21361 ggcaggcttc gtcaattact tttggcaatt gctcagcgta agctacacgt ttgttgtaaa
    21421 cagcgatacc gttgtacatt gggttttggt taagctcttg gaaagcatcc atgttcaatt
    21481 cgttaactgg acgtgatcca aggattgcta ggaatggagt gttatccata gctgcatcgt
    21541 aaacaccgtt aatcaagtga gtcgcacctg gaccacctga accaactgca accccgattg
    21601 agccgccgaa tttagcttgc ataaccgctg caagagcacc tgtctcttcg tggcgaactt
    21661 gtaagaagcg gatatctttg tcttcagcca aagcgtccat caatgagctg agtgttcctg
    21721 atgggatacc gtagattgta tctacgcccc atgttttcaa tacgttaagc attgctgcag
    21781 atgcagtaat tttcccttga gtcataatga taactctcct tcaatttttt tagacttgga
    21841 gaatacgatt acatagaatt ggaaacgttc tccaaatttt tactattcca ctgtatcata
    21901 tttatgctga cttttctaaa aatctgctca aaactctcta ttctctattc taatacagtt
    21961 ttgaaagtgt cgtcatttct gttttataac aaaaaaatct agtcattact tttagtctat
    22021 tttactaaaa tttaacagaa gggaactggt cagaacagat acagaactaa aggccatggc
    22081 tagacctgcc aattctgggt tgagagccag tccaacacct gaaaagactc ctgctgcaat
    22141 cggaattccg acaacattgt agataaaagc ccagaaaaga ttgagcagaa tacgatgaaa
    22201 ggttttctta ctcatgtcga aggcacgcac cactcctaaa agattattgg ttgtcaacac
    22261 caaatctgct gactcgatgg cgatatctgt tccagctccc atagcaatcc ccacatctgc
    22321 tacactaagg gcaggagcgt cattgatccc atcaccaaca aaggctactt tacctgactg
    22381 ttgcagttta tggatttcat gggctttttc ttctggcaag acgcctgcaa tgacctcttc
    22441 aattccgatt tgatctgcaa tagcacgcgc cacaccagca ttgtctcctg tcagcatgac
    22501 tgtcccgaga ccacgttttt ttagctgact gatggctagc ttagcatttt tcttaggaat
    22561 atcttgcaaa gcaagcaagc ctttgatttc attgtcaaca gctaagaaca caactgtctt
    22621 agcttctttt tctagttctt ctagtttatc ttgataagta ttagaaatat ccatgccatc
    22681 cagcatttta gcatttccaa gtaaaacttg ttttccattg attcgccctg aaacaccttt
    22741 cccgtgcaag gcctgaaaat tttcaacagt ttgaaactca agtccagctt cactcgctcg
    22801 cttaacgata gcctcagcca gtgggtgttg agaaacatct tccaaggagg ctgccaatcc
    22861 aaacacttct acttcgtcgc cgatgacatc tgttaccaca ggtttccctt ccgtcaaagt
    22921 cccggtctta tcaaagacaa gggtttgaac tttctggatt tcctgtaaga cagttccatt
    22981 tttgaggaga acccccatct tggcactacg tcctgtcccc accataaggg ctgtcggtgt
    23041 tgcaagtccc aaggcacaag gacaggcgat aatcaaaacc gccactccgt agagaagaga
    23101 ggacacaaag ctagctccaa gcacaaccac actatccctg agcaagacga accaaaccca
    23161 aaaggtcatg attcctaaaa tgacaactac tgggacaaaa atccctgaaa tcttatccgt
    23221 caagtcctga atcggcgcac gacttgtctg agctttcttc acaaaatcca caatctgagc
    23281 caaaacagtc tctgagccaa ctttttctgc tctaaagaca agcgttccac tatgattgat
    23341 ggttgagcca atgacagtat ctccaactgt cttgtccaca ggcagactct cacctgtcac
    23401 catggattcg tcaatactag agacaccttc tactacgaca ccatcaacag caatcttttc
    23461 accgggacgc actcgaatca ggtcgcctac cttgacttgt tccaaaggaa cttggacata
    23521 actatcatca ctcaagactt ctgcggtttt agcttgcaag tccagtaatt tctccacagc
    23581 ttgggacgta ttttttctca ttttttcctc aaaaactgct cccaaaagaa cgaaaaagag
    23641 gataaatcca gcactttcga agtaaacagg gagaccagca aagagagcaa ctaggctata
    23701 gaaataagcc actagagttc ccagcgcaac caaggtatcc atgttggcat tgtgcttttt
    23761 aaaactggcc caagcactct ggatatatgg cttgcctgca actaacataa taggcgttgt
    23821 tgctagaaag gttccccaat gcatgacttg atgactaatg ctacctgcca acatcccaat
    23881 catgagaatc acaagaggca cagtacagat actagtaatc caaaaacgtt gcaggagaga
    23941 tagagatttt cgagtcttct caacgactgt atagcttccc ttttgcatct tcatgccaca
    24001 agaaaattca tgtcgcccta attcttgagg tgtaaaacga atgactttct cctcatctac
    24061 gccgattggt tccaagatac cttcttcttc aaacagaatt tccttataac agtttgaagg
    24121 agtagcacga tgaaaggtaa tctcagctgg aattcccttt tgaagctgga tatgggctgg
    24181 atgatagcct ttttcagctt ggatacggat tttttgaatg ccattttcta agcttgcttt
    24241 cacaatttct gtcatagtct ccacctactc tacaatcatc ttgccgtgca tcatgttcat
    24301 accacaagca aagctaaact ctccagcctg ttcaggcgtg atttccacta catactcttc
    24361 ccccattggc aggttcgcat gtacaccaaa atctggaaaa acaatttgat ccagacatgg
    24421 tgaaggatcc ttgcggtcaa agacaatgcg ggctggcact gatttcttga ggacaatcaa
    24481 ctcaggagta tagcctccca tgacttccac tcgaatctct tggtatccgt ttttttgctg
    24541 ggctttttgt ccagattttt caggcttttt gaaaaaccaa aacaagataa acgcgataag
    24601 ggcaatacaa ataatggtta caatactatt taacatgacg tctcctttac atacaattac
    24661 atcttacttc tgttacagca cttgatttct tctctgaaat cacagcttcc aagtcttcca
    24721 agtcagtctg agtaaattca cattctacaa tcaagtcagc caacaaattc ctaatcctac
    24781 gggaacaaac cttgtctttg atatcttgga caagtaaatc ccgactttgg tctagagtta
    24841 aaagcgctga ataaacaaag gacttgcctt cttttttccg agtcaaacac tctttctcaa
    24901 ctagacgagc caaaagtgtc tgaaccgtgg acttggacca gtcaaaccgc tctgccaaaa
    24961 ccctaatcaa atctgtactg gtctgctccc cctgcatcca aataatcttc atgacctgcc
    25021 attctgcatc tgaaatctgc attaccatac ctccaaaatc tacatttgtc aattacactc
    25081 aacagtatac tcccaaaatc tacatttgtc aattatagaa ataatatttt cttcgaaaaa
    25141 tagaatttta atcatttgaa aaacgatttg cagtcaaata ttactatata aacaataaaa
    25201 atatgctata ctaaagaaaa aagaaaacaa ccactagggg tgcgtaaagc tgagattaac
    25261 gactgttaga tccctctgac tcaatctagg taatgctagc tgatggaagt ggaaatgata
    25321 atggggacta gcagtcttct attgcctttc taaaacagac tagcttgttc ttaagaatac
    25381 aaacttcagt tggttgggag gttttagatg acttatttac ccgttgcttt gaccattgca
    25441 gggactgacc ctagtggtgg tgctggcatt atggcagatt taaagtcatt ccaagcgaga
    25501 gatgtctatg gaatggctgt tgtaaccagt cttgtcgctc aaaataccag aggtgttcag
    25561 ctaatcgagc acgtttctcc tcaaatgttg aaagcccaat tggagagtgt cttttctgat
    25621 attccacctc aggctgtaaa aactggaatg ttggctacta ctgaaatcat ggaaatcatc
    25681 caaccctatc ttaaaaaact ggattgtccc tatgtccttg atcctgttat ggttgctaca
    25741 agtggagatg ccttgattga ctcaagtgct agagactatc tcaaaacaaa cttactacct
    25801 ctagcaacta ttattacgcc aaatcttcct gaagcagaag agattgttgg tttttcaatc
    25861 catgaccccg aagacatgca gcgtgctggt cgcctgattt taaaagaatt tggtcctcag
    25921 tctgtggtta tcaaaggcgg acatctcaaa ggtggtgcta aagatttcct ctttaccaag
    25981 aatgaacaat ttgtctggga aagcccacga attcaaacct gtcacaccca tggtactgga
    26041 tgtacctttg ctgcagtgat tactgctgaa ctagccaagg gcaagagtct ttaccaggca
    26101 gttgataagg ccaaggtctt tatcacaaaa gctattcaag atgcccctca actcggtcat
    26161 ggttctggtc cagtcaacca tacaactttt aaagattaag aaaaaaaact ctctagttcc
    26221 cactttaagg gaattagaga gtttttatac tcttcgaaaa tctcttcaaa ctacgtcagc
    26281 ttccatctgc aacttcaaaa cactgttttg agctgacttc gtcagtctta tctaaaacct
    26341 caaggcagta ctttgagcaa cctgcgacta gctttctagt ttactctttg attttcattg
    26401 agtattaatt aggaaagaat gtcatgcaac tttgttaaaa aggcttgcgt ttttgcctca
    26461 atatcttctg cttgcatcaa atcacgtaca acagctacac cagctatgcc agtgcccata
    26521 agctgatcaa tattctccga agtcaagcca ccaatagcaa ctattggaat ggcaaccgtt
    26581 tggcaaattg ttttcaaggt tgaaatcagg gtgatgggtg cattttcctt ggtggttgtc
    26641 ggaaaaatgg ctcctgtccc caagtaatct gcacctgatt tctccgcttc cagagctctt
    26701 ttaaccgttt tagcggtgac accgaggatt ttttcaggac ccaagacttg tcgggcaacc
    26761 gaaactggga gttcgtcatc tccaatatgc agaccagcag catcaaccgc aagacaaaca
    26821 tccaaccgat catcgattat caagggtacc tgataagcat ctgttatttc cttgacttgt
    26881 tttgccagtt gataatattg attggttgtg agattttttt ctcgcaattg gactatggta
    26941 acccctgaac ggcaggccgt ctcaactttt gcaagaaagc tttccacgga atcttgatag
    27001 cgattggtta ccagatatag tctaagtgct tctctattca taaacctctc ctttgatggt
    27061 atctagccaa ttttcatctc ttcttaggag cgaaagctga ttgagtactt ggtaacgaaa
    27121 ttcttccaat cccattcctt gaacaactat tttctcagca gcgatattga gataagagac
    27181 tgctaagcaa gaagcttcaa aaccagtctt tccttggctg agaaaaacgg ctgttaaggc
    27241 tccaaccaaa tctcctgtcc ctgttatcca gtctaattct gcacagccat ttcccagtac
    27301 agcgacctga tttttcgaaa cgacgaggtc cttgggacct gtgactaaga aagacatacc
    27361 atgataggtc tgacaccagt ctttcaagac ttgaagcaaa tcctccgttt cttgatcttt
    27421 agcactcgca tcgaccccaa cgccgtggtg ctttaatcca acaagacttc gaatttctga
    27481 catgtttcct ttaaggaccg taggtctata gtctaaaagg tctctgacta agctcttacg
    27541 aatggatgaa gctgttacgc caaccgcatc tactaccatt gggagacaaa cttgagctgc
    27601 ataagaagct gctatacgga ttgctttctc cttctcagct gacaaatgcc ccaaattgat
    27661 gaagagagcc tgactttgct tagtaaaatc aagaacctca cggggatcat ctgccatgac
    27721 aggtttgcat cccagagcca aaatcccatt tgccagcatc tcacaagaaa tctcattggt
    27781 catacagtga atgagggaac tagagcctat aggaaaggga tttgtaaatt cctgcatcag
    27841 tctatccttt cactaaagaa atatccctgc acttttttaa agaattcctg cttgattaaa
    27901 aatcgaaagg caataaagga aatcgctgta ccaatcaagg ttgctccgaa aaatcgaggc
    27961 gtgtagataa accagctaag cttagcagct gatcctgtaa agagtaccat aacaggatag
    28021 gaaacaatag aaccaataat acctgttccc acaatttctc ccaaggcaga aaagtaaaat
    28081 tttcgaccgt acttataaaa gagacctgct agaagggctc caaaagtcgc tcctgtgaga
    28141 gctaaaggcg gaatcccttg agtcgtcata cggataaagg ctgtcactgt agccatagcc
    28201 aaggcataaa caggtcccat catgattccc gctagaatat tgactacact ggacatcggt
    28261 gccattccct caatccgaaa gataggtgta aggactacat caagggcaat catcatagat
    28321 aaaatggtca atttgtgaac ttgtagttgg tgctttctca tgtttctatt cttctccttt
    28381 ttctaaagac tgtaaatcgc tcttccatgt ctggtgttgg taagccatct cccaaaactt
    28441 ggcttccata tgaacactga tgtggaaggc atctagcatt ttttgcttat ctgtctcatc
    28501 actttctcga tagagctgat tgaccagtgc tccctcctct ctgatctgtt gctctaactc
    28561 atccgtaata taagtttcaa tccattgttg atagagagga tttggtgatg gtttaagatt
    28621 aagtgatttg cctatatcat ggtataacca aggacaagga agcaagcttg caaaagcgat
    28681 ggctaagttc ggttctgcaa attgcctata aatatgagaa atgtaatgat aacaggttgg
    28741 agcgattgga tgttgctcca tttcctggtc gctgatttcc aattccttga aaaattgttg
    28801 gcgaataaat aactcaccct ccactaaacc ctgagcattt tgtttcaaga gtcttttcat
    28861 ctcttggttt gaagtcttat cagccaaaag atgatagatt tctgagaaag ccttcagata
    28921 gtaggcatcc tgaatcaggt aatagcggaa aatggcaggt tctaaattcc cctcttgtaa
    28981 ttgtaaaata aagggatgat gaaaggaagc ctgccaagct ttcttggata attccatcgc
    29041 aatatctgta aattccataa taactccttt ataaaaatag actggtttga agcaataaaa
    29101 agaaaagcag gtagattaat tttgtttttt taggaatata aaaagtccga tagctattct
    29161 tcaactgtgc atgttcgtca tatccgtgag cagatagagc tctcaggtaa agatggcgcc
    29221 acctaaagac tgtcatcaga accttactgt aaatcaaggg cgaccaaaaa tgtagttctt
    29281 gaccacgtaa taggcaagct tctttgaggg acttgatttc ttgctgaatg agaggaaaag
    29341 aattgaatac cacaatcaag gcataggacc aagagcgtga tagccccttt tgagccaagt
    29401 acaagagaag ctcttttagt gaaatagagg aaacaaagac aaggccgata caaactgtca
    29461 caaaggccct cgttccaagc atgactgcct gtgaagcatc tccgtgtaac tgaactgccc
    29521 agtagttggc aaaagatggt aaaatggcaa gtatgatcat ccaagctaac attttaaatc
    29581 gacggtaata gagcataaag agaatacaaa atgcgactac cgaaagattc agagcaatcg
    29641 aaggaatgaa agatgtttcc aaggataaaa tcagcaagaa gagactgata atcggtgtct
    29701 gggttgctac tttgaccata ctatctcacc tccccttggg tattgctact ctgagatgta
    29761 agtggtttgg taatggtcac ttctttcaca tgccgaagac cctgactagt catctcaatc
    29821 caataatcaa ccacagaaat caaagggtct aaacgatgac taatgagcag aaaacttctt
    29881 ccttgattcc tctcctccac aatccacttg caaaaataat ggcaggctct atcatccaaa
    29941 cctgcaaaag gttcatctag caagatcacg gaagccttac tggtcaagat ggtcaggagc
    30001 tgaagaattt tttgctgacc accatttaat tgatagggac tcttatcgac tgcctgctcc
    30061 aaatcaaaat atcgtaaagc ttgaaaaatc cgctgatttc tttcagaatc aggtccatct
    30121 aattgaagct cctctcgcag actgactcgg ataaactgct tctcagcttc ctgaacaaca
    30181 ccagtcagat cacgatacaa actctttttc tttttcagga ccgaaccctt ccatgcaatg
    30241 cgccccttat acttttgaaa ttgaagaata gaccgaaaga gggttgattt cccgacacca
    30301 ttgtcaccca ggatacagga aatcccttga tagaatgtga aatcagcaat tgaaaagagg
    30361 gggcgatttc caaactcaca agtcgttcta tccatatgga atagttccgg gctagaagca
    30421 acttcctttg aagcaacctg tgtcatctca taggaaggga tttgaaacac ttcccttagt
    30481 tttccgtctc ttagctcaac catatggtcg atataggctt tatagtcaga taaatcatgg
    30541 tcgcacaaaa taactgtctt tccatcaaga gccaactctt ttagaatctc caatatctcg
    30601 attctgctct tgcggtcaat ggaagcaaaa ggttcatcca agagatagac cctaggattc
    30661 atggcaaaga ggacagccag cgctgctttt tgcttttccc cacctgatag gtgatgaatg
    30721 ggacggtgta agattgcctc gcaacgacat tgctggacaa cctctgctat tttagaatca
    30781 atttcctgaa ggtgatagcc gatattctcc aaggtgaaaa tcagctcctc aaacaagctc
    30841 tccatggtaa attgatgatt gggattttga aagagaatgc caaccttctg gacacgtgcg
    30901 atgatagaaa gttgactgac ctcgctccca tctatcagga cttgaccact atagggaaga
    30961 gaactgactt gggcaatcat ttgaaagagg ctggattttc cagacccact actcccaact
    31021 aacaaggtaa aggcttgcgc atgaaaagta aaatcaaacg gctcagagaa gattggggac
    31081 tgaatcgctc gtagttccag acccatctat gcttttcctc cagttgcaaa ctgatgatag
    31141 agtttgacaa tggcacgaac caagatggta cagaagaaat aaacagaaat aaaacgtacc
    31201 acaagtaagg aaaggacaaa cggaagggaa aaggcgtagt aacctaactt aatgtattca
    31261 tagacaaagc taacaagcgt aatcccaata ctattagcag ttagagagag ccaactttca
    31321 tagcgattct tagttacgat aaaaccaaat tcacttccca aaccttgaac caagccagac
    31381 aaaagagctc ctagaccaaa ttggctacca taaaggactt cagcaagcgc agctagcact
    31441 tctccaatcg ttgcacttcc gactctcgga acaaagatgg cagcaatggg cgcagccata
    31501 caccagagac cgaagaggat ttcattggca aaggcctgca aaccaagagg tgttaagagt
    31561 agactgagaa tattatacac atatcctgaa ccaacgaaaa ccccaccaaa aaagatagac
    31621 aagaaagcaa gcaagataac atcttttaac tgccattttt tcaacataaa aaactccttt
    31681 ttttaaagaa aagtggggca ctcaagaaga ccgacctaaa tactttgtat agcagactga
    31741 atttagaaca gtacacaaga atgctaaaat atttctagaa attaatttga attttctaat
    31801 tgatttgttc gcatcttatt tcaatctact atatcatctt catccagttt cgtaaaagaa
    31861 aaaactctaa ttacagatac gaattagagt tcagcttaca agattagaca gttcttttcg
    31921 acatacgaaa aaaacatttc acatttccct tcgccagtct taactgtatc aggttcaatg
    31981 ggtatcatct cagcctaaag caccccaaat gtctttatta tttaattatg tgattattat
    32041 aacacacatt ttatactagt tcaagaaatt gaactggaaa tacagccttg cactcacaaa
    32101 gacagcagat ctttcttttg caaaaaacaa atgacctgtt tgatgaatta gccattcaag
    32161 ctgaatctag acatagcttt ttaaaaaagg aaaatcctac ttacttagaa tccaaggata
    32221 gatatctatt gttcactcat ttcccgaaca gttttttcta tattttttgc atacgatatt
    32281 gccgaaatga ttgaaacgcc atccatattg gtctttataa tgtctttaat atgtttcgtc
    32341 tgtatcccac caattgcaac taagggcatt tgtggcaaca gttttctcat caatttaaca
    32401 ccttcataac ctatagcacc accagcatca tcctttgact gggtatcaaa tacaggccca
    32461 acaccaacat aatctacata ttcaactttt gattgttgaa attcttcctc gttttttata
    32521 gaaagaccaa ttattttatc tggcatcaat tttctaattt catcaacacc aatatcatct
    32581 tgacctacat gtacgccatc agcgtcaatt tccattgcta aatctatatc gtcattaacg
    32641 ataaatggaa cattgtattt tttacaaagt tctttaattt ggatagctag ctcaagtttt
    32701 tctaagcctt ctaaagcacc ctcacctttt tctcgaaatt gaaataaggt tataccacct
    32761 tttaaggctt cctcaacgac tgtatataga ttttttcctt ggcaagtagt cgttccacaa
    32821 ataaaatata gttttagtaa ttctttatga aacatcttac ttcactcttt tgaattcctt
    32881 tacatcttca tctgtaatct cgtataaggc atttataaat tcaactttaa atgtcccagg
    32941 aagatgtcca tttggacgtt tttctgccat ttctccagcg atattgtaaa ccaacattgc
    33001 tgtttctaat gatttcaatt cttgaccttt ttctagtccg ataaagcttg ctactacagc
    33061 tcctaataag catcctgtcc caatgacttt cggcatcata gcactaccat tatgaatcgt
    33121 taccacttct ccattaacag caatggcatc cacttcacct gttactacta ttggaatatt
    33181 gaacttctca tttgctgcta gagcaatttc gtcaatatta tctacgcccg cactatctac
    33241 tcctttagat gccacatcta ttcctactaa agaggcaatc tcgccagcat ttcctctaat
    33301 cgctgctagt ttataattgt tgattagatc atctgctact ttttttctat attctcctgc
    33361 tccacaggct acaggatcta aaactgctgg gacattatat ttctccgcaa ttttcagagc
    33421 agcttggtat aatttccaat tttcatctgt caatgttcct atgtttatta ataaaccacc
    33481 agcatacttt aacaaatcct ctaaatctgc tggaaactca ctcatggctg gtgagacgct
    33541 cagtgctact aatccatttg ctgtgaaatt ttttactaca tcattggtga tacaaatgac
    33601 caatggtgct ttttctttta ataattttaa acttgtcata ttgaaatcct tccttttcac
    33661 tttatacgat ctactgattt cgatttatct ttagttgaga atttttttca tttacattga
    33721 atgatttata ctcaatgaaa atcaaagagc aaactaggag gctaaccgca ggttgctcaa
    33781 aacactgctt tgagcctgta gataagactg acgaagtcag ctcaaaacac tgttttgagg
    33841 ttgtggatag aactgatgtg gttcgaagag attttcgaag agtcttacct catcaaattt
    33901 gtaaatatca tgagccttct ctagacatcg taaccaatat caaaaaaagc taattctaaa
    33961 gcgactgctt gattccagcg ttgctgaagt tctgtcaaat cttctcgatt tttaccgaca
    34021 cgattgagtt cgtcaaccag aaattgaacc cactcttcaa agaaaggacc tctgtggaga
    34081 ttgatccatt ccgaatgaat atagacttca ggtaaagcca aatctttaga accccagtct
    34141 aaatagagac cttctgcaat gaccagcatg accaaaagat gggcatagtc tgatgaagcc
    34201 accgccgaat acattagatc ctgaaaggct tttgttacag ggtgcaaagt cacttctaga
    34261 tagtcattct ctgctacttt taactcttta aaagcctttt ggaaataacc atcttcatct
    34321 gcttcaagaa agcctagttg cttggcaaaa cgaagcttgg attcaagttt atctgcgtga
    34381 gctacgcagg cacccagcat ggataagaag gcatcaaaga agtgataatc ttgaatcaga
    34441 tagtccttta agaccttatt ctcaattgtc cccgcaaaaa gttccttaac aaaacgatga
    34501 ttgattgcag cctgccaatc cttctgactg ctttttaata attctccaac agtcaaacct
    34561 ggctgaaatg catagtcttg tgtttccata tttacttctc ctctctttac ttgttagtaa
    34621 ttaataaaac accaagaaat atcaagcaaa atcgtaattc cacttgatcc ttttaaagca
    34681 catcgagagc atttgcagag aagctaacta aacaagccta tccagtttat ataaacaaaa
    34741 aactccaatt acaatcaaga attagagttg acttacaaga ttagatcgtt catttcgcca
    34801 tacgaaaaaa cgtttcacat ttcccttcgc cagtcttaac tgtatcaggt tcaatgggta
    34861 ttatctcagc ctaaagcacc ccaaatgtct ctattattta attactgaac cagtatagca
    34921 aaaaatgaaa gccttagcaa gatatttaac cgaaaaatat ctttatatat agtagattga
    34981 aactagaata gtacccctct acttctaaaa cattgttaga aatcgattta actgtcctga
    35041 ttgatttgtc ctattcttat ttcattttac tatagttttc gatagcgatt tattcttcca
    35101 atacacgaag aaaaacctcc acattcagtg gaggcaatct gttttatcaa tacaatttta
    35161 agtcacgagg gtcaactggg aaggttgggt tgtatggatt gtgacggagc ttgaagtgtt
    35221 tgacatcttc aatggtctga gctccagaca attgcataac tgtcttcaat tccgcattca
    35281 agtgttcaaa gacttgacgc acaccgacac taccaccgag agccaagcca tagatgacag
    35341 ggcgtccaat agcaaccaag tctgctcctg atgccaaggc tttaaagacg tgttgaccac
    35401 gacgaacacc agagtcaaag acaatcggca cacgtctatc aactgcttct gccacttctt
    35461 gaagcgagtc aaaggcagct ggtccaccgt cgatttgacg accaccgtgg ttggttaccc
    35521 agataccaga agctcctgca gcaagcgaac gttcaacgtc ctcacggcat tgtggtccct
    35581 tgacatacac aggaagacca gagtattcag cgataaattc tacatcgcgt ggagacaagc
    35641 gttgtttagc tgatttgtaa acaaagtcca ttgatttacc agcaccttct ggcaggtatt
    35701 cttcaacaat cggcatgcca actgggaaga caaaaccatt acgcttatcc acttcacgat
    35761 tcccccctac agtagcatct gccgtcaaga caatcgcttt ataaccttca gccttcacac
    35821 ggtccatgat gtggcggttg ataccgtcat ccttactaaa gtaaaattga aaccaatgag
    35881 gtgtcccttg aagggcttca gaaatctctg gaaggtcaac agtagagtaa gaactggttg
    35941 tataaagaga accaaactca tgcacaccac gcgcagtcgc cacttccccc tgttcatttg
    36001 ccaatttatg ggccgcaaca ggtgccataa tgattggcga agatagtttt tcacctgcaa
    36061 attcaatctc tgtacttgga ttttcaacat cgcaaagtgt atgaggaacg atgagtttgt
    36121 ggttaaaggc gcggatattc tctcttaaag tgaaagtatc ttccgcccca ctagcgatat
    36181 agccaaatgc tgctttagga ataacttgtt gcgccattgg ctccaaatca taggtattga
    36241 taaagtctac atgaccttct gcattgcttg ttttgtatga cataaactgt cctcctcgat
    36301 taagtaagcg tttgcttttt actatacaac tataataact cttttttcaa tcattttcaa
    36361 gagttttgct taaaaaccat cttatttttt catacaatat actagcccta cttcccttaa
    36421 actctaaacc ttagtctata ttaagtgaat cgttgagatt ttttgctgcc aggcatttga
    36481 actacttttt tatttgctga ttctatctac taatactata aaaaacaagt gaataagaca
    36541 ccagaacatc ctctaatagg acctatggac ttatatcagt cccatatata ctgtttaagc
    36601 aagatactat cctagttgac gctaacttcc tatcccactt attaattttt tatttatagt
    36661 gaatctgaac aaatcaattg gggaatccaa gtcaatttct agtacttttt gaaaagtttc
    36721 agcgtactat cgtaaaatga aataaaacat gcacaaattg cttagggaat ttaaaccaat
    36781 ttctaacaat gtcttagaaa tcaaagtgta ctatttcaac ttcaatatac tacacttcat
    36841 tttctcctta aattcagtct ctttttgaat caaaaaatcc tctggtaaga gccagaggat
    36901 aagaattt
//
LOCUS       DAVMJI010000022        35851 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.022, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000022 DAVMJI010000000
VERSION     DAVMJI010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35851
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.022"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..184
                     /locus_tag="VYR58_001282"
     CDS             <1..184
                     /locus_tag="VYR58_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEV3622435.1"
                     /translation="VESFFGILKSEMFYGYEKTFKSLNQLEQAIIDYIDYYNNKRIKV
                     KLKGLSPVQYRTKSFG"
     gene            complement(312..1334)
                     /gene="cbpF"
                     /locus_tag="VYR58_001283"
                     /pseudo
     CDS             complement(312..1334)
                     /gene="cbpF"
                     /locus_tag="VYR58_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(1353..2174)
                     /gene="cbpG"
                     /locus_tag="VYR58_001284"
     CDS             complement(1353..2174)
                     /gene="cbpG"
                     /locus_tag="VYR58_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV3622436.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVNTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGNWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(2255..2494)
                     /locus_tag="VYR58_001285"
     CDS             complement(2255..2494)
                     /locus_tag="VYR58_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622437.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(2644..2910)
                     /locus_tag="VYR58_001286"
                     /pseudo
     CDS             complement(2644..2910)
                     /locus_tag="VYR58_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(2935..3246)
                     /locus_tag="VYR58_001287"
     CDS             complement(2935..3246)
                     /locus_tag="VYR58_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV3622438.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(3171..3412)
                     /locus_tag="VYR58_001288"
                     /pseudo
     CDS             complement(3171..3412)
                     /locus_tag="VYR58_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3413..4045)
                     /locus_tag="VYR58_001289"
     CDS             complement(3413..4045)
                     /locus_tag="VYR58_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3622439.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            complement(4059..5054)
                     /locus_tag="VYR58_001290"
     CDS             complement(4059..5054)
                     /locus_tag="VYR58_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV3622440.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FFFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5051..5749)
                     /locus_tag="VYR58_001291"
     CDS             complement(5051..5749)
                     /locus_tag="VYR58_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV3622441.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(5826..6836)
                     /locus_tag="VYR58_001292"
     CDS             complement(5826..6836)
                     /locus_tag="VYR58_001292"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV3622442.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(6820..7827)
                     /locus_tag="VYR58_001293"
     CDS             complement(6820..7827)
                     /locus_tag="VYR58_001293"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV3622443.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRADIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFFAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(7814..8767)
                     /gene="mvaD"
                     /locus_tag="VYR58_001294"
     CDS             complement(7814..8767)
                     /gene="mvaD"
                     /locus_tag="VYR58_001294"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV3622444.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(8749..9627)
                     /gene="mvk"
                     /locus_tag="VYR58_001295"
     CDS             complement(8749..9627)
                     /gene="mvk"
                     /locus_tag="VYR58_001295"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV3622445.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQAVLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(9749..10078)
                     /locus_tag="VYR58_001296"
     CDS             complement(9749..10078)
                     /locus_tag="VYR58_001296"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV3622446.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNDTLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            10741..11079
                     /locus_tag="VYR58_001297"
     CDS             10741..11079
                     /locus_tag="VYR58_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
                     /protein_id="HEV3622447.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLPLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
     gene            10979..11566
                     /locus_tag="VYR58_001298"
     CDS             10979..11566
                     /locus_tag="VYR58_001298"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622448.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHIFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
     gene            11609..12841
                     /locus_tag="VYR58_001299"
     CDS             11609..12841
                     /locus_tag="VYR58_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV3622449.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILYQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(12960..13976)
                     /gene="cbpC"
                     /locus_tag="VYR58_001300"
     CDS             complement(12960..13976)
                     /gene="cbpC"
                     /locus_tag="VYR58_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV3622450.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATDWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMATGWYQDGSTWYYLNASNGGMKTGWFQVNGKWYYAYGSGALAVNTTVDGYSVNYNG
                     DWVR"
     gene            complement(14074..14763)
                     /locus_tag="VYR58_001301"
     CDS             complement(14074..14763)
                     /locus_tag="VYR58_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3622451.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(14775..16199)
                     /gene="gndA"
                     /locus_tag="VYR58_001302"
     CDS             complement(14775..16199)
                     /gene="gndA"
                     /locus_tag="VYR58_001302"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV3622452.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(16275..17669)
                     /gene="mapZ"
                     /locus_tag="VYR58_001303"
     CDS             complement(16275..17669)
                     /gene="mapZ"
                     /locus_tag="VYR58_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV3622453.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(17682..18839)
                     /locus_tag="VYR58_001304"
     CDS             complement(17682..18839)
                     /locus_tag="VYR58_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV3622454.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREMRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(18924..19304)
                     /gene="rnpB"
                     /locus_tag="VYR58_001305"
     ncRNA           complement(18924..19304)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VYR58_001305"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(19325..19654)
                     /gene="gpsB"
                     /locus_tag="VYR58_001306"
     CDS             complement(19325..19654)
                     /gene="gpsB"
                     /locus_tag="VYR58_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV3622455.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(19724..20251)
                     /locus_tag="VYR58_001307"
     CDS             complement(19724..20251)
                     /locus_tag="VYR58_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV3622456.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            20317..20913
                     /gene="recU"
                     /locus_tag="VYR58_001308"
     CDS             20317..20913
                     /gene="recU"
                     /locus_tag="VYR58_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV3622457.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            20910..23075
                     /locus_tag="VYR58_001309"
     CDS             20910..23075
                     /locus_tag="VYR58_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV3622458.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGSRHQSSNVSFGINQAVETNRDWGSAMKPITDYAPALEYDIYDSTAS
                     IVHDVPYNYPGTDTPLYNWDKVYFGNITIQYALQQSRNVTAVETLNKVGLDRAKTFLN
                     GLGIDYPSMHYANAISSNTTESNKKYGASSEKMAAAYAAFANGGIYHKPMYINKIVFS
                     DGSSKEYADPGTRAMKETTAYMMTEMMKTVLAYGTGRGAYLPWLPQAGKTGTSNYTDD
                     EIENYIKNTGYVAPDEMFVGYTRKYSMAVWTGYSNRLTPIVGDGFYVAAKVYRSMMTY
                     LSEDNNPGDWTMPEGLYRSGEFVFKKGARSAWTAPAPQQAPTPESSSSTSESSTSQSS
                     STTPSTNNSANNNTNNQQPNTTPGQQNQNQNQNPQPAQP"
     gene            complement(23243..28546)
                     /locus_tag="VYR58_001310"
     CDS             complement(23243..28546)
                     /locus_tag="VYR58_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV3622459.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDTDNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIESLKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVAKTKKD"
     gene            complement(28847..30829)
                     /locus_tag="VYR58_001311"
     CDS             complement(28847..30829)
                     /locus_tag="VYR58_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV3622460.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(31150..32233)
                     /gene="glf"
                     /locus_tag="VYR58_001312"
                     /pseudo
     CDS             complement(31150..32233)
                     /gene="glf"
                     /locus_tag="VYR58_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476416.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(32296..33147)
                     /gene="rfbD"
                     /locus_tag="VYR58_001313"
     CDS             complement(32296..33147)
                     /gene="rfbD"
                     /locus_tag="VYR58_001313"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV3622461.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAKMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNIAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            complement(33213..34262)
                     /gene="rfbB"
                     /locus_tag="VYR58_001314"
     CDS             complement(33213..34262)
                     /gene="rfbB"
                     /locus_tag="VYR58_001314"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV3622462.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKTEKE
                     AVEANYAKTQEIITV"
     gene            complement(34272..34868)
                     /locus_tag="VYR58_001315"
     CDS             complement(34272..34868)
                     /locus_tag="VYR58_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV3622463.1"
                     /translation="MTDNFFGKMLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPASFFAAGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(34869..35738)
                     /gene="rfbA"
                     /locus_tag="VYR58_001316"
     CDS             complement(34869..35738)
                     /gene="rfbA"
                     /locus_tag="VYR58_001316"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV3622464.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSKMLQKAAKKEKGATVFGYHVKDPERFGVVEFDENMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
BASE COUNT        10265 a         8099 c         6365 g        11122 t
ORIGIN      
        1 ggtggagtcc ttctttggga ttctgaaatc ggaaatgttt tatggctatg agaaaacatt
       61 taaatcactt aatcaattgg aacaagccat tatagactat attgattatt acaacaacaa
      121 gagaattaag gtaaaactaa aaggacttag tcctgtgcag tacagaacta aatcctttgg
      181 ataaattatt tgtctaactt ttggggggca gtacagaaaa accttgatac tatgcgtttt
      241 ttgattgtga agacttttat ccacctatta tacaaagtta agtatccatc acagtttaca
      301 attagccttc attacttaac ccattcacca ttatagttta agtagtaacc acctactgtg
      361 gtattaacag ctaaagcacc tgaatcatag gcatagtacc agttaccatt gacttggaac
      421 cagcctgttt tcatatctcc attacttgca tttagatagt atcaagtcga accttcctga
      481 taccaaccag ttgccatagc tcctgatgaa cggagatagt accatttgtt cccaaggttt
      541 tgccagccag ttctcatatc accattttca gcatctagat agtaccaagt tgagccttcc
      601 ttataccagc cagttgccat agctcctgac gaatggaggt agtaccactt attacctaga
      661 tattgccaac ctgtttgcat aatgccagtt gctggatcta gatagtacca tggagctgct
      721 tttagcttct cttcatcata cgtaagaggg taatccttaa cccaaccacg tgctagctct
      781 ccaaccgtca atctgttgat gcgagaatca aagccaccat ccttctgtaa ataataccaa
      841 tgaccctctt cataaatcca accagttttt aaagtatgat aactacgctg atcttcaaaa
      901 taatagactc gtttctctgc ttggctatca tattcttccc catgatgttt gttggtattc
      961 gtagcagttt ttgcttctaa aacttgcttg ccaacaaatt cttgtaagac accatcttga
     1021 ccaaaataaa accaatctgg tctaagagca atctctattc ttggagaagg accaatcgta
     1081 acccccttgt gtggagcagg tatatattgc cagccgacaa ccatctctcc ggataaagga
     1141 tcaaaataat agtacttccc atctatcact ctccagtagg tttcttttag agcccccttt
     1201 ttgtagtagg ttctaccatt ttctttgaca aactgccatc cttcagaatc atctgcaaat
     1261 actgtactgg tccctagcaa accgaagaaa aatgtggcta gtgcgacttg catcattttt
     1321 ttcaaaagct tcattttata tatcctccaa catcaaatcc actcaccaga tgaagcgaag
     1381 ttataaactt taccatcgat agtttggcta cctgtaacca ttgctccatt tgaattgaga
     1441 taataccagt ttccatttac tttttgccaa tctgtaagca tcttaccgga actgtctaaa
     1501 taataccaag tatcatttat ctcctgccaa cccgtttgtt tatcatgttg tctataatag
     1561 taccaactac catttatttt cttccatcct tcaagagagt aacctttaag aaccgaataa
     1621 ataaatggca aatttcgttc atttaattta actgcactgt taatttgatt agctccatct
     1681 cctaaagtat gcactcctac tacacggtga ctagcatcat aaactgtaga tccactagac
     1741 ccctctaaag tattaacttg gtaatccaag aacatgccat catcacttaa aacttgtttt
     1801 ttatctgtat acatttgatg aattttaaaa ttatatgata gatagcctgt gatagtcaca
     1861 gttattcctg tcaaattttt ttgactagta ggaagaccca aagtccctaa ttttgcacca
     1921 atgggctctt ctagaattaa taaagccaag tcatattccc ttgcatcctt agaatttaaa
     1981 tttctaaatt ccttcaaata acgaacttcc tttactttga tctttccaaa tagttcttga
     2041 cttggactaa cagccggaag aacataaata tcatccgctt ctttcccata gtcatgtctg
     2101 tagtagttgt gagccgctgt aattaacaca ttatctttaa taaaattcgc acttcccctc
     2161 ccttctacat tcattccatc ggctactcca taatacttag ataaaaccat agctgaagtc
     2221 gaatacggat actgtaaagt attatcaatt ttaatcaaat catcattacc gataatactt
     2281 ctgattgctt ttggtagtat gaaccatacg ttggtgaaat ctcagataat gaagaatcat
     2341 tagactctgg acctttttct agtgtctcac ttacctcata ttcttcacct gtactagaaa
     2401 taacactcaa agcagatact gtcgataact ggctagccaa taaagtactc gcaataattg
     2461 aaatacccaa ttttttataa acagttttct tcattattgt atcctcctaa tgtaattata
     2521 gcgtactatt ctaaatttct taatctacta tagaatcaag aaatctacca ccttctttaa
     2581 ataccctcca ttatcacata aacaggtaaa cttttcaatt aatgactgcg cttttcaatc
     2641 acgctagagg tacttgcttg cttctttgat actaagttca gccattcttt ccttgttttt
     2701 ctcaataaag catgttaccc aagtgggatt cgttttggag tagtctcgca gagtccagcc
     2761 aatggcttta ttgataaaaa attctgtttg gttcaagtta tgaagtagaa tcttttccat
     2821 taattgagta ttggtcttct cttttcttaa caactggtgg tcaatagcga cacgtctcag
     2881 ccagatatta tctgataggc tccattttat actcaatgaa aatcaaagag caaactagga
     2941 agctagccgc agattgctca aaacactgtt ttgaggttgc agatagagct gacgtggttt
     3001 gaagagattt tcgaagagta ttaagattat ttcttctagt tcagagtgtt catacaccaa
     3061 actccctact actcgatcta ggatatctac cgtgtcccac caggattttg tcacgactaa
     3121 ctgctctagc ttaggcaaat cggtttcctt tagataagac tgcattgctt tcaaatagtt
     3181 agcagccaca tattggtatt ctctaggatc cttttcccag caagtgtctg caaaatccca
     3241 atcgataatc tttgtttttt tcgcttctgg aaaatatttt tatagagttt atttctttca
     3301 ggcaccgcaa tacctagaaa agaaaattga tggcgcatat aggcttccat gggccttgct
     3361 ttttagagtc ttttgctgct tctagctcct caagtaaatc tgctaaactc atctaaaact
     3421 cctcatgccc caccaaatgg tgctgaaagg catagacagc cgcctgggta cgatcgctga
     3481 cttcaagttt ggcaagaatg ttggacacgt gggtcttgac cgtcttgaga gagataaaga
     3541 ggtcatctgc gatgcgctga ttttcgtagc ccttggcgat gagttggaga acatctcgct
     3601 cacgcgcagt caattcttca tgaagttcca tatgattgcg gtggtattca accttcttgc
     3661 taacctcttg ctcaatggcc agctcgccag cagctacctt actgacggca tgaagcaatt
     3721 catctgcact agaagtcttg agcatatagc ctttggcacc agcatctaag actggcatga
     3781 ttttttcatt gtccaaataa gaggtcacaa tcaaaatctt ggcttcaggc cattctttaa
     3841 ggattgctaa ggtcgcgtca atcccattca tctcaggcat gacaatatcc atgacaatga
     3901 catctggacg cagttccaag gccaagtcaa tcccttgaga cccgttggac gcctcaccta
     3961 caacttctac atcgtcttgg aggtcaaagt agcttttcaa gcccaatcgg accatttcat
     4021 ggtcatctac tagtaaaatt ttcatcttta ctcctttatc attccttatc taacagggga
     4081 atacggatat caaccgccag cccttgcttg ggagctgtca agagttgaac tgttccagcc
     4141 atatcttcaa cccgctcctt gatatttcgc agtccataac tcaagtcgtc taagctccct
     4201 aactggaaac caatcccatt gtccaccacc ttcagttgca attcaacatc tgtctgatag
     4261 aggtagacat ctaggcaaga tgcctgggca tggcggagcg tattgctaat caactcttgc
     4321 aggatacgga agatatgctc ctcgattttc ttaggcaatt tcgtcatatt ctgcttgaga
     4381 ctaaccctaa gatcactctt gtcctcaagc tcttttaaaa gaatttgaat cccttctatc
     4441 aagctcttct gctccagttc aactggtcgc aaatgcaaga gcaaaacccg caaatccttc
     4501 tgggctgttt ctaaaatagc tgtgacactc tgcaactggg tctgcatctt ttctctatcc
     4561 aatttcaaag cctgctgact gatacccgat aaaatcatgt gggccgcaaa caactcctga
     4621 ctgactgtat cgtgcaaatc ccgagcaatt cgcttccgtt ccttctcgat gatttcctct
     4681 tcctgagcaa ggctatgatt ttcagctttt tgaagagcct ctgtcaaaag gttaagttta
     4741 cctgataagg acttgaaact ggcatccaaa tctggatcta caacctgaac cacttcttgc
     4801 cctgccaata aacgcttgag attagcctgc atttttctta gagaaagctc ttcgatccct
     4861 cgccaaaaca gggctaagag acaggtcatg gacatgctga aaaccaacaa taaaaagaaa
     4921 aatttttctg ttttttcgac atcgtgcaaa aagatagacc agtcaaaatc aagtatttcc
     4981 agcaagctat gggagaaaaa aaagacaaac aggaaggagg tgagagcgat aatgacatag
     5041 gcttgttttt tcatcctcta accacctcaa catcaccaat catagtggtc aagaaaatct
     5101 tgacactctt gttactcttg agatagtctt ttgtttcttg atgatagtgt tcattgcgga
     5161 gggctcgctt gggctggttg aaaaaagtca aatccccata gagacagtta acgctgagac
     5221 tgacttccac atctacaggt acgatgattt tggtcgttcc taccatcttt ctgaggataa
     5281 tgacattgtc atgattggtt aagatgaccc tctccagatg aatagtgtcc ttgcccatga
     5341 agcgaaagag attgatatca tcaaattggc aagtctggta gcttgaaaaa tgatgaagat
     5401 ttccaaacca acgatttttc tccttcttaa ccgtcacaac ctcttcaaaa accaaattgg
     5461 tctgctcttt ttcctggttc atcatcgggt aaagaagaaa gagactatag ataaccgcaa
     5521 caaaaatagc tagaatcaca aaaggattga gcataacgat gaaaaagaag agaatggttg
     5581 ccgctactaa aagaagatta ttcccctctt taccagtgta gtagcgaatc aaaagcaaaa
     5641 agaggaatag tatcagcaga aaacgcgaaa aatgctctga taccatcaaa atcagagctc
     5701 ctgtcagaag acaggcttcg ataaataaaa agattttaaa ttttctcata ggttcatcct
     5761 ctcccttcta ttttatcaca attcaaaaaa gtcacctcag tctgaggatg gaaaaaaggc
     5821 gctggttacg cctttttcat ctgatccttt gcttctttta attttccata aagaagatag
     5881 tctacttttt gtagatctgc tatggtggca cagttaaggg aacacataat caagcgtagg
     5941 tctgctttcc agccttggac aatgccaatc acttcttcaa ctgtgtaggt ttcaaccaat
     6001 tccagaacgg ttcgtgacaa tcccacagac ttagcaccaa aaaccaagca cttaatcata
     6061 tccagcggat tccgaacccc tccactaacc aagagttcga ccttatcttt ccattcttgg
     6121 gcattgagaa gggcctgcat ggtagactga ccccattgat tgaggtaatc acgctggcca
     6181 ctacgacggt tttcgatata ggcaaagctg gtgccaccac gacccgatag gtccactgta
     6241 cgaacaccga attcataggc tctttcgatt gtcttggcat ccattccaaa gcccacttcc
     6301 ttgaggacaa taggaacggg aatttgctcg ctataatctg ctagatgcga ttgccagctt
     6361 ctaaacttcc tttctccctc gggcatgagt aattcctgca tgacattgac atgcacttgc
     6421 aatagaacag gattcatctc ttctacagtc tgaagtccta actcgacagg cttgtccaat
     6481 ccaatattgg ttccaaggag gagattggga tgactagact tgacagaaaa agaatcatcc
     6541 gttggatttt tgagggctgc gctataagaa cccgttacaa ataaaatacc acaggattcc
     6601 gccacctgag ccagcttttg attgatttct cttcccttat tacttccacc agtcatggca
     6661 ttgatataaa aaggaaagtc ccactttcga ccagcaaact ctgtcgaaag atcgatttca
     6721 tccagattgt aaagaggcaa ggaagaatga atcagctcca cctcatcaaa gctattatag
     6781 gaacttttct gctcaagggc atagaggata tgctcgtcct tacgatttgt cgtcatgtcc
     6841 tatcctttct tgatataaga gctcaatccc cagatcggcc caacgatttt ttaaggtttc
     6901 ggttgattgc gcatcaaaac tcaaggcgat gccacagtca ccaccaccag caccactact
     6961 cttggcaacg gcctgcaaat cttgactggc ttctttcaac tgtctaagca aaggcgtgta
     7021 aatatctgta ctcaagcctt ctaaaagctt gctggctact tctacttgct cgataacttt
     7081 ttcggctttc ccctgctcca aggcttcgac caaagaaacc accgtttctt ttgaggaact
     7141 taaaaaattt tgattgatat tttgcttgat ttgctggacc atgtgactcg atacagccac
     7201 ttccttggtc catcccacta agaaatcaca ttctaaagtt ggtttcactt gtgagataaa
     7261 aaatccccaa tcacgctcca gaactgtcgc caagttttct tcttctaacc aagcagccac
     7321 cttctggcga tcaaatgact ggtagagaac caaatcctct gccacaatac aggcaaggtc
     7381 gcccatggaa ccattgtctc ctcgcttgag caagacagcg ctagtcagct tgaacaagag
     7441 ctcctgatca acagaaacat catacagagc cagtaaagcc ttgacaacca agacaacgac
     7501 gctgccacta gaacctagac caaacttttt cccttctcgt tccattttgc cacagatttc
     7561 tagggaaaaa ggtcttaaat tctgaccgcg aacagcgaag aagtctccca tcaaagcaat
     7621 cgtttcttga atcaagctgt agtcaggatt gggccttaag tccactgcga aatcaaacat
     7681 atctgaatag atacggtagc tgtcagaaaa agcaatatca gccctcatat agatgggaat
     7741 atcctttatc aaagctaact gccctggctc taaaatagca tattcacctg cccaatagag
     7801 ttttccgcaa gttttaacag caatcatctt gactcaaatc ctttgttttt gacacaatca
     7861 agcgataacg ctgaccgaaa atttctgata aatgctccaa gtctttctcc tgacagaaga
     7921 ccttaacatt gggaccagca tccatggtaa agtagcaggc ctctcctttc tcacgaagct
     7981 ggcgaacaaa gtccatagcc tcataagagg catccgtcag ataagaaaag gctggactag
     8041 cagtctttgt cgtagcatgc atagccaggg catttttctc cgttaattct ccaatcttgg
     8101 caaaatcatt ttccttgaga taaatcagca tatcctgata gtccttctca gactgacgaa
     8161 cccagtcgtc aaaagtcgtc gaggtttcca cacaaagttt catcccatca cggctagaga
     8221 ttggtttttt cttgtcctct agcaccaaca taatcatagc tagtttcaag tctgtctcta
     8281 cagggtaaat ttctccacta tccttatccc aggctcctag tggtccataa aaactccgag
     8341 aagaagagcc tgaggcaaac ttggcttcct gcgctaactg acttctatcc aatccaagct
     8401 tgaaataagc attacaagcc ttgaccaggg cggacaaacc actagaactt gaggacaggc
     8461 ccgctgccgt aggcatattg ttttgagtat cgatacggac aaagccctca ccagctggac
     8521 gataacggtc aataatctta ctcatcttgg catgctcgac ctcattttgt agctgaccat
     8581 tgatgtaaaa ttcgtcagct gttacattgg ctggtaaagg cgacaaggtc gtctctgtat
     8641 acatattttc caaagttaga gaaatactgc tagtagcagg caccatctct ttttcttttt
     8701 tctttcccca atatttgata atagcaatat ttgcgtagga acgtactgtt acaggctctc
     8761 tatccatgtc tgaacagctc ctttctcttc taatctttct gctagttctt gtgcgtgtgt
     8821 caaattggtt accaaggcta tgatacaacc tcctagccca ccaccgctca tcttggcacc
     8881 cagagcacca tggctaagag tcgtttcaac caaaaagtct gcctcagggc tactgactcc
     8941 aatttctttt aaatgtaaat gcgcttgact gaggatttgt cccagtcctt cagcatcttt
     9001 ttgtgaaatc gcaacttctg cttgctgggt taattctccc aaggcatgca aaaacggtag
     9061 ggcatccttg cccttatttt gaaccacttg gatggcttca cgagtatgac cataaacacc
     9121 cgtatcggca atcaccaaat aggcggataa atccatctca agttctgtaa atcctacgtt
     9181 cttgataaag cgaataggtt ggtcactgag acaggtctta gcatccaaac cactaggatt
     9241 catatgggca atcatttcag ctcgattgac caagatttct agtacatcat gaggcagaac
     9301 agcctgatag tagtcaaata ccgcacgaat ggccgctatg ctgatagccg ctgacgaacc
     9361 catcccccgt ttctcaggga tagccgagtc aatctcacaa cgaatgcagg cttctgtgat
     9421 atccaaatac tccagtgagg cataaaccgc catggacaag gtatcctcct cataaaggcg
     9481 ccaaggactc tctgcaggaa ctaccttaca ggtcacctcc acctccaaaa gaggcaggga
     9541 aatggcagga taaccgtaaa cgaccgcatg ttcccctatt aaaattatct tactatgtgc
     9601 ctggccgaca ccaacttttt ttgtcatttt ttccttttac tagacgaaaa aacgtcttat
     9661 ttttcataca aatattaatt ctttcctatc tattttatta tattttcaca aaaaaagcga
     9721 ttgtttccat tcacaatcgc ttctttcatt attgaaccca ttcgccatta tagttgacag
     9781 aatagccatc tacggtcgta ttcactgcca aggcacctga gctataagcg tagtaccatc
     9841 tgccattgac ctggaaccaa cctgtcgtca tagaacgacg aaagaaactc cataccatta
     9901 agtaaagagg aaagtcgtga gggagcatgc gccattgaca acctgtttta gtgacgtaca
     9961 aagtatcatt aacaagtact cgtttcggcc atttataggt gcggtgtttg gagaaatagg
    10021 gttcaatctt cgcccattct tgatcgttta aatcagtatc atatgcttta cgtatcataa
    10081 ctctagttta acattttttt gtgaatacag gttctaaata atcgaccacg aaaatttctt
    10141 aagtggaaaa cgccttatga agtatgctac gggaaagtta tgcacttaat ttgacaattc
    10201 aagatgtaaa aatatatact atagtatatt gaaactagaa tagtacacct ctacttctaa
    10261 aacattgtta gaaatcgatt tgactgtcct gatcaatttg tcctgttatt atttcatttt
    10321 actataatat ttgacaagtt atcctaaaag tattattatg ttgttgtgtt atagattgat
    10381 tgaatctacc taaaggatcc tattcaatta ctagaactat cacatactca aggtcagctc
    10441 acagatgagc aactattttg gttacaatat ctactaaatt taagtcaaac aaataattta
    10501 gtcaaaatta aaaaaataga ggaacataaa tatgattaca aaacagaatg taatagtgtt
    10561 ctacgatttt tactagataa aactgtaaat tctgaaggaa ggatcacttc ttcaacagaa
    10621 tttggaaatt tcgtaagtaa tttatcattc caacacggaa tagctggact actgtttcct
    10681 ctaaataaat tgtacccccc agaactggat tctaaaatac tctctatcat caagaaggca
    10741 gtgacaatta gaacgacaca cacatatgaa tatcaatact cactgctatt tggtgatgca
    10801 ggctatctat ggttactcct acatttattt tctatcagta aaaatcaata ctatctacaa
    10861 ttagcaaacg tcaccgctaa gaaattaata gagaattatg atactctaga ggaaatagac
    10921 tttgcattgg gaaaatctgg tgtcctatta ccattaataa aatactatca atttaccaat
    10981 gacaatactc ttaaaacttt catccacaat agtatatggg gaaatttatc attatttcct
    11041 acaaagagat acagccaaag aaagcatttt agactatagc tttgctcatg gatattgtga
    11101 aattgcatat gctttatttg cctattctaa agtcttagaa ccttctatgt tctataatga
    11161 tctccatata ttccatactg aattaaaaaa attattagaa aaagttactt ctaatactga
    11221 aaatttagga aatttacaac tttcttggtg caaaggaatt tccggaataa tcttatatct
    11281 ttgtatgtac gattgtgacg gaaacaaaga tattattagt aaatatcaag aatttgtttt
    11341 taaccatcat ctaaaaatga tgacaggata ttgccacgga ataactagct tactacaaac
    11401 cactgtctac aatcaaaaca aattactgat gaaaaaaatc caacaggtaa ttttagcatg
    11461 ttctgaacga gatgatcacg gtttactgat gtttcaagga gatagtggta aagcagattt
    11521 gtttgacttc ggaataggaa gcatggggta tattggtgtc tattaaataa taaattccca
    11581 ttcgatgtgc agacataagg agaaaagtat gaaattattt tggacaaaca acatatatag
    11641 acagttgctg ctaaacagct gtttttcatc attcggcgac agtattttct acctcgccat
    11701 tatcaattat gtggctcagt acaatttcgc tccgctagcg attttactga tttccatttc
    11761 agagatggtt cccctactat cgcaactctt tctcgggatt ctaggagatt ttcaagaaaa
    11821 tagagtcaaa cacgcactct ggattgccaa aatcaaaatc ctgctctacg ctattttgac
    11881 agtatttctc gtcttgtcgc ccttttcatt agtttcagtc attatgattg tcatcatcaa
    11941 cctcatctct gacaccttga gctacctgtc tgcctacatg atgaacgccc tctacatcag
    12001 tgtaattaag gacgacctgc atgatgccat ggggtttagg cagtctctga tgagggttgt
    12061 ccgcattgtc gccaatctgg ctggcgcatt ccttatcaat gttataagta ttcaaactat
    12121 ttcccttatc aacactctga cttttgtcat tgcctttttg ggcctgtatg ttattagaca
    12181 taccttgtat gaggttgaaa aaaggattga aatgtcacat acagcactga gttttaagaa
    12241 atattttcaa catcttaaac aatcgctggc tgtgctcctg aggttaaaag ataccgtcat
    12301 actactgttt ctgacgacca gtatgattgc catcttggat gtgtcccctc ggctgattgc
    12361 cctccgcttc atccaacaaa cactagcaca actaagcatt gggcaactcc tcgccctgct
    12421 ctccatcatc atgtcttgtg gagctatcct tggcaatatg accagcagta atctatttaa
    12481 aaatatccgt ttcacgcacc tcttggtttt ctgtgagatt tccctattgg ctctaataac
    12541 tagtatcctt tatcaagcct atatcgtaat tttcatgacc agtttcatca gttctacgat
    12601 tataggcatt ctcagccctc gcctacaagc agctgtcttt gcctatatcc ccagtgacaa
    12661 gatggggacg gtgggctctg ctctgagcac agtggacatt ctcgccccgt ccctgctctc
    12721 cctattagcc ctatccatag catcgggcgt ttcggtgcag ttagcattga tatttttgta
    12781 tcttattttg attgctctta tcttttgtca atggttagtc aagttcaaca ctcataacta
    12841 acaaaaaagc atgtgtagat ttcacatgct ttttaatctc cccaatcgtc aggtcaagta
    12901 caacaaagtc acttctttga ttaagcgagt gttctaatat aattataagc accctgtcat
    12961 taccgaaccc agtcgccatt ataattgaca gaatagccgt ctacggtcgt attcactgcc
    13021 aaagcacctg aaccataggc ataataccat ttgccattga cctggaacca acctgtcttc
    13081 atacctccat tacttgcatt taggtagtac caagttgaac catcttgata ccaaccagtt
    13141 gccattgctc ctgatgaacg gaggtagtac cacttgttac caaggtattg ccatcctgtt
    13201 ttcatatcac catttttatt atctaagtaa taccatttgc ctcgtacata tttccaatct
    13261 gttgccatag aaccagagga gccaaaataa taccattttc cgtttacttt ttgccaatct
    13321 gtaagcatct tacctgaagc atctaggtag taccatggag caggtttgct tctatcaatg
    13381 tcaatagtaa catgaaaatc ttgagtccaa cccttagcaa cttcaccaat tggtagtgga
    13441 ttgtaagaat catcgccaaa atttcctagc ttatttaaat aataccaatt gccgtcttca
    13501 taaatccagc ctgtctttac agcataatta ttatcaaaat aataagttct cttttcagca
    13561 gatagaggat attgttcacc gtatactttt cctgtatttt cagacgtttt tgcctctagt
    13621 acttgtttat ctgtttgttc tagcaaagca ccatcttgtc caaaatagta ccacttctcc
    13681 tgaaggccaa tttcattaac tggttggtta tcgaataaat tatcacgata acctgttcca
    13741 ggaatttcta agtattgcca accgacaacc atctctccaa tatcaccaaa atagtaagtt
    13801 ttaccgtcta ttttatgcca atagattgct ttatgatcat cttttacata atattttcta
    13861 ttatccttat caacaaatcg gccacctgtg gtattcgcaa ataccgtatt tgtagctagc
    13921 aaaccaaaga aaaagactgc tagtagaact tgcatcattt ttttcaaaag tttcatctat
    13981 atatcctcct aaaacgattg tagcaaagac ccgactgcat gtcaatatat aaaaactcct
    14041 caaaaaagca gttacacaac tgcaactgct tttctattct tgcatggtat atccaacacc
    14101 acgcacagtt ttaatgtagc ttttttgtcc tttaacatca agcttgctcc gtagatagcg
    14161 gatatagaca tctacgatat ttgtctcggt cgcactttca tacttccaaa cactttccaa
    14221 caattgctca cgagtcaata ctttcttgct tcccataagt gtcgccaaaa ggtcatactc
    14281 acggcgtgtc agagcaatca tctcttcacc acgataaacc gtgtgatgtt caacatctat
    14341 cctaagattg cggtaggtcc ttggaacttt catcagactg cagtgttgat caatgaagtc
    14401 ccgacctcgg aagatcgccg aaatacgcgc taccagattt tcgataagga ctggcttata
    14461 gatgtatgaa actgcaaaac gctgaacaac ttccagctct tcttgcaagt cttcccaatg
    14521 atctaaaatc atgatgactg aggcaggttt agttcggctc aatttttctg caaaatcctg
    14581 agccatcata tctcccagat taacgttcaa taaaatcaaa tcatagtctg tctgaagagc
    14641 catggagagg gctttttgcc cctcctctac cagatcaacc cgatactgct ctttctggag
    14701 ttccaaactt aaaaaatgag ctagatttcg ttctttctca agtaataaaa tccgtttccc
    14761 catggctgac ctacttattt ttcgtcatac caagagtagt ggaaggttcc ttctttgtct
    14821 ttacgttggt aagtgtgagc accaaagtag tcacgttgtg cttggatcaa gttagctgga
    14881 aggtcagctg aacggtagct atcaaagtaa gtaatagctg ctgagaaagt tggcactggc
    14941 acacctgctt gaaccgcaag agctacgata tcacgtactg cttgttggta cttagcagta
    15001 acatccaaga agtactcgtc caaaagaagg ttggcaagat ctgcatcgcg gttgtaagca
    15061 tctgtaatct tttgcaagaa acgagaacgg atgatacagc catcacgcca gatagatgcg
    15121 atatctgcaa atggcaagtt ccagttgttt tctttagagg ctacacgcaa ttgagcaaat
    15181 ccttgtgcgt atgaaatgat ttttgagaag taaagggctt gacggatctt ttcaatcaat
    15241 tcagccttgt ctccttcaaa gttgaaggca gctggttttg gaagcacctt gctagcatat
    15301 acacgttctt ctttgtaagt tgaaatgtag cgtgcaaaca ctgactcagt aatcagtgac
    15361 aatggtacac caaggtcaag agatgattgg ctagtccatt taccagttcc cttgttacct
    15421 gcagcatcaa ggatgtagtc tacgattggt ccatcttggc cttcatcgtc tttacggctc
    15481 aagatatcag ctgtgatttc gatcaagtag ctatccaatt cacccttgtt ccactcagta
    15541 aagatttcag ccatatcctc tgcagaaaga cctagcaagt gttgcatcaa gtcataactt
    15601 tctgcgatca attgcatatc accgtactcg ataccgttgt gaaccatttt cacatagtga
    15661 ccagctccat caggaccgat ataagtcaca catggcttgc catcttctgg tgctttagct
    15721 gagatttctt caagaacatc cgaaaccaat tcgtaggcct ctttttgtcc accaggcatg
    15781 atagaaggac cttcaagggc acctttttca ccaccagaaa ctccagtacc gataaagttg
    15841 atacctgagt ttgccaattc ttcattacga cggatggtat ctttgtagaa agtgtttcct
    15901 ccgtcaatca agatatcacc tttgtcaagg tgtggaagaa gggcttggat agtagcatct
    15961 gtaccaggtc cagcttgaac catcagcatg atacgacgag gtttttcgat tgagtttaca
    16021 aaactttcaa cgtcatagct tggtacaaaa ttcttttcag gatggcaagc aatcacatct
    16081 tccgtttttt ctttactacg gttgtagata gcaactgtgt aaccacgtga ttcaatatta
    16141 agggcaaggt tacgacccat tacggccata cctacgacac caaagttagc ttttgtcatt
    16201 tgacactcct cttgtttcat ttgttttatt ttatcatttt tacttttgaa aagaaagaat
    16261 tttgtaacga ctgcttagta atccaagtca tccgcatgac cagcgccatt tccgacaaag
    16321 tagcctgtct tacagttaag ggtaaagaga taggttccat ctggcttgta gaggttgtaa
    16381 taaccattgc cgttaacgat attgacacgt tcaaggatat attggtctcc agtgatatag
    16441 ccacgtgaac gtgaagttgc tagaatttgt tccaagacac catccgcaaa atcccaggca
    16501 gagttattac tatcatcaat agcagactga ttataggcaa cacgactggc acttctttga
    16561 acagcaaccc ctgcactcga gagacccata ttgacttcac tgcgactact tctagtctca
    16621 tttgaactac ttggttttgg ctcactagtc gtatttgagc ttgcttgact agagcttgag
    16681 ctgctagttt gacttgaact tgagctagaa gtacttgttt gctggctctt accaagactg
    16741 atagccttat ctagcacttt atcaagctcc gtattcccag ttttaatatc tgtaaattta
    16801 gcatccgatt tggctttggc attggtatcc aacacaccat ccacaatagc tggtttttca
    16861 aattgtgcat tgacatcttg aatggcctta atttgcgtta ctagactatc atatttagat
    16921 ttggcaagcg tatgttcacg actaccttcc agcttatcaa gtaaagtctt gagttgactc
    16981 agtttatcaa actggctatt tttcaaagcc gttttattgc tatctgtgta aaaggcgtca
    17041 taaagtgtat taaaatcatc cacatccgat tgattggctg tagttgattg agaagtttca
    17101 atttccttag tcgaacgagc cacttgacgg tagacataat aagcactgac acaaataatt
    17161 actgatacaa gcgccaaaac ggtcaaaata aagccttttt tacttttctt ttctgagtcc
    17221 tcttgatcca gacgagaaag gttttgctcc tcttccactt cttcagtcat ttctgttgga
    17281 ttttcatcat ctagcaatag aggatccaag ccttgctcct catcgtccag aggcaagggt
    17341 agtaagatgt cttcagaaga tggaacttcc tccgaagaag cttctgactt ctctacagcc
    17401 tcacgcatct cttgaattaa atcatccaga ctctgagttt caacgaactc ctcttttttg
    17461 tattgacgag tcgcaaactt atccgcctca atttcatctc tgtgttgctt aacatacttg
    17521 tccaaaatgg aatcctcagg caagactcct gcttccactt cttcattttt acgaatagct
    17581 tgaccaactg ttagctcttt tgcttcatca aaatcaaatt gcggttcttg accttctttt
    17641 ttatgacgat ttcgtctttt tttactcatg agtatccctt tctattttac ctcttgccgt
    17701 ttgacacgct gaccaaaata ttgatataga tccactttca aggttccgtt gtataactta
    17761 cgcttcttat ctgcttggct accatacttg ctttcaaaag cttcatcact agtcaggata
    17821 aatttgctcc aagttttcag cggtgcaaat acttgcccca tctcagcata gagcttggtc
    17881 acccctgcat catctgacaa acgttcacca taaggcggat tggaaatgat tactccattg
    17941 attttatcgg aacataaatc ctgcacgcgc atctgcttaa aagtaatgtc tcctgcaaca
    18001 ccagctacct gagcattggc cttagcaatt tccaccatgc gagcatcaat atcacagccc
    18061 atgatatcca gctcaagctc acggtctact tttttagccg cttctgtgcg cacttcttga
    18121 atcaagcgat cgctgatcca gttccattcc tcaaatgcaa aagaacgacg aagacctggc
    18181 gccatctttc tagcaatcat aactgcctca atacagaaag tccccgaacc acaggtcgga
    18241 tcaatcaaag gcttgtctgg ataccagtta gaaagttgta aaatggctgc tgccatattt
    18301 tccttgatag gagcgccacc tttttcggta cgataaccac gtttaaagag gctagacccg
    18361 gtcgtatcaa tcatgacagt tgccacatct ttgagaatag agacctcaat cttaaactct
    18421 ggaccattct ccatcagagg aaccccttct gggcgagcat agtgtttctg caatttcttg
    18481 acaacagctt tcttagaaat agcctgaaca ctgggctcat tgtgaagttt ggacttaaca
    18541 catttagctt ttgaaatcgg gaaccgagct ccaagtggta aataattttc ccaatctaaa
    18601 gcgaaaactc cctgaaatag ctcttcaaaa gtcttagctg ggaacgttcc tacgataatt
    18661 ttgatacgat ctgctgcccg aagccaaagg ttggtttcga taatagctct cacgtctcct
    18721 tgaaaacgaa cacgtccatt ttcaacctga caatcgtagc ccaactctcg catttcacga
    18781 ccaacgacag cctcaagccc tgctgccaca gttgcaatta aattaaattc ttttttcatg
    18841 ttacagtctt gcaagacctt tctatatgtc cactttaaaa aatgaggttg agaaaatttc
    18901 tcagccccaa cctatatgca attttctata agccatgttt tgttccagaa gtgactagga
    18961 ccacttcctt cgataatcat ctgtctacca ctaacagctc tagctgatag cagtcagaat
    19021 actacgttcg tttccgcgta ctccatgccc cgaccaaaat ttgggttgct agcttgaggg
    19081 gtttaccgcg ttccactctc tctgtttcca gaaagacttc gtcactgtgg cactttcaag
    19141 cctactctgg cctatccaag gacttagcca tttcaactgc cgtaacgatt tctcgtccct
    19201 aggcttatgg tttcgcctag cacaaacact acaggcatca cagcctgtgc tagcatggac
    19261 tttcctcatg agaagcaatt ctcctcacgc gattatccaa aaattgcaca tctcaaataa
    19321 ctacttaaaa atctgagtta tctaaaattt gtttaccaaa aacttctttt tccaatctat
    19381 tcaggcgttt caaaatatca aaattcgtca tagaacttgt aattgccgct tcaaggggtt
    19441 ctgcttgaac tggtgaaggt ttcggtttac gagttaattc ttccttcaaa tccgcaattt
    19501 cctgacgaag tgacttgacc aaggcagcat aggtttcata gtccttgatg acatcgtcta
    19561 aaaactcgtc aacttctact ttattatagc cacggacttc acgtccaaac tcttgttcaa
    19621 aaatatcttt cgctgaaaaa ataatacttg ccatgtctct ctccattctc gcttgctagt
    19681 attattatat aaaaaaaggc aaacaaaaat caaggtcaaa gcttcaattt tcggaaaaat
    19741 tttcagcaag ttcatttaat tgatcaaatg ttaatctctt tataaaatag tcctcttgat
    19801 ttttcatctt ttggtaaaaa taagctagtt ttgtttcatt ttcttcatca taaaaaagat
    19861 aggaactagt cgtgttttcc agcaaaaact gctggtaatc tcttaactgc cccttgtgtt
    19921 catagcgagg ataggcatat ttgacaaagt ctacctgctt aaagcgactc agtttcatct
    19981 gattgccttc attccaattt tccccatggg tttcaaaagc aaaaatggtg gccaactgga
    20041 aaccgtattc ggttttcatc tcctgagcaa cctctaaaac ccaatattca aaccccaaac
    20101 tccctgtaaa cacaagccaa gacaccccat ctgctgccat agcctctaaa tctttacgta
    20161 tcgctttttt aatcaattta agacgaggat ccttatcaga aaataaaccc aaatcaaaag
    20221 cagaatagcc taaaaccaaa gctgtagcca tttttaaccc tttctgtgca aattatggta
    20281 taataaagtg atgttattgt accaataagg agaattatgg tcaactatcc acataaagtt
    20341 tcatcacaaa aaagacaaac atctctttct caacccaaaa atttcgcaaa tcgaggaatg
    20401 tcttttgaaa agatgatcaa tgctaccaac gactactatt tgtctcaagg cttggctgtt
    20461 atacataaga aaccaactcc tattcaaatc gtacaagtgg actatccaca acgaagtcgt
    20521 gccaagattg ttgaagccta ttttcgacaa gcttcaacga cggactattc tggcgtttat
    20581 aatggatatt acatcgactt tgaagtcaag gaaacaaaac aaaaacgtgc gattccgatg
    20641 aaaaattttc atccacatca gattcagcat atggaacaag tccttgccca acaaggaatc
    20701 tgctttgtcc ttcttcactt ttcttctcag caagaaacct acttattgcc ggcattcgat
    20761 ttgattcgct tctatcatca agataaggga caaaaatcaa tgccacttga atatattcga
    20821 gaatatggat atgaaatcaa ggctggtgcc ttccctcaaa ttccttatct caatgttatc
    20881 aaagaacatt tattaggtgg taaaacaaga tgaacaaacc aacgattctg cgcctaatca
    20941 agtatctgag cattagcttc ttaagcttgg ttatcgcagc cattgtctta ggcggaggag
    21001 tttttttcta ctatgttagc aaggctccta gcctatccga gagtaaacta gttgcaacaa
    21061 cttctagtaa aatctacgac aataaaaatc aactcattgc tgacttgggt tctgaacgcc
    21121 gcgtcaatgc ccaagctaat gatattccca cagatttggt taaggcaatc gtttctatcg
    21181 aagaccatcg cttcttcgac cacaggggga ttgataccat ccgtatcctg ggagctttct
    21241 tgcgcaatct gcaaagcaat tccctccaag gtggatcaac tctcactcaa cagttgatta
    21301 agttgactta cttttcaact tcgacttccg accagactat ttctcgtaag gctcaggaag
    21361 cttggttagc gattcagtta gaacaaaaag caaccaagca agaaatcttg acctactata
    21421 taaataaggt ctacatgtct aatgggaact atggaatgca gacagcagct caaaactact
    21481 atggtaaaga cctcaataat ttaagtttac ctcagttagc cttgctggct ggaatgcctc
    21541 aggcaccaaa ccaatatgac ccctattcac atccagaagc agcccaagac cgccgaaact
    21601 tggtcttatc tgaaatgaaa aatcaaggct acatctctgc tgaacagtat gagaaagcag
    21661 tcaatacacc aattactgat ggactacaaa gtctcaaatc agcaagtaat taccctgctt
    21721 acatggataa ttacctcaag gaagtcatca atcaagttga agaagaaaca ggctataacc
    21781 tgctcacaac tgggatggat gtctacacaa atgtagacca agaagctcaa aaacatctgt
    21841 gggatattta caatacagac gaatacgttg cctatccaga cgatgaattg caagtcgctt
    21901 ctaccattgt tgatgtttct aacgggaaag ttattgctca gttaggttct cgtcaccaat
    21961 caagcaatgt ttccttcgga atcaaccaag ctgttgaaac caaccgtgac tggggttctg
    22021 ccatgaagcc aatcacagac tatgctcctg ccttagagta tgacatctac gactcaactg
    22081 cttcgattgt acatgatgtt ccttataact atccaggtac tgatactccc ctctacaact
    22141 gggataaagt ctactttgga aatattacaa tccagtatgc acttcaacag tcacgtaatg
    22201 tcacagccgt tgagactttg aataaggtcg gtctagatag agctaaaacc tttcttaatg
    22261 gtcttggtat cgactatcca agcatgcatt atgcaaacgc catttcaagt aatacgactg
    22321 agtcaaacaa aaagtacgga gcaagtagtg agaaaatggc tgctgcttac gctgcttttg
    22381 ctaacggtgg tatctaccat aaaccaatgt atatcaacaa aatcgtcttt agcgatggta
    22441 gctcaaaaga atacgctgat cctggtactc gtgccatgaa agagacgacc gcctatatga
    22501 tgacagaaat gatgaagact gtcttggcat acggaacggg tcgtggtgct tatctccctt
    22561 ggctacctca agctggtaag actggtacat caaactatac agatgatgaa attgaaaact
    22621 acatcaaaaa tactggttat gtagctccag acgaaatgtt tgttggttat actcgcaaat
    22681 attcaatggc ggtatggaca ggttactcaa accgcctgac tcctatcgtt ggtgatggct
    22741 tctatgttgc agctaaggtt taccgttcaa tgatgactta tctgtctgag gataacaacc
    22801 ctggcgactg gactatgcca gaaggtctct atcgaagtgg tgagttcgtc tttaaaaaag
    22861 gtgctcgttc tgcatggact gctcctgctc cgcaacaggc cccaacacca gaaagttcga
    22921 gctcgacatc agaaagttca acttcacagt caagctcaac tactccaagc acgaataata
    22981 gtgcaaacaa taataccaat aaccagcaac caaatacaac gcctggtcaa caaaaccaga
    23041 accaaaatca gaatcctcaa ccagcacaac cataacattt atcacccaga tttttctggg
    23101 tgattttttc atagcactat tgcatttata tgcttaacaa aagcctgaga agatgtcttc
    23161 tcaggctttt tctgtacttt aaacctcatt gggaaagata ggaaacggat ttcgtaatct
    23221 tgttaagagg ttttactaaa tactagtctt tctttgtttt tgctacaaag agagcagata
    23281 gggctaggct aactcctgct aggaagaggg ctgtgtcaga ttgactctca cctgttgctg
    23341 gcaagatttg ttcaggtgtt tctggtctag ctatttcttg cttataatct ggcgtcttac
    23401 cttgctcgga agctaaagag ctaagtttaa actcaggttt ctctacagtt ggagcatctg
    23461 gtttcgtagc agaatctttt aattggttga gataatctgc aaagtattcc accattcttt
    23521 ccgtcaagag atggttatcc gtcgcatatt tcatgcttgc ctgaacgcta gctacttcct
    23581 cttgattgtc tttgtctgtt aatttctgag ccttagccaa agctgcttca tagcctgaca
    23641 agtcaagagg tgtttctgct acctgtggac gagtaaagat aagttccgct gcagattggt
    23701 atttatcgcc accatctccg taagtcttag tacctgtaag gacaattttc ttagccttaa
    23761 ttgtcttacc aaaatcaatg tcttttggct tattgttatc tggccaatca gttgcagtaa
    23821 aggtatgctc cttgccagac tcatctgtca caacaagttt cacatcacgc aagttaccat
    23881 ttgaacccga tccacgtgga acgtaacgaa gtccagtgat ttcagttggt tctttcaaga
    23941 ccatggttgc aggcttgcct acatctccac cgccccatga tgtatgccat aaactagata
    24001 agtttccatc aaaggcattt gcaagacctt cttgagcctg agcaggagct gtaagacttg
    24061 caaagtcttc tgctaccaaa gccgttttct tctgaaccaa agcattcttc aaggattcaa
    24121 tcttggcaat ctctgcacgc gcttcttcca cactgatatc atcatcggcc tgactgaggt
    24181 taaagaccgc ctctttcaaa gcatccatag actctttggt gtagttagtc atggcaaccg
    24241 ttggcaagta gttcttcaga gcattttctg tcaacatctt acctgttagg gtaatttctt
    24301 cgatttgaag attatccatc atgaagtcgt tataaccacg gaagttggca tttccaccag
    24361 aatcaccacg agtattactt gcattgccag ttgagtagat acctacccaa gtatcccctg
    24421 tttctgcacc tgtcacaagg aaggttgcct tcttggcttt cttagaatct gtccaagtat
    24481 ttggcaattc atgcatttcc aagttgcttg cttgagtgcc acgacgacct gactggaatt
    24541 ctcccttacc gactacaaaa gcataggtat tgtctgaacc tgcttcgtat tcaaaggtta
    24601 cacggtaggt cttacctgct tcaaaacgga agttttgcgg aatagtttgg taaaccaagt
    24661 tacgacggct cactagtcca tttgtcttga gtgaccaatt tccttcgata acatcatcga
    24721 ctttcttacc attccaacca cgttgtgtat atggatcgtg tttttcagac aagtgagtgc
    24781 ggttatcttc aacaccttca acaccaccca ctacaaatgg gaagataccc tgagcaacat
    24841 tttcaaagtc ttgcttgaag gtgcctttac ctgtatcatg cttgtctccg tacatgcttg
    24901 aattgttttc aaaggtacga atttcatcaa agtaagttgc ttgatcacca gcttcacgac
    24961 tcaatgtcag agtaacattt gagacgtccg atccagttgt aaagaaggcg tacatgtttt
    25021 ggaagtaact tgtatcgtca actgtagcat tgtcacgacg tgtattgtgg gcgtaggctt
    25081 ttacatagtt gagggcgaga gacttattgg tataagtagt cacttctttt tcaccagtat
    25141 tcacagtgat acttgccttg gcattactac ggttatcgac accgacataa acggcatact
    25201 tggtatttgg tttcaagcca gttaatttct gagtgagact aactttttct ttgtttcctt
    25261 gaatacgaag catatcgttt gccccttgag acttgacaat ttctgcctta gaagcatcgc
    25321 ctgaaatggt ccaatgtttc aaggtaccac tgttaaatcc ttggtcatag atgtgcatgc
    25381 cttcactcca tgacatttca ggattggttt gttttgaacg atagagaacg tatggttgat
    25441 ttgctagaag atctagggta attttaccat cttttacagt tagttcttgc tcttctgtct
    25501 taccttggtc agttagcttg taaaggtaaa ccttgctctt tgcccaatcg cttggaaggg
    25561 tccaagttgt tgcaccggcc tgcgtattga agtagtacat cttttcctta tcagtagaaa
    25621 gtttcttacc atttgcatcc cagttccaag gagtcaagta agctgaacca tcttggatca
    25681 cacgtccgtt gagcgttact gtacgttcgc gatattgtgg gctattgaca tcatttgact
    25741 tacgagttac aactacttta ttattgtcag tatctaccaa ttccactcgc atttctggag
    25801 tccatttata ggtgctaccg ttatcggtca tagtcaccgg tgtaccattt tcccatttac
    25861 ttacagtgaa gtgttggaag tacttagtca tgacgtcatg agcaaagagg ttagtcacgt
    25921 agccattgta gtcacttctt ccttgccagc cttcaaagtc tttcatgctg tagccaccta
    25981 gcagtggata gttggctgca ccaccataac ttctgtagtc cccaacccaa gcatcttttt
    26041 ggtggttacg gataaagcgg gtgatggcac tgttgatacc tttattggtg tagccaccgt
    26101 aggtcaagtc agctgcccag tgatggaagg tagagtcgta ctcaccacca tggccccact
    26161 cgatcgcaaa gcgccagcct tgtttgttaa tttctttagc aagaacgtgg gtagcccagg
    26221 caccgttatc acctgattga ccattacccc aaacgtccac atagataaag tcgagaccgt
    26281 caccaagttt tttcttcaaa tcttcccaac gtgccaaacg accatgagct aggtcatagg
    26341 cagcatcaat gttgatacct tgatctagcc agttccaacc atagctataa cttccatctg
    26401 gattcttacg gagaattttt tcattgaagt atttagactc aggataagtt tctgaagcgt
    26461 taacgtggat acctagatga gctccatatt tcttagcctt ctcaattagg gtcttgaagt
    26521 cttcgacacc accgatacgc ttaccaatat cagcatagtt caagtgacca gagtcatggc
    26581 cttcgctacc atatccttta aggagaacac cttgcccaag accatctgta tggagattga
    26641 ttttcttgat accatccaag gtcataagga atggattttg tgcttgagaa ccaaagttca
    26701 tcgcgatacg gtaagctgtg atatccttaa ctttttccca accttgagga ttgttcataa
    26761 tgctacgata agcaatggca ccatcttgcc aatcaacgtt cttgtctgca ttggcatctt
    26821 cagtgataac aaccttagca cttggaagtt ccttcgtgta ttctgggaaa acaatgccct
    26881 tataagcttt ttcccattgc cattcagagc tgtggattcc tacatagttg gcatttccga
    26941 ctgtttcttt ataagctgtc aaacgagtcc agtcattcga accaccacca tagctgtttt
    27001 gagagttact ccaaacacca gcagcaagct tatctgtaga aacaaatcca tacatgtaac
    27061 ccttagccaa atccttcatt ggattggtta catcgatatg atcatctccg ctgacatgcg
    27121 tattgtttga catggttgcc ccatcaaact tagcaccagt ttgatcacta gaaacagaga
    27181 ctaaagcatt gccgaggaaa ctaatagaag aaagtagttt tctttcgtca tcaatctttt
    27241 gacctggagt gacttgattg tggttgacaa tcttggtcac atcaaagtgc aattgattgt
    27301 ccacaacttg caagcgtact gtcatttccg cattgattaa gtgagcatca tcgcgaatct
    27361 tcatcaagta ctctgctgtt gtctcattga ttttcttata agtgacttca ggggtgattc
    27421 ggtggttatt gataaagact tggttgaact gttgcacctg tcctggcaaa gtatgtccat
    27481 tcaaggtgta ttccttgaca cgagggaagg cttggtcaat tactgcctta agtaccttag
    27541 actggatcgt atcataagtc accttgctat cgtcaacaac cggacctgtt tctttctggg
    27601 caggagtatc atccgctttt acgccttctt gattgtctgt tttaacgctg acaaccgtac
    27661 ggtcattgcc ataagagccc gccttgagaa ggatcttctt ctcattttta agatggtcat
    27721 tgaccgcagc tggtagagtc actgtgtcaa agagattgac atcgttattg ctggcattta
    27781 gctgaccgtc tgacttgaga gtgatagaga gacggtttgt tgatcctgtt tcaggagcag
    27841 caacacgact acctctatac caagtgctag ttgttggaga tttatactcc cagaaccagc
    27901 catccttgtc ataaccgaca aaaacattat tattggtatc tttaaatttc aagaagacac
    27961 caaagcgtga tttgcccttt tcagaatcat ctttgaaggt taaatcaaca gttgcatttc
    28021 cattggcatc aacggtcaag cccttctttt caaacagggc tggtttacct gcgttatcat
    28081 tttgagcagt tgaggatagt tggttgtagc ggacaccttt ttcttctcgg atagtgactg
    28141 ttccctgttg ttcttttttc tctaccgttt gccattcagg ggttaccgtc ttaggtgttt
    28201 caggtttagc agctgcaggt ttatcctctt ttggtttttc ttcagccggt ttttcttttt
    28261 caagtgctaa tagttcttct tctgtcttag gtccatctgt aacttctgga gaaccttggt
    28321 cttctcccac cttaggcgct tcaaaatcac gcccatcatt ctcttttgct gttgcaagag
    28381 cagtagctaa atcagctggt aagttcgccg tggaaccaga ctgcacgcta tctgcaagaa
    28441 ccggacttgt cccaaagaat gcagctccaa tcataacaga agcaacacct aatgaaaatt
    28501 tccgaatact atatttacaa cgtttttcaa ataatccttt attcataaac ttctaaatcc
    28561 tttcattttt gagcaagcgt ttacattttc tttttaaaaa atactccttc ctctgaaagt
    28621 gcaatgctta accctgataa ataaaaaata attatacttt taatataaca aataatagct
    28681 gagaaagcaa taggaaacaa gtaaaattaa caaaaatttt ctctattctg acaaaaagag
    28741 gctccaactt ttgggggtca gtacatttag aatctttctt tacaaatgta aaaaaggatt
    28801 cagcattcaa gagaaatact aaatcctttc ttatattttg caacagttat ttcacatgtt
    28861 ttgcgagatc ttcttgagcc tttttattag actcttcttt ttctttcatc catttttcct
    28921 gagctttttg gtattcatct acagtgactg ccttgtcttg aagttccaag tatttataca
    28981 agactggttc acttgtgcct ttatttcctg acaatgcaaa tggtattgta aatggtacca
    29041 tcttagacaa gattggacgc cctgtacgag atgtagttgg aataatcaaa gcactatctg
    29101 tcaaccaagc ttgggctgca gcgtatttat catagcgttt agcaacatct gtagcctcat
    29161 caccagcctc agtaaccaat ttttcgtagt catatagacc tactttttta gcagctacat
    29221 tatcttcccc tgagtcaaac cctaaatatg ttttagtact ttctcctaca gatggtttga
    29281 tgatatcaag gtaggttgat ggatcggcaa agtctggacc ccaaccgaca ttatctgata
    29341 aatcccagtc ttcgccagca gcattttcag caaaatatgt aatattgttt acttcgtctt
    29401 tttgtagttg ttggatatca ataatgacat tatcagctcc taaagttgct tccaaggatt
    29461 gtttcataga ttggacgcgc tgaacttttg tagttgctgt ctggtcaact ggcatatcca
    29521 aatgaattgg gaaagtcaca ccttctgctt gtaaggctga tttagcttta gcaaattcag
    29581 ccttggcttt ttctggattg taaagaccat cctgagaatc tgcaagatta acatccttcc
    29641 attcatcccc ataagtgacc aatttctctt tgaccatatc gccaaagttt ttaccatctg
    29701 cttgaacaaa tgttggtgga acaaagatat tacgtaagat tttgcttgct ccagtttgtc
    29761 cattcaactg agaggcatag gctgtacgat caaaaccaaa ggcaatagcc tgacggaaat
    29821 ccttgtttaa gagagccttt ttagtcgatg ccttttgttc gtcgctggtc ttagatgtgt
    29881 atttatagga ctgacggtca atatttgtac caactaaata cgtaatagag tcttgttgag
    29941 tatagacaat attgtccttc atactcttct caagctctgc gaaacttgca cttgttggat
    30001 agagacgagc tgctgtaagg ctaccatctt taaagttttc tgcaggtttg ctggtatctt
    30061 gaccatccca gaatgacaat ttaactttgt caatatgcac attgtcctta tcccagtagt
    30121 tcggattttt cgcaaattca acagaagatt tggtcacaat ggatttcaac aaataaggac
    30181 cgttatacaa gagactactt ggatccgtag ctttggcaaa atcatcccct tttgaattca
    30241 aaaactcttc attaactggc gcaagcacac ccatggttgt cttagaattc caaaagcttt
    30301 ctggtttgtt caaagtgtac tgaactgtct gttcatccag agccttaatt cctacttgtg
    30361 agaaatcttt gatttcccct tttacatagg catccaaccc tttgattgat tcttgaacaa
    30421 ggtaaagagc atctgatttt ttatcagcag catattttag tcctgttaca aagtcttgag
    30481 ctttgactgc cgcgtattct tcaccttcag aagtatacca ttttgcatcc ttacggatag
    30541 tataagtgta agtcaatcca tccttggata cagaccaatc ctcagccata gacggcacaa
    30601 agttcccgta gcgatcattt tctagcaaac catcaaccac gttactggta atatttgctg
    30661 tcgcagcctt agcagttgtc aaatagttga ggttatcagg gtctgtctca taaatgtatg
    30721 agaatgtctt ctcaccttta gtgcttgaac ctgatccaga gcatgcagct aaagtagtcg
    30781 ccgccaataa tgtcacgccc gcaagggcaa atagttttga acttttcatc attttctcct
    30841 ttaaaacttt ctctccatta taaactcttt tcagaaagat gtcaacagaa ttttcagaat
    30901 ttttgaaaat tatttttcaa acaacatctt tgcaaaaaat atgaatatca tttaaaaatc
    30961 cctcaactat atcacatagt caaggaattt ttaatactat ttctaaataa taactggtag
    31021 tcagttttac ttgtttatac tcttcgaaaa tctcttcaaa ccgcgtcagc ttccatctgc
    31081 aacctcaaaa cagtattttg agcaacctgt ggctagcttc ctagtttgct ctttgatttt
    31141 cattgagtat taatctaact catttctcac gcactgcaaa gctgctccaa ttacttggtg
    31201 catatcgtaa taacgatagt gtcctaagcg accaccaaag ataacattcc cttgctcatc
    31261 agcaagtttt ttatacgatt tatacaaatg attattacga tcattattaa ctggataata
    31321 aggctcatca cctttttccc atgttttaga atgttcttta gtaatgatag tctttgcttg
    31381 actcccaaac tcaaaatgtt tgtgttcaat aatgcgagta tatgggattt ctgcatccgt
    31441 atagttcaca actgcatttc cttggtaatt ttccatatcc aaggtctcat tttcaaaacg
    31501 aagactacgg tactctagtt cgcccaactt atagtcaaag aattcatcaa tcataccagt
    31561 aaagacaatc ttaggaaaat ctttcagata ttgctcttta ttcacaaaga aatcaacatt
    31621 tgtttctaca tcaatatttt catgatccaa catttttcaa ctatttgagt gtatccacca
    31681 attggaatcc cttgataggt atcgttaaaa tagttgttat cataggtcag gcgtactggc
    31741 aaacaataat aaaggctgga agttcagtag ttggtttgcc ccactgtttc tctgtatagt
    31801 ctttgattaa tttttcgtag atgtctgtac ctacaagaga aatcgcctgt tcttccaaat
    31861 tttcaggagt tttaccattt aaaatagcac gttgttcatc aatcttagct tgtgcttctg
    31921 ctggcgtcac aactccccag agtttattga aggtattcat attaaaagga aggttataaa
    31981 tctcaccctt atagtttgca acaggagaat tggtataacg gttaaagtct gcaaactgat
    32041 ttacataatc ccagatctcc ttatcagaag tatggaagat atgagcacca tattgatgaa
    32101 cttgaattcc ttcctcttca cgagtataga tattacccgc gatatgattt catttttcaa
    32161 taacttttac tttttttcct tttaagactg cttcatgggc aaagactgca ccaacaacaa
    32221 gataatcgta catcttaagc tcctttggag ttcattctct gcctctttta ttagactaga
    32281 aaatcattct actacttatc tcacttcttg tttgtaaaat tcttgcaatg catcttgcca
    32341 agttggaata acaaatccag tagctttggc tttggccagg ctcatcgttg agtttagcgg
    32401 acgtttagct ttggctggaa attgactgga atctactggc ttgacttcga catctgtatc
    32461 tttcaaaatt tcaactgcaa aatcatacca tgttgtatct tctgtcgcat catttgacaa
    32521 atgataataa ccaaattcct tacgattttc agctaggtag gtcatgaact cagccaaggt
    32581 acgagtccaa gtcggacgac cgtactggtc atttacaact gttaaagtct tatgagtttt
    32641 cgcaagattt tgcatggtaa aaacgaagtt tttgccataa tttccaaata cccaggcagt
    32701 acggataata tagaaattag acacatgctt ctcaactaac tcttccccca tacgcttagt
    32761 gcgtccatat tctgtctgtg gatctggtcg gtcatcaact tcccactctt gtccaactgg
    32821 tttcttaccg tcaaagacat agtccgtaga aatataaact agagttgcac catgcttttc
    32881 agatgctttt gcgatatttt ttgtccccgt cacattgatg gcgaagtcca actcttttcc
    32941 ttcatcctct gctgcatcaa cagcggtgta ggctgcacaa tggtagacta aagtcggttt
    33001 cacctcttca aaaactttct caaccatttc ttcattggta atgtccatct tagccacatc
    33061 tactgccacg tattcttcat tacgttcatc caataaatag cgaagttccg ttcctaattg
    33121 gccatttgcc cctgtaatta aaatcatctc tagacctttc taatatgtaa ctcttcccaa
    33181 tatagcaata aaaagcagct atttcctgct ttttatactg taataatctc ctgagtctta
    33241 gcataattgg cttcaacagc ttctttttct gttttccacc attcttggtt atctgtatac
    33301 cacttgattg ttgccttgag cccagcttca aagttggtaa attcaggttt ccaccccaac
    33361 tcatcacgga gcttgctagc atcaatcgca tagcgaaggt catgtcctgc acggtcagtc
    33421 acatgatcat aggcatccgc agcttgtccc atttccttaa ggataagttc caaaacttcc
    33481 ttattgttct tctcaccatc agccccaatc aagtaggttt caccgatttg cccttttgtc
    33541 aagattgtcc aaactcctga agaatggtca ttggtatgaa tccagtcacg aacgttttta
    33601 ccttcaccgt aaagttttgg cttgatacca cttaggatgt tagtaatctg acgtgggatg
    33661 aatttttcga tatgttgata aggaccgtag ttatttgaac agttggaaat cgttgccttg
    33721 actccaaaag aacgcaccca ggctttgaca atcaaatctg aggctgcctt ggttgatgag
    33781 taaggcgagc ttggattgta cttggtttca gccgtaaatt tctcacccgg cccttctcca
    33841 tgacctggca aatcttcgcg taaagggaga tctccataaa cttcatctgt cgatacatgg
    33901 tggaagcgaa tatcatactt acgagcagct tctaaaagag tataggttcc gatgaagtta
    33961 gtatgaataa atggcgatgg atcattgagc gaattatcat tgtggctttc cgctgcataa
    34021 tgaacgatag catctgcttg agcagccaac ttgtctacca actccgcatc agcaatgtca
    34081 ccaacaacta actcaacacg attacctaaa atttcctcaa tattcgcgcg gtttccagca
    34141 taagtcaact tatctaggac tgtcacgtga acatctggaa agttctcgta aacataatgg
    34201 acaaagttag aaccgataaa gccagctcca cctgtcacga taatattttt gtattcagtc
    34261 atattctttc cttattccaa atcttctttt ttcaaaggct tcacgtcctt aagtagggga
    34321 tgatgtttat ctgcttctga aacctctgct tctgcaatat tttcccattc aataccaagg
    34381 cttggatcag cgtagttcac aaaggcatac ttgggtttga gttcaagagc ccagtaatca
    34441 ttgaccagat agctatatga cactgtatct gataaaactt ggaagccatt agctacgcct
    34501 cgaggaacaa agattccctt actcgcatca atcactgtct gataggtatt cccaaaggtt
    34561 tcaccctcgc gtagatcaac ccaagaaccc agaactttcc ctccatctgc tacagagatg
    34621 tacttatccc aaggctctgc gtggaggcct cgaaggacat ttttacgtga gaaggataca
    34681 ttgttttgca attttcctgc tgcaaagaaa gacgctggaa atccaagtgg aagcattttt
    34741 tccttttgga aattttcttt aaaccagcca cgattatctc catgaacggg gatatcaaac
    34801 tccaacatgc ctggaatagc ttcaaccttg cgtgccgcaa gcatcttacc gaaaaaatta
    34861 tctgtcatct atgcttctcc aatcaaacgg agcagatact gtccgtattc atttttctta
    34921 agtggttggg ctaaggtcaa tacatcttca cgactgatat aacccatgcg ataggcaatt
    34981 tcttccaagt ttgctacctg aacattttgc atccgttgga ctgtttcgat gtactgcgaa
    35041 gcctctagta aactttcatg agtgccagta tccaaccaag caaaaccacg tcccataagc
    35101 tcaacggata agtctccacg atccaagtaa gccttgttga catctgtgat ttctaattct
    35161 ccgcgaggac ttggtttgat actcttggca atttcgacaa catcattatc atagaaatag
    35221 agtcctgtca ctgcatagtt tgaacgaggg tattctggct tttcttcgat ggagatagca
    35281 ttcatatttt catcaaattc tacaacacca aagcgttctg gatccttgac atggtagcca
    35341 aagacagtcg cacctttctc tttcttggct gctttttgaa gcattttgct caaaccagga
    35401 ccgtgataga tattgtcccc caagatcaaa gcaacactat catcaccaat aaactcttcc
    35461 ccaatgataa aggcttgtgc caaaccatct ggacttggtt gctctgcata agaaagttta
    35521 ataccaaact cagatccgtc ttgaagaagc tctttaaaac gaggcaaatc ttgaggagtt
    35581 gagattatca aaatatccct aatcccagcc aacatcaatg ttgaaagtgg atagtaaatc
    35641 atgggtttat cataaaccgg cataagttgt tttgatgcag cccgagtcaa aggatataat
    35701 cgtgtccccg aaccacctgc aagaataata cctttcatac tatagtccct cctttttaaa
    35761 tttgttttca taagttatgt tttacttagt ttgagaaaaa cataatagat agcaatttat
    35821 tttttaatct tttattgctt tgattttatt c
//
LOCUS       DAVMJI010000023        34141 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.023, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000023 DAVMJI010000000
VERSION     DAVMJI010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34141
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.023"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..290
                     /locus_tag="VYR58_001317"
     CDS             <1..290
                     /locus_tag="VYR58_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV3622465.1"
                     /translation="QYNGSWYYLNSNGAMVTGWLQNNGSWYYLNANGSMATDWVKDGD
                     TWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
     gene            complement(520..1500)
                     /gene="dusB"
                     /locus_tag="VYR58_001318"
     CDS             complement(520..1500)
                     /gene="dusB"
                     /locus_tag="VYR58_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV3622466.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1487..2359)
                     /gene="hslO"
                     /locus_tag="VYR58_001319"
     CDS             complement(1487..2359)
                     /gene="hslO"
                     /locus_tag="VYR58_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV3622467.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2524..3951
                     /locus_tag="VYR58_001320"
     CDS             2524..3951
                     /locus_tag="VYR58_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV3622468.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLYSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKAWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            4110..5618
                     /gene="glpK"
                     /locus_tag="VYR58_001321"
     CDS             4110..5618
                     /gene="glpK"
                     /locus_tag="VYR58_001321"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV3622469.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5660..7486
                     /gene="glpO"
                     /locus_tag="VYR58_001322"
     CDS             5660..7486
                     /gene="glpO"
                     /locus_tag="VYR58_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV3622470.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKRTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            7554..8258
                     /locus_tag="VYR58_001323"
     CDS             7554..8258
                     /locus_tag="VYR58_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV3622471.1"
                     /translation="MMSELFGEFLGTLILILLGNGVVAGVVLPKTKSNSAGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEVEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8506..8652
                     /locus_tag="VYR58_001324"
     CDS             8506..8652
                     /locus_tag="VYR58_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004247184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622472.1"
                     /translation="MLVEFHKSQGTLETPEVQAEIAQKREEIEQRRAELEGKKQELLN
                     RLNK"
     gene            complement(8739..9347)
                     /locus_tag="VYR58_001325"
     CDS             complement(8739..9347)
                     /locus_tag="VYR58_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622473.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAMIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            10435..11711
                     /gene="ltrA"
                     /locus_tag="VYR58_001326"
                     /pseudo
     CDS             10435..11711
                     /gene="ltrA"
                     /locus_tag="VYR58_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            12167..13345
                     /locus_tag="VYR58_001327"
     CDS             12167..13345
                     /locus_tag="VYR58_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV3622474.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13659..13790
                     /locus_tag="VYR58_001328"
     CDS             13659..13790
                     /locus_tag="VYR58_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV3622475.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13811..15361
                     /gene="dltA"
                     /locus_tag="VYR58_001329"
     CDS             13811..15361
                     /gene="dltA"
                     /locus_tag="VYR58_001329"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV3622476.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPRLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFENLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15358..16602
                     /gene="dltB"
                     /locus_tag="VYR58_001330"
     CDS             15358..16602
                     /gene="dltB"
                     /locus_tag="VYR58_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV3622477.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGIVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16616..16855
                     /gene="dltC"
                     /locus_tag="VYR58_001331"
     CDS             16616..16855
                     /gene="dltC"
                     /locus_tag="VYR58_001331"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV3622478.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16848..18116
                     /gene="dltD"
                     /locus_tag="VYR58_001332"
     CDS             16848..18116
                     /gene="dltD"
                     /locus_tag="VYR58_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV3622479.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            18271..18711
                     /gene="adcR"
                     /locus_tag="VYR58_001333"
     CDS             18271..18711
                     /gene="adcR"
                     /locus_tag="VYR58_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV3622480.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18711..19415
                     /locus_tag="VYR58_001334"
     CDS             18711..19415
                     /locus_tag="VYR58_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV3622481.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19408..20214
                     /locus_tag="VYR58_001335"
     CDS             19408..20214
                     /locus_tag="VYR58_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV3622482.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            20224..21729
                     /gene="adcA"
                     /locus_tag="VYR58_001336"
     CDS             20224..21729
                     /gene="adcA"
                     /locus_tag="VYR58_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV3622483.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQSLDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22858..23631)
                     /locus_tag="VYR58_001337"
     CDS             complement(22858..23631)
                     /locus_tag="VYR58_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV3622484.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPNQKLLDAVELFDGEWVSDIQ"
     gene            23807..25210
                     /locus_tag="VYR58_001338"
     CDS             23807..25210
                     /locus_tag="VYR58_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV3622485.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKEE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            25325..25963
                     /locus_tag="VYR58_001339"
     CDS             25325..25963
                     /locus_tag="VYR58_001339"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV3622486.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            25975..26415
                     /locus_tag="VYR58_001340"
     CDS             25975..26415
                     /locus_tag="VYR58_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV3622487.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26408..26839
                     /locus_tag="VYR58_001341"
     CDS             26408..26839
                     /locus_tag="VYR58_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV3622488.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26830..27300
                     /locus_tag="VYR58_001342"
     CDS             26830..27300
                     /locus_tag="VYR58_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV3622489.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27325..28098
                     /locus_tag="VYR58_001343"
     CDS             27325..28098
                     /locus_tag="VYR58_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV3622490.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            28095..28895
                     /locus_tag="VYR58_001344"
     CDS             28095..28895
                     /locus_tag="VYR58_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV3622491.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            28954..31248
                     /locus_tag="VYR58_001345"
     CDS             28954..31248
                     /locus_tag="VYR58_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV3622492.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            31258..>34141
                     /locus_tag="VYR58_001346"
     CDS             31258..>34141
                     /locus_tag="VYR58_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV3622493.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELE"
BASE COUNT        10523 a         5872 c         7407 g        10339 t
ORIGIN      
        1 tccaatacaa tggttcatgg tactacctaa acagcaatgg tgctatggta acaggatggc
       61 tccaaaacaa tggctcatgg tactacctaa acgctaacgg ttcaatggca acagattggg
      121 tgaaagatgg agatacctgg tactatcttg aagcatcagg tgctatgaaa gcaagccaat
      181 ggttcaaagt atcagataaa tggtactatg tcaatggctc aggtgccctt gcagtcaaca
      241 caactgtaga tagctataga gtcaatgcca atggtgaatg ggtaaactaa acttaatata
      301 actagttaat actgacttcc tgtaagaact ctttaaagta ttccctacaa ataccatatc
      361 ctttcagtag ataatatacc cttgtaggaa gtttagatta aaaaataact ctgtaatctc
      421 tagccggatt tatagcgcta gagactacgg agtttttttg atgaggaaag aatggcggca
      481 ttcaagagac tctttaagag agttacgggt tttaaactat taagccttct ccaattgcaa
      541 gagggcttca atctctgcta gggtgctagc ttgcgaaatg gctccacgga gtttggcagc
      601 gccagatgtt ccacggaggt agtgaggagc gaggccgcgg aattcacgaa ctgcgacgtt
      661 ttctcctttg aggttaatca atcgtttcaa gtgttcgtag gcgatcttca tcttgtcttc
      721 aaaggtcaaa tcaggtagga tttctcctgt ttcaaagtaa tggttgattt ggttgaagag
      781 gtaaggattt cccatggcag ctcggccaat catgactgcg tcagcaccaa cttcttcgat
      841 gcgttgcttg gcttcttgga cagtacggat atcaccgttg gcgatgaatg gaatcttggt
      901 tagagcttgg gcaaccttgt aaagggtctc aaggtctgcg tggccagtat acatttgttc
      961 acgggtacgg ccatgcatgg cgagggcaga aacacctgca gcttcagcag cgagggcatt
     1021 ttctactgcc agagatgggt ccgcccagcc ggtacgcatt ttgacagtaa gtgggatatc
     1081 aaggacagac tggaccttgt tgatgataga gtagatcttg tcaggatcct tgagccacat
     1141 agcaccagct tcgttcttca cgattttgtt gacagggcag cccatgttga tatcgacgat
     1201 atcggtcttg gtgttttctt ggatgaattc tgctgcgcgt gctaggctgt cttcatcgct
     1261 accaaaaagt tggatagaga cagggttttc gccctcatcg atatgaagca tgtgcagggt
     1321 tttttcgttg ttgtattgga ttcccttgtc agagaccatt tccattacaa cgagtccagc
     1381 tccgagctct tttgcgatgg tacgaaaggc tgagttggtc acgccagcca taggcgctaa
     1441 aacggtacga ttgggaatct caacattgcc aatcataaaa ggtgtattaa gatttgtcac
     1501 gaatgagttc ctccaggtcc ttttcatcaa agttgtaagt agtttggcag aattgacaag
     1561 tgatttctgc cccgtggtct tcctctttca tttcctgtaa gtctgagctt ggaaggctgg
     1621 caagagcgtt cataaagcgt tcatggctac agtcacattg gaaacggatt tcttcttcag
     1681 aaagacgctt gtaggcttcg tccccgtaga tagccttgag gagggcttcg atatggtcgt
     1741 cgctttcgag aagagtagag atagctggca tttcttggat gcgtttttca aagcgagcaa
     1801 tctcttcttt cttggctcct ggcaagactt gaactaggaa accacctgca accttgacct
     1861 tgtcttcctc gtccaaaagg acattgaggc cgaccgctga aggcgtttgt tggctttcag
     1921 taaggtaaaa ggcaaggtct tcaccgattt ctccagagat gaggggagtt atagagttgt
     1981 aaggatttcc agtaccgtag tctgtgataa cgaggaattg accatttcca acaaaaggtc
     2041 cgactaggac ttcaccagtc gcagtctttt tgatgtcaac accaggattt tgaacatagc
     2101 ctttgacgtt ccccttggta tcagcgacgg tgataatagc acctagagag ctagagccca
     2161 acaccttaac tgtaagtttg gtatttcctt tttcattggc tgcgagaatc tggctagcga
     2221 taagagttcg accaagcgct acagttgagc tagcttgggt ttgatgtttt tcttgagcag
     2281 tgcggacggt ttcagtgcta tcaaggacaa aagcacgaaa ggctccgctt tctgatatag
     2341 ttttaataat tttatccata gctactattt tagcataaaa atgcccaaag ggggagccgt
     2401 gtgtttactg attttcagga taatggacca ggaaatcagc atgaaaataa aaagagaaac
     2461 agattatttt agcatttgta agatttatgc tatgcttaag gtagaaaatg aaaggggtaa
     2521 caaatgtatt taggagattt gatggagaaa gccgagtgtg gtcaattttc aatcctttcc
     2581 tttctattac aagagtctca gacgaccgtc aaggctgtaa tggaagaaac aggattttca
     2641 aaagcaaccc taaccaaata tgtcaccctg ctcaatgaca aggctttgga tagtggctta
     2701 gaactgacta ttcactcaga agatgaaaat ctgcgtctgt ctatcggtgc agctaccaag
     2761 gggagagata ttcggagctt gtttttgtat agtgctgtta aataccagat tttggtttat
     2821 cttctctacc accaacagtt tttagcccat cagctggctc aagaattggt gattagcgag
     2881 gctacgcttg gtcgtcactt ggctggttta aatcagattt tgtcagaatt tgatttatcc
     2941 atccaaaatg gacgctggag aggtccagag catcagattc gctatttcta tttctgtctt
     3001 ttccgaaagg cctggtcgag tcaggaatgg gaaggtcaca tgcagaaacc agagagaaaa
     3061 caggagattg ccaatttaga ggaaatctgc ggtgcaagtt tgtctgcggg gcagaaattg
     3121 gacttggttc tctgggctca catcagtcaa caacgtcttc gggtcaatgc ttgtcagttt
     3181 caagtcatag aagagaaaat gcgagggtat tttgacaata tcttttatct tcgtttgctg
     3241 agaaaggttc cgtccttttt tgctgggcaa catattccac taggagttga ggatggtgag
     3301 atgatgatat tcttctcttt tctcctatct catcgcattc ttcctcttca tactatggag
     3361 tatattcttg gttttggagg gcagttggca gatttactga cgcaattgat tcaagaaatg
     3421 aagaaggagg aactattggg ggattataca gaggaccatg tcacctatga actcagtcag
     3481 ctttgtgctc aagtctatct ctataagggc tatattttac aggatcgcta caagtaccag
     3541 ttagagaatc gtcatccata tttactgatg gaacatgatt ttaaagagac agcagaggag
     3601 atttttcatg ctctacctac ttttcaacag gggacagatt tagataagaa gattctctgg
     3661 gaatggctcc agttaatcga atatatggct gaaaacggtg gccagcatat gcggattggt
     3721 ctggatttga catctggttt tcttgtcttt tcaaggatgg cagccatttt gaaacggtat
     3781 ttggaataca atcgttttat taccattgaa gcctatgacc ctagtaggca ttatgatttg
     3841 ctggttacca ataaccctat tcataagaag gaacagacac cagtctatta tttaaaaaat
     3901 gacttggata tggaagattt ggcagggatt cgtcagttat tattcactta aaaggcttgg
     3961 ttaatccagg tcttttttgt gaaattcaca caatctcctc acattttttt aaaaattaaa
     4021 aaaagttgat aaacaagaaa gcgctttatt ttgtatacta gtaagtgtaa agaggaaaca
     4081 cctcaagatc tttatcagga ggacagtaca tgtcacaaga aaaatacatc atggctattg
     4141 accagggaac tacaagttct cgtgccatca ttttcaacaa aaaaggggaa aaggttagct
     4201 cgagtcaaaa agagtttacc cagattttcc ctcaggcagg ttgggttgag cacaatgcca
     4261 atgaaatttg gaactctgtt cagtcagtta ttgcgggtgc tttcattgaa agtggtgtca
     4321 agccaaatca aatcgaggca atcgggatta ccaaccaacg tgaaacaacg gttgtctggg
     4381 ataagaaaac aggacttcct atctacaatg ctatcgtttg gcagtcacgc cagacagcac
     4441 ctttggctga gcaactaaaa agccaaggtt atgtggaaaa attccatgaa aagactggtt
     4501 tgattattga tgcttacttc tctgctacca aggttcgttg gattttggat catgtagaag
     4561 gtgctcaaga gcgagcagaa aaaggggaat tgctctttgg tactatcgat acttggttgg
     4621 tttggaaatt gactgacggt gcggctcacg tgactgacta ctcaaatgca gctcgtacca
     4681 tgctttataa cattaaagaa ctcaaatggg atgatgagat tttggaaatc cttaacattc
     4741 cgaaggctat acttccagaa gttcgttcta actccgaaat ctacggcaag acagctccat
     4801 tccatttcta cggtggagag gtgccaatct caggtatggc tggggaccaa caagcagccc
     4861 tctttggaca gttggctttt gagccaggta tggttaagaa tacttatgga acaggctctt
     4921 tcatcatcat gaatactggg gaagagatgc agttgtctga aaacaacctc ttgacaacca
     4981 ttggttacgg aatcaacggt aaggtttatt atgccttgga aggttctatc ttcatcgcag
     5041 gaagtgctat tcagtggctt cgtgacggtc ttcgcatggt tgaaaattca ccagaatctg
     5101 aaaaatacgc tcgtgattct cacaacaacg atgaagttta tgtcgttcca gcctttacag
     5161 gtctaggcgc tccatactgg aaccaaaatg ctcgtggttc cgtctttggt ttgactcgtg
     5221 gaacaagcaa agaagacttt atcaaggcga ctttgcaatc tattgcttat caagtgcgtg
     5281 acatcatcga cactatgcaa gtggatactc agactgccat tcaagtactg aaggtggatg
     5341 gtggtgcagc catgaacaac ttcctcatgc agttccaggc ggatatttta ggcattgaca
     5401 ttgcacgtgc taaaaacttg gaaacaacag ctctaggagc ggccttccta gcaggtttat
     5461 cagtaggata ctggaaagac ttggacgagt tgaaactctt gaacgagaca ggagaactct
     5521 ttgagccatc tatgaacgaa tctcgcaagg aacaactcta caagggctgg aagaaggctg
     5581 tgaaagcaac tcaagtcttt gcggaagtag acgactaata ctggcagaat aaagcgattt
     5641 atttagaaag tgtgtaaata tggaattttc aaaaaaaaca cgtgaattgt caattaaaaa
     5701 aatgcaggaa cgcaccctgg acctcttgat tatcggtgga ggaatcacag gagctggtgt
     5761 agccttgcag gcggcagcta gcggtcttga gactggtttg attgaaatgc aagactttgc
     5821 agaaggaaca tctagtcgtt caacaaaatt ggttcacgga ggacttcgtt acctcaaaca
     5881 atttgacgta gaggtggtct cagatacggt ttctgaacgt gcagtggttc aacaaatcgc
     5941 tccacacatt ccaaaaccag atccaatgct cttaccagtt tacgatgaag atggagcaac
     6001 ctttagcctc ttccgtctta aagtagccat ggacttgtac gaccttttag caggtgtgag
     6061 caacacacca actgcgaaca aggttttgag caaggatcaa gtcttggaac gccagccaaa
     6121 cttgaagaag gaaggcttgg taggaggtgg agtgtatctt gacttccgta acaacgatgc
     6181 gcgtctcgtg attgaaaaca tcaaacgtgc caaccaagac ggtgccctca ttgccaacca
     6241 cgtgaaggca gaaggcttcc tctttgacga aagtggcaag attacaggtg ttgtagctcg
     6301 tgatctcttg acagaccaag tatttgaaat caaggcccgt ctggttatta atacaacagg
     6361 tccttggagt gataaagtac gtaatttgtc taataagaga acgcaattct cacaaatgcg
     6421 cccaactaag ggagttcact tggtagtgga ttcaagcaaa atcaaggttt cacagccagt
     6481 ttactttgac acaggtttgg gtgacggtcg tatggtcttt gttctcccac gtgaaaacaa
     6541 gacttacttt ggtacaactg atacagacta cacaggtgat ttggagcatc caaaagtaac
     6601 tcaagaagat gtagattatc tacttggcat tgtcaacaac cgcttcccag aatccaacat
     6661 caccattgat gatatcgaaa gcagctgggc aggtcttcgt ccattgattg cagggaacag
     6721 tgcctctgac tataatggtg gaaataacgg taccatcagt gatgaaagct ttgacaactt
     6781 gattgcgact gttgaatctt atctctccaa agaaaaaaca cgtgaagatg ttgagtctgc
     6841 tgtcagcaag cttgaaagta gcacatctga gaaatatttg gatccatctg cagtttctcg
     6901 tggatctagc ttggaccgtg atgacaatgg tcttttgact cttgctggtg gtaaaatcac
     6961 agactaccgt aagatggctg aaggagctat ggagcgcgtg gttgacatcc tcaaagcaga
     7021 atttgaccgt agctttaaat tgatcaattc taaaacttac cctgtttcag gtggagaatt
     7081 gaacccagca aatgtggatt cagaaatcga agcctttgcg caacttggag tttcacgtgg
     7141 attggatagc aaggaagctc attacctagc aaatctttat ggttcaaatg caccgaaggt
     7201 ctttgcactt gctcacagct tggaacaagc gccaggtctt agcttagcag acaccttgtc
     7261 tcttcactat gcaatgcgca atgagttgac tcttagccca gttgacttcc ttcttcgtcg
     7321 taccaatcac atgctcttta tgcgtgatag cttggatagt atcgttgagc cagttttgga
     7381 tgaaatggga cgattctatg actggacaga agaagaaaaa gcaacttacc gtgctgatgt
     7441 aaaagcagct cttgctcaaa acgacttagc agaattaaaa aattaagaaa aaataaaaga
     7501 ggtggagggt agcaatcctt gtcgcccgcc ccttttttaa tggagacaga aaaatgatga
     7561 gtgaattatt tggagaattt ttagggactt taatcctgat tcttctagga aatggtgttg
     7621 ttgcaggtgt ggttcttcca aaaaccaaga gcaacagtgc aggttggatt gtgattacta
     7681 tgggttgggg gattgcagtt gcggttgcag tatttgtatc tggcaagctc agtccagctc
     7741 atttaaaccc agctgtgacc atcggtgtgg ccttaaaagg tggtttgcct tgggcttccg
     7801 ttttgcctta tatcttagcc cagttcgcag gggccatgct gggtcagatt ttggtttggt
     7861 tgcaattcaa accgcattat gaggtagaag aaaatgcagg caatatcctg gcaaccttca
     7921 gtactggacc agccatcaag gatactgtat caaacttgat tagcgaaatc cttggaacct
     7981 ttgttttggt gttgacaatc tttgctttgg gtctttacga ttttcaggca ggtatcggaa
     8041 cctttgcagt gggaactttg attgtcggta tcggtctatc actaggtggg acaacaggtt
     8101 atgccttgaa cccagctcgt gaccttggac ctcgtatcat gcacagcatc ttgccaattc
     8161 caaacaaggg agacggagac tggtcttacg cttggattcc tgttgtaggc cctgttatcg
     8221 gagcagcctt ggcagtgctt gtattctcac ttttctaatc tagaaaacaa ttatgttgat
     8281 agagcttggg caagagccca atttcagcaa aaaatgaagt aaatcttctc ataataaaac
     8341 gcatcatatc aagcacgaaa attccacgag gtcaactaca gtcagaaagc tgaacaacaa
     8401 gccaaaacgc ccaaaaaagg cggcaaaaag caagcacctg caagcaacgt gccgaaatag
     8461 tcaaatcctg attatgtcaa cgaattagac ccaaaaatcg ttgatatgct agtagaattt
     8521 cacaagtcac aaggcacttt ggaaactccc gaggtgcaag cagaaatcgc ccaaaaacgt
     8581 gaagaaatcg agcaaaggag agctgagctt gagggtaaaa aacaagagct tttgaaccgc
     8641 ttgaacaaat agagtttcgc aagtattatg cttacaaatt acttgagcaa ttaactaaaa
     8701 tataaaccct acctttatat ctaggcaggg tttatatttt agaaattcac gtaggttgtt
     8761 acggttttta catacccagt atagtttgag tttctatagt attcagtgat aaacttccat
     8821 tttctttgag caacatggat ataagtactt gttatgtagt atggatatgg gctttgtgaa
     8881 tccaagtaag actgataagc ttgtatacca aaatatgctc caccaatcat tgcaccccat
     8941 ggacccccca ataaagcacc tatcctacca atcatataac tgattccagc accagtcatg
     9001 aagttagcga atgtgttagc ttgtttattc ccatgtattg tgttgacgta attccaaaca
     9061 ttaggatcgt atgatctaaa agatatattt aggtcgattt cattcttttg ataagccata
     9121 taaaatgccc cattgatata gacgccgtca gcacgtcgtt caatagtgtc tacacttcca
     9181 tctggattga caacctcaag aacttcatcg cttaaaatat ttacttgcgt atctccgaac
     9241 cgcactgatg agccattctc aaactgagcc tcaccagata caactttaga gtttgccgat
     9301 aagctatcat cagcaaaaac aacaagcgac ggggaaatgc tagacataca gaaaacagac
     9361 ataactagca aacacatgca tttaaacatc ttagacataa cggaaactct tttgtatttt
     9421 tgattttttt caacttttat tatacaataa aaccaaataa aaagaaagcg gtaacaatat
     9481 gcttaatgcg aaaatttttt atatattttt atgtttgatc gttatcgaaa ctacaggctt
     9541 gttgttgttg aaaagaggtc tcgaaatggg ttatttagac acagaagcta ttatcctcgc
     9601 agttttttca tttgcttttt acaacctatg ttcattcgct tgggtctgct ctacaataaa
     9661 aaacaataaa aaataaatag acgtattttc aaaaaaaaaa aaatgcatat ttatattagc
     9721 aaaacgacga tttaaatcgt cgtttttttg tagtacgacg ggcatgtcgt atatctgagg
     9781 tgtaagtcct cggtgggcac ctgctaccgg tgaacccaat agcgattccc aagcctgact
     9841 atcgtgaggt agcagggaga ggaaggatag cgaaatcgtg gctctacgaa caggaacgtg
     9901 atagtaaggc gtatatagcg gataaggagg cttcaaactc taaagtccaa aaaggtagtc
     9961 gtaacctata tgtgtaaatc acgagagtaa ttgaattcgg actaaggttt gtgtgaaaaa
    10021 gataaatctt tctagagtct aaagactctg cgtcagattt cctattttca ctgtaacctt
    10081 ttaacgtcct catatcttgt ataaacgagg aaagatgtac gacttatccc gtgaggtttc
    10141 atgagcgctg aaagcgtagt aacaacgaat catgagaagt cagccgagcc catagtagtg
    10201 aggaaacttc tgtagtggaa gtggagcgaa ggggtgaata ctcaaacagt ctggggagag
    10261 actgtttgag gtctgtcgct agaaagagaa aacgacagat cgaagtaatc ctacttcact
    10321 tgtgtctgta aaatgagtgg tctgatagaa ctggactttg acacgtaatg actagatgaa
    10381 ggttcaccaa tataagatgt ccctcaggca ccaaaacaag aaaggaatac gcacatgtca
    10441 aaactgctag ataagatatt atcacgcgaa aatatgctgg aagcctacaa tcaagtaaaa
    10501 tccaataaag gctcagctgg gattgatgga atgactatcg aagagatgga taattatttc
    10561 agacaaaact ggcgcttgac taaggaactg ataaaacaga gaaaatataa gcctcaacca
    10621 gttcttaaag ttgagatacc taaaccagac ggaggcatcc gtcaactagg aattccaaca
    10681 gttatggata gaatgattca acaggccatt gtctaagtca tgagccccat ttgtgaaccc
    10741 catttctcag atacgagtta tggtttcaga ccaaataggt catgtgaaaa agccatcatg
    10801 aagctcttag aatacttaaa tgacggctat gagtggatag tggatataga cctagagaaa
    10861 tttttcgata cagttcctca agatagattg atgtccttag tacataacat tatcgaagac
    10921 ggagatacgg aatccttgat tcgtaagtat cttcattcag gtgttatcat taatggtcaa
    10981 cgttataaaa cactagttgg tacaccacag ggaggaaatt tatctcctct cttatccaat
    11041 atcatgctta atgaattgga caaggaatta gaaaagaggg gacttcgatt tgtgcgctac
    11101 gcagatgatt gtgtgattac ggtcggaagc gaggagcctc taagcgtgtg atgtattcag
    11161 tcagtcgttt tattgagaaa cggctaggtt tgaaagtaaa catgaccaag actaagatta
    11221 ccagaccaag agagttgaaa tatctaggtt ttgggttctg gaaatcatca gatggttgga
    11281 aaagccgtcc acatcaagat agtgttcgga gatttaagtt taaattgaag aaactaacac
    11341 agaggaaatg gagtatagac ctaacaagac gtattgagca actgaatttg tctattcgag
    11401 gatggataaa ctatttctca ttgggaaata tgaaaagtat agtcgccagc atagatgagc
    11461 gcttgcgtac tcgcctacga gtgattatct ggaagcaatg gaagaagaaa tcgagacgat
    11521 tatggggatt gcttaagtta ggagttccta aatggatagc agataaggta tctggctggg
    11581 gcgaccatta tcaattagta gctcagaagt cggtacttaa acgtgctata tcaaaaccag
    11641 tccttgaaaa acgtggactg gtttcgtgtt tggattatta ccttgaacga catgcgttaa
    11701 aagttagttg aaccgccgta tgccgaacgg cacgtacggt ggtgtgagag gggctagaga
    11761 ttatccccta ctcgattaac tcccctgaaa tttattttaa ttatgcaaat ttcacgtatt
    11821 tttgatgctg agacgacgat cctgggaact tttcagatat ttttttgact atctaaatct
    11881 atcattagaa aagcttagag cgccaaagga tttgagcgtt tttctgattt ttaagacttt
    11941 ttccagtctc tttttcgatt gaagatgtaa ttattctact aactaactaa cttcttagta
    12001 ctagccaaca acgataatca taattcctcc taaaattagg aataataaag gcaatagttt
    12061 ttgttttttc atgtaaaaaa cctcactttt gttttctgct attttatgct aaaatattaa
    12121 aaatcaaatt taattccaaa gtttgtaact aaagggggag cgctacatgt ctaattcatt
    12181 tgtcaagttg ttagtctctc aattatttgc aaatttagca gatattttct ttagagtaac
    12241 aatcattgct aacatataca ttatttcaaa atcagtaatt gccacatcac tagttcctat
    12301 cttaatagga atatcctctt ttgttgcgag tcttttagtt ccgttggtta ctaaaaggtt
    12361 agcgctaaat agggttttat ctttatctca atttggaaag actatattat tggcgatact
    12421 ggtaggaatg tttaccgtaa tgcaatccgt agcgcctttg gtgacctatc tatttgttgt
    12481 tgcaatttcc atactagatg gttttgcagc acccgtttcc tatgctattg tgccacgcta
    12541 tgcgaccgat ttgggtaagg ctaattcagc cttatcaatg actggtgaag ctgttcaatt
    12601 gataggttgg ggattaggtg gactcttgtt tgcaacaatt ggtctgttac ctaccacgtg
    12661 tatcaattta gtcttgtata tcatttctag ctttctgatg ttatttcttc ctaacgctga
    12721 agtggaggtg ttagagtcag aaactaatct tgaaattttg ctcaaaggtt ggaagttagt
    12781 tgctagaaat cctagattaa gactttttgt atcagcaaat ttattggaaa ttttttcaaa
    12841 tacgatttgg gtttcttcca ttatacttgt ttttgtaacg gagttattaa ataaaacgga
    12901 aagttactgg ggatattcta atacagcata ctctattggt attataatta gtggcttaat
    12961 tgcttttagg ctatctgaaa agttccttgc tgctaaatgg gaaagtattc tttttcctct
    13021 tgtagctatg gcaatagtga cactgactat tctatatttt ccaaacgcac agatgttttt
    13081 attattttca gctttagttg gtatgttatc gcaactaaaa gaagttcctg aaagtgtatt
    13141 tcttcaggaa acagtagagg aaaatcattt agttaatgtc tattccgttc ttgaagtgat
    13201 ttctacatta gcattttcag tatttgtttt gctaatgagc tatattactg agagttttgg
    13261 tattagcatc agtttttggc tatcagccat ttgtctgatg atagaagcta ttttaattta
    13321 tatcagacga gattatttta aatgagagag tggttaaaaa gtctttaaaa atcagaaaag
    13381 cgcatagtat caggtgttga aaaaacttga tattgtgtgt tttattatgg gaagatttac
    13441 ttcattgtct cctgaaatgg agttttgaag caggatcact ctatttgaaa atatacatag
    13501 aaaaactgta taatccttaa aataagctga aatctattgg aaacatacgg taaacaattg
    13561 aaaagatact atataaagtg gtacaatggt agaaaaataa gctagtaaga atcactctta
    13621 ttttagcgaa aaattacaga aatgaatggt ttttcttgat gaaacagaga aaagaattgt
    13681 acctctttct tggtcggaca gccttgtatt ttcttatctt tctagggctg ctttacttct
    13741 ttagctatct tggtcagggt caaggaagct ttatctataa tgaattttaa cttgaaggag
    13801 aatccctatt gtgtcaaata aaccaatagc agatatgatt gaaaccattg agcattttgc
    13861 tcagacacag cctagctatc ctgtctataa tgttttgggg caggaacaca cttatggcga
    13921 tttaaaggct gattcggata gtttggctgc agtcattgac caactaggct tgcctgagaa
    13981 gtctcctgtg gttgtttttg gtggccaaga atatgaaatg ttggcaacct ttgtagcgct
    14041 gactaagtca ggtcatgcct acattccaat tgatagccat tcggccttgg agcgagtttc
    14101 agctatttta gaagtagcag agccaagatt gattattgcc atttcagcct ttcccttgga
    14161 gcaggtttct acaccaatga taaatctagc tcaggttcaa gaagcctttg cccaagggaa
    14221 caactatgaa atcacgcatc cagtcaaggg agatgataat tactacatta tctttacttc
    14281 tggtacgact ggtaagccta agggagtgca gatttcacat gataatctcc tcagctttac
    14341 aaactggatg attacggata aggaatttgc gacaccgagt cgtccgcaaa tgctggcaca
    14401 gccaccttat tcttttgact tgtctgtcat gtattgggca ccgaccttgg cacttggtgg
    14461 tacgcttttc actcttcctt cagtcatcac tcaggacttt aagcaactct ttgcggctat
    14521 cttttcattg ccaatcgcta tctggacatc aacaccatcc tttgcagata tggccatgtt
    14581 gtctgaatac ttcaacagtg agaaaatgcc tggaatcacg catttctact ttgatggtga
    14641 agaattgacg gtcaaaacag ctcaaaaact gcgcgagcgt ttcccaaatg cccgtatcat
    14701 caatgcttac ggcccaacag aagcgacagt agctctgtca gcagttgccg tgacagacga
    14761 gatgttagcg actctcaaac gcctaccaat cggctatacc aaggctgatt ctccaacctt
    14821 tatcattgac gaggaaggaa ataaactgcc aaatggtgag cagggagaaa tcattgtttc
    14881 tgggccagct gtttcaaaag gttatatgaa caatcctgaa aaaacagcag aagccttctt
    14941 tgagtttgaa aatctgccag cctatcacac aggcgatgtg ggaaccatga cagatgaggg
    15001 cttgcttctc tacggcggac gcatggactt ccagattaag tttaacggtt accgcattga
    15061 gttagaagat gtctctcaaa acctcaacaa gtctcgcttt atcgaatctg ctgtcgcagt
    15121 accgcgctat aacaaggacc acaaggtaca aaatctattg gcttatgtca tcttaaaaga
    15181 cggtgttcgt gagcagtttg agcgagatat cgatattacc aaggccatca aggaagacct
    15241 gacagacatc atgatgtcct acatgatgcc atctaaattc ctttaccgag acagtttgcc
    15301 actgactcca aatggaaaga ttgacatcaa aggattgatt aacgaggtga ataagagatg
    15361 atggagtttt ttcaacagct tcctcattta gagccatatg gcaatcctca gtattttgtt
    15421 tatgtgattg ctgcaacctt gcccatcttt ataggtctct ttttcaagaa acgctttgcc
    15481 tggtatgaag tgttggtaag tctcttcttt attgtcacca tgttggtggg tggaaagacc
    15541 aatcaactag ctgccttggg tatttacctt tgctgggaaa tattgctcct gcttttctac
    15601 aagcattatc gaaaaagcaa ggatggcaag tgggtcttct acttagttag ttttctgtcc
    15661 ctacttccga ttatctttgt caaggtgcaa ccagctatca atggaacgca gtctttgctt
    15721 gggttcttgg gaatttctta ccttaccttt cgttcggttg gaattgtcat cgagctgaga
    15781 gatggagtga ttaaggattt taccctctgg gaattcctcc gtttccttct cttcatgcca
    15841 actttctcga gtggtccaat cgatcgcttt aagcgattta atgaaaatta tcaggctatt
    15901 cctgagcgag atgagttgat ggatatgctg gatgaatctg tccgctatat catgtggggc
    15961 tttttgtata agtttatcct agctcatgtt ttaggagaga ccttactacc tcctctgaag
    16021 aatttagcct tgcagtcagg tggcttcttt aatctctatg ccttggcagt tatgtatact
    16081 tttggtctgg agctcttctt tgactttgca ggttattcta tgtttgcttt ggccatctca
    16141 aacttgatgg gaatccgtag ccctatcaac tttaacaagc cctttttatc aagggattta
    16201 aaggagtttt ggaatcgctg gcatatgagt ctgtccttct ggttccgtga ctttgtcttt
    16261 atgcgaatgg tgatggtgtt aaccagaaag aaagtcttta aaaatcgtaa tgtaacctca
    16321 agcatggcct acattgtaaa tatgctgatt atgggatttt ggcatggcgt gacctggtac
    16381 tatatcgcct atggactctt tcatggacta ggcttggtca tcaatgatgc ctgggttcgc
    16441 aagaaaaaaa cgctcaataa ggaacggaaa aaagcaggga aggctgccct acctgagaat
    16501 cgctggattc agttgcttgg tatagttgtc actttccatg ttgtcatgtt gtcattctta
    16561 atcttttctg gattcttgaa taatctatgg tttaaaaaat aaaaggaaat aaaatatgga
    16621 tatcaaatca gaagttattg aaattattga tgagttgttt atggaagatg tttctgacat
    16681 gatggatgaa gatctttttg atgcaggtgt cttggatagt atgggaacgg ttgagttgat
    16741 tgtggagatt gagaaccgtt ttgacattcg tgtccctgta acagagtttg gtcgtgacga
    16801 ctggaataca gctaataaaa tcatagctgg tattgtggag ctacaaaatg cttaaacgct
    16861 tatggatgat cttcggaccg gtcttgatag ctggtttgtt ggtttttctg ctcattttct
    16921 tttatcctac tgagatgcat cataatctag gagctgaaaa gcgttcagca gtggctacta
    16981 ctatcgatag ttttaaggag cgaagtcaaa aagtcagagc actatctgat ccaaatgtgc
    17041 gttttgttcc cttctttggc tctagtgaat ggcttcgttt tgacggtgct catcctgcgg
    17101 tattagctga gaaatacaat cgttcctacc gtccttatct tttaggacag gggggagctg
    17161 catcgcttaa ccaatatttt ggaatgcaac agatgttacc acagctggag aataaacaag
    17221 ttgtgtatgt tatctcacct cagtggttca gtaaaaatgg ctatgatcca gcagccttcc
    17281 agcagtattt taatggagac cagttgacta gttttctgaa acatcaatct ggggatcagg
    17341 ctagtcaata tgcagcgact cgcttactgc aacagttccc aaacgtagct atgaaggacc
    17401 tggttcagaa gttggcaagt aaagaagaat tgtcgacagc agacaatgaa atgattgaat
    17461 tattggctcg ttttaatgaa cgccaagcct ccttttttgg tcagttttcg gttagaggct
    17521 atgttaacta cgataagcat gtagctaagt atttaaaaat cttgccagac cagttttctt
    17581 atcaagcaat agaagatgtt gtcaaagcag atgctgaaaa aaatacttcc aataatgaga
    17641 tgggaatgga aaattatttc tataatgagc agatcaagaa ggatttgaag aaattaaagg
    17701 attctcagaa aagctttacc tatctcaagt cgccagagta taatgacttg cagttggttt
    17761 taacacagtt ttctaaatct aaggtaaacc cgatttttat cattccacct gttaataaaa
    17821 aatggatgga ctatgctggt ctacgagagg atatgtacca acaaacggtg cagaagattc
    17881 gctaccagtt agaaagtcaa ggttttacca atatagcaga tttttctaag gacggcgggg
    17941 agcctttctt tatgaaggac accattcacc ttggttggtt gggttggttg gcttttgaca
    18001 aggcagttga tcctttccta tccaatccca caccagctcc gacttaccat ctgaatgagc
    18061 gctttttcag caaagattgg gcgacttatg atggagatgt caaagaattt caatagataa
    18121 tataatatag aagagttcaa gaatgaaact agttttcacg ttttttcttg actctttttt
    18181 tgcttgtgat ataattaact ggtaaacaaa atgtcaaaga atagtatttt tctcttaaaa
    18241 aagagaagtc taaaaggaaa ggagtcagat atgagacagc tagcaaagga tatcaatgct
    18301 tttttgaatg aggtgatttt gcaggcggaa aatcagcatg aaatcctaat aggtcattgc
    18361 actagcgagg tggccctgac caatactcag gagcatatcc ttatgctctt gtcagaggaa
    18421 tctttaacaa attcagaatt ggcccgtcgt ctcaatgtca gtcaggcggc agttaccaag
    18481 gccattaagt ctttggtcaa ggaagggatg ttggaaacat ctaaagattc taaagatgcg
    18541 cgtgtgattt tttatcagtt gactgacttg gctcgtccaa tcgctgagga gcaccaccat
    18601 caccatgagc atacactttt aacctatgaa caagtggcga ctcagtttac tccaaatgaa
    18661 caaaaagtga ttcagcggtt tttgactgct ttagtaggag aaatcaaata atgagatata
    18721 ttacggtaga ggatttgtcc ttctattatg ataaggagcc tgttcttgaa catatcaatt
    18781 atagtgttga tagtggggaa tttgttacct tgactgggga aaatggagcg gctaagacga
    18841 cgctcatcaa ggccagtctt ggaattctgc aaccacgcat tggaaaggtg gctatttcaa
    18901 agacaaatac gcaaggtaag aaattgagaa tagcctatct tcctcaacaa attgccagtt
    18961 ttaatgctgg ttttccaagt acggtctatg aatttgtcaa gtcgggtcgc tatccgagaa
    19021 aaggctggtt ccgtcgtttg aatgctcatg atgaggagca tatcaaggct agtctggact
    19081 cagttggcat gtgggaacat cgagacaaac gcttggggtc tctatctggg ggacaaaagc
    19141 agcgagcggt gattgcgcgt atgtttgctt ctgaccctga tgtgtttatc ctagacgagc
    19201 cgacaacggg gatggatgca ggaagtaaaa atgaatttta cgaactcatg caccacagcg
    19261 cccatcatca tggcaaggct gttttgatga ttacccatga ccctgaagaa gttaaggatt
    19321 atgcggatcg caatattcat ctagtccgta accaagactc gccatggcgt tgtttcaatg
    19381 ttcatgagaa tggccaggag gtgggccatg cttagtttat tatcttacga ctttatacaa
    19441 cgcgcctttt tggcggttat tgctatgagt cttttctcac cggtattggg aaccttcctc
    19501 atcttgcgtc gtcagagttt gatgagtgat acccttagcc acgtctcact ttcaggtgta
    19561 gcctttggtc tggttttggg gatttctcca actgtttcta ctattgccat tgtcttgatt
    19621 gcggcggtct ttctggagta tctccgtacg gtttacaaga gctttatgga aatcgggaca
    19681 gctatcctca tgtcaacagg tctggctgtt tctctgattg tcatgagcaa gggtaaaagc
    19741 tcgagttcaa tgagtttgga ccaatatctc tttggttcga tcgtgactat cagtgaagaa
    19801 caggtcattt ccctctttgt cattgcggcg gttgttttga ttttgacctt tctctttctt
    19861 cgtcctatgt atatcttaac ttttgacgaa gatacggcct ttgtggatgg cttgccagtt
    19921 cgtaccatgt ccattctttt taacatggtg acaggggtgg ctattgccct tatgattcct
    19981 gcagcaggag ctcttctggt atcgaccatt atggtcttgc cagctagtat tgccctgcgt
    20041 ctggggaaaa actttaaatc ggttatgctg cttgccagtg cgattggctt tttgggaatg
    20101 gtagcaggac tttacatttc ctactatgca gaaacacctg caagtgcaag tattaccatt
    20161 atttttgtaa ctgtctttat actaatcagt ttagtaagac gttttatcaa ataggagacg
    20221 aacgtgaaaa aaattagctt attactagcc agtctatgtg ccttgttttt agtggcttgt
    20281 tccaatcaaa aacaggcaga tggtaaactc aatatcgtga caacctttta ccctgtctat
    20341 gaatttacca agcaagtcgc aggagatacg gctaatgtag aactcctaat cggtgctggg
    20401 acagaacctc atgaatacga accatctgcc aaggcagttg ccaaaatcca agatgcagat
    20461 accttcgttt atgaaaatga aaacatggaa acatgggtac ctaaattgct agataccttg
    20521 gataagaaaa aagtgaaaac catcaaggcg acaggcgata tgttgctctt gccaggtggc
    20581 gaggaagaag agggagacca tgaccatgga gaagaaggtc atcaccatga gtttgacccc
    20641 catgtttggt tatcaccagt tcgtgccatt aaactagtag agcacatccg cgacagcttg
    20701 tcagcagatt atcctgataa aaaagagacc tttgagaaga atgcagctgc ctatatcgaa
    20761 aaattgcaat ccttggataa ggcttacgca gaaggcttgt ctcaagcaaa acaaaagagc
    20821 tttgtgactc aacacgcagc ctttaactat cttgccttgg actatggact caaacaagtc
    20881 gcaatctcag gcctttctcc agatgcagag ccatcagctg ctcgcttggc agaattgaca
    20941 gagtatgtca agaaaaataa aatcgcctat atctattttg aagaaaatgc ctcacaagcc
    21001 cttgctaaca cactttcaaa agaagcaggt gtcaaaactg atgtcctcaa tcctttagaa
    21061 agtctgacag aagaggacac caaggctgga gaaaattaca tctctatcat ggagaaaaac
    21121 ctcaaggctt tgaaacaaac aacagaccaa gaaggcccag caatcgagcc tgaaaaggca
    21181 gaggatacca agacagtcca aaatggttac ttcgaggatg cagctgtcaa ggaccgcacc
    21241 ttgagtgact atgcaggtaa ctggcaatca gtttatcctt tccttgaaga cggcacgttt
    21301 gaccaagtct ttgactacaa ggctaagttg actggtaaga tgacccaggc tgagtacaag
    21361 gcttactata caaaaggcta tcagacagat gtgactaaga ttaacattac tgataatact
    21421 atggaatttg ttcaaggtgg acaaagcaag aaatatactt acaagtatgt cggtaagaaa
    21481 attttgactt acaagaaagg caatcgtggc gtgcgtttcc tctttgaagc cacagatgct
    21541 gacgctggac aattcaagta tgttcagttt agtgaccaca atgttgcccc agttaaggca
    21601 gaacatttcc atatcttttt tggaggtaca agccaagaag ctctatttga agaaatggat
    21661 aattggccaa cctactaccc agataaccta tctggccaag aaatcgctca agaaatgttg
    21721 gcgcattaat gagaaatcga ctagttcata agagctagtc ggtttttggg tactagatgg
    21781 ctaacttcat tatagacttt tcagaactaa ggaactttaa aaaaataaat aaaactcttg
    21841 aaatatctgg acttatatgc tagaatgtag ttagtgtata aggttcatta gaacaccaaa
    21901 gcccctaact agtgccatag ttaagggctt ttttgacgta tcttagcgat ttaacgggtg
    21961 tttataggct agtcagtcgg tctacttctt accatctagc catttgcaga cgaaatacaa
    22021 gataattcca gctataacat ctgctataat agtaagagca agctctggta taaggctcat
    22081 tagtttcacc tcctctcacg aaccgtaagg aaggtaatcg gtaaccgatg acaaaagtat
    22141 tataccacac taaatttaga tcatcaacct cacttaatgc ttgaactatt gtagattata
    22201 tgctagaatg tagttaattg ataaggttca ttagaacacc aaagccccta actatggccg
    22261 tagttaaggg cttttttgac gtatcttagc gatttaacgg gtgtttatag gctagtcact
    22321 cggtctactc cttactatct agccatctgc agacgaaata caagataatt ccagctataa
    22381 catccgctat aatagtaaga gcgagctcta tgataaggct cattagtttc acctcctctc
    22441 acgaacccat aggaacgtaa tcggtaaccg atgacaaaaa tagtatacca caatacattt
    22501 agatcatcaa ggtcacttaa ttcttgaaat atagggtcta ggcgacaaag tctttaaaat
    22561 cagaaaaacg cataatatca ggtgtgcaaa aacttgatac tatgcgtttt attgtgggaa
    22621 ggtttactcc attttctcct gaaattgagt ttttgtccag cctctgtttt tagaattgct
    22681 aagaaaataa tgtcatgtgg tgaatatttg taaatcagtc agcagacaga acgaatactc
    22741 ttcgaaaatc tcttcacatc atgtcagctt cgtcttgccg tgtccatggg ggacttgact
    22801 tcatcagttt tcaaatctgt actttgagca agctgagact agcttcctat ttgattttca
    22861 ttgaatatca gaaacccatt ctccatcaaa taattcgact gcgtctaata atttttgatt
    22921 tggcaaggtg tcagaaataa aggttgtgta tttggagagg ggattaattt taaaaaatcc
    22981 agtcttgtaa aatttagaac tatcaatcag taagatggtt tcatgggctt tgtcaataat
    23041 attctttttt gaaatagctt ggctgagaga agcttcataa acatattggt catcaatacc
    23101 tcttgctgaa caaaatgcta aatcgatatt aaaatgatct aataaagaat tttccttatc
    23161 atagttgacc acggaacagg attgatgttt gacctcgcca gatgtgataa agattttgga
    23221 gctatcttta acagtttcag atagggtttg tgcagtatgt aaaccatttg taaaaataat
    23281 caaattatca agttcagaaa gatagggaca aagttcgtag acagtcgtac tggaatccag
    23341 atagatacac atgcctgacc gaataaagtc tttagcgaga ctagcgatta gtcttttttg
    23401 cctagtactt tctccttccc gtatttgatg agaaagttca attgtgttca tagaggacag
    23461 ggtcacgtat ccgtgctttc ttttgataag accttgattt tctaagaaaa ttaaatcacg
    23521 acgtaaggta cttgtgctgg agaaagtgat ttctgccagc tcttttacgg caattctttt
    23581 tttctttttg atgatttcaa tcaattcaag tacacgttca tcttttatca taagctcctc
    23641 ctaatttatc atttcaacta tattatagca caaattggag gaatttgaat tatttttatg
    23701 aatattgggt taacatttga acattattca agtaagcgtt cacatattga aaaaataaaa
    23761 tgtggggatt ataataaact taatcaagga cgaagagaga agaaaaatgg aagcggtttt
    23821 agcaatagat ttaggtgcga cttctggaag agcaatcgtt ggttaccttt ctgaaaataa
    23881 actagtaatg gaagaaataa atcgcttttc taatctacct attagagtaa aagggcattt
    23941 atcttgggat attgactttc tactagctaa aattcttgaa agtatccgct tggctaatac
    24001 tagttacaag attttatcta tcggtattga cacatgggga gttgattttg gactgattga
    24061 taatgaaggt aagctgttat tacaacctgt tcattatcgt gatgaaagaa caaagggagt
    24121 gttaaaggaa atatctgaaa tgactgaatt agaaaaactg tattcagaga caggaaatca
    24181 gattatggag ataaatacct tgtttcaact ctttaaggca cgtcaagaat ctcctgactc
    24241 tttctataag accaataaga ttcttttaat gccagatttg tttaattatc tcttgacagg
    24301 taagtttgct acagaaaaaa gcattgcttc aacaactcaa ttatttgatc ctaggagtca
    24361 aaattggaat cagaatatct taaaactatt tgaattggat tcatctttac ttcctgaaat
    24421 tgtttcagag ggaaatgttc ttggaaggat aaaagaggag tatggtttag gcgatattcc
    24481 tgttgtgaat gtttgtagtc atgatacagc aagtgcgatt gtctcagtac ctaagacaga
    24541 aggtagttta tttatttcat caggtacttg gtctttggtt ggagtggaac ttacttcacc
    24601 gattcttact accgaatcct tcagttatgg atttacaaat gaagtcggta aagatggaga
    24661 gattacattt ctgaagaatt gtacagggtt gtggatcata gaggaactaa gacgttcatt
    24721 tgaacgaaga gggaaagcct attcttttga tgatattagg acaatggtgg agaaagaaaa
    24781 agaaaatctt cctctgattg atactgaatc aactgaattt gcaacagaat ctgatatgca
    24841 caagactttg acagaatatc tagcttatca tcatgaaact agagagtgga cagatggaca
    24901 actatttaag attgtttatg aaagcctagc tgaaacgtat aggaaagcga tagagttact
    24961 agaagaacta actcataagg tttataagag gatatatgtg attggaggag gtgctagagc
    25021 cagttacttt aaccaaatga ttgctgatag aactggtaaa gaggttctta caggttcgac
    25081 tgagggtaca gctgtgggga atattgttgt gcagctcata gctatgggac aattaaaagg
    25141 gatggaagaa gctcaccatg ttattgagga gttcctacaa ttagagagtt attactccca
    25201 aaagaattaa aaagattgag agtttgtaaa tttgcctccc tcccccttct taagttttgt
    25261 acaagaaggg gggataattg gtgaattgaa aaatatttag tgttttgata tgaggaggac
    25321 aagaatgtca gatgtaaaac aagaattaat taagtatggc aagaagctag tagaaacaga
    25381 tttgacgaaa ggaacaggtg ggaatctcag tgttttcgat cgtgaaaaac aattgatggc
    25441 aattaccccg tcgggtattg atttctttga aatcaaagaa tccgatattg tagtgatgga
    25501 tattaatgga aatgttgtag agggagaacg cttgccatct agcgaatggt atatgcattt
    25561 gattcaatat caaactcgtg atgatatcga tgcaattatc catgctcata caacttatgc
    25621 aacagtatta gcttgtctca gagaaccact tccggctagt cattatatga ttgcagtggc
    25681 agggaaagat gttcgggtag ctgagtatgc aacatatggt acgaaagaat tggctgtgaa
    25741 tgcagctaaa gcaatggaag gtcgtagagc agttttacta gcgaatcatg gaattttagc
    25801 aggtgcacaa aatttattga atgcatttaa tattgttgaa gaagttgaat attgtgcaaa
    25861 aatttattgt ttagctaaga attttggaga gccagtagtt cttcctgatg aggagatgga
    25921 tttaatggca gaaaaattta aaacatacgg tcagagaaaa tagggaggat attaatgtta
    25981 aaacatatac cgaaaaatat ttctccagat ttattgaaga ctttaatgga aatgggacat
    26041 ggagatgaaa tagtattagc tgacgcgaat tatccttctg cctcatgtgc aaataagcta
    26101 attcgttgtg atggtgtaaa tattccagaa ttattagatt ccattctgta tttaatgcca
    26161 ttagatagtt acgtcgatag ttcaattcag tttatgaacg ttgtttcggg tgatgatatt
    26221 cctaagatat ggggtaccta tagacagatg attgaaggtc atggtacaga tcttaaaacg
    26281 attacttatc ttagaagaga agacttttat gaacgtagta agaaagctta tgctattgtt
    26341 gctacaggag aaacttcact ttatgctaat attatcctta agaaaggagt agttgttgaa
    26401 agagaaaatg tttaatagag gaattttagt tgccagtcat ggtaattttg ctagcggagc
    26461 tctcatgacc gcagaaatgt ttgttggtga gacaacaaat gatagagtta ggacattagg
    26521 tttgatgcct ggagagaata ttgtagagtt tgaacattat tttaaaaatc aagtaaatga
    26581 actgttagac tcaaatcaag aggttatcgt tttgactgac ttgattggag gaagtcctaa
    26641 taatgtggct ttgtcacggt ttttaaattt ggattcagtt gatattgtaa cagggtttaa
    26701 tatccctctc ctagtggaat taatatcaag ttatgattca aaaatcaatt tagaagaaat
    26761 tgttcaaaat gctcaaaata gtttgtttaa tgttaaacaa caacttaacg tagaggagga
    26821 agaggattta tgtctataga gtttgttcgt attgatgacc gtctggtaca tggtcaagtt
    26881 gtcactacgt ggctaaaaaa gtatgatatt gagcaagtta tcattgttaa tgatcgcatc
    26941 tcagaagata aaacacgaca atctatttta aagatttctg caccggtagg tttaaaaatt
    27001 gttttcttta gtgtaaaacg gtttgtggaa gttttaaact ctgtgccaat aaaaaagaga
    27061 acaatgctga tatatacaaa tccaaaagat gtgtatgatt ctattgaagg aaatttaaaa
    27121 ttggagtacc tcaatgtagg acagatgagt aaaacggagg aaaatgaaaa ggtaacggga
    27181 ggtgtagctc taggtgaaga agacaaatat tattttaaga aaatagttga taagggaacg
    27241 agagttgaaa ttcaaatggt tcctaatgat aaagttacaa tgttggaaaa atttttataa
    27301 aaataattta aggaggtaca gtatatgcta ttcacacaag cattactggt gacattagtt
    27361 gggattattg ccactattga ctataatgga ccgttattta tgattcaccg tccgttagtt
    27421 acaagtgcaa tggttggctt agtcttagga gatttcaccc aaggtgttct tattggttca
    27481 gctcttgaat taacttggct cggtgtaaca ggtattggag gttacactcc accagatact
    27541 atttcaggtg cgattattgg tactgcattt ggtattttgt ctggtcaagg agaaactgct
    27601 ggtatcgcta tagcagttcc aattgcagtt gctacccaac agttggatgt tcttgcaaaa
    27661 actttagatg tttattttgt gaaaaaagct gataatgatg ctaaaaacgg agattattca
    27721 aagatcggtt tttatcatta ttcaagtttg gttttaatca ctttatttaa aattgtacca
    27781 attttcctag ctattatgct tggaggggaa tatgtggcag acttgtttgc taaggttcca
    27841 ccaatcgtta tgcagggact taactctgca ggtgctttac taccttcaat tggttttggt
    27901 atgcttttaa atatgatgct caagaaaaat atgtgggtat tcttgttgat tggattcatt
    27961 tgttctgtgt atggaggaat gtcaaccatt gggatctcac tagttggtat tgcggtagca
    28021 tacttctacg atatgattgg aagtaaacca caagaaacaa cttcaagtag tgatgttgag
    28081 gaggatcttg atctatgatg aataataaag taactaaagt tgaacttaaa aaagttttca
    28141 aacgaagttt tatgtatggt tcttcatgga actatgagag aatgcagaac ctaggttttc
    28201 tatatacaat tcttccagta ttgaaaaaac tatacccaga caaagattca gcttctcctg
    28261 caatgaaacg tcaccttgag tttttcaata ctcatcaaac agcggcacca tttattcttg
    28321 gagttacttc cgctatggaa gaacaagaag gaaatgaagg tgcagcttca attactggta
    28381 ttaaagttgg cttgatgggg ccgctggctg gtctaggaga tagtttgttc tggctgacac
    28441 tagttcctat ctgttttagt attggtgcgt cttattctaa agacggcggt gctttaggta
    28501 tctttatcgc cttaatattg tttaatatta ttaatattcc tgttaaatat ttcggtttga
    28561 aatatgggta tactaagggt tctagtctta tccaagaaaa taatacaaaa ggaacattga
    28621 atcgcgttac gagtatggcg acagcattag ggctagtact agtgggtggt ttgattccat
    28681 caatggttgg tattaatttt ggattagaat ttaagcaggg ggaacttgtt atttctgttc
    28741 aagaaatgat tacaaaatta attccaggat ttatccctat ggctttgact ttattaatgt
    28801 gtaaattaat tagaaaagga aagaatccgg ttgtactaat ctttagtgtt atggctattg
    28861 gagttatcct agttgtttta ggaattttga agtagtagaa agtgtggagg tggtatttgg
    28921 gatatcacct ccattttgga agagaggtaa agagtgaaat tatggtataa gaaagctgcc
    28981 tcaaattgga atgaagcctt gccgattggg aacggtcatt taggtggtat gatttatggt
    29041 tcagctacaa aagaatgtat tcaactaaac gatgagacta tttggtatag aggaaagtca
    29101 gatagaaata atccagactc actattgcat cttaaaaaaa ttcgggaata tcttttagat
    29161 ggagaaattc agaaagccga agaattgata aagttaacaa tgtttgctac cccaagagat
    29221 caaagccact atgaattact tggggaactt tacattgagc atatagatat tcagtcttgt
    29281 gctctttcat tgtatgaaag agagctagat ttagatacag ctatttctaa tgttgtgttt
    29341 gagcctaata gttgtaattt acaaataaaa agagaatatt ttacgagttt taataagaat
    29401 attttatgtt gccgtatagt gtcatcagtt caaaacacat taaatttaaa cattaatttg
    29461 ggtagaaata aacggtttaa tgatgaagta tctaaactgg attcaagtac aattttaatg
    29521 tcggcctctg ctggaggtag aaaaggtgtt cagtttaaag tggtatgtca ttctaaggtt
    29581 acggatggtg aagtaagtgt attgggagag acaatagtta ttcggaatgc tacagaggta
    29641 tttctttatc tcaaatcaat gacggattat tggggaaata tagatatttc ttctcttcag
    29701 ggagaattta gtagtattga ttactttaca gaaaaagatg aacatgtaaa aaaatatcag
    29761 gagcaattta atagagttga ttttaaacta gactatagta aagattgtct tagcattcca
    29821 acgaatctac ttcttgaaaa cactaaaaag tatagtaact acttgactaa cttgttattt
    29881 cattatggaa gatatctgtt aatatcgtct agtcaaccga atggtttacc tgccaatctt
    29941 caaggaatat ggtgtgatga attaaatcca atttggggtt ctaaatatac gattaatatt
    30001 aatactcaaa tgaattattg gatggtaggt ccatgtgatt taccagaagt agaatatcca
    30061 ttatttgata tgctcgaaag aatgagagaa ccgggaagac taaccgctaa gaaaatgtat
    30121 ggagctagag gttttacagc acatcataat acggatggtt ttggcgatac ggctccccaa
    30181 tctcatgcca tgggggctgc aatttgggta ttaactattc catggttatg tactcatatt
    30241 tgggaacact atttatattt ccaagatgag cgtattctta cggaacattt tgaaatgata
    30301 aaagaagcat ttcttttctt tgaagattat ttatttgagg tggatggcta cttgatgaca
    30361 ggtccaagtg tctcaccgga aaataaatat cgcttaaaaa atggtattga aggaaatgct
    30421 tgtctatcat ctacaattga taatcaaatt ttaagatatt tttgtgattc atgcattgga
    30481 attgcaaaac aattaggaga caattcggat tttattagtc gtgtgaagga gttaaaaaag
    30541 aaattaccta gaacaaaaat aggtagtaat gggcaaatac aagaatggct agaggattat
    30601 gaagaagtag agcctggtca tagacacatt tcacctctat ttgggcttta tccttataat
    30661 gagattgata ttcataaaac tccggaatta gcagaagcag ctaaaatcac tatcaatagg
    30721 agattatcaa acgctaactt tttatcttca caggataggg agcaagcgat taataattgg
    30781 ttagtaagtg gtttgcatgc tagtacacaa acaggttgga gtgctgcatg gctgattcat
    30841 ttttttgcga gactatatca aggtgaacct gcttataacc agattaatgg tttgttaaat
    30901 aatgcgactc ttggcaattt atttcttgac catccaccat ttcaaattga tggtaattta
    30961 ggtttggtga gtggaatttg tgaattatta gtacagagcc atcataattg gttatcacta
    31021 attccagctt taccttctgc ttggtcagaa ggagaagtga aaggtttcag agtaagagga
    31081 ggatataagg tatcgtttgc ttggaaaaat ggggatataa cattcctaaa attggaagga
    31141 ggaaacaaag atcaaaaagt aagagtaaga atatatggca aaaatactga tgtacaaaat
    31201 attgaattgg tatttaattc agaaaaaatt attgagttaa atttttaggt ataagtcatg
    31261 aataaagaaa aaataaaaag aaaattaatc acaatactgt ttgtatgtat tgggatgtta
    31321 tgttttggat tgttagcagg agttaaggct gataatcgtg ttcaaatgag aacgacgatt
    31381 aataatgaat cgccattgtt gctttctccg ttgtatggca atgataatgg taacggatta
    31441 tggtggggga acacattgaa gggagcatgg gaagctattc ctgaagatgt aaagccatat
    31501 gcagcgattg aacttcatcc tgcaaaagtc tgtaaaccaa caagttgtat tccacgagat
    31561 acgaaagaat tgagagaatg gtatgtcaag atgttggagg aagctcaaag tctaaacatt
    31621 ccagttttct tggttattat gtcggctgga gagcgtaata cagttcctcc agagtggtta
    31681 gatgaacaat tccaaaagta tagtgtgtta aaaggtgttt taaatattga gaattattgg
    31741 atttacaata accagttagc tccgcatagt gctaaatatt tggaagtttg tgccaaatat
    31801 ggagcgcatt ttatctggca tgatcatgaa aaatggttct gggaaactat tatgaatgat
    31861 ccgacattct ttgaagcgag tcaaaaatat cataaaaatt tggtgttggc aactaaaaat
    31921 acgccaataa gagatgatgc gggtacagat tctatcgtta gtggattttg gttgagtggc
    31981 ttatgtgata actggggctc atcaacagat acatggaaat ggtgggaaaa acattataca
    32041 aacacatttg aaactggaag agctagggat atgagatcct atgcatcgga accagaatca
    32101 atgattgcta tggaaatgat gaatgtatat actgggggag gcacagttta taattttgaa
    32161 tgtgccgcgt atacatttat gacaaatgat gtaccaactc cagcatttac taaaggtatt
    32221 attcctttct ttagacatgc tatacaaaat ccagctccaa gtaaggaaga agttgtaaat
    32281 agaacaaaag ctgtattttg gaatggagaa ggtaggatta gttcattaaa cggattttat
    32341 caaggacttt attcgaatga tgaaacaatg cctttatata ataatgggag atatcatatt
    32401 cttcctgtaa tacatgagaa aattgataag gaaaagattt catctatatt ccctaatgca
    32461 aaaattttga ctaaaaatag tgaggaattg tctagtaaag tcaactattt aaactcgctt
    32521 tatccaaaac tttatgaagg agatgggtat gctcagcgtg taggtaattc ctggtatatt
    32581 tataatagta atgctaatat caataaaaat cagcaagtaa tgttgcctat gtatactaat
    32641 aatacaaagt cgttatcgtt agatttgacg ccacatactt acgctgttgt taaagaaaat
    32701 ccaaataatt tacatatttt attgaacaat tacaggacag ataagacagc tatgtgggca
    32761 ttatcaggaa attttgatgc atcaaaaagt tggaagaaag aagaattaga gttagcgaac
    32821 tggataagca aaaattattc catcaatcct gtagataatg actttaggac aacaacactt
    32881 acattaaaag ggcatactgg tcataaacct cagataaata taagtggcga taaaaatcat
    32941 tatacttata cagaaaattg ggatgagaat acccatgttt ataccattac ggttaatcat
    33001 aatggaatgg tagagatgtc tataaatact gaagggacag gcccagtccc tttcccaaca
    33061 ccagataaat ttaatgatgg taatttgaat atagcatatg caaaaccaac aacacaaagt
    33121 tctgtagatt acaatggaga ccctaataga gctgtggatg gtaacagaaa tggtaatttt
    33181 aactctggtt cggtaacaca cactagggca gataatccct cttggtggga agtcgatttg
    33241 aaaaaaatgg ataaagttgg gcttgttaaa atttataatc gcacagatgc tgagactcaa
    33301 cgtctatcta attttgatgt gattctatat gacaataata gaaacgaagt tgctaagaaa
    33361 catgttaata atttgtcggg tgaatctgtt agtctagatt tcaaagaaaa aggagcaagg
    33421 tatattaaag ttaaattact aacgagtgga gtgcctttga gtttagcaga agtagaggtt
    33481 tttagagaat cagatggtaa gcaatctgaa gaggatatag ataaaataac agaagataaa
    33541 gtagtctcta caaataaggt agctactcaa agttcaacca attatgaggg tgtagctgct
    33601 ttagcagttg atggtaataa agatggagat tacggacatc attcggtgac tcatactaag
    33661 gcagattcta acgcttggtg gcaggtcgat ctgggagaag agtttacggt ttctaaagtt
    33721 gatatttata atagaacaga tgccgaacct cagcgtttat ctaattttga tgttattttt
    33781 ctatcttcat caggagaaga agtttttaga agacattttg ataaagtagt tgatggtttg
    33841 ttatctttaa aagtaccttc tgtaggggct aagctagtca aaatagaatt aaaatcagca
    33901 gctattccgt taagtttagc ggaagttgaa gtctatggtt caaagagaac tccgaagaaa
    33961 ctttctaata ttgcattaac caaagaaact cgacagagtt caacggatta caatggtttt
    34021 tctcgtctag cagttgatgg aaataaaaac ggagattatg gtcatcattc agtgactcat
    34081 accaaaggag attctccttc atggtgggag atagatttag cacaaaccga agaattagaa
    34141 a
//
LOCUS       DAVMJI010000024        33546 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.024, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000024 DAVMJI010000000
VERSION     DAVMJI010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33546
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.024"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(177..527)
                     /locus_tag="VYR58_001347"
     CDS             complement(177..527)
                     /locus_tag="VYR58_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622494.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LRKSKGVHKGRCRN"
     gene            complement(667..1002)
                     /locus_tag="VYR58_001348"
     CDS             complement(667..1002)
                     /locus_tag="VYR58_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622495.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(1093..2403)
                     /gene="der"
                     /locus_tag="VYR58_001349"
     CDS             complement(1093..2403)
                     /gene="der"
                     /locus_tag="VYR58_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV3622496.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(2417..3130)
                     /locus_tag="VYR58_001350"
     CDS             complement(2417..3130)
                     /locus_tag="VYR58_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV3622497.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(3127..4023)
                     /gene="dnaI"
                     /locus_tag="VYR58_001351"
     CDS             complement(3127..4023)
                     /gene="dnaI"
                     /locus_tag="VYR58_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV3622498.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(4024..5193)
                     /locus_tag="VYR58_001352"
     CDS             complement(4024..5193)
                     /locus_tag="VYR58_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV3622499.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQII
                     STKRMREKIAQKPVSSDFSLKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(5194..5667)
                     /gene="nrdR"
                     /locus_tag="VYR58_001353"
     CDS             complement(5194..5667)
                     /gene="nrdR"
                     /locus_tag="VYR58_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV3622500.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            5807..6172
                     /locus_tag="VYR58_001354"
     CDS             5807..6172
                     /locus_tag="VYR58_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV3622501.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            6177..6872
                     /locus_tag="VYR58_001355"
     CDS             6177..6872
                     /locus_tag="VYR58_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622502.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            6889..7656
                     /locus_tag="VYR58_001356"
     CDS             6889..7656
                     /locus_tag="VYR58_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622503.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(8068..9267)
                     /locus_tag="VYR58_001357"
     CDS             complement(8068..9267)
                     /locus_tag="VYR58_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622504.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(9264..10157)
                     /locus_tag="VYR58_001358"
     CDS             complement(9264..10157)
                     /locus_tag="VYR58_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622505.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQDQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            10273..10353
                     /locus_tag="VYR58_001359"
                     /pseudo
     CDS             10273..10353
                     /locus_tag="VYR58_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            10838..11051
                     /locus_tag="VYR58_001360"
                     /pseudo
     CDS             10838..11051
                     /locus_tag="VYR58_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11466..12083
                     /locus_tag="VYR58_001361"
     CDS             11466..12083
                     /locus_tag="VYR58_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV3622506.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(12403..13290)
                     /locus_tag="VYR58_001362"
     CDS             complement(12403..13290)
                     /locus_tag="VYR58_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV3622507.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVVRHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(13439..15322)
                     /locus_tag="VYR58_001363"
     CDS             complement(13439..15322)
                     /locus_tag="VYR58_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV3622508.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     SQGNKVKAGDVLGKFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            15699..17153
                     /locus_tag="VYR58_001364"
     CDS             15699..17153
                     /locus_tag="VYR58_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV3622509.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGIYYELDYGHKTN"
     gene            17134..18099
                     /locus_tag="VYR58_001365"
     CDS             17134..18099
                     /locus_tag="VYR58_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV3622510.1"
                     /translation="MVTKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(18134..19408)
                     /locus_tag="VYR58_001366"
     CDS             complement(18134..19408)
                     /locus_tag="VYR58_001366"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV3622511.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQIANPKLAQEKIASKKAELLELANQAYPSIVKRGGGASDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(19408..20580)
                     /locus_tag="VYR58_001367"
     CDS             complement(19408..20580)
                     /locus_tag="VYR58_001367"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV3622512.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(20711..20959)
                     /locus_tag="VYR58_001368"
     CDS             complement(20711..20959)
                     /locus_tag="VYR58_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622513.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(21027..21650)
                     /locus_tag="VYR58_001369"
                     /pseudo
     CDS             complement(21027..21650)
                     /locus_tag="VYR58_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21712..22161)
                     /locus_tag="VYR58_001370"
     CDS             complement(21712..22161)
                     /locus_tag="VYR58_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV3622514.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(22163..22921)
                     /locus_tag="VYR58_001371"
     CDS             complement(22163..22921)
                     /locus_tag="VYR58_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV3622515.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAKPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(23036..25015)
                     /gene="pknB"
                     /locus_tag="VYR58_001372"
     CDS             complement(23036..25015)
                     /gene="pknB"
                     /locus_tag="VYR58_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV3622516.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(25012..25752)
                     /locus_tag="VYR58_001373"
     CDS             complement(25012..25752)
                     /locus_tag="VYR58_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV3622517.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(25767..27080)
                     /gene="rsmB"
                     /locus_tag="VYR58_001374"
     CDS             complement(25767..27080)
                     /gene="rsmB"
                     /locus_tag="VYR58_001374"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV3622518.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(27073..28008)
                     /locus_tag="VYR58_001375"
     CDS             complement(27073..28008)
                     /locus_tag="VYR58_001375"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV3622519.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHAFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(28021..30417)
                     /locus_tag="VYR58_001376"
     CDS             complement(28021..30417)
                     /locus_tag="VYR58_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV3622520.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(30483..30797)
                     /locus_tag="VYR58_001377"
     CDS             complement(30483..30797)
                     /locus_tag="VYR58_001377"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV3622521.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(30822..31448)
                     /gene="gmk"
                     /locus_tag="VYR58_001378"
     CDS             complement(30822..31448)
                     /gene="gmk"
                     /locus_tag="VYR58_001378"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV3622522.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(31578..33191)
                     /locus_tag="VYR58_001379"
     CDS             complement(31578..33191)
                     /locus_tag="VYR58_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV3622523.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
BASE COUNT         9483 a         7615 c         6455 g         9993 t
ORIGIN      
        1 tgtgaacgaa tcaattaggg gatctaaagc attttatacc aatgttttat aagttgtatt
       61 gtattattcc atattcaatc cactatacaa gatgaatatt tctctcaagt ttcataatca
      121 aaataaaaat gactgtatct atagctccat aaacaaatca tagatacagt cattttttag
      181 ttcctacacc ttcctttatg cacaccttta gatttcctta gttcccgtct caagtcaagc
      241 atttttttga aacagatata gtctaaccag tcactagcaa aagcgataag tagtaataat
      301 agccaaatac cccataactt gatatctgtc aaatttctca agacgatatt gaaaaacaga
      361 actgaaaaaa ctgtccaagc aaggctaaaa agagcataga gggtgatgta aatccagtaa
      421 aaatagtaaa aaattgggaa aaatttactt tctctattat ccttgtcaat ccagctgaaa
      481 aagtaaaaac agggtaataa gattatcatt ttaaacaagt gttccatcac aagcctcctt
      541 ttttaaattg ttttctttag tttcgttcta ttaaatgtta ttaccaatat aaaccttgga
      601 atagcgtgta ataaatgatt ttagaggtac cataagccac ctcctacaaa tagaaaccga
      661 tataaatcaa tgccttccac ccttagactt ccctagttcc tgtctcaagc gaaacatttc
      721 tttgaaacag gaataagtta accaattcat accaatagct agcagaataa aaagaaacca
      781 aatgccccat aacttgatat ctgtcacatt tctcaagacg gtattgaaaa acagaactga
      841 aacaactgtc caagcaaggc taaaaagaga atagaagggg atgtaaaacc agtaaaaata
      901 ataaaaaatt ggaaaaaact tactatttct gttggccttc tcaatccagt tatcaaaata
      961 aaagtacggt gctaaaagta agaatttaaa caaatgttcc atcaccgaca tcaccctcct
     1021 tcttttgata gcgttttcta ttattttatt atatcaaaaa aatccggaac tgtcattcca
     1081 gattctactt ttttatttgc gttttcttgc gatgagatga atcggtgttc cctcaaaaac
     1141 aaaggccttg cggatttgat tttccaagaa acgcaggtaa gaaaagtgca tgagttcttc
     1201 ttcattgaca aagatgacaa aggttggtgg tttggttgcc acttgggtcg catagaaaat
     1261 cttgagacgt tttcctttgt ctgtcggtgt tgggttgatg gcaatggcat ccatgatgac
     1321 atcgttcaag acagctgatg gaatacgtgt attttgactt tcgctgattt gcttaatcat
     1381 ctcaggaagt ttgtggagac gttgcttggt taaagctgat acaaagataa tcggtgcgta
     1441 aggcaggtat tggaactgct cacggatatc ttcttcccag tttttcatag tgtggttatc
     1501 tttttcaagc gtatcccact tgttgaccac gataatcatc cctttaccag cttcatgggc
     1561 aaatcctgcg atacgcttgt cgtactcacg aatgccttct tccgcattga tgaccatcaa
     1621 gaccacatct gaacggtcaa tagcacgcat ggcacgcata acagagtatt tctcagtatt
     1681 ttcataaacc ttaccagact tacgcatacc agccgtatca atcatggtaa actcttgacc
     1741 atctgtatct gtaaagtggg tatcaatggc atcacgagtt gttccagcaa caggactagc
     1801 aataacacgg tcttcgccca agatagcatt gatcaagctt gattttccaa cgtttggacg
     1861 accaatcagg ctaaacttaa tgacatctgg attttcttct tcatattcat ttggaaggtt
     1921 ttccacaatc gcatctagta catcccctgt accgatacca tggacagatg agataggcag
     1981 tggttcaccc aaaccgaggg catagaaatc atagatatca tttcgcatct cagggttgtc
     2041 caccttgtta actgcgagga taactggttt gtgggtctta taaagcttac gggctacgta
     2101 ttcgtctgca tcggtaattc cttccttacc ggacacgaca aagacgataa catctgcttc
     2161 ttccatggca atttctgcct ggtgcttgat ttgttccatg aaaggagcat cgacatcatc
     2221 aattcctcct gtatcaatca tgctaaaaga acgattgagc cactcacccg ttgcataaat
     2281 acggtcacgt gtcactcctt cgacatcttc tacaatggag attcgctcac cagcgatccg
     2341 attaaatagg gttgatttcc caacattggg acgtcctaca atggcaatag ttggtagggc
     2401 cataatttct cactttctac aataatttct tctgttcaag attttttcta gttgagcttg
     2461 gttcagcttg accaaactgt tctgctaggc gctgactcca gcttgtggtc gcacgcgccc
     2521 cagcatagtc agcctgaaca cggtcataag cttggattgc ctcagttgac tgttcttggt
     2581 attcttcctc aaagacaaca ttctctagtg gcagtctcgg tttcatatca tgatgttgat
     2641 ttggcacacc cagtgccatc ccaaagacag aataggtgta gtcaggtagg ttaaagagct
     2701 ctgccacttc ttcagacttg tatcgaacca aaccgataat cacaccacca tagcccaagc
     2761 tttcagctgc caacaaggcg ttttgtccag caagagctgc atcgaccgaa ctaatcaaga
     2821 gaccttccac accttggggt tggaaggtgt cggtatgaag tcgggctccc ttttctgctc
     2881 ggttcaaatc tccgacaaag agaaggaaaa cagcagactg gcgaatggct tcttgaggta
     2941 ccaattcata caaggcatct ttcttctctt gacttcgtac cacaatcaca gagtaggatt
     3001 ggaaattctt ccaagatgat gccatctggg ctgctgtcaa aatctcattt aagtctactt
     3061 ggggaatttc ttgctcttta aacctgcgca ctgaagtatg agccttcatc aatttaatgg
     3121 tttctgtcat cgacggttta ctccttctaa acgagtctcc tcagccaaat aacggatgcg
     3181 ttccatgacc cgtctggctt cccaggtttc gtcatttcca tgtttcactt tcgcaaaatg
     3241 cttctccaaa tcttcaaagt tgaagttgga tgtgaaaaag gtcggtaaat tttcctgcat
     3301 ccgatattgg agaatgacct gcaggatttc gtcacgcacc caagcggtgg attgctcggc
     3361 accaatatca tctaaaatca ggacttcaga aagcttaatc tcatccacta aggtcttaac
     3421 attgccatca ccgatagcat ttttgacatc aatgacaaag ctaggatagt ggaggagagt
     3481 tgatgaaaca ccacgttttt ctgataaatc atgagctaag gccgccacca tgaaactttt
     3541 acccacacca aagtctccat ataagtaaag accttttcga atagctggat attgctccac
     3601 gaaggctagt agcttttcaa aaactggtaa gcgccccaaa tcatccaagt caacttgagc
     3661 caaactagct ttcttgagac tggctggtag attgattaac ttgagacggt tcttaatagc
     3721 cgcttctttt tcagccgcga ttagctcagg agtttcttca tatgaaacat ctgcatagcc
     3781 atgattctta accaaaatcg gcttgtagcc tttggcaata taatccgtat ccccacggag
     3841 aaacttgtca cgctcggtga tgtactgatt aaacttggag atactgcgat ttaattcctc
     3901 tggagtcaag gattcttgct ggataaaagc cgcaacatca gggtccttca tgattttctg
     3961 gaccaaatct tgataataaa aacggctggg ttgacgtttg agtacgtctc cgacactttc
     4021 catctaatct cctccttttt ctaatcgagc taatagttct tgcttcttac gttctagttc
     4081 cagacgagtt tcctcgctgg tttcattctt atattcagga ttactccatt taggaacatt
     4141 ggtttttact ggggcagtct gattctgttt ttgtgttttt gctttctgtc ctcgctcacg
     4201 gatgcgcaag actgcctttt ctgccgaatg aatcttttga taggcatagt cattggctac
     4261 cttcatggca tatttctcat tgatatttgc cgaatcgacc ttattaaagg tcaataaaag
     4321 aatgatattg atgacttcgt ccagcaagcc caagccagcc atctgttgca agagttctct
     4381 ttctgtttgg gtaatggttc ccttgcgtgt ttgcttgatt tctgccaaga actgcagggc
     4441 agttttactt ttggcttctt tgataatggt cgcttcctta agactaaagt cagaggaaac
     4501 tggtttttga gcaatttttt cacgcatgcg tttggttgaa ataatctgag aaacagctgt
     4561 tgacttggcc aattgatagg tttcaaacca agtccatttc ttctcctcgg caatagcaaa
     4621 gaggtttaag acatcggact gctcatccgc aaagcgaagt ccatctcgag ccataagctg
     4681 acgaaaatgg tccaagtcaa aatcgttggc cactttcttc ttgagaccaa ggtcttcttg
     4741 actgcctagt tctgccaatt ctggaaagac ttgattgagt gagacaggta tttcttcacc
     4801 atcagcactt tcaactttca aatcctccac agctacatcg ccaatctttt tctctaagag
     4861 tctgcgataa acaggatgcc ccaagaagtc ttgactagat agaggagcat ggagggctag
     4921 ctgataaaca tccccctttt gatagagagt caagagatta aaagcagata agattttcaa
     4981 tgattttatc agtctatcca tcccaaagtt gagatgattg aggatacttg aaaaaagata
     5041 ttcctttcta ccattatccc aaaaactaat cgtataaaga taaaggctca gtgcctcctg
     5101 accgataatc gggaggtagc actgtaccag agatgaggta tcttgcgaca cccgattatt
     5161 ctttagataa gaaaaacggt caattggctt catttatctt tcctttttct ttttagagga
     5221 ctgggtgatt tgttggagca agctctctaa ctcactgaca tccttaaaac tacgatagac
     5281 actagcaaaa cgtacatagg taatctcgtc caattcagcc aactcctcca tgacgagtga
     5341 accaatgtcc tcactttgaa tttcattttc atttcgacca cggagtttct gttcgatacg
     5401 attgactacc atgttgattt catcacttga cacaggacgt ttctgggctg agcggataat
     5461 cccattaaag attttatctc tggagaattg ttcccgtgtg ccatcttttt taacaaccac
     5521 taaggttctt tcttctactc gttcgtaggt tgtaaaacgg tgttggcatt cgtcgcactc
     5581 acgtcttcta cgaatggtgt tcccttcttc tgcttggcga ctatcgataa cacttgactt
     5641 ggtagcccca cattttggac aacgcatcct ttccctcctt atcgttttct tttcattata
     5701 ccatttttta agcgattccc aaaacaattc ttctttttgc ttgacaagtt ttttgttttg
     5761 ttgtattatt tagttaagac aaaaggataa gagaaaggag actaagatgt cctggacatt
     5821 tgacaacaaa aaacccatct atttacagat tatggagaaa atcaagcttc agattgtttc
     5881 ccatacactg gaacccaatc aacaacttcc aaccgtgagg gagctagcta gcgaggctgg
     5941 tgtcaatccc aataccatcc aaagagcctt atcagacctt gaacgagaag gatttgtcta
     6001 cagcaagcga acaactggac gatttgtgac taaggataag gagctaatcg ctcagtcacg
     6061 caaacaatta tcagaagaag aattggaaca cttcgtttcc tccatgatcc attttggcta
     6121 tgaaaaagaa gaactaccag gcgtagtcag tgattatatt aaaggagttt aagcctatgt
     6181 cattactagt atttgaaaat gtatccaaat catatggagc aacaccagcc cttgaaaatg
     6241 tttctcttga cattccagct ggaaaaattg tcggccttct tgggccaaac ggctcaggaa
     6301 aaacaaccct gattaaacta attaatggcc tcttacaacc agatcaagga cgtgtcctca
     6361 tcaacgacat ggacccaagc ccagcaacca aggccgttgt agcttatttg cctgatacga
     6421 cctatctcaa tgagcaaatg aaggtcaaag aagccctaac ctacttcaag accttctata
     6481 aagatttcaa tcttgaacgc gctcatcatc tacttgcaga cctgggcatt gatgaaaata
     6541 gtcgtctcaa gaaactatca aaaggaaaca aagaaaaggt tcaactgatt ttggttatga
     6601 gccgtgatgc tcgtctctat gttttggatg aacccattgg tggggtggat ccagcagccc
     6661 gtgcttatat cctcaatacc attatcaaca actactcacc aacttctacc gttttgattt
     6721 ctacccactt gatttctgat atcgagccaa tcttggatga aattgtcttc ctaaaagacg
     6781 gaaaagtcgt ccgtcaagga aatgtagatg atattcgcta cgagtcaggt gaatccattg
     6841 accaactctt ccgtcaggaa tttaaggcct aagcaaagga gattatttat gttttggaat
     6901 ttagttcact acgaatttaa aaatgttaac aagtggtatt tagccctcta cgcagccgtg
     6961 ctagtccttt ctgccctcat cggaatacag acacaaggct ttaaaaatct accttaccaa
     7021 gaaagtcagg ctactatgct actttttcta gctacagtct ttggtggctt gatgcttaca
     7081 cttgcgattt caaccatttt cttgattatt aaacgcttca aaggtagtgt ctacgaccga
     7141 caaggctatc tgactttgac cttgccagtt tctgaacacc atatcatcac agccaaacta
     7201 atcggtgcct ttatctggtc attgattagc accgctgtat tggctctaag tgctgttatt
     7261 attctggctt taacagctcc agaatggatt cctctttctt atgtgattac atttgtagaa
     7321 acacatctcc ctcagatctt tcttacaggt atatccttcc tactaaatac catttcagga
     7381 atcctctgca tctacctggc tatttccatt ggacagcttt tcaatgaata ccgtacagca
     7441 ctcgctgttg cagcctacat tggtatccaa atcgtcattg gatttattga acttttcttc
     7501 aatcttagtt ctaatttcta tgtcaattca ctggtaggac tcaatgacca tttctatatg
     7561 ggagcaggta tagccattgt taaagaactc atattcatag ctatctttta tctcggaacc
     7621 tactacatct tgagaaataa ggttaatttg ctttaaataa tttttaccta gatatgtaac
     7681 atactcatag aacaaaagag accaggcaaa aagtctttaa aattagaaaa cgcatagtat
     7741 caagtgttga atatgaactg cccccaaaag ttagacagaa aaaatctaac ttttgggggg
     7801 cagttcaaaa aatccttgat attatgcgtt ttttgtgagc tgacttattt cctttcacta
     7861 tatcgcaaaa tgaaataaga acggaacgat gggattttgg aattcaaatc aatttataag
     7921 aatgttttag aagtaatatt atcctattcc agattcagtt cactatacaa ttgagttttc
     7981 aagcaacctg tttacataat gtgtacataa ttaggttcgt gattccaccc ttttcacctt
     8041 taaaaacctc gctttcgcaa ggctcttcta tttataagat aaggcacgtt taaaggtttt
     8101 ccaaatccct aaatcatccg tttgaagaac gagactagca tacatgcgtc cgataaatcc
     8161 tgttgctacc accgcaaaaa tcactgtaat agcaagtgaa atccatgctt ctgctccccc
     8221 cgcatagcca ttaatcgttc gaaacggcat aaagaaggtc gaaataaagg gaatataaga
     8281 accaatcttc aagaggagat tgtcaccagc tgcacctaga gctgtcactc caaaaaaacc
     8341 acccataatc aaaatcatca aaggcgacaa ggctttccct gagtcctcag gacgagaaac
     8401 catagatcct aggaaggctg ccaagactac atacatgaaa agactgatca aaataaagag
     8461 caaggtattc agtgagatag catctcccaa gtgatccaaa ataccagact gagccaagaa
     8521 tggcaaatct ttaaagagca aaacggcagc cagaccacct acaacataga tcccaatatg
     8581 cgttaaaatc actagaaaca gagccatcat ccgcgcatag aaatagtgac ttgcccttat
     8641 gctagaaaaa acgacttcca taattttggt gcctttttca ctggcaactt cctgagccgt
     8701 tacacccgca taggtaatca gaatcatata aagaaagaat cctaaggcac ctgctgcaat
     8761 tgtttgaata aactttttat tttccttggc ttcatcaatc ttttctgtga attgaattgt
     8821 ctgcgctaag cgtttttcct gctcttgaga caaggaagca gttgaacgat taagctgatt
     8881 ttgcagttca ttgagtgtac ctgtaacctc aaatttaatt ccattttcaa gcgatgtttc
     8941 gccatgataa actgccttta gaacactatc ttcttgatca atggtcaaat aaccttttaa
     9001 tttttcttct ttaattgctt ctttggcact tgcttcatct ttatagtcga agttaacacc
     9061 atttacattc ttcagtcctt ctgctacaga tggcactgtt gtcactactg ccactttatt
     9121 atttttagcc atagaagaac cttggagatg cccaattcct acagagattc ctaaaaagag
     9181 gaacggcgaa atcaccataa agaagaaact ccatgactcg acatgtcgaa gataggtttc
     9241 cttgattaca acccacatat ttctcatact tccactcctg attctagttt aaagatttca
     9301 tcgatagttg gcgcttgttg gtcaaatgtt gcgatatatt gatcttgagt caagattggg
     9361 aagagttccc ttccagcgct ctcatcctcc aaaatcaatt tccaactgcc ttgtttggtc
     9421 aagctcacct gtttgacatg aggaagattt tccaattctt ccttgcttcg ttcacttgaa
     9481 acaaagagac gcgttttccc gtattgattg cggacatcct gaactggtcc gtgcaagacc
     9541 acacggccat ctcggatcat cagaatatcg tcacaaagtt cctcaacatt ggtcatgaca
     9601 tggtcagaaa agataatggt tgctccgcgc tctttttcct gaaaaatgac ttgtttgagc
     9661 aattctgtat taactgggtc caatccacta aaaggctcat ccaagataat caggtctggt
     9721 tcatgaatca gagtaataat gagctgaatc ttctgctgat ttccttttga cagactcttg
     9781 attttatctg tcagctttcc tttcacttcc aacctcttca tccattgagg gagtttttct
     9841 ttgacttctt tggcatccat gccttttaga gtcgccaagt agcgaacttg ttcaagaact
     9901 gtcaatttag gcatgagact gcgttcttca ggcagataac caatccgagc ataggtctcc
     9961 tgacgaatat cctgaccatc cagaccgatt tctccctgat attctaggaa ttttaaaata
    10021 ctatggaaaa tcgttgtttt tccagcacca ttttttccga ctagtcccaa aatacgacct
    10081 ggtcgcgctt gaaagtcaat accaaacaaa acttgcttgg atccaaaact tttctctaga
    10141 cttcttactt ctagcatctt tcacctccga aatttcttgc actcattata ctcctttttg
    10201 atagccttta caatgttttt gtccattttt agaagactat tgctgtgtaa aatatggcct
    10261 ggagcacttt tatactcaat gaaaagcaaa gagcaaacta ggaagctagc cgtaggctgc
    10321 tcaaagtaca gctttgaggt tgcagataaa actgacgaag tcagctcaaa acactgtttt
    10381 gaggttgtgg atagaactga cgaagtcagt aactatatct acggcaaggc gaagctgacg
    10441 tggtttgaag agattttcga agagtattag tgataaatcc attatacagt agcaaactta
    10501 atttatacct tccgctcctc aactgtctat ttttaatcct gaattgttat ttgagtaact
    10561 cctttttcct cataaagttt tcttcctcta aaacttctgg aaaaaagcga atagtttcag
    10621 acaacatttt tataagaaac aagttcatct gtcatttcaa gaaggagtaa tcctttatct
    10681 actaatggac ggaacggaat tcaaccgctt gtccgatatg ttttctaagg attatatagt
    10741 aaaatgaaat aaaaacagga caaatagatc gggacagtca aatcgatttc taacaatgtt
    10801 ttagaagtag atgcgtacta ttctagtttc aatctattat atctattatg cacaccacta
    10861 taggatctaa taaaaatcac aacaagttca ttcatagatg gttacctcag ggaactaaga
    10921 aaacgactac aaaggaagtc gcattcatcg aaaagtggat taacaactat cctaaaaaat
    10981 gcttgaacta caagtccccc agagaagact tctggatgac taacttgaac ttgaaattta
    11041 gcaataatta attcaccatc taactatatt tagtaattat ttcagaactg attaatatta
    11101 aaattaacta acaattcaaa ggattcatac tagccataaa ttacgtccat cagagagaga
    11161 ttcttactac ttttagattt tagtctttct agcttcagaa tacatctaaa ctttagggaa
    11221 aatgactatt cgaaagcgcg aatgcctcaa aattatctca gataagctat tcgaaactta
    11281 gaatgctttt aaatttatgg aattgcgatt attcgaaacc tagaatgcat ataaccttta
    11341 gttgacagac ctattctaag tctcgaaggg ctatttactt tctattcctt atcaaaaaag
    11401 actcattccc cctttctcct ccaaaatatg gtatagtaga aatatactat ctatgaggag
    11461 tttacatgtc acaggataaa caaatgaaag ctgtttctcc ccttctgcag cgagttatca
    11521 atatctcatc gattgtcggt ggggttggga gtttgatttt ctgtatttgg gcttatcagg
    11581 ctgggatttt acaatccaag gaaaccctct ctgcctttat ccagcaggca ggcatctggg
    11641 gtccacctct ctttatcttt ttacagattt tacagactgt cgtccctatc attccagggg
    11701 ccttgacctc ggtggctggg gtctttatct acgggcacat catcgggact atctacaact
    11761 atatcggcat cgtgattggc tgtgccatta tcttttatct agtgcgccta tacggagctg
    11821 cctttgtcca gtctgtcgtc agcaagcgca cctacgacaa gtacatcggc tggctagata
    11881 agggcaatcg ttttgaccgc ttctttattt ttatgatgat ttggcccatt agcccagctg
    11941 actttctctg tatgctggct gccctgacca agatgagttt caagcgctac atgaccatca
    12001 tcattctgac caaacccttt accctcgtgg tttataccta cggtctgacc tatattattg
    12061 actttttctg gcaaatgctt tgacacgtaa aaaatccgtt tggtttccca agtggatttt
    12121 taaagcgtag attaactata gcttgatact aaatatactt tggtatggaa atcatgcata
    12181 tttttcgata gtgaggcgag gacttaccta gccttcccgc cgtgatagaa acacctgaaa
    12241 tctaatggtt tcaggtattc ggaaactttg agcctagtgt ctcaaagttt aggtatggaa
    12301 tttcgaagaa agtcgctacc gtccgtaatc acttaaggaa aggctcaaaa atattgtttt
    12361 caaccacaaa atccgtttgg tttcccaagc ggattttgtg ctttattttg aaacttcttt
    12421 tgcaagaaca aagttcccaa gtgtggcaga accatttcct gcgactgctg gcgtcacgat
    12481 atagtcacgc acatctggta ctggtaggta accattaaga agagatgtaa atttctcacg
    12541 gacacggtcc agcatatgtt gttgagccat gacccctcca ccaaagacaa tcacgtctgg
    12601 gcggaaagtc actgtcgcat taaccgcagc ttgagcgata tagtaggctt gaacatccca
    12661 aacagggttg ttgagttcaa tattttcccc acgtacacct gtacgagctt ccaaacttgg
    12721 accagctgca tagccttcca gacatccctt atggaaagga caaacaccct taaactcttt
    12781 ttcaatatcc attgggtgtc taacaacata ataatgaccc atttcagggt gacccacacc
    12841 accgataaac tcaccacgtt ggatgacacc tgcaccgata cctgtaccga ttgtgtagta
    12901 aaccaagttt tcgatacgac caccagcatt gttacgggca accacttcac cgtaagcaga
    12961 gctgtttacg tctgttgtga agtacattgg cacgtttagg gcgcgacgaa gggcaccaag
    13021 caagtccaca tttgcccagt ttggttttgg agtcgtcgtg ataaagccat aagtttttga
    13081 gtttttgtca atatcaatcg gcccaaatga accaactgca agaccagcaa ggttatcgaa
    13141 ttttgagaag aactcaatgg ttttatcgat tgtttcgatt ggagttgttg ttggaaattg
    13201 tgttttttct acaacgttaa agttttcatc accgacggca cagacaaact ttgtaccgcc
    13261 cgcttccaag cttccatata attttgtcat gataaacctc ttgtttttat tttctttatt
    13321 atagcatact tcgaaagtct aaatgtctct attttttaga ttttcctctg taaatcttac
    13381 tatctaataa aaacgaacaa acatgtcatt tgttcgtttt cacattagag aggattgatt
    13441 agattttcac ttcgatcaca gcatccccct tcgaaactga acctgttgcg actggagcta
    13501 ctgaagcgta gtcacctgta tttgtaacga taaccattgt tgtatcatca agtccagctg
    13561 cagcgatttt gtttgagtca aattttccca gaacatcgcc agctttcacc ttattacctt
    13621 gagaaacttt tgcttcaaaa ccgtcaccgt tcatagatac agtgtcaata ccaacgtgaa
    13681 tcaaaacttc agcaccattt cttgttttca aaccaaaagc gtgccctgtt ggaaaggcaa
    13741 ttgaaacttc agcatcagct ggtgcataga ccacgccttg gcttggtttc acagcgatac
    13801 cttgtcccat agctccactt gagaagactg ggtcattgac atcagcaaga gcgacaacat
    13861 caccgacgat aggagttaca agtgtttcat tttgaagagc tgctggcgca acttcttctt
    13921 tttcttcagc cacttcagct tgttttgcag ctgcagttgc gtctacttca tcttcgtaac
    13981 caaacatgta agtaagagca aaaccaaggg caaatgatac agctaccata agaaggtatt
    14041 gtggaagttg tccgttaccc acataaagca ttgtaccagg gatgatggtg ataccattac
    14101 cagtaccagc aagtccaagg atagaagcca atccaccacc gattgcacca gcaatcaatg
    14161 aaaggaagaa tggtttacgg aagcgcaagt tcaccccgaa gatagcaggc tctgtaatac
    14221 ctaggaaggc agaaagagca gccgggaaag caagtgtttt cagttttgga ttttttgttt
    14281 taacaccaac cgcaacagta gcagcacctt gagctgtcat agcagctgtg atgatagcgt
    14341 tgaatgggtt agcatggtca gcagcaagta attgcacttc aagcaagttg aagatgtggt
    14401 gcacacctga cacgacgatc aattggtgaa ccccaccaat caagaaacca ccaagaccaa
    14461 atggcatgct aagaatcgct tttgtagcaa taaggatgta gttttcaaca acgtggaaaa
    14521 ctggtccaat gacaaagagt ccaaggatag acatgaccaa aagtgtcacg aatggtgtta
    14581 ccaagaggtc aatgacatct ggaacaacct tgcggacagc tttttcaaat ttagctccga
    14641 caaccccgat gatgaaggct ggaagaacag aaccttgcaa accaacaaca gggatgaaac
    14701 caaagaagtt catcgctgtt acttcaccac cttgagcaac tgcccaagcg tttggaagtg
    14761 agccagagac aagcatcata ccaagaacga taccaacggc aggatttcca ccaaatacac
    14821 ggaaggttga ccacacaacc aaacctggca agatgatgaa ggctgtatct gtcaagattt
    14881 gtgtgtaagt tgcaaagtca cctggaagtg gcatttcaag agcgttgaaa agaccacgca
    14941 cacccatgaa gagacctgtc gctacgataa ctgggatgat tggaacgaaa acatcaccga
    15001 aagtacggat agcacgttgg aaccagttcc cttgtttagc aacttctgct ttcatgtcat
    15061 ccttagatga tgttggtaag ccaagtacaa caacttcatc gtacattttg ttaactgtac
    15121 ctgtaccaaa gataatttgg tattgccctg agttaaagaa agcaccttga actttttcca
    15181 agttctcaat cacttcttta ttgattttct cttcatcttt gaccatgaca cgtagacgag
    15241 tcgcacagtg ggcaacacta ttgacatttt cacgtccgcc caaggcatcg atgacttttt
    15301 ttgcaatttc ctgattgttc atttgcaaaa atctccttat ataacatttt gttcttgttt
    15361 gaaagcgatt ttattcgccc ttacgactat tattttatca tgttttaaaa atatgtcaag
    15421 cgttttgcag aaaaaatatt ctatctactt agtgggcaag ctttagattg attgtttttg
    15481 actgtttcat caggaatttc ttgaaaaata agtttgaaac cttggttaaa aagtctttta
    15541 tttcattatc tttcacattt tcgtaaaaat ttgattgatt tcctgtattt attttatgat
    15601 aatcgtttga cagttttttc tcttttttaa tataaaaggc ttgcattttt tatcgaaaac
    15661 agttactatt aaaagtgata agatttttgg aggaatgaat ggaatggaca actgagcgtc
    15721 gttacagact ttatcaagat tggacgcaag aagaaattca acatataaag gaaaatatgg
    15781 cacaatctcc atggcatact cattaccatg ttgagccaaa aacaggactt ctcaacgacc
    15841 caaatggctt ttcttacttt gatggcaagt ggatcctctt ttaccagaat tttccttttg
    15901 gtgcagccca cggtttgaaa tcttgggcac agctagaaag tgatgatttg gttcacttta
    15961 aagaaactgg aatcaaagtt ttaccagata ctccattaga tagccacggt gcctactctg
    16021 gttctgccat gcaatttggc gataacttat tcctatttta tacaggaaat gttcgcgatg
    16081 aaaactggat ccgtcaccca taccagatcg gtgctttgat ggacaaggag ggtaagatta
    16141 caaagattga caagatcttg attgaccagc cagcagactc tactgaccac ttccgcgatc
    16201 cacaaatttt taactttaaa ggtcaatact atgctgtcgt cggtggacag gacttggaga
    16261 aaaaaggctt cgtccgtctc tacaaggctg tcaataacga ctacacaaac tggcaagcag
    16321 ttggcgacct tgactttgct aacgaccgta ctgcctacat gatggaatgt cctaatctgg
    16381 tctttgtaga ggaacatcct gtccttctct actgtccaca aggattggat aagaaagttc
    16441 tagactacga taatatcttt ccaaatatgt ataagattgg ggcttccttt gaccctaaaa
    16501 atgccaaaat ggtagatgtg tctcaacttc aaaacatgga ttacggtttc gaagcctatg
    16561 caactcaagc cttcaacgct cctgatgggc gtgctctagc agttagctgg cttggtttgc
    16621 cagatgtttc ttacccatct gaccgttttg accaccaagg aaccttctct ttggtcaagg
    16681 aactcactat caaagacgac aagctctacc agtatccagt cgctgctatt aaggaccttc
    16741 gtgcttctga agaagccttc tcaaaccgtt cccaaaccaa gaacacttac gaacttgaac
    16801 tcaacttgga agctaatagc cagagcgaga ttgtcttact tgctgataaa gaaggtaagg
    16861 gactttcaat caactttgac cttgtaaacg gtcaagtgac agtggatcgt agccaggctg
    16921 gagaacagta tgcccaagaa tttgggacaa ctcgttcttg ccctatcgag aatcaggcta
    16981 ctactgctac aatcttcatc gataactctg tctttgaaat tttcatcaat aaaggagaaa
    17041 aagtattttc tggtcgtgtc ttcccacatg cggaccaaaa tggtatcctg atcaaatctg
    17101 gaaacccaac tggaatttac tatgaattag attatggtca caaaactaac tgatgtcgcc
    17161 aaacttgcag gcgtcagtcc tactaccgtt tctcgggtta tcaataaaaa agggtatcta
    17221 tctgagaaaa ccatccaaaa agtcaatgaa gccatgagag aattgggcta taaacccaac
    17281 aacctggctc gtagtctgca aggaaaatca gctaagttaa tcggcttgat tttccccaat
    17341 atttccaatg ttttctatgc agaattgatt gataaattgg aacaccaact cttcaaaaat
    17401 ggttacaaga ccatcatctg caacagtgaa catgattctg agaaggaacg cgaatacatc
    17461 gaaatgttgg aagccaatca ggtagacggc atcatttctg gtagtcacaa cctaggaatc
    17521 gaagactaca atcgtgtgac agcgccgatt atttcctttg accgaaacct atcgccagac
    17581 atccctgttg tctcctctga caactatgct ggtggggttc ttgctgccca aaccttggtc
    17641 aagacaggtg cccagtctat catcatgatt acagggaatg acaattctaa ttcgccaacc
    17701 ggactgcgcc acgctggttt tgcatccgta ctcccaaaag ctcctattat caatgtttcc
    17761 agtgactttt ctcccgtcag aaaagaaatg gaaatcaaga atatcttgac ccgggaaaaa
    17821 ccagatgcca tttttgcttc ggatgatttg acagctattc tggtcattaa aatcgctcaa
    17881 gaattgggca tttctgtccc aaaagagctc aaggtcatcg gctatgatgg gacctacttt
    17941 atcgaaaatt actaccctca attggctact atcaagcaac ctttggaaga gattgcttgt
    18001 ctcactattg atcttctctt gcaaaagatt gaaggcaagg aagtcgccac aactggttac
    18061 ttcttaccag ttacactatt accaggaaaa agtatttaaa cacaagaaaa ctcagaccga
    18121 ttcgtctgag tttttatgat cttaaatttt cgagatagcg ctgggctgtc tctaggttaa
    18181 aggttttatc tgagatgagg cgctctacta ggggagcaac ttcagattca ctagccccag
    18241 ctaggagagc tagggatttg gcctgtagtt tcatgtgacc ttgctggatg cccgtactta
    18301 ccaaggcttt gagggctgca aaattttgag caagaccgat ggacacgata atctgggcta
    18361 attctctggc agaaggattt cctagtagat catgactgag agctacacgt gggttgaggc
    18421 cgatagagcc acccttagtc gctacaggca tgggcagggt catctcaccg accaattctt
    18481 ctctttcaag gtccagcgtc cagcagctaa gaccttgata gcgtccatct cgactggcaa
    18541 aggcatgggc cccagcttcg atggcacgcc agtcattacc agtggcaatc aaaatcgcat
    18601 caataccatt aaaaattcct ttattatgag tagcagctcg gtaaggatca gcctgcgcaa
    18661 actgactagc caatgcaatt ttctccgcaa tctctcgtcc ttgatccttt tggcggctca
    18721 agtagcgaaa ggccatgcga cagcttgcag tcaccagaga atcggtcgcg tagttggaca
    18781 ggattcccat gagactctgt ccctgactga gttcttctaa gactggtttc aaggcttcca
    18841 gcatggtgtt gagcatattg gcacccatgg cttcctgggt atcaacatga atataaacaa
    18901 cgagaaagtc tggttcacct tttatctgct cgacatgcag gtcactcgcc ccacccccac
    18961 gtttaacgat agaaggatag gcttgattgg caagctccaa gagctccgct ttcttgctgg
    19021 caatcttctc ttgcgctagt ttaggattag caatttgata aagggctacc tgcccaatca
    19081 tctggcgctg atggacttgt gcagtaaaac cacctgcacg cttgatgatt ttgctggcat
    19141 agctggccgc cgcaaccaca gagggttctt ctgtcacata gggaacggtg tattcctgac
    19201 cgttgacaag tacctccgga accagcgaat aaggcagaga aaaagttccc accacattct
    19261 cactcagctg gtctgccaca gtcacactca tctgttcatc cttctccaga ctagcttgtc
    19321 tctcaggact aaggagcgcc tgagctttta gcagctcgag gcgctcttgg tatgattttt
    19381 tagaaaatcc attccaactt atcttcatta tttttcaacc ttgctataac ggcgttggtg
    19441 gtcaagaatt tcaaccaagg caaaatcttg attttcatag ccagcaaact gggcagagtt
    19501 tgtttcatcc aagtttactt cctcaaaaaa gaccttttca tagtctgcaa cggatagggc
    19561 agttcgttgg ttgagcttgt tcaagcggtc tttatccaaa taagcttcat atccttcaac
    19621 caattcacca ctgaagaact cagccacagc tccacttccg taactataaa gggcgatttt
    19681 atccccagct ttcaagctat ctgtattttc caagagagac aaaagtccaa ggaaaagtga
    19741 acctgtgtag atattcccca ccttttgact gtagagaata gactggtcaa aatgcttttg
    19801 taagaggtct tttttctctt gaggcaggct cttatccatg atttttttca agccttttag
    19861 cgctaattta ggataaggca agtggaaaca aacagccgca aaatcatcca gagtaagctg
    19921 gtagcgtttt tgatattcaa gccaagtcgt tttcaaacta tccaagtatt gttgggtaga
    19981 ataaacacca tttacataag gagttgtcga gtaatttggt cgccagaaat ccatgatgtc
    20041 acgggtctga gctacattgt cattattaaa ggccatcatg cgtggatttt gtgtaatcaa
    20101 catagctaca cttccagcac cttgagttgg ttctcctgga gtttcaatac cgtatttggc
    20161 aatatcactg gcaatgacca agaccttgga ctccggagaa ttttccacat gcaatttggc
    20221 ataatgaagg gcagcagtcg ctccataaca ggcttcttta atctcgaaac tacgagcaaa
    20281 gggctggatg cccagcaagc catgcacaaa gacggccgca gccttactct ggtcaattcc
    20341 tgactcggta gccacaatga ccatgtcaac ttcttgtctt tcttgctcag ttaaaataga
    20401 gtcactagca ctggccgcca aggtcacaat gtcctcagtt aggggcgcaa tactcaattc
    20461 cttgagtaag agtcctttac ttaatttttc agggtcaatt cccctcgctt ctgctaagtc
    20521 ttgtaatttc aagacatatt gactggtcgc aaaaccaatc ttatcaatac cgattgtcat
    20581 atttacctct gttttatcat tcatgtaaaa aatcgttcta tactatttta tcacaaatgg
    20641 cagtaaaaga gagaaaaaag acttgattca ccaaatcaag cctcttattg gtcatcattt
    20701 taaagaatga ttagttgcta gagagttcac cgatataagt agctttataa gctccattca
    20761 cagttatcag ctcctggagg atcaaatttc ctgagtaagt ccttcccatc tcatctacaa
    20821 atttttgata aaactgactg gtcggaattt ctctgacatc cttatcaaat gtcttatcaa
    20881 gtgttttact aaccttctca gcaatcaatt gatgctcttg ccatccactt tgaaactctg
    20941 agcccgaact agaaaccatg actgggataa acaacaaggt cagtagattt acagacaata
    21001 aggaaagtag tagacttcct gcaaaactag aatcctagtt catgattgat aataccagca
    21061 atcaaattca ttcgtaatcc gaagcgttta cgatgatttc gataggttgt tgaaaacatt
    21121 ttaaacgttt ttactttggc aaagatgttc tcaaccttgc ttctctcctt agatagcgca
    21181 tggttacagg ctttatcttc agctgttagc ggcttgagtt tgctggattt acgtggagtt
    21241 tgtgcttgag gatatatctt catgagccct tgataatcac tgtcagccaa gattttacca
    21301 gcttgtccga tatttctgca actcattttg aacaacttca tatcatgact atagttcaca
    21361 gcgatatcca aagaaacaat tctcccttga cttgtgacaa tcgcttgagc cttcatagcg
    21421 tgaaatttct ttttaccaga ataattcgct aattgttttt tagggcgatt gatttttact
    21481 tccgtcacat caatcattat cgtgtcctca aagctgagag gagttcttga aatcgtaaca
    21541 ccactttgaa caagagttac ttcaacccat tggctccgac ggattaagtt gctttcgtga
    21601 ataccaaaat cagccgcaat ttcttcataa gtgcggtatt ctcgcacata tagaaagcgt
    21661 tatcaattta tttatctcat ttttcagaaa attcttttat ttctgtaaag tctacgatac
    21721 tcgatgtgtt tttatataat gatagagtct gagaatcact gttccgctag ccattccaat
    21781 agagattacc aaagccaaca tgacaaccaa ggtcgcactt gccagtgctt tattatagtc
    21841 ccctgtcaca aaaaaggcag ttgttcggta ggagagataa cctggaacca gcggtgccaa
    21901 aatggccaag ataaagacca cagcaggtgt cttataaaga atacttaaaa tctggctgac
    21961 acaagaacca ataatggctg caatgaaggt agctacaatg acattggtcg gttccttgag
    22021 caagagatag attagccaga cagtcatgcc caaaatccct ccaggtaaga gcatagaccg
    22081 ttgcacattg agtacgatta aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa
    22141 taaaaaggtt gttagtgtca tattagttca tcaataccaa ggcgacagaa gttcctgccc
    22201 ctaaagcgag ggtaatgagc agggattcaa acatcttact cataccagag tttatgtggt
    22261 tggtcataat atcacggacc gcattggtca aggcaatacc tggtacaaac ggcatgaccg
    22321 caccagctat aatcaaatct gccgttgaag gaaaacctgt gtagcgagcc caaaactggg
    22381 caattatccc aaagacaaag gctccagcaa aggctgtcac aaagggaatt cggataaatt
    22441 tttccacata gagggaaaag gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt
    22501 cgtagatatt tccgctaaac ataactgaaa agaaaggagc actaaaggtc gcagccagag
    22561 ttacctgcaa cttagtatag ggaaggggtt tggcttgcaa ggccgtcaat tgcttaaagg
    22621 ctgtttctaa gtcaatctgc cccccaacta gctgacgaga aatctggttc acatcgcaga
    22681 ctttttcgat gttataagaa gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt
    22741 caatagagaa aaagatagcg gcaggcatgg caaggacatt gcaatccaca atcccctgcg
    22801 aatgcgcgat tcgaatcatg gtatcttcta cacgatggat ttctgagcca cttttaagga
    22861 gaatagtccc cgctagcata atcacatcaa tgacggcatt taattctttt gattcttcca
    22921 tgctttcctc cttttatcaa ctccctctat tctatcacaa atccggactc aaaaaaaatc
    22981 tttgccatga aatcatgaca aagattgatt actcattttg attatccatc tgcttttaag
    23041 gagtagctga agttgtttta ggtttgtaga ttgaaatctt gactctagtc ttatttaggt
    23101 ctaccttttc acctgctcta ggactttgtt caacaaccat gccttctaca ctacctgcag
    23161 gcgctgtcgt cacttctaca acttctatat tagcttcctt aatcccaaca atttgaatca
    23221 aattgttctt agtaaactcc aagctggaac caatgtaact cggcatggca acacttgtaa
    23281 cttttttagc tactgtcaag acaatttgag taggtttact cacatcataa gtcgttccgg
    23341 cacctggact ttgtttcata atcgttcctg gttcgctttc gctggactct tcttcctcta
    23401 tcttaatcaa attctcagga accttcttct gcttgagttc tgagattact tctgtagagt
    23461 tccgtccaat atagttccct aattgaatcg tcgtagcttt tttagctact gtcaaaacaa
    23521 tttgagttgc cttgctcaag tcataggtcg taccttctgg tagactttgc ttcaggaccg
    23581 ttccagcctc actctcattg gactcttctt cctcaatttt aatcaaatta tctggaactt
    23641 ttttctcttt taattccgcg ataacatcag aagatttccg gccgacataa ttactaattt
    23701 ggaaggattg tttgcctgat gagacaacca gattgatttt cgttccttct tttcgaccag
    23761 ttccagcgcc aggatctgta cggataatcc gcccttcttc caccttttca ctagcctctg
    23821 tcttctcctc accaatctca aaattggctt ttttgagcgt tgccttggcc tctgcaactg
    23881 tctgacctgc cacatccgga atggcaatgg ttgcaggagt tctggataag atccaaataa
    23941 gagaagctgc caccaataca aggctggcca acaaaatcag gtaacgcatc ttaaatctat
    24001 gttttttcgg tgcttgtggt tggtaagttt cctctgtcac agcctggctt gggtttttga
    24061 ttgatttgtg ttctgtctgc gcttgaacct taggaataga tgtcaaggta ctctgagaaa
    24121 ccttcggcaa ggtcttggta tctgccttgc tcgtttcatc aaagattaac ttactttcat
    24181 ttctacgatt gtaggacaag ctactagaca agtccacata catctctgaa accgatcggt
    24241 agcgattggt caacttttta gcagttgcct tgataataac attttctaaa gcctgaggta
    24301 cagatggatt ttctgcaata acggacggca ggggtttctg gaaatgctgg agggcaatgg
    24361 tcaccgcgct atccccgtca taagggatat ggcctgtcaa catctcatag aaaataatcc
    24421 ccatggcata gatatcactc tgcacagtcg ccttagaacc acgcgcctgc tctggtgaca
    24481 agtaatgaac tgagcccaac atcgagttag tctgggtcag acttgtctct gcaaaggcta
    24541 cagcaatccc aaagtctgtg accttggcag tcccatctgg tgtcaaaagg atattttgag
    24601 gtttcaagtc cctgtgaaca attcctcgag tatgggccaa gcgcatagcc aagagaattt
    24661 gtcccatgat acggacggct tcttcattag aaagaggata atgttccttg atatagcgtt
    24721 tgaggtctag tccagcaaca tactccattg caagatactg ttgaccgtct tcctcaccaa
    24781 tatctgttat ccgaacgata tgaggatggt ctagatctgc catagctctc gcttcacgct
    24841 gaaaacgagc tacagctatc gggtccgtct ggtagttggt cctcagaacc ttcactgcca
    24901 cttcttcccc atctaagatt aagtctttgg ctaggtaaac atccgccatg cctcctcgac
    24961 caatctgttt gacaatccga tagcgtccgg caaaaatctt gccgatttgg atcattcttc
    25021 atcctcctcg ttcatagaaa caagggcaac cgtaatgttg tctaaacctc ctgcattgtt
    25081 agcaaaacga acaagtgtct ccgttttatc tgctaaagga atatcactgg ttacaatatc
    25141 acgaatctca ctgcctgaaa tcatgttggt caagccgtca ctattgagca agagatagtc
    25201 acctgactca aggataactg tcccaaaatc aggctgaatt tcatcttttt gcccaataga
    25261 ctgggtgata atattttttt gcggatgagc ttctgcctct tctggtgtca attgaccagc
    25321 cttgagcaat tcattaacca aggaatgatc gctcgtcaac tgatggtatt cttctccacg
    25381 aatcaagccg atacgcgaat caccaatatg agcatagata gcctgattat caataatagc
    25441 aaggacttcc aaagtagttc ccatgcctct gtaagcttca tcctgaccaa gctggtgaat
    25501 cttttgattt tcaatttcta ggtaatgggc gaaccattca cgcacttcat tgactgtatc
    25561 gatctgggta tcaacccaag ctacacccag gtctgtgacc gccatttcac tagcgatatt
    25621 ccctgcacga tgacctccca tcccatcagc taaaataatc atggtacgtc cagctctatt
    25681 gacatagtgg ttgacatagt cttggttatt tgttcgtttc tgaccaacat ctgttaataa
    25741 tgaaatttcc atgtgtcagt tccttcctaa tccgatatct tgcgaaattg actgatgaag
    25801 aatccatcac ttccatacaa ttcaggtgta atgaggatac agccgtcttt catgatatcc
    25861 ttacattcat gttctagttt tacctgctcg aactcgggat gactctctaa aaaggcctta
    25921 acgacttgaa aattctcctc tgagacgata gtgcaggtgc tataagttat tataccacct
    25981 ttgcctagta tttgacaaac actacctaat atttctaact gaatttcctg caaggacgcg
    26041 aaatctgccg tttctttatt gtatttgata tctggttttc ggcgcaaaag accgattcct
    26101 gaacaaggag catccaccaa aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc
    26161 tttctggcat ccaatttttg agtttgaacc cgatcttcaa ctcccagacg ttgggcattt
    26221 tcttgaatta aatccaactt gtggtcgtac aagtccagag cagtaacctg acctgtcgta
    26281 agataagagg ctatatgggc tgttttccca cctggagccg cacaggcatc aagcactcgc
    26341 tcatcacctt gtaaatcaag cgtcggagca accagctgac tggactcgtc ttggatggta
    26401 atggctccat ccgcaaacaa attatgccct gcaaaatgcc cctgctcctt aaccagacca
    26461 gtggttgcta aaagggaatc attcgcctcc aacaaggctt ggatttcctc ttttcgactt
    26521 aggtctgtta cacgaatact ggctttgttt cgcactaaca ggctttcaaa gatggctttt
    26581 gctctctcct ctccgtattc ttccttgagt ttggcaacta gccaaactgg gagagaatag
    26641 gcaatggagt cacgcttgtt ttttcgcttg atgctagcaa tatctggcca gccttcacgc
    26701 aagatacggc gaaggagggc attgaccaat ttttcactgc cttttttacg aagtttggcc
    26761 aattccactg cttcattgac cacagcatga tctggaatct tgtccaaata gcggagttgg
    26821 taggcactca tgagaagaag gacatagagc cagctgtcta actggtctct gtcttcgata
    26881 aagtgggata ggtaccattc cagagtcagt ttacgggcta ccgttccata gaccagctcg
    26941 gtcactaagc ccttgtctgc tgccaaaagt tgactcccct ttagatgctt atttaaggcg
    27001 atatttgagt atgcttggtt cacaaaaaca tcctctagca ctgctagagc taaacttcta
    27061 gccgtttcta ctttagtcac caaatcgttc tcctacagtc aatgtacgtc caactccgtt
    27121 gaggaaggaa gcaatgtcca tcttaggctt accagctggc tgcacttgtt tgagggatag
    27181 agccccttca gccgttgcga caatcaattc tttcttgccg atagagagaa tctcacctgg
    27241 atttccctga ccttctactg gtagggcttc ataaatctta aagcggtcgc ccttaaggaa
    27301 agcatgggca acaggccagg ggttcattcc acgaatttgg ttaaagagtt gacgattggt
    27361 tttgttccag tccagttttt cttcctctgg ctttatattt ggagagaagg taacctgact
    27421 cgtatcctgc ggttcaggtt tgatatcacc agcaatatag gcaggcagag tgtccaaaag
    27481 caaatcacga ccaactagcg ccaatttttc aaacaaggtg ccaacattgt cctcatctgt
    27541 gatcggaatg ctgcgacgag aaatcatatc tcctgcatcc atttccttaa ccatttccat
    27601 gatggtcaca ccagcttcct catccccttg aatcaaggca taatggatag gcgcaccacc
    27661 acggtgtcta ggaaggaggg aggcatgaac gttgacagca aagtccatgc tatcaaggag
    27721 tttgcttggg agaaactgcc caaaagcagc agtcacaatt ccatctgctc ctagcttcat
    27781 aagttcttcc atctctggac ttccagataa tttttcaggt tggtagatag atagtcctgc
    27841 ttccttggca gcctgcttga ctggggtttc ttggataact tttttacgac caacagcacg
    27901 gtctggctgg gtcacaacgg ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa
    27961 gactgttgct gaaaagtcgg gggtccccat aaagattagt tttgtcatat cttctccttc
    28021 ttataaaaat tgctgcggct catggtcaat gctgagacgg agctcactat tttcccgttc
    28081 ttgagtcaag gccaagacct ggttgagggt cggccccagc tcatcttcta aacggtattt
    28141 aattaaaatc tggtaatgat agaggttgtg ggtacgggca atcggttttg gcgttggccc
    28201 cagaatggga ctggtctctg acaagcctga ccgcaaaatg ttcatgactt cataggcacg
    28261 tttgaaaacc tcttcttctt tcttgtgaga aagggtaata ccaatcgtga aatagtaagg
    28321 tggatagccg agttgtcgtc tgattcccat ttcataggca taaaagcctt cgtaatcttg
    28381 atccttggca aatcgaatag catagtgctg cgaattgtag gactgtatca agacttgacc
    28441 tgctttttca gcccgacctg ctcgacctgc cacctgagtc aagagctgga aggttctctc
    28501 agaagaacgg aaatcaggca gattcaaggc cgtatccgca tttagaactc cgactagggt
    28561 aacattggga aaatccaaac cctttgcaat catctgagta ccaagtaaaa tatccgcttc
    28621 ccctcgccca aactggtcaa gcaaggcttg gtgactgcct ttctttcgag tcgtatccac
    28681 atccatcctc aaaatgcgag cttggggaaa gagttctgct agctcatcat aagccttctg
    28741 agttcccgtc ccatagtaac gaatactgcg gctcttacag ttaggacaga cctgaggaat
    28801 atccttcgag aaaccacaat aatggcagtt catagtcttg gtatccatat gcaaggtcag
    28861 agaaatatcg cagttgggac aagtatccac cgtcccacac tcccgacaca tgacaaagct
    28921 agaataacca cggcgattga gcatgagaac cacctgctct tttttaacca gacggtcttg
    28981 gatagcctct agcaaaggag gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg
    29041 aaagtcaatc acttgaacct cagggattgt agccaaagga ttggcacgtt gggttagacg
    29101 taagtgttga tagacgcctt tgccagcacg tgcccggctc tctaagctcg gcgttgcaga
    29161 tccaagtacc agagttgctt gattatactg agcccgtaaa atagctacct ctctggcatg
    29221 gtaacgggga ttgctgtcct gcttataagc cgcttcatgc tcttcatcaa taatcatgac
    29281 acccagattt ttcagaggag caaagatagc agatctggca ccaacaacaa cttgggcatc
    29341 gccacgctcc accttgcgcc attcatcata cttttcacca ttggataatc ctgagtgaag
    29401 aatggctacc ttgtccccaa aacgtgctat aaaacgctcg gtcatctgag gagtcaagga
    29461 aatctcaggt accagcaaaa tagctgtctt gcccttatcc agggcacctt ggataatctg
    29521 caagtaaacc tcggtcttcc cacttcctgt aatcccttga agtagaaagg gaggttgaga
    29581 actgccaata gaactcacaa ccgcatcacg cgcctgtctt tgttctggat ttaactccaa
    29641 aggtctactt gcttcaattc cttcaaaata agcagccgag cgttgaactt ccttttggac
    29701 tatggtaaca gcaccttgat ccacaaagaa gttgacttgc tctcgcgagt aggactctaa
    29761 caagctagcc aaggaagcgc tctctggatg agacagcaga taatctctca gttccaactt
    29821 tttcttggca cgtgtagaaa tctcaacacc ttctaattgg gcatggtcaa cctcatacca
    29881 agactgggtc ttgaccttct tttgatcgac tgcctgatat tccagaccaa gcaggccttt
    29941 tctagtcaaa cgcatcattt cagcttgctt ggcaaggtct agtgaagaaa aggctagcga
    30001 atcttctgaa ccaaacaggc gcactcgttc ttcctgactc aagccttcca gaggatagag
    30061 aatcttgtca tagctagaat tcagaaaccc tggaagcatg gccttgagga tagagatttt
    30121 gtaggagaag acagatttgc gtaactcctc agccagccag agttgttctg gcgtgagaac
    30181 aggagaaaaa tccagcacct ctgcaatatc ttttaaatct tgctccatct cttctccatc
    30241 tgattgggac ttcaaaccaa gaacaatccc ttgaatcagg cgattaccct taccaaaagg
    30301 cacatgaacc cgcatcccaa cttccagcat tccctcaaat tcctccggaa tcctgtaact
    30361 atagggctgg tccgtctgca tcaagggcac atctacgata atcttagcta gggccatctt
    30421 ctcacctcct ccttgtcagc acattcttgc aatagaaaaa ataagattga gtccccccaa
    30481 ccttaaattt tttcaccatc ttctttttct ttagcaattt gctctttgat tttcttttct
    30541 tcttcttctt tgcggcgttt ttcttcttcg atacggcgac gcactgcttc acgttttcct
    30601 tctggatctg ggtgaattgt aacgtttcct gattcgattt cttctaaagc gcgaagagtt
    30661 gatttttcag acttgaaacc ttgagttgct ggggcacctg cttccaattc gtgggcacgt
    30721 tttgcttcca agattacgag tgaatatttt gaaggaacct tgtcgagcaa ggtatcaata
    30781 gagggtttta acatcatttg cttgtaccta ttttctaaat tttatcgggt agttggagat
    30841 tttggtaaca tctcctgata gtgaccaatg acacgatcca cacagaagtg ttctgcttca
    30901 atcacacatt tgacacgttc agcagctagg ggcacctgat cgttgacaat cgcataatca
    30961 tactcacgca tgagggcaat ttcttccttg gccttttcga ttcgttgggc aatcacttct
    31021 gcactatctg ttccacgacc taccaagcga tcttgcaatt catccaaatc tggtggtgtc
    31081 aggaagataa agacagcatc tggaaccttt ttcttgacct gaagagcacc ctgaacttca
    31141 atttcaagga aaacatcgat tcccttgtcc aaggtttcat tgacataggt cagaggagtt
    31201 ccatagtagt taccgacata ttctgcgtat tccaacatct gtccttgacg aatcagctct
    31261 tcaaattctt cacgagtacg gaagaaatag tcaacaccgt ccacttctcc aggacgttgt
    31321 gcgcgtgtcg tcatcgatac agaatattga aattggtttt cagaactctc aaaaatctct
    31381 cttctaaccg ttccttttcc aacccctgaa ggaccagaaa aaacgattag taagcctcgg
    31441 tctgccattg tgtctccttt tagtcaatct gtgaaataac atttctctag aataatggca
    31501 aaaagccaga ttatccttta cagtctttct atctagtgta acaaaaaagc agtaattttt
    31561 caactgctct ttcttattta tttagcataa tctactgcac gaagctcgcg aatcacggtt
    31621 accttgatat ttcctggata atcgagattg ttttcaattt tcttacgaac tttgtgagcc
    31681 aagattgtga ctttgtcgtc cttgattttt cctggattga ccatgatacg aatttcacgt
    31741 cctgcttgga gggcaaagct agtttgcact ccttcaaagc cgttagcaat ttcttccaaa
    31801 tcatggagac gcttgatgta gctttcaaga gactcactac gagcacctgg acgggctgcg
    31861 ctcaaggcat ctgctgcagc gacgataact gctatcacgc tctcagcttc aacatctccg
    31921 tggtgactag caatcgtatt caccacaact gggggttcct tgtacttacg ggccaattcc
    31981 ataccgattt caacgtggct accttcaacc tcatggtcaa tggctttccc gatatcgtga
    32041 aggaatccag cacgacgggc aagagccgca ttttcaccaa gttcgctcgc catgatacca
    32101 gccaacttag caacctcaat cgaatggcgc aaaacatttt gtccatatga agtacggaac
    32161 tgcaaacgtc ccataatctt catcaagtct ggatgaaggt ttggcgcacc aatttcatag
    32221 gcagcagcct caccgtattc acgaatctta ttgtcaatct cttgacggtt tttctcaacc
    32281 aactcttcga tacgagctgg atgtatacga ccatctttga gcaacatttc catagtcata
    32341 cgggcaatct cacgacgaat cggatcaaat cctgacaagg tcaccacttc tggtgtatcg
    32401 tcgataatca catcgacccc tgtcaaactt tcaaaggtac gaatgttacg accttcacga
    32461 ccaataatgc gtcccttcat agtatcgtct ggcagatgaa ctgttgagtt tgttgactcc
    32521 gctacatatt caccagcgat acgttgcata gcttgaacca agatgtcctt ggccattttg
    32581 tcagaacgtt ccttgacctc ttgctcagct tcgcgaatgc gactggcaat ctccctggtc
    32641 aagttttcct ctgtctgagc caagataata tctcgtgctt ctgcctgaga cagagcacca
    32701 atacgctcta gttctgcttc tttttgtctt tcgacttcct ctaattgctc ttcacgcgca
    32761 tcaaggtttt tcgctctatc agaaatactt tgttcttttt gttcaagtgt ttgttcttta
    32821 ctcgtcaaat tgtcgtcctt acggtcaagg ctagtagctc tctctgtcaa acgactttcg
    32881 atttgtttga gttcttgacg ttctgatttg aattcagcgt ccacttcttc acggtatttt
    32941 ctggcttctt ctttggcctc caatagtgct tcttttttaa gagacttgct ttcacgtttg
    33001 gcttcattaa caagtaaatc cgcttcacgc tcagcttgtc cacgtaaatt agttgcttct
    33061 tgttcagcat ttaaaagcat caactctgca gcttcctgag atgatttcat cttagctgag
    33121 atgctgacat atccaatgac taaaccaatg atgacggcaa aaacagcaat cgcaagcgac
    33181 atgatttcca tgtttttacc tcattttatt gttattccga atgacataca ttcttttaca
    33241 ttctaccata aaaaagtgat tttcacaaac ctaaaataga atatgttttg aggaaattag
    33301 tctgaatttt aggattacac ttccttggtt ttttaaggag ataagtcagt gccgctatca
    33361 aaaagttcca ccgaatttct accgctatgg attttctatt gttgtgccaa atagtgttcc
    33421 actagattca aacattttgc tttcaagtct ttgaaaattc actttaggaa atcacagctt
    33481 atcttcaaga tcaaatttgt cataaattaa ctttttttat ttagttgtat caatttattt
    33541 cttaag
//
LOCUS       DAVMJI010000025        30580 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.025, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000025 DAVMJI010000000
VERSION     DAVMJI010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30580
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.025"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..400
                     /locus_tag="VYR58_001380"
     CDS             <1..400
                     /locus_tag="VYR58_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV3622524.1"
                     /translation="KKYNSYFYLDASGNYVQNAWVGNYYLKSGGYMAKSEWIYDKNYG
                     SYYYLTSEGSYARNTWSGNYYLKSNGKMAKSEWVYDSNYKSYYYLTSEGSYARNTWVG
                     NYYLKSNGKMAVNERTPDGYRVDGSGKWVK"
     gene            487..1406
                     /locus_tag="VYR58_001381"
                     /pseudo
     CDS             487..1406
                     /locus_tag="VYR58_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            1541..2500
                     /locus_tag="VYR58_001382"
     CDS             1541..2500
                     /locus_tag="VYR58_001382"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV3622525.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            2597..3436
                     /locus_tag="VYR58_001383"
     CDS             2597..3436
                     /locus_tag="VYR58_001383"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV3622526.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(3484..3654)
                     /locus_tag="VYR58_001384"
     CDS             complement(3484..3654)
                     /locus_tag="VYR58_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV3622527.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            3775..4659
                     /gene="miaA"
                     /locus_tag="VYR58_001385"
     CDS             3775..4659
                     /gene="miaA"
                     /locus_tag="VYR58_001385"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV3622528.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            4652..5890
                     /gene="hflX"
                     /locus_tag="VYR58_001386"
     CDS             4652..5890
                     /gene="hflX"
                     /locus_tag="VYR58_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV3622529.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            5883..6506
                     /locus_tag="VYR58_001387"
     CDS             5883..6506
                     /locus_tag="VYR58_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV3622530.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            6521..7450
                     /locus_tag="VYR58_001388"
     CDS             6521..7450
                     /locus_tag="VYR58_001388"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV3622531.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            7471..8226
                     /locus_tag="VYR58_001389"
     CDS             7471..8226
                     /locus_tag="VYR58_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV3622532.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(8280..9188)
                     /locus_tag="VYR58_001390"
     CDS             complement(8280..9188)
                     /locus_tag="VYR58_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV3622533.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            9252..9521
                     /locus_tag="VYR58_001391"
     CDS             9252..9521
                     /locus_tag="VYR58_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV3622534.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            9521..9901
                     /locus_tag="VYR58_001392"
     CDS             9521..9901
                     /locus_tag="VYR58_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV3622535.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            9990..10217
                     /locus_tag="VYR58_001393"
                     /pseudo
     CDS             9990..10217
                     /locus_tag="VYR58_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10257..10982)
                     /locus_tag="VYR58_001394"
     CDS             complement(10257..10982)
                     /locus_tag="VYR58_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV3622536.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGKILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTILKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            11144..12985
                     /gene="typA"
                     /locus_tag="VYR58_001395"
     CDS             11144..12985
                     /gene="typA"
                     /locus_tag="VYR58_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV3622537.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            13005..13259
                     /locus_tag="VYR58_001396"
     CDS             13005..13259
                     /locus_tag="VYR58_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV3622538.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLLLAYFSVRDITLMPVKKSKRR"
     gene            13624..13923
                     /locus_tag="VYR58_001397"
                     /pseudo
     CDS             13624..13923
                     /locus_tag="VYR58_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            14006..16027
                     /locus_tag="VYR58_001398"
                     /pseudo
     CDS             14006..16027
                     /locus_tag="VYR58_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            16029..16670
                     /locus_tag="VYR58_001399"
     CDS             16029..16670
                     /locus_tag="VYR58_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622539.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            16774..18126
                     /locus_tag="VYR58_001400"
     CDS             16774..18126
                     /locus_tag="VYR58_001400"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV3622540.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            18130..19188
                     /locus_tag="VYR58_001401"
     CDS             18130..19188
                     /locus_tag="VYR58_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV3622541.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            19198..20418
                     /gene="divIB"
                     /locus_tag="VYR58_001402"
     CDS             19198..20418
                     /gene="divIB"
                     /locus_tag="VYR58_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV3622542.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKRLEEEQKKQEE
                     ESNRNQTNQRSSRR"
     gene            20651..21352
                     /gene="pyrF"
                     /locus_tag="VYR58_001403"
     CDS             20651..21352
                     /gene="pyrF"
                     /locus_tag="VYR58_001403"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV3622543.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            21386..22018
                     /locus_tag="VYR58_001404"
     CDS             21386..22018
                     /locus_tag="VYR58_001404"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV3622544.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            22198..22601
                     /locus_tag="VYR58_001405"
                     /pseudo
     CDS             22198..22601
                     /locus_tag="VYR58_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22697..23461
                     /locus_tag="VYR58_001406"
     CDS             22697..23461
                     /locus_tag="VYR58_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622545.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LLIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKRKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            23461..24213
                     /locus_tag="VYR58_001407"
     CDS             23461..24213
                     /locus_tag="VYR58_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622546.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            24223..24921
                     /locus_tag="VYR58_001408"
     CDS             24223..24921
                     /locus_tag="VYR58_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622547.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFLEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            24918..25565
                     /locus_tag="VYR58_001409"
     CDS             24918..25565
                     /locus_tag="VYR58_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622548.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(25645..26510)
                     /locus_tag="VYR58_001410"
                     /pseudo
     CDS             complement(25645..26510)
                     /locus_tag="VYR58_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(26522..27279)
                     /locus_tag="VYR58_001411"
                     /pseudo
     CDS             complement(26522..27279)
                     /locus_tag="VYR58_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(27280..27957)
                     /locus_tag="VYR58_001412"
     CDS             complement(27280..27957)
                     /locus_tag="VYR58_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV3622549.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(27917..28597)
                     /locus_tag="VYR58_001413"
     CDS             complement(27917..28597)
                     /locus_tag="VYR58_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV3622550.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFG
                     NPSTLSGK"
     gene            28812..28958
                     /locus_tag="VYR58_001414"
     CDS             28812..28958
                     /locus_tag="VYR58_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV3622551.1"
                     /translation="MSYKTSNAEGHVDFINTYDLETMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            29086..30576
                     /gene="lysS"
                     /locus_tag="VYR58_001415"
     CDS             29086..30576
                     /gene="lysS"
                     /locus_tag="VYR58_001415"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV3622552.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
BASE COUNT         9178 a         5570 c         6704 g         9128 t
ORIGIN      
        1 taaaaaatat aattcatact tctatctaga tgcatcagga aattatgttc aaaacgcttg
       61 ggtaggtaac tattatctca aatcaggcgg atacatggct aaaagtgagt ggatttatga
      121 taagaactat ggttcatact actatctaac atcagaaggc agctacgctc gtaacacttg
      181 gtcaggcaat tattatttga agtcaaatgg taagatggct aaaagtgagt gggtatacga
      241 tagtaactac aaatcatatt actacttgac atcagaagga agttatgctc gtaacacttg
      301 ggtaggcaat tactatctta aatcaaacgg taaaatggct gttaatgaac gtacaccaga
      361 tggttatcgt gtagatggtt caggtaaatg ggttaaataa gaaactaaaa aataggataa
      421 taggtaatat cagatgaata aaaaaaatta ttttcatgtg ctttagcatt ttcaacgatt
      481 ggaacattgt caacgattga taaatcagga gttcttcctt tttcagcgca aacggtgcag
      541 gctgacatac aaacgcttac cccaatggca aaatattata ttattcttcc gaaggatgca
      601 gaaatatata aaacttggag aggtactgtc aatattccca ttattgatgc tacaaaaact
      661 actccagaat tatcttattt caaagaagat catcgcaact atatagctaa tgagaataag
      721 tctggtgcca attacataga gtggaaggga acagtagaag agtttaaaga ggccattaag
      781 aagttgactg ataaaaaatc aactactgca acaccaaaaa aggatgaaaa gccaacacca
      841 aaaccggatg agaagccaaa accaacacct acagttcagt ctggttgggt aggttcatcc
      901 tattatcaag atggtaaaaa agtcattagt aagtggattt ttgataaaaa atataattca
      961 tacttctatc tagatgcatc aggaaattat gttcaaaacg cttgggtagg taactattat
     1021 cttaaatcag gcggatacat ggctaaaggt gaatgggttt atgatgccac ctatcaagct
     1081 tggtattatt tgacatcaga tggttcttat gcttacagta catggcaagg aaattactat
     1141 ctaaaatcgg atggtaaaat ggctgtcaat gaatgggttg atggtggacg ttattatgtt
     1201 ggcgctgacg gagtttggaa ggaaggtcaa gcaagtacag cttcttctag taatgatagc
     1261 aatagtgaat attctgctgc tttaggaaag gcaaaaagtt ataattcgtt attccacatg
     1321 tcaaaaaaaa acgtatgtat agacaattaa cttctgattt tgataaattt tcaaatgatg
     1381 cagctcaata tgccattgat cattagatga ttaacagata ctggtaggcg aaaaaattcc
     1441 ttataattca tttacgcaaa cctttgcata agtgaatgga ttttgatata ctagtactgt
     1501 aagcattttc aattactaca caatgaaaaa ggagaatatg atgagtcaaa agattattgg
     1561 gattgacctt ggtggaactt ctatcaaatt tgcaatctta acaacagcag gagaaatcca
     1621 aggaaaatgg tcaatcaaga ccaacatttt ggatgaggga agtcatatcg ttgatgatat
     1681 gattgagtct attcaacatc gtttggactt gcttggattg gcagcagcgg acttccaagg
     1741 cattggaatg ggatcaccag gtgtggttga ccgtgacaaa gggactgtta tcggtgccta
     1801 caacttgaac tggaaaaccc ttcaaccaat caaacaaaag attgaaaaag ctttgggcat
     1861 tccatttttc atcgataatg atgccaacgt agcagctctt ggtgagcgct ggatgggtgc
     1921 tggagataac caaccagacg ttgtctttat gacactcggt actggtgttg gtggcggtat
     1981 cgtcgcagaa ggcaaattgc ttcacggtgt tgctggtgca gcaggtgagc ttggtcacat
     2041 cactgttgac tttgaccagc caatctcatg tacttgcggt aagaaaggct gccttgagac
     2101 agttgcttca gcaacaggga ttgtcaactt gactcgtcgc tatgccgatg aatacgaagg
     2161 cgatgcagcc ttgaaacgct tgattgataa tggagaagaa gtaactgcta agactgtctt
     2221 tgatctcgca aaagaaggag acgaccttgc tttgattgtt taccgtaact tctcacgtta
     2281 cttgggaatc gcttgtgcta acattggttc aatcctaaac ccatcaacaa tcgtcatcgg
     2341 tggtggtgtg tcagctgcgg gagaattcct tctacaaggt gttcaaaaag tttacgatga
     2401 aaatagtttc ccacaagtac gcacatctac taaattagct cttgcaactc taggaaatga
     2461 cgctggagtt atcggagcag catcacttgt attgcaataa gataatgaga gaggaaaatg
     2521 ctaacctaga gttagtaatg ttcctctttt attttttatg ctatactagt taggacaatg
     2581 aatgaggtga gagtaaatga caaaagcaga tacgattttt aaagagaata ttgaatgcat
     2641 tctaaaggaa ggtgttttct cagagcaagc tcgtcctaag tacaaggatg ggactgttgc
     2701 taattccaag tatgtaactg gtgccttttc cgagtacgac ttatctaaag gagaatttcc
     2761 tatcacaacc ttgcgtccca ttgcaatcaa atccgccatc aaagaagttc tctggattta
     2821 ccaagaccag tcaaatagct tagaagtgct taatgacaag tacaatgttc actactggaa
     2881 tgactgggaa gttggagaca cgggaaccat tggtgagcgc tatggtgccg ttgttaagaa
     2941 acacgacatt atcaataagc ttctcaaaca gttggaaacc aatccttgga atcgccgcaa
     3001 tattatttcg ctctgggatt accaagcttt cgaagaaaca gatgggctgc tcccgtgcgc
     3061 ctttcagacc atgtttgatg tccggcgtgt tgatggggaa atctatctgg atgcgacctt
     3121 gacccagcgc tccaatgata tgctggtggc ccaccacatc aacgctatgc agtatgtggc
     3181 tttacagatg atgattgcca aacattttgg ttggaaggtt gggaagttct tctatttcat
     3241 caacaacctc catatctatg ataatcaatt tgaacaagct caggaattgc tccgtcggga
     3301 gccgtcaaac tgccaaccac gcttggtttt aaatgttcct gatgggacta atttctttga
     3361 tatcaaagca gaagattttg agttggtgga ttatgaccct gttaagccac agttgaagtt
     3421 tgacctagct atttaaaaga atagaaaaaa gaagttgaga ataatcccaa cttcttttgt
     3481 ttcttaacgt gatacgcggc gacgagctgc ttttttacga ttttcttcga tgaaagctgc
     3541 tttttgctct tctggttcga ttactttctt tttaaatgcg tatactgcac ctgcaacggc
     3601 agcgacagtt cctgcgacac ctgttacaag acctttagcg aatcctttag ccatgagtct
     3661 tcctccttta tattctcaat cagccagcct cctcaagagg tcacattttt ctgactgacc
     3721 tttttgtgtt ataataatag taacgaaaaa atgggaattt ttcaaggaaa aaagatgaaa
     3781 acaaaaataa ttgtgattgt tggaccgact gctgttggaa agacggctct agctattgaa
     3841 gttgcaaagc gctttaatgg cgaagtggtt agtggagata gccagcaagt ctatcgagga
     3901 cttgatattg ggacggccaa ggctagtcca gaagagcagg cagctgttcc tcatcattta
     3961 atcgatgtta gagagataac cgagtcttac tcggcttttg attttgtttc agaagctaag
     4021 atgactattg aggatattca gagccgtggc aagctagcca ttatcgccgg tgggactgga
     4081 ctttatatcc agagcttgct agaaggttac cacctaggtg gggagactcc tcatgaggag
     4141 attttagctt atcgagctag tttggagcca tattcagatg aggaattagc ccatttggtg
     4201 gagcaagcag gccttgagat tccccagttt aatcgtcgtc gtgctatgcg tgccttagaa
     4261 attgcccatt ttggtcagga tttggaaaat caagagatct tgtatgaacc gctgattatc
     4321 tgcttggatg atgaacgtag tcaactttat gagcgtatca accaccgagt ggatttgatg
     4381 tttgaggctg ggcttttgga tgaggccaag tggctgtttg accattcccc taatgtacag
     4441 gctgctaaag gaattggcta taaggaactc tttccttatt tccgtggaga gcagaccttt
     4501 gaggaagctc gtgagagtct taaacaggcg acccgtcgtt ttgccaagcg tcagctgacc
     4561 tggttccgta atcgcatgca ggtcaccttt tatcagattg gagaatctgg tgtacaagac
     4621 cgcattttaa gccagataga ggagttttta gatgattgaa acggagaaaa aagaggagcg
     4681 agtcctgctg attggtgtgg aattgcaggg tatggacagt tttgacctct ccatggaaga
     4741 attggctagt ttagcgaaaa cggcaggggc agtcgttgta gatagctaca gacaaaaacg
     4801 tgaaaaatat gattccaaga ccttcgtcgg ctctggtaag ttggaagaga ttgcgcttat
     4861 ggtggatgca gaagaaatca ctactgtcat cgtcaacaat cgtctgaccc caaggcagaa
     4921 tgtcaatcta gaggaagttc tcggtgttaa ggtcattgac cgtatgcagt tgattttgga
     4981 tatctttgcc atgcgggctc gaagccatga agggaagctc caagtccacc tagcccaact
     5041 caaatacctc ttgcctcgct tggttggtca ggggattatg ctcagccgtc aggcaggggg
     5101 aattggttcc cgtggtcctg gtgaaagcca actggagctg aaccgtcgta gcgttcgcaa
     5161 tcaaatcacg gatatcgagc gccagcttaa ggtggttgag aaaaatcgtg cgactgtcag
     5221 agaaaaacgt ttggagtcta gcacttttaa gattggtttg attggttata ccaatgctgg
     5281 gaaatcaact atcatgaaca tcttgaccag taagacccag tatgaagcag atgagctctt
     5341 tgcgactctg gatgcgacaa ccaagagtat tcatctggga ggcaacctcc aagtaacttt
     5401 gacagatacc gttggcttta tccaagattt gccgacagag ttggtgtcca gtttcaagtc
     5461 aaccttggaa gaaagcaagc atgtggacct tctggttcat gttatcgatg ctagcaatcc
     5521 ttaccacgag gagcatgaaa aaacggttct ctccatcatg aaagacctgg acatggaaga
     5581 tattcctcac ttgacgcttt ataataaagc ggatttggtg gaggatttca cgcctaccca
     5641 aacgccatat accctcattt ctgccaagtc tgaggacagt cgtgaaaact tgcaagcatt
     5701 attgctagat aagattaagg aaatttttga agcatttacc ctgcgagtgc ctttttcaaa
     5761 gtcctacaag attcatgatt tagagagtgt tgcaattctg gaagaacgtg attatcagga
     5821 agacggcgaa gtgattacag gctacatttc cgagaaaaat aaatggaggt tagaagaatt
     5881 ttatgactga tattaaaact ttggctctaa agtatggagg ttatacaagt ctggacaagg
     5941 tctatctgga tcagcttcta gctggtaaaa cagatcagga gcagttaaca cttattacac
     6001 ctccgccaag tgttgttaat gcctactttg cagaactcta tcagaaaaag agtcctcagg
     6061 ctgcgacgga ttattttgca gaactcagtc aggaactgaa tctttacaat actgagccaa
     6121 gtttcaccct agaaaataag ccttttattc ggcttaatct gtctggtaaa tcctttggtt
     6181 tttgttatga gagtgacggc cttggtcgga ttttctttga aaatgaggag aaaatctcgg
     6241 atgacttgct ctttgaaatt gcgcaaattt tcccccatca attagtcttt gaagagtctg
     6301 gtaagattta catgaagcct gtcgaggacg aggaagttat cagcctagaa agtctcacag
     6361 ctttgactga tttggaaaga ttggctgatg gtcgaaaacg tctcaaaggc tacagccaag
     6421 aggatttatt gcaagaagct gctgcttttt ctggcaaacg ctatttccga tcggaaaacc
     6481 gcacagccat gttatatatt gattaattag aaagtatcga atggatattc aatttttagg
     6541 aacgggggct ggtcagccct ctaaagcccg caacgtttca agtctcgccc tgaaactttt
     6601 ggatgagatt aacgaagttt ggctctttga ctgtggagaa ggtacgcaaa atcgcattct
     6661 ggaaaccaca attcgaccac gtaaggtcag caaaatcttt attacccatc tgcatggaga
     6721 ccacattttt ggtttgccag gtttcctttc tagccgtgcc tttcaggcca atgaagagca
     6781 gacagatttg gaaatctacg gacctcaagg aatcaagtca tttgtcttaa ccagccttcg
     6841 tgtgtcaggt tctcgtctgc cctaccgcat tcatttccat gagtttgacc aagattctct
     6901 gggtaaaatt cttgaaaccg ataaattcac tgtgtatgca gaggagctgg accacactat
     6961 tttctgtgtt ggctatcgtg tcatgcaaaa ggatctagaa gggacgctgg atgctgaaaa
     7021 actcaaggct gctggtgttc cgttcggccc gctttttggt aaaatcaaaa acggccagga
     7081 tcttgttttg gaagacggaa ctgaaatcaa ggcagcagac tatatctcag cgccacgtcc
     7141 aggtaagatt atcactattt taggagacac tcgaaaaacg ggtgccagtg tgcgtctggc
     7201 tgtcaatgca gatgtcctag ttcatgagtc cacttatggc aagggtgatg aaaaaattgc
     7261 tcgtaaccat ggtcactcaa ctaatatgca agctgcacaa gtagcggtag aagcaggtgc
     7321 caaacgcctc ctactcaacc atatcagtgc ccgtttcctc tcaaaagata ttagcaaact
     7381 caagaaagac gctgccacaa tttttgaaaa tgtccatgtg gtcaaagact tggaagaagt
     7441 ggaaatctag cagtcacaga aaggataagt atgcctacta ttctcattac cggagctagc
     7501 ggtggtctag ctcaagaaat ggtcaaactc ctgcccaatg accaactcat cttgcttggt
     7561 agaaataagg aaaaattagc ccaactctac ggaaattatt cccatgcaga attgattgaa
     7621 attgatatta ccgacgattc agccctagaa gctctggtaa ctgatcttta tctccgctat
     7681 ggcaagattg atgtcttgat taacaacgct ggttacggga tttttgaggg atttgaccag
     7741 attgctgata aagatattca ccagatgttt gaggtcaata cctttgccct gatgaatctg
     7801 tctcgtcacc ttgcggctcg tatgaaggaa agcagcaaag ggcatatcat caacatcgtc
     7861 agcatggcag gtctaatagc tactggcaag tctagtcttt actcagcgac caagtttgcg
     7921 gctattggtt tttcaaatgc tctgcgactc gaacttatgc cctatggagt ctatgtgaca
     7981 acagtcaatc caggtccaat ccgaacagga tttttcgacc aagccgaccc agatggaact
     8041 tatcttaaat cggttgaccg cttcctgcta gaaccagatg cagtggctaa aaagattgtc
     8101 aagattatag gaaaaaacaa acgagaactc aatctcccga ttttgttgaa cctagctcat
     8161 aagttttata ccctctttcc taagctagct gataagttgg caggggaaac ttttaattat
     8221 aagtaaaaag aaccaatgtg caggttgttg ctagcctaca tattggttct tatcatttct
     8281 caactatcaa actgaacttc ttctaggaga tagtctataa agcgttcgcc catcttagat
     8341 aggctggttt tctcatgctg gatatagacc agctcgatcg ggtcatcaat atccagtggg
     8401 atagaaacga tattgtctcc gtttaggttg ctgttcaaaa tccctgtcgc aatggtataa
     8461 ccatccaaac caatcaagag attaaagagg gtggcacggt cactgaccac aatggatttc
     8521 ttgtggtgtt cttgagaaag aatctcttct gaaaagtaga aggagttgtg cgtcccttgg
     8581 tcatagctga ggtaagggaa attctccaaa tcagacagtt tcaccttgtc tttctttgcc
     8641 agagggttgg tcttgctgac aaagatatgt ggttgcgctg tgaagagatg gtgggctagc
     8701 aggtgattgt catccagcat cttggttaaa acatcacggt tgtaactgtt taagaagagg
     8761 accccgacct cactgcggaa gttcttgacg tcgtcgataa tctcccaagt ccgagtttca
     8821 cgaaggaaga gttcgtattt ctccatatcg cttttcttga gcaaagagac aaaggcattg
     8881 accacaaagg catagtgttg agacgaaacg ctaaatagtt cgcggtgggc gacaggattt
     8941 ttatagcgtt cctccagaag ctgggtctgc tcgacaacct gacgggcata agagagaaac
     9001 tccatcccat cacgggtcaa ggtgattccc ttgggattgc ggataaagat ctcaatgccc
     9061 atttcatttt ccaaatctcg cactgcattg gagagacttg gctgagtgat aaagagttgc
     9121 ttggctgcct cattcatgga gccagtttcg acgattttga taatataatg taattgttga
     9181 attctcatgt ttttattgta ccatacttgc cttagaatcg ctaaagaaga taggaaaata
     9241 aggagcattg tgtgagtctc ttcttgaaaa aaacacaaaa ttttgctaga atgagtctta
     9301 tgaaaacatt ctatgatgtg cagcaattcc tcaaacgatt tggtattatt gtttacatgg
     9361 gaaaacgctt atatgatatt gaactgatga agttggaact atctcggatt tacgatgcag
     9421 ggttgatgga taaattagac tatctagagg cagaagcagt tcttcgcaga gagcacaagg
     9481 tagaattgga ttatattgag aaaaatggag aaaagaacta atggttactt ggattttgtg
     9541 ggcacttata ctagcaatgt tggcgtggat gggctttaac tatcttcgta ttcgccgtgc
     9601 ggctaaaatt gtggacaatg aggagtttga agccttgatt cgtacgggtc aattgattga
     9661 tttgcgcgac ccagcagaat tccacagaaa acatatcctt ggtgcacgca atattccttc
     9721 aagtcagttg aaaactagtc ttgcagccct tcgtaaagat aaacctgtcc ttctctacga
     9781 gaaccaacgt gcgcaacgag ttacaaatgc agctctttac ttgaaaaaac aaggtttttc
     9841 tgagatttat atcctttctt atggcttgga ttcttggaaa gggaaagtga agactagcta
     9901 accttatttc caaattagtc gaatgatagg atgaagctat tgttttatag tataattaat
     9961 ttgtataaaa tttaaggagt tcttagaaca taaaagaaaa gaagaaaaat ccactttttg
    10021 tgggtatctt gtcgattatt cttggtttgt tatttccaat tgtaggcctg attttgggta
    10081 tcataggatt ggtcttggct atttcatacc aaaaagagtc ataattagac tataaaatag
    10141 aaaagattct taatatctta ggaattgtga tttctgtagt taactggatt gtagcaatcg
    10201 ccttaatttt tcggtaaata aaagaaaaaa gctttagttt taaagctttt tttgttttat
    10261 cgactcatct ctaaatagtt tttaatgatt tgtaactctt tttggttcaa agggcggtag
    10321 ttactttctg ctaaatctgg gttcaatgtg aagtccccaa attggattct cttgaggata
    10381 gtcaccttaa caccaaccga gaggaacatt ttcttgattt gatgaaattt tccttctgaa
    10441 atggtgatag aggcttgact gatggaggga cttgcagata gaatctctag ttttgcgggt
    10501 ttacagacag taccatctaa aaagacaatt cccttttgaa aggcttggat atggtcaggt
    10561 gttagaagtc cattaacctc aacttgataa gtcttatcga catgatattg gggatggagg
    10621 agttggaagc ccaagggacc gttatcggtc aagaggagga gtcccgttgt atctcggtcc
    10681 agtcggccaa cggcatagag cttgtcagac tggatgtcag atggaagcag gtccatgacg
    10741 gtcggaagtt ccttgtcttt gttggctgta acgacaccag caggtttatg aagcataaga
    10801 taggtgtgtt catagccttg aatgattcga tcctgaaaaa ggagttcttg tagtcctgta
    10861 tcgatatttt gagctaggga gcgggctggg caaccatcga ctagaatttt ccctctgagg
    10921 agtgcttgct tcatggcctt tcggctgatt ttttcttggg ctaataaatt atctaaacgc
    10981 atactgtgcc tatcttatca taagtcgctt gctttgaaaa ggcttgacgt gaaaagaaaa
    11041 gcggagtgaa aacatttaca cttgcttgag ttatgttatt tatttgaaat tatggtataa
    11101 tcgttcagtt agaaaataaa ttttgaatat tatagaggaa atcatgacaa aattaagaga
    11161 agatatccgt aacattgcga ttatcgccca cgttgaccac ggtaaaacaa ccctggttga
    11221 cgaattattg aaacaatcag aaacgcttga tgcacgtact gaattggcag agcgtgctat
    11281 ggactcaaac gatatcgaaa aagagcgtgg aatcaccatc cttgctaaaa atactgccgt
    11341 tgcttacaac ggaactcgta tcaacattat ggacacacca ggacacgcgg acttcggtgg
    11401 agaagttgag cgtatcatga aaatggttga cggtgttgtc ttggtcgtag atgcctatga
    11461 aggaaccatg ccacaaactc gtttcgtatt gaaaaaagcc ttggaacaag accttgtccc
    11521 aatcgtggtt gttaacaaaa tcgataagcc atcagctcgt ccagcagaag tagtggatga
    11581 agtcttggaa cttttcatcg agcttggtgc agatgacgac cagcttgatt tcccagtggt
    11641 ttatgcttca gcgatcaacg gaacttcttc attgtcagat gatccagctg accaagaagc
    11701 gactatggca ccaatctttg acacgattat cgaccatatc ccagctccag tagataactc
    11761 agatgagcct ttgcagttcc aagtgtcact tttggactac aatgacttcg ttggacgtat
    11821 cggtatcggt cgtgtcttcc gtggtacagt taaggttggg gaccaagtta ccctttctaa
    11881 acttgacggt acaactaaaa acttccgtgt tacaaaactc ttcggtttct ttggtttgga
    11941 acgtcgtgaa atccaagaag ccaaagcggg tgacttgatt gccgtttcag gtatggaaga
    12001 catctttgtc ggtgaaacca tcactccgac agatgcagta gaagctcttc caatcctaca
    12061 catcgatgag ccaactcttc aaatgacttt cttggtcaac aactcaccat ttgctggtaa
    12121 agaaggtaaa tgggtaactt ctcgtaaggt ggaagaacgc ttgcaggcag aattgcaaac
    12181 agacgtttcc cttcgtgttg acccaactga ttcaccagat aaatggactg tttcaggacg
    12241 tggagaattg cacttgtcaa tccttatcga aacaatgcgt cgtgagggct atgaacttca
    12301 agtatctcgt ccagaagtta tcgtaaaaga aatcgacggt gttaaatgtg aaccatttga
    12361 acgtgtacaa atcgacactc cagaagaata ccaagggtct gttatccaaa gcctttctga
    12421 acgtaaaggt gaaatgttgg atatgatttc aactggtaat ggtcaaactc gtttggtctt
    12481 ccttgttcca gcgcgtggtt tgattggata ctcaactgag ttcttgtcaa tgactcgtgg
    12541 ttacggtatc atgaaccata ccttcgacca atacttgcca ttgattccag gggaaattgg
    12601 tggacgtcac cgtggtgccc ttgtttctat cgatgctggt aaggctacaa cttactcaat
    12661 catgtctatc gaagaacgtg gtacgatctt tgtcaaccca ggtactgagg tttatgaagg
    12721 aatgatcatc ggtgaaaact ctcgtgaaaa tgacttgaca gttaacatca cgaaggcaaa
    12781 acaaatgacc aacgttcgtt cagctactaa ggaccaaaca gctgttatca agacgcctcg
    12841 tatcttgaca cttgaagagt ctcttgagtt cttgaacgac gatgagtaca tggaagtaac
    12901 gcctgagtct atccgtttgc gtaaacaaat ccttaacaaa gcagagcgtg agaaagctaa
    12961 caagaagaaa aaatcagctg aataagagct agaaagagag aaagatggtc tatttagtcc
    13021 taggaatttt actgctccta ctctatgtat ttgcgacacc agaaagcatt aaagggacag
    13081 tcaatatcgt cgctatggta tgtattttag tggcactctt gattttattg gttctatctt
    13141 ttctgaaaat ttttcaatta ccaacagaaa tattcctagc aatagccatg ttgctcctag
    13201 cttactttag tgttagagac attacactca tgccagtcaa aaaaagtaaa agaagataaa
    13261 aaagagagtt ttggctctct tttttgctag gaattttaca agattgcaat ttatttttga
    13321 gttatcacca tctcttttgt ttggataata tgaatgggaa aaacttgaat aaaattcgtt
    13381 aatggaatct attttatatt tggttagtac tggttgcata ttattttgaa ataaaactac
    13441 tatataatat tattcataga ggtaatatag taaaatatct aaaaaattcg attttttcct
    13501 tgacaacaaa taataaaaat gttattctta tcacataaga aagcggtttc aataaaagag
    13561 agaggaggat ttattttgtt gcattgttgc tcaaggtgtg atttttttga aagaaaaaat
    13621 aaaatgaaaa cgaaaaaaca tagattactt gctctagctc ttatttcaag ttttacatta
    13681 ttgggagctg catcagctgc tgtataatat ccagatggag gagtatggac atatggagaa
    13741 ggttcaggag gtggttaggc tttttcaaat tactatcatg gtaaaaaata tcattattca
    13801 tccatcgtga gcagatggga tggtcattct gataaaggag aagctcctgc tggaaaaacc
    13861 tcctatgcat ggatttggac taaatgggga gaacaagtag cattttactg tgattatgac
    13921 taatcgttca ttgatttaaa tcgttcccct tgtaagaaat tacaggggga attttgttta
    13981 caaggagtct accaaggagt ctactatgaa gaaactattc atattattat caactttttt
    14041 tctcagcttc ttccttgctt ggattattgt cttacgtgcg ccacaatatt tatatgcaag
    14101 ctatgattcc gtttctttac ttcgtgtcaa aaaagatact caggaaccga cgcgtgaggt
    14161 atttgaacag gaattggaga attttgcaaa ctcagaacag agtttaatag ctagaagaat
    14221 tgtagagccg agtaaggatg ggacgactca ctttacttat gcaacttatg gtcagggaac
    14281 tttaccaaaa gaattccaag aagctagcca agaaagtcgt gaacgtagtg atccgctaaa
    14341 tagttatctc cttttgtcag gctccttgac gaaagaaaag cttgccgata aattaggaga
    14401 tttgggttat aaagcaagtg ctgaccgaaa gataccgccc tattttcttg cttttcgaat
    14461 attactaaat ccccttattt taattagttt agcaatattt ggcttatctt tctttgcttt
    14521 agtgattatc actcggatta aggaaatgag agcagcaggt ataaaactct tttctggtca
    14581 gactctctta tccatcatgg ggcattcttt atctactgat atcaaatagc tccttctatc
    14641 agccctcctt tccttcctag gtgggggagt cgttcttttt agtcaaggtt tgttttatcc
    14701 tatcttgtta gccacctatg gttttgggat tagtttctat ctgttgtttt tattggcgat
    14761 ttcaatttta ctaatgcttc tttatctaat gagtttgagt tacaaagcat tagttcccgt
    14821 tattaagggg agattacccc ttaaacgcct gatgatttta accctattgt gtcagttggt
    14881 tgctgtcttt acagtaggat acgctgttaa gacaggtttg acgtcttacc aacgattgaa
    14941 agaacttgaa atttcaaaac aagcatggca ggatagagca gactattatc aaatttcttt
    15001 tggcttaggt gatagaggaa aagatacaga aaatcagagc aagtggtatg cctttgccaa
    15061 ggaagcaatc gaagaggaac aagctcttta tgtaaaggat aatctgctcc attttgccaa
    15121 tccacaagga aaaaatgaac agggagagac actggatacc tatagtccag atgctaatac
    15181 gctctatgtt agtcccagtt atttggacaa ggaaaaggtc gtggtagatg ctgagaccaa
    15241 acagaagtta gcccatctcc aaaaaggtga gtttatcctc ttgctcccag aacatttgcg
    15301 ctctcgagaa gcagaactta agaaagtttt tgaagaaaga ttgagttatt atggaaaatc
    15361 tggtgaggag gcaagtgctc ctttggatta tgagatgaaa gcgcacgtta gttatctttc
    15421 aatgggagaa aagcggtttg tttataataa cggtgagaat cccgtatcta ctcagtattt
    15481 gactgatccg attttagtgg tattcacgcc gacttctaca ggtgatagtt ttatatcctt
    15541 atctagttgg tctatcaatg ctggaaaaca actctttatc aaaggatatg agagtgggct
    15601 agaactcttg aagaaagctg gaatttatga gcaagtatcc tatcttaaag aaggaagaag
    15661 tgtttatcta actcgttata atgaagttca aactgaaaca gcaactttaa tcttaggagc
    15721 tattgtgggg atagctagtt ccttattact attttattct gtcaatcttc tatatttcga
    15781 gcaattccgc cgagatatct tgattaaacg aatttcaggt ttacgatttt ttgaaacaca
    15841 tgctcagtat atggttagcc aatttgccag ttttgtattt ggtgctagtc tctttatttt
    15901 aagcagtcga gacttggtga ttggcttgct cactttattg gtctttctag ctagtgcagt
    15961 tttgacgctt taccgtcaag cgcagaaaga atctcgtgtt tctatgacaa ttatgaaagg
    16021 aaaataggat gattgaacta aagaatatat ctaaaaaatt tggaagccgt cagctatttt
    16081 cagatacgaa tcttcatttt gaaggtggga aaatttatgc cttaatcggt acaagtggct
    16141 gtggtaagac aacactcttg aatatgattg gacgattgga gccatatgac aaagggcaaa
    16201 tcatctatga tggcacttct cttaaggaca tcaagccttc tgttttcttt agagattact
    16261 taggatactt atttcaagat tttggcttaa ttgaaagcca aaccgtcaaa gagaatctca
    16321 atctgggttt agttggtaaa aagttgaagg aaaaagagaa aatctctttg atgaaacaag
    16381 ctctaaactg tgtaaacctc tcttatttgg atttgaagca acctatattt gagttatcag
    16441 gaggagaagc acaacgtgtt gcactagcga agataatttt aaaggatccg cctttgattc
    16501 ttgcagatga accaaccgct tccttagacc ccaaaaattc tgaggaatta ctttccatcc
    16561 tagaatcttt aaaaaatccg aatcggacca ttattattgc gacccacaat cctctgattt
    16621 gggagcaagt ggatcaggtc attcgagtta ccgatttatc acatagatga tatggtaaga
    16681 ttcagttaga agaaagagtc acaaacacac tttgtggctt ttttatttcc ataaaaatgg
    16741 taaaatagta ggagtagaaa tggagttcga gacatgaaag taatagatca atttaaaaat
    16801 aagaaagttc ttgttttagg tttggccaag tctggtgaat ctgcggctcg tttgttggac
    16861 aagttaggtg ccattgtgac agtaaatgat gggaaaccat tcgaggacaa tccagctgcc
    16921 caatgtttgc tggaagaagg gatcaaggtc attacaggtg gccatccttt ggaactcttg
    16981 gatgaagagt ttgccctcat ggtaaaaaat ccaggtatcc cctacagcaa tcccatgatt
    17041 gaaaaggctt tggccaaggg aattccagtc ttgactgagg tggaattggc ttatttgatt
    17101 tcagaagcac cgattattgg tatcacagga tcgaacggta agacaaccac aacgactatg
    17161 attggggaag ttttgactgc tgctgggcaa catggtcttt tatcagggaa tatcggctat
    17221 cctgccagtc aggttgctca aatagcatca gataaggaca cgcttgttat ggaactttct
    17281 tctttccaac tcatgggtgt tcaagaattc catccagaga ttgcggttat taccaacctc
    17341 atgccaactc atatcgatta tcatggatta tttgaggaat atgtagcagc caagtggaat
    17401 atccagaaca agatgacagc agctgatttc cttgtcttga actttaatca agacttggta
    17461 aaagacttgg cttccaagac agaagccact gttgtaccat tttcaacact tgaaaaggtt
    17521 gatggagctt atctggaaga tggtcaactc tacttccgtg gtgaagtagt catggcagcg
    17581 aatgaaatcg gtgttccagg tagccacaat gtggaaaatg cccttgcgac tattgctgta
    17641 gccaagcttc gtgatgtgga caatcaaacc atcaaggaaa ctctttcagc cttcggtggt
    17701 gtcaaacacc gtctccagtt tgtggatgac atcaagggtg ttaaattcta taacgacagt
    17761 aaatcaacta atatcttggc tactcaaaaa gccttatcag gatttgacaa cagcaaggtc
    17821 gtcttgattg caggtggttt ggaccgtggc aatgagtttg acgaattggt gccagacatt
    17881 actggactca agaagatggt catcctgggt caatctgcag aacgtgtcaa acgggcagca
    17941 gacaaggctg gtgtcgctta tgtggaggcg acagatattg cagatgcgac ccgcaaggcc
    18001 tatgagcttg cgactcaagg agatgtggtt cttcttagtc ctgccaatgc cagctgggat
    18061 atgtatgcta actttgaagt acgtggcgac ctctttatcg acacagtagc ggagttaaaa
    18121 gaataaaata tgaaaaaaat tgtctttaca ggtgggggga cggttggaca cgttaccctc
    18181 aatcttttgt taatgcccaa gttcatcgaa gatggttggg aagtccacta tatcggggac
    18241 aagcgtggta tcgaacacca agaaatcctt aagtcaggtt tggatgtcac tttccactcc
    18301 attgcgactg ggaaattgcg tcgctatttc tcttggcaaa atatgctgga cgtcttcaaa
    18361 gttggctggg gaatcgtcca atcgctcttt atcatgttgc gacttcgtcc acagaccctt
    18421 ttttcaaagg ggggctttgt ctcagtaccg cctgttatcg cagcgcgtgt gtcaggagtg
    18481 cctgtcttta ttcacgaatc tgacctgtct atgggcttgg ccaataaaat cgcctataaa
    18541 tttgcgacta agatgtattc aacctttgag caagcttcga gtttgtctaa ggttgagcat
    18601 gtgggagcag tgaccaaggt ttcagatcaa aaaaatccag aaccagatga attggtggat
    18661 attcaaaccc actttaatca taaattgccg actgtattgt ttgttggcgg ttctgcaggt
    18721 gctcgtgtct ttaaccaatt ggtgacagac cataagaaag aactaacaga gcgctacaat
    18781 attatcaatc taactggaga ttctagcctg aatgagttga gccaaaatct ttttcgtgtt
    18841 gactatgtga ccgatctcta tcaacccttg ttggaattgg ctgatattgt tgtgacacga
    18901 ggtggtgcca atacgatttt tgagctcttg gcgatagcaa aattgcatgt cattgtgccg
    18961 cttggtcgtg aagctagtcg tggtgaccag attgaaaatg cagcttactt tgtaaaaaaa
    19021 ggctatgcag aagaccttca agaaagcgat ttgaccttgg atagtttgga agagaagctt
    19081 tctcacttac taagtcacaa ggaagattac caagctaaga tgaaagcttc taaggaattg
    19141 aaatctctag cagattttta tcaattgttg aaaaaagatt tatcataagg aaagtaaatg
    19201 tcaaaagata agaaaaatga ggacaaagaa atcctcgaag aattgaaaga gttatcagaa
    19261 tggcagaaac gaaaccaaga atatctaaaa aagaaggctg aagaagaggc ggctctagct
    19321 gaggagaagg aaaaggaaag acaagctcga atgggagaag aatctgagaa gtcagaggat
    19381 aaacaggacc aggagagtga aacagaccag gaagattcag aatcagctaa ggaagagtct
    19441 gaagaaaaag tagcatcctc agaggctgac aaagagaaag aagagaaaga agaaccagag
    19501 tctaaagaga aggaggaaca ggataaaaag ctttctaaaa aggctacaaa ggaaaaacca
    19561 gccaaagcaa agattcctgg tatccatatc ttgcgagcct tcacgatttt atttccaagt
    19621 ctgcttttat tgattgtctc tgcctacttg ctcagtcctt atgcgaccat gaaagatatt
    19681 cgtgttgagg gaacggtgca aactacagct gatgatattc gacaggcttc aggcattcag
    19741 gattcggatt atacgattaa ccttctgcta gacaaggcaa aatatgaaaa gcagattaag
    19801 tctaactatt gggttgaatc agctcaactt gtctatcaat ttccaactaa gttcactatt
    19861 aaggtcaagg aatatgatat tgtagcctac tatatttctg gtgaaaatca ttatcctatt
    19921 ctttccagtg gtcagcttga gactagttct gtgagcctga acagtttacc agaaacttat
    19981 ttatcagttc tctttaatga tagtgaacaa atcaaggttt ttgtctcaga acttgctcaa
    20041 attagcccag aactcaaggc ggctatccaa aaggtggaat tagccccaag caaggtgaca
    20101 tccgatttaa ttcgattgac catgaatgat tcggacgaag tcttggttcc tctatctgaa
    20161 atgagtaaga aactgccata ttacagtaaa attaagcctc aattgtcaga accgagtgtg
    20221 attgacatgg aagctggaat ttacagttac actgtggcgg ataaattaat tatggaagct
    20281 gaggaaaaag ccaaacaaga ggccaaggaa gccgagaaaa aacaggaaga agaacagaaa
    20341 cgtttagaag aagaacagaa aaaacaagag gaagagagca atcgaaatca aacaaatcag
    20401 cgttcatcgc gtcgctaggt ttaccttttc tcttatagtt ctttagtgac catgttttta
    20461 cttgacaagt gctagtagaa ataatagaat agtaaaaaac ctttaaagca gtccagagag
    20521 gcagctaagg ttagacggtg aaagggtgga gactacccat ttttcgtgga accttgctgt
    20581 tggcaggttc cttttttcgt ggcttctgtt ggccagactc tctcactagt aaaggtaaaa
    20641 ggagaaacct atgcgagaac atcgtccaat cattgctctt gattttccta gttttgaggc
    20701 ggtcaaggaa tttttagctc ttttcccagc agaagaaagc ctttatctca aggtagggat
    20761 ggagctttat tacgcagcgg ggcctgagat tgtgtcctac ttaaaaggtt tgggtcatag
    20821 tgtctttttg gatctcaaac ttcatgacat tcctaataca gtcaagtcag ccatgaaggt
    20881 cttgtctcag cttggtgtcg atatgactaa tgtccatgcg gctggtggtg tagagatgat
    20941 gaaggcggcg cgtgaaggtc ttgggagtca agccaaattg atcgctgtaa ctcagctcac
    21001 atcaacgtca gaagctcaga tgcaggagtt tcaaaatatc caaaccagtc tgcaagagtc
    21061 tgtgattcac tatgccaaga agacagctga agctggcttg gatggtgttg tttgctcggc
    21121 tcaggaagta caagtcatca agcaggctac caatccagat tttatctgtc tgacaccagg
    21181 gattcgtcca gctggtgttg cagttggaga tcaaaaacga gtcatgacac ctgctgatgc
    21241 ctatcaaatc ggcagtgact atatcgtagt gggacgtccc attacccaag ctgaggatcc
    21301 tgttgcagct tatcatgcca tcaaggatga atggacacag gactggaatt aaagaactag
    21361 attagaaaaa taaaaggaga ataccatgac acttgctaaa gatatcgcta gccacctctt
    21421 gaaaatccaa gccgtttacc tcaaaccaga ggaacccttc acttgggcat ctggtatcaa
    21481 gtcaccgatt tacactgata atcgtgtgac actagcctat ccagaaactc gtaccctaat
    21541 tgaaaatggt tttgtggaag ctatcaaaga agcctttcct gaagtagaag tgattgcagg
    21601 aactgcaaca gcagggattc cacacggagc cattattgct gataagatgg acttgccttt
    21661 tgcctacatc cgtagcaaac caaaagacca cggagctggt aatcaaatcg aaggtcgcgt
    21721 agctcaaggt caaaaaatgg tagtggttga agaccttatt tcaacgggtg gttcagttct
    21781 tgaagctgta gcagcagcca agcgagaagg agcagatgta cttggagttg tagcgatttt
    21841 cagctaccaa ttgccaaaag cagataagaa ctttgcagat gctggtgtta aacttgtgac
    21901 gctttcaaac tatagcgagc ttatccatct agcccaagaa gaaggttaca tcacgccaga
    21961 gggccttgat cttctaaaac gctttaaaga agaccaagaa aattggcaag aaggttaggt
    22021 cagtaagata aagagagacg aggctaccga gtctctttta ccattttatt taaaatatga
    22081 caatatttta aataaaataa ttgacaacgc tttcttttat tgatataatg aaaatgtaat
    22141 atgtatcaaa ttgatcaatc aactatcttg tttatcactt cttaagagga cgatgtcatg
    22201 aaaagaagaa aaatatattc cttttttgcg tagttacaat tgcatctagt ttgtttctcc
    22261 ctacagtttt agctagacag attggaaatt atgatttaac gttgccgcgt tggggttcgg
    22321 atacaactag tgagcttgag aaagaaaacg cctctgctgg aattaataat agtgacagca
    22381 ctggtggcgg taaaaggtta aatacctcta ttcgtagcgc ctatagtggg tcagatatta
    22441 ccccggtata ttcattgggg tctggctcta ggattgtcat gtactataat ggaggtggtg
    22501 acaattatat tggttctggt actagattag ctatggcgcc acaatttgga aatcatgtaa
    22561 gaattcatac ttcaggttct tggagtccag attcttatta acttacttgt cagagtaagc
    22621 cttaaagatg gttgattgtg ggtgtagcat gaaaaaagaa tgctacaccc tatttttatt
    22681 ataaggagga gtaaggatgg aatttttcat ttgtaatctt gtacgagtcg ttcaatcacc
    22741 tcgattttat atgtctttat ttttgaccct tctttgcatg agtttaggaa atttccttgc
    22801 tttcaatggt atttataaaa ttgaaggttt attgattttt tttgccgctt cttctattcg
    22861 aggattttca ccgattagcc tagtagctgc acttatctgt acactgccct attctagtca
    22921 gataatagag gatgctgaga gtcattttct aacagcacaa ttgtgccgaa tttctaaaaa
    22981 gaagtatctg gctattgtag gtagtactgc aattatttct tcttttctag tcttttttct
    23041 cccctattta ttattattag gaattaatct tttagtgact ccttatcagg aaatttatat
    23101 tggagattat agtggtgcct taaaagaatt atttgattct aatcagttgc tctatagtct
    23161 tgtgacgact ctctggtatg gagtttgggg cgctgtgttc tctatttttg gactagctag
    23221 tgctttgcta gtgaagagaa aaataggagc tattttcatc ccagttgcct atatgatggt
    23281 tggtggtatt ttttgggcta ttttagggct atcttactta gaacctgtga caacattagc
    23341 tttgggatat cagaaagata tcagtctttc cttagttagt gggcatcttg cttttatttt
    23401 atttgttagt tgtttggttg tttatggtac attttttcta cattcagagg actatgtata
    23461 atgaaacaat ttgttcaatt ttacaaaaaa gattttttat cagtattggt ttattttata
    23521 ttactgctat cctgtgtttt atctagtaca gtatatttat tgcgctgtcg ccaatattca
    23581 atccatccaa atgtattaga atggatttta gttttacttc aagatatgac gactggagta
    23641 tattgctttc cgttcacata tatattgttc tttttttatt tgatgaataa ctattttaat
    23701 aggttggagt gtcgcattcg tctgaaatca attaagcact ttaccagttt tagtttcaaa
    23761 ttagcagctc ttagtacggg gatttggacg gcgactttat ttttattgat ttttctaatt
    23821 gcatttagta atggttttag cttctctttg gagataaagg aggttgattt tttaagagaa
    23881 ttttatggta taagtattgc aaacaatgct agtttcttta taggattttt tttctcttat
    23941 atagcatact atttcttttt atccttactt actattagca gtttttcttg gtttaaaaaa
    24001 tcaaacatga gcttagtatt tctgtttact tttttatttg tagaatcctt attctggatt
    24061 tatcagttga acaatgggat aattggatta ttgccaattt ttcagtatat ggtaaattcc
    24121 aatccgtatg cattgattta ttggcttaca ttactatcta tcataattcc attgactgta
    24181 ttttctgttc atagaaactg gaggagagtg taaaagttgg aaatgggaaa gttaagtagt
    24241 cacatgtgga gattgaatca gataatctat accaagtact tttggggtta tgttcttttt
    24301 tggatattga tttgtttagg attatggtat tggttagaag gaaatgatag acttgttata
    24361 gaaattttaa aagggcctaa tctgagtcaa aactcttttt tagtcttatc tatatggttg
    24421 cttcattggt ttattattca tacatttttt ctagcagttg tatatcgtag aagagcatcc
    24481 gatttctttc tggaagtgat tcgattttct tctattaagc tctggattag gtatcagatt
    24541 tggacctgtt ttctttatgg acttatttta atcatggtaa aagttctagt gattcaattt
    24601 atgttacagt taccaaactg ggatatagga gttttgttta tagttgattc tttgaatgct
    24661 tgtgtgctat ccttgctttg ctttatgtta tacgcactag gagcgaatgt acaaatgaac
    24721 tttgcttgcg ttagtttctt tttactcatg attgtgtttg gtggtctatt tgtaggaaat
    24781 cgaactaatt atctatttta tattttgaat cgagggaatg gagatatagg acgagattta
    24841 tttcttcagt tgctattttt agtctttctt tttaaaagca ttttctattt cactcgtcaa
    24901 aagaggaggt ttatagaatg aatgaaataa ttacattaaa aaatattgag ttgaaattaa
    24961 aaaaaacatg tgtttttcaa aaccttaact ttagttgtaa acagggggaa attataggaa
    25021 ttactggtgc gaatggctca gggaaaagtg tattgtttaa attaatagct ggtttatata
    25081 gtccgtctta tggagaagtg ttaatcaatg gggaaaatat tgttcctgag agaaaaattc
    25141 cagctaattt gggagctttg attgaagaac ctggttttat aaattattat agtggcttta
    25201 agaatttaca atatttggca agcatacgag gagtagttgg taatcaggaa atcaatgata
    25261 cactgaaaat agttggtcta tatgagcaaa aagaccagaa agttaaaact tattcgctag
    25321 gtatgaggaa aaagctaggg attgctcaag caattatgga gaatccctct attcttttac
    25381 tagatgaacc tatgaatgcc ttggataaat caagtgtaga aaatatgaga acattgttta
    25441 gaaagctctc tagtgaaaaa gggacaacaa ttttgattgc tagtcatagt gaagaggata
    25501 ttcgtatctt atgtgataaa gtatatgcaa tagaagataa agtatgtaca ctgtgttcag
    25561 attgaacatc ttagatagac tcaggatgtt ataggtaaaa tcttaaaaag ggattggagc
    25621 ttaaaatcca gtccctttta agagttaatg gccaccttca acaaccaggt catctgcttt
    25681 agcagcgtca ccgtaggttg ggtgaagtgt tttttcatag gccttgtgga agaagttttc
    25741 cttgcctaat ttttcaatat ctttattgat gaagtctagc aattcttggt tgcctttttg
    25801 aactgctgcc gcaatggtat cgggatcacc gagggaagta attcctactt caaatccttt
    25861 attttcaagc gcccaagcta gaacttccgt attgtcagtt gaaaaggcat ctccacgtcc
    25921 gtcaagaaga gcttggtaag agtcactgta ttggtcgtat ttttggagtt tgatttctgg
    25981 atgattcttt tcaaaataag tctcagcagt cgttcctttt gtgacaatta aggttttacc
    26041 ttcaagttgt ttgacgtctg taatgagacc agtcttaggt gatacgacac ccagagaaac
    26101 tttcatatat ggaagggcaa aatcaacttg tttcttacgt tcgtcagtta ctgtaaagtt
    26161 agcaagagta atatctacct tgtttgaaat caagtattcc gcacggttgg cagcatcgac
    26221 tgaaatgtat ttaaccttga caccaaggtc ttgagctagt tggttcccta gttcaatatc
    26281 gtagcgtagc cttggtaaga accatcattg tcaacgtagc caaacggttt tttatctcca
    26341 aacacggcga ttcgcagttc accgcttttt ttgatttcat cgatagtgcg agctttggca
    26401 gttgtttttc cagaggatga accagcgttt ccacctgagc tacaagcagt gataaagata
    26461 agggcaaagg caagtgctaa aacagttaag agtggtttga atagtttcat aagaatctcc
    26521 tttatagata tgagccgaat tggctaaagt caaagacgtt taaaaattcc tgggctcgtt
    26581 tggtttgcgg attggtaaag aaggcttgag ctgttccttc ttcagcgatt ttcccttggt
    26641 cgaggaagat aatccggtca gcaatggctt gggcaaactg catttcgtgg gttactaaaa
    26701 tcatggtacg gccttcttgg gccaaatcat tgataagttc cagcacctca cgcaccattt
    26761 ctggatccag cgaagcagtc acctcgtcaa aaaggatgat ttctggatgc attaggaggg
    26821 cacggacaat tgcaacacgt tgcttctgtc caccagataa ttgacgggca aagctatgtt
    26881 gtttatccag caaaccgaca cgatctagta attgcaaagc ttcttccgtt acttctttct
    26941 tgtcccttcc ttgagttttg atagggccta ggatgaggtt ttgtaagaca tccagatggg
    27001 gaaagagttc ataactttga aagaccatgc caatcttttg gcgaactagg tgaaaatctt
    27061 ttttattttc aacgatagac tgaccatcca gaagaatatc tccaccttga atactttcta
    27121 agccgttgag gcaacgaagg agggtacttt tcccacaacc agatggccct aggatgacaa
    27181 caacttccct tttttgattt ctagagaaag tccttggagg atgggattgt ctccgaagga
    27241 tttttttagt tccttgattt ctaagatagt ttcagacatt tagtttctcc aatgtttttc
    27301 taagtgagtg gatagtttgg aaatagggta gcaaactgcg aaatataaga ctagaatggt
    27361 tccataaatc caaaatgaag cagttgggat ggtcaggcga ttgctatcga tgatttgttg
    27421 tccaactttg gtcacttcca caaccccaat caaaacaact aatgaagtgg ttttaatcat
    27481 ccgagtgaca agattgatag cctgcggtag cagtcttctt aagacttgtg ggatgatgat
    27541 gtggtagtaa agttgaacat tagtcaagcc gagtgcctgt ccactttcaa actgatgttt
    27601 agggagagaa gtgatagctc cacgtaccaa gtctcccatt tcagctgttc cccagagggt
    27661 aaaaacgata atagctgaag tctcacctga gatattgata ttaaagtttc gagctaagcc
    27721 aaagtaaacg atgaagagta gcaccagctg gggcatgata cgggtaaagt ccagatacaa
    27781 tcgtgttaaa aatcgtatga ttctagaatg ggaggtcatg atgattccca tgactgttcc
    27841 gaacatcatg gataagagga cagacaggat ggatatctca atcgtaacgc ccaatccctg
    27901 taagattctc aggagattat ttccctgaaa gagtacttgg attcccgaat cctgcatggc
    27961 ggagcctcct ttctatccag ctaaagacca gtgagatggg tagcagcatg atcagataag
    28021 caactaccaa catagctagc gcaatgtctg tctcatagta gagaccaatc aaatccttgg
    28081 cgacatacat gaggtcggcc aaagccactg ctgagaaaac agaggtttcc ttgataagga
    28141 aaatgacatt ggcactaaag gaggggagtg ccaccgctgt tgcttgcgga agaaccacat
    28201 agcgaaagac ctgtagaggt gtcagaccaa tagcgaggcc aatctcctgc tgggtttgac
    28261 tgatggcttc cagcccactt cggaaagatt ctgccatata ggatcctcct aaaaagacaa
    28321 gcccaagcgt tgcacagact tctgaagata ggacaatccc gattcgggga agaccgaagt
    28381 agagaaagaa gagttgaatc aaaaggggcg tattacgtga caattcaatg taggctgtcg
    28441 ctacttgcgc caaaacaggg attcgataat gtcggatgat actaacgatt aaaccgagca
    28501 gaaaggatcc caaaattccc caaactgcaa tatgcaaggt cagaaagaat gccttttgat
    28561 atagtggtag atattgttca acaatggacc aatccaaaaa tagaacctcc catctagaaa
    28621 taatacagtt attgtagcac ttaaaatctt ctttggataa tatctatttt ttattgccgt
    28681 tataaggatt ttttaccata gacataaaat ttctgaaatt tccaaacaaa atatttgaaa
    28741 agttttgaaa aaaagttaag atatttttgt aatatacaaa gtaaacgctt acttattaag
    28801 gaggacagtt tatgtcatac aaaacaagca atgcagaagg tcatgtagat ttcatcaata
    28861 cctatgattt ggagacaatg gcgcaacaag ttattcctaa agcagcattt ggctatatcg
    28921 ctagtggggc gggagatact ttcacttctt tccagtgatt ttagcgtcag gttcttttta
    28981 gtttttaaag attatccgtg aatttcttgc ttatttatga taaaatggga gtatcgcaaa
    29041 aaatgactca tcgtattcaa ttttgagtaa aactaggagg atcccatgtc tacagaacat
    29101 atggaagaac taaatgacca gcagatcgtt cgccgtgaaa aaatggctgc gctccgcgaa
    29161 caaggaatcg atcctttcgg aaaacgtttt gaacgtactg caaattcaca agaattaaaa
    29221 gataaatatg ccaacctcga taaagaacaa ttacacgata aaaacgaaac agctactatc
    29281 gcaggacgct tggtaaccaa acgtggtaaa ggaaaagttg gttttgccca ccttcaagac
    29341 cgcgaaggcc agattcagat ctacgttcgt aaggatgctg tcggtgaaga aaactacgaa
    29401 atcttcaaaa aagcagacct tggtgacttc cttggtgtcg aaggtgaagt gatgcgtacg
    29461 gatatgggag aactctctat caaggcaacc cacatcacac acttgtctaa ggctcttcgt
    29521 cctcttcctg agaaattcca tggtttgaca gacgttgaaa caatttaccg taaacgttac
    29581 cttgacttga tttctaaccg tgaaagcttt gaacgctttg tcactcgttc aaaaatcatc
    29641 tctgaaatcc gtcgttacct tgaccaaaaa ggattccttg aagtggaaac acctgttctt
    29701 cataatgaag ccggtggtgc tgctgcccgt ccatttatca cccaccacaa tgcccaaaac
    29761 attgacatgg tgcttcgtat cgcgactgag cttcacttaa aacgccttat cgtgggtggt
    29821 atggaacgtg tctatgaaat tggccgtatc ttccgtaacg aaggaatgga cgctactcat
    29881 aaccctgagt ttacttctat cgaagtttac caagcttatg cagacttcca agacatcatg
    29941 gacttgacgg aaggcattat ccaacacgct gctaaatcag ttaagggcga tggcccagtc
    30001 aactaccaag gtactgaaat caagattaac gaaccattta agcgtgttca tatggtggat
    30061 gctatcagag aaattactgg tgtcgatttc tggcaagaca tgactttaga agaagctaaa
    30121 gctatcgctg ctgagaagaa agttccagtt gagaaacact acactgaggt tggtcacatc
    30181 atcaatgcct tctttgaaga gtttgttgaa gaaactttaa tccaaccaac ctttgtctat
    30241 ggacatccag tagctgtatc tccactcgct aagaaaaatc ctgaagacca acgctttact
    30301 gaccgtttcg agctctttat catgactaag gagtacggta atgcctttac tgagttgaac
    30361 gacccaatcg accaacttag ccgttttgaa gcccaagcta aagctaaaga acttggtgat
    30421 gatgaagcga caggcatcga ctatgactac atcgaggctc ttgaatacgg tatgccacca
    30481 acaggtggtt tgggaatcgg tatcgaccgt ctctgcatgc tcctcactga tacaacaact
    30541 atccgtgatg tattgctctt cccaacaatg aaataaattc
//
LOCUS       DAVMJI010000026        29988 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.026, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000026 DAVMJI010000000
VERSION     DAVMJI010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29988
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.026"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            100..1575
                     /locus_tag="VYR58_001416"
     CDS             100..1575
                     /locus_tag="VYR58_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV3622553.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1925..8626
                     /locus_tag="VYR58_001417"
     CDS             1925..8626
                     /locus_tag="VYR58_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV3622554.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(8874..9730)
                     /locus_tag="VYR58_001418"
                     /pseudo
     CDS             complement(8874..9730)
                     /locus_tag="VYR58_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9941..10300)
                     /locus_tag="VYR58_001419"
     CDS             complement(9941..10300)
                     /locus_tag="VYR58_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV3622555.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            10392..11348
                     /locus_tag="VYR58_001420"
                     /pseudo
     CDS             10392..11348
                     /locus_tag="VYR58_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11332..11889
                     /locus_tag="VYR58_001421"
     CDS             11332..11889
                     /locus_tag="VYR58_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV3622556.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            11882..12136
                     /locus_tag="VYR58_001422"
     CDS             11882..12136
                     /locus_tag="VYR58_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622557.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12148..14202
                     /locus_tag="VYR58_001423"
     CDS             12148..14202
                     /locus_tag="VYR58_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV3622558.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14381..15241
                     /locus_tag="VYR58_001424"
     CDS             14381..15241
                     /locus_tag="VYR58_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV3622559.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLRDPVFKKD"
     gene            15452..16162
                     /gene="ccdA2"
                     /locus_tag="VYR58_001425"
     CDS             15452..16162
                     /gene="ccdA2"
                     /locus_tag="VYR58_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV3622560.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16182..16748
                     /locus_tag="VYR58_001426"
     CDS             16182..16748
                     /locus_tag="VYR58_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV3622561.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16759..17871
                     /gene="msrB"
                     /locus_tag="VYR58_001427"
     CDS             16759..17871
                     /gene="msrB"
                     /locus_tag="VYR58_001427"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV3622562.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISEDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            18184..18921
                     /locus_tag="VYR58_001428"
     CDS             18184..18921
                     /locus_tag="VYR58_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3622563.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            18918..20609
                     /locus_tag="VYR58_001429"
     CDS             18918..20609
                     /locus_tag="VYR58_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV3622564.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            20725..21288
                     /locus_tag="VYR58_001430"
     CDS             20725..21288
                     /locus_tag="VYR58_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV3622565.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            21310..26979
                     /locus_tag="VYR58_001431"
     CDS             21310..26979
                     /locus_tag="VYR58_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV3622566.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSETAS
                     LKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQ
                     INEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVNTN
                     ESKQSDVNEAAEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQIK
                     SITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDETE
                     SISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSSTSK
                     DAVLAVSSIEEEIIENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDIYY
                     DFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIF
                     DLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEGYL
                     EGRDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNADI
                     EVHRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVWPY
                     GAIDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTRIS
                     EEEANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNLTK
                     FTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGS
                     QKRYKVTSTGKFSITNLPEYQVEDLNVMYTSEHIVHPLDSSLINNLVEELKKVELYTE
                     STYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSGAV
                     AALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRL
                     GSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDY
                     IQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFVSR
                     EKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIPGS
                     EWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSE
                     YGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNMAF
                     ERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKWFK
                     KVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADFET
                     SYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQASRD
                     EGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTFEE
                     LQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            27040..28761
                     /gene="pabB"
                     /locus_tag="VYR58_001432"
     CDS             27040..28761
                     /gene="pabB"
                     /locus_tag="VYR58_001432"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV3622567.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFHSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAYPFDPEILRQKIEAECQTCDANQDYRLRISLSKSGEIEFSRQIL
                     TPLSPSFCQAKLCLQEANLNQSFTYFKTTYRPHLSIEEQEKIYHNGKGELLETSIGNL
                     VLKIDGKLYTPPIRLGILPGIYHQYLLETGQVEEKVLTLADFAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            28881..>29988
                     /locus_tag="VYR58_001433"
     CDS             28881..>29988
                     /locus_tag="VYR58_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV3622568.1"
                     /translation="MKSKIVLGASLAIATLSLVSLVEIEGLSPFLIENVSANTHSANK
                     VINHKVSIYLENADEGKGLTVNFSTDSVSPNLFDEFEKKSGITITTMLVNAKTGEVVE
                     KRLTPSVFLRSNDLTSGTISSFIFSEYPDGEYKYVVSKGDFIDPKTQFKHQYRGESPV
                     FRIRNRKYVELGTTDKKLDERRDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSV
                     NSNLLNSFGEKAKKVLIRSKLINVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDL
                     TDGEYKYVAYESQQYTDPQTTLTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPK
                     PDEKPKPSAPQQEKTKPTVQSGWVGSSYYQNGKKV"
BASE COUNT         9422 a         5407 c         6576 g         8583 t
ORIGIN      
        1 tccagtattt gacaatattg aagcagctat taaagaacat ggattaagct aattctaatt
       61 tgttaacatt catataacat aaaaaaggga ggaactgtta tggatgcaat ctttgaccta
      121 atcggaaagg ttttcaatcc catcttagaa atgggtggac ctgtcatcat gttgatcatt
      181 ttgacagtat tggctttact ttttggagtg aaattctcca aagcgcttga aggtggtatc
      241 aaacttgcca tcgctcttac aggtatcggt gctatcatcg gtatgctaaa tggtgctttc
      301 tcagcatcac ttgcaaaatt cgttgaaaac actggtatcc aattgagtat tacagacgtt
      361 ggttgggcac cactcgcaac aatcacttgg ggttctgctt ggacactata cttcttgctc
      421 atcatgttga ttgtcaacgt agtgatgctt gctatgaaga aaaccgatac acttgatgtc
      481 gatatctttg atatctggca cttgtctatc acaggtctct tgattaaatg gtatgctgat
      541 aacaatggtg tgagtcaagg ggtttcactc tttattgcta cagcagctat cgtccttgtc
      601 ggtgtgttga aaattatcaa ctctgacttg atgaaaccta catttgatga ccttcttaac
      661 gccccaagtt catcaccaat gacatcaact cacatgaact acatgatgaa cccagttatc
      721 atggttttgg ataagatttt tgaaaaattc ttcccaggcc ttgataaata tgactttgat
      781 gctgctaaat tgaacaagaa aatcggtttc tggggatcta aattcttcat cggtttcatc
      841 cttggtatcg ttatcggtat tatgggaact ccacatccaa ttgcaggtgt tgcagatgca
      901 gataaatggc gtcttgttat caaaggatgg ttgtctcttg gtttgactgc cggtgtatct
      961 ttggaactct tctcacttat cggttcatgg ttcatcgcag ccgtagaacc actatcacaa
     1021 ggtattacaa acgttgctac taaacgtctt cgaggacgta aattcaatat cggtcttgac
     1081 tggccattca tcgctggtcg tgctgaaatc tgggcttgtg ccaacgtact tgcaccaatc
     1141 atgttgattg aagcagtgct tctttcaaaa gttggaaatg gtatcttgcc acttgcaggt
     1201 atcatcgcta tgggtgttac tccagctctc ttggttgtaa ctcgtggtaa attgctccgt
     1261 atgattatct tcggaacact cttgttgcca ctcttccttc tttcaggtac acttattgca
     1321 ccatttgcaa cagaacttgc taaaggtgta ggtgccttcc cagaaggtgt gagccaaact
     1381 caattgatta ctcactctac tcttgaagga ccaatcgaaa aacttcttgg ttggacaatt
     1441 ggtaacacta caactggtga tatcaaagca atccttggtg cagtagtctt ccttgtattc
     1501 tatatcggta tctttgcttg gtacagaaaa caaatgatca aacgtaacga agagtacgca
     1561 gcaaaagcaa aataatgcgc tcctataaaa tataaactca atgaaaatca aagagcaaac
     1621 taggaaacta gccgcaggtt gctaaaaaca cagttttgag gttgtagata agactgacga
     1681 agtcagctca aaacatggtt ttgaggttgt agatgaaact gacgaagtca gctcaaaaca
     1741 tggttttgag gttgtagatg aaactgacga agtcagtaat catatctacg gcaaggcgac
     1801 gctgacgaag tttgaattgg attttcgcag agtgtaaatt gttgaaacta ggttgtcata
     1861 ccatgtatac cacttgggct ttggtagtag ctaactgcac taaatataat ataaggaggg
     1921 ttttatgggg aaaggccatt ggaatcggaa aagagtttat agcattcgta agtttgctgt
     1981 gggagcttgc tcagtaatga ttgggacttg tgcagttcta ttaggaggaa atatagctgg
     2041 agaatctgta gtttatgcgg atgaaacact tattactcat actgctgaga aacctaaaga
     2101 ggaaaaaatg atagtagaag aaaaggctga taaagctttg gaaactaaaa atgtagttga
     2161 aaggacagaa caaagtgaac ctagttcaac tgaggctatt gcatctgaga agaaagaaga
     2221 tgaagccgta actccaaaag aggaaaaagt gtctgctaaa ccggaagaaa aagctccaag
     2281 gatagaatca caagcttcaa gtcaagaaaa accgctcaag gaagatgcta aagctgtaac
     2341 aaatgaagaa atgaatcaaa tgattgaaga caggaaagtg gattttaatc aaaattggca
     2401 ctttaaactc aatgcaaatt ctaaggaagc cattaaacct gatgcagacg tatctacgtg
     2461 gaaaaaatta gatttaccgt atgactggag tatctttaac aatttcgatc atgaatctcc
     2521 tgcacaaaat gaaggtggac aactcaacgg tggggaagct tggtatcgca agactttcaa
     2581 actagatgaa aaagacctca agaaaaatgt tcgccttact tttgatggcg tctacatgga
     2641 ttctcaagtt tatgtcaatg gtcagttagt ggggcattat ccaaatggtt ataaccagtt
     2701 ctcatatgat atcaccaaat accttcacaa agatggtcgt gagaatgtga ttgctgtcca
     2761 tgcagtcaac aaacagccaa gtagccgttg gtattcagga agtggtatct atcgtgatgt
     2821 gactttacaa gtgacagata aggtgcatgt tgagaaaaat gggacaacta ttttaacacc
     2881 aaaacttgaa gaacaacaac atggcaaggt tgaaactcat gtgaccagca aaatcgtcaa
     2941 tacggacgac aaagaccatg aacttgtagc cgaatatcaa atcgttgaac gaggtggtca
     3001 tgctgtaaca ggcttagttc gtacagcgag tcgtacctta aaagcacatg aatcaacaag
     3061 cctagatgcg attttagaag ttgaaagacc aaaactctgg accgttttaa atgacaaacc
     3121 tgccttgtac gaattgatta cgcgtgttta ccgtgacggt caattggttg atgctaagaa
     3181 ggatttgttt ggttaccgtt actatcactg gactccaaat gaaggtttct ctttgaatgg
     3241 tgaacgtatt aaattccatg gagtatcctt gcaccacgac catggggcgc ttggagcaga
     3301 agaaaactat aaagcagaat atcgccgtct caaacaaatg aaggagatgg gagttaactc
     3361 tatccgtaca acccacaacc ctgctagtga gcaaaccttg caaatcgcag cagaactagg
     3421 tttactcgtt caggaagagg cctttgatac gtggtatggt ggcaagaaac cttatgacta
     3481 tggacgtttc tttgaaaaag atgccactca cccagaagct cgaaaaggtg aaaaatggtc
     3541 tgattttgac ctacgtacca tggtcgaaag aggcaaaaac aaccctgcta tcttcatgtg
     3601 gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc cactctttag caactgttaa
     3661 acgtttggtc aaggttatca aggatgttga taagactcgc tatgttacca tgggagcaga
     3721 taaattccgt ttcggcaatg gtagcggagg gcatgagaaa attgctgatg aactcgatgc
     3781 tgttggattt aactattctg aagataatta caaagccctt agagctaagc atccaaaatg
     3841 gttgatttac ggttcagaaa catcatcagc aacccgtaca cgaggaagtt actatcgccc
     3901 tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat tatgaacagt cagattatgg
     3961 aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca tggacttttg accgtgacaa
     4021 cgctggctat gctggacagt ttatctggac aggtacggac tatattggtg aacctacacc
     4081 atggcacaac caaaatcaaa ctcctgttaa gagctcttac tttggtatcg tagatacagc
     4141 cggcattcca aaacatgact tctatctcta ccaaagccaa tgggtttctg ttaagaagaa
     4201 accgatggta caccttcttc ctcactggaa ctgggaaaac aaagaattag catccaaagt
     4261 agctgactca gaaggtaaga ttccagttcg tgcttattcg aatgcttcta gtgtagaatt
     4321 gttcttgaat ggaaaatctc ttggtcttaa gactttcaat aaaaaacaaa ccagcgatgg
     4381 gcggacttac caagaaggtg caaatgctaa tgaactttat cttgaatgga aagttgccta
     4441 tcaaccaggt accttggaag caattgctcg tgatgaatct ggcaaggaaa ttgctcgaga
     4501 taagattacg actgctggta agccagcggc agttcgtctt attaaggaag accatgcgat
     4561 tgcagcagat ggaaaagact tgacttacat ctactatgaa attgttgaca gccaggggaa
     4621 tgtggttcca actgctaata atctggttcg cttccaattg catggccaag gtcaactggt
     4681 cggtgtagat aacggagaac aagccagccg tgaacgctat aaggcgcaag cagatggttc
     4741 ttggattcgt aaagcattta atggtaaagg tgttgccatt gtcaaatcaa ctgaacaagc
     4801 agggaaattc acccttactg ctcactctga tctcttgaaa tctagtcaag tcactgtctt
     4861 tactggtaag aaagaaggac aagaaaagac tgttttgggg acagaggtgc caaaagtaca
     4921 gaccattatt ggagaggcac ctgaaatgcc taccactgtt ccgtttctat acagtgatgg
     4981 tagtcgtgca gaacgtcctg taacctggtc ttcagtagat gtgagcaagc ctggtattgt
     5041 aacggtgaaa ggtatggctg acggacgaga agtagaagct cgtgtagaag tgattgctct
     5101 taaatcagag ctaccagttg tgaaacgtat tgctccaaat actgacttga attctgtaga
     5161 caaatctgtt tcctatgttt tgactgatgg aagtgtacaa gagtacgaag tagatagctg
     5221 ggagattacg gaagtagata aagccaaact ttcagtagct ggatcacgta ttcaaatgac
     5281 tggtcagtta gctggagaaa ctattcatgc aacccttgtg gtagaagaag gaaatgctgc
     5341 agcacctgta gtgccaactg ttactgttgg aggtgaagca gtaacaggtc ttactagtcg
     5401 acaaccaatg caatatcgta ctctatctta tggtgcccaa ttgccagaag tcacagcaag
     5461 tgctgaaaat gctgatgtga cagttcttca agcaagcgca gcaaacggca tgcgtgcaag
     5521 catatttgtt cagcctaaag atggtggccc tcttcaaacc tatgcaattc aattcctaga
     5581 agaagcacca aaaattgctc acttgagctt gcaagtggaa aaagctgaca gtctcaaaga
     5641 agaccaaact gtcaaattgt cggttcgagc tcactatcaa gatggaacgc aagctgtatt
     5701 accagctgat aaagtaacct tctctacaag tggtgaaggg gaagtcgcaa ttcgtaaagg
     5761 aatgcttgag ttgcataagc caggagcagt cactctcaaa gcggaatatg agggagctaa
     5821 aggccaagtt gaactcacta tccaagccaa tactgagaag aagattgcgc aatctatccg
     5881 tcctgtaaat gtagtcacag atttgcatca aaaacctact cttccaacaa cagtaacggt
     5941 tgagtatgac aaaggtttcc ctaaagctca caaagtcact tggcaagcta ttccgaaaga
     6001 aaaactagac tcctatcaaa catttgaagt actaggtaaa gttgaaggaa ttgaccttga
     6061 agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt gaagaagtca gtgtgacaac
     6121 tccaatcgca gaagcaccac aattaccaga aagtgttcgg acatatgatt caaatggtca
     6181 cgtttcatca gctaaggttg catgggatgc gattcgtcca gagcaatacg ctaaggaagg
     6241 tgtctttaca gttaatggtc gcttagaagg tactcaatta acaactaaac ttcatgttcg
     6301 cgtatctgct caaactgagc aaggtgcaaa catttctgac caatggaccg gttcagaatt
     6361 gccacttgcc tttgcttcag actcaaatcc aagcgaccca gtttcaaatg ttaatgacaa
     6421 gctcatttcc tacaataacc aaccagccaa tcgttggaca aactggaatc gtactaatcc
     6481 agaagcttca gtcggtgtcc tattcggaga ttcaggtatt ttgagcaaac gttcagttga
     6541 taacttaagc gttggcttcc atgaagacca tggagttggt gcaccgaagt cttatgtgat
     6601 tgagtattat gttggtaaga ctgtcccaac agctcctaaa aaccctagtt ttgttggtaa
     6661 tgaggaccat gtctttaatg attctgccaa ctggaaacca gttactaatc taaaagcccc
     6721 tgctcaactc aaggctggag aaatgaacca ctttagcttt gataaagttg aaacctatgc
     6781 tgttcgtatt cgcatggtga gagcagacaa caaactagga acgtctatca cagaggtaca
     6841 aatctttgcg aaacaagttg cggcagccaa gcaaggacaa acaagaatcc aagttgacgg
     6901 taaagactta gcaaacttca accctgattt gacagactac taccttgagt ctgtagatgg
     6961 aaaagttacg gcagtcacag caagtgttag caacaatggc ctcgctaccg tcgttccaag
     7021 cgttcgtgaa ggtgagccgg ttcgtgtcat cgcgaaagct gaaaatggcg acatcttagg
     7081 agaataccgt ctgcacttca ctaaggataa gaacttactt tctcataaac cagttgctgc
     7141 ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt gaattgccga ctaaggttcc
     7201 agtttacttc acaggtaaag acggctacga aacaaaaaac ctgacagttg aatgggaaga
     7261 agttccagcg gaaaatctga taaaagcagg tcaatttacc gttcgaggcc atgtccttgg
     7321 tagtgatctt gttgctgagg tcactgtacg agtgacagac aaactaggcg aagctctttc
     7381 agataaccct aactatgatg aaaacagtaa ccaggccttt gcttcagcaa ccaatgatat
     7441 tgacaaaaac tctcatgacc gcgttgacta tctcaatgac ggagatcatt cagaaaatcg
     7501 tcgttggaca aactggtctc caacaccatc ttctaatcca gaagtatcag cgggtgtgat
     7561 cttccgtgaa aatggtaaga ttgtagaacg gactgttgct caagccaaac ttcacttctt
     7621 tgcagatagt ggtacggatg caccaactaa actcgtttta gaacgctatg tcggtccaga
     7681 gtttgaagtg ccaacctact attcaaacta ccaagcctac gacgcagacc atccattcaa
     7741 caatccagaa aattgggaag ctgtgcctta tcgtgcggat aaagacatcg cagctggtga
     7801 tgaaatcaac gtaacattta aagctgtcaa agccaaagct atgagatggc gtatggagcg
     7861 taaagcagat aagagcggtg ttgcgatgat tgagatgacc ttccttgcac caagtgaatt
     7921 gcctcaagaa agcacgcaat cgaagattct tgtagatgga aaagaacttg ctgatttcgc
     7981 tgaaaatcgt caagactatc aaattaccta taaaggtcaa cggccaaaag tctcagttga
     8041 agaaaacaat caagtagctt caactgtggt agatagtgga gaagatagcc ttccagtact
     8101 tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa taccgtatcc agttgactaa
     8161 ggaaaaacca gtttctgaga agacagttgc tgctgtacaa gaagatcttc caaaactcga
     8221 atttgttgaa aaagatttgg cctacaagac agttgagaaa aaagattcaa cactgtatct
     8281 aggtgaaact cgtgtagaac aagaaggaaa aactggtaaa gaacgtatct ttacagcgat
     8341 taatcctgat ggaagtaagg aagaaaaact ccgtgaagtg gtagaagctc cgacagaccg
     8401 catcgtcttg gttggaacca aaccagtagc tcaagaagct aaaaaaccac aagtgtcaga
     8461 aaaagcagat acaaaaccaa ttgattcaag tgaagctagt caaactaata aagcccagtt
     8521 accaaataca ggtagtgcgg caagccaagc agcagtagca gcaggtttag ctcttctagg
     8581 tttgagtgca ggattagtag ttactaaagg taaaaaagaa gactagaaat tttgatacct
     8641 tctttatcat taaagaccaa agaaaaactc ttgtcctaaa tagaagataa agagtctgga
     8701 acaaaatagt tctcaaccac aaaaaagcta gatatttcca attgcggaac tctagctttt
     8761 taattttgag tcgttctctt attgtatagt agattgaaac tagagtagta cacttctact
     8821 tctaaaacat tgttagaaat cgatttgact gtccttatcg atttgtcctg ttcttatttc
     8881 atttcactat gttttaggag gttattggcc ataagtacca atcccatgtc aattctcact
     8941 tgacgcttgc ctctcagatt acatctcttg taacccaaac aagcctttat ctgcccaaag
     9001 acaggttcta catcaatctt gcgttgagcg aaaatctgtc tatcttgggg agataaaagc
     9061 gcctgacatt ctttagcttt caagttttga tagcgttcgt tcatatacaa tcccttttga
     9121 ggggctgatt caggttcatc agcgtagtaa accttgattt cctgttgaaa gtctgtctgt
     9181 gttttctggt acttgatatg gtgaaaacga tagcaccagc catcaggatg tatgtagcta
     9241 tcctccttgt cattatagtg ccaattcgct aagtttttag ctgactgttt ataccctctc
     9301 ttttgttcct tatcaaacat ggcatattta atcagaaggg gagtgatttc ttcttgaaaa
     9361 tagacttgta tctgttcttg aagtttggcg gagaatttct ctgtcgtttt cttccacaca
     9421 aaactatact tgttggcatt ggattcaatc ttagttccgt caataaacaa acaatctaag
     9481 gtcactaact cttccatttt tcaatttttc gaccagagaa aatcccttgt gaataggcaa
     9541 atagaagagt agatacaagc attttagggt gataagacgg gcgaccaaag gcatgatagg
     9601 aggtgtagaa gtgacgttcc tccaaggtat tcaccacttt ttcaatagta aagacgagat
     9661 ggtcttgtgg taagaaggaa ctgatttcta gtggtaaagt tgtttgattt gtgttatagt
     9721 gaatatgcat gggatagcct ttctaaatgg tttattaagc aattctattt taccaagact
     9781 atcgtaacca tgcaaaaaag caacggcaaa tccgttgcct tttttggata taagagacta
     9841 ttgtcccaga ctcttttctt tgtataaaat tgtatagtgt tattgtctat actattttgt
     9901 agagaaagca aaaatcccta gaaaatgctt agggattcga ctatttcatt aagaacaatt
     9961 caacaatcat ctctatatac atgataaggg ttaataaaaa tcctgtacgc cagaagaatt
    10021 tgatgaattt aggatagtaa aagctgcgtt tttttaaaag gaagaaaaag acgagaataa
    10081 tggctaggaa cgagagggct agccccagtc tagggaggaa attatgggta aaggttttag
    10141 ctgtaatcaa gtaatactca aataccaaga ctggaaaagc caaatccgca aagtttcgtc
    10201 ctagtttttt taatctaaaa agtttggtta ggataatgca gacgactaag gtcagtatca
    10261 ataataaaat agatgctaat ttcattaaaa tcatacccat attgtatcat aaaaaaaggc
    10321 taatggaaac gagaaacaga ggaatttata ggaaagtcag gcttttgaga ttgtgggtga
    10381 tttttgttat aatgaaagtt ataaaatctt atgatacctt gaatgattat tatcgaaaac
    10441 tctttggaga aaagactttt aaagtcccta ttgatgcggg atttgactgt cccaatcgtg
    10501 atggaactgt ggctcatgga ggctgtactt tttgtacggt ttccggttct ggagatgcca
    10561 ttgtagcccc agatccgcct atccgtgagc aattttataa ggaaattgac tttattcatc
    10621 gtaagtggcc agatgttcag aagtatctgg tttattttca aaattttacc aacacccatg
    10681 aaaaggtgga agttattcga gagcgttatg aacaggctat caatgagcca ggtgtggtag
    10741 gaatcaatat tggaacgcgc ccagactgtt taccagacga aaccatcgaa tatttggctg
    10801 agttatcgga gtgcatgcat gtgacggttg aattgggctt gcagactact tatgaagcaa
    10861 cctctgacct gattaaccgt gcgcattctt atgaattgta ggtggaaacg gtcaagcgtt
    10921 tgagaaagta tccaaaaatt gagattgttt cccatttgat caatggtttg cctggtgaaa
    10981 cccatgagat gatggttgaa aatgtccgcc gttgtgtcac ggataacgat attcaaggga
    11041 ttaaactgca tttgctccat cttatgacaa atactcgtat gcaacgagat taccatgagg
    11101 gacgtttaca attgatgagt caggacgaat atgtcagggt catctgtgac caactggaaa
    11161 ttattcccaa acatatcgtc atccatcgaa ttacaggaga tgcgcctagg gatatgctga
    11221 ttggtcctat gtggagcctc aataaatggg aagtcctcaa cagcattgag atggagatga
    11281 gacgtcgtgg aagtgttcaa ggatgcaagg ctgtaaaaca ggagtttgaa aatgaaaaga
    11341 ccacttgaga tggcacatga ttttttggct gaggtcgtga caaaagagga tgtcgtagtg
    11401 gatgcgacta tgggaaatgg tcatgacacg ctttttttag ccaagctagc caagcaagtc
    11461 tatgcctttg atattcagaa gcaagccttg gaaaagaccc aagagcgttt gcatcaggct
    11521 ggcttgacaa atgcccagtt aatcttgcaa ggccatgaga cactggacca gtttgtgaca
    11581 aaagctaagg cagggatttt taatttgggc tatttgccgt cagctgataa gtctgtcatc
    11641 acccgaccgc agacaacgat tgaggcatta gaaaagctat gtggcttact tgtcaaaggt
    11701 ggacgaattg ctattatgat ttactatggt catgaaggag gcgacctcga gagagatgct
    11761 gtcttggatt ttgtgatcca gttgaaccaa caagagtaca cagctgccat ttaccgaact
    11821 ttaaaccaag tcaacaaccc gccgttttta gtgatgattg aaaaattaga gagatacaga
    11881 catggataaa caatacctac acgaaaagct ggatgccatg cgccagaatt ttgttgaatc
    11941 aacctaccac gaacgagcgg tgggcgtgct agaccaagcg catatgagca aaaaaatgct
    12001 taaaatcaag aaaaaattag ttgctcttga aatggaacgg tgccagagaa aaattgagca
    12061 caaagactgt tccaagattg accaaaaaat caaagagcag aaggagatat ttgaatcctg
    12121 ttgtaaaaaa gattaaggag gacgtgcgtg gaattactga tttacctcat cctattttta
    12181 ctggtcttga ttgtctcaag tacaaccaat aagctcctac cctttttgcc tctccctttg
    12241 gtgcagattc ttttgggaat tgtgattggt ctctttttac ccaatactga ctttcacctt
    12301 aatacggagt tgtttttggc actggttatc ggccccttgc ttttccgaga ggctgaagaa
    12361 gcagatgtta cggctatttt aaaacactgg cgaatcattg tttatctcat atttccagtg
    12421 atttttatct cgaccctgag tttgggtggc ttggcccatc ttctttggtt cagccttccc
    12481 ttggcagctt gcttggctgt tggggcagcc cttggtccta cggacttggt ggcctttgcc
    12541 tctctttcgg agcgttttag ctttcctaag cgcgtgtcca atattcttaa gggcgaagga
    12601 ctcttgaatg atgcttctgg tttggtggct tttcaggtag ctttgacagc ttggacaact
    12661 ggagcttttt ctctggggca agctagcagt tcactcatct tttcaatcct aggcggtttt
    12721 ttaattggat ttttaacagc catgaccaac cgcttcctcc ataccttctt gctaagtgtg
    12781 cgtgcaacgg atattgccag tgaactttta ttagaattga gtttgcctct tgtgaccttc
    12841 tttctggcag aagaagttca tgtttcaggt attattgccg tcgtagttgc tggaatttta
    12901 aaggcaagtc gtttcaagaa aatcacgctc ctcgaagccc aagtggatac ggtgaccgag
    12961 acggtctggc atacagtgac ctttatgctc aacggttctg tctttgtgat tttagggatg
    13021 gagctggaaa tgatagcaga acctatcttg accaatccaa tctataatcc tctactttta
    13081 ttgctatctc ttatcgccct tacctttgtc ctctttgtca ttcgttttat tatgatctat
    13141 ggctattatg cctatagaac ccgacgcctc aagaaaaagc taaataagta tatgaaggac
    13201 atgtttctct tgaccttttc aggtgttaag ggaacggtgt cgattgctac gattctcttg
    13261 ataccaagta atctagaaca ggagtatcct ctcttgcttt tccttgttgc aggtgtgacg
    13321 cttgttagct ttttaacagg tctcttggtc ttgcctcatc tttctgatga agaggaagaa
    13381 agcaaggatt atctcatgca tatcgccatt ttgaatgaag taacgctaga gttggaaaaa
    13441 gagttggaag acaccagaaa taaactttcc ctctatgcgg ctattgacaa ttatcatgga
    13501 cgtattgaaa atctcatttt aagccaagaa aaccaggatg atcaagaaga ctgggctgct
    13561 ttgaaactct tgattcttag tattgaaagt gatggtttgg aacaggccta tgaagagggg
    13621 aatattagca atcgtgctta ccgagtttac caacgttatc tgaaaaatat agaacaagga
    13681 atcaatcgta aacttgcctc aagactgacc tattattttc ttgtttcctt gaggatttta
    13741 cgttttctcc ttcatgaagt ttttactctt ggaaagacct tccgtagctg gaaggacaag
    13801 gagcaaagcc gtctccgtgc tcttgattat gaccaaattg cagagctcta tcttgccaat
    13861 acagagatga ttattgaaag tttggaaaac ctgaagggag tctacagacg ctctttgatt
    13921 agttttatgc aggagtctcg tcttcgagaa acagctatta tcagcagtgg tgcctttgtc
    13981 gaacgggtta tcaatcgtgt caaacccaac aatatcgatg aaatgctgag aggctattat
    14041 ctggagcgca agttgatttt cgaatacgaa gaaaaacgat taattacaac taagtatgcc
    14101 aagaaattac gacaaaatgt aaataactta gagaactatt ccttgaagga agctgccaat
    14161 accctgccgt atgatatggt ggaattggta agaagaaatt agttaatact cttcgaaaat
    14221 ctcttcaaac cacgtcagcg tcgccttgga ttatatatgt gactgacttc gtcagtttca
    14281 tctacaacct caaagcaggg ctttgagcaa cctgcggcta gcttcctagt ttgctctttg
    14341 attttcattg agtataagat tataaatgaa ggagtatgac atgaaaaagt ggtggaaaga
    14401 gctgatagac aagcctttat taaaagcttt tttgcattat tatcaagcat cagatagtga
    14461 gttgaccagt gtcgcagtag cctactattg gttgatttcg attttccccc tgcttttggt
    14521 ggtggtcaat atcctcccct attttcagat tcctgtggga gaatttctgt gctttatgaa
    14581 agacgttctg cccccaagcc tctatgaagg tgtggaaaaa atagccagag aagttttgac
    14641 gcaaccttca acaggtttat tgagtttttc tgttttatcg gcgttatgga gtttttcaaa
    14701 atctatgaat ttcttgcaaa aagcttttaa caaggcttat ggcgtcgaaa agagtcgtgg
    14761 acttatttcc catcagatgc taagtctcct agtcagtttt ggcttgcagc tcctctttgc
    14821 gtttgccttg tttttgatct tatttggtca gatgattttg gctttacttg ctcattattg
    14881 gacaaaagat ggcattatct atcaggcttt acaagggttg gcaggtcctc tgatttacgc
    14941 cctcctcttt gctatcttgg tcatgcttta ttattttctt cccaatatat ctaacaggaa
    15001 aattagctat accctaccag gcagtgcctt tgttctctta gtgattttag gtttactaac
    15061 tctgttctct agttatctca attactatgt ccatcatttg gtggatgtcc gaattttagg
    15121 ttccgttctt cttgttgtta tgatgttttg gtttatcttg attgctaaaa ttgttatcct
    15181 aggcgcggtt atcaatgcca gtatgcagag tttgagagat ccggtcttta aaaaagacta
    15241 actatttatc cattacaaaa gcgcatagta tcaaaacttt atagaacctt gatactatgc
    15301 gcttttgtgc tttgacagtt ttttgtatag tttttgtcca agatttctaa atcatctgat
    15361 taaattccta ttttccccta tcattgtccc tgttttttcg aaaatggaag gagtataata
    15421 aatctatcaa taaaatgata ggaggaactt tatgggtcat attttctttt ttctaagtgt
    15481 ctttttggca gggattctat ccttcttttc tccttgtatc ttacctttgt taccggtcta
    15541 tacaggagtg ttactagatg ataaggatgg tgctcaggct tctagcggca aattttcaat
    15601 ctcagttact agtttattac gaactctggc ctttatagca ggaatttcct ttatatttat
    15661 tttgttgggc tatggagctg gttttttagg cgatttgctt tatgcttctt ggttccaata
    15721 tcttactggg gcaattatta tccttcttgg tttgcaccaa atggagattc tacactttaa
    15781 ggggctttat aaggaaaaga ggctacaact gcaaggacag gggcaaaatg gtaagggcta
    15841 tagtcaggca tttttattgg gcttgacctt tagttttgct tggacgcctt gcgtggggcc
    15901 ggttctgggg tctgttttgg ccttggcggc ttcaggtggt tcaggagctt ggcagggagc
    15961 tggtctcatg ttggtgtata cgctgggctt ggcgctacca ttcttgcttc tagctctgac
    16021 ctctagttat gttttgaaac atttccgaaa acttcatccc tatctcggaa tcctcaaaaa
    16081 agtgggtggt tttctcatta ttgtgatggg actcttggtt ctgtttggaa atgcttcaat
    16141 tttaagtcaa ttatttgaat aaaatggaaa ggaatatcaa tatgaaaaaa tggcaaacat
    16201 gtgttcttgg agcaggttcg ctcctttgtt tgacggcttg ttcaggcaag tccgtgacta
    16261 gtgaacacca aacgaaagat gaaatgaaga cggagcagac agctagtaaa acaagcgcag
    16321 ctaaagggaa agaggtggct gattttgaat tgatgggagt agatggcaag acctaccgtt
    16381 tatctgatta caagggcaag aaagtctatc tcaaattctg ggcttcttgg tgttccatct
    16441 gtctggctag tcttccagat acggatgaga ttgctaaaga agctggtgat gactatgtgg
    16501 tcttgacagt agtgtcacca ggacataagg gagagcaatc tgaagcggac tttaagaatt
    16561 ggtataaggg attggattat aaaaatctcc cagtcctagt tgacccatca ggcaaacttt
    16621 tggaaactta tggtgtccgt tcttacccaa cccaagcctt tatagacaaa gaaggcaagc
    16681 tggtcaaaac acatccagga ttcatggaaa aagatgcaat tttgcaaact ttgaaggaat
    16741 tagcctagga ggtgtcttat gaatgataag ttaaaaatct tcttgttgct aggagtattt
    16801 tttctagcca taaccggttt ctatgttcta ttgatacgaa atgcagggca gacagatgcc
    16861 tcgcaaattg aaaaggcggc agttagccaa ggaggaaaag cagtgaaaaa aacagaaatt
    16921 agtgaagacg cagacttgca cgaaatttat ctagctggag gttgtttctg gggagtggag
    16981 gaatatttct cacgcgttcc cggggtgacg gatgccgttt caggctatgc aaatggtaga
    17041 ggagaaacaa ccaagtacga attaattaac caaacaggtc atgcagaaac cgtccatgtc
    17101 acctatgatg ccaagcaaat ttctctcaag gaaatcctgc ttcactattt ccgcattatc
    17161 aatccaacca gcaaaaataa acaaggaaat gatgtgggga cccagtaccg tactggtgtt
    17221 tattacacag atgacaagga tttggaagtg attaaccaag tctttgatga ggtggctaag
    17281 aaatacgatc aacctctagc agttgaaaag gaaaacttga agaattttgt ggtggctgag
    17341 gattaccatc aagactatct caagaaaaat ccaaatggct actgccatat caatgttaat
    17401 caggcggcct atcctgtcat tgatgccagc aaatatccaa aaccaagtga tgaggaattg
    17461 aaaaagaccc tgtcacctga ggagtatgca gttacccagg aaaatcaaac agaacgagct
    17521 ttctcaaacc gttactggga taaatttgaa tccggtatct atgtggatat agcaactggg
    17581 gaacctctct tttcatcaaa agacaaattt gagtctggtt gtggctggcc tagttttacc
    17641 caacccatca gtccagatgt tgtcacctac aaggaagata agtcctacaa tatgacgcgt
    17701 atggaagtgc ggagccgagt aggagattct caccttgggc atgtctttac ggatggtcca
    17761 caggacaagg gcggcttacg ttactgtatc aatagcctct ctatccgctt tattcccaaa
    17821 gaccaaatgg aagaaaaagg ctacgcttat ttactagatt atgttgatta atactcttcg
    17881 aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg tagggttact gacttcgtca
    17941 gttttatcta caacctcaaa gctatacttt gagctgactt cgtcagtttt atctacaacc
    18001 tcaaagctat actttgagct gacttcgtca gttttatcta caacctcaaa gcggtacttt
    18061 gagaaacctg tggctatctt cctagtttac tttttgattt ttattgagta taagaggtct
    18121 ttcctaagca gttagaggag aattttgcta tactgatact agtaagtggt aaaggagcag
    18181 agcatgacct acacaatctt aatcgtagaa gatgaatatc tggtaagaca aggtttgact
    18241 aaactggtca atgtagcagc ctacgatatg gaaatcatcg gtcaggctga aaatggaagg
    18301 caggcttggg aattgatcca aaagcaggtg ccagatatca ttttaaccga tatcaacatg
    18361 cctcatctaa atggcatcca gttggccagt ctggtacgag aaacctatcc tcaggttcat
    18421 ttggtctttt taacaggtta cgatgatttt gattatgcct tgtctgctgt caaactaggt
    18481 gtggacgact acctgctcaa acccttttct cgtcaggata ttgaggaaat gttggggaaa
    18541 atcaaacaaa aactagacaa ggaagagaaa gaagagcagt tacaagattt attgactaat
    18601 aggtttgaag gaaacatggc ccagaaaatc cagtctcatc tggctgatag ccaatttagt
    18661 ttaaagtctt tagccagtga cttaggtttt agtccgacct atctgagttc cttgattaag
    18721 aaagagttgg gcttgccttt tcaggattat ctggtgagag aacgtgttaa acaagccaag
    18781 ctcttgcttt taactacaga tctgaagatt tatgagatcg cagagaaggt tggttttgaa
    18841 gatatgaact attttaccca acgttttaag cagattgcag gtgtgacacc tcgtcagttt
    18901 aagaagggag aagaccgatg aagcgttctt ctcttttagt tagaatggtt atttccatct
    18961 ttctggtctt tctcattctc ctagctctgg ttggaacttt ctactatcaa tcaagttctt
    19021 cagccattga ggccaccatt gagggcaaca gccaaacgac catcagccag actagccact
    19081 ttattcagtc ttatatcaaa aaactagaaa ccacctcgac tggtttgacc cagcagacgg
    19141 atgttctggc ctatgctgag aatcccagtc aagacaaggt cgagggaatc cgagatttgt
    19201 ttttgaccat cttgaagtca gataaggact tgaaaactgt tgtgctggtg accaaatctg
    19261 gtcaggtcat ttctacagat gacagtgtgc agatgaaaac ttcctctgat atgatggctg
    19321 aggattggta ccaaaaggcc attcatcagg gagctatgcc tgttttgact ccagctcgta
    19381 aatcagatag tcagtgggtc atttctgtca ctcaagaact tgttgatgca aagggagcca
    19441 atcttggtgt gcttcgtttg gatatttctt atgaaactct ggaagcctat ctcaatcaac
    19501 tccagttggg gcagcagggc tttgccttca ttatcaatga aaaccatgaa tttgtctacc
    19561 atcctcaaca cacagtttat agttcgtcta gcaaaatgga ggctatgaaa ccctacatcg
    19621 atacaggtca gggttatact cctggtcaca aatcctacgt cagtcaagag aagattgcag
    19681 gaactgattg gacggtgctt ggcgtgtcat cattggaaaa gttagaccag gttcggagtc
    19741 agctcttgtg gaccttgctt ggggccagtg tcacatctct tcttgtctgt ctctgcttag
    19801 tgtggttcag tcttaaacgc tggattgctc ctttgaagga tttgagagaa accatgttgg
    19861 aaattgcttc tggtgctcaa aatcttcgtg ccaaggaagt tggtgcctat gaactgagag
    19921 aagtaactcg ccaatttaat gctatgttgg atcagattga tcagttgatg gtagctattc
    19981 gtagccagga agaaacgacc cgtcagtacc aacttcaagc cctttcgagc cagattaatc
    20041 cacatttcct ctataacact ttggacacca tcatctggat ggctgaattt catgatagtc
    20101 agcgagtggt gcaggtgacc aagtccttgg caacctattt ccgcttggcg ctcaatcaag
    20161 gcaaggactt gatttgtctc tctgacgaaa tcaatcatgt ccgccagtat ctctttatcc
    20221 agaaacaacg ctatggagat aagctggaat acgaaattaa tgaaaatgtt gcctttgata
    20281 atttagtctt acccaagctg gtcctacaac cccttgtaga aaatgctctt taccatggca
    20341 ttaaggaaaa ggaaggtcag ggccatatta aactttctgt ccagaaacag gattcgggat
    20401 tggtcatccg tattgaggat gatggcgttg gcttccaaga tgctggtgat agtagtcaaa
    20461 gtcaactcaa acgtggggga gttggtcttc aaaatgtcga tcaacggctc aaacttcatt
    20521 ttggagccaa ttaccatatg aagattgatt ctagacccca aaaagggacg aaagttgaaa
    20581 tatatataaa tagaatagaa actagctaac tcccagtcaa ttctgggagt tttatgcgta
    20641 attgggcaaa ctttctaggt tgtctatctt gctaaaaaca agaaaaaacg gtatgataga
    20701 agagtgacaa cagaggtaac agagatgaac gagacacaga ttcaaagaga aacacgtcag
    20761 gtagtggaag atgttttaga aaagaccaat ttgaagcagg gggccctttt tgttttaggt
    20821 ctatcttcta gtgaggtgct aggtggtcat attgggaaag aatccagtca agagattggt
    20881 gagctgatag tggagactat cttggatatt ctaggtagta gaggtatcca tttagcagtt
    20941 caaggttgtg agcatgtcaa tcgggctctc gttgttgaac gtcaggtggc agagcagttt
    21001 ggtctggaaa ttgtcagtgt ccatcctact cttcatgcag gaggttcggg gcagttggca
    21061 gcctttaagt ttatgcagga tccagttgag gttgaattta tcaaggctca tgctggattg
    21121 gatatcggag acactgcaat tggcatgcat gtcaagcatg ttcaggttcc gattcgccct
    21181 attttgagag agattggtca tgcccatgta acggcactgg ctagtcgtcc aaaattaatc
    21241 ggaggtgcgc gtgcgcacta tccgcaagat gctattagaa agacctgaga atgaataaag
    21301 gagataaaag tgtttaaaaa agaccgtttt tcaattcgta agattaaggg agttgtaggc
    21361 tctgtatttc ttggaagcct tttgatggct ccttctgtag tggacgcagc cacctatcac
    21421 tatgtaaata aagagattat ttcacaagaa gctaaagatt taattcagac aggaaagcct
    21481 gacaggaatg aagttgtata tggtttggtg tatcaaaaag atcagttgcc tcaaacaggg
    21541 acagaagcat ctgttttgac agcttttggt tatctatcag gtgacatcct caaaacgctt
    21601 ggcttggaca ctgttttaga agaaacctca gcaaaacctg gagaggtgac tgtagtcgaa
    21661 gttgagactc ctcaatcaac aacaaatcag gagcaagcta ggacagaaaa ccaagtagta
    21721 gagacagagg aagctccaaa agaagaagca cctaaaacag aagaaagtcc aaaggaagaa
    21781 ccaaaatcgg agataaaacc tactgacgac acccttccta aagtagaaga ggggaaagaa
    21841 gattcagcag aaccagctcc agttgaagaa gtaggtggag aagttgagtc aaaaccagag
    21901 gaaaaagtag cagttaagcc agaaagtcaa ccatcagaca aaccaacaga ggaaccaaaa
    21961 gttgaacaag taggtgaacc agtcgagcca agtgaagacg aacaggcacc aacggcacca
    22021 gttgagccag aaaagcaacc agaagctcct gaagaagaga aggctgtaga ggaaacaccg
    22081 aaaccagaag ataaaataaa gggtattggt actaaagaac cagttgataa aagtgagtta
    22141 aataatcaaa ttgataaagc tagttcagtt tctcctactg attattctac agcaagttac
    22201 aatgatcttg gacctgtttt agaaactgca aaaggtgtct atgcttcaga gcctgtaaaa
    22261 cagcctgagg taaatagtga gacaaataaa cttaaaacgg ctattgacgc tctaaacgtt
    22321 gataaaactg aattaaacaa tacgattgca gatgcaaaaa caaaggtaaa agaacattac
    22381 agtgatagaa gttggcaaaa cctccaaact ggggttacag aagctgaaaa agttgcagct
    22441 aatacagatg ctaaacaaag tgaagtaaat tctgagactg caagtcttaa aacagcaatt
    22501 tctagattaa atacagataa agttgaactc gaaaatcaac ttaagattgc acagggaaaa
    22561 actgaaactg atttcagcat ggaatcttgg actgttttga gtacagctaa aaataaagct
    22621 caggaagtaa aagataacgg aacagcgacc caagaacaaa taaacgaagc agagaaaagt
    22681 ttgaaaacag cccttgctga cttatctgtt gacaaaacag ctttgggaag cgctatcgat
    22741 acagctacta agaaaaataa agagaattat acaaatcaaa catgggcaga gttggaaaca
    22801 gcgcttacag cagcaaaatc tgtaaatact aacgagtcta aacaaagcga cgttaacgaa
    22861 gctgctgaaa aattaactgc aactatggaa aaattggttg aattgtctga aaagccacgt
    22921 ttgactctat ctattgaaaa gagagacata gatcgaaaag ctacggtcac gtatactttg
    22981 gaaaatccag caaatactca aataaaatca ataactgcaa ctctgaaaaa aggagaggaa
    23041 gttgttaagg attttgtttt aacagaagaa aatcttaaaa ctaatcattt aactgctttg
    23101 tttgaaaagc tagactacta caaagaatac actctatcta cggatatggt atataacaga
    23161 ggaaatgatg atgagacgga gagtatttca gaagaactaa ttcagctgaa tcttaagaaa
    23221 ctagaattga aagatatcca gacagtctct ctgatgaaat ttgaaaatgg tcaagaaagt
    23281 caggttacac acttgtctga taaaccgacc gatttgagta aattatactt aaaagttaca
    23341 tcatcaacgt ctaaggatgc tgtgttagcc gttagctcta tagaagaaga gattattgaa
    23401 aataaaaaaa tctttaaaat tcatgcagat acaccagaat tagtagttcg taagaaagat
    23461 ggcagtcttt ctaagggatt tgactattac atggagagag ttatccctca tgatggtgat
    23521 atttattatg attttaaaga cttgatttca gctatgacat ctaatcctac aggtacgttt
    23581 attttaggga gagatatttc ctcgcgtaat gtaaaaccgg atggaaatgg aaaatcttat
    23641 atcaaaggtg aatttaaagg aaaactactt ggtacaaatg ataatgttag acactcgatc
    23701 tttgacttag aatatccatt gtttgatact ataaaatcag gagtcgtgaa agatattgat
    23761 ttcaagcatg tcaatatggt attcccagat agcaatcaag gagataacgt agcaacaatt
    23821 gcaagagtaa tcaaagataa gacaaaaatt gagaatgtta atgttgaagg ttatctcgag
    23881 ggtcgagatc atgtagctgg tttagttaat aatcttgaag gtaattccga aattgaaaat
    23941 gtatccttta caggaaagat taagtctaaa ggtggtaatt ctattacagc aggtattgca
    24001 ggtagaaata tcttatctcg tgttaaacgt gcctatgtaa atgcagatat agaggtacat
    24061 cgatcatcta attctagcat gcttgttgca gtaaatggaa taaacgcaga tgcaagtggt
    24121 ggttggggaa cctggggtag acttactgag tcagttgcta aaggaacatt agaaaccaag
    24181 caaggagggc aagctggagg agcctcttct acagtctggc cttatggagc aattgataat
    24241 gttgtcagct atgcaaaagt gaccaaaggg aaagaattat ttggatcaga tggtgattta
    24301 aattatgatt ggtttatgaa aaaaattagt aatatttttg gtgttcaagg catcagctca
    24361 ggcgattcgg gtagtgattc taaatttacg cgtatttctg aggaagaagc aaatcaaaaa
    24421 gttgcttctt ataatattac agctcccaac ttgatgagtg actcaagtct tttggtagac
    24481 agactcaatg aaagttggaa aaatactgat caatttgaaa gtatacagga ttatcaagcc
    24541 caaaaccaat taatttacca gaacttgact aaatttactc cttattacaa taaagaattt
    24601 attgttcatg aaggaaatgc tctcactcct gaacaggaaa tattgaagac taagaaaatc
    24661 aaatcgattg tagggttgaa aggaacagag ttcgttgtag atggcagtga tattgatact
    24721 atcatgcttc attttgagga tggtagtcag aagcgatata aggtaacctc tactggtaag
    24781 ttttcgataa ctaatttacc ggaatatcag gttgaagatt taaatgtgat gtatacatca
    24841 gaacatatag tacatccact agattcgtca ctgataaata accttgttga agaattgaaa
    24901 aaagtagaat tgtatacaga gtctacttac caagttctag gtattgataa agataatgct
    24961 aacaaattga atagaactaa gagattattc ttagatgagt cattagatgc tgttaaaaca
    25021 caattgccta cctttgtaaa aacaatgttt gaaaatgagt ggttgcacat caatggagaa
    25081 tctagtggag ctgtcgctgc tttacgacaa aaaatcatgg ataataagac ggctatattg
    25141 cttgctttga cttatatcaa tcgttattat gatgttaaat tctcagacta taatattaaa
    25201 aaactgatgc tctttaaacc aactttccat ggtgaaaaga ttgatctatt agatcgatta
    25261 atccgactag gatcatctgg agaaaataga ttaaaaggtt cagaaaatgc agaaacgttc
    25321 aagcagttat ttgctagcga aacgaagcag aaggatttgg tgacttattt agactacaat
    25381 cgctctttgt tgactaatta tcaaacaaca ggggaatggt ttaaagaaac gactaaggat
    25441 tatattcaat ttgaggaacg tccatcctta gtagaggaga ttaaagatgc caaatatcga
    25501 gtttacgata atttaaccgc accgtattat caaggatata tcctacctct cttaacgttg
    25561 aagaatactc atttagcaat tttatcgaac tatagtacta tgacatttgt cagccgtgaa
    25621 aaacgcccta attggaaaaa tgaagatttt gataagtggg tgaaatatgt agcaactgct
    25681 catagaaacc atgttgatac ttggtataag attttacctg ataatatcaa aggtaaaatg
    25741 gttaaagaga atgttactgc tgtttgggaa ggattgagca tcccaggaag tgaatgggta
    25801 gaccagaatg ctgtagatag aaaaggaaga gattacgccc cagctcgaga attctttaat
    25861 cttgtaggtg gtcctatggg aggttggtat gcttaccatg gttatggtgc gcatgctgga
    25921 ggaagaaatc gggttaatta tgaggtgttt gatgtattaa gtgagtatgg tatatcggtc
    25981 tttactcatg aattgactca cgttaatgat acttggattt acttaggagg gtatggtaga
    26041 cgtgaaaata tgggacctga agcttatgct cagggattat tccagtctcc tgttccaggt
    26101 cagccgggtt ggggggcgct tggtctcaat atggcatttg aaagaaaaaa tgatggtgat
    26161 ctaatttata atgcctcccc aactcaattt gaaaatagga aagagttaga tagttatatg
    26221 aaaaattata acgatactct catgatggtg gactacttgg aaggagatgc agttatctct
    26281 aaaggtaaag aagctattac taaatggttt aaaaaagttg aacctaaggt tgttagtcaa
    26341 acagctcagt atgatacggt tcgtcagttg actgctgaag agaaagaaaa actttctgtt
    26401 tctagtgttg atgatttagt tgatcaagga ttaatgtcag acagagctgt aggaaataat
    26461 acctataatc cagctgattt tgaaacaagt tatattgcga tagattatat gactggtatt
    26521 tatggtggag gaaagaatag tgtaggttca ccaggtgcct tgatgtttaa acataatact
    26581 ttccgtatgt ggggctacta tggttttgaa gaaggtgttc taggatatgc ttctaataaa
    26641 tttaagcaag catctagaga tgaaggtcat gctggactta gtgataactt tattatttct
    26701 aagatttcca aaggggaatt tttaactatg gaagcattta aaaagggata ttttaagaaa
    26761 gtagtagaag agttaaaaac taaaggtatt cgtcctgtta ctatcaatca aaaaacatat
    26821 agcacctttg aagaattgca agaaggattt aagcaggctg ttgaaagaga tttgaagaaa
    26881 aatcagttag atgagaggga aacaagaaac ttcaaattcc aagttttcag acaacttctt
    26941 caacaaacag atagctttaa aacttctatc tttagataat cgaaatctct catctgcttt
    27001 gcggatgagg gttttcttat tttatgctat acttaaagta tgcatagaaa aacagtgatt
    27061 gattttagga ctttggggga gagatatacc tttacccagc ctattaaaga gttgaaaacg
    27121 agaaatgtag aagaagtggc agatttgctg gcacaagtgg aaagctacca agagcaaggt
    27181 tattatgtgg tggggtatgt cagctacgag gctgcacctg cttttgagga aaaattagca
    27241 gttcacaagg atcccctact gggagagtac ctgctttatt ttactgttca tgatagcgta
    27301 gaaacttccc ctattcctct gacttatgag gatattgatt tgccctcaaa ttggcaggaa
    27361 gtaacgtctg cagcagacta tgaaaaggcc attgcccaaa ttcaccatca tttacggcag
    27421 ggagatacct atcaggtcaa ctacaccgtc caacttaagc aaaagttaaa tgccaatcct
    27481 tttgccatct acaatcgtat ggtggtagag caggaggcgg gctacaatgc ctatgtggaa
    27541 catgacgaga tggcagtgat ttccatgagc ccagagctct tttttgagca aaatgatcgc
    27601 gagttgacaa cacgaccaat gaaggggacg actcagcgtg gggtaactga ccaagaagat
    27661 cttgaacagg ccagttggtt ggaacaggat cccaaaaatc gctctgaaaa tatgatgatt
    27721 gtggacctct tgcgcaatga tatgaaccgt atttctgaag ttgggagcga gcacgtggag
    27781 cgtctgtgtc aggtagagca gtattcaact gtttggcaga tgacttcgac catcaagagt
    27841 cagttgcgag aggatgtgga ccttgttgaa atcttccact cactctttcc ttgtggttcc
    27901 ataacgggtg caccgaaaat tgcgacaatg gagattatca aggacttgga gcctcaaccg
    27961 cgtggagtct actgtggaac gattggtctc ttgcttccaa atggacgacg gatttttaat
    28021 gtggccattc gtaccattca acttcacaaa ggtcaagcca tttatggagt tggcggaggg
    28081 attacttggg atagcacttg ggaatctgaa taccgtgaag ttcatcaaaa ggcagcagtt
    28141 ctctatcgta aacaagctcg cttccaatta attacaactg gaaaaatcag ccaaaaacaa
    28201 ctgatgtttg aagaacaaca tctggaaagg ctgagaaaag ctagtcggta ttttgcttat
    28261 ccttttgacc cagaaatttt gagacaaaag attgaagcag agtgtcagac ttgtgatgct
    28321 aatcaagatt accgcttgcg aatttctctc agcaagtctg gagagataga attcagtcgt
    28381 caaatcttaa cacctcttag tccaagtttt tgtcaggcca aactttgtct gcaagaagcg
    28441 aatttgaatc aatcctttac ctattttaaa acgacttaca gaccgcattt gagcatagag
    28501 gaacaagaga agatttacca taatggaaaa ggagaacttc ttgaaacctc tatcggaaat
    28561 ttggttctga aaatcgatgg gaaactctac acaccgccta tccgacttgg aatcttgcca
    28621 ggaatttatc accagtattt actagaaaca ggacaggtag aagagaaagt cttgaccttg
    28681 gcagattttg cccaagcaga agctatttac ggctgtaatg cagtgagagg cttgtatgag
    28741 ttgcaagtga taggattgtg agttttagct attaatagtt tttaatatat attaaaatat
    28801 attggtgttt acttttgatg agatatcata tttgtgttat aatgtaaccg taaacaatag
    28861 aaatttaaag gagatttttg atgaaatcaa aaatagtttt gggagcttcg ctagcgatcg
    28921 caacacttag cttagtatct cttgtcgaga ttgaaggact ctcaccgttt ttaatagaga
    28981 atgttagcgc aaatactcat tctgcaaata aagttattaa tcataaagta agtatttact
    29041 tagaaaatgc tgatgaaggt aaaggtctaa ctgtaaactt ttcaacagac agtgttagtc
    29101 caaatttatt tgatgagttc gaaaaaaaga gtggaattac aataactact atgttagtga
    29161 atgctaagac aggtgaagtt gtagaaaaaa gattaacacc aagcgttttt ttacgttcca
    29221 atgatttaac cagtgggacc atatcttcgt ttatttttag tgaatatcct gatggagaat
    29281 ataaatatgt tgtgtctaaa ggagacttta tcgatcctaa gactcagttt aaacatcagt
    29341 atagaggaga atctccagtt tttagaatac gtaatcgaaa atatgtggag ttgggaacaa
    29401 ctgataaaaa attagatgaa agacgtgata atagcgttta taaagatggg gttgttgaac
    29461 acaaggtaaa tttaagttta acaagttatc aaggaggtaa tggagttact gcaatttttt
    29521 caactgatag tgttaactct aacttactta attcttttgg tgaaaaggct aaaaaagttt
    29581 tgattaggtc taagttaatt aatgttaaga ctggcgaggt tattgatgaa acgttttctc
    29641 caaaagtaag tttaacctct aaaattttga aaagtggttc tacagcagta ttttatttta
    29701 tagatttaac tgatggcgaa tataaatatg ttgcgtatga aagccagcaa tatactgatc
    29761 ctcaaacaac attgactcat cagtatagag gagaatctcc tatttttagt atcaaagatg
    29821 gaaaattttc tggtttagta tctgcctcaa aaccagacga aaacccgaag ccaacgccaa
    29881 aaccggatga gaaaccaaaa ccttcagcac cacaacagga gaaaacaaaa cctacagttc
    29941 agtctggttg ggtaggttca tcttattatc aaaatggtaa aaaagtca
//
LOCUS       DAVMJI010000027        27486 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.027, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000027 DAVMJI010000000
VERSION     DAVMJI010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27486
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.027"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(134..457)
                     /gene="tnpB"
                     /locus_tag="VYR58_001434"
     CDS             complement(134..457)
                     /gene="tnpB"
                     /locus_tag="VYR58_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV3622569.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
     gene            complement(718..1017)
                     /locus_tag="VYR58_001435"
     CDS             complement(718..1017)
                     /locus_tag="VYR58_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV3622570.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1182..1589)
                     /locus_tag="VYR58_001436"
     CDS             complement(1182..1589)
                     /locus_tag="VYR58_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV3622571.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATPFKEVQKPLENFN
                     HIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            1715..2561
                     /locus_tag="VYR58_001437"
                     /pseudo
     CDS             1715..2561
                     /locus_tag="VYR58_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(2768..5026)
                     /locus_tag="VYR58_001438"
     CDS             complement(2768..5026)
                     /locus_tag="VYR58_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV3622572.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(5255..5485)
                     /locus_tag="VYR58_001439"
     CDS             complement(5255..5485)
                     /locus_tag="VYR58_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV3622573.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            5675..6358
                     /locus_tag="VYR58_001440"
     CDS             5675..6358
                     /locus_tag="VYR58_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV3622574.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRLKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            6358..7092
                     /locus_tag="VYR58_001441"
     CDS             6358..7092
                     /locus_tag="VYR58_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV3622575.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            7246..8103
                     /locus_tag="VYR58_001442"
     CDS             7246..8103
                     /locus_tag="VYR58_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV3622576.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            8240..9061
                     /locus_tag="VYR58_001443"
     CDS             8240..9061
                     /locus_tag="VYR58_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEV3622577.1"
                     /translation="MILKIYNREYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTGQLLSAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFS
                     ELYICIIPTHNKSQFENIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            9075..9914
                     /locus_tag="VYR58_001444"
     CDS             9075..9914
                     /locus_tag="VYR58_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV3622578.1"
                     /translation="MKVIDQALLEKVIIERSRTSHKGDYGRLLFLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMSFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDAFGEDLVKQVFAGLRQNQILIVDGGALTILARTSLSFSSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASALTSFPQGTILVEKGSATRIWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFAGQFKQASLYERVAVATHLHSAIAQELAQEQYVVLPTEISNCLPKVMK
                     RYV"
     gene            10212..10895
                     /gene="rpiA"
                     /locus_tag="VYR58_001445"
     CDS             10212..10895
                     /gene="rpiA"
                     /locus_tag="VYR58_001445"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV3622579.1"
                     /translation="MENLKKMAGIKAAEFVKDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQIIAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            10909..12120
                     /locus_tag="VYR58_001446"
     CDS             10909..12120
                     /locus_tag="VYR58_001446"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV3622580.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            12122..12655
                     /locus_tag="VYR58_001447"
                     /pseudo
     CDS             12122..12655
                     /locus_tag="VYR58_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285096.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            12679..13488
                     /locus_tag="VYR58_001448"
     CDS             12679..13488
                     /locus_tag="VYR58_001448"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV3622581.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            13964..14359
                     /locus_tag="VYR58_001449"
     CDS             13964..14359
                     /locus_tag="VYR58_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEV3622582.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            14369..14944
                     /locus_tag="VYR58_001450"
     CDS             14369..14944
                     /locus_tag="VYR58_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV3622583.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            14969..15481
                     /locus_tag="VYR58_001451"
     CDS             14969..15481
                     /locus_tag="VYR58_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV3622584.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNFPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            16139..16849
                     /gene="deoD"
                     /locus_tag="VYR58_001452"
     CDS             16139..16849
                     /gene="deoD"
                     /locus_tag="VYR58_001452"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV3622585.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(16872..17396)
                     /locus_tag="VYR58_001453"
     CDS             complement(16872..17396)
                     /locus_tag="VYR58_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV3622586.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(17449..17685)
                     /locus_tag="VYR58_001454"
     CDS             complement(17449..17685)
                     /locus_tag="VYR58_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV3622587.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(17753..18673)
                     /locus_tag="VYR58_001455"
     CDS             complement(17753..18673)
                     /locus_tag="VYR58_001455"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV3622588.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            18863..19267
                     /locus_tag="VYR58_001456"
     CDS             18863..19267
                     /locus_tag="VYR58_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622589.1"
                     /translation="MKILKRYILELCFILSFALPFTKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFICSILIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            19483..20064
                     /locus_tag="VYR58_001457"
     CDS             19483..20064
                     /locus_tag="VYR58_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV3622590.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            20061..21338
                     /locus_tag="VYR58_001458"
     CDS             20061..21338
                     /locus_tag="VYR58_001458"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV3622591.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYCPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            21356..22018
                     /gene="deoC"
                     /locus_tag="VYR58_001459"
     CDS             21356..22018
                     /gene="deoC"
                     /locus_tag="VYR58_001459"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV3622592.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            22005..22394
                     /locus_tag="VYR58_001460"
     CDS             22005..22394
                     /locus_tag="VYR58_001460"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV3622593.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            22484..23536
                     /locus_tag="VYR58_001461"
     CDS             22484..23536
                     /locus_tag="VYR58_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV3622594.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            23680..25215
                     /locus_tag="VYR58_001462"
     CDS             23680..25215
                     /locus_tag="VYR58_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622595.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            25208..26266
                     /locus_tag="VYR58_001463"
     CDS             25208..26266
                     /locus_tag="VYR58_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622596.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALPHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KEFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            26269..27225
                     /locus_tag="VYR58_001464"
     CDS             26269..27225
                     /locus_tag="VYR58_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622597.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            27310..>27486
                     /locus_tag="VYR58_001465"
     CDS             27310..>27486
                     /locus_tag="VYR58_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV3622598.1"
                     /translation="MKLSCDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYS"
BASE COUNT         8062 a         4898 c         6136 g         8390 t
ORIGIN      
        1 gctaaatatc ataaacgcct tcaaatcgtt ctatagtaaa atgaaacaag aacaggacaa
       61 attgatcagg acagtcaaat cgatttctaa caatgtttta gaagtagggg tgtactattc
      121 tagtttaaat ccactatatt tggggagtga tagaaaagcc cttcataagc cagtctactt
      181 gttcaggtgc gagagctttg acatcctttt ctgtactggg ccaagtcagt tttccgttct
      241 caaagcgttt atatagtatc caaaatcctt gaccatccca gtaaagggct ttaaagcggt
      301 ctttacgtcc accacaaaag agaaagactt gaccggagaa aggatccaat tcaaagtggg
      361 ttttaacgag ataagccagt gaatcgattc cttgtatcat atctgtcttg ccacaaacaa
      421 ggtgaacttg acctaaatca cttagttgaa tcatcatagt acaatacttt tcctccgata
      481 attatttttt atctagtata ctggaagttg gggaattagg atagatacct tgttatgacg
      541 cgcttacgta acttgtaact agctgcctag tttgatcttt gcttcttcat tgattagcag
      601 cagatttcaa aatgataaaa acgtataata gtgggtgtag aaactcttgc tactatgcgt
      661 tttattatgg aaagacttat tggactttct ctcaaatcga gtttttactc aattttctta
      721 cttgattggg attgaaattc caattaattt ctctgagtag agtgtcttga tattggcttc
      781 atcaacagag gccttatcaa ttttacgttt caagaaaaat tcttgaatgg tttcgatttc
      841 aggctcacga atagcacggt gtttgtttga gatgaggatt tcatagtgaa gcggagcttg
      901 ggtaaaaata acatctgtat tccctgcaga ataaacctca acaagggttg catcggtact
      961 ttctagctga ctttttacaa gttgcgagtg tgagtttgtc gtattgataa gcttcataat
     1021 atttcctccg attttctaat tctattatag cactttttga ataaagtcgc ttgatttata
     1081 ctcaatgaaa ataaaagagc aaactaggaa gctagccgca ggctatactt gagtatggta
     1141 aggcgacgct gatgtggttt gaattttatt ttcgaagagt attagtcaat cttatgctgt
     1201 tttttccaag attcaatggc ccatttatgg ctaccacgtt taaggttttt gatagcctcg
     1261 tcaataggga accaggcaat atgattaaag ttttctagtg gcttttgtac ttctttgaaa
     1321 ggagttgctt catagaggta ggcaggattg tagtagtagg tatcacgatg acgagaatag
     1381 aaatattcgt cagcttgtcc gtaataggta ccaatttctg ctgtgaaacc aagctcttca
     1441 atcaactcac gctttagggc ttcctgatga ttttcacctg cttcaatttc tccacatggt
     1501 aggaaccaag caccatttgg ttcttgaaca agaacaattt gtttttgttc aggattaggg
     1561 ataactgcat atacgccata gcgagcaata tagtctgtat tcgctttttt tctccgaaag
     1621 ttgggtttgc cattgcattt tcctcattat ctagtatcgt tattattata gtgaaatgaa
     1681 ccaaaaatag tacacaatgt ggtataatct tcttatggca tattcaatag attttcgtaa
     1741 aaaagttctc tcttattgtg agcgaacagg tagtataaca gaagcatcac acgttttcca
     1801 aatctcacgt aataccattt atggctggtt aaagctaaaa gagaaaacag gagagctaaa
     1861 ccaccaagta aaaggaacaa aaccaagaaa agttgataga gatagactta aaaactatct
     1921 tactgacaat ccagacgctt atttgactga aatagcttct gaatttggct gtcatctaac
     1981 taccatccac tatgcgctca aagctatggg ttacactcga aaaaaagaac cacacctact
     2041 atgaacaaga cccagaaaaa gtagccttat ttcttaagaa ttttaatagt ttaaagcacc
     2101 tagcacctgt ttagattgac gaaacaggat tcgatactta tttttatcga gaatatggtc
     2161 gctcattaaa aggtcagtta ataagaggca aagtatctgg aagaagatat cagagaattt
     2221 ctttggttgc aggtctaaca aatggtgagt taatcgctcc aatgacttac gaagagacga
     2281 tgacgagcga cttttttgaa gcttggtttc agaagtttct cttaccaaca ttaaccacac
     2341 catcggttat tattatggat aatgcaagat tccatagaat gggtaagtta gaactcttgt
     2401 gtgaagagtt tgggtataac tttttacctc ttcctcccta ctcacctgag tacaatccta
     2461 ttgagaaaac atgggctcat atcaaaaagc acctcaaaaa ggtattacca agttgcaata
     2521 ccttttatga ggctcttttg tcttgttctt gtttcaattg actatagcag attgaaataa
     2581 gatgagaaca aatcgattgg gaaagtaaaa ttaatttcta taaatgtttt agcaattgtt
     2641 tcgtactatt tcagattcag tctactatat atcataatgg acaaagggca agctgtcaag
     2701 aaattacagt tattttagta aaaaaagaag cagaaaaatt tcattttcta ctccttttct
     2761 ataggattta tttttctttt tcagaacttt taacttcagc ttttttggca gatttaatct
     2821 gaatgtttcc cttgctagtc ataactgctt tgagatcttt ttcgcttgga ttttcaaggt
     2881 agtagtcagt gattgtgtcc tcaatatagt cttgaatagt ccgacgaagt gggcgtgctc
     2941 ccatttttgg atcataacct aggtcaacca acttttcctt gaccttgtca gttacatcca
     3001 aacgaatgtt gttgctagag aggcgcttgt taacatctgc tagcatgagc tcgacaatct
     3061 gaaggaggtt atccttgctg agagccttaa attcgataat gccatcaaaa cggttcataa
     3121 actctgggct aaagaagtta ccgagttcac cgaggacaga attggtacgt ccttctctag
     3181 cagcaccaaa tccaacgcta gcttcggtct ttcctgtacc tgcatttgag gtcatgataa
     3241 tgatggcatc cttgaagcta acggtgcgtc cttgcccgtc tgtcaaacga ccatcgtcca
     3301 agacttgaag aaacatgtgc ataacatctg ggtgagcttt ttccacttca tcgagaagga
     3361 tgagagaata cggattgtgg cgaacttttt cagttaattg accagcctca tcatagccaa
     3421 cataacctgg aggagcgccg accaacttag ccacactatg tttttccatg tattcactca
     3481 tatcaaagcg aatcatacta tcagcagaac caaaaagttc gatagccagt tgtttggaaa
     3541 gttctgtctt accgacacca gttggtccaa cgaagaggaa gcttccgatt gggcggttag
     3601 gggtaccaag tccgacacga ttacggcgaa tagccttggc aatcttatcg actgcatcat
     3661 cttggccaat aacatgagac ttgagatctt cggctagatg gatgagttga gattgttctt
     3721 tctctttcaa atcaccaaca gggatattgg ttttctgctc gataatgtgc tcaatagttt
     3781 tctcgctgat gataggagta tcctggtctg tgatcttttt cttttgcatt tccttatact
     3841 tggcaatctg gtcgcggaag taggccgcct tctcaaaatc ttcttctcgt gtagcttgag
     3901 acttgagatt ttcagcctca atcaagcgct gatcaattac tttaggatcc acaaaattca
     3961 aggtcaagtt catcttagaa ccagcttcat ctaggaggtc aatggccttg tcaggcaaga
     4021 agcgatcttg gatgtagcga ttggaaagag ttgcagctgc ttcaatcgca gcatcggtat
     4081 attgaacgtg gtggtaatct tcgtatttct tttgaatccc tttgagaata gtgattgttt
     4141 catccaccgt tggttcatcg actttaacag gctgcatacg acgctcgagg gcagcatcct
     4201 tttcaatgat acggtattca ttgagggtag tagcaccgac tagttgcagt tctccacgag
     4261 caagggctgg cttgaggata tttcctgcgt ccatattacc atcactcgca gaaccagcac
     4321 caacaatttc atggatttca tcgataaaga ggatgatgtc ttcacgtttg cgaatttctt
     4381 ccatgagttt ttgcatgcgt tcttcaaatt gtcctcgaat ccccgttcct tgaactaagc
     4441 taaccacatc cagacggatg acttgtttac cttggagttt atgtggcaca tcgccatcga
     4501 caattttctg agctagacct tcgacaacgg ccgtttttcc gacaccaggt tcaccgataa
     4561 ggacaggatt attcttggtt ctacgattga gaatctcgat gacacggata atctcatcgt
     4621 cgcgcccaat aacggggtca atgtctccac gacgggcaat ttcagttaca ttaataccaa
     4681 attcttccag caggcctttt tcttggctag gtggcggagt ttgagcagat ccacgatttt
     4741 gggaaccata accgccgttt ccaccgtaac ctccacctga ttgggttggg ggaataggag
     4801 gagtattgct agaaggtctg aaattgttta gatcattgaa gaaatcacca aagggatcga
     4861 agtcacgatt gttcagatcc gtcatacctt tgaagaggct attgttagga tctgttttga
     4921 taatcttata gcagttttga cagaggtcaa tttgtttttg ttttccattg agattggtgt
     4981 aaagatgaat tgttgagtcg ttaattttac agttttgaca aagcatacat ctacctcatt
     5041 tctttcttta gcctgacttg tttaaaggtc aaaaatagtc aaattctata ctctcattat
     5101 aacaggattg gggtgtaaag caagtaaaaa gattgaagct ttgagaagtt gttacaatga
     5161 aaatttttgt gaatttggac tataaaaaaa tcctatttgt gagacaaaaa ggattttact
     5221 tagacatgca gggacaatcc caacttgttt tagattagta gagaagttcg taaatttcca
     5281 ttgcgattaa gtcaatgcta tcaaacgtat acgtttcgcg atcttctacg tcacgaaggg
     5341 taaagattgg gccgttttct tcgtcgtggc tgtacgcaac ttctgcaaca acaactcctt
     5401 cgcgttcaaa attacgtttt aaatttccgc catcgtttgc cattgcttca aggcggttga
     5461 tgattctaac caaatgtgat tccattttga ttctccttca tttcttatcg ttactatttt
     5521 accataaagg agggcaactt gactagaaaa aactaagatt tctcgctaat tctgctagtt
     5581 taaagatttt taaataaatt ggataaaaaa tttaaatttt aattcaaaac atgttataat
     5641 catacagtat tctattttag aaagcagtgt gactatgaat ttttcttttt tacctaagta
     5701 tttaccttat tttaactatg gggctgttgt gacgattctt atttctatct gtgttatctt
     5761 tttgggaact attttgggtg ttgtcttggc ttttgggcaa cgttcaaagt ttaaaccgct
     5821 tgtttggttg gccaacttgt acgtttggat tttccgtggg acaccgatga tggttcaaat
     5881 tatgattgcc tttgctctta tgcatatcaa tgctccgact attcagattg gaattttagg
     5941 tgttgatttt tcgcgtctga ttccagggat tttgattatc tctatgaata gtggtgctta
     6001 tgtttcggag actgttcgtg ccggaatcaa tgcggttcca aaaggtcagc tagaggcggc
     6061 ttattcgcta gggattcgtc ttaaaaatgc gatgcgttat gtgattttgc cacaagcagt
     6121 caaaaatatc ttgccagcat tggggaacga atttatcacc attatcaagg acagctccct
     6181 cttatcagct attggggtca tggagttgtg gaatggggct acaacagttt ctacaacaac
     6241 ctatctacct ttaacaccac ttttatttgc agcattttac tacttgatta tgacctctat
     6301 tctgacagta gccttgaaag cttttgaaaa acatatggga caaggagata agaaataatg
     6361 acagaaacct tgataaaaat tgaaaattta cataaatctt ttggaaagaa tgaagtattg
     6421 aagggcatca acctcgagat taaaagagga gaagttgtcg ttatcatcgg tccttcaggg
     6481 agtgggaaat ctaccttgct tcgctctatg aatttgttgg aggaagcaac caaggggaag
     6541 cttatctttg agggagtcga tattacggac aagaagaatg acctgtttgc catgcgtgag
     6601 aagatgggca tggttttcca acaatttaac ctctttccta atatgactgt gatggaaaat
     6661 attaccttgt cacctatcaa gactaaaggt gaaagcaggg aagttgctga gaagagagcc
     6721 caagagcttt tggaaaaagt tggtttgcca gataaggcag acgcttatcc acagagtctg
     6781 tcgggtgggc agcaacaacg gattgccatc gcgcgtgggt tggctatgga accagatgtt
     6841 ttgctctttg acgaaccaac ttcagccttg gatcctgaaa tggtaggtga ggtattggct
     6901 gttatgcaag accttgccaa gtcagggatg actatggtta tcgtaacaca tgagatggga
     6961 tttgcccgtg aggtggcaga tcgtgttatc tttatggcag acggtgtggt tgttgaagat
     7021 gggacacctg agcagatttt tgaacaaacc caagaacaac ggactaaaga tttcttgagt
     7081 aaggttttat aatctatttt aaaatttcaa gacaagatta gtgaaaagtt caaccagagc
     7141 tttttcttat agtttgaaac tataggataa cctaggaaag aagtgttaga gggcactagc
     7201 agtttttggt ataatggaag atatttgaaa gaaaagagaa gtgatatgac acagattatt
     7261 gatgggaaag ctttagcggc caaattgcag gggcagttgg ctgaaaagac tgcaaaatta
     7321 aaggaagaaa cagctctagt gcctggtttg gtagtgattt tggttgggga taatccagcc
     7381 agccaagtct acgttcgcaa caaggagagg tcagctcttg cggctggttc ccgtagcgaa
     7441 gtagtgcgag ttccagagac cattactcaa gaggaattgt tagacctgat tgctaaatac
     7501 aatcaggatc cagcttggca tgggattttg gttcagttgc cattaccaaa acacattgat
     7561 gaagaggcgg ttctattggc tattgaccca gaaaaggatg tggatggttt ccatcctcta
     7621 aatatgggac gcctttggtc tggacatcca gtcatgattc catcaacacc tgcaggaatt
     7681 atggaaatgt ttcatgaata tgggattgaa ttagaaggta aaaatgcggt tgtcatcggt
     7741 cgttctaata tcgttggaaa acccatggct cagcttcttt tggccaagaa tgcaacagtg
     7801 actttgaccc actcacgcac ccataatctt gctaaggtgg ctgctaaagc agatattctg
     7861 gtggtcgcaa tcggtcgtgc caagtttgtg actgctgact ttgtcaaacc aggtgcggta
     7921 gtcattgacg ttgggatgaa tcgtgatgaa aatggtaagc tctgtgggga tgtggattat
     7981 gaggcagttg ccccacttgc tagctatatt acgccagtcc ctggaggtgt cggccctatg
     8041 accattacta tgctgatgga gcaaacttat caagcagcac ttcggacatt ggatagaaaa
     8101 taagagaaaa atcgctgaag agagtgtatt ttctatagct atatttaaaa tggcagaaat
     8161 gaatattaaa ttttagatat aagattacaa aaggaggtct gcgcctcctt tttgttgtat
     8221 aatggagtga ggtgattaga tgattttaaa aatttataat agggaatata gtttacaatg
     8281 ggatggaata tactacctag cactaattga ttatccaaat attcaagagt gggaattaga
     8341 aaaaattgct aaatttatag cttacgaaaa acttcataaa cgtcaaacaa gtattgagtg
     8401 tgctgattct tgtttaaaaa aagaaatttt agattacatc tgtcagcatc cctttctgcc
     8461 accatttacc cctacagata aaagagtagc ctcgacttat gatctacata agaggttagt
     8521 gacttcagac tactgtagtc atactacgac tatagatgca gcgatttcta tctttaaaac
     8581 aggtcagctc ttatctgctg tgaaagcctt taggcgagat gctgaagagt tggttttgga
     8641 tagtagaaat gctgcatcgg atccgataga ttattttgat tatgtcatgt tagggtggtc
     8701 aaatacaagt tctggttatc gattagcgat ggagcgttta ttaggtcgag ctccttcaga
     8761 gaaagaatta caagacaagt ttattcctgg agtgagtttt cattttatct atacagattt
     8821 gattaaagtt actggttata tttttgatgg ctaccatgtt gcaaaaatta aggacatgtt
     8881 gaatttattt agtgagttgt atatttgtat tattccaact cataataaga gccaatttga
     8941 aaatattatt ccaactaaaa tacaagatag ggtgcattat cttgactatg ctggagaaga
     9001 cttagaagag tggactaaga aagtctatca agttgtttta aaacaatcag ataaaggata
     9061 gttgaggaag aacgatgaaa gtgattgatc aagccttact agaaaaagtt attattgaac
     9121 gttctcgtac tagtcataaa ggagactatg gccgtctgct gtttcttggt ggaacttatc
     9181 cttatggtgg tgccatcatc atggctgctt tggcagctgt aaaaagcggt gcaggattgg
     9241 tgaccgttgg aacagatagg gaaaatattc cagccctgca cagccattta cctgaggcta
     9301 tgtccttttc tcttcaagac cagcagttgt taaaagagca attggagaag gcagaagttg
     9361 tcttgctggg gccgggttta cgagacgatg cttttggaga agatctagtt aaacaggtct
     9421 ttgctggctt aagacaaaat cagattttga ttgtagacgg aggtgccttg accattcttg
     9481 ctaggacaag tttgtcattt tcctcaagcc agcttatcct aactcctcac caaaaagaat
     9541 gggaaaaatt atctggaatt acgattgaaa agcaaaagga agatgcaacg gctagtgccc
     9601 taacttcctt ccctcaagga acaattttgg tggagaaagg ttcagctact cgtatttggc
     9661 aagctggcca atcagattat taccagttac aggttggcgg tccctatcag gcgactgggg
     9721 gaatgggaga tacgcttgct gggatgattg caggatttgc aggccagttt aagcaagcta
     9781 gtctttacga acgtgtggca gtagcgaccc atcttcattc agccatagcc caagaactag
     9841 ctcaagaaca gtatgtggtt ttgccaacgg agattagtaa ttgtcttcct aaagtaatga
     9901 aaagatatgt ctaaaatagt tagacaaaaa atattgataa tttgtatcat tattcttaat
     9961 tcacaaaaaa cgaacgttta gtattcttct cgctaagaaa ctaaatttgt tcgttttttt
    10021 actcttgtaa atctattttt gttagagttg atttggttta catccgtact taaagtgatt
    10081 tgtcagagtt ctgcttttat taaaaaaatt taatttcaag gataaataag cagtattcta
    10141 aaggtacttt tagatgaaat aaaagccttt acatggtata atagaggtag ctctttaatg
    10201 gaggtgtttg agtggaaaat ctgaagaaaa tggcaggtat caaggctgct gagtttgtca
    10261 aggatggaat ggtcgttgga cttggaacag gctcgactgc ctattatttt gtcgaagaaa
    10321 tcggtcgtcg tatcaaggaa gaaggattgc agattatagc tgtaacgact tctagtgtga
    10381 ccactaaaca ggcagaaggc cttaatatcc cactcaaatc tattgaccaa gtagactttg
    10441 tcgatgtgac agttgatggc gcagatgaag tggatagtca gtttaatgga atcaaaggtg
    10501 gtggtggtgc tcttctgatg gagaaggttg ttgcgacacc atcaaaagaa tacatttggg
    10561 tggtggatga aagcaagctg gtcgaaaaac taggtgcttt taaattgcca gtagaagtgg
    10621 ttcagtatgg tgcagaacag gtctttcgtc gttttgaacg agctggctac aaaccaagtt
    10681 tccgtgaaaa agacggccaa cgttttgtga cggatatgca gaattttatc attgacctcg
    10741 ccttggatgt cattgaaaat ccaattgctt ttggacaaga attggaccat gtcgttggtg
    10801 ttgtggagca tggtttattc aaccaaatgg tggataaggt catcgttgct ggacgggatg
    10861 gagttcagat ttcaacttca aaaaaaggaa aatagaaggg ggcataagat gtctaaattt
    10921 aatcgtattc atttggtggt actggattct gtaggaatcg gtgcagcacc agatgctaat
    10981 aactttgtca atgcaggggt tccagatgga gcttctgaca cactgggaca catttcaaaa
    11041 acagttggtt tgaatgtccc aaacatggct aaaataggtc ttggaaatat tcctcgtgaa
    11101 actcctctta agactgtagc agctgaaagc aatccaactg gatatgcaac aaaattagag
    11161 gaagtatctc ttggtaagga tactatgact ggacactggg aaatcatggg actcaacatt
    11221 actgagcctt tcgatacttt ctggaacgga ttcccagaag aaatcctgac aaaaatcgaa
    11281 gaattctcag gacgcaaggt tattcgtgaa gccaacaaac cttattcagg aacggctgtt
    11341 atcgatgatt ttggaccacg tcagatggaa actggagagt tgattatcta tacttcagct
    11401 gaccctgttt tgcagattgc tgcccacgaa gacattattc ctttggatga attgtaccgt
    11461 atctgtgaat acgctcgttc gattaccctt gagcgtcctg cccttcttgg tcgcatcatt
    11521 gctcgccctt atgtaggtga accaggtaac ttcactcgta cggcaaaccg tcgtgacttg
    11581 gctgtatctc cattttcccc aactgttttg gataaattga atgaggctgg tatcgatact
    11641 tatgctgtgg gtaaaatcaa cgatatcttt aacggtgctg gtatcaacca tgacatgggt
    11701 cacaacaagt caaatagtca tggaattgat acactattga agactatggg acttgctgag
    11761 tttgaaaaag gattctcatt cacaaaccta gttgactttg atgcccttta cggccatcgt
    11821 cgtaatgctc acggttaccg tgattgcttg catgagtttg atgaacgctt acctgaaatt
    11881 atcgcagcta tgagagagaa tgaccttctc ttgattactg cggaccatgg aaatgaccca
    11941 acgtatgcag gaacggatca cactcgggaa tatattccat tgttggccta tagccctgcc
    12001 tttaaaggaa atggtctcat tccagtagga cattttgcag atatttcagc gactgttgcc
    12061 gataactttg gtgtggaaac tgctatgatt ggggaaagtt tcttagataa attggtataa
    12121 gatgacgcgc tatgctttgc tggtgagagg tatcaatgtt ggtggtaaga ataaggtcgt
    12181 catggcggag cttcgtcaag aattgacaaa cttgggactg gaaaaggttg agagctacat
    12241 caacagtggc aatattttct ttacttcgat agattccaaa gcccaattgg ttgaaaagct
    12301 agagactttc tttgcagtcc attatccatt tattcagagc ttttctttac tgagtctaga
    12361 ggactttgag gcggaacttg aaaatctacc agcttggtgg agcagagatt tggcacgaaa
    12421 agattttctc ttttacactg agggtttgga tgtggaccaa gtcatcgcga cagttgaaag
    12481 tttagagctg aaagatgaag tgctttattt tggaaaactt gggattttct aggggaaatt
    12541 ttctgaagaa tcctattcta agactgccta tcataagtac ttgctgaggt gcctttctac
    12601 cgccacatta ctattcgtaa tgctaaaacc tttgacaaaa ttggtcaaat gctaaaaaaa
    12661 taataaagga gacacacaat gacattttta aacaaaatcc atgaaactgc tactttcctg
    12721 aaagaaaagg gaattgcagc ccctgagttc ggtctaatcc ttgggtcagg acttggagaa
    12781 ttggcagaag aaatcgaaaa tccagttgta gtagactatg ctgagattcc aaactggggc
    12841 cgttcaacag tagtcggtca tgctggtaaa ttggtatatg gtgaactggc aggtcgcaag
    12901 gtcttggctc ttcaagggcg tttccatttc tatgaaggga atcctctgga agtggtgact
    12961 ttcccagttc gtgtgatgaa agttcttgga tgtgaaggtg ttattgtaac caatgcagct
    13021 ggcggtatcg gatttggtcc tggtaccttg atggctatct cagaccatat caacatgacg
    13081 gggcaaaatc cattgatggg tgaaaacttg gatgactttg gcccacgttt cccagatatg
    13141 tctagggcct acacaccaga ataccgtgct actgcccatg aagtggctaa aaaacttaat
    13201 atcaagcttg atgaaggtgt ctatatcgga gttactggtc cgacttatga aacaccagca
    13261 gaaattcgtt cctataagac actgggagca gatgcagttg gtatgtctac ggttcctgaa
    13321 gttatcgtgg cagcccactc tggcttgaaa gttctgggaa tttcatgtat cactaacttt
    13381 gcggctggtt tccaagaaga actcaatcac gaagaagttg tagaagtgac tgaacgtgtt
    13441 aaaggtgatt ttaaaggctt gcttaaagcg attcttgctg aattgtaaga aaaaagattt
    13501 aaaaggggga gtgcctctgt cttttcagga ttgactgcct atccgtatta aagaagaaac
    13561 agaggaatac tatgagcttc ttcctgctct tataactgaa agaagcggaa gaataggtgt
    13621 gtctgatctg atagctagca ttgtgaaaga caagattcta ggatactagc attagcttcc
    13681 tagccaagca gactagtatg ataaggagag atgagaatga attgactttc tgaatttctc
    13741 agtcttatca tatatagcac aatgagattt cgcttgagtc tgcttgtaaa taaacgaaaa
    13801 gaaagataag aaataatgaa aattggtcaa cgaattatgc gctttggcat aaaaaattaa
    13861 gtatcggagt tgtatctgtt gtagtcggct ttgatttcta gctccagctg gaatttcagc
    13921 caatgaagta aagcaagatg taacaactga agtggtaata ggtgtgctag attctaagga
    13981 ggaattgaaa gagtcagaaa atgatgctcc aaaactagaa actcctctta gagaggagcc
    14041 aagactagct cctcaaacgc ttccggaagc aagtgaagtt cttgaaaaca aaagggaaga
    14101 gtcaaaagta gagataacag agccagctca agcggatgac atccgcaagg ttgttgggga
    14161 attagccaag gatataagta ttactaagtt gtatatgaca ggtcattctc ttggaggcta
    14221 cctagctcag attgcagcgg ttgaagatta ccaaaaatat cctgattttt ataaccatgt
    14281 attgaggaaa gtgacaactt tcagtgctcc taaagtgatt acttccagaa ctgtttggga
    14341 tgctaagaat ggtttctgag atgttggttt ggaaagtcgt aaattagctg ttagtggaaa
    14401 aattaagcat tatgtggttg ataatgacaa tgttgtgact cccttgattc ataataatcg
    14461 tgatattgtt acatttacag gtaattcacg ctttaaacac cgttctcgtg gctattttga
    14521 aagtccaatg aatgatattc ctaactttaa tattggtaaa caagctacct tggataaaca
    14581 tggttatcgt gatccgaaat tggataaagt gcgattcttt aagaaacagg ctctacctca
    14641 atcttctagt caaccaagcg ctgaaccaat ggaaaatatt gccttaggaa aacaggttac
    14701 tcaaagttcg acagctttcg gaggagatgc tagaagagct gtggatggca aagtcgatgg
    14761 taactatggt cacaattctg tcactcatac aaacttccaa tctaagcctt ggtggcaagt
    14821 agatttggct aaagaagaaa ccattcgcca aatcaatatt tacaaccgaa cagacactgc
    14881 ccaggataga ttggcaaact ttgatgtcat tcttttagac agttctggta aagaaattga
    14941 gtgaaaacgt ataatatctc ctaaagatgt gtcagcacaa attacgatta accataaaaa
    15001 agcgcgctat gttcggattg ggctagaagg ctataatgcc ctcagtcttg cagaagttga
    15061 agttttccgc tttatagcta cgaatgctga aacggcgaca caagtttcta agccagttca
    15121 accaatcagt cagactcctg tgaaagataa aacattgaca attcaacaca gtggagctta
    15181 cattgcccgc tactccataa cttgggaaga agttccagta gataaagatg gaaaccaagt
    15241 tgttcgtagt cattcttggg aaggaaacgg ttgcaaccag actgcaggtt ttgtcctcaa
    15301 cttcccaatc aaagaaaata tgagaaatct gcgagttaag attgagaaaa agacgggcct
    15361 actatggaat agatggcaaa caatctatga aaacagacca attttagctc aaccccaccg
    15421 taaaattacc cattggggta cgacattgaa ttccaaggtg agtgacgatg atgtcttgta
    15481 atctgatggt acaatgacag ttagtttgtc tagtttataa gaaagtacta tctgagcttg
    15541 aatagaactc aggtagctct ctgtgaaaga acaaaattaa tactcaatga aaatcaaaga
    15601 gcaaactagg aaactagccg caggttgctc aaagcactgc tttgaggttg tagataagac
    15661 tgacgaagtc agtcacatat ataatccaag gcgacgttga cgtggtttga agagattttc
    15721 gaagagtata aacagaaagg tagagcgcgt gttctaattt gaacacgagt agaaaacttt
    15781 tctaaaaaca aaaacgaaag gatgggtaaa ctgtattcgc tgaactgaat acgggcgact
    15841 ctcctctaaa tcaaaattaa gaaagaaagg aattgacccc accctaaaag cagtgggaaa
    15901 aagatagttg gtctagcgag catcgctcac tgcgcccaac tcctattttc ccttcgcttt
    15961 ttgacgggtt tggtatcttt ctcaatataa aatataaaat aaagaaaggt agagcgtgtg
    16021 ttttgatttg aacacgagcg gaaaactcgg aaaatagata atctgactga aaaatcagga
    16081 tttctcgtcg gcttcctaat tttcagtcgt tttcttctcg ctctttgtat cataaattat
    16141 gtctatccat attgctgctc agcagggtga aattgctgat aaaattcttc ttcctgggga
    16201 tcctcttcgt gctaagttta ttgcggagaa tttccttgat gatgctgttt gttttaacga
    16261 agtgcgtaac atgtttggtt acactggtac ttacaagggt cactgtgtat ctgtcatggg
    16321 aactgggatg ggaatgccat ctatttcgat ttatgcgcgt gagttaatcg tagactacgg
    16381 tgtgaagaaa ttgattcgtg tgggaactgc aggttctttg aatgaagagg ttcatgttcg
    16441 tgaattagtt ttggcgcagg cggctgcaac caactcaaac atcgttcgta atgactggcc
    16501 acagtacgat tttccacaaa ttgctagctt tgatttgctt gataaagcct accatatcgc
    16561 caaaaaactt ggtatgacta ctcacgttgg gaacgttttg tcatctgatg tcttttactc
    16621 aaattacttt gaaaagaata tcgagcttgg taaatgggga gtcaaggctg tggaaatgga
    16681 agcagcagct ctttactatc ttgctgccca ataccatgtt gatgcgctag ctatcatgac
    16741 catctctgat agcttggtca atccagacga agatacaact gcagaagaac gtcaaaatac
    16801 cttcactgat atgatgaagg ttggtttgga aaccttgatt gcagaataat tatagccaaa
    16861 aaggaagccc tttatgaatt gtaggacttc cttttcttat ccagaaattg atctagttct
    16921 ctctgatttc gaagaatagt gactttatgt gaatattctt ggcaaagttt ttggtaattt
    16981 tctttttgag ttttgctacg cccatcccaa agaatccatc tgataaactc ccactcaaag
    17041 cgttcagggc aatctgccgc catactttct ctgacttttc cacggtattt aagataacgc
    17101 ttaaaggctc taaagagaca ggtcaatggc aaaaaattga gaaagatgat ttggtcagct
    17161 tcttgcattc gttcttggta gtagcaccaa gaataattac catcgatgac ccaagcttta
    17221 tgcttggtga gaaagttttt tatctcggtt aacatccatt cgcagtcact gtcttgccaa
    17281 ccaggttgaa attggagtgt gtccatgtgc agttttggaa tggagtagta gttagataac
    17341 ttttctgcta gagttgactt accagaacca gaatatccga taattgcgat tttcattttc
    17401 taccttttcc tatttggaga caaaaaaaca gcctctatgg actgtttctt atttagcaag
    17461 tttagctgaa agacgagctt tatcgcggct tgctttgttt ttgtgaatca aacctttagt
    17521 ttctgcttta tcgatagctg agctagcagc acggaaaagt tcttcagatg ggtttgcttc
    17581 gaaagctttt atagcagtac gcatagctga tttttgagct gagttctttt cgttttgttt
    17641 aacgttcaat tcagcgcgtt tgatagctga tttaatgttt gccaatgttc ttacctccat
    17701 atttactaac tataccatta tatatgaaaa cttacgtttt gacaagggaa aattactttt
    17761 ttaagtaaat ttcatcgatt tcatggttct tgcttttatg aagaatcact tctgcacgat
    17821 ttctggttgg ttcaatataa ttttgcagat ttgtgagatt gatactggtc cagacctgat
    17881 gggcaaagga ctccacttcc ccaatcggca tctgagtaaa acgataatag tagctatcag
    17941 ggtcgttttg ggctaggctc agcattttca agaaacggtc cagataccaa ctttcaatat
    18001 catccactcc agcatctaca tagatggaaa agtcaaagaa gtcagtgata tagagacgat
    18061 cgttttgtgg attttgaaag acattaattc cctcaacaat tacaaaatca gcagctttga
    18121 cactttgttt cttttcgggt acgatgtcgt aaacttcatg agaatagaca ggaatatcta
    18181 catcttgtcc atttttgatg cggtccaaga agttgagaag agcttccata tcatagcttt
    18241 caggaaatcc tttacgattt aaaatcccct gctcaatcaa ggtttgattg ggatagagaa
    18301 aaccatcagt tgtaaccaac tcaaccgtag catctgtaaa cgtacgggac agtaggattt
    18361 gaagtaggcg actggttgtg gattttccaa cggcaacact cccagaaacc ccaataataa
    18421 aaggttgaga tttactttca cgttggagga aaattccttt tgaaaaggct aaatcttcct
    18481 tagttcgctt gtaaatctga atcagatgag ccaaggggag atagatatct gtaacgtctt
    18541 ggagactgat ttggtcatta aaactcttga tagattccaa ttcttcttct gtcaaaggag
    18601 gtgttgtctt tcgatgtaaa gattgccaag tctggcggct gattttttca aaatgtaaaa
    18661 attcgttggt catttgtttt cccctagata ttttgtctat cataccataa aaagctaaaa
    18721 aaataaagcg gtttcttgaa tgtggtaagt caatggtata tagtataagt gatcaattta
    18781 ttgatgaaat aggagataga ttctactgat ttataagctt ataaaggggg ctttttagtt
    18841 cacaacttat aggaggtgta ctatgaaaat cttaaaacgt tacatattgg aactctgttt
    18901 tattttaagt tttgctttac cttttacaaa aggagccaat gcagataatg gtagatgctt
    18961 tgtggaaacc tattacggtt ttactttttt gatggaacat gctattgtaa cagctgtctt
    19021 tatctgttcg atcttaattg ctttcttact aaaaaaacga tgggcgaaat ggattgctgc
    19081 tggtagttat tgctttttag tcctatggat tgcgacagag ggttatttct tccgcatgtc
    19141 actagaagat ttgatacgac tttggacaag tttggaaatc ctgacacaaa cgtatcagtt
    19201 gggcttttat ctaaacattt tgttgggaat tttgttgata ataaagtatt ttaaggttaa
    19261 gcaatagaaa taataatctg cctgattata gatgataaac tttttgtttt tatctggact
    19321 gtgatattta tagttctaaa tggtttatta tttataagtg ttgaaagaga ttgaagaaaa
    19381 tggcttcgtg actcgctttc ttcggtcttt ttcgttttat tatcaatttg taaacgattt
    19441 acaatttgag tcaaattatg gtaaaatagt gtcatgagta aaatgtatta tgcagaaaat
    19501 cctgacgctg ctcacgacat tcatgagttg agagtagagt tgttgggaca aaaaatgacc
    19561 tttttaacgg atgcgggtgt ttttagcaag aaaatagttg actttggaag tcaactcttg
    19621 ctcaagtgtc ttgaggtcaa ccaaggagaa actgtccttg atgtaggctg tggttacgga
    19681 cctttgggtt tgtccttagc taaggcttat ggagttcagg ctactatggt tgatatcaac
    19741 actcgtgcct tggatttagc tcggagaaat gctgaaaaaa ataatgcaaa agcgacgatt
    19801 ttccagtcca acatctatga acaagttgag ggacattttg atcatgtcat ttccaatcct
    19861 cctatccgtg cgggcaagca agtcgttcat gaaatcattg agaaaagtaa agatttcttg
    19921 gaaactggtg gggatttgac aatcgtcatc cagaaaaaac aaggggctcc aagtgctaag
    19981 tccaagatgg aggatgtgtt tggtaattgt gaaatcctta aaaaagacaa aggatactat
    20041 atccttagaa gtgtgaaaga atgagagcag ttgatttaat acaaaaaaaa cgagacggtc
    20101 aagaactgac ttcaagtgaa attgaatggc tgatagaagg ctatgtgtca ggaactgttc
    20161 ctgattatca gatgtctgcc tttgctatgg ctgtttattt taaaggaatg acgactcgtg
    20221 aaatttctga tttaacgatg aatatggtta agactgggca agagtttgac ctgtcagcca
    20281 ttgatggtgt gaaagttgac aagcattcta ctggtggtgt cggcgataag gtaaccttga
    20341 ttttagctcc tcttgttgct agcttcggtg tgcctgtagc aaaaatgagt ggtcgtggtc
    20401 ttggccatac aggcggaaca attgataaat tggagtccat taagggctat caagtagaac
    20461 gtagtcaaga ggattttatt cgtcaggttc aggatattgg agtatctgtc attgggcaat
    20521 cagaccagct ggtcaaagca gataagcttc tctatgccct tcgtgatgtg accgcaactg
    20581 tcgacacgat tcctttgatt gcgagttcgg tgatgagcaa gaaaattgcg gcaggggcgg
    20641 atgctatttt gctagacgtg actgtcggtg agggtgcctt catgaagacg gttgatgagg
    20701 cgcgtgagtt ggctcaaact atggtagatc ttggtaaggt tgttggacgg aagacagtag
    20761 cagtgattac ggatatgagc cagcctttgg gacgagcgat tggaaatcgt ctggaaatcc
    20821 ttgaagcatt ggagattttg caaggtcaag gacgtcagga tattacccac tttatttgtg
    20881 aattggctca aattatgctt ggtttggcaa atgttaacaa aactgttgaa gaagttcgcc
    20941 aacatcttga gaatggtcaa gcactggcta agtttgagga aatggtgcaa gcccaaggtg
    21001 gagacttgga agacctctat tgtcctgtaa atgtagctca tgtggtggaa atccctgctc
    21061 aggaaacggg tgtcatttca gctcttccag ctatggactt tggtctttat gccatgaggc
    21121 tgggtgctgg tcgtgcagtt aagtctgatg ccttggacta tgaaacagga attgtttttg
    21181 aaaagaagat tggagactcc gttcaaaagg gtgaaattgt tgcaaaagta tacacaaatg
    21241 aaaaaattcc acctcaacta gttacagatt tccaaaaatg tgttaaaata agtgatgaag
    21301 tgaaaaaaat ccgtgaaatt gtagaaatca tctcctaaat ggagggaaaa ccgaaatgaa
    21361 attaaataaa tatatagatc atacgctttt aaaacaagat gcaaagaaaa aacaaattga
    21421 tagtttgttg tctgaggcta gagagtatga ctttgccagt gtttgcgtta atccgacctg
    21481 ggttgaacat gctaaaaaag gacttgaagg cacagatgtt aaggtttgca cagtagtagg
    21541 tttccctttg ggagcaacaa cttcagccgt gaaagcattt gagacaaaag aagctatcca
    21601 aaatggtgca gatgagattg atatggtgat caatgttgga gctctcaaat caggtaattt
    21661 agccttggtt gagtcagata ttcgcgcagt agtggaagca agtggtgata agttagtgaa
    21721 agtcattatt gaagcttgcc ttctgacaga ccaagaaaaa attgttgttt gccaattggc
    21781 ccaaaaagct ggggctgact ttgttaaaac atctactggt ttttcaactg gtggtgctac
    21841 gatagcagat gttacattaa tgcgtgaaac agttggatct gatatgggag tcaaggctgc
    21901 tggtggagct cgttcttatg cagatgctct tgcctttgtc gaagcaggtg cgacccgtat
    21961 cggaacgtca gctggggtag ctattttaaa aggagaattg gcagatggcg actactgagt
    22021 tgattgaact ggcaattgaa accagcaaac atgcctatgt cccctattct cactttccta
    22081 tcggagcagt tttagtagcc aaagacggaa gtgtttacac gggagtgaat atcgaaaatg
    22141 ctagctatcc tttgaccaat tgcggtgaga gaacagctgt ttttaaggct atatctgaag
    22201 gccaaagaga attttcagaa ttgattgtct atggtcaaac tgaaaaaccg atctcgccat
    22261 gtggtgcttg tcgccaagta atggtcgaat tttttgaaca agatttaaaa gtgaccttag
    22321 tcgcaaaaga taaatcgacg gtcgagatga cggtcgggga attacttcca tactctttta
    22381 cagacttaaa ctagtctgag tcgctctctg agtggcacgg tccttgtggc caaccaatcc
    22441 atacttgcaa catcgttgca catcttattt aggaggttca gtaatgaaca agaaacaatg
    22501 gctaggtctt ggcctagttg cagtggcagc agttggactt gctgcatgtg gtaaccgctc
    22561 ttctcgtaac gcagcttcat cttctgatgt gaagacaaaa gcagcaatcg tcactgatac
    22621 tggtggtgtt gatgacaaat cattcaacca atcagcttgg gaaggtttgc aggcttgggg
    22681 taaagaacac aatctttcaa aagataacgg tttcacttac ttccaatcaa caagtgaagc
    22741 tgactacgct aacaacttgc aacaagcggc tggaagttac aacctaatct tcggtgttgg
    22801 ttttgccctt cacaatgcag ttgaagaagc agctaaagaa cacactgact tgaactatgt
    22861 cttgattgat gatgtgatta aagaccaaaa gaatgttgcg agcgtaactt tcgctgataa
    22921 tgagtcaggt taccttgcag gtgtggctgc agcaaaaaca actaagacaa aacaagttgg
    22981 ttttgtaggt ggtatcgaat ctgaagttat ctctcgtttt gaagcaggat tcaaggctgg
    23041 tgttgcgtca gtagacccat ctatcaaagt ccaagttgac tacgctggtt catttggtga
    23101 tgcggctaaa ggtaaaacaa ttgcagccgc acaatacgca gccggtgcag atattgttta
    23161 ccaagtagct ggtggtacag gtgcaggtgt ctttgcagag gcaaaatctc tcaacgaaag
    23221 ccgtcctgaa aatgaaaaag tttgggttat cggtgttgat cgtgaccaag aagcagaagg
    23281 taaatacact tctaaagatg gcaaagaatc aaactttgtt cttgtatcta ctttgaaaca
    23341 agttggtaca actgtaaaag atatttctaa caaggcagaa aaaggagaat tccctggcgg
    23401 tcaagtgatc gtttactcat tgaaggataa aggggttgac ttggcagtaa caaacctttc
    23461 agaagaaggt aaaaaagctg tcgaagatgc aaaagctaaa atccttgatg gaagcgtaaa
    23521 agttcctgaa aaataatgga tggaagtcat ttcttaggaa gcggccaagg gccgcttttt
    23581 taagagttga gacaaagtca ttttgtctca gtaaagcttg ctactagaca aactagcaag
    23641 ttttattgaa ataaaataag actctgaaag gaagagcaca tggcacacga aaatgtcatt
    23701 gagatgcgtg atattaccaa ggtgtttggt ggatttgttg ccaacgacaa aatcaacttg
    23761 cacctacgaa aaggtgaaat tcatgcactt ttaggagaaa atggggctgg taagtccacg
    23821 ctaatgaaca tgttagcagg ccttcttgaa ccaactagtg gtgaaatcgc ggtcaacggt
    23881 caagttgtca atctcgactc cccatctaaa gcagctagct tgggaatcgg gatggttcac
    23941 cagcacttta tgttggttga agccttcaca gtggctgaaa acatcatttt aggtagtgaa
    24001 ttgactaaaa atggtgtgct agatatcgct ggagctagca aagaaatcaa ggctctttct
    24061 gaacgttatg gcttagctgt tgacccttct gccaaggtag cagatatctc agttggagcc
    24121 caacaacgtg tagaaatttt aaaaacactt tatagggggg ctgatatcct tatctttgac
    24181 gaaccaacgg ctgttttgac tccatcagaa attgatgagt tgatggctat tatgaaaaat
    24241 cttgtcaaag aaggaaaatc aattatcttg attacccaca aattggatga aattcgcgca
    24301 gtttctgacc gtgttacagt tatccgtcgt gggaaatcaa ttgaaaccgt tgaaattgca
    24361 ggggctacca atgctgattt ggcggaaatg atggtaggac gttctgtttc ctttaaaaca
    24421 gagaagcaag cctctaaacc aaaagaagtg gttttgtcta tcaaagattt ggtggtcaat
    24481 gaaaaccgtg gtgttccagc tgttaaaaat ctgtccttgg atgttcgtgc tggagagatt
    24541 gttggtattg cggggattga tggaaatggt cagtctgaac tgattcaagc cattacaggt
    24601 cttcgtaagg ttgaatctgg tagcattgag ctaaaaggag attcaattgt aggcttgcac
    24661 ccacgtcaga ttacagaact aagtgttggg cacgttccag aagaccgtca ccgtgatggc
    24721 ttgattttgg aaatgatgat atctgaaaat attgcccttc aaacctacta taaagaacca
    24781 catagtaaaa atggaatttt gaattattca aatattactt cttatgctaa aaagctgatg
    24841 gaagagtttg atgttcgcgc tgccagtgaa ttagttcctg cagctgcact ctcaggagga
    24901 aatcaacaaa aagcaattat tgctcgtgaa attgatcgag atcctgatct ccttatcgtt
    24961 agccagccaa ctcgtgggtt ggatgtcggt gccattgagt atatccacaa acgcttgatt
    25021 gaagagcgtg ataatggcaa ggctgtcctt gttgtcagct ttgaattgga tgagatttta
    25081 aacgtctcag accgtattgc cgttatccac gatggtaaga ttcaaggtat tgtatcacca
    25141 gaaacaacca ataaacaaga acttggtgtc ttgatggctg gtggaaactt gggaaaggag
    25201 aagagtgatg tctaaaaaat tacaacaaat ttcggttccc ttgatttctg tatttctagg
    25261 aattttactc ggagccattg tcatgtggat cttcggttat gatgctattt ggggctacga
    25321 agaattgttc tatacagcct ttggcagtct gcgtgggatt ggagaaatct tccgtgctat
    25381 gggtcctctg gtcttgattg gtcttggttt tgcggttgcc agtcgagctg gtttctttaa
    25441 cgtcggactt cctggtcagg ctttggcagg ttggattctc agtggttggt ttgcgctgcc
    25501 gcatccagat atgccccgtc ccttgatgat tctagcaacc atcgtgattg ccttgattgc
    25561 tggtgggatt gtcggagcga ttccaggtat tcttagggcc tatctaggga cgtcagaggt
    25621 tattgtaacc atcatgatga actacattgt cttgtatgta gggaatgcct ttatccatgc
    25681 tttccctaaa gaattcatgc aaagtacaga ttcgaccatt cgtgttgggg ctaatgcaac
    25741 ctatcagaca ccttggttgg ctgagttgac tggtaactca cggatgaata ttggtatttt
    25801 ctttgccatc attgccgttg cagttatttg gttcatgctc aagaaaacaa ctcttggttt
    25861 tgaaatccgt gcagttggtc ttaatccaca tgcttcagaa tatgctggta tttctgccaa
    25921 gcggactatt atcctatcta tgattatttc aggtgccttg gcaggtcttg gtggagctgt
    25981 tgaaggtttg ggaaccttcc agaacgtcta tgttcaaggt tcgtcattag ctatcggatt
    26041 taacggaatg gcggttagtt tgcttgcggc caactcacca attggtatac tctttgcagc
    26101 cttcctattt ggcgttctcc aagttggggc tcctggtatg aatgcggcgc aggtaccatc
    26161 tgagcttgtc agcattgtaa cagcgtctat tatcttcttt gtcagtgttc attaccttat
    26221 cgaacgcttt gtcaaaccga aaaaacaagt taaaggaggt aagtaaagat gtctataata
    26281 accttgctcc ccctcttggt gtcttctatg ctgatttact cagcacctct catctttaca
    26341 agtatcggtg gtgttttctc tgaacgtggt ggtgtggtaa acgttggcct tgaaggaatt
    26401 atggttatgg gtgccttttc tggagttgtc tttaaccttg aatttgcaga acaatttgga
    26461 gcagcaactc catggctatc cttgcttgta gcaggattgg ttggtagtgt tttctctatc
    26521 atccacgcag cagcgacggt tcatttccgt gcagaccatg ttgtcagcgg tacggtattg
    26581 aacttgatgg cgcctgcctt ggctgttttc ttagttaaag ttctttataa caaaggacaa
    26641 accgacaacc taagtcaaac ttttggacgc tttgatttcc cagtcttggc aaatatccca
    26701 gtgattggtg atatcttctt caagtcaact agtctacttg gttatctggc gattgccttc
    26761 tcattccttg cttggtttat tctctttaag actcaatttg gtcttcgtct ccgctctgtc
    26821 ggtgaacatc ctcaagcagc ggataccttg ggaatcaacg tctacaagat gagatattta
    26881 gggattatta tttcaggttt tctaggtgga attggcggag cgatttatgc gcaatcaatc
    26941 tcagttaact tctcagtgac aactattgtt ggacctggat ttatcgccct tgctgcgatg
    27001 atctttggga aatggaatcc aatcggtgct atgctttcta gtctcttctt tggactttca
    27061 caaagtttgg ctgttatcgg ttctcaattg ccgttcctac aaggagtgcc agcggtttat
    27121 cttcaaattg caccttatgt tttgacaatt cttgtcttag cagccttctt tggaaaagca
    27181 gtcgcaccaa aagcagatgg tatcaactac atcaaatcaa aataagcata caaaaaaacg
    27241 tcagtccaat gactgaactg ccccccaaaa gttagacaga aaaaatctaa cttttggggt
    27301 gtttttatta tgaaattgag ttgtgatgat aaagttcaga tctatgaact tagaaaacaa
    27361 ggatatagct tagagaagct ttcaaataaa tttgggataa acaattctaa tcttaggtat
    27421 atgattaaat tgattgatcg ttacggaata gagttcgtca aaaaagggaa aaatcgttac
    27481 tattct
//
LOCUS       DAVMJI010000028        26077 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.028, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000028 DAVMJI010000000
VERSION     DAVMJI010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26077
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.028"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..775
                     /locus_tag="VYR58_001466"
     CDS             <1..775
                     /locus_tag="VYR58_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV3622599.1"
                     /translation="NTIFTEYSSTTNIDQILVERKRDGNSKTIYKVDNNGNYILAKEK
                     NGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQIIKIATDKNDIVLDPFCGSGTTL
                     VASKILNRNYMGIDLSEEAINITQQRLENVIKTSSNLLNKGIEAYRTKTEEEENILKL
                     LQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNECLNESISLLQNAINSKKLDFGVVI
                     KTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKSQQLL"
     gene            complement(851..2413)
                     /gene="guaA"
                     /locus_tag="VYR58_001467"
     CDS             complement(851..2413)
                     /gene="guaA"
                     /locus_tag="VYR58_001467"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV3622600.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2555..3253
                     /locus_tag="VYR58_001468"
     CDS             2555..3253
                     /locus_tag="VYR58_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV3622601.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3296..4192)
                     /locus_tag="VYR58_001469"
     CDS             complement(3296..4192)
                     /locus_tag="VYR58_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV3622602.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLSYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQANIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4201..5136)
                     /locus_tag="VYR58_001470"
     CDS             complement(4201..5136)
                     /locus_tag="VYR58_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV3622603.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYSGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQTFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5133..5858)
                     /locus_tag="VYR58_001471"
     CDS             complement(5133..5858)
                     /locus_tag="VYR58_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV3622604.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5942..6577)
                     /locus_tag="VYR58_001472"
     CDS             complement(5942..6577)
                     /locus_tag="VYR58_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV3622605.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKMIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQDL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(6579..7406)
                     /locus_tag="VYR58_001473"
     CDS             complement(6579..7406)
                     /locus_tag="VYR58_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV3622606.1"
                     /translation="MMIKIIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7428..7763)
                     /locus_tag="VYR58_001474"
     CDS             complement(7428..7763)
                     /locus_tag="VYR58_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV3622607.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEGGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7764..8480)
                     /locus_tag="VYR58_001475"
     CDS             complement(7764..8480)
                     /locus_tag="VYR58_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV3622608.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEQRDQAPLVIKEVNGIKVALLAYSYGFNGIEQYISQEDYNRYLLD
                     LNEDKMKAEVERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIIY"
     gene            8993..9604
                     /locus_tag="VYR58_001476"
     CDS             8993..9604
                     /locus_tag="VYR58_001476"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV3622609.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9649..10377
                     /gene="rlmB"
                     /locus_tag="VYR58_001477"
     CDS             9649..10377
                     /gene="rlmB"
                     /locus_tag="VYR58_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV3622610.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKNEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10416..11327)
                     /gene="trxB"
                     /locus_tag="VYR58_001478"
     CDS             complement(10416..11327)
                     /gene="trxB"
                     /locus_tag="VYR58_001478"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV3622611.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLGDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11393..11617)
                     /locus_tag="VYR58_001479"
     CDS             complement(11393..11617)
                     /locus_tag="VYR58_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV3622612.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11695..12438)
                     /locus_tag="VYR58_001480"
     CDS             complement(11695..12438)
                     /locus_tag="VYR58_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV3622613.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12438..13238)
                     /locus_tag="VYR58_001481"
     CDS             complement(12438..13238)
                     /locus_tag="VYR58_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV3622614.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13396..13752)
                     /locus_tag="VYR58_001482"
     CDS             complement(13396..13752)
                     /locus_tag="VYR58_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV3622615.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13746..14276)
                     /locus_tag="VYR58_001483"
     CDS             complement(13746..14276)
                     /locus_tag="VYR58_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV3622616.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(14276..14770)
                     /locus_tag="VYR58_001484"
     CDS             complement(14276..14770)
                     /locus_tag="VYR58_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622617.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14905..15351
                     /locus_tag="VYR58_001485"
     CDS             14905..15351
                     /locus_tag="VYR58_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV3622618.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15348..15995
                     /locus_tag="VYR58_001486"
     CDS             15348..15995
                     /locus_tag="VYR58_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV3622619.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(16016..16597)
                     /gene="pdxT"
                     /locus_tag="VYR58_001487"
     CDS             complement(16016..16597)
                     /gene="pdxT"
                     /locus_tag="VYR58_001487"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV3622620.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16598..17473)
                     /gene="pdxS"
                     /locus_tag="VYR58_001488"
     CDS             complement(16598..17473)
                     /gene="pdxS"
                     /locus_tag="VYR58_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV3622621.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17625..19004)
                     /locus_tag="VYR58_001489"
     CDS             complement(17625..19004)
                     /locus_tag="VYR58_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV3622622.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19298..20221
                     /locus_tag="VYR58_001490"
     CDS             19298..20221
                     /locus_tag="VYR58_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV3622623.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVINKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            20281..20886
                     /locus_tag="VYR58_001491"
     CDS             20281..20886
                     /locus_tag="VYR58_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV3622624.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFSDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20905..22149
                     /locus_tag="VYR58_001492"
     CDS             20905..22149
                     /locus_tag="VYR58_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV3622625.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22372..22629)
                     /locus_tag="VYR58_001493"
     CDS             complement(22372..22629)
                     /locus_tag="VYR58_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV3622626.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22671..24707)
                     /locus_tag="VYR58_001494"
     CDS             complement(22671..24707)
                     /locus_tag="VYR58_001494"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV3622627.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24919..25836)
                     /gene="glyQ"
                     /locus_tag="VYR58_001495"
     CDS             complement(24919..25836)
                     /gene="glyQ"
                     /locus_tag="VYR58_001495"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV3622628.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
BASE COUNT         7793 a         5794 c         4708 g         7782 t
ORIGIN      
        1 taatacaatt tttacagagt attcttctac tacaaatatc gaccaaatac tagtggaacg
       61 aaaacgagat ggaaactcta aaactatata taaagttgat aataatggta actatattct
      121 agcaaaagag aaaaatggag ttcccctttc agatgtttgg aatataccat ttcttaatcc
      181 aaaagctaaa gaaagagtag gttatcctac acaaaaacct attctgttat tagaacaaat
      241 tataaagatt gctactgata aaaatgatat agttttagac ccgttctgtg gaagtggaac
      301 tactttagta gcctccaaga ttttgaatag aaattatatg gggattgatt tatctgagga
      361 agctatcaat ataactcagc aacgtctgga aaatgttata aaaacaagtt caaatttatt
      421 gaataaagga atcgaagcat atagaaccaa aactgaggaa gaggaaaaca ttcttaaatt
      481 attacaggca aaaattgttc aaagaaataa aggaattgat ggttttttac ctaaacattt
      541 tcaaaaaaaa ccgataccta taaaaattca aaaaaataat gaatgtctga atgagagtat
      601 ctctttatta cagaatgcta taaactccaa aaaacttgat tttggagtag ttataaaaac
      661 tcattcagat aatttattat ttgattttga tacgattcct gaaaatataa tagtagttga
      721 ccattttgaa cttacaatcg aaaaatggtt aagtaaaagt caacagttac tatagtttgc
      781 aaattattta cagaaagaac aaaaaatgct ctgaaacact gatttcaaag cattttttgt
      841 tagtttaaaa ttactcccac tcaactgttg caggtggttt acttgtaata tcgtagacga
      901 tacggttaac atgatccact tcatttacga tacgtactga gattttttga agtacttccc
      961 atggaatttt ggcaaaatca gcagtcatac catcgataga agtgatagca cggattgcaa
     1021 tcgtgtagtc atacgtacga ccgtcaccca taacaccgac tgaacgaacg cctgtgttaa
     1081 cagtgaagta ttgccaaata tcgcggtcaa gtccagcttt agcgatttct tcacgaagaa
     1141 tagcgtctga ttcacgaacg gtttcaagtt tctcttcagt gatttcaccc atgacacgga
     1201 tagcaagtcc tggtcctggg aatggttggc gccatacgat atggtctggc ataccaagct
     1261 ctgtaccaag agcacgaact tcatccttgt aaagagtatt aagtggttca atcaattcaa
     1321 actgcatatc ttctggaaga ccacccacgt tgtggtgtga cttgatagtt tgagctgtat
     1381 ccgtaccaga ctcgataaca tctgtgtata aagtaccttg agcaaggaat ttcacatctt
     1441 tgagcttgct tgcttcgtca tcgaatacat agacaaactc gttaccgatg attttacgtt
     1501 tttgttcagg atcagaaacg ccagcaagtt tgtcaaggaa acgtttagca gcgtctgctt
     1561 tgacgatatt caaaccaaac ttaccaccga gcatgtccat aacttgatca gcttcgcctt
     1621 tacgaagaag accgtggtct acgaagatac agatcaattg atcgccaatc gctttttgga
     1681 gaagaacccc aacgacagat gagtcaacac cacctgatag accaagaagg acacgtttat
     1741 caccgacggt ttcacgaatt tttttgatct gcatgtcaat gaaattatcc attgaccagt
     1801 cacctttagc cttacaaatg ttaagggcaa agttacgaag gatatcattt ccgtatacag
     1861 aatgacgaac ttctgggtgg aattggatac cgtaaatgtg tttatctggg ttttcgatgg
     1921 ctgcgtatgg gcagtcagct gatgtacctg tacgaacaaa gtcagcagga atctcagtaa
     1981 ccgcatcacc atggctcatc aaaacagtct gttcatcagg tgttgattca aaaagcgctg
     2041 atggtgtgtg agttagggtt gattgaccgt attcacgatt tccagcatca cctgcaggaa
     2101 caacttttcc tccaagttta tgggtcaata actgcatacc ataacagatt cccaaaattg
     2161 gaattccgag ttcgaagatt tctgggtcaa tatcaaatga accatcttca tatacagaat
     2221 ttggaccacc tgatagaata attcctacag gattgacttc acgaacttca gcagctgaaa
     2281 ttttatggct ttttagttct gaaaaaacac caatctcacg gatacggcgt gaaatcagct
     2341 ggttgtactg gctaccatag tccaatacga tgattttttc tacatcttgc aaatcagttg
     2401 aaatgttgct catctttttc ctttctcaaa agaaatatct tttctcaata ttctatcaca
     2461 aataagggcg aattaccaac taaacaaggc gaagtttgac tttttctagt ttattggggt
     2521 acaatagaga aaagatagaa atgaagtgaa aaatatgcta cctgcttata tgaaaatcca
     2581 tgatcagata aaaaaggata ttgacgagca ccgttgggct attggtgaga ggcttcccag
     2641 tgaaagagat ttagctgagc agtttgcggt cagtcgcatg accctccgcc aagccgtatc
     2701 tctattagtc gaagaaggcg tcttagagcg ccgtgtagga agcggcacct ttgtttccag
     2761 tactcgagta caagaaaaga tgcgagggac aaccagtttt actgaaattg tcaaatccca
     2821 aggtaaagtt ccctctagcc agctcatttc ctacaaaaaa accattccca atgagcaaga
     2881 agttgccaag ctaggaattt ttccaacgga caatattatc cgaatggagc gggtccgcta
     2941 tgccgaccaa gttcccctag tttatgaagt tgcttctatt cctgaaaaat tcattaagga
     3001 ctttaaaaaa gaagaaatca ccagtcattt cttccaaacc ttgcagaaac atggctatcg
     3061 tatcggcaaa tctcaacaga ccatctatgc tcgccttgct aaagaaaaga ttgcccacta
     3121 tttggaagtt gaaaaaggac atgctattct tggattgaca caggtttcct acctagaaga
     3181 tggtactgct tttgaatacg taaaaagtca atatgtaggc gaacgctttg aattttatct
     3241 tgaaaataat tagattacca cgcaaaaact ctctgtcaca gacaaagagt cttttttatt
     3301 tttctaagaa taaatctttc aaagaaatca aagttacagc aaacaatatc attgccatac
     3361 caagaaaatc aatgggataa aattgttcat tcattattaa gaaggcaaag aaaaccgccg
     3421 atattggctc aattgaagcc aacaagcttg acttgaccgg tcctatcaga ctggctcctt
     3481 taaggaaagc tgtataggca aagacagtcc cgataaggat aatgcctgca aacgcaagga
     3541 gaaaatcaag actagtcggg atattggcct gtagaacccc tgtaaaagga agggcgacca
     3601 aacctgctat aaccattccc acaccaatga ccaagctact cccccacttt ttaatcaagg
     3661 ctatgggtaa aatgatatat agagcataag tcaaggcaga aaagagaccc cagaacaggc
     3721 cagcaggtgt catggataac tggtccaact gcccatgtgt tgcgatcagg aaggttcctc
     3781 cgatggcgaa tatgatggaa actatctctc ccagtgtcgg tgccacccta tccttgatac
     3841 agctataaat taaaattccg acaggacaaa catactgaag caccgtcgct gttcccgcat
     3901 tggtctcctg aatagcagac agataggcga attggttgag aaaaagacca atcagagcaa
     3961 aaataagaag agacagcaaa ctctttctat cctttaaaaa gaccagtatt ttatcctttg
     4021 cagtagcata agacaagagc atgagaattc caccagcgat taaaagacgc aagttggtca
     4081 agaccagagc cgaaattccg tgtgccatta ggtattggcc actcgttcct gacaaccccc
     4141 aagcaatacc agccacaact gttagtaaag tcccttttaa actatttgac atgtctctcc
     4201 ttactcttct ttgcgaatca agttcatcac ttgattgcgg tctaatatcc attgagctct
     4261 ctcgtccttt tcataggtac gattcgatag gaaaatagtg gcttcttgct tctgacgatt
     4321 ccacatgata aaggtacctg tatagcccgt atggtctagc caatctcctt ccaaattcca
     4381 tgctaaagaa cgttccttgt catccaaagg agaaaaattt tgatttaagt ctcttgcaaa
     4441 atcatctgct aaatagtgtt ctaaaaaggt ttgtaaatcc tttatagtcg aaaataaacc
     4501 agcactccca gcatgtctac ccaggagacg agccttggga tcatgcacta tgcctgcctc
     4561 tacacctcta actgttggaa cagcaagctc aactggccca aacttagttt ccgtcattcc
     4621 ccaaggtttc cagacttgat cctttaaaat cacatccaaa tcttgattaa aaattctttc
     4681 caaaataaag cccaacagca aaaaatggac atccgaataa agaaaggctg gctgacttcg
     4741 tctgttgaga tgaaacatcg cttcctttaa ttcaggggct gttaaaagat cacgattagg
     4801 aataaaagga tcaaggtctg ttgcatgagt caagagctgg cgaatagtga tgtctggata
     4861 atcactctca ggtaaaaaat ctattaccag tctatcaata tctaattgac ctatttccca
     4921 caagaaggta caaactgtgc caaccccaac aaccttactg acactagcta ggtcataaac
     4981 tagtcctgcc tcagtctgca agccatgctc tgggtcactc tggcctgaat agaactctgt
     5041 ccattgattg tccttaaaat acgcaaaaga ggctccggga taaatccctg cctcgatttg
     5101 ttcttctatt tttttaataa tcttggtcca cttcatactt cttcaaacca caattcaaca
     5161 ttatttctat ctttaccaag gaagaatttt tcagacttag gaataaaata ttcagtagac
     5221 tcaaacttct ggcgaagact tgctatgtct aattcattga ccaagaactt gagcatagat
     5281 aagtcccagg taaccgtatt gtccacagtc aaatcctgcc cctgagctgg aataaaatca
     5341 agggatgccc caatttcaga tgattccaag aaactttcga tatcagttgg gagatgtaat
     5401 tccatagaaa tctcaaattt acttaaagaa attgatgcca aatctgtttg aaattcaggc
     5461 ttttctccta cttctactag acttgctctg tcatcttccg catgaatcaa aatcaaatca
     5521 tcttctggtg agaaaatttc aaaagcgtag ccattttgac ctttatataa tcgatgaatc
     5581 gaatctgttt tagataagat tccttcaatt tctaagggat tttccacctt gacaatcaat
     5641 ctagctagtt tttttcttcc ctctacctta cgagtacgca tactgggagc ttcttctaaa
     5701 accagctttt caagacccgt ttggtcacct agtgacagaa aggccgattc ttctaacaag
     5761 gccttcattc caagggtttc aatataaaat gtttcattta attttctatt attagctttt
     5821 aaagtaggaa taatccgtac aatctgattt acattcataa attcctccgt cactttttat
     5881 tttaaaggat tttagaattt tttacaagat attatgctca aatttcacat tatttagcta
     5941 tttagtaaag atagtctttc aaggcttttg acaaagcctg ataaccagca atactgaggt
     6001 gcagtccatc agttgtatat tcttttttga gttggcctgc ttggtctgtc aaacaatcaa
     6061 atactggcac aaattccacc tgcatatagg cagatgcaag atcttgatag gcttgattcc
     6121 agttctgaat tttttcattc gagcggatat agactgcctg ctgatactcc tctccctcat
     6181 tgacaggtaa aatggaaagc aatttaatct ctgtcaatgg ataatcgcga gcaacggatt
     6241 gaatgatagc ttcgagatta ttgagagcct cattcacagg aacatccttt ccgatatcat
     6301 ttgtcccaat cagaagaaaa attttatcta ctgctccacc atatagatga gcatcaaggt
     6361 tctctagtaa cagtcctgtc tgatagccac gaattcctcg attgacaatc atttttgaag
     6421 tcccaaatag ctcctgtaga ggataatact cgacaatgga atccccaata aaaagaatgt
     6481 ttggttctac aacagaaatg tgatttaggt gacgatactt ggtttgaatt ttttcttgtt
     6541 cctttaggag ccaattttct aataactgta ctgccacttc attctccttt ttctaaccag
     6601 ttttccaaga cttgataaac tcctccttgg ctattggctg gtgctagagc agtcgccaca
     6661 gctttggctt tctcatcagc attttccatc gcataggcaa ttccagccat ttcaagcatt
     6721 tcaacatcat tttcactatc accaaaagcc atgatttctt gggatttcaa gtcccagcgc
     6781 ttgagtaatt cctccaagcc ccatgcttta tgaatcccag cttggaggat atcaatgcaa
     6841 ccatagccac tggatacagc tcggacacgg ccatcaaaga gagcattgat ttcttccaaa
     6901 accgaactca aacgttcctc accaacaacc atgctcatct tgagcacacc accaaagagg
     6961 tcagatgtta attcatccac aaattgcatc cgttggtaga atttttcaat catttctgga
     7021 gtcataaaac tttcaagatc tgtaaaaatc gtaccttcct tgacaaaatc acccttcatc
     7081 cccgttacaa caaactggtc ctgacacgct cgacccttga aatgagccaa agccttgttg
     7141 acaatggcgt catcccatgt ctgagcctga atcaattcat tgttttcaaa aatacgagcg
     7201 ccattagcaa caaccagaac cactcgatcc accaagggac tcagtagttg tctcatgcgg
     7261 tgaatttcat tgcccgtcgc aatgacaaaa cgaatgcccc tttgatccaa ctgatctaaa
     7321 atcttttcca atcgtgggag atcaagctga cctctagcat ccagcaaggt cccatccata
     7381 tctgtcgcaa ttatcttaat catcatttac tttcctctgg attcaagcta ataccacttc
     7441 aatcccacat gttcattcat ttctttatag gctgtatcaa ttcgttcctt agtcgcttca
     7501 tctaactggt cacgatgact gccaccctct ataaaatctt ccaaaatata agtttggtaa
     7561 tgatacaagg gatatccttc tggtgaaaag gttccctttg gtgttcgatt gacccaagta
     7621 ggatgagctt tagctgttcc gatagttgtt tttccatcct tcttcttgat ggtgacatcc
     7681 atgagaacac cacgttcagt ccacttagca ttctcttcat ctcccataga ttcaatccgt
     7741 tgattggaaa tgaagttccc catttaatag ataatgagtt tcttatctcc atctttttca
     7801 accgtttcag atggttcaac aacgtgagga tgccctccaa agataatatc cgctccccaa
     7861 tcgatcatct tgtgataaag agctttttgt tcttcagttg gttccaatcg atactcaaca
     7921 cccatctgaa gcatgataat ggtgatatct gcttccttct ctgcccgttc aacttcagcc
     7981 ttcatcttat cttcgtttaa atctaaaaga taacgattat agtcttcctg agaaatatac
     8041 tgctcaattc cattgaaacc ataggaatag gctaacaatg caaccttgat accattcact
     8101 tccttaatga ccagcggagc ctgatcacgt tgttcgtgcg tataaactcc gattggagtg
     8161 attccagctt tctcaataat atcggccgtt gaaataactc cctcaatttg cgaatccaaa
     8221 atatgattat gagctaaatc cagcacatga taacctgctt ccttaatagc atccataact
     8281 tcagcaggag cattaaagag aagataaccc gctaaataat gatccttatt aatggttcct
     8341 tcgaaatcac caatagctaa atctgcttgc ttgagccaag gagtcacata ctcaaaattt
     8401 tcatgaaagt cataggtacc gtcttctttt ttagctgaaa agaaaagtcc atcgtggtag
     8461 agcaaatccc cgtgggccat aattctggca gttttttcct cttcctactc ctgagacttt
     8521 tgcttagtcc cctcttgaga aatagtatct cgtttttgac tagtcaaggg attccttgga
     8581 agctttcaaa caacaagacc aagcccattg ataaaccaac tgctagcaag agtatcgcca
     8641 caaatccctt attgctccac ttgcgataac tcctaaaaag tttaccaagc ccttcataaa
     8701 acgaaaagct aaaccaccct gatttcgatt ttgtcttctt tgtatcttcg ttctccctac
     8761 tttcttatgc aagccttttc tttttattat atcacagata agtatttctt tcacaattga
     8821 attgaacttc ctatctattt tctataaatc ctaaatgcca taatgctttc aattcttgtc
     8881 attttgtgat atcatgtaga ggaaatgaac taatccacag tggcttattc caagtatacc
     8941 acttgggctt tggcagtagc taactgcact aaacataata taaggagaga aaatgtctgc
     9001 aatagaacgt attacaaaag ctgctcactt aattgatatg aacgatatta tccgtgaagg
     9061 gaatcctact ctacgcgcga ttgctgagga agtcactttc cccctatctg accaggaaat
     9121 catcctaggc gaaaagatga tgcaattcct taaacattcc caagatcctg tcatggctga
     9181 aaaaatggga ctccgcggtg gtgttggact ggctgctccc cagttagata tctcaaaacg
     9241 cattatcgct gttttggtac ctaatattgt tgaagaaggc gaaactccac aggaagccta
     9301 cgatttggaa gccattatgt acaatccaaa aatcgtctct cactctgttc aagatgctgc
     9361 tcttggcgaa ggagaaggtt gcctgtctgt tgaccgtaac gtgcctggct atgttgttcg
     9421 ccatgcccgc gttactgttg actactttga caaagatgga gaaaaacacc gtatcaaact
     9481 caaaggctac aactccattg ttgttcagca tgaaattgac cacattaacg gtatcatgtt
     9541 ttacgatcgc atcaatgaaa aagacccatt tgcagttaaa gatggtttac tgattcttga
     9601 ataaagaaaa tcccgttgca agacggggtt ttgtgttata atagaggcat gaaaacaaat
     9661 gatattgtct atggcgtcca cgccgttacc gaagccctcc ttgcaaatac aggaaacaaa
     9721 ctctacctcc aagaagatct ccgaggtaag aatgttgaga aagtcaagga actagctaca
     9781 gaaaagaagg tgtccatttc ttggacatca aaaaaatctc tctctgagat tactgaaggt
     9841 gctgttcatc aaggttttgt tctacgagtg tctgaatttg cctatagcga gctagattac
     9901 atccttgcaa aaacacgcca agaagaaaat ccacttctat tgattctaga tggtctaacc
     9961 gatccccata atctaggttc tatcttgcga acagccgatg cgaccaatgt ttcaggtgtc
    10021 atcattccca agcaccgtgc tgtcggagta actcctgtcg ttgccaaaac agccacaggt
    10081 gctattgaac acgttccaat tgcccgagtg accaacctca gtcaaacctt agataaactt
    10141 aagaatgaag gtttctggac ctttggaacg gatatgaacg gtactccttg ccacaagtgg
    10201 aatacaaaag ggaaaatcgc cctcatcatt ggaaatgaag gaaaaggtat ctctagcaac
    10261 ataaaaaaac aggtcgatga aatgattacc attccgatga atggacatgt tcaaagcctt
    10321 aatgccagtg ttgctgcggc cattctcatg tacgaagttt tccgaaatag actataaaaa
    10381 agtttccagt catctgattg gaaacttttt tatgattaac tatgttctgt aatgaattta
    10441 taggcttctt gaccagcgat agctccatct ccaaccgctg ttgttacttg gcgaaggtct
    10501 ttcaagcgaa catctccaac tgcaaagata ccgtcgactg cagttttcat gtggttatct
    10561 gtcacaatcc atcctgcctg atcttggata ttcaattctt taacaaaatc gccaagaggg
    10621 tccaatccaa catagataaa gacaccaccg aagacttgtt ctgtcacttg acctgttttc
    10681 acattttcaa atacgactga ttctactcgg ttttcaccct tgatttccct tactacagaa
    10741 tcccagataa agctgatttt ttcattcgca aaggcgcgat cttgtaaaac cttttgggca
    10801 cgaagttggt cacgacggtg aacaatggta acagtcttag caaaacgagt caagaagagg
    10861 gcttcttcaa cagctgaatc tccaccacca actaccaata aatcttggtc acggaagaaa
    10921 gcaccatcac acacagcaca gtaagaaaca ccacgactgt tcagttcttc ttctccaggt
    10981 actcccaaag gacggtgttt agaaccagtt gctacgataa ctgtacgtgt ttcatatgtt
    11041 tggtcatcag tcatcacttt cttaaaatca ccatggtctt cgacattttc aacataacca
    11101 taaatgtgct ccacaccaag attttcaagt ggttcaaaca tcttttcagc caattcaggt
    11161 ccactaatat tagcgtatcc tgggtaattt tcgatatcag atgtattatt catctgacca
    11221 cctggcagac caccttcaat caaagctact tttagattgc ttcgagcagc atacaaggcc
    11281 gcagtcatcc ctgcaggtcc agcaccgata ataatagtat cgtacatata gattccttct
    11341 ttcttgttgt aactatcttt attctaactc tttcttgtca atcacgcaag gattatgcct
    11401 tgaaaacaag aattaaactc ataaccgcaa aggataatac tgggacaacc aagactccaa
    11461 tcataatcat atcatagaga tgggcttggc gagccctggc tgtcttatca actcccgaca
    11521 tggctctcag accaatccaa atccctaaaa aaatcagaac aaggatggtg gtcaagatca
    11581 aactctcgaa atataaagaa aatagttgca gtagcatgat ttctctcatt tctatctttt
    11641 ttaaagagta aactcagcta gtccaactaa ctgagttttc ctttatctat tatatcaaat
    11701 ataagtccgt ttgtaactag cgaagaattc ttttgtccgc tcttctttag gggtgtggat
    11761 aatctcatcc ggtgttccag actcgatgat tttcccctta tctaagaaga gaatcttatc
    11821 agccacttgg gctacaaagg acatgtcatg actaaccaaa atcatggttt gacctgactt
    11881 agcagcatct gcaatagact tttctacttc accaaccaat tctgggtcaa gggctgaagt
    11941 tggttcgtct aagagcaaaa catctggttt catagcaagc gcacgcgcta gggcaacccg
    12001 ttgcttctgt ccacctgata aatggcgagg ataatggttt tcacggtccg aaagcccaac
    12061 cttagccaac tcttccttgg caatcttagt cgcttcttgg tcagataatt tcttgacaac
    12121 aaccaagcct tctttcacat tatcaagtgc tgttcggcgt tcaaacaaat taaactgttg
    12181 gaaaaccata gacaacttac gacgtagggc aaggatttct tcttgagtga ttttagaaaa
    12241 atcaactgaa aaaccatcaa tctgaataga gccactgtca ggtgtttcaa gataattgag
    12301 actgcgaaga aaggttgatt ttccagctcc tgaagaacca atcaaggcta caacttcccc
    12361 tttttgaata tccaagtcca gatgatccaa gacagtctgt cctgaaaagg atttgcttaa
    12421 atttgaaatc ttaatcatta acgaaggtct cctttcacat ctgtttgcac tgtatcaggt
    12481 gcagaaatag ccatttttct ctcgatgaaa cgaccgaggc tttcaattcc gatattgacc
    12541 acccaataaa caagggcaac ggagatgaag cgttcaaaat agcgataatc agctccacct
    12601 agaatctgag cttgggcaaa gacttccaca acacccgcac taaaagctag agatgttccc
    12661 ttggtcaaac cgatgaggga attaatcaag gttggagtag ctaccaccgc tgcattagga
    12721 ataatcactc gtcgataaac ttgcgctcgg gtcataccca gactgcgtgc cgcctcaatc
    12781 tcaccaggat taactgagag aatggctgca cgaatggttt cactagcata agctgcctca
    12841 ttaaaggcaa aggcgacaat cgcaaaagct gcagctggaa tcgcattgat attgagacca
    12901 gttccccatt gctgattgag ggctttcaaa gccaaaggga ttccgtagta ggtcaacatg
    12961 agttgcacca aaatcggtgt cccttttaag aaactaacaa agaaggcctg caagggatat
    13021 aaaatcttga cacgattgat cttcacaatg gcaaaaagaa gcgccaaaac caagccaaaa
    13081 agggcaccac caattgtcaa cataattgtt gttggaagtt gttggacaat tctagggatt
    13141 ccatcaaaga ccgaacgtag gctaaacagc ttgccatccg gaatcaattg catcaagttt
    13201 tggtaccaat ctgatgctaa aatcgttgta acattcataa aaacatcctc ttctgataat
    13261 gattcattct accatgcttc tgccgtcaat gaaattattt gctacggtca gatacagact
    13321 ttgtctacct actagtttat catactttga aacagggaag ttatatattt tatctatcaa
    13381 agagatagat aaaaactatt tcagtcccag ttcttcataa gattttcgat aaccgatttg
    13441 cttaacagtt ccattttcta ctaaaatagg ccgttttaac aacataccgt cacttgctag
    13501 caactcagcc gcttcttggt ttgacaaact tcctacctta tcttttagcc ctaattcacg
    13561 gtatttgata ccactggtgt tgaaaaattg cttcaattca aatcctgagg tttctagcca
    13621 attcaaaatg acttcttggc taggtgtttc ttccacgata tggacggctt tatagtccac
    13681 acctaattga tttaattctt gttttgcttt tttacaagtt gaacatttgg ggtattcgat
    13741 aaattctaac atgtgcttct ccttctattg tttctatctt taaaatctac tccttcatgc
    13801 tccaagagcc aagctttctt ttccactcct gcagcataac ctgtcagacg cttgcctgct
    13861 cccaacacac gatgacaagg tactaggata gaccaaggat tgcgtcccac tgctccacca
    13921 attgcttgag cagaagccac ttgcaggtct tgagcaattt gtccataggt cactgtctga
    13981 ccataaggaa tgccctgtaa atagtcccaa actctctttt caaaattcgt tccgattggc
    14041 gccaagagca agttggataa atcctgaggc ttgcctttaa agtaatcatc taagcaagca
    14101 ataactgggt ctaaaatagg atgactaaca acttcttcta tcgtttcatc tcctagtccc
    14161 ctctcaaaat gcttctgctc ctgaacccaa attccataca aataatggtc atcagctaca
    14221 agtgatagaa taccaattgg tgaggagtag aggattttta catacttctt ttgcattatt
    14281 tctttaattt ttgataggcc aagcgttcgc catctactgg caccttacca acttgtttaa
    14341 aaccaagttt ttcaaaaata tgttgcataa ccttgttttc agcatgcgta tctgagcgaa
    14401 aatcaagata atcaaaacct tcaatcaagc cctctaagaa ggtttgagca actccttttc
    14461 cctgcacatc tgctgccaca gcaatacggt gaaagactag atactctgac tctccagctt
    14521 gccagtttcc ctcataaata gcttcatagg cctcctctgg actcttggtc acagcagcat
    14581 aggctagcag ttctccctct tccaaggcta cgtaggcttg ccctgagatg atatcatcga
    14641 taataacatc tgcatttgga tagccatttt gccactggtt actaccagca tctgctaaac
    14701 attttttggc atcctctatc acctgcatga tggcatctac ttcatttgga aaagctaaac
    14761 gaatttccat cttttttcct catttctgac tagtttctcc catcatagca taatttaagt
    14821 ctttctacaa gcagttaaaa cttgactttg tatttttgtt attttataat ctagttatca
    14881 aaactatata aaaaggagtt gaaaatgaaa actacctttt cctacccaaa atgggcagaa
    14941 attccaaaca ttaacctcta tctggaccag gttttgctct atgtcaatca ggtctgcgcc
    15001 cctatctctc ctaataaaga caaaggccta acagcatcta tggtcaacaa ttatgtgaaa
    15061 aatggttacc tgacaaagcc tgacaaaaaa aaataccaac gccaacagat tgcccgtttg
    15121 attgctatca caaccctcaa gtctgtattt tctattcaag aaatagccca gacacttaat
    15181 actctacaaa ctcaagcaag ttcagaccaa ctctacgatg cttttgtgga ctacatgaac
    15241 caaggaattg acccagctaa ccctattatc caaaccagct gccaaaccgt taaactctat
    15301 catcaaactc tagacttaat cgatcatact caagaggagg taatccaatg aacactagtc
    15361 ttaaactcag caaacaactc agttttggag aggagattgc taatagcgtg acccatgctg
    15421 tgggtgcagt catcatgctt atcttgctgc ctatttcatc catctatagt tatgaagcac
    15481 acggattttt atcctctatc ggcgtttcca ttttcgtcat cagtctcttt ctcatgttcc
    15541 tatcatccac catttatcac tctatggcct atggttcgac ccacaaatat gttttgcgaa
    15601 tcattgacca ttctatgatt tacgttgcca ttgccggctc atacacgccc gttgtcttga
    15661 ccttgatgaa taactggttt ggctatctga ttattgtcat ccaatgggga acgaccatct
    15721 ttggtattct ctataaaatc tttgctaaaa aggtcaatga gaaatttagc cttgctcttt
    15781 acctgattat gggctggttg gttctggcta tcattcctgc cattatcagt caaacgacac
    15841 ccgttttctg gagtctcatg gtaactggcg ggctctgtta tacagttgga gctggatttt
    15901 atgccaagaa aaaaccttat ttccacatga tttggcatct ctttatccta gctgcgtccg
    15961 cacttcaata catcgctatt gtttattaca tgtaaaaaag ttgagaaatt caatctcaac
    16021 ttttttcttt acacatattg ataaagtact ggtgcaagcg cacatcatca gtcaattctg
    16081 gatgaaaaga acttaccaac atattttttt cttgggctgc aacaatttga ttgttcactg
    16141 ttgctaaaat ttctacaccc tcaccaacac tactgataat cggaccacgg ataaaggtca
    16201 ttggaatctt gccaactccc ttacattctg cttccgtgta gaaacttcct aattggcgcc
    16261 cataagcatt acgctcgacc accatatcca tagttcctag atgactctct ttctgagaag
    16321 tgatttcctt agccagcaaa attaagcccg cacaggtccc aaacactggt aagccagata
    16381 gaatggcttc tcggatggga agtagcatgt tctggtcacg taagagcttg cccatggttg
    16441 tagactcacc accaggcaaa atcaaacccg acaagtcact ctgatcttgc tgaaaatcat
    16501 ctagatttct gagttctaca ctctcgacac ctaattgatc tagcactttt gcatgttctg
    16561 caaaggcccc ttgcaaggcc aatattccga ttttcatcta ttttcctcgt tcagccatga
    16621 gaatttggat ttcattttca ttaataccaa ccatggcttc tcctaaatct tcagagattt
    16681 gagctagaat ttgaggatta cggaagttag tcacagcctt aacaatggca ctcgctcgtt
    16741 taacaggatc tcctgacttg aaaatacctg aaccgacaaa gaccccctct gcccctaatt
    16801 gcatcattaa cgcagcatct gctggcgttg caacacctcc agcagcgaaa tttacaactg
    16861 gcaattttcc atgttcatga acatattgga ccaattctac agggacttgc aaatccttgg
    16921 cagcaacata aagctcgtcc tcacgtaagt tttgaatgcg gcgaatttcc tgattcatca
    16981 tacgcatatg acgaacagct tggactatat cccctgtccc tggttctcct ttggtacgaa
    17041 tcatggaagc accttcagcg atacgacgca aggcttcacc caaatcctta gcaccacaga
    17101 caaaaggaac ttggaattct ttcttgtcca catggaaacg gtcatcagct ggagatagaa
    17161 cttcactctc gtcgatataa tcaatttcaa tagcctctaa aatctgagct tcaacaaaat
    17221 gcccgattct gaccttagcc attactggaa tactaaccgc ttcttggatt tccttaatca
    17281 tctttgggtc gctcatgcgg gaaactcctc cagctgcacg aatatcagcc ggaattcgtt
    17341 ccaaggccat cacagctgcc gcaccagcag cttctgcgat acgagcctgt tcaggattct
    17401 gcacatccat aataacacca cccttgagca tctgtgccaa gtttttattt agttcataac
    17461 gattttcagt catttgtttt atcctcatca tttgtattgg tagctacctt ttcattttaa
    17521 gtcagaacag aatgaagcac aagataaaaa aactataatt gtatggggac agattagcta
    17581 aaaactatct gaccttaact taaggccaga tagctcattc atttttattt ttcagccgta
    17641 agggcagcca ttgtgatgta gttgtatggt ttgttgaagt gtggcaagaa gaagaggtct
    17701 gtcaatgcca atttatcaat tgtcacatgc tcttggatag caagtgagaa catgtggatt
    17761 cccatgctaa ttgcaatatc atgtgaaacc atttgggcac caagaatttc acggctatct
    17821 ttgtcaaaga caatcttaat tgctacttca tggttgtcat gtttcatgaa ttctggtttt
    17881 tgaagatcgt taaagcctgt ttcagttgcg ttgtaaccag cagctttcgc tttttcaaga
    17941 gtcaaaccag ttgaaaccat gtgaagaccg tagattgaga taccatttga accttgaaca
    18001 ccgattcctt ccaattcatg tccacaagca ttgtaggcac caacgatacc agtgcgaaca
    18061 gcatttgaag caagagcgat atagcttgta tctttacgag cattgtcata aacagtcgca
    18121 cagtcaccaa cagcgtaaac gcctgggata gatgtttctt gtttcttgtc tacaaggaag
    18181 gcaccgttgc ggaagagttc gatcttacca tctgcaaggg ctgtgtttgg acggaaacca
    18241 actgcaagga taaccatatc cacgtcaaag ctttctttgt cagtaatcaa gcgttcaact
    18301 ttaccgtcac cttcgattgc tttaacagtt tgacctagag ccaagcggat gttgtgatct
    18361 tccaagttct tcgccatcat ttgtgtgaag tctttgtcat agtaaccgtt caagacagta
    18421 tcaacgatat caacaaggac aacttctttt ccaagacgtt caaaggcttc agcaagttca
    18481 acaccgatgt aaccaccacc aacaacggcg atacggtcga ggtgttggct cttgtcagaa
    18541 agtttattga taacttcttc agcattttgg tacaatttca cgaattgtac gttttcaaga
    18601 gttgctttaa attcgcggtt tcctttaaca atttcaacac cttcgattgg tggcaagatt
    18661 ggtgtagaac ctgtagcgaa aatcaatttt tcgtatgatt ctttgtgctc ttttccttca
    18721 acttccgctg taactacttt gttatcatag tcgattgaaa gaacaggtga gttcatgtaa
    18781 actttagcac ctttagcttc caatttttct ttatcagaat agaacaagcc ttcagcaccg
    18841 tcaatttgtt caccaatcca aagagccatt ccacatccta ggaaagagat gttagagttt
    18901 tggtcaaata caacaatttc gttctcattt ccaaaattat ccaacatggt attgatacat
    18961 gctgtaccag cgtggttagc accgactaca acgattttac tcataaaaat ttcctgcctt
    19021 cattctaaat ttaccttact agtataccat ttaccgttag cgtttacaag gggggtacta
    19081 ttatttcagc attttttatc aaaaataatt ccccatttat cctgttttca agcctcatga
    19141 attttatgag catatttctt gactttttcc aaattttgtt tgtgaaaatt ctaactttat
    19201 ggtattataa taacatgaaa atgaaatgta agggcttcaa tttagatgat tatttgatat
    19261 tacaacttat tttctataag agaaaggagt tggtagcttg actcttcgtt cacattctga
    19321 acggctaatg gggactacta tcactatttc attagtggat gagcaagccg atatctttct
    19381 ccaaaaatcc tttgacttgc tcaaagaact tgaataccgc ttcaacgcca atagtcaaga
    19441 atctgagttg atggaaatca attatcaagc aggaatagcc cccgtcacgg ttcatccaga
    19501 cctgtttgag ctgatttcac ttgggttaga gcatagccta gcgctctcta gccacctcaa
    19561 tatcagcatt ggtcccttaa ttcaaacctg gcgtatcggt ttttcagatg ccaaggtcgc
    19621 ccagcctcaa gaaattgaat cggtgctgcc tctaatcaat cctcatggta tcgagttaga
    19681 ttcttctact tctactgtgt ttttaaaaca gaaaggaatg aagatcgatc taggttgttt
    19741 agccaaagga tacagtgcgg ataaggttgc ccaatttctt aggaaagagg gggtgacttc
    19801 tgccttgatc aatctgggag ggaatatcct gaccattgga aaaaatcagg caagagggga
    19861 taacccatgg caaatcggga ttcaagaccc agccaatcct aggggaaatc atttaatgac
    19921 catccctgtt atcaataaat ctgtcgtgac ttcaggcatt tatgaacgtc acctgaccgt
    19981 cgatggacaa gattaccatc acatttttga cagtcaaaca ggatatcctg ttgaaacgga
    20041 actagcgagt ctaacaatca tctctgataa atcagtcgat ggcgaaatct ggacgactcg
    20101 actctttgga gaaagacctg cttctatcct ctggcaagtc gaaagtttgg agggcatcga
    20161 agtcatcctc atcgataaag aaggccacct aagctgttct tcaggaattc ctactctata
    20221 gagacaactg tttcaatgga attttaaaat tgtattatgt aaaaagagaa aggaaatctc
    20281 atgttaaaac ttattgctat tgttggaaca aattcaaaac gttctacaaa ccgtcaattg
    20341 cttcaataca tgcaaaaaca cttttctgac aaagctgaaa ttgagcttgt tgaaatcaag
    20401 gccattcctg tcttcaacaa accagctgac aagcaagtac ctgctgaaat attggaaatt
    20461 gctgctaaaa tcgaagaggc agatggcgtt attatcggta ctcctgagta tgatcactct
    20521 attccagctg ttttgatgag cgctcttgct tggttgtctt atggtattta cccacttttg
    20581 aacaaaccaa tcatgattac aggtgcttct tacggtacgc ttggttcatc tcgtgcccaa
    20641 ttgcaacttc gtcaaatctt gaatgctcct gaaatcaagg caaatgttct tccagatgaa
    20701 ttcttgctct cacactctct tcaagcattt aacccaagtg gcgacttggt tgaccttgat
    20761 gttatcaaga aattggatgc catctttgat gacttccgta tctttgtaaa aatcacagaa
    20821 aaattacgta atgcacaaga attacttcgc aaagatgctg aagactttga ctgggaaaat
    20881 ttgtaagata ggagaccaaa aagaatgaaa tttgttggac ttgttggatc aaactacgat
    20941 caatcatata accgtaagct cttggaattt atccgtcgct acttcaaact caaatttgaa
    21001 ttagaagttc ttgaaattga cgaagttcca atgtttaacc aagatgaaaa atgggatgaa
    21061 agtttccaat tacgttattt atataacaaa attactcgtg cagatggtgt tatcattgct
    21121 actcctgagc ataaccacac tatctcagct tcactcaaat ctgtacttga atggctttca
    21181 tacgaagttc atccatttga aaacaagcct gttatgattg tgggtgcatc atactatgac
    21241 caaggaacat cacgtgctca agttcacctt cgtaaaatcc ttgatgctcc aggtgttaat
    21301 gcctacacgc ttccaggtaa cgaattcctt cttggtaaag ctaaggaagc ttttgataac
    21361 aacggaaata tcaccaacga aggcactgtt aaattccttg aaacttgctt agataacttt
    21421 gttaaatacg taggagtcgt ttcgaaattg aaaaaaccaa aaccaatcga atcagaagac
    21481 ttggattgtg gaaaaccaat cgctacaacc atcacagaag ttgaccctga cgatccagaa
    21541 tgggtagaaa aagttgcagc aatcactggt gctgtttctg gtgataccta tgtcaaattg
    21601 gaccacggta tcctaacagt taaccaaatt gatatgttct tgaaagctat gccatttgaa
    21661 ttgacatacg ctgacgacaa caaccaattc ctctactaca acaacgctca ccaagatcca
    21721 gacactatgt tcgctaaacg tgtaccacct caatcaggta gccgtatgtc gactgttcat
    21781 ggttctcttc caccagcacg tatgaagaac gtagagtggg ttatcggaac acttcgcaac
    21841 ggaaaccaag aatacgtccg tacgatcgtt ccaggttctc ctgcaggtgt tatcaacact
    21901 cacaactacc aagcaatgta ctatcctgat ggatcatacg ctggtatcaa tgaaatcgtc
    21961 tttaacttcc aaccatggct tgactggtac ctaaaagaga ctggtcaacg tttggtgggt
    22021 ggtagcggac catttgctcc tgctgccgga ggtcatggag acgccgatgc tacttctggc
    22081 gcttctgatt caggggatgc tggaggccac ggtggtgacg cagacgctac agccggtgca
    22141 agttactaat gatagttttt aggaaccatt atggttcctt ttttagcgaa aaaagactag
    22201 caaacacaaa ctgctagtct ctttgttatc gtttcatcta tctttgttaa aagaaagagt
    22261 acttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc tgtacttaag
    22321 tacggcaagg tgaagctgac gtggtttgaa tttgattttc gaagagtatt attatgaatt
    22381 tgggtcatca agactacggc catgtaatcc tttttcacgt tgtacttggc gtagtttttc
    22441 tggtgtaaca tcgtttcctt cttcgtccac aattttgatt ccttcaatgt ggtgacgaac
    22501 agcgcggcga taaccttcga tgtactcctc acgtagtttg gcttgttcca ctttttcttc
    22561 tgatgttaag ccttctgttt ttttcttttt agcaagctca ttgatacgag caattttttt
    22621 cggatccatt tcttctcctt tgtaataaga taaagtccgt ttatcaaatt ttatttagtg
    22681 ttaatttggt taaaacaagc aaacttagct gctttcttgg ttagttgtga caagattgcc
    22741 aaacgatttt gacggacagc ctgatcttca gccattacca tagtattttc aaagaaagca
    22801 tcaatgactg ggctaagcgc aaagagttgt ttcaattgct gacttgcagg tcctgataaa
    22861 acgagtgttt ctactgcttc tgccaaagct ttttcttggt cattctcaaa tagtgctgaa
    22921 tcaactgtag caaccccttc tgccttctca gccaggttaa aggcacgaga aagtgattca
    22981 acagatggtt taaaatcttc ttccttgctt acttctacga gagcacttgc tgcttccaac
    23041 atatctgcca caacaaagtt tgaacctgca agaactgctt ccttgatatc ttttggagta
    23101 gagcccatca tcttatcaac acgagccttg ataaagtcca taacctctgc tttattttca
    23161 taagtcaaac tgtcaaattt caatgcataa aggctatcaa tcagctcatc catagcaatg
    23221 tgccaaccaa aggcatccaa gatacgaacc acaccttgag ttgcacgacg aagggcataa
    23281 gggtcattag aacctgatgg aatcaatcct actgagaaga aactcaaaat cgtatccaat
    23341 ttgtctgcaa tggctagaac tgcgccgacc ttgctctctg gaagttctcc ttcagctgat
    23401 gtaggcatgt agtgttcacg aatagcagct gccaccgctg gagtttcacc agcaagaagg
    23461 gtgtattttt cacccataat tccttggagt tcgtcaaatt caccaaccat acctgtcaac
    23521 aagtcaaact tgtaaatggc tgctgcacga gcaaggtcaa ctgtttcatc cactgacaaa
    23581 ccagcttttt ctgccaaaag tacagtgatt tgacccgtac gaatcatgtg ttcacgaagg
    23641 gaaccaatct tctcatggaa ggtgacattg tttaattttt caacaagatc tgaaatcacc
    23701 aatttttggt cttcacgcca gaagaattct ccgtcttcca agcgggctac caagactttt
    23761 tcatttcctt tgatgacatt tttcaaacgc tctgcgtttc cgttacgaac agaaatgaag
    23821 tttggcaaga gttttccatc ttgatcacga acaacaaagt aacgctggtg ttccttcata
    23881 gaagtcacca agacttcttc tggaacttca aggtatttag catcaaaact tcccatgaag
    23941 gcagttgggt attcaaccaa attcaagact tcattcagca aatccgcatc aatttcgata
    24001 cgtacaccat gttttgcctc aatttccttg atttggtcaa caatcatttg ctcacgttca
    24061 catggatctg cgattacaaa ctgcttacga aggtcttctt catagctcaa tgctgactga
    24121 attttggttt ctttccccaa gaaacgatgg ccacggctca cacgacttcc cttgatatca
    24181 aggaaatcca agtcaaactc ttgctcatcc aagagaacag ttaaagtgtg aacagggcgg
    24241 atgtattcaa agctatttcc agcccagtgc atgctgacag ggaaagtcaa tgacttcaag
    24301 acatctacaa caccaggaac aatggcttca actgcttgac caacttcttc cttagtgaca
    24361 tagacatatt cttcaccctt gatttcacgg aattcgatat cttcaacagt caaacctttc
    24421 ccacggacaa atccttgagc tgctttggtg aagtttccat cactatccaa ggcaattttc
    24481 tttgctggtc ccttgaaatc ttctgtcaaa tcagactgtt tgtctgataa accagtcaca
    24541 cgaacagcca aacgacgtgg tgttgagaag gtttgaatgg cttcaaaaga caggcggttt
    24601 tccttgagga aggctgccat tttttcgcct agttgttttt cacttggtgt gacaacatag
    24661 gctggtaatt cttcaagacc gagttctact aataagtttt ttgtcatgtt ttttctccga
    24721 aaagtatctt tttattttcc agtttgcctt atgtgattgg cacgcaagca accaacttcg
    24781 ttgtttcatt gctaaaattg gagccaaaag tctccaattt tgcctagtat ccttagtttc
    24841 actaaggata ccttcatcac tgcggcaact ggctcagggc tcactctgtt cgcccatttt
    24901 cgtaatttgt cactctcttt attctgcgtc ttctgctagg agtttagctc ttgtttcttc
    24961 atccaaaagt gggtagccta ggcgtttgcg ttctgcgaca aaggttttgg ctacgacacg
    25021 ggccaagtta cggatacgag cgatatagcc tgcacgctct gttacagata cggcaccacg
    25081 cgcgtcaagc agattaaagg tatgtgaaca tttgagaaca tagtcatagg cagggtgtac
    25141 caagccttct tctaatgcac gaccagcttc tttttcaaac ttatcaaaat tttcaagcaa
    25201 catttcttgg tccgaaattt caaatgaata ttttgagtgc tcatactcag gctggataaa
    25261 gatttctccg tattttacac catcagccca ctcgatatca tagacagagt caacttcttg
    25321 aatgtaagaa gccaaacgct ccaaaccata ggtaacttcc gcagtcacag gaccagttgc
    25381 caatccaccg acttgttgga aataagtaaa ctgagtgatt tccatcccat caagccaaac
    25441 ttcccaacca agaccagctg aaccagtcga tggattttcc cagttgtcct caacgaaacg
    25501 aatatcgtgt tccaaaggat tgatacccaa tttttccaaa gactcaaggt aaagctcttg
    25561 gatatttgat ggagaaggtt tcataaccac ttggaattgg tggtgttggt aaaggcggtt
    25621 agggttttcc ccataacgac cgtcagcagg acgacgtgat ggctctacat aagccgcatt
    25681 ccatggctca ggtccgatag cacgaaggaa agtgtaagga ctcattgttc cagcaccttt
    25741 ttcgttgtca taagcctgca taagcataca accttggtca ttccaaaatt gttgcaaagt
    25801 aaggatgatt tcctggaaag tcaatttttt agacattatt tactcctttt aattaaaaaa
    25861 atttgttttc tttatttcat tttcttttaa aactattatt gagaaattat ttctcttttt
    25921 ttgcatgttt atcaatttat caatactaca aaagacttca tttgttgtta caagtattag
    25981 ttttttatat ggttttctat tagtttcaat tgaatagtta tccgataatt catataattt
    26041 cgtaatatac ctatctaaca ctgaactccc aatatta
//
LOCUS       DAVMJI010000029        25785 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.029, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000029 DAVMJI010000000
VERSION     DAVMJI010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25785
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.029"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            308..484
                     /locus_tag="VYR58_001496"
                     /pseudo
     CDS             308..484
                     /locus_tag="VYR58_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            900..1289
                     /locus_tag="VYR58_001497"
     CDS             900..1289
                     /locus_tag="VYR58_001497"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV3622629.1"
                     /translation="MKAQAIVTSQGRIVSLDITVNYCHDMKLFKMSRRNIGQAGKILA
                     DSGYQGLMKIYPQAQIPRKSSKLKPLTVEDKTYNHALSKDRSKVENILAKVKTFKMFS
                     TTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            complement(1359..1721)
                     /locus_tag="VYR58_001498"
     CDS             complement(1359..1721)
                     /locus_tag="VYR58_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622630.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSLEQYPDYDGFDYEEW"
     gene            complement(2099..3979)
                     /locus_tag="VYR58_001499"
     CDS             complement(2099..3979)
                     /locus_tag="VYR58_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV3622631.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGSETAQFSILSSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(3973..4842)
                     /locus_tag="VYR58_001500"
     CDS             complement(3973..4842)
                     /locus_tag="VYR58_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV3622632.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(4926..7571)
                     /locus_tag="VYR58_001501"
     CDS             complement(4926..7571)
                     /locus_tag="VYR58_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV3622633.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKDHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLSRQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(7662..8942)
                     /locus_tag="VYR58_001502"
     CDS             complement(7662..8942)
                     /locus_tag="VYR58_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV3622634.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSESIIADTKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            9113..11197
                     /locus_tag="VYR58_001503"
     CDS             9113..11197
                     /locus_tag="VYR58_001503"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV3622635.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKSSAQADWENLLHRFDIIEIGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQERGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(11237..12916)
                     /locus_tag="VYR58_001504"
     CDS             complement(11237..12916)
                     /locus_tag="VYR58_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV3622636.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGE
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GSALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFSRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGEALHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            13671..14900
                     /gene="arcA"
                     /locus_tag="VYR58_001505"
     CDS             13671..14900
                     /gene="arcA"
                     /locus_tag="VYR58_001505"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV3622637.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            14958..15974
                     /gene="argF"
                     /locus_tag="VYR58_001506"
     CDS             14958..15974
                     /gene="argF"
                     /locus_tag="VYR58_001506"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV3622638.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            16139..17086
                     /gene="arcC"
                     /locus_tag="VYR58_001507"
     CDS             16139..17086
                     /gene="arcC"
                     /locus_tag="VYR58_001507"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV3622639.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            17297..18808
                     /locus_tag="VYR58_001508"
     CDS             17297..18808
                     /locus_tag="VYR58_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV3622640.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            18830..20161
                     /locus_tag="VYR58_001509"
     CDS             18830..20161
                     /locus_tag="VYR58_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV3622641.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICQDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLYGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAIYRLAT"
     gene            complement(20567..20857)
                     /locus_tag="VYR58_001510"
                     /pseudo
     CDS             complement(20567..20857)
                     /locus_tag="VYR58_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20845..21096)
                     /locus_tag="VYR58_001511"
     CDS             complement(20845..21096)
                     /locus_tag="VYR58_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV3622642.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(21494..22378)
                     /locus_tag="VYR58_001512"
     CDS             complement(21494..22378)
                     /locus_tag="VYR58_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV3622643.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(22523..23674)
                     /locus_tag="VYR58_001513"
     CDS             complement(22523..23674)
                     /locus_tag="VYR58_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV3622644.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFRDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGRPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(23820..25586)
                     /locus_tag="VYR58_001514"
     CDS             complement(23820..25586)
                     /locus_tag="VYR58_001514"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV3622645.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
BASE COUNT         7405 a         5727 c         5094 g         7559 t
ORIGIN      
        1 aatagatata aaattataac tttgctagcc gttgttataa aaagttttat tcaatcatta
       61 tctagtagaa tagagtagta cattttataa attgtcatct ctccataaac acagtatatc
      121 atttttaaat tttaagtcaa gaaaaattaa cccactttaa tttctttttt aacccgtgtt
      181 aaaaaagaaa ttaaagtggg ttaaaaaaga aattaactga gtaaaaactc tcgaaattca
      241 attcgctata ttatcactca acttgaacaa ataccagaac cacaaaaaac agatgtaaag
      301 gaaaaatatg gacttaaaat ttgaaggggt tgatttagaa tacaaaaaag ctaaaaacaa
      361 tcttccagag tctttctggg aaacctactc agcatttgca aatacaaatg gcgggaaaat
      421 aattctcggg atagatgaaa aaaacattga cacctaccaa agagtcaata gactccctgc
      481 gaaacaaaat tatgaagcaa gtaaacaact aactgatgca cgatttaagc tccttgttgg
      541 tgttcagcgt accacttttg aagagatgtt agctgtatta aaaacagctt atcaacttaa
      601 acacgcaaaa ggtggacgaa aacctaaatt aagcctagaa gaccttctta tggccactct
      661 tcaatatgtg cgagaatatc gaacttatga agaaattgcg gctgatcttg gtattcacga
      721 aagcaactta atccgtcgga gccaatgggt tgaagtaact cttgttcaaa gtggtgttac
      781 gatttcaaga actcctctca gctctgagga cacggtaatg attgatgcga cggaagtaca
      841 aatcaatcgc cctaaaaaaa gaattagcga atgattctgg taaaaagaaa tgccacgcta
      901 tgaaggctca agcgattgtc acaagtcaag ggagaattgt ttctttggat atcactgtga
      961 actattgtca tgatatgaag ttgttcaaaa tgagtcgcag aaatatcgga caagctggta
     1021 aaatcttggc tgacagtggt tatcaagggc tcatgaagat atatcctcaa gcacaaattc
     1081 cacgtaaatc cagcaaactc aagccactaa cagttgaaga taaaacctat aaccatgcac
     1141 tatctaagga tagaagcaag gttgagaaca tccttgccaa agtaaaaacg tttaaaatgt
     1201 tttcaacaac ctatcgaaat catcgtaaac gctttggatt acgaatgaat ttgagtgctg
     1261 gtattatcaa tcatgaacta ggattctagt tttgcaggaa gtctattgaa atactaagcc
     1321 tacacagact gattccaatt gttttttaga tttcaatttt accattcttc atagtcaaaa
     1381 ccatcataat ctggatattg ttctagcgac gttccaaccg aacgtacgag ataagcttct
     1441 tcgtcctctg tctcgatttc tctcagcact tggcattcaa aacgccattc atcaccgaag
     1501 tcgaaaataa acttaaattt ttgtttgaca cttaggctat ccagatagac attttctgtg
     1561 taacgttctt caacatcgtc actaacaaag ctaagaaagt aagaatctgc atgactccac
     1621 tcaacattat ccatgaaaaa tgcgtgagca tgatcatttg caaaatcaaa actccataaa
     1681 atcacatctg ctagttccgc taacgttttt gtttttggaa tctatatatg tcggtagcaa
     1741 cctttttaaa atttgacgga aatgatccaa gcttctacag atgctggctt ttcagcttct
     1801 atttcttgtt ttactaattt taagtgtagc ataatacctc caattgctca tcgatagaat
     1861 tgctcttagg aaacattcac tttctgctat tttatcataa gtttgtctaa ctgtagcatt
     1921 tgaaaccaga taattcttct gtttcacgcg aaacaccctg cgccaagcaa ggtgttcttg
     1981 tttttatact caatgaaaat caaagagcaa actaggaagc tagctgcagg ctgctcaaaa
     2041 cactgttttg aggttgtaga tggaagctga cgtggtttga agagattttc gaagagtatt
     2101 aagtcgtata aatcgtcgaa gctgtcgcaa tggtatgcca ctggttagct gtagttgctg
     2161 cgaaatcctt gtctgcgtag aagtcagtaa atggtaggat ttcaacttcc agctcgtcga
     2221 tgcggtcaag ctggccagcc agataaacct cgatacggct ttctgctcgt ttgatgcgtt
     2281 gcaagagtcc gcccatacgg atgtcaactg tatccaaacc aaagaccttg ttttctttca
     2341 gccattggtg actaaagagg gcatggaagt cttcaatttg gcttctaagt tctggtaatt
     2401 cttgtctggc gatttgttgt aaactttctt tatcatccgc ttggtaggcc tgacgaatgc
     2461 gtcgtcccac atctactttg ctacttaaaa tagcattcaa ctgggcctga gtttcaaaga
     2521 gataagcata gtttccagct ttttctttaa tgttagcaag cgtctcagca gcctgagcga
     2581 agtgcggttt gtcctgttca ggtgtcatgt gtcggtcaag tatcggacaa agaacatcct
     2641 gataaaaaac atagcggttg ggattgatac cgctgagatt gcctggtagg tctggtaaga
     2701 ggttggcaag gtcaatctgc ataaaatcct caaccgttag accagtattg gtcttgaagt
     2761 gcgcagacaa actatctagg tcattgcgat agctgagttc tgcccagatt tgcaagcttg
     2821 ataggataga gaactgggca gtttcactac cattgtctcc ccaacccgtt acgatgactt
     2881 ctttaatctg attggcacgg caggctttat tagcctcgat agccactaga cggctaaaat
     2941 ggttgtgagg tgtaaagcca atccacttcc aagctccccc tgcaaatgca aggtcatggc
     3001 taatcttgtg atgattgcgg aaattacggt tgtatttttc ctcgctatcc tgataataat
     3061 cccagtaaac cagagtcaca cggtctttga gacggtctag gtagacacga gtttcctctg
     3121 gaatttccac atcacggtcg tactggccat ccgctgacat gagtttgaag aacatatcac
     3181 tccacatctg gcagtggaaa ccatatttgt cagcaatatc cagcacgcgc tccaagtgtt
     3241 ggcacatgag gagactacga tccacaacac cgttcaaaat caggtagcgt cccaaaccaa
     3301 ccaagtgggc ttcgtccatc ccgatattga ccttgcgagt cttcagttta gacaacgtgg
     3361 caaacatgcc atcaatcagg tcataaacct tttcttcgcc aatgagaaga atgtcctcta
     3421 catcacggag ctcctgcact tccttgacac cccatttgac aaaggccgac aagtgggcca
     3481 aggtctggat gcatggtaca aaggtcatgt caaactgttg agcataggct tcgatttcct
     3541 gcaactcctc tgctgaataa gctccacgga aatagccaaa gtaaggctgc ccttcaatct
     3601 ggtaagtgtc ttccatgtaa agctcaaagg ttgagtagcc catgagagcc aagacctcaa
     3661 tcatctgctt ggcagaagcc acattcagca ccgcatttcg agaacagtca accatgtaag
     3721 ccaaatcttc gtaagctgct tgttcctcaa tctctacttt atcagcttct gctagaactg
     3781 ttaccaacaa ggataaggca cgataaagtt ggtgaggttt gcggtaggtc aattgatagt
     3841 gaccttcctc accctcgata gagatagagg cttggtcaga ctgagtgaca gccacttcca
     3901 catctggtag agaaatatga ccttttaaaa cctcaatagc ttgcgtttgt ttgggactaa
     3961 gtcctgtaaa tcttaccatt gcttttcctc ctgtagccag ttgacaaggg caccgtagag
     4021 attggcatct gcgtgatagg tgcaggtctg gataactggt gcgaccgtgt attcttcgta
     4081 ggtatcgaca aagttatcaa cagccttctt gacatcttgg ataaaatctg gattttgact
     4141 gatagagcca cccagactga tgacatctgg atcgatgaga tactggatat tgagcaagcc
     4201 ttgcgccaga ttgcggttca tgcgctcaat ggcttcttga caaagagcat taccagctgc
     4261 ggcctcttgg taaatcttgc gaccgtccca atcagtatga ccagattttt caatcacgta
     4321 tcgtaccata ttcccagttg atgctagttg cgaccagtta ttaagttttt cagcaggggc
     4381 aagggttgtc atgtagccaa attctccacc caagccgtgg cgacctcgat gaagtctacc
     4441 attgataatc atggctccgc caatccctgt cccaatcacg acacaggctg cattttcaag
     4501 ctctggatga gctagtagtt cactgagtcc aacgcagttg gcatcatttt ctaaatggac
     4561 aggtagctga taagagctaa gcgcctcata ccaagaaaag ccatggatgt agggcaccgc
     4621 actgaagcca tcaatcacac ctgtctcttg attgaccgca cctggaacgc tcatagcaat
     4681 cccactgtaa tcctgttctg acaagcgttg atctagccac gctagtaaat cctccaagtt
     4741 ttcaggcgtt gaaatacttg tcttatccag tattttccca tcaggagtca gactggcaaa
     4801 cttaatccca gtccctccga tatcaatcgt tgcaatggtc attgttttta ccataaaaag
     4861 gggcgaatca gcagttagtt cttacctttt cgcccctcct ttcttttgat gtttactttt
     4921 tgaaattaaa tttcttcttt tttgatgaat tctgtacgaa tctcttgtgg agccaatagt
     4981 cctgaatgaa ctggatatgg tcgctcaagt aagtcaagaa tggtttgttg atgttctgat
     5041 atgcgcacat tttcttgact catattatag taacggagga catagccttc ttcattttcc
     5101 gccactttaa aggctgttgg acaaacttgc ggtatgctga gaacagaatg gctcaagagg
     5161 ctaccagtcg caaccacgct tccttcctgt ctagaaagct gaaggctggt aaacggtgtc
     5221 tgcaaggctt tggcacgacg ataggctgag aagcgttctt gggcttggtg gcattcaatc
     5281 gcaaattcga cttcaaactc acgcaagcat tgtgcttctg gcgttgggaa gtagccccag
     5341 tcacctagct cacctgatgc acgcaaaatg gtcacggcaa tggtgttatc cccaaggatt
     5401 tcgtattcat tcaatccctt gttggataca gtcacccctt tttcatcgtc atacagactg
     5461 acaaaagctt gttggtgttg aggattttca ggattttccc atgaagcagc tggtttgttt
     5521 ggtcgtgtca ccacctcata gatactttca gaatcattgc ttggacgcgt gttatgagtc
     5581 ttgaccaaga gacggatacg gtgatccttg gcagtgttag taaagcgagt cttgaagcgg
     5641 atttgtggat tgtcaacgaa gacagtcaac tcagtttcca gaggaatgtt tgtcaattct
     5701 tctgaccgtc cagcctcacg cttcataaac tcgatgatac cttgttgctc ttcttctagc
     5761 ttttcatccg cactgacagg cacggtcaat tcatgtttga gcaagatttt agcatagcga
     5821 tctgtgtttt ccaagacctc gtggtcctta agctctgcaa agattggctc tgttcctttt
     5881 ggttggaaat agatatactc gtttccgatg tcaccccggt cttcaaagcg gataaagtct
     5941 tcataggctt cgtgagttgt cttatcatag actgtgatgt tgtcatccac actcaccgtt
     6001 acgaatggtg tatcaatcac tccgttttgg taaataccct cacggtgttc ttgttctcct
     6061 tccagcaatt ggaaggttgt ccaagaaagc ggtgctaggt gaactggaat ggtcacgcgc
     6121 acttgtcgag caatacgagc ttggcggaac ttgtcttttg gtaaatcgta ttcaaaatta
     6181 gctccgaggt cttcgattgt agcctctaca ggacgaccat ccaagtcctc cacacggtaa
     6241 cttggcaaga taagagcagc catctttttg tagccttctg ttgggtgcaa ttccttgaaa
     6301 tcacaagtcg ccacatcaat cactgtgctg acagtatcga ccttatcatg caagcctgtg
     6361 ttaatgacag taaagagata gtcactttga gccttatccg tagcaatttt acccttccac
     6421 tcgttgagca aattactttt aacaaagttt cctacttggt tgaccttggc aaaacgcgtt
     6481 tccatctcgc ggtgaacttc gtccacgcta cagccacaga tactatcatg tggcgcattc
     6541 tgcaaaagtg ttttccaagc ataggtcaac tggtccttgt ggttgtgtcc accagtgata
     6601 atagtcaagg gttctaccac ttgctctagg aggttgctat tttcttggaa ggcttgtttt
     6661 aggtaaatgc gggatgaaga agtgttggca agtgtgtacc agccatctgt ttcctgactg
     6721 gtcaactcac ctgtaacagt tgataagtgt tcaggaagcg caccttctac agcttgaaca
     6781 tattcatcaa aagaactatg aacaaagatt acatccggga agagttcatt tgccacacga
     6841 atggcttcgc tcagattttt ctggacaggc tggtggtcac agccgttcat catcaaccat
     6901 tggttggtcg aagcgtaggc acgcacatct gacaattttt gtttccagaa ggtcaaggcc
     6961 tcatctttgt caactgggat ttcattccca ttactgtacc agttggcaaa gagaatacct
     7021 aaaacacgac taccgtccac accctgccag tacatttctg aaaactggga tgtaaactgc
     7081 tcatcttcaa ggacttggtt gtcaaatcca atcggcttca caccacgacc aaaggccgcc
     7141 acgtgaatgc ctgatttttg aagaatttga ggcgcttgtc ccatatttcc aaaggtatct
     7201 ggaaagtagc caatctgggt tgatttaccc catttggcag cttcttgttg accaatcaag
     7261 gtattgcgga cattggcttc actggagatc aagtagtcat cctgcaagat gtaaaaggga
     7321 ccaattttaa gtttgccctc gtcaatgtag cgttggacct tgtcacgatt ttcagggcga
     7381 atttgtaagt agtcgtcaag gacaatagtt tgtccatcca agtggaaact cttgaactca
     7441 gggtcatttt caaagagatc aaagagattg tcaaacaatt ccaccaactg catacgatgg
     7501 ctttcaaaag gcaagtacca ctcacggtcc cagtgactat gtgagataat atgtacaaca
     7561 acattttcca tgaagtaaaa cctcattcta aatttaaatt ttaacgtttt aaatgtaaac
     7621 ttgtgattct gataagaatc ggttgagcta aagcgagccc cttagcggat atccaagtaa
     7681 tccaagacca actcacagaa catcatgtta gcccaggaga accattcacg agagtagagg
     7741 gtcggatcat ctacgtggaa gctttcgtgc atgacacctg taccaccatc gcaggcaacc
     7801 agctgatcca gcaagaattt tttctctgcc ttatctcttg ttgtcaatcc ttggatagaa
     7861 agggcgattg gccagatata gcgatagaag gtatgagaac ttccgagacc gctagcgtat
     7921 tctccttggt agaagtatgg attttcagag ctcaaaatgg tacggcgagt agcttgatac
     7981 acttcatcat cgaccgaaca gtagcccaga tagggcgcag ctagtagact tggtacattt
     8041 ggatcatcca tgatgctggc atttcctagg ccatccactt caaaagcgta aatcttttcg
     8101 cccttgctgt tggtggtgta agcgtagttt tcgattcctt cttggatttc atcctgaaga
     8161 cgcttggtat cagcaataat gctctcgcta tcagctaggt ttaatgctgc gaagatttct
     8221 tgcacataac ccaagactac tacagcaaac atatttgacg gaatcaagta actatactgg
     8281 caacagtcat cactcggacg aaaggctgac caagtcatac ctgtcactgc aaagtcaggt
     8341 ccaaagccat catttaccaa ggtgtcttcc ttacggtccg tatctcggac aaaacgataa
     8401 ggagagttct tgtggtcttg ttcaactgtc catagatgga gaatttcctt agtcgctgcg
     8461 acaaaagtct catcaaactg accagtctcg ccagtctctt tccagaggag ataagccaac
     8521 tgcaaaggat agcaaagtga atccacctca tacttgcgct cccagatcca gccgttaagg
     8581 tctgtgtggt cagtctcgtg gtgccctttc cagttcttct caatgttgaa ggagttagca
     8641 tagggatcct tgagtaccaa ggtcatctga cgtttgacca aacctgcaat ggtctgacgc
     8701 aggagggcat ctcttttagc tacatgaagg tagggtctga gttgggctgt cgaatctcga
     8761 agccacatgg caggaatatc cccagtcaag acaaaagttg aaccatcttc taagatttca
     8821 accgtattgt ccaaggtatc ggtgtagcaa cgctcgaaaa catccaccca ctctggatgg
     8881 tccttagccc gctctgctac ttcatctagc cattctctaa caatttcttt cgaataaatc
     8941 atcgtgcaat tccctctttc aaacaagttt catgttcagt atatagcttt tgagacagaa
     9001 aatacataca caaatgatag tcatttttct acaaaatagt tatttttgaa actccttttc
     9061 taaaggccct ctttttctga tataatgtag aaaaacagct aaaggaaaga ctatgaaacc
     9121 actacttgaa accatcgata cccgctttgg aactaccaac aagcatgcct tttctcgggg
     9181 aaataccctg ccatacacag gcgtgccttt tgggatgaat tactttgtgc cccagaccag
     9241 tgaccaggat ggatcttggt tttttgatcc gcatctgcct atctttcagg ggattcgatt
     9301 aactcaccag cccagtcctt ggattgggga ctactcttgg ctccttctga cacctgtcac
     9361 aggtcagctt gggggagaca gtctctttca ccgccaatct tcctatgata gggataaggc
     9421 ctctttccaa cctcattatc taaagatttt ctccctgcgc tatcagattg aaacccagct
     9481 cacaccgact tgctacggtg cttctattcg tttgaagcaa aagcaaggca aagccctctc
     9541 cctctatctt cacgcagcag atgaactgac agtagagcaa gtagataagc gaactcttgc
     9601 cctgcgacaa gaaggtaaaa ctgaaaccaa caaaaattcg ctaacgatgt tcactgccct
     9661 gcaaatgaac acggatattc ttgctatcag ccaagaagct ggggactggc gaattgactt
     9721 agcaagtagt caaaccgaga tgcaactagc cacttctttc atctctcctt ctcaagcact
     9781 gcttaatcta cctcaagaag attttgatag ctgtaaatca agtgcccaag cggattggga
     9841 aaatctcctc catcgttttg acattataga gataggagag gctgaccgaa ccttctttga
     9901 ccactgcctc tacagactct tcctcttccc acagactttt tatgaggttg atgagtcagg
     9961 gcaagccatc cacatggatc tggctactgg tactgtcaag cctggtgtcc tctttagcaa
    10021 caatggtttc tgggatacct tccgcaccac cttccccctc tttgccctta tcataccgga
    10081 gcactatcaa cgctttttag aaggtttcct caatagctac cgcgatactg gtttccttcc
    10141 aaaatggctg gctccagatg aacggggtat gatgccaggt acacttttag acggtattat
    10201 cgcagatagc gcctgcaagg acatggcccc tgacctagaa ggagaactct tccaagccat
    10261 gctcgaaaca gccagcaaag ccgaccctct cggcatcaat ggccgccacg gactagccca
    10321 ataccaagaa cgaggttacc tctctaccga ccaccacgaa agtgttagcc atactctaga
    10381 ctatgcctat agtgactttt gtatcgccag ctgtgccaaa aaactagaga acatagaaat
    10441 cgctgaaacc tacaaggctg cttcacaaaa ttaccgccag ctatttgacg ctgagacagg
    10501 ttacatgcga gcacgagaca atcaaggaaa ctttcaccct gacttctctc cttatagttg
    10561 ggggcgagac tacgctgaat gctctgccat tcaagctact ttaggcgttc tccacgacat
    10621 ccctggctta atccaactta tgggtggaaa agaaaccttt agcaactatc ttttgaaagc
    10681 ctgtcaagat gctcccctct ttgaaacaac aggctatggt tacgaaattc acgaaatgag
    10741 cgagatggct actgctcctt ttggacaaat agccatttcc aaccagccta gtttccacat
    10801 tccttatctc ttccgctaca gcgattaccc tgactacact gcccttctca tcaagacgct
    10861 ccgtcagaaa gcttttcacc caagttggga agcctatcct ggagatgaag acaatggtag
    10921 tctctctgct tggtacatct ggtcagctct cggattttat ccaacctgtc caggaaaacc
    10981 aagctatgac ctcggaatcc ctctctttga ccatctacga gtctacctag ctaaagaaga
    11041 taaatggctg gatatccata ctaaacaaaa ccacaaccat tttaactttg tcaaagaatg
    11101 ccgactgaac aaaacactcg tatcaactat tcaacaccaa gacctcttaa aagctgaaca
    11161 actaactttc accctcagct ggctaccaag tcactaataa ccaaaagaac ctttgcatcg
    11221 cgcaaaggtt cttcttttat gaaacttgga cttgaagttg atccacaagc tgaccatcca
    11281 ccgttaggtt cagatagaaa tccaaggttt tatctcctgc gaaatacagg gttggtagat
    11341 gcaaatcttt tttgctttcc cctgcttgga attgaaggac ataaatctcg tcctgatagg
    11401 cgacaccatg gacacctgtc cccggttgaa tcgaaatctt agcctctaaa gaggagctac
    11461 tttcactacg ttcaatccta aaatgaagag cctctccctt tgccacagct aggctttttt
    11521 ctgcaaatgc tagttcctga acaacttctt tttttgataa tccaggagtt ttataaaggg
    11581 aaatcttggt caatacagga atagattgtg cctcggtaat catcacgcgc accttttgtg
    11641 cctctactag cggacctcgc aagaggcgct tatgaccaac tgtgaagccc ctgctaaatt
    11701 cctgccagac accatccacc tctacttgca catgaaaagc agcgattcgt tgccctagct
    11761 tcaaatcttc tcttaactca attacatcaa aagttttagg agaacctaag tcgagttcta
    11821 actggatggg caagtctgca tcgcttgccc aagagctggt ctcaaggccg tctgtcaaat
    11881 ggcgacaagc aaagtctgcg gaaagagctg aaccagatac ctcagctccc agagccaaat
    11941 cttctttata gagctcattg cgataggtcg caaattcata aagtcgttca atatcctttg
    12001 catcaaagag cccagcttga ttcggcggaa tattaagcaa gagtggagtt cctcgcccta
    12061 ctgagtgaaa gtagatttcg accaactcct cgagagactt aggatcctga tcctcatggt
    12121 agaaccagcc tggacggatg gaaacatctg cctctccgat tgaaaaaatc gtgcccgagg
    12181 gatccccgtg ctgaagatag tccagctctg cttctgttcc tagtttatca ggattcacct
    12241 tttgccacag tggatcacct gcataccctc gttcattgcc aatccagcgg atactggtgc
    12301 cttctgttga aaaaatcaag caatcgccct gcaggtcacg aatggtttca aaccattttt
    12361 caaattcata attaaccttt tgcgcgccct ctcctctggc accatccatc caaacctcag
    12421 caaatttccc tccatttcca taggcaggat ttgataagat ttccttcagc tgagccagat
    12481 aataggcatt gtagtccgct tctcggtcca catgatagag gggactatgg gcatcccacg
    12541 gtgacaggta gacccccata tccatatcaa attctgtggc agcttgggat acttcaagga
    12601 gcaagtcgcc ctctcctctc ctccaaggac tgaccttaac cgaataatct gtgtgagctg
    12661 tcggataaag gacaaagcca tcgtggtgct tgaccaccaa aatcaacttt ttgaagcccg
    12721 tttccttgag cacacgaacc cactcacgcg catccaactg actcgggtta aagcgctcag
    12781 gatcctcctg tccagtcccc cattcttggt cataaaaggt attaggaccg aagtggataa
    12841 aagctgctag ttcatctccc agataagcta gctgagtctg acttggtaac ggtccatgcg
    12901 gtttgatttt cttcatcgtt atatatctcc ttctttagca acttctcttg ttcacaaggt
    12961 tatccacagg ttgtggataa taaaccatga tctaacagcc agctctttcc aactccaact
    13021 ggtaggctca ggatttttct cctcaatatt ccctcttcaa acagctctgt catatgattc
    13081 tgctaacacc tctcagaatg ctactctcca taattattct caggcttctt tcaggtcatt
    13141 gtgtgaagac cattcactct ccagactttt ccacagattg tgaataagtg attattctaa
    13201 gctatcacct cgtcgactat aacaaaaaat aaaaagaggg tcaataagat aattatctct
    13261 tcctaaatac tcagaaaaga ttctataatt tgtacaattg aacaagaaat gcttctccaa
    13321 aatctatctt caaaagaatg ttgcatcttt ttatcctttc acacaaacat ttctctttat
    13381 acagatccaa gtgataacca gatgataatt ggacactttt tggtcatttg tatatttttt
    13441 gaaaaatttt ttaaaaaaat tttatatcct ttttatagaa gtttatgcat ttgtatctat
    13501 gtattctatc ctatgttatg tataataaca taaaattgtg ctaaacatca taatttatat
    13561 tattttccga gaaattatag ccattgacat tacctaggaa ttgcgttata acatacatgt
    13621 aagcggtacc caaaatggtg ccaagtcaaa atttttaagg aggaaaatac atgtcttctc
    13681 atccaattca ggtcttctca gaaattggga aactgaaaaa agttatgttg caccgtccag
    13741 gcaaggagtt agaaaacttg ttgccggact atcttgaaag gcttcttttt gatgatattc
    13801 ctttcttgga agatgctcaa aaagaacatg atgcatttgc ccaagctctt cgcgatgaag
    13861 gaattgaggt tctctaccta gaacaactcg ctgctgaatc attgacctct ccagaaatcc
    13921 gcgatcaatt tatcgaggaa tacttagacg aagccaacat ccgtgatcgt caaactaagg
    13981 ttgctattcg tgaattgctt cacggcatca aggacaacca agaattggtt gaaaaaacaa
    14041 tggctgggat tcaaaaagtt gaattgccag aaattcctga cgaagctaaa gatctaactg
    14101 acttagttga atcagattat ccatttgcaa ttgacccgat gccaaacctc tatttcactc
    14161 gcgacccatt tgcaacaatt ggaaacgccg tatcgcttaa ccacatgttt gcagacactc
    14221 gtaaccgtga aacactctac ggtaagtata tcttcaaata ccacccaatc tatggcggaa
    14281 aagtggattt ggtctacaac cgtgaagaag atacgcgtat cgaaggtgga gacgagctag
    14341 ttctttctaa agacgtcctt gcagtaggta tctctcaacg tacagacgca gcttctatcg
    14401 aaaaactttt ggtcaacatc ttcaagaaaa atgttggctt caagaaagtt ttggcctttg
    14461 aatttgctaa caaccgtaaa ttcatgcact tggatactgt cttcactatg gtagactatg
    14521 acaagttcac tattcaccca gaaatcgaag gcgaccttca cgtttactca gttacttacg
    14581 aaaacgaaaa acttaaaatc gttgaagaga aaggtgactt agctgaactt cttgctcaaa
    14641 accttggtgt agaaaaagtt catttgattc gttgcggtgg tggcaatatc gtagcagctg
    14701 cgcgtgaaca atggaacgac ggttctaaca ctttgaccat cgcacctggt gtggtagttg
    14761 tttatgaccg caataccgtg accaataaga ttttggaaga atacgggctt cgcttgatta
    14821 agattcgcgg aagtgaattg gttcggggcc gtggtggacc tcgttgtatg tctatgccat
    14881 ttgaacgtga agaagtgtaa tcgctgttcg gtattcgtca atagaaaatg taaaaaatag
    14941 aaagaggaaa taataaaatg acaaattcag tattccaagg acgcagcttc ttagcagaaa
    15001 aagactttac ccgtgcagag ttagaatacc ttattggtct ttcagctcac ttgaaagatt
    15061 tgaaaaaacg caatattcaa caccactacc ttgctggcaa gaatatcgct ctcctatttg
    15121 aaaaaacatc tactcgtact cgtgcagcct ttacaactgc ggctatcgac cttggtgctc
    15181 acccagaata cctcggagca aatgatattc agttgggtaa aaaagaatct actgaagata
    15241 ctgctaaagt attgggacgt atgtttgacg ggattgaatt ccgcggattc agccaacgta
    15301 tggttgaaga attggcagaa ttctcaggcg ttccagtatg gaacggtcta actgacgaat
    15361 ggcacccaac tcaaatgctc gctgactact tgactgttca agaaaacttc ggtcgcttgg
    15421 aaggcttgac attggtatac tgtggtgatg gacgtaacaa cgttgccaac agcttgctcg
    15481 taacaggtgc tatccttggt gtcaatgttc acatcttctc accaaaagaa ctcttcccag
    15541 aaaaagaaat cgttgaattg gcagaaggat ttgctaaaga aagtggcgca catgttctca
    15601 tcactgaaga tgctgatgaa gcagttaaag atgcagacgt tctttacaca gacgtttggg
    15661 tatcaatggg tgaagaagac aaattcgcag aacgtgtagc tcttcttaaa ccttaccaag
    15721 tcaatatgga cttagttaaa aaagcaggca atgaaaactt gatcttccta cactgcttgc
    15781 cagcattcca cgatactcac actgtttatg gtaaagacgt tgctgaaaaa tttggtgtag
    15841 aagaaatgga agtaacagac gaagtcttcc gcagcaagta cgctcgccac ttcgatcaag
    15901 cagaaaaccg tatgcacact atcaaagctg ttatggctgc tacacttggt aacctttata
    15961 ttcctaaagt ataattttag ataataaacc gtctaccaac agctatgagg gctgcgacta
    16021 atagctttag tccggtcctc ttttatgtaa tggtaatcta ttatttctta taaaatatgt
    16081 gaaaaatcat taaattgaaa tctaaacgca ttctattgag tgtgataaag gagaatttat
    16141 ggcaaatcgt aaaattgtag tagctttggg aggaaatgcg attctttctt ctgacccatc
    16201 agcaaaggct caacaagaag ctttagttga aacagctaag catcttgtaa aattgattaa
    16261 aaatggagat gatctgatta tcactcacgg taatggacct caagttggga atctcttgct
    16321 ccaacatttg gcatcagact ctgaaaagaa ccctgccttc ccactcgact cacttgtcgc
    16381 tatgacagaa ggtagcatcg gtttctggtt gaaaaatgct ttgcaaaatg ctctcttgga
    16441 tgaaggcatc gaaaaaaatg ttgcctctgt tgtaacgcaa gttgtcgtag ataaaaatga
    16501 tccagctttt gttaacttga gtaaaccaat cggtcctttc tattcagaag aagaagcaaa
    16561 agcagaagcc gaaaagagcg gagcgacttt caaggaagat gctggccgtg gctggcgtaa
    16621 ggtcgttgcc tcaccaaaac ctgttgacat caaagaaatt gaaaccatcc gtactctttt
    16681 aaataatggt caagtcgtcg tagctgcagg tggtggcggt attcccgttg tcaaagaaaa
    16741 caatggacat ttgactggtg tcgaagcggt tattgataaa gacttcgctt cccaacgttt
    16801 ggcagaattg gttgatgcag acctcttcat cgttttgaca ggtgtagatt atgtatttgt
    16861 taactacaac aagccaaacc aggaaaaatt ggaacatgtg aatgttgccc agctggaaga
    16921 atatatcaaa caagatcagt ttgcaccagg tagcatgctt ccaaaagtag aagcagctat
    16981 cgcttttgtc aatggtcgtc cagaaggaaa agcagttatt acttcccttg aaaatctagg
    17041 cgccttgatt gaatctgaaa gcggaacaat tattgaaaaa ggataagttg ttttactaat
    17101 aagatgtatt ctatttctag tatctttata tcaaattaga aattattctt gaaaacatgt
    17161 acaatatttc aaaagatact agttttttag actttaatat ggtaaaacaa atatagatgg
    17221 aaagcgtttt cttaaatgtt tatttaagaa agtagttggt tttttacact ttgttagaca
    17281 tcaggaggaa aaacaaatga gtgaaaaagc taaaaaaggg tttaagatgc cttcatctta
    17341 caccgtatta ttgataatca ttgctattat ggcagtgcta acttggttta tccctgcggg
    17401 ggcctttata gaaggtattt acgagactca gcctcaaaat ccacaaggga tttgggatgt
    17461 cctcatggca ccgattcggg ctatgctagg tactcatcca gaggaaggtt cgctcattaa
    17521 agaaacgagc gcagcgattg atgtagcctt cttcatcctt atggttggtg gtttccttgg
    17581 cattgtcaac aaaactggtg ctcttgacgt agggattgcc tctatcgtga agaagtataa
    17641 gggccgcgaa aaaatgttaa ttttggtatt gatgcctttg tttgccctcg gtggtacaac
    17701 ttatggtatg ggtgaagaaa caatggcctt ctatccactc cttgtgccag ttatgatggc
    17761 cgttggtttt gatagcctga ctggtgttgc aattattttg ctcggttctc aaatcggctg
    17821 tttggcatct actctgaatc catttgcgac aggtattgct tcagcgactg cgggagttgg
    17881 tacaggggac ggtatcgtac ttcgtctgat cttctgggtt accttgactg ctcttagtac
    17941 ttggtttgtt taccgttatg cggataagat tcaaaaagat ccgactaagt cactggttta
    18001 tagtactcgc aaagaagatt tgaaacactt taacgtagaa gaatcttcat ctgtagaatc
    18061 tacacttagc agcaaacaaa aatcagttct cttcttattt gtgttgacat tcatcttgat
    18121 ggtattgagc ttcattccat ggacagacct tggcgttacc atttttgatg actttaatgc
    18181 ttggttgact ggtcttccag ttattggtaa tattgtcggt tcatctactt ctgcactagg
    18241 tacttggtac ttcccagaag gcgccatgct ctttgccttt atgggtatcc tgattggtgt
    18301 tatttatggt cttaaagaag ataagattat ctcttccttc atgaatggtg ctgctgactt
    18361 gctcagtgtt gccttgatcg tagcgattgc tcgtggtatt caagttatca tgaacgacgg
    18421 tatgattacc gatacaatcc tcaactgggg taaagaaggc ttgagcggtc tatcttcaca
    18481 agtctttatc gttgtaactt atatcttcta tctacctatg tcattcttga tcccatcttc
    18541 atctggtctt gccagcgcaa ctatgggtat catggctcca cttggagaat ttgtaaatgt
    18601 ccgtcctagc ttgattatca ctgcttacca atctgcttca ggtgtcttga acttgattgc
    18661 accaacatct ggtattgtga tgggagctct tgcacttgga cgtatcaaca ttggtacttg
    18721 gtggaaattc atgggcaaac tcgtagtcgc tattattgta gtgaccatcg cccttcttct
    18781 ccttggaacc ttccttccat tcctataaaa tagtgagtga ggtgattcca tgaaaataga
    18841 tataacaaat caagttaaag atgaatttct tatatcatta aaaaccttga tttcctatcc
    18901 ttcagtactc aatgaaggag aaaatggaac accttttgga caagcaatcc aagatgtcct
    18961 agaaaaaact ttagagattt gtcaagacat aggtttcact acctatcttg accctaaagg
    19021 ttattacgga tatgcagaaa tcggtcaggg agcagagctt ctggccattc tctgtcattt
    19081 ggatgttgtt ccatcaggtg atgaagcaga ttggcagaca ccgccatttg aagcaactat
    19141 caaagacggc tgggtattcg gacgtggtgt ccaagatgat aaaggccctt cgctcgcagc
    19201 tctctatgca gtaaaaagct tgctggacca aggtattcag ttcaaaaagc gcgtacgctt
    19261 tatctttggt accgatgagg aaaccctctg gcgctgcatg gcacgctaca ataccatcga
    19321 agaacaggcc agcatgggct ttgcacctga ctcatctttt cctctgacct atgctgaaaa
    19381 agggcttcta caggtcaaac tttatggccc tggatcggat caactagagc ttgaagtagg
    19441 aggcgccttt aacgttgtac cagacaaggc caactaccaa ggtcccctct atgaacaggt
    19501 ttgtaacggt ctcaaagaag ctggttatga ttaccaaacc actgaacaaa ccgtaacggt
    19561 tctcggagtg ccaaagcatg ctaaggatgc tagtcaaggt atcaatgctg tcatccgact
    19621 agctaccatt cttgctcctc tccaagaaca ccctgctctc agttttcttg caacacaagc
    19681 aggtcaagac ggcacaggaa gacaaatctt tggtgatata gcagatgaac cttctggtca
    19741 cctatccttt aatgtcgcag gtctcatgat caatcatgaa cgttctgaaa tccgtattga
    19801 cattcggact cctgtcttag ctgacaagga agaactagta gagttgctta caagatgtgc
    19861 acaaaactac caactccgct acgaagagtt tgactatcta gcgcctctat acgtcgcaaa
    19921 agacagtaaa ctcgttagca cactgatgca aatctaccaa gaaaagactg gcgataacag
    19981 tcctgctatt tcatccggtg gtgccacttt tgctcgcacc atgccaaatt gtgtagcctt
    20041 cggcgcctta ttcccaggag cgaagcagac agaacatcag gcaaatgaat gtgccgttct
    20101 agaagatttg taccgtgcta tggatattta tgccgaagcc atctatcgac ttgcaactta
    20161 atcaggcaac tgtttctaca aaaaaaaatc gaccgattaa tgaactgcac cccaaaagtt
    20221 agacagaata aatctaactt ttggggtgtt ttattatgaa attgaattat gaagataaag
    20281 ttcagatcta tgaactaaga aagcaaggac aaagcttcaa acagctttca aaaagatttg
    20341 gtgtggatgt ttctggtcta aagtcatctg aatctttgag atgagcttta taaatcgctt
    20401 ttttcagttt ttgcactggt gtttcgataa actcaaactt tttagccgtg gtattgcctg
    20461 attttatagt atattgaaac tagaatagta cacctctact tctaaaacat ttttagaaat
    20521 cgatttgact gtcctgatcg atttgtcctg ttcttatttc attttactat atttgagcca
    20581 cttcgtcttt aacggcttta ttcataagct cttgtaattt ttctttacta tcaattactt
    20641 ctgattttcc gttgtaattt attgtaatag gttttaactt acctaatttc tcgacacgct
    20701 cattaatttg atcttttttg aaggctgcat atgtttttcc taagattttt tcaaaaatat
    20761 atttatcaga tagcggtttg tcttcttctt cagcttggtt tttgtattaa tttgaaacat
    20821 aaggaacaaa tccttcatag taacctaatg ctcccataag ttcaaaagct tgttttctaa
    20881 ttcaaaccat tgcaactcag atttcagctt ttcagataaa tcctgctcat ccaaataatg
    20941 acttgaaatt agtgctgaac tcgtttctgt atcctgtaca ggctgatcac ccataccagc
    21001 aaaaaataaa ctcgttccta gcaagaccga acaagctcct attgcatatg gcctcaaaga
    21061 aaaacgctgc tttctctcaa attgaaattc tttcatccca tctcccatca ttcattatta
    21121 ctgtatattt tgtatatcag aaatagtttg tattcacaaa tctttctagt tattccctta
    21181 tcattcctaa ttaagggagg taacatacaa taatttttag ttaaatgtat atctatgttt
    21241 tttgtttttc ttaataaacg caatacaaaa agagcctgtt gccaagctct ttgtactcaa
    21301 tgaaaatcaa atagcaaact aggaaactag ccacaggttg ctcaaaacac cgttttgagg
    21361 tagtagataa gactgacgaa gtcagctcaa aacactgttt tgaggttgca gatagaactg
    21421 acgaagtcag ctcaaatata cggcaaggcg acgctgacgt ggtttgaaga gattttcgaa
    21481 gagtattagt ctattatttc ttctcagcgc gaagggctga caagatttgt gttcggatat
    21541 catccacacc atttggcgta tttggtaaaa agatggtttg atttccttta gaggcaaagg
    21601 tattcaaggt atccaaatac tggttggtca agaggataga catgatttgt tcttctgtca
    21661 tgccaacatt ggcttccttg agttcggtga tagactctgc caatccatcc acaatcgcct
    21721 tacgttgttg ggcaatcccc acaccatgaa ggcggtcttt ttctgcttct gcttcagctg
    21781 cagtgacaat tttaatcttg tcagcttccg ccaattcttg tgctgcgacc cgcttacgtt
    21841 gcgccgcatt gatttcattc atggattgct taacttctgc atccggttcg actttggtaa
    21901 tcaaggtttt cacgataatg tagccgtaag tggtcatttc ttctgctact tggtgttgaa
    21961 cttcaagggc aatctcatct tttttctcaa acaattcatc caaggttaat tttggaacag
    22021 aagagcgaag agcatcttcg atataagatt taatctgaga ttctggacgt atgagtttat
    22081 agtaagcatc tgtcacgctc tgctcgttga cacggtactg agtcgctaca ttcatcataa
    22141 cgaacacatt gtccttggtc ttagtctcaa ccacaatatc actttgcaac aagcgcaact
    22201 gaatccgtgc tgcaatcgag tcaatcccaa aaggcaagcg aatatgaata ccgctattag
    22261 caaccttttg gtatttccca aagcgttcaa taatcgccac cgactgctga cgaaccacat
    22321 aaactgtact cagtgtgact atcaccaata ggagcacaca aacaatcaga aaaatcatga
    22381 aaaatattgc cataatggaa cctccacaag tatttttcta gtattatagc acatttaaag
    22441 aaggctgtgc cgtttttact gcgatttttc ctgaaatgtc aataattaga ggtgaattgt
    22501 cctattgtcg tccaatctct tgctaaaata actctttata aaaggcaatc gtttcttcta
    22561 aggttggcat aaatggattt cctggtgcgc aggcatcaat caaggcattc ttagaaaggt
    22621 attcaaagtc gaaatctttt tcttcaatac caagttcagt cagtttctta ggaataccta
    22681 ctgtctcaga aagcttctca atctcagcaa tcgcataatc ggcacattct tgatctgatt
    22741 taccttctac atgaagtccc aaggctttgg caacattgcg gaaagcttct ggtacacgtt
    22801 tagcattttc acgttctata actggtagca acatggcaca gcaaacacca tgtggtaaat
    22861 tatatactgc accgagttgg tgagccattg agtgaacata accaagacca gcattattaa
    22921 agctcatacc accaaggaag atggcattga ccataccttc acgcgcttca atatcatgtc
    22981 cattttctac agcacgagga agatattcct tgataagctc aatagcacca atagacagtt
    23041 tcttggttac atcataagca ccaggtgtta ccaaagcttc aacagcgtga gtcagagcat
    23101 ccataccagt agcagcagtc aaggcttgag gtttggaaag catgagttcc gggtcattga
    23161 cagagataag agcaaggcta ttcttgtcaa ccattaccat cttaaccttg cgttcttcat
    23221 cagtaatcac atagttaata gtgatttctg cagaagttcc tgccgttgta ttgatagcca
    23281 caactggcaa gcctttttta gcagacttat gaagcccttc ataatcctgt ggtcttccac
    23341 catttgtagc catgatagaa atacaactag ctgcatcctg tggagaaccc ccaccaagac
    23401 tgatgataaa atcacatcca tgttcttgca aagcagctac cccatctgtg acatttttac
    23461 aagtagggtt tggctctaca tccctaaaga tgacatattc gattccttct gtatctagcg
    23521 gttttaaaac cttaggtaaa atgtcactgc cttcgatgta cttatctgtc accaaaagtg
    23581 cctttttata gccaagttcc ttgatataag gacccacttc atttacaaca cctttaccaa
    23641 taaggttgac tgccggaaca taaaatgtag ccatataatt ttcctcctgc gcctttgcgc
    23701 tatctattta acatcattat attacttttt gtattcgttt tcaattattt gtgaattgtt
    23761 taacaaatct ttttaaaagg ataggaggga cgtaagttca cctcctatat aaacaagttt
    23821 tatttatgta gtggtcccaa caactgacat gcacgatagt ctgctgattc tagatcttct
    23881 gttccaaata aggaccaatt tttaggtcta aagatatctt cctcaggtac attatgcata
    23941 ttgacaggaa ttctcaacat agaagccaag gtaatcaagt ctgctccaat gtgtccatat
    24001 gttatggctc cgtgattagc tccccaatta ttcatgacgt catagacaga cttgaaagca
    24061 ccttttcctg tcaaacgtgg agcaaaccaa gtagttggcc atcctggatc tgtacgatta
    24121 tctaaagtat ggtgaacatc ttcaggaagt tcaagtgtat aaccttctgc aatttgtagc
    24181 actggaccaa ccccttttag aagattgaga cgtaccattg ttactggcat atcccccttc
    24241 gtcaagaaac gagttgagaa tcctcctcca cggaagtatt cgcggtttgc tggtgggaag
    24301 tctgtatttt caagcatagc ctgcacttca ctttcttcca actcccagaa tggtttcata
    24361 acaggtttgc catctcgagt agcttgacct gtaccatcca atgtacaaga accagagttg
    24421 attagatgta agaagccagc tgcagcacga ccctctaaag tatgtcccgt tacacgttta
    24481 acagcctctg ggctccaata agtacgcaca tcagcaaaga tttgtggagt atttgttaat
    24541 agataattaa agagcataga cacaccattt agtgaatcat tctctgtcgc aaatacaaat
    24601 ggttttcgaa taccattcca gtcaaactga gtattgagga aagtttccat aaaatctcca
    24661 tttggaaaat ggtctgtcca ctgacgttga ccttggaaac cagctactaa agcatggtga
    24721 ccaaccgctt cttcctcaaa accaagttca gcaagtcttg ggttaccaac cattaagtca
    24781 cgtccaatca tgaacatctt aataacaaat tcccattgtt tttctttctc ttctttagaa
    24841 agaatcaaat cctcacgatt tcggtcaacc ccttctttga tatgttcttt tacccaaacc
    24901 atagcacgtt cgaactcttc tgggtcataa ataccacggt ccatacggcg cgtgaactcc
    24961 gtcatatcta ccgattcatt tcgcattcct aagtattctt ggaagaaatc tggatttaca
    25021 atagaaccgc caatccccat cgaaacacta cccattgata ggtaagcagt gtctctcatc
    25081 aagccagttg caagagctgc acgcgcataa cgtaaaagtt tttctttgac atcttctgga
    25141 atatctgtat cattagcttc ctgaacatct ctaccataaa tcccaaaggc tggaatccct
    25201 ttttgagcat gtgaagctag tacagctgca agatagacag ctcctgggcg ttctgtccca
    25261 ttaaatcccc aaatagcatg aggaatatct ggagacatat ccatagtttc actaccataa
    25321 caccagcatg gtgtaactgt aattgttgcg caaacatttg attttttaaa caactcatgg
    25381 gaagctgcag cctctggaac acgaccaatg gtagatggag aaatcacaca ttccacaggt
    25441 tccccatctg gatatttcaa tgtgcttgaa atcaaatctg ccacactttt agccatgttc
    25501 attgtttgta cttcaagtga ttcgcgtaca ccttgacgac gaccatcaat agtcggacga
    25561 atcccaatac gtggatgttg aatcatacta ttttcctctt atttttctgt ttctttcata
    25621 ctaccgatga taatttttaa aattacttat aagtataaac ctctacctct gccaaactta
    25681 aaggaattcc tgcgtttctc aaagaaattc taaccttttt tcccttcagc ccttttaagt
    25741 ctatggatag attattgctt tctaaactgt caatatgttg tttaa
//
LOCUS       DAVMJI010000030        23980 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.030, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000030 DAVMJI010000000
VERSION     DAVMJI010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23980
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.030"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            40..636
                     /locus_tag="VYR58_001515"
     CDS             40..636
                     /locus_tag="VYR58_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3622646.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            617..1108
                     /locus_tag="VYR58_001516"
     CDS             617..1108
                     /locus_tag="VYR58_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622647.1"
                     /translation="MKFQTNNSLYKLMNLIIYLFLLYLFIDLLMKSGILDEQIDKLSE
                     LSNLFTIKIETILTVISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITL
                     SFSILLCYLFNPSDIKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSII
                     NSF"
     gene            1488..3641
                     /locus_tag="VYR58_001517"
     CDS             1488..3641
                     /locus_tag="VYR58_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV3622648.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKEQKNGLFSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3654..5003
                     /locus_tag="VYR58_001518"
     CDS             3654..5003
                     /locus_tag="VYR58_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV3622649.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQGGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            5173..5880
                     /locus_tag="VYR58_001519"
     CDS             5173..5880
                     /locus_tag="VYR58_001519"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV3622650.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            5937..9662
                     /locus_tag="VYR58_001520"
     CDS             5937..9662
                     /locus_tag="VYR58_001520"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV3622651.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLSIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGVIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLSELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLSYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9755..11197
                     /locus_tag="VYR58_001521"
     CDS             9755..11197
                     /locus_tag="VYR58_001521"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV3622652.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FYDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11234..12256
                     /locus_tag="VYR58_001522"
     CDS             11234..12256
                     /locus_tag="VYR58_001522"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV3622653.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12253..12798
                     /gene="purN"
                     /locus_tag="VYR58_001523"
     CDS             12253..12798
                     /gene="purN"
                     /locus_tag="VYR58_001523"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV3622654.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12882..13391
                     /locus_tag="VYR58_001524"
     CDS             12882..13391
                     /locus_tag="VYR58_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV3622655.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13416..14963
                     /gene="purH"
                     /locus_tag="VYR58_001525"
     CDS             13416..14963
                     /gene="purH"
                     /locus_tag="VYR58_001525"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV3622656.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     NDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAANKYGLTMVFT
                     GVRHFRH"
     gene            15085..16347
                     /gene="purD"
                     /locus_tag="VYR58_001526"
     CDS             15085..16347
                     /gene="purD"
                     /locus_tag="VYR58_001526"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV3622657.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTVATVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16750..17238
                     /gene="purE"
                     /locus_tag="VYR58_001527"
     CDS             16750..17238
                     /gene="purE"
                     /locus_tag="VYR58_001527"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV3622658.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            17225..18316
                     /gene="purK"
                     /locus_tag="VYR58_001528"
     CDS             17225..18316
                     /gene="purK"
                     /locus_tag="VYR58_001528"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV3622659.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAKVTVAPYKVVTSSQDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVQA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAQLPAIKLHAPAVMLNVLGQHVEAAEKYVAENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18326..18553
                     /locus_tag="VYR58_001529"
     CDS             18326..18553
                     /locus_tag="VYR58_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV3622660.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            18616..19914
                     /gene="purB"
                     /locus_tag="VYR58_001530"
     CDS             18616..19914
                     /gene="purB"
                     /locus_tag="VYR58_001530"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV3622661.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19969..23895)
                     /gene="strH"
                     /locus_tag="VYR58_001531"
     CDS             complement(19969..23895)
                     /gene="strH"
                     /locus_tag="VYR58_001531"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV3622662.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDKAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEILSQPAPAEESK
                     ALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
BASE COUNT         6560 a         4705 c         5656 g         7059 t
ORIGIN      
        1 tttattaatt ttagcagcgt tgatagaggg aattaaatta tgaaaattga aaatgaatct
       61 aaaagttatg ataaatgtat attgaaaaat atatcactag agattgataa gggaatttac
      121 agagttgaag gagagaatgg ttcaggaaag agcacccttc tacaactttt agctgggcta
      181 gagacttttg atagtggttt aaagaattgt gtctccaaag atgtactata ccttgatacc
      241 aatcagcttg gggttgttcc atttactata gaagaaaatt tgcagttgtt gtgtgattct
      301 tttcaaatcc atctatcatt tgaggataaa gaacaaatta atactttttt tgataataaa
      361 atcggagata actatatgac agcatctact ggaacaaaat tcaaattagg cttatcctta
      421 atttttgcta aaaattggga ttatattttt attgatgaga ctttatcaac agtggatgca
      481 agaagtattg atatgattgc taaacgctta atttccatga aagaaagctc tactattata
      541 tatgtatctc ataatttatt gaatcaagaa ttgattagca aatctcaaag gattttaata
      601 gaggaaggac gggtttatga aatttcaaac aaataatagt ttatacaaat taatgaatct
      661 gattatttat ctttttcttt tatatttgtt tattgattta ctgatgaagt cgggaatttt
      721 agatgaacaa attgataaat tatctgaact atctaatctt tttacaatta aaatagaaac
      781 aatattgaca gtgatttctg ttgttttcac atttatagca actcttattg aatatggatt
      841 ttctctcttt ctgattacat tattttttga taagaataag aggaactttg gagatattct
      901 tttatctaaa aatataacct taagttttag cattttactt tgttatttat ttaatccatc
      961 ggatataaag tttgcctatt tcagcgtatt gacagtatta ctaattggga taacaaatta
     1021 tgcgagattt aaaaatttaa gattgacagt agtgttttct gtaccatttt tatttaatgc
     1081 tataatgtct attataaata gtttttagaa atactaaaat ttttttcttt acttaataat
     1141 gatatgaaat catttcggtt ttgttaactt gtaattctta tattttctag gtagaacgtt
     1201 tgttctgcct atttttttat ccaaaaagtg cagttgggag ggagataggc tcatttggga
     1261 aggaagtcca gtttttgttt agtgattggg gtaagatagt tgttatcaga tgagtttata
     1321 ctcttcgaaa atcaaattca aaccacgtca acgtcgcctt gccgtatata tgtgactgac
     1381 ttcgtcagtc ctatctacaa cctcaaaaca gtgttttgag cagcctgcgg ctagtttcct
     1441 agtttgctct ttgattttca ttgagtatta gggaaaagga gatgaatatg aaatttggga
     1501 aacgtcacta tcgtccgcaa gtggatcaga tggactgcgg tgtagcttca ttagccatgg
     1561 tttttggcta ctatggtagt tattattttt tggctcactt gcgagaattg gctaagacga
     1621 ccatggatgg gacgacggct ttgggcttgg tcaaggtggc agaggagatt ggttttgaga
     1681 cgcgagccat taaggcggat atgacgcttt ttgacttgcc ggatttgact tttccttttg
     1741 ttgcccatgt gcttaaggaa gggaaattgc tccactacta tgtggtgact gggcaggata
     1801 aggatagcat tcatattgcc gacccagatc ctggggtgaa attgactaaa ctgccacgtg
     1861 agcgttttgc ggaagaatgg acaggagtga ctctttttat ggcacctagt ccagactaca
     1921 agcctcataa ggaacaaaaa aatggtctgt tctcttttat ccctatatta gtgaagcagc
     1981 gtggcttgat tgccaatatc gttttggcaa cactcttggt aaccgtgatt aacattgtgg
     2041 gttcttatta tctgcagtct atcattgata cctatgtgcc agatcagatg cgttcgacac
     2101 tagggattat ttctattggg ctagtcatcg tctacatcct ccagcaaatc ttgtcttacg
     2161 ctcaggagta tctcttgctt gttttggggc aacgcttgtc gattgacgtg attttgtcct
     2221 atatcaagca tgtttttcac ctccctatgt ccttctttgc gacacgcagg acaggggaga
     2281 tcgtgtctcg ttttacagat gctaacagta tcatcgatgc gctggcttcg accatccttt
     2341 cgattttcct agatgtgtca acggttgtca ttatttccct tgttctattt tcacaaaata
     2401 ccaatctctt tttcatgact ttattggcgc ttcctatcta cacagtgatt atctttgcct
     2461 ttatgaagcc gtttgaaaag atgaatcggg ataccatgga agccaatgcg gttctgtctt
     2521 cttctatcat tgaggacatc aacggtattg agactatcaa gtccttgacc agtgaaagtc
     2581 agcgttacca aaaaattgac aaggaatttg tggattatct gaagaaatcc tttacctata
     2641 gtcgagcaga gagtcagcaa aaggctctga aaaaggttgc ccatctcttg cttaatgtcg
     2701 gcattctctg gatgggggct gttctggtca tggatggcaa gatgagtttg gggcagttga
     2761 ttacctataa taccttgctg gtttacttta ccaatccttt ggaaaatatc atcaatctgc
     2821 aaaccaagct tcagacagcg caggttgcca ataaccgtct aaatgaagtg tatctagtag
     2881 cttctgagtt tgaggagaag aaaacagttg aggatttgag cttgatgaag ggagatatga
     2941 ccttcaagca ggttcattac aagtatggct atggtcgaga cgtcttgtcg gatatcaatt
     3001 taaccgttcc ccaagggtct aaggtggctt ttgtggggat ttcagggtca ggtaagacga
     3061 ctttggccaa gatgatggtt aatttttacg acccaagtca aggggagatt agtctgggta
     3121 gtgtcaatct caatcagatt gataaaaaag ccctgcgcca gtacatcaac tatctgcctc
     3181 aacagcccta tgtctttaac ggaacgattt tggagaatct tcttttggga gccaaggagg
     3241 ggacgacaca ggaagatatc ttacgggcgg tcgaattggc agagattcga gaggatatcg
     3301 agcgcatgcc actgaattat cagacagaat tgacttcgga tggggcaggg atttcaggtg
     3361 gtcaacgtca gagaatcgct ttggcgcgtg ctctcttgac agatgcgccg gtcttgattt
     3421 tggatgaggc gactagcagt ttggatattt tgacagagaa gcggattgtc gataatctca
     3481 tggctttgga caagaccttg attttcattg ctcaccgctt gactattgct gagcggacag
     3541 agaaggtggt tgtcttggat cagggcaaga ttgtcgaaga aggaaagcat gctgatttgc
     3601 ttgcacaggg aggcttttac gcccatttgg tcaatagcta gaaagaggag aggatgaaac
     3661 cagaattttt agaaagtgcg gagttttata atcgtcgtta ccataatttt tccagtagtg
     3721 tgattgtacc catggccctt ctgctcgtgt ttttacttgg ctttgcaact gttgcagaga
     3781 aggagatgag tttgtccact agagctactg tcgaacctag tcgtatcctt gcaaatatcc
     3841 agtcaactag caacaatcgt attcttgtca atcatttgga agaaaataag ctggttaaga
     3901 agggggatct tttggttcaa taccaagaag gggcagaggg tgtccaagcg gagtcctatg
     3961 ccagtcagtt ggacatgcta aaggatcaaa aaaagcaatt ggagtatctg caaaagagcc
     4021 tgcaaggagg ggagaaccac tttccagagg aggataagtt tggctaccaa gccacctttc
     4081 gcgactacat cagtcaagca ggcagtctta gggctagtac atcgcaacaa aatgagacca
     4141 tcgcgtccca gaatgcagca gctagccaaa cccaagccga aatcggcaac ctcatcagtc
     4201 aaacagaggc taaaattcgc gattaccaga cagctaagtc agctattgaa acaggtgctt
     4261 ccttggccgg tcagaatcta gcctactctc tttaccagtc ctacaagtct cagggcgaag
     4321 aaaatcccca aactaaggtt caggcagttg cacaggttga agcacagatt tctcagttag
     4381 aatctagtct tgctacttac cgtgtccagt atgcaggttc aggtacccag caagcctatg
     4441 cgtcagggtt aagcagtcaa ttggaatccc ttaaatccca acacttggca aaggttggtc
     4501 aggaattgac ccttctagcc cagaaaattt tggaggcaga gtcaggtaag aaggtacagg
     4561 gaaatctttt agacaagggg aaagttacgg cgagtgagga tggggtgctt catcttaatc
     4621 ctgagaccag tgattctagc atggttgcag aaggtgccct actagcccaa ctttatccat
     4681 ctttggaaag agaagggaaa gccaaactca cagcttatct aagttcaaaa gatgtagcaa
     4741 gaatcaaggt cggtgattct gttcgctata ctacgactca tgatgccggg aatcaacttt
     4801 tcctagattc tactattaca agtattgatg cgacagctac taagactgag aaagggaatt
     4861 tctttaaaat cgaggcggag actaatctaa cttcggagca ggctgaaaaa cttaggtatg
     4921 gggtggaagg ccgtttacag atgattacgg gcaagaaaag ttatctacgt tattatttgg
     4981 atcaattttt gaacaaagag taatgttcgt gtttttagag ttaaataatt tttaaactgt
     5041 gagaaagatt cttcttgcag ttttttcttt acaatttttg aaaagcatct gctatttatt
     5101 cggttaaatt cttgtgtttt ttggtttttt gtggtaaaat gtgctcaagt aatacgaaag
     5161 gcgaacttta aaatgtcaaa acaattgatc tattcgggaa aagctaaaga tatctataca
     5221 actgaggatg aaaatcttat tatttcaact tacaaggacc aggcgactgc tttcaacggt
     5281 gtcaagaagg agcagattgc aggtaaggga gtcttgaata atcagatctc atcttttatt
     5341 tttgagaaat taaatgcggc tggtgtggcg actcactttg tggagaaact ttcagacacg
     5401 gaacaactca ataaaaaggt taagattatt cctttggaag tcgtgctccg caactatact
     5461 gctggttcct tttcaaaacg ttttggtgtg gatgagggaa tcgccttgga gactccgatt
     5521 gtcgaatttt actataaaaa tgatgatttg gatgatccat ttatcaatga tgagcatgtg
     5581 aaattcctac agattgcgga tgaccagcag attgcctact tgaaggaaga aacgcgtcgt
     5641 atcaatgaac tattgaaagt ctggtttgct gagattgggc ttaaattgat tgactttaag
     5701 ctagagttcg gttttgacaa ggatggcaag attatcttgg cagacgaatt ttcaccagat
     5761 aactgccgct tgtgggatgc tgatggcaac cacatggata aggatgtttt ccgtagagga
     5821 ttgggagaac taaccgacgt ttacgaaatt gtctgggaaa agttgcaggg tttaaaataa
     5881 caacctcaag gctgtttggg aatattgcaa gagctgaaat aaaggaataa gaattgatgg
     5941 ataaacgtat ttttgttgaa aaaaaggctg attttcaggt caagtcagag agtttggtta
     6001 gagagctcca gcacaacttg ggactgtcaa gcttgaaaag tattcgtatt gtgcaagtat
     6061 atgatgtatt tgacttggtt gaggacttgt ttgcacctgc agagaagcac attttctctg
     6121 agcaggtaac cgaccatgtt ttagatgaag tatctgtgca ggcggatctt gctaactatg
     6181 ctttctttgc cattgaaagt ctaccagggc agtttgacca gcgtgcagct tcgtcacagg
     6241 aagccttgct tttgttggga agttcgagtg acgtgacagt caacacagcc caactttact
     6301 tggtgaataa agatattgat gcgactgagt tggaagctgt caaaaactac ctgctcaatc
     6361 cagttgattc tcgtttcaag gatatcacga tagggattgc caagcaggag ttttcagagt
     6421 cagacaagac cattccaaaa ttgcctttct ttgaaagcta tacagcagaa gactttgctc
     6481 gctacaaggc cgaacaaggg atggccatgg aagtggatga tttgctctct atccaagact
     6541 actttaagtc aatcgggcgc gtgccaactg agactgaact caaggttttg gacacttact
     6601 ggtctgacca ctgccgtcat acgacttttg agacagagtt gaaacacatc gacttttcag
     6661 cttctaaatt tcaaaagcaa ttgcagtcaa cctatgacaa gtatattgcc atgcgcgagg
     6721 aattaggtcg gtctgaaaaa ccacaaacct tgatggatat ggcgactatt ttcggtcgtt
     6781 atgagcgtgc taatggacga ttggatgata tggaagtctc tgacgaaatc aatgcctgct
     6841 cagttgaaat tgaagtggac gttgatggtg tcaaggaacc ttggctcctc atgtttaaaa
     6901 acgaaaccca caaccatcca acagaaattg agccatttgg tggagcggct acctgtatcg
     6961 gtggagttat tcgtgatccg ttgtcaggcc gttcctatgt ttaccaagcc atgcgtattt
     7021 caggtgctgg tgatattaca gcaccgattt cggaaactcg tgctgggaaa ttgccacaac
     7081 aagtcatttc taaaacagca actcatggtt attcttcata tggtaaccag attgggcttg
     7141 ccacaaccta cgttcgtgaa tacttccacc caggctttgt agctaaacgt atggaacttg
     7201 gtgccgttgt tggtgcggct cccaagggca atgttgtccg tgaaaaacct gaagcaggtg
     7261 atgtgatcat ccttctcgga ggtaaaacag gtcgtgatgg tgtcggtggt gcgacgggct
     7321 cttctaaggt tcaaacagtt gagtctgtag agactgctgg tgctgaggtt caaaaaggaa
     7381 atgccatcga agaacgcaag attcagcgcc tcttccgtaa tggcaatgtc actcgtctga
     7441 tcaagaagtc caatgacttt ggggcaggcg gtgtctgtgt ggctatcggt gaattggcag
     7501 acggtcttga aatcgacctc aacaaggtgc ctcttaaata ccagggcttg aatggtacag
     7561 aaattgccat ctctgaatca caagaacgga tggcggtcgt ggttcgtcct gaagatgtgg
     7621 ataccttcgt tgccgaatgt aacaaagaaa atattgatgc tgttgtggtg gcgacagtaa
     7681 ctgaaaaacc aaatcttgtc atgcactgga atggtgagac aatcgttgac ttggagcgtc
     7741 gtttccttga caccaatggt gtgcgcgtgg ttgtcgatgc caaagttgtg gacaaggatg
     7801 tcaaactccc agaagagcgt caaacatctg ctgaaacact ggaatcagat acccttacgg
     7861 ttctatctga cctcaaccat gcaagtcaaa aaggattaca gactatcttt gactgctctg
     7921 ttggacgctc aacggttaat cacccacttg gtggccgtta ccaactcaca ccaactgagg
     7981 catctgtgca gaaattgcca gttcaacacg gtgtgactca tactgcgtcg gtcattgctc
     8041 aaggtttcaa cccatatgta gctgaatggt ctccatacca cggtgctgct tatgcggtta
     8101 tcgaagcaac cgctcgtttg gttgctgctg gtgccaactg gtccaaggct cgtttctctt
     8161 accaagagta tttcgagcgt atggataaac aagcagagcg tttcggtcag ccagtagctg
     8221 ctcttctagg ttctattgaa gcacaaattc agcttggctt gccatctatc ggtggtaagg
     8281 actccatgtc tggtaccttt gaagaattga ccgttccgcc aaccttggtt gcctttgggg
     8341 tgacgacggc agatagccgt aaggtgctct ctccagaatt taaagctgtt ggggaaaata
     8401 tctactacat cccaggtcaa gccctctctg cagagattga ttttgacttg attaagaaaa
     8461 attttgctca gtttgaagcc atccaagctg accataaagt gacatctgca tcagctgtca
     8521 aatacggtgg tgtagttgaa agtttggctc ttgctacctt tggaaactat attggtgcag
     8581 aggtgacctt gtctgaactt aaaacagctt tgacagctca attaggcggc tttgtcttca
     8641 catctcctga agaaattgct ggagtagaga agattggaca aacgaaagca gactttacac
     8701 tgactgtcaa cggtgtgaag ctagatggac acaagcttga cagtgcattt caagggacat
     8761 tggaagaagt ttacccaaca gaatttaccc aagcaaaaga actagaagaa gtaccagctg
     8821 tggcatcaga tgttgtgatt aaagccaaag aaaaggttga aaagcctgtg gtttacatcc
     8881 cagtctttcc aggaaccaac tcagaatatg attcagctaa ggccttcgaa aaagaaggtg
     8941 cagaggtcaa tttggtgcca ttcgtgacct tgaatgaaga agctattgtc aagtcagttg
     9001 aaactatggt tgacaatatc gacaagacta atattctctt ctttgccggt ggattctcgg
     9061 ctgcggatga accagatggt tcagctaagt ttatcgtcaa tatcctgctt aatgaaaaag
     9121 tgcgtgtggc tattgatagc tttatcgccc gtggtggttt gattatcggt atttgtaatg
     9181 gattccaagc cttagtcaaa tcgggtctcc tatcatacgg aaactttgaa gatgctaaca
     9241 gtactagtcc aaccctcttc tacaatgatg ccaaccaaca cgtggccaag atggtggaaa
     9301 ctcgcattgc caataccaac tcaccatggt tggctggtgt gcaagtgggc gatatccacg
     9361 ctattcctgt ttcgcacggt gaagggaagt ttgtcgtgac ggctgaggaa tttgcagagc
     9421 tccgtgacaa tggacaaatt ttcagccaat acgttgactt taacggtaaa ccaagtatgg
     9481 attctaagta caatccgaat ggttctgtcc atgccatcga aggaattacc agcaagaatg
     9541 gtcaaatcat cggtaagatg ggccactcag aacgttatga ggatggtctt ttccaaaata
     9601 tcccaggcaa taaagaccaa cacctgttcg catcagcggt taaacatttc actggaaaat
     9661 aagacttaca gattttctaa tagatagtat cagtaatgta aaagtcatgt aaatctagct
     9721 cttgatgatt acaaatgaaa attaggtata aaaaatgaca tacgaagtaa aatctcttaa
     9781 tgaagaatgt ggtgttttcg gtatttgggg acatccagat gctgctaagt tgacctattt
     9841 tggactccac agtcttcaac accgtggtca ggagggggca ggaatcctct ccaatgatca
     9901 aggacaactg aagcgccatc gtgacatggg gcttttatca gaagttttca gaaatccagc
     9961 taatttggat aaattgacag gagctggtgc gattgggcat gtgcgttatg cgactgctgg
    10021 cgaagcttct gtagataaca tccagccctt cctcttccgt ttttacgata tgcagtttgg
    10081 cttggctcat aatggaaatc tgaccaatgc agcctctctc aagaaagaac tggaacaaag
    10141 aggagcaatt ttcagcgcga cttcggactc tgaaatcttg gctcacctca ttcgtcgcag
    10201 tcataatcct agcctgatgg gcaaaatcaa ggaagcgctc agccttgtca aaggtggttt
    10261 tgcctatatc ttgctgtttg aggacaagtt gattgcggct cttgacccaa atggattccg
    10321 accgctttcg attggtaaaa tggctaatgg agcagtagtc gtttcctctg aaacctgtgc
    10381 ttttgaggtc attggtgccg agtggattcg tgatttgaag ccaggtgaga ttgtgatcat
    10441 tgatgacgag ggcattcagt atgatagcta tacagatgat acccagttgg cgatttgttc
    10501 tatggagtat atctactttg ctcgccctga ttctaatatc cacggtgtca atgtccatac
    10561 ggcacgtaag agaatgggag cacaattggc gcgagaattt aagcatgagg cagatattgt
    10621 agttggtgtg cccaattctt ccctaagcgc ggctatggga tttgcggaag aatcaggctt
    10681 accaaatgaa atgggtctga tcaaaaacca atacacccag cgaactttta tccaaccgac
    10741 tcaagaattg cgggagcaag gggtgcggat gaaactgtct gctgtttcgg gtgttgtcaa
    10801 aggcaaacgt gtggtcatgg tggatgattc cattgtacgt ggaacaacct ctcgtcgtat
    10861 cgttcagctc ttgaaagaag cgggtgcgac tgaggttcac gttgccattg gaagtcctgc
    10921 actagcgtat ccatgtttct acgggattga tatccagacc cgtcaggagc tgattgcagc
    10981 caatcatacg gtcgaagaaa ctcgccaaat cattggtgcg gacagtctga cttatctttc
    11041 aattgatggc ttgattgagt cgattggtat cgaaacagat gcgccgaacg gtggtctctg
    11101 tgtcgcttac tttgacggtg actacccaac gcctctttat gactacgaag aagactatcg
    11161 tagaagtttg gaagaaaaga ccagttttta caagtaggcg acagattctc cattaaagaa
    11221 aaggaaaaaa caaatgacaa ataaaaatgc atatgcccag tcgggtgtgg atgttgaagc
    11281 gggttatgaa gttgttgaac ggattaaaaa gcacgtggcc cgtacggagc gtgcaggtgt
    11341 catgggagct cttggtggct ttggtggtat gtttgacctt tccaagactg gggttaaaga
    11401 acccgtcttg atttcaggga ctgacggtgt cggaaccaag ctcatgttgg ctatcaagta
    11461 cgacaagcac gataccatcg ggcaggactg tgtggccatg tgtgtcaacg acatcattgc
    11521 tgcaggtgcg gaacccctct attttctcga ctacgtagcg acagggaaga atgaaccagc
    11581 taagctagaa caagtggttg ctggtgtggc agaaggttgt gtgcaggctg gtgctgccct
    11641 catcggtggg gaaacggctg aaatgccggg catgtacggc gaagacgact atgacttggc
    11701 tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt gacggttcaa aggtggtaga
    11761 gggagatgtt cttctcggac ttgcttcaag tgggattcac tcaaatggtt actctttggt
    11821 tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta ccagaattgg aaggcaagaa
    11881 acttaaggaa gttctacttg agccgactcg tatctatgtc aaggctgtct tgccgctcat
    11941 caaagaagag ttggtcaacg gcattgccca catcacaggt ggtggcttta tcgaaaatgt
    12001 ccctcgtatg tttgcagatg acctagctgc tgaaattgat gaaagcaaag ttccagtgct
    12061 tccaattttc aaagcccttg aaaaatatgg tcagattaaa cacgaagaaa tgtttgaaat
    12121 cttcaatatg ggtgtgggac ttatgttggc ggtcagccct gaaaatgtag agcgtgtaaa
    12181 agaattgttg gatgaagcag tctatgaaat tggtcgcatc gtcaagaaag aaaacgaaag
    12241 tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg gtaatggctc aaattttcag
    12301 gtgattgccg aagaatttcc agtggagttt gtcttttcag accatcgtga tgcctatgtg
    12361 cttgagcgtg caaagcagct cggcgttctg tcctatgctt ttgaactcaa ggagtttgag
    12421 agcaagacag actacgaagc agcccttgtc gaactcttgg aagaacacca gattgacttg
    12481 gtttgcctag caggctacat gaaaatcgtt ggaccaacct tattgtcggc ttatgaaggt
    12541 cggattgtca acattcatcc agcctacttg ccagaatttc caggagctca tgggattgag
    12601 gatgcttgga atgctggcgt gggtcagtct ggtgtgacca ttcactgggt ggattcgggt
    12661 gtggatacag gccaggtcat caaacaggtt cgtgtgccac gactagctga tgataccatt
    12721 gacagatttg aagctcgcat ccatgaagca gagtacaggt tgtatccgga agtagtgaag
    12781 gctctattta cagattgact ttttgatgat tcatatgata tctttgattt taaattggag
    12841 tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt aatgttagaa tctaaaaaaa
    12901 caactcgata tgtattttat gtctatctga tgttattaac ttggggaatc ttatttaagt
    12961 ttgaaacaaa tcctgaattt atagcatttt tcttagctcc aaggtatatc aattggattc
    13021 cattttcaga accactaata gtcgatggaa aaattgtttt tgctgaaatg ttatttaatc
    13081 tgatttcctt tattccatta ggtgtttgtt tccctttgat aaaaactaat ttatctagtt
    13141 taagaatagt cgggacaggt ttcttgatta gtttattgtt tgagtgctta cagtatattt
    13201 tagcaatagg tataacagat ataacggatt tgactttaaa tacgctaggt gtctgtgtag
    13261 gcttactgat ttatcaaatt tttataagag tgttcaaatc acagactaga aaatggatca
    13321 atatcttagg tatgcttagc cttggttttg cttatcttgt tttactgtta ctgcatttaa
    13381 ttggtgttta actaatgatt aaaaaggaga atataatgac taaacgcgtc ttaatcagcg
    13441 tctcagacaa agcgggcatt gttgaatttg cccaagaact caaaaaactt ggttgggaga
    13501 ttatctcaac aggtggaact aaggttgccc ttgataatgc tggggtggat accattgcta
    13561 tcgatgatgt gactggtttc ccagagatga tggatggccg tgttaagact cttcatccaa
    13621 atatccacgg gggtcttctc gctcgtcgtg atttggatag ccacttggaa gcagccaatg
    13681 agaaccaaat tgagcttatt gaccttgtag tggtcaacct ttacccattt aaggaaacta
    13741 tccttaaacc agatgtgact tatgctgatg cagttgaaaa tatcgatatt ggtgggccgt
    13801 ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac agttgtggta gatcctgctg
    13861 actacgctgt ggttttggac gaattggcag caaacggcga aacctcttat gaaactcgcc
    13921 aacgtttagc agccaaagta tttcgtcaca cagcagctta tgacgccttg attgcagaat
    13981 acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact cactttgact tatgacctca
    14041 agcaaccaat gcgttacggt gagaatcctc aacaagacgc ggacttttac cagaaagctt
    14101 tgcctacaga ttactctatt gcttcagcca aacagctcaa cgggaaagaa ttgtcattta
    14161 ataatatccg tgatgcagat gctgctatcc gtatcatccg tgacttcaaa gatagtccaa
    14221 ccgttgtggc tctcaaacac atgaatccat gtggaattgg tcaagctgat gacatcgaga
    14281 ctgcttggga ctacgcttat gagtctgacc cagtatctat ctttggtggg attgtcgtcc
    14341 tcaaccgtga ggtggatgct gcgacagctg agaagatgca cggcgttttc ctcgaaatca
    14401 tcattgcacc aagctatacg gatgaagcgc tagctatttt gatcaataaa aagaaaaact
    14461 tgcgtatcct tgccttgcca tttaatgctc aagaggctag cgaagtggaa gcagaataca
    14521 caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt ggtcaaggaa agcccagctg
    14581 actggcaagt ggtgaccaaa cgtcagccaa ctgagacaga agcgactgct cttgagttcg
    14641 cttggaaggc tatcaagtac gtcaaatcaa atggtattat cgtgaccaac gaccacatga
    14701 cacttggtgt tggtccaggt caaaccaacc gtgtggcttc tgttcgcctt gccattgacc
    14761 aagccaatga tcgtctggac ggggcggtcc ttgcttcaga tgccttcttc ccatttgcgg
    14821 ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat catccagccc ggtggctctg
    14881 tccgtgacca agaatccatc gaagcagcga ataaatacgg cttgactatg gtctttacag
    14941 gtgtgagaca ttttagacat taagaagata aaagggaaga aaacagtttc tttccttttt
    15001 tggcttaaaa tgctaactga aacaagatta aaacgaactt ttttgatata atgttggtaa
    15061 ataattcgca aaagaggttg aggaatgaaa ctgcttgttg tcggttctgg tggtcgtgag
    15121 catgcgattg ctaaaaagtt acttgaatca aaagacgtgg aaaaagtctt tgtagctcct
    15181 gggaatgatg ggatgactct ggatggtttg gaattggtaa atatctctat ttccgaacat
    15241 tctaaattga ttgacttcgc aaagaccaat gatgttgctt ggacctttat cggtccagat
    15301 gatgcccttg ctgctggtat cgtggatgat tttaaccaag ctgggcttaa ggcctttggt
    15361 ccgactaggg ctgcagcgga gctggagtgg tccaaggatt ttgccaagga aatcatggtc
    15421 aaatatggtg tttcgacagc agcctatggc acattttcag atttcgagga agcaaaggcc
    15481 tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg atggcttggc gcttgggaag
    15541 ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag ccgctcatga gatgcttttg
    15601 gacaataaat ttggtgactc aggtgcgcgc gtggttattg aggaattcct tgaaggagag
    15661 gaattttcac tctttgcctt tgtcaatggt gataagttct acatcatgcc aacggctcag
    15721 gaccacaaac gtgcctacga tggcgacaaa gggcctaaca cgggtggtat gggtgcctat
    15781 gcgccagttc cacacttacc acagagtgta gttgatacag cggttgacac cattgtcaag
    15841 ccagttctag aagggatgat taaagaaggt cgcccttatc tgggagttct ttacgcaggg
    15901 cttatcctga cagctgatgg accgaaagtc attgagttca acgctcggtt cggagatcca
    15961 gaaactcaga ttatattgcc tcgtttgacc tctgactttg ctcaaaatat cacagatatc
    16021 ctggatagca aggagccaaa tatcatgtgg acggacaagg gtgtgactct gggtgtggtt
    16081 gtcgcatcca agggctaccc gctagactat gaaaggggcg ttgagttgcc agccaagaca
    16141 gaaggcgatg tcattaccta ctatgcaggg gctaagtttg cggaaaatag cagagcactg
    16201 ctctcaaacg gcggacgagt ttatatgctg gttaccacag tagccaccgt caaagaagcc
    16261 caagccagca tctaccaaga actatcccaa caaaaaatag aaggactctt ctaccgaaca
    16321 gatatcggaa gcaaggcaat taagtaaaga tataagaata acgcgccgta gtcaccaaac
    16381 acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa tgttctggtc agggggaaac
    16441 ttggagacct taggctcaaa gtttaggaat gaaaccgaag gtttgcttcc gcctccatca
    16501 cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa atacgttaat gatcgtatgg
    16561 tttgcgagcg ttagcgagct aatatagaac aatcaccgcc gttgtgaaag aacgattgga
    16621 tgataatcca atcgttcagg gaaattggaa gaccttgggt ttccaattta ggcatgagac
    16681 acctttggtg gctgctgccg tccctcacaa gctaaggtga ttgttgaaaa agaggaaaaa
    16741 ggagaagaaa tgaaaccagt aatttccatc atcatgggct caaaatccga ctgggcaacc
    16801 atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag cctacgaaaa gaaagttgtt
    16861 tccgcacacc gtacaccaga cctcatgttc aaacatgcag aagaagcccg tagtcgtggc
    16921 atcaagatca tcatcgcagg tgctggtggc gcagcgcatt tgccaggcat ggtagctgcc
    16981 aaaacaactc ttccagtcat tggtgtgcca gtcaagtctc gtgctcttag tggagtggat
    17041 tcactctatt ctatcgttca gatgccgggt ggggtgcctg ttgcgaccat ggctatcggt
    17101 gaagctggag cgactaacgc agctctcttt gccctccgtc tcctctctgt agaagataag
    17161 tccattgcgg atgcacttgc caactttgct gaagaacaag gaaaaatcgc agaggagtcg
    17221 tcaaatgagc tcatctaaaa caatcggaat tatcggtggc ggtcaactgg gtcagatgat
    17281 ggccatttct gctatctaca tgggccacaa ggttatcgcg ctggatcctg cggcggattg
    17341 cccggcctct cgtgtggcgg aaatcattgt ggcaccttat aacgatgtgg acgccctccg
    17401 tcagttggca gaccgttgcg atgtcctcac ttacgagttt gaaaatgtcg acgctgacgg
    17461 tttggatgcc gttatcaagg atggacaact ccctcaaggg acagatctgc tccgcatttc
    17521 gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag gccaaagtca ccgttgcacc
    17581 ttacaaggtt gtgacctcaa gccaagattt ggcagatatc gacttgtcga aaaactatgt
    17641 cctcaagact gcgactggtg gctacgatgg tcatggacaa aaggttattc gttcagaagc
    17701 agacttggaa gcagcctatg cgctagcaga ctcagcagac tgcgtcttgg aagaatttgt
    17761 caactttgac cttgagattt ctgtcatcgt gtcaggaaat ggcaaggagg tgacgttttt
    17821 cccagttcag gaaaatatcc accgcaacaa tatcctgtct aagaccatcg tacaagcccg
    17881 catttctgaa agtctagcag acaaggctaa agctatggca gtgcgaatcg cagaacaact
    17941 caacttgtct ggaactctct gtgtggaaat gtttgcgact gatgatgacg ttattgtcaa
    18001 tgaaatcgcc ccacgaccac ataactctgg ccactactcg atcgaagctt gcgacttctc
    18061 gcagtttgat acccatattc tgggtgttct gggagcgcag ttgccagcta tcaaactcca
    18121 tgcgccagct gtcatgctca atgtcctagg tcaacacgtc gaggctgctg aaaagtatgt
    18181 tgcagaaaat ccaagcgccc acctccacat gtatggtaaa atagaagcaa agcataatcg
    18241 taagatggga catgtgacct tgtttagtga tgtaccggat agtgtggatg agcttgggga
    18301 agggattgat ttttaggaca agtctatgat acaaattatc gttaatacat ttattgaaaa
    18361 ggataagact ggagcagttg ttgaagtgtt gtatgccagt gctgaccaag ataaggtaca
    18421 agctaaatat gaagaactag ctgcacaata ccccgaaaat tatttagcta tctatgatgt
    18481 accgctggat acggatttga atacactaga tcattacccg tctgtgttta ttggaaaaga
    18541 ggagtttgag tagaaatctt ggtttaccta gatagcttat tcccaacagc ttaagaagaa
    18601 aggaaaaatt aacacatgat caaccgttac tctcgccctg agatggcgaa tatttggagt
    18661 gaagaaaata aataccgtgc ttggcttgag gtggaaatcc tctctgacga ggcatgggct
    18721 gagttggggg aaatccctaa ggaagatgtg gctttgattc gcaagaaggc ggactttgac
    18781 atcgaccgta ttttggaaat tgagcaggag acgcgccacg atgtggtggc tttcacgcgt
    18841 gcggtttctg agactcttgg tgaagagcgc aagtgggttc actatgggtt aacttctacc
    18901 gacgtggtgg atactgctta tggttacctc tacaagcagg ccaacgacat catccgtcgt
    18961 gaccttgaaa acttcactaa tatcatcgct gacaaggcca aggagcacaa gttcaccatc
    19021 atgatggggc gtactcatgg tgtgcacgct gagccgacaa cctttggtct taaattggca
    19081 acttggtaca gcgaaatgaa acgcaatatc gagcgcttcg agcatgcggc tgctggtgta
    19141 gaagctggta agatttctgg tgcggttggg aactttgcca atatcccacc atttgtagag
    19201 gagtatgtct gcgataaact tggcatccgt gcccaagaaa tctctacaca agtccttcct
    19261 cgtgaccttc acgctgagta ctttgcggtt cttgccagca ttgcgacttc aatcgaacgt
    19321 atggcgactg agattcgtgg tctacaaaaa tctgagcaac gcgaagtaga agagttcttt
    19381 gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac gcaacccaat cggttctgaa
    19441 aatatgactg gtctggcgcg tgtcattcgt ggtcacatga ttacggctta tgaaaacgtc
    19501 gctctctggc acgaacgcga tatttctcac tcatcagctg agcgtatcat cacaccagat
    19561 acgaccattt tgattgacta catgctcaac cgttttggaa atatcgtcaa gaacttgaca
    19621 gtcttcccag aaaatatgat ccgaaacatg aactcgactt ttggtcttat ctttagccaa
    19681 cgggctatgt tgacattgat tgaaaaaggc atgacccgtg agcaagccta tgacttggtg
    19741 caaccaaaaa cagcctactc ttgggacaac caagtagact ttaaaccact tcttgaggca
    19801 gattcagaag taacatcacg tctcacacaa gaagaaatcg atgaaatctt caacccagtt
    19861 tattacacca aacgagtgga tgatatcttt gaacgtcttg gactaggtga ttaattaaaa
    19921 aataaacagc gagcttcaat ctcgctgttt attttttatc gaaaagactt agtcttcttt
    19981 tcttttagtg agtccatagg ctgctagtgt ggccatgagt cctgcgacta ctagtcctgc
    20041 agaatcgtga gttcctgttt caggaagttt tttctctatt accacaggag ctggatcttg
    20101 aggaagagct ttgctttcct cagcaggagc tggttggctt aggatttcta gttttggttt
    20161 ttcttcagca atagcggctt gtccgttttc atcgcctaca tgtgttacca tagttccgac
    20221 ttcgactatt tgagtaacgg cttcctgtgc tacgacacta tttacaagtg ttttcacttc
    20281 cttaccatcg gcagaagtgc tcacagagta gaagttgcta cgatgtccat tgacgccctt
    20341 agtaatgact tgtgtttttc ctttgagtaa gagtggattt tcacgagtca ctgtggtaaa
    20401 tggaatttct tcttcttgga tatccagtct aggttttacc tcagtagttg gtgcaagacc
    20461 actttcatca cccttgtgag ttacaggagc gccaacttca accacttggt ttataacttc
    20521 tttggttacc tggctatcaa ggactgtttc tgttgttttt ccattttcag tgagtacaga
    20581 gatgtaatga gttcgttcac ctttgactcc tgctgtgata atattttcct gaccagctgg
    20641 gaggttagga ttttctttct tgataacttc aaatggaatt tcttcagttc ttgtgatgag
    20701 ttctggtctg gtttcaacat tggcagccac ttcattttca tctaggcttc ctgaatgagt
    20761 tgcagctggt ttgaggcctt gaagagcggc ttttaggttg gctacaagtg tgtcaagctc
    20821 agcttgttta ttacggttga ggttgtaatt tagagctgtt ttagctgcgt caagggcctc
    20881 aagactttct ttactatatc cttctaagtt tgtaggaatt ttagctaatt cttcgcggag
    20941 agcattataa ttagcacgga agtagtcttt gttgtggtct gcaaaggcag tcatgagttc
    21001 aaagatttcc tcttccttgt attcagcgct tggtctatct gcccagattg aaagcatact
    21061 tccgactgtt ggaagatcta cttcaggata tttggtagaa gctagttgat tgaatggaac
    21121 tttaccagaa ttttcaactg cttttgaaag agggtaagct tcatcttgtt tgtgattgcc
    21181 tataacataa taccagtcac cgttggtatt caagaactta taacccttgc ttgctaggta
    21241 ttgaggtgat gcgaggttgt atccccacca gcctttagac cagtaagaaa tcaagacatc
    21301 tttgtcaaac tgaacatcgt ccttgtcttc atagtagaag ccatcgttga aggccattgg
    21361 ttgaagccct ctttctttgg ccatagctgc gagggtgttg gcatattcgg caaatttgcc
    21421 atagagttga taccacttga ggtagtacca gccttgggca ctagtcgcat cgttggcgta
    21481 ttcgtcagta ccaaagttga aaatctttgt tttacctgca aagaagtcca tgtatttacc
    21541 gatgagggct tttacaaagt tcatcgcttc ttcgtttttc aagtccatag ttgtttttga
    21601 aactttatca aagtgggctt gaggattttt aatacctaat ttttccatgg caaccagcat
    21661 agcatccatg tgacctggac tgttaatagc tgggatgaga ccaatgtcct tagatttagc
    21721 gtattcaatt agctctgtca cttctgcctg tgttagtgca gtaccgtttg gatcgtcgta
    21781 gtaagcttta gttccttcga taatagcttt tttaacgtca tcactagcat aggtttttcc
    21841 gttggcagta atggtcatat cattgagtag aaagcgaagt ccgtcatttc ctagaaggag
    21901 atggacatca gaatatccga gctcactggc cttgtctacg atgcgtttga gctggtccag
    21961 agtaaagtat ttgcgtccag catcgattga gattaccttg tttttggcaa gtttttcaac
    22021 ctcacgttta gcttcttctt ctttttgagc ttcaggcgtg agggtcaagt tgttgacagt
    22081 ttcttgaagt ttagcaatgg ctttatcaat cgtatcttgt tgggcacggc taaggttgct
    22141 atcgagagag cgaatagctt tttcagcttc ttttacggcc gtgacgcttt ctgcagtata
    22201 acggttcagg tcttttggta cctcgttaag tgcttgctct gcagattcat aatcagctgc
    22261 gaagtattca gcgttggcat ttgcaaaatg acgcatgagt ttgaagaggc gtgatggtga
    22321 ataacgtgca gatggagtgt cagcccaagc agctaccata ccaccgatga ttgggatatc
    22381 agctccttct gtttttggta cagaagtgat tggtgtgttt ttaataccat tgagcccctg
    22441 atcgagattg taccagcctt ggccatcagc gtttcgtcca agaacgtagt accaagcatc
    22501 attggtatta aggatttggt gacctttttc agctagtagt ttagaagaag cgacatcgta
    22561 gcctccccaa ccaccagtcc acatagaaac gatgatgtct ttgtcaaaac taccaaagct
    22621 tgtgtcgcta ttgtagtaga taccgtcgtt aaaggccatt ggtttgagac cgtgcgattt
    22681 tacaatacga gcgaggtcat tggcgtaggc aataaatttt tcatagcctt ttacagggta
    22741 gccttcgttt ggatagtatt tatcagcttg aagcacactc caacctttag catctgtcgc
    22801 atcattggca tattcatcaa gtccgatgtt gaagatttca gtctttttcg cgaaataagc
    22861 agcatacttg tcgataaggg cttttgtaaa agcgacagct tgttcgttgt caagatcgac
    22921 agtacgggct gatttcttcc caaaatagct aaagttaggg ttttggattc ccaattcttt
    22981 catggcattg agaatcgcat ccatgtgtcc aggactattt actgtcggaa tgagaccgat
    23041 acctttatct ttggcatagt taatcagatc tgtcatttga ctttctgtta agtgattgcc
    23101 gtttggatcg ttgtaataat catttgtacc tttttcaatg gcgcgtttga catcgtcact
    23161 ggcataggtc ttgccgttag ctgtgatgct catatcgtcc aacatgaaac ggagtccatc
    23221 atttccgact aataggtgta aatcagtgta gccataatgt ttcgctttat cgatgatttc
    23281 cttgagctgt tctggtgaga aatatttacg tccagcatca atagaaacaa ttttcttttt
    23341 cgctagtttt tcatttacag ttgcagcacg ttcctttcct gtctctgttt ccggtttgtc
    23401 agcctctgct ttcgcttcat cttttttagc tggtttatcc ttgtcagtct tgtctgtatt
    23461 tgactcttta gaatcaacct ctttcgcttc ttccttttta gggctagctt cttcttcctt
    23521 tttattagca gtttcttttt cagcagaagt tggagttacc acctctgctt tatcactagg
    23581 agttgaacta acttcctctt gtggtttttc ttctgttttt ggaagactag ctaccttatc
    23641 agtagctgga gtttctgttt ctacagtttt tggagcttct ggttgaagct ctgctttagg
    23701 tgtttcctca gtccgatttt cggatgattg aggggaatca gaaaccgtat ggatggtcgg
    23761 ttggttttct gtagtagtag gagtaactcc atcggctgca acagtctgtg cttggaaggc
    23821 aaatccaatt agaacagaag ctgctcctac agcgtattta cgaatagaaa aacgctgttg
    23881 tttttcatgt ttcattgcaa aacctcctga ttgcattgtt atattgatag cgattatata
    23941 aatcaacgcc tttattttat ttcttatatt aacgagagtc
//
LOCUS       DAVMJI010000031        22757 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.031, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000031 DAVMJI010000000
VERSION     DAVMJI010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.031"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            416..685
                     /gene="blpJ"
                     /locus_tag="VYR58_001532"
     CDS             416..685
                     /gene="blpJ"
                     /locus_tag="VYR58_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV3622663.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            754..1002
                     /gene="blpK"
                     /locus_tag="VYR58_001533"
     CDS             754..1002
                     /gene="blpK"
                     /locus_tag="VYR58_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HEV3622664.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            1246..1395
                     /gene="blpO"
                     /locus_tag="VYR58_001534"
     CDS             1246..1395
                     /gene="blpO"
                     /locus_tag="VYR58_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV3622665.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1499..1618
                     /locus_tag="VYR58_001535"
     CDS             1499..1618
                     /locus_tag="VYR58_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV3622666.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2086..2457
                     /locus_tag="VYR58_001536"
     CDS             2086..2457
                     /locus_tag="VYR58_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622667.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLTSIL
                     VTVYLTREMRLREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            3086..3469
                     /locus_tag="VYR58_001537"
     CDS             3086..3469
                     /locus_tag="VYR58_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV3622668.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            3521..4210
                     /locus_tag="VYR58_001538"
     CDS             3521..4210
                     /locus_tag="VYR58_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3622669.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            4252..4485
                     /locus_tag="VYR58_001539"
     CDS             4252..4485
                     /locus_tag="VYR58_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622670.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            4636..5247
                     /locus_tag="VYR58_001540"
     CDS             4636..5247
                     /locus_tag="VYR58_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3622671.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            5408..6202
                     /locus_tag="VYR58_001541"
     CDS             5408..6202
                     /locus_tag="VYR58_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV3622672.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            6199..6834
                     /gene="trmB"
                     /locus_tag="VYR58_001542"
     CDS             6199..6834
                     /gene="trmB"
                     /locus_tag="VYR58_001542"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV3622673.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6960..7439
                     /gene="rimP"
                     /locus_tag="VYR58_001543"
     CDS             6960..7439
                     /gene="rimP"
                     /locus_tag="VYR58_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV3622674.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            7483..8619
                     /gene="nusA"
                     /locus_tag="VYR58_001544"
     CDS             7483..8619
                     /gene="nusA"
                     /locus_tag="VYR58_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV3622675.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8641..8934
                     /locus_tag="VYR58_001545"
     CDS             8641..8934
                     /locus_tag="VYR58_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV3622676.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8927..9226
                     /locus_tag="VYR58_001546"
     CDS             8927..9226
                     /locus_tag="VYR58_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV3622677.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            9243..12035
                     /gene="infB"
                     /locus_tag="VYR58_001547"
     CDS             9243..12035
                     /gene="infB"
                     /locus_tag="VYR58_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV3622678.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            12286..12636
                     /gene="rbfA"
                     /locus_tag="VYR58_001548"
     CDS             12286..12636
                     /gene="rbfA"
                     /locus_tag="VYR58_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV3622679.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            12915..13694
                     /locus_tag="VYR58_001549"
     CDS             12915..13694
                     /locus_tag="VYR58_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622680.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLCAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIIAGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            13696..13878
                     /locus_tag="VYR58_001550"
     CDS             13696..13878
                     /locus_tag="VYR58_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622681.1"
                     /translation="MNPIKAFDKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIRPEERE"
     gene            13838..14026
                     /locus_tag="VYR58_001551"
     CDS             13838..14026
                     /locus_tag="VYR58_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622682.1"
                     /translation="MRLGGSLGQRRENEIFFGLLAILFIKPIIGIVKFFWMIISFAVQ
                     LLFYKILFKILDWLFKLI"
     gene            complement(14321..14398)
                     /locus_tag="VYR58_001552"
                     /pseudo
     CDS             complement(14321..14398)
                     /locus_tag="VYR58_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14429..14662
                     /locus_tag="VYR58_001553"
     CDS             14429..14662
                     /locus_tag="VYR58_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV3622683.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            14662..15996
                     /locus_tag="VYR58_001554"
     CDS             14662..15996
                     /locus_tag="VYR58_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV3622684.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTIAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            16006..16260
                     /locus_tag="VYR58_001555"
     CDS             16006..16260
                     /locus_tag="VYR58_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV3622685.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            16356..16751
                     /locus_tag="VYR58_001556"
     CDS             16356..16751
                     /locus_tag="VYR58_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV3622686.1"
                     /translation="MSKKLNRKKQLRNGLRRSGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            17163..17612
                     /locus_tag="VYR58_001557"
     CDS             17163..17612
                     /locus_tag="VYR58_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEV3622687.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            17599..18156
                     /locus_tag="VYR58_001558"
     CDS             17599..18156
                     /locus_tag="VYR58_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622688.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKVTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            18158..19120
                     /locus_tag="VYR58_001559"
     CDS             18158..19120
                     /locus_tag="VYR58_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV3622689.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDINFTYRF
                     CHSLRNYSEHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            19132..21783
                     /locus_tag="VYR58_001560"
     CDS             19132..21783
                     /locus_tag="VYR58_001560"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV3622690.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAINPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPELGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTINPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            21853..22608
                     /locus_tag="VYR58_001561"
     CDS             21853..22608
                     /locus_tag="VYR58_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV3622691.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
BASE COUNT         6967 a         3995 c         5062 g         6733 t
ORIGIN      
        1 tttacttact tacaaaatat caaagttatc taagaatcat gagaataaga tagttagcaa
       61 aattttaatt atattatcaa tcgtttatgt aatcgttgat gctttactta gttgatggat
      121 tggtaggaat aaaaaactta actataaact attatttact aatatttttt gctttctgca
      181 agttaataaa tagtatagta aaacttttta ttgcaaggag aataacgaaa ttaagatatt
      241 ttagatactc aagattattg aaatcttaga ctaaaaaata ggtactgcta cctttaagaa
      301 gatagtagac gtatatactt ttttaagaaa atcaaaaaga tactaaaaaa aatctatttg
      361 tttattgaat ttaagacttt ggtaacaaat tgaaaataaa aaggaggtat tcatcatgaa
      421 tacaaaaatg ttgtcacagt tagaggttat ggatactgaa atgcttgcga aagttgaagg
      481 ggggtatagc tccactgatt gtcaaaatgc actgattaca ggagtcacta cgggaattat
      541 aactggtgga actggagcag gtttggccac tttaggagta gctggacttg ctggtgcatt
      601 tgttggagca cacattggtg caattggggg tggattaaca tgcttaggag gtatggttgg
      661 tgataaattg ggactaagtt ggtaagactt atagtaaaat tatgaggatt ctattctgat
      721 ttattttagt tttttaaaaa aggagtattt gtcatggata caaaaatgat gtcacaattt
      781 tctgttatgg atactgaaat gcttgcttgc gttgaaggtg gcggatgcaa ttggggagat
      841 tttgccaaag caggtgttgg aggagcagct gtagttgctg ctttaggttg tgcagcgggt
      901 ggagtgaaat atgggaaaat tctaggacca tggggcgctg caataggagg aattggagga
      961 gcagtggttt gtggatattt agcctatacc gctacatcat aaaaatgaaa gctaaatttt
     1021 atgaaggcta tattctttat tattctcttc gcttttcaaa cctatcttat ttatctatcc
     1081 ataagtatct ctgataaaaa acaaaagact attgaattaa catcattgaa ttgttttgtc
     1141 atattatttc taatctatga taaattaatt tttctcttta ttgcctatgt ttttttgata
     1201 atttttatat taaacttgtt ccgtaactga aaagtgacat actatatgaa tacaaaaatg
     1261 atgtcacaat tttctgttat ggataatgaa atgcttgctt gcgttgaagg tggagatatt
     1321 gattggggaa gaaaaattag ttgtgcagca ggggttgcat atggcgcaat tgatgggtgt
     1381 gcaacaacgg tttgacattt ctattgggac catttgctat aggaataggt gtaactggtg
     1441 ctgcaggtgg agctatactt ggaggtgtag cctatgcagc aacatgttgg tggtaattat
     1501 ggattttaaa agttttatta ttggtttagt agttggtata tttggtcctt atatggatga
     1561 cttaattaga aaaatatttt caaaatcttc caaaaaggat acggatagta ctctctaaaa
     1621 aataaatttc tcccctgtat ttgctagctt aatttacagg ggagtttctt taatattgtt
     1681 tcgcctgtca aaatgatatg tgatagcagg atgaaaagtc tacaaacaag ttggtatcaa
     1741 tacaatataa agaggaaagt atgtttttca tgcttgcttt tttaattttt acaattcaag
     1801 aggttttgat gaccatttat gatttgagtg atccaaggtc aaaataagtg ctatactagc
     1861 agtgtaaatg ttcttgctca actaagataa atcgcacatt taggaggaaa acttatgaag
     1921 aaaaaaatac tgattatttt cgttctgtat ctgatcatgt ccatctttct ttatccgctt
     1981 agggagagta tttggtataa tctattttat accatagcct atatgattgc ggttatgatc
     2041 tatttttctt taattaaaaa gaaagaaaag aaatgaaaga ttttcttgat taaaaagaat
     2101 catattcttt gtgagattgt tcctgggtca gttgcctttg cttgtttcta cttatctatt
     2161 tctatttcgt cagttttcca atttctttta gtagttatta acttgacttc tattttggtt
     2221 actgtttatc ttactaggga aatgagatta agagagtttg aagatgatga tttggttagt
     2281 cctagaacca atcaactcat gtttatcggc ttgacaggct ttatgtctat tatttgtttg
     2341 tatagaggta tcacagcagg agaatcttat caacaactaa tcgcttatat tggtgctatt
     2401 ctttgcttga tcatcatgct tctactcatt tggggtttga agtattataa aaagtagggg
     2461 ctaatgaagt ttttgcaatt taggaggttt cgatgacaat tcaagatttg gatgaaaaat
     2521 tttaaaaaac aatgatatac taaacttgtc aaagttgcaa cgggtgctgc tacattatgt
     2581 taaaaatcgc tcttgattga taagttggat ttgttaggaa aggagtaaat aattatggat
     2641 aagaaaaaga tagtttcgac tataatatgt atagtatttc ttgtagtgtc agtagataat
     2701 ttttttagag acttaacccc gttactgttc attttaaata ttattggcct gtcttgcttt
     2761 tcagtgctaa catacattaa cataaaagag atactcttaa atataagtaa atgatgattt
     2821 ggttagtcct agaaccaatc aacttatgtt tatcggcttg gcagatttta tgtttgtcat
     2881 ttgtttgtat agaggtattt cagaaacaga attctatcaa caactaatcg cttatatagg
     2941 tgtattctct gcttgtttat cacgcttctg ctcatgtggg gcttgaagta ttataaaaag
     3001 tagctttcta tccttttctg acaggatatt tgagtagaag gctctattaa attgttagtg
     3061 aaataaatga atggaggtat ttaatatgaa atacagatta ttttttgtta ttttcttgag
     3121 tagtgtgttg gatattcttt tagggacatt tttacaaatc tctatcgtat ctattgggtg
     3181 gcttgttctt tacagtggtt tgtttgaagc aggagttttc cttcttgcta ataaaggggt
     3241 ggcggtaaaa atcaaggaag tagatattcg aaatcgcttt aaatttattt ttggaaaaac
     3301 cttatggttt caaattcttt tgctcatctt tttgataatc aaactttatc ttggtttgga
     3361 tgcgaggttg attttattct atggacatat tttcattgtc tttaatgcct taatgtatct
     3421 attatctagt agtcaggtta gccttaaaaa aaacaaactg tcttcttaat cttacagcag
     3481 tagagcctga caaggtgagg tcatagtagg gaggatttct atgaaaaagt atcaacttct
     3541 attcaaaata agtgcagttt tctcttactt atttttcgta tttggtcttt ctcagatgac
     3601 gcttattatt caaaattatt ggcaattttc ttcccagatt ggcaatttcg tctggattca
     3661 aaatttcttg agtttgctat ttagcggagt catgatttgg attctggtta agacaggtca
     3721 tggttatctc tttcacattc caagaaaaaa atggctttgg tattcgattt tgacagtatt
     3781 agtggtagtg ctccagatct cttttaacgt tcagacagct aaacatgttc agtcaactgc
     3841 tgaaggttgg gctgtattga tcggttatag tgggaccaac tttgctgagc taggtatcta
     3901 tataactttg ttctttctga ctccacttat ggaagagcta atctatagag gattactgca
     3961 acacgccttt tttaagcatt cgagatttgg ccttgatttg cttcttccgt caattttatt
     4021 tgctcttcct catttttcaa gcctgcctag tttgttagat atcttcatct ttgcaacatc
     4081 tggcatcatc tttgctagtt tgacccgcta taccaagagc atttatcctt cctatgcggt
     4141 gcatgtgatc aataatattt tcgcaacatt accatttttg ctgacttttt tacatagggt
     4201 cttggggtaa aaaaacaaaa ggcttgcttt tcagccatag aggagattat catgtataaa
     4261 cacttatttt tcctagattc caaaacttta gatcggttga caccctatat tctagtcttg
     4321 gcttctgaca ccattgcttt taatgttttt gtgctaacct ttgtatctgc ggtggttttt
     4381 aatttcctaa attccatgct agctttaatg gctatattca taggggctgg ctatgtggtc
     4441 ggattttggt tactaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
     4501 ctgtacttga gtacggcaag gcgacgttga cgtggtttga atttgatttt cgaagagtat
     4561 aaaatggttt gttttggaaa ggctagaact aaagaatgac gcgtaggaag tctgtttggt
     4621 gaggaggata gttttatgga gttttttgat aaatttcatg ccttgtgttt tggattttta
     4681 gtactaataa ttgtcattac agttccttat acgattaacc atgggggttt ttttcaaaat
     4741 gaatctgcat tgattcttgt aagtcttctt gtaacctcgc tgagtgttgc ttatgctaga
     4801 aagtttgaaa tgatttcttt tgggatgtta agcaagaaac aacttttgct tttcattgca
     4861 atctttcttc taagtgtact tgagacgctg gtttatattc atttcttcgc tgtttcttct
     4921 ggctcagggg tccaacactt ggcggaagtc agcagaggaa tttccctgtc tttgattttg
     4981 actacctcag tttttggccc catccaggag gaactcattt tcagaggact tcttcaaggt
     5041 gcggtttttg acaattcttg gttagggctt gtgctaactt cctctctctt ttctttcatg
     5101 catggacctt ctaatgtccc ttcgtttatt ttttatctac ttgggggttt gttgctgggc
     5161 tttgcttata aaaagagtca aaacctatgg gtttctactc tagtccacat gttttacaac
     5221 agttggccac tcctatatta tttataaaaa ttatgaaaag gtaagcagaa gatggtgctt
     5281 acctttttca agctataatg atacccaagc caatccagag gcttttcttt gagaatcggg
     5341 ttagagtggt tgacgaatag gccaaaaact agtagaatag taaggaaact ttatacggag
     5401 gaaagaaatg gatttgggtg ataatgagct aacactgact cccatacctg ggaaaagtgg
     5461 caaggcttat atgggtagct atcctgacgg gaagcgcatc tttgtaaaaa tgaacacctc
     5521 tccaatccta cctggtctag ctagagaaca aattgctcca caattattat ggagtcgtcg
     5581 tttggcagat gggcgtgata tgtgtgctca agaatggttg acaggcaaga tattgacccc
     5641 ctatgatatg aatcgtaagc aaatcgtcaa tattttaacc cgtcttcatc gctcacgtcc
     5701 gttgatgaca caattgagtc gtttgggcta tgccatggaa acacctgtag atttactaca
     5761 gtcttggcag gaaacggctc cagatgcttt gcgtaaaaat cattttatca gtgaagtgat
     5821 ggctgattta cgtcagacta ttccaggatt tagagaggac catgcgacca ttgtccatgg
     5881 agatgtacga catagtaatt ggattgagac agatagtggc ttgatttatt tagtagattg
     5941 ggattcggtt cgcttgaccg atcgcatgtt tgatgtggcc catatgctct gccattatat
     6001 ttcagaacat cagtggaagg aatggttgac ctactacggt tacaagtaca atcaaacggt
     6061 attaagtaaa ttgtattggt atggtcaatt gtcttatttg agtcagattt ccaagtatta
     6121 tatgaaccaa gatttagaaa atgtcaatcg ggagattcat ggtttgcgtc atttccgaga
     6181 caagtatgga aagagaagat gagagttaga aatcgtaaag gggcaacaga attactagag
     6241 gcaaatcccc agtatgtggt cctcaatccc ttggaagcca aggcaaaatg gcgggacttg
     6301 tttggcaatg ataatcccat tcatgtggaa gttggaagtg gaaagggtgc ctttgtttca
     6361 ggtatggcca agcaaaaccc tgacatcaac tatatcggga ttgatattca aaagtctgtt
     6421 ttgagctacg ctttggacaa ggtgcttgaa gttggagtgc ctaacatcaa gctcttgtgg
     6481 gtagatggtt ctgacttaac tgactatttt gaagacggtg agattgatcg cttgtatctg
     6541 aacttttcag atccatggcc gaaaaaacgc catgaaaagc gtcgtttgac ctacaagacc
     6601 ttcttggata ccttcaaacg tatcttgcct gaaaatggag aaattcattt caagacggat
     6661 aaccgtggct tgtttgagta cagtttagtg agcttttctc aatatggcat gaaactcaat
     6721 ggtgtctggt tagatttgca tgccagtgat tttgaaggta atgtcatgac agaatacgag
     6781 caaaaattct caaacaaggg gcaagttatc taccgagttg aggcagaatt ttaagagata
     6841 gcctaaaatt aggctgtaca agtgcttttg ctttacataa gttggcaaac gtgctatact
     6901 gatagtaaga atatgaaaag tgaggcgggg aaatatcttc gcctcttgct tatgaggagg
     6961 tggacgcaat cgcaacaatc gtagaattag tcagagaagt tgtagaacct gtcatagaag
     7021 ctccttttga actcgtggat atcgagtatg gaaagattgg cagtgacatg attctcagta
     7081 tttttgtaga taaacccgaa ggaattacct tgaacgacac ggcagacttg acagaaatta
     7141 tcagtcctgt cctagacacc atcaagccag atcccttccc agaacaatat ttcctagaaa
     7201 ttaccagtcc aggtttggaa cgccctttga aaaccaagga tgccgtcgct ggagcggttg
     7261 gaaaatacat ccatgtcggg ctctaccaag ccatcgataa gcaaaaggtc tttgaaggaa
     7321 ccttgttggc cttcgaagag gacgagttga ctatggaata tatggacaag acgcgtaaga
     7381 aaaccgtcca aattccatac agtttagtat caaaagcacg tttagcagtt aaattataga
     7441 aaaagaaagg atagcttttg aggattcaaa agtgaagaaa acatgagtaa agaaatgcta
     7501 gaggccttcc gcattttgga agaagacaag ggaatcaaaa aagaagatat catcgacgca
     7561 gtagtagagt cgcttcgttc cgcttatcgc agacgctatg gtcagtcaga cagcgtagct
     7621 attgacttca acgaaaaaac aggtgacttt acagtttata ctgtccgtga agttgttgat
     7681 gaagtatttg atagccgttt ggaaatcagc ttgaaagatg ctcttgccat taattcagct
     7741 tatgaacttg gagacaaaat caagtttgaa gaagcaccag ctgagtttgg tcgtgtagca
     7801 gcccagtctg ccaaacaaac catcatggaa aaaatgcgca agcaaacacg tgccatcact
     7861 tacaatactt acaaagaaca tgagcaagaa atcatgtctg gtacagtaga acgctttgac
     7921 aaccgcttta tctatgtcaa ccttggtagc atcgaagccc aattgtcaaa acaagaccaa
     7981 attcctggag aagtttttgc ttctcatgat cgtatcgaag tttatgttta caaggttgaa
     8041 gacaaccctc gtggtgtgaa tgtctttgtt agccgtagtc atccagaaat gatcaaacgt
     8101 ttaatggagc aagaaattcc agaagtttat gatggaactg ttgaaatcat gagcgtggct
     8161 cgtgaagcag gtgaccgtac gaaggttgct gttcgtagcc acaatccaaa cgtggatgct
     8221 atcggtacaa tcgttggacg tggtggtgct aatatcaaga agattactag caaattccac
     8281 ccagctcgtt acgatgctaa aaatgaccgc atggtaccaa tcgaagaaaa tatcgatgtt
     8341 atcgagtggg tagcagatcc agctgaattt atctacaatg ccatcgctcc tgctgaggtt
     8401 gaccaagtta tctttgatga aaacgacagc aaacgtgcct tggtggttgt tccagataac
     8461 aagctttctc ttgccattgg tcgtcgtgga caaaacgtgc gcttggcggc tcacttgact
     8521 ggttaccgta tcgatatcaa gtctgctagc gaatttgaag ccatggaaga cgctgcttca
     8581 gtagagttgg aagtagaaaa cgatactgta gaagaataaa agctgctaga ggagggaaag
     8641 atgaaaacaa gaaaaatccc tttgcgcaag tctgttgtgt ctaacgaagt gattgataag
     8701 cgtgatttgc tccgcattgt caagaacaag gaaggacaag tctttattga tcctacgggc
     8761 aaggccaatg gccgcggcgc ttatatcaaa ctagacaatg cagaagccct agaggcgaaa
     8821 aagaagaagg tctttaaccg cagctttagc atggaagtgg aagaaagctt ttatgacgag
     8881 ttgatcgctt atgtggatca caaagtgaaa agaagagagt tgggacttga ataagcaaaa
     8941 gataagtaat ctcttggggc ttgctcagcg agcagggcgc atcatatcgg gtgaagaatt
     9001 ggtggtcaag gccattcaag acggcaaggc caagttggtc tttctagctc atgatgctgg
     9061 acccaatctg accaagaaga ttcaagataa aagtcattat tatcaagtag aaattgtaac
     9121 cgtgttttca acactggaat taagcatagc agtcgggaaa tcgagaaagg ttttggctgt
     9181 aacagatgct ggatttacaa agaaaatgag gtctcttatg gaatagaaga ggaggacatg
     9241 atttgtctaa gaaaagattg tacgaaatcg caaaagaact tggaaaagaa agtaaagaag
     9301 ttgtagcgcg tgcaaaagag ttgggcttgg atgtgaaaag ccactcatca agtgtggaag
     9361 aagctgtcgc tgcaaaaatt gctgccagct ttaagcctgc agctgctccg aaagtagaag
     9421 caaaacctgc agcaccaaaa gtaagtgcag aaaagaaagc cgaaaaatct gagccagcta
     9481 aaccagctgt agctaaggaa gaggcaaaac cggctgagcc agttgctccg aaaacagaaa
     9541 aagtagcagt gaaaccgcaa agtcgtaatt tcaaggctga gcgtgaagcc cgtgctaaag
     9601 agcaggcaga acgacgcaag caaaataagg gcaataaccg tgaccaacaa caaaacggaa
     9661 accgtcagaa aaacgacggc cgtaatggtg gaaaacaagg tcaaagcaac cgcgacaatc
     9721 gtcgctttaa tgaccaagct aagaagcagc aaggtcagca aaaacgtaga aatgagcgcc
     9781 gtcagcaaga ggataaacgt tcaaatcaag cggctccacg tattgacttt aaagcccgtg
     9841 cagcagccct aaaagcagag caaaatgcag agtacgctcg ttcaagtgag gaacgcttca
     9901 agcagtatca ggctgctaaa gaagccttgg ctcaagctaa caaacgcaag gaaccagagg
     9961 aaatctttga agaagcggct aagttagctg aacaagcaca gcaagttcaa gcagtggttg
    10021 aagtcgtccc tgagaaaaaa gaacctgcag tggatacacg tcgtaaaaaa caagctcgac
    10081 cagacaaaaa tcgtgacgat tatgatcatg aagaagatgg tcctagaaaa caacaaaaga
    10141 atcgaagtag tcaaaatcaa gtgagaaatc aaaagaatag taactggaat aacaacaaaa
    10201 agaacaaaaa aggcaataac aagaacaacc gtaatcagac tccaaaacct gttacggagc
    10261 gtaaattcca tgaattgcca acagaatttg aatatacaga tggtatgacc gttgcggaaa
    10321 tcgcaaaacg tatcaaacgt gaaccagctg aaattgttaa gaaacttttc atgatgggtg
    10381 tcatggccac acaaaaccaa tccttggatg gggaaacaat tgaactcctc atggtggatt
    10441 acggtatcga agccaaacaa aaggttgaag tggataatgc tgacatcgaa cgtttctttg
    10501 tcgaagatgg ttatctcaat gaagatgaat tggttgagcg tccaccagtt gttactatca
    10561 tgggacacgt tgaccacggt aaaacaaccc ttttggatac tcttcgtaac tcacgtgttg
    10621 cgacaggtga agcaggtggt attactcagc atatcggtgc ctaccaaatc gtggaaaatg
    10681 gtaagaagat taccttcctt gatacaccag gacacgcggc ctttacatca atgcgtgcgc
    10741 gtggtgcttc tgttaccgat attacgatct tggtcgtagc ggcagatgac ggggttatgc
    10801 ctcagactat tgaagccatc aaccactcaa aagcagctaa cgttccaatc atcgtagcca
    10861 ttaacaagat tgataaacca ggtgctaacc cagaacgcgt tatcggtgaa ttggcagagc
    10921 atggtgtgat gtcaaccgct tggggtggag attctgaatt tgttgaaatc tcagctaaat
    10981 tcaaccaaaa tatcgaagaa ttgttggaaa cagtccttct tgtagctgaa atccaagaac
    11041 tcaaggcaga cccaacagtg cgtgcaatcg gtacggttat cgaagcgcgc ttggataaag
    11101 gaaaaggtgc ggtcgcaacc cttcttgtac aacaaggtac cttgaatgtt caagatccaa
    11161 tcgttgtcgg aaataccttc ggtcgtgtcc gtgctatgac caacgacctt ggtcgtcgtg
    11221 ttaaagttgc tggaccatca acaccagtct ctatcacagg tttgaacgaa gcaccgatgg
    11281 cgggtgacca ctttgccgtt tacgaggatg aaaaatctgc gcgtgcagca ggtgaagagc
    11341 gtgccaaacg tgccctcatg aaacaacgtc aagctaccca acgtgttagc cttgaaaacc
    11401 tctttgatac ccttaaagct ggggaactca aatctgttaa tgttatcatc aaggctgatg
    11461 tacaaggttc tgttgaagcc ctttctgcct cacttcaaaa gattgacgtg gaaggtgtca
    11521 aagtgactat cgtccactca gcggtcggtg ctatcaacga atcagacgtg acccttgccg
    11581 aagcttcaaa tgcctttatc gttggtttca acgtacgccc tacaccacaa gctcgtcaac
    11641 aagcagaagc tgacgatgtg gaaatccgtc ttcacagcat tatctacaag gttatcgaag
    11701 agatggaaga agctatgaaa gggatgcttg atccagaatt tgaagaaaaa gttattggtg
    11761 aagcggttat ccgtgaaacc ttcaaggtgt ctaaagtggg aactatcggt ggatttatgg
    11821 ttatcaacgg taaggttgcc cgtgactcta aagtccgtgt tatccgtgat ggtgtcgtta
    11881 tctatgatgg cgaactcgca agcttgaaac actacaaaga cgacgtgaaa gaagtgacaa
    11941 acggtcgtga aggtggattg atgatcgacg gctacaatga tattaagatg gatgatgtga
    12001 ttgaggcgta tgtcatggaa gaaatcaaga gataagattt tttgctcctt tcttaggtgg
    12061 tgagggacgc aagcaaaccg atggtttcat tgcttatttt tgagcctagg gtctcaaaaa
    12121 tcccctgtga tgggactgat aaatcagttc catcactttc accacggcga aagaagcaga
    12181 tgacttcaaa ttgaacttcg tttcaattta aactgaaaat caagaagttt aaaatagcta
    12241 ggtctgctgg cctagctttt ggttcaaagt agagaaagga atatcatggc aaatcatttc
    12301 cgtacagatc gtgtgggcat ggaaatcaag cgtgaagtca atgagatttt gcaaaagaaa
    12361 gtccgtgatc cacgtgtcca aggtgtgacc atcacagatg ttcagatgct gggtgacttg
    12421 tctgttgcca aggtttatta caccattttg agtaaccttg cttcggataa ccaaaaagcc
    12481 caaatcgggc ttgaaaaagc aactggtacc atcaaacgtg aacttggtcg caatttgaaa
    12541 ttgtacaaaa tcccagattt gaccttcgtc aaagacgagt ccatcgagta tggaaacaag
    12601 attgacgaga tgctacgcaa tctggataag aactaaagaa gaggggttgc ccctcttttt
    12661 tggtggagga aaataggttg aatttgaaat ggaaaaatat tcttttaaaa tatattgaaa
    12721 ctagaatagt acgcctctac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc
    12781 gatttgtcct gttcttgttt cattttacta taaaaaaggg gttctgtatt ttttaatgtt
    12841 atctaattag aaaatgcttt ttttgtagga aatataatat gataaggtgt aaaaaagaaa
    12901 taaggagttt gtatatggct gaacaagact tagctatgca agtattgcaa caagtggtga
    12961 aactacctgt tgttaaggtt gatcgttcga aatttttagt ggataagttt tccaaagaat
    13021 tggatccaaa agatattcct accttattgg aacaaggtac aacgactctt ctatctcaag
    13081 aaatattaga tcgtgtagct aatgcttgta ttcgggacaa tgtattatta gcgagtggga
    13141 cttctgtttt ggcaggatta gctggagggc ttgctatggc aattaccatt ccagctgatg
    13201 tggctcaatt ttatgctttc tctctgaaat tggctcaaga attaggttat atttatggtt
    13261 atgaggatct ttgggcttca cgcgaggagt tgagtgaaga tgctcaaaat accctcttgc
    13321 tttatctagg cgtaatgtta ggggtgaatg gaaccgctgc tttgctatgt gctggtggta
    13381 taacaattgc caaacaggta atgaaaacag tgcctaataa agctttaaca aagacgcttt
    13441 ggtaccctat tttgaaaaaa gtcttaaaaa tatttggtgt gaatcttacc aagggagggc
    13501 tggccaaagg aatagggaaa tttattccta tcttgggtgg tatcattgca ggtggtttaa
    13561 cctttgcaac tatgaaacca atgggggaaa gcttgcagaa agaattatcc aagctagtca
    13621 actatagtga agttcaatat caagaagatg ttgaaacaat ccgaaaagag gctgaaatca
    13681 ttaaaggaga gtaatatgaa tcctatcaaa gcttttgata aaatttatgg taattacttt
    13741 ttgaccgtgc aaggtgtaaa agtgatgaaa acgataaaga aagctgacca tgtcgttgtt
    13801 ggtctgggaa aactttttat tgcagataag ctaatggata cggctcggtg gctcattagg
    13861 ccagaggaga gagaatgaaa ttttttttgg tcttcttgct attcttttta tcaaaccgat
    13921 tattgggatt gtgaaattct tttggatgat catttccttt gcagttcaat tgctgtttta
    13981 caagatatta tttaagatat tggattggct ctttaaactt atctagatgg taatccaagt
    14041 cgcagagagc tagcaggaac tccactgcta gttttttaat ctctctccat atggtataat
    14101 ataagcagta aaatcatttt atactcttcg aaaatctctt caaaccacgt cagcttcacc
    14161 ttgcagtata tatgttactg acttcgtcag ttctatccac aacctcaaaa cggtgttttg
    14221 agctgacttc gtcagttcta tccacaacct caaaacggtg ttttgagctg acttcgtcag
    14281 ttctatccac aacctcaaaa cggtgttttg agctgacttc gtcagttcta tctacaacct
    14341 caaaacactg ttttgagcaa cctgcggcta gctttctagt ttgctctttg attttcattg
    14401 agtattagaa catataatgg aggtcgtcat ggacaatatc atcgatgtgt caattcctgt
    14461 tgcagaagtg gtggacaagc atccagaagt cttggaaatt ctagtggagc tgggttttaa
    14521 accccttgcc aatcccttga tgcgcaatac agttggtcgt aaagtatcac ttaaacaagg
    14581 ttctaagcta gcaggaactc ctatggacaa gattgtacgc acactggaag cgaatggcta
    14641 cgaagtgatt ggattagact aatggcagat gaacggattc atgtcctacg ggatatttta
    14701 ttagaattgc ataatggcgc ctctcctgag tcggttcagg agcgttttga tgcgaccttt
    14761 gcgggtgtct cagccattga gatttccctt atggagcacg agctgatgaa ctcagactca
    14821 ggtgtcacct ttgaagatgt tatggaactc tgtgatgtcc atgccaatct ttttaaaaat
    14881 gctatcaaag gtgtcgaagt ttcagatact gagcatccag gtcacccagt tcgtgtcttc
    14941 aaagaagaaa atctggctct ccgtgcggcc ttgattcgca ttcgtagatt gttagatacc
    15001 tatgagtcta tggaagacga ggaaatgctg gcggagatgc gtaagggttt ggtgcgtcag
    15061 atgggacttg tgggtcaatt tgatatccat taccaacgta aggaagaact cttctttcct
    15121 atcatggagc gctatggaca cgattcacct cccaaagtta tgtggggagt ggatgatcag
    15181 attagggaac tctttcaaac agctctaacg atagccaagt cactaccaga agtgtcaatt
    15241 agcagtgtaa aggaagcttt tgaagctttt gcgacagagt ttgaaagtat gattttcaag
    15301 gaagagtcca tcctcctcat gattctcctt gagtctttta ctcaggatga ctggcttcag
    15361 attgcggagg agagcgatgc ctatggctat gccatcatcc gtccgtcaga gaaatgggtg
    15421 ccagaacgac agagctttat tgaggaaaag attgcagagg agcctgtaca gctagatacg
    15481 gcagaaggtc aagttcaaca agtcatagat acgccagaag gccattttac cattaccttt
    15541 acccctaagg aaaaggaagc tgtgctggac cgccatagtc aacaggcttt tggtaatggc
    15601 tatctttcag tcgagcaggc caatctcatc ctcaatcacc tccctatgga gattaccttt
    15661 gtcaataaag atgatatttt ccagtattac aatgacaata cgccagctga tgagatgatt
    15721 ttcaaacgga cgccgtctca agtcgggcgc aatgtcgaac tctgccatcc gcctaagtac
    15781 ttggacaagg tcaaaactat catgaagggg cttcgtgagg ggaccaagga caagtatgaa
    15841 atgtggttca agtctgagtc gcgaggtaag tttgtccaca tcacctatgc tgcagtacac
    15901 gatgaagacg gagaattcca aggagtgttg gagtatgttc aggatatcca gccctaccgt
    15961 gagattgata cggactattt tcgtggatta gaataaggag aaaaaatgag ttacgaacaa
    16021 gaatttatga aggaatttga agcttgggtc aatacccaaa tcatgattaa cgacatggcg
    16081 cacaaggaaa gtcaaaaagt ttacgaagaa gaccaggacg agcgtgccaa agatgccatg
    16141 attcgctacg agagtcgctt ggatgcttat cagttcttgc ttggtaagtt tgaaaacttc
    16201 aaagcaggca agggattcca tgatttgcca gaaggcttgt ttggtgagcg aaattattaa
    16261 acgagaaaga ttcttgattt ttcactaaaa tcttgataga atgtttatgt taaatccttg
    16321 tcagagcagg gattttttat tgaaaggatt ttatcatgtc aaagaaactc aatcgtaaaa
    16381 aacaattacg aaatggcctc cgtcgctcag gtgccttttc aagtactgtg actaaggttg
    16441 tagatgagac aaaaaaagtc gtgaagcgtg cagaacagtc agcaagcgca gctggtaagg
    16501 ctgtttctaa aaaagttgaa caagcagtag aagctaccaa agagcaagct caaaaagtag
    16561 ctaattctgt agaagatttt gcagcaaact tgggtggact tccacttgat cgtgccaaga
    16621 ctttctatga tgaaggaatc aagtctgctt cagatttcaa aaactggact gaaaaagaac
    16681 tccttgcctt gaaaggaatc ggcccagcta ccatcaagaa attgaaagaa aatggcatca
    16741 agttcaagta atttttcttg agccttgcat ttccgagaaa aacttgctac aatagagcca
    16801 ttagaggtgt tttgaatccc acattttaca gaaagtggcg gcgctgagaa gtccacaaat
    16861 gtgtcaaaac tggttgctaa tgactgaaaa aatgaaatat ttctgtcttt ttattttaaa
    16921 gactaaagat gcgggcttgg cccgaaattg ggtggtaccg cggataaaca cattcgtccc
    16981 tgtcatgtag atggcagggc ttttcttttg tgtcttagtc aaaggaggtt gttataaaac
    17041 aatcatttaa aactaataaa ctatattatg gttttcctgt ttttatttta ggatatcaag
    17101 attagaattt tggctataac atcacgacct gtagttcctc ttatagtcta ggagattggg
    17161 ttgtgattgg agtcgttgcg agagagaatg ccgcagagca gatcaaacag tatcaaaaat
    17221 ttactgtgaa tatttctgat gaaacttcta tgcttgcgat ggagcaggct ggttttatca
    17281 gtcatcagga gaaattggaa cgtttgggag tgcattatga aatttctgaa cgaactcaga
    17341 ttcctatttt agacgcctgt ccacttgttt tagattgtcg ggtagatagg attgttgagg
    17401 aagacggtat ttgccacatc tttgccaaga ttcttgagcg acttgttgcc ccagaactcc
    17461 tggatgaaaa gggacatttt aaaaatcaac tgtttgcccc aacctatttc atgggagatg
    17521 gatatcagcg cgtttatcgc tatctggata agcgtgtaga tatgaagggc agtttcatca
    17581 aaaaagcgag gaagaaggat ggcaagaact gagctgccag ataaaatcga aacagaacgt
    17641 ctcgttttac gagtccgtac tgtggcggat gctgaggata tctttgacta tgctagtttg
    17701 ccagaggtcg cctatccagc aggttttcct ccagtcaaga ccttggaaga tgagatttat
    17761 tatctggagc acattcttcc ggagcgtaat caaaaggaaa atctcccagc aggctacggg
    17821 attgtcgtca aagtaacgga taagatcgtt ggctctgtcg atttcaacca tcgccatgaa
    17881 gatgatgtgc tggaaatcgg ctatacctta cacccagact attgggggcg aggttatgtg
    17941 ccagaagctg cgcgtgcctt gattgactta gcctttaaag atttgggtct tcacaagatt
    18001 gaactaactt gctttggata taaccttcaa agtaaacgag tcgcggaaaa gcttggcttt
    18061 accctcgaag ctcgcataag agaccgaaag gatgttcaag gaaaccgctg tgacagtctg
    18121 atatatggct tgctgaagag cgagtgggag gaataagatg agcgatgtaa aagaggaagt
    18181 aagctctcta tctgagaagc agttacgcca aattgatgtt gagtatgctg aattaaatga
    18241 tagtgatatt atcgagcgat tagcttattt agaaattaac aacaatgaaa aacgtattgt
    18301 catctctgat attgaaccaa ccaaggaaat aatgtcagtc tcggaccaaa tttttgagat
    18361 tcaaaagaat tttcaaaaaa tcaagaatat gttcgaattg tttatttcag atgtctcgga
    18421 ttttttaagt attaaaaata aacttgagtc aaaggaatta gaaattgaag aggcagatgt
    18481 aaatcgtttc atgattcatt tattatccag tggaaaattg tttgtcgatt ttaacgaaaa
    18541 ccaaattaaa caaaaatatt ccaaagatag tgaggagttt gattgtatac atggttttgc
    18601 aagctatcag tatgatatca attttactta tcgattttgc cattctttga gaaattattc
    18661 ggaacatact gacttaccaa taaatgaggt aaaagctgtt agcccagatg atgagactgt
    18721 tataatagat ttctatattg atttagatta tcttttaaat tccaacttta aatggaaaaa
    18781 attgaaaggg gagttgataa aactaaacca agaaacatct aagattgacg ctatagctct
    18841 agtgaaagaa tactttaatg ctcttacaga gctctatggt aattataata agttgttttt
    18901 aaagttaaac cataatacat tagtagatat taaatcaaag ttggaatcat taaaattgaa
    18961 acactctagg tattatattt caaagataag caagtatgat cttaaatata atcctggaaa
    19021 ttatactatg tcaccacttg cagcatttgc tgaaattgaa gagatttata ttgaactttc
    19081 aaaaattggt ttggttaaaa ttgtcaataa aagtaattaa ggagaacaca catgtctaaa
    19141 gaactttcat ctaaatacaa tccagccgag gttgaggctg gtcgttacca aaaatggctt
    19201 gatgcggatg ttttcaagcc ttcaggcgat caaaaggcta agccttattc aatcgtgatt
    19261 ccaccaccaa acgtaactgg gaaacttcac cttggtcacg cttgggatac gactttgcag
    19321 gatatcatca tccgtcaaaa acgcatgcaa ggctttgata ccctttggct tccaggtatg
    19381 gaccacgctg gtattgcgac tcaggctaag gttgaggagc gcttacgtgg tgagggtatt
    19441 acgcgttatg acctaggtcg tgagtctttc ttgacgaagg tctgggaatg gaaagacgaa
    19501 tatgccacta ccatcaagga acaatggggc aagatggggc tttctgtaga ctattctcgt
    19561 gagcgtttca ctcttgatga aggtttgtca aaagctgttc gtaaggtctt tgtgaacctt
    19621 tacaagaaag gctggatcta tcgtggtgag tttatcatca actgggaccc agcagctcgc
    19681 acagcccttt ctgatattga ggtgattcac aaggatgtag aaggtgcctt ctaccacatg
    19741 aattacatgc tggaagatgg ttcacgcgcc cttgaagttg ctacaactcg tcctgagact
    19801 atgtttgggg acgttgcggt tgcgattaat ccagaagacc cgcgctacaa ggacttgatt
    19861 ggtaaaaacg tcatccttcc aatcgctaat aaactcatcc caatcgttgg agatgagcac
    19921 gcagatcctg agcttggtac tggtgtcgtg aaaatcacac ctgcccacga tccaaatgac
    19981 ttcttggttg gccaacgtca taacttgcca caagtcaacg tcatgaacga cgacggaact
    20041 atgaatgagc ttgcctttga attttcaggc atggatcgtt ttgaagctcg taaggcagtc
    20101 gttgctaagt tggaagaaat cggtgccctt gtcaaaatcg aaaaacgtgt ccacagtgtt
    20161 ggtcactcag aacgtacagg tgtcgtagtt gagccacgct tgtctactca atggttcgtc
    20221 aagatggacc aattggctaa gaacgccatt gctaaccaag acacagagga caaggtcgaa
    20281 ttctacccac ctcgtttcaa cgataccttc cttcaatgga tggaaaatgt ccacgactgg
    20341 gttatctctc gtcagctttg gtggggtcac caaatccctg cctggtacaa tgctgatggt
    20401 gaaatgtatg tcggcgaaga agctccagaa ggtgacggat ggactcagga cgaagacgtc
    20461 ttggatactt ggttcagttc tgccctctgg ccattttcaa ccatgggctg gcctgaagtc
    20521 gactcagaag actttaaacg ttatttccca acttcaacct tggtaacagg ttacgacatc
    20581 atcttcttct gggtatctcg tatgatcttc cagtccttgg aatttactgg tcgtcagcca
    20641 ttccaaaacg tgcttatcca cggtctcatc cgtgacgagc aaggacgcaa gatgtctaaa
    20701 tctctcggta acgggattga cccaatggat gtcatcgaga aatacggtgc tgatgccctt
    20761 cgttggttcc tttcaaacgg ttccgcacca ggtcaagacg ttcgtttctc ttacgagaaa
    20821 atggatgctt catggaactt tattaacaaa atttggaaca tttctcgcta tatcctcatg
    20881 aacaatgaag gtttgacgct ggatgtggcg catgacaatg tcacaaaagt tgcaacaggt
    20941 gaggctggta atgtgacgga ccgctggatt ctccacaatc tcaacgaaac cattgcaaaa
    21001 gttactgaaa actttgataa gttcgagttt ggtgtggctg gtcatatcct ttacaacttc
    21061 atctgggaag aatttgccaa ctggtatgtt gagttgacca aggaagtcct ttatagcgat
    21121 aacgaagaag agaaagtcat cacacgttct gttctactat acactttgga caagatcctt
    21181 cgtctccttc acccaatcat gccatttgtg acagaggaaa tctttggaca aatctcagaa
    21241 ggatctatcg ttacagcaga atacccaact atcaacccag cctttgaaga ccttgctgct
    21301 cacactggtg tggaaagcct taaagacttg atccgtgccg ttcgtaatgc gcgtgcggaa
    21361 gtaaacgttg ctccaagcaa gcctatcact atccttgtta agacaagcga tagcgacttg
    21421 gaagccttct ttaacagcaa tgtcaactac atcaaacgtt tcacaaatcc tgaacacttg
    21481 gaaatcgcat caaccatccc tgcacctgaa ctggctatgt caagcgtcat cacaggagcc
    21541 gaaatcttct tgccactggt agacctcttg aatgtcgaag aagaattggc acgtctggaa
    21601 aaagaacttg ccaaatggca gaaagaactc gacatggttg gcaaaaaact cagcaacgaa
    21661 cgcttcgtcg ccaacgctaa accagaagtt gtccaaaaag aacgcgacaa gcaagcagat
    21721 taccaagcta agtatgatgc gaccgtagca cgtattgatg agatgaagaa gttggtgaaa
    21781 taaacacaga aacacggtga tgagccgtgt tttttggtat aatgaaatca atatctattg
    21841 atggagaaag tgatgtccaa acaccctcat tatgaattgt taaatttaat tggctacggt
    21901 cttgccaagt ttgacaagct ttttataaaa gaatttcaat gctctagcaa gtcggagttt
    21961 tatcgctatg tggtttctct gggaattgct gaaacaactg gagttgtaaa aaatagaatg
    22021 gatttatttg atccttattt tgacaataat cgaaaaggtt ggtggcagaa agctgaagtt
    22081 tatcgttttc gtaaagattt aattgatatg atgtttggaa atgaagatgt tcatagttat
    22141 gctgaaatag ttaaaatgtt acttgccagt gaagggaaga aaacaggcat aaccatcgtt
    22201 gaaaaaccaa tagttcgaac taaattcaaa cgtctacagg aaacgggaat ggaggctgag
    22261 aattatttta tccttcattt tgataaagaa gaaaaattcc aaggtggaca gttaaccgat
    22321 gcccgtcttt atggtgatgg atatgacttt caggtagatg tccaagagta ttcttacctt
    22381 gccgaagtaa aaggtatccg aaaatctaag gggcgtgtgc gtttaactgc aaaagaattt
    22441 gaaaaagtca aggagtttca atcggatttt attttatcct tggtcacaaa tctagatgat
    22501 attccaaagt tagtgttaat cgataatcct ttaaaacatt ttgagtttaa aaagaatatt
    22561 atcaaaaatg aaatcattga atatagaagc gtagaggatt tgtattagtt cccccttaac
    22621 ttttccagtt gaaggaacga gaagtcttga caggtcaacg acttaatgaa ctggaaatca
    22681 acggtattcg tttgactaag ttttaagatg gcgaaatcgg tattgaattt atcagtagtg
    22741 ctgattataa ctctttt
//
LOCUS       DAVMJI010000032        22705 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.032, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000032 DAVMJI010000000
VERSION     DAVMJI010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22705
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.032"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(45..398)
                     /locus_tag="VYR58_001562"
     CDS             complement(45..398)
                     /locus_tag="VYR58_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV3622692.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLAGAAGRIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            1162..1482
                     /locus_tag="VYR58_001563"
     CDS             1162..1482
                     /locus_tag="VYR58_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV3622693.1"
                     /translation="MQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(1535..2122)
                     /locus_tag="VYR58_001564"
     CDS             complement(1535..2122)
                     /locus_tag="VYR58_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV3622694.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            2364..3035
                     /gene="sdaAB"
                     /locus_tag="VYR58_001565"
     CDS             2364..3035
                     /gene="sdaAB"
                     /locus_tag="VYR58_001565"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV3622695.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            3044..3916
                     /gene="sdaAA"
                     /locus_tag="VYR58_001566"
     CDS             3044..3916
                     /gene="sdaAA"
                     /locus_tag="VYR58_001566"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV3622696.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            3938..4570
                     /locus_tag="VYR58_001567"
     CDS             3938..4570
                     /locus_tag="VYR58_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV3622697.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            4620..4832
                     /locus_tag="VYR58_001568"
     CDS             4620..4832
                     /locus_tag="VYR58_001568"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622698.1"
                     /translation="MKIKEQTRKLAAGSSKHCFKVVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVVDRTDEVSNHIRQGDVDVV"
     gene            complement(4918..6768)
                     /locus_tag="VYR58_001569"
     CDS             complement(4918..6768)
                     /locus_tag="VYR58_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV3622699.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(6810..7967)
                     /locus_tag="VYR58_001570"
     CDS             complement(6810..7967)
                     /locus_tag="VYR58_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV3622700.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNML"
     gene            8025..9191
                     /locus_tag="VYR58_001571"
     CDS             8025..9191
                     /locus_tag="VYR58_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV3622701.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            9330..9656
                     /locus_tag="VYR58_001572"
     CDS             9330..9656
                     /locus_tag="VYR58_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV3622702.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            9643..10236
                     /locus_tag="VYR58_001573"
     CDS             9643..10236
                     /locus_tag="VYR58_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV3622703.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            10229..11140
                     /locus_tag="VYR58_001574"
     CDS             10229..11140
                     /locus_tag="VYR58_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV3622704.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDFITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            11202..12266
                     /locus_tag="VYR58_001575"
     CDS             11202..12266
                     /locus_tag="VYR58_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622705.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADFDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(12444..13304)
                     /locus_tag="VYR58_001576"
     CDS             complement(12444..13304)
                     /locus_tag="VYR58_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV3622706.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIYLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(13426..14412)
                     /locus_tag="VYR58_001577"
     CDS             complement(13426..14412)
                     /locus_tag="VYR58_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV3622707.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(14684..16159)
                     /locus_tag="VYR58_001578"
     CDS             complement(14684..16159)
                     /locus_tag="VYR58_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV3622708.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKATDSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(16417..17340)
                     /locus_tag="VYR58_001579"
     CDS             complement(16417..17340)
                     /locus_tag="VYR58_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV3622709.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(17354..18283)
                     /locus_tag="VYR58_001580"
     CDS             complement(17354..18283)
                     /locus_tag="VYR58_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV3622710.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(18602..18952)
                     /locus_tag="VYR58_001581"
     CDS             complement(18602..18952)
                     /locus_tag="VYR58_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622711.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRNILQTVKDAI
                     VSLESIKESQSATKDGGQTVGKETVDKDVLENSQEELQKAVLFLADEKGSEHTAAELI
                     DNLKEVIAKLKANA"
     gene            19032..19169
                     /locus_tag="VYR58_001582"
                     /pseudo
     CDS             19032..19169
                     /locus_tag="VYR58_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(19273..19428)
                     /locus_tag="VYR58_001583"
                     /pseudo
     CDS             complement(19273..19428)
                     /locus_tag="VYR58_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(19614..20225)
                     /gene="rpsD"
                     /locus_tag="VYR58_001584"
     CDS             complement(19614..20225)
                     /gene="rpsD"
                     /locus_tag="VYR58_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV3622712.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(20420..21472)
                     /locus_tag="VYR58_001585"
     CDS             complement(20420..21472)
                     /locus_tag="VYR58_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV3622713.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(21469..22167)
                     /locus_tag="VYR58_001586"
     CDS             complement(21469..22167)
                     /locus_tag="VYR58_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3622714.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(22334..>22705)
                     /locus_tag="VYR58_001587"
     CDS             complement(22334..>22705)
                     /locus_tag="VYR58_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV3622715.1"
                     /translation="LDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHA
                     TGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGF
                     LGLALAGLLGGLGLKNKKEEN"
BASE COUNT         6753 a         4884 c         4197 g         6871 t
ORIGIN      
        1 ccaacatacg ataatgtgta tttttcgaat cttatctaca ttactcatct tactgtcgca
       61 gatatgaatc catcccaagg ataagggttc ccgctaatat cacaacctct attaagagca
      121 ccatatccaa tacagtaagc tattcttcct gccgccccag ccaatacacc tgctgctgca
      181 ccaataagcc aacctccaag gcctccaact ttaatatagt ttattagttt tttggttaaa
      241 actgcagctc cagctaatgc tataaaagtt cctggactca tagctaaagc tgcgcaaatt
      301 ccttgacaag cacgcttgct taaataagct cccccatcaa ggtacatcat ctcttcttca
      361 tcaatcacaa cataattatt tggtaataca agttccattt attttctcct tttttattaa
      421 gcatggttag gatggtttcc taacaagtga tcgcaggctt tgtttagtta cctaaattag
      481 acttcctttc tttatcttat tttaaatatt taaaaccagt tactgcttga agcttaacag
      541 tttacttaat tcaaataaca gctaatcact gattccctga ttttatcaaa tatactaata
      601 acaacaattg tgatacgatc atcattataa gaacaacatt taacgaatca aagtttttcc
      661 gagataataa taaagcaaca gcaagcagta ttattactaa agattgaata actactatta
      721 ctcttaacat tttatcctcc actaacaact caagctccct tacattatat cgaccagccc
      781 catggaaaga ttatagctag actaatcaat gatataatac atactagaat acaaaatatt
      841 tttttattca tactttttct cctatcttta ttttctacct acatagtacc tcttattaag
      901 ctcatttcaa aattacgtta acttttttca cgaaaaggag aaaattatgc gttatgatta
      961 tggatagcgc tttcaaattt ttaaactcct atcccgtcct tttatctata taataagcat
     1021 aagcgaaaat ataataactg tcaagtaact gaagtgaatt ttataaaaaa attacaagcc
     1081 aaatttgtaa agtttacact aagccgctag ggcaatcgtc tatcagaatg tccgtttatt
     1141 tgtcaataat ccgagaaaat cttgcaacgc ttagaagtct ataaaaacta tcaacattta
     1201 tatgacttgc gaatgacaat tctattaaac ctttccacac tctatctata caatcaagat
     1261 aaaaacatgt gtaagcaaat ctgctacact ttactggagg acgccaagaa taagaaaagc
     1321 tacgataggc tggctatctg ctatgtccgt attgggattt gtagggatga tgcgaaactt
     1381 atccaaaaag ggttctcact cctagagctg accgaggaaa cttctatgct gtctcatctc
     1441 aaaaaagaag tagagaccca ttatcaacca aagaaattat aaaaaaagtc gagggatttc
     1501 ctcgactctt tacatattat ttgttcgtta gttcttaata ccagccattg ttaagccaga
     1561 agtttttagc agcagtccat gaaccgtaac gtcctgcaac gtaggcatct gctacacgtt
     1621 cttggttttc agctgagtag tcaccgttca ggtatgaatc tgttaattgg taacgtccga
     1681 tataacgtcc atttgtagct gtatagctac cacctgattc tttttgagcg atccattctt
     1741 tggcttctgc ttcagatccg cttacagttg aaacaactgt ttcacttact actggagttt
     1801 ctgctactgg agctgaaaca gtttcatctt gagcggctgg tgccgcataa gtagctggcg
     1861 ctggtgttgc aacaggcgct acagggccat cgataaccaa ctcttgatca acataaatca
     1921 aatgaatgtt atcaatgtgg ttgttttctg ccaatttttc aactgttgtg ttgtgagttt
     1981 cagcgatttc tgaaagtgta tcaccttctt taacagtgta agttgatgat tcttgagcag
     2041 atacaaatga tggagcaaat actgcaaaca aggcagctac tcctgcaaga gttgctttaa
     2101 tctttttagt tattgatttc atattcgaaa attctccttc tttctatagt tctatcatac
     2161 cctttaaata ttaccgtttc ttgacacttt tatgtagaaa tattacaaaa ttatttttta
     2221 tttccctaaa taaggtgttt tttgtcataa aagatactat ttttatgcta tttgaggtat
     2281 tagaaaggtt ttcatccaca attaaagcca agcccctcat tctttgatat aatagagata
     2341 agaattttta taaggggaaa ctgatgaaat cacttcgttt tcaatctgtc tttgatatca
     2401 tcggaccagt tatgattggc ccatctagta gccataccgc tggtgctgtt cgtattggga
     2461 agattgtctc ttccattttt gatgatactc cgacagaagt tgaattccaa ctttttaact
     2521 catttgccaa gacctatcgt ggtcacggaa cagacctagc ccttgttgca ggtattttag
     2581 gaatggatac agatgatcct gaaattccaa atagtctgga aattgcccac aagcgtggta
     2641 tcaagattgt ctggaccatt cagaaagaca gcaatgcccc tcaccctaac accactaaaa
     2701 ttactgttaa aaatgcccac aagaccatca gcgtgactgg tatttctatc ggtggaggaa
     2761 atattcaggt aaccgaactc aatggttttg ccgtctctct caatatgaat acaccgacta
     2821 tcatcatcgt tcatcaagat attccaggta tgattgccct tgttacagag gcgctttccc
     2881 gctatggtat caatatcgcc cagatgaatg tcactcgtga aaaagctggt gaaaaagcca
     2941 ttatgattat cgaagttgac agtcgcaact gtgatgaggc tatcgaagaa attcgaaaaa
     3001 tccctcatct ccacaatgtc aatttcttta aataggagga agcatgtttt attctatcaa
     3061 agaattggtc gagcaagcag atctggactt tcaaggaaat gtcgcagaac tcatgattac
     3121 aacagagttt gaattgaccg gtcgcgaacg tgaagaagtc ttccttctca tggaacgcaa
     3181 tctggaagtt atgaaagcct ctgtccaact tggcctcaat gaaaataaat ctcgtagtgg
     3241 cctgacaggt ggagatgctg ccaaattgga tcactacatc gaaaacggaa aaactctgtc
     3301 agattatacg attctctcgg ctgcccgaaa tgccatcgca gtcaatgaac acaatgccaa
     3361 aatgggcttg gtctgtgcca ctccaaccgc tggaagtgct ggctgtctgc catccgttct
     3421 cactgctgct attgaaaaat tagacctcag ccacgagcaa caattggatt tcctctttgc
     3481 tgctggtgcc tttggactag tcatcgcaaa caatgcctcc atctcaggtg ctgagggtgg
     3541 gtgtcaagct gaagttggtt cagcctctgc tatgagtgct gccgccttga ctctggctgc
     3601 aggtggaaca ccttatcagg ccagtcaagc tattgccttt gtcattaaaa atatgctagg
     3661 cctcatctgt gaccctgttg caggtttggt cgaagttccc tgtgtcaaac gtaatgccat
     3721 gggagctagc tttgctttca tcgcagcaga catggccttg gcaggtatcg aatctaaaat
     3781 ccctgtggat gaagtgatcg atgccatgta ccaagtagga gcaagcatgc caactgcctt
     3841 tcgtgaaaca gctgaaggtg gactcgctac cacccctact ggtcgtcgcc tccaaaaaga
     3901 aattttcgga gaataagctt atcaaatagg agaaaccatg acctctatca cagcgatttt
     3961 tttcgatttg gatggaaccc tcgttgatag ttctatcggg attcacaatg cctttaccta
     4021 tacctttaaa gagctggggg tgcctagccc tgatgccaaa actattcgtg gttttatggg
     4081 accacctctc gaaagtagtt ttgcgacctg cctgtccaaa gaccaaattt ctgaagccgt
     4141 gcagatatat cgttcttact ataaggcaaa aggcatctat gaagctcaac tctttcctca
     4201 gattatagac ttgcttgagg agttatcgag cagttatcca ctctacatca ccacgacaaa
     4261 ggatacatct actgctcaag acatggcaaa aaacttggaa atccatcatt tctttgatgg
     4321 catttatggt tctagccctg aagcacccca taaggcagat gtcattcacc aagccttgca
     4381 gacacatcaa ctagcaccag aacaagccat catcatcgga gataccaagt ttgatatgct
     4441 gggagctcga gaaacaggta ttcagaaatt ggccatcact tggggatttg gagagcaagc
     4501 agatctacta aactatcaac ctgattatat cgctcacaaa cccttagaag ttttggcgta
     4561 ttttcaatag catagactgg gtaacaattc catttcagaa gaaaatgaag taatactcaa
     4621 tgaaaatcaa agagcaaact aggaaactag ctgcgggcag ctcaaaacac tgttttaagg
     4681 ttgtagatgg aactgacgaa gtcagctcaa aacactgttt taaggttgtg gatggaactg
     4741 acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagtaacc
     4801 atatacggca aggcgacgtt gacgtggttt gaagagattt tcgaagagta taagtctcta
     4861 cataataaaa cgcatattac caaggttgtg taacttgata ctatgcgttt ttctttttta
     4921 ttcaatgtgg gttgtttgat tagcaaaggc gataatagct tgcttcaact catctccact
     4981 gagagtgcgg aactctccaa tcttttgatt gatggattct aaaggcatga cattaacctt
     5041 accaacgaaa atcttatcca taacttgatt atcaacgagt tcggttgata ccaagagttc
     5101 ttcgtagagt ttttcacctg ggcggattcc aacttcaacg attggaattt cactttcagt
     5161 gtggccactt agaagcacca tcttcttggc caagtcataa atcttgactg gtttgcccat
     5221 atcaaggata aagacttccc catctttggc ataagcacca gcatggataa ccagacggct
     5281 agcttctgga atggtcataa agtaacgggt catgcggaag tctgtcaccg ttacaggccc
     5341 accttcagca atctgacgtt caaagactgg aatgacacta ccacggctac caagaacatt
     5401 cccaaaacga actgcacagt aggttgattg gctacgttgg ttaaagccag tgacaatcaa
     5461 ctccgccacg cgcttggttg ctcccataac atttggtgga ttgactgcct tatctgtcga
     5521 aatcataacc atcttagaca ctttagcttc atcaacagcc ttagcaacat tgtaagttcc
     5581 acggatattg tttttgaagg cttcttttgg attgcgctcc atcataggaa catgcttgtg
     5641 ggctgccgca tgataaacaa tagcaggttt gtactgctca aagacttgca acaaacgatc
     5701 atagtcttga atgtccgcaa tcacaggtac ataatcaatc ccttggaact tacgaatcaa
     5761 ttcatgataa acaaggtaga ttgagttttc cccatgaccg agcaagacaa tgcgttcagg
     5821 attgaagcga ctaacttgac gacagatttc agaaccgatt gaacctccag ctcctgtgac
     5881 taagatggtc ttacctgtca gttctgcacc cagacgcgat tcgtcaagac ggatttcctg
     5941 acgacccaaa aggtccgtaa tatcaatttt ttggaagcca gtacctgctt ggtgaaggcc
     6001 ctgaacaaca gtttcaacct taggcatctt gtaacatttg acacccagct tattacacat
     6061 ctgcaagata cgctcatatt ctgacggatc cagcgacgga atcgcaacga tgacacgctc
     6121 gatttgatgg cgtttggcta attcaggcag attgtcataa gagcccaaaa caggaatacc
     6181 accaagtttt tgaccctttt tcttagaatc cttatccaaa ataccgacca gttctaattc
     6241 actggttgga tgttggtaac tatccataaa aagagcccca ccatcaccgg caccaatcaa
     6301 gaaggtccga cggtgttctc catcaccact accttttttg cgtctggagt agattaactg
     6361 ccaagtaatc cgtggcaata aaatcaagaa ggtactcaac aagataaaga gaatgatgaa
     6421 acggatggag aagagtggca agaaggcata acagatacta tatgacaaga cactgctagc
     6481 agtcacacca aaaaagattt tcatgaaatc cgtaatcttg ctgtaacgac taatgctcgc
     6541 gttcaacccc caaaaaccaa tcatcaattg atagaacagg aaggccaaac tcgtatagat
     6601 aatgtagtca acaggtgctg gattaatcag cccataaaat aaaatataag atacaatgat
     6661 ggaaaccacc atactgaaaa tatcaaatat tccccagaaa acctgctttt gttgtttatt
     6721 taaaatttcc accagatcaa tcacataatc tgttagtttt ttattcatag aaatctactc
     6781 ctccttaaaa gagttttact atattgttat tatagcatat tttgatttat ttggcttatt
     6841 ttatccaaat aaattattgt tctcttgtac tccttcttcc atttaaatcc tctaattaaa
     6901 cctacaatcg tcccaaggcc ataagcaaag tgaatggaaa ataaaagaaa gggcatcaca
     6961 attagaaatc catttttatg ttttaataaa gtcagcaaag tgagtaatga caaaagtaga
     7021 aaataggcac ctaatagtaa agttatgaat acgaatgtga tcggtaacaa tgctagacta
     7081 aacacaagac tcaaaacaaa taaacaagga acatagtgaa ataatgataa acacttaaac
     7141 tgaacatgac ttgtcaagcc aatccacaaa ccatttgaat acttttgatg cagcattttc
     7201 ttgaatgttg gtcgaatata ctgataagat agaatacttg ggctatagcg gattttataa
     7261 ccatattctc gaattctata atgaatatca ttatcttcag ttcggccaag ttgctcattt
     7321 actaaaccaa ccttctggaa aacctctcgt ttatacattc catgaaaaat agaagaaaca
     7381 tatctatcct cagaactatt tcgataattg gcaatgctac tgccaaacat attttcctca
     7441 acaagatgca aggtctctgc ccattttcct tttccttcga caatcgtcgg tctaggcccc
     7501 ccacagacaa attcaccttg ttgaataata gccacattgt tcattacaaa agtctcagta
     7561 acttttgaat gagcatcaat ttttaaaata aggtccccta cagaatgttt aactcccagg
     7621 ttaaaaccac tagcttgatt tttcttagga ttgttataca atctaattga gttaaactct
     7681 gtatcttcct ttataaattg ctgaatgata gctgtggtcc catctgtgga catagcattt
     7741 ataaatagaa tttcaatatt ctctttagga taggtttgat tttttaagtc ttcaattaga
     7801 ccaggcagat atttttcttc attgtatgca ctgattacaa tggatacgag aagactttca
     7861 acattttgag tcactactac tctcctgaat ttttccttcc accattctat cataattttc
     7921 aagactttcc catttttatc ttgaaagcca gaaaccttac ttgacattat agtgaaaaag
     7981 ccttaaaata agctgttatt aaaatcagct agaagaggta ttatatgaaa aagcaatcac
     8041 tcttttttgt tccaggtatt atcctgattg gtgtttcctt gcgaactcct tttactgttt
     8101 tacccattat tttgggaaat atttcgcaag gtctggaggt agaagttagt tcgcttggtg
     8161 tcttgaccag cctgcctctc cttatgttta ccctcttttc accattttct acccaactgg
     8221 ctcagaaaat cggcttggag catctcttca cctacagcct cttcttcttg accatcggct
     8281 cacttattcg actaatcaat ctgcccctgc tctatctagg aaccttgatg gttggggcaa
     8341 gtgtcgcagt catcaatgtc ctgcttccta gtcttatcca agccaatcaa ccaaagaaaa
     8401 ttggttttct gaccacctta tatgtaacgt ctatggggat tgcaacggct ctggcttcct
     8461 atctagctgt gcccattaca caagccagtt cttggaaagg acttatcctt ctcctcacgt
     8521 tactctgtct agcaactttt ttggtctggc tcccaaatca ccgctataat catagactag
     8581 ctccacaaac caaacaaaaa agtcaaataa aggtcatgcg taataaacag gtttgggcaa
     8641 ttattatctt ttcaggtttt caatccttga tcttttacac cgtcatgacc tggttaccta
     8701 ccatgtctat ccatgcaggt ctatccagtc acgaagctgg cttgctgact tctatcttat
     8761 ctctgattag cattcctttt tcaatgacca tcccaagcct gacaaccagt ttatctactc
     8821 gcaaccgtca gctcatgctc actctggttt cactagctgg tgtggtcggc atttccatgc
     8881 tctttttccc aatcaataat ttcatttact ggcttaccat ccatctcctc atcggaaccg
     8941 caaccagcgc cctcttccct tatctcatgg tcaacttttc actcaagaca agcgcccctg
     9001 aaaagacagc ccaattgtcc ggcctatctc aaacaggagg ctatatccta gcagcctttg
     9061 ggccaaccct ctttggttac agttttgacc tgttccactc ttgggtacca gctgtagctg
     9121 ccctcttgct catctatatc ctgatgactg tggccctctt tacagtggac agagcggata
     9181 agatccttta aacttctagt tttagctaga agttttttat atataaaaat tttacacatt
     9241 tctcttgaca gggctttctt ttagatgtac aatgtatgtg tagaaaaatt atatataaaa
     9301 atcttacaca ttagaaaagg aggtttccca tgtactttcc aacatcctct gccttgattg
     9361 aatttctcat cttggctgta ctggagcagg gtgattctta tggttatgag attagccaaa
     9421 ccattaagct gatcgctaat atcaaagaat ccacactcta tcccattctc aaaaaattgg
     9481 aaggcaatag ctttctgaca acctattcta gagagttcca aggtcgcatg cgcaaatact
     9541 actccttgac aaacggtggt atagagcagc tcttgaccct aaaagatgaa tgggcactct
     9601 atacagacac catcaatggc atcatagaag ggagtatccg ccatgacaag aactgaatac
     9661 ctgactcagc tagaactcta tctcaagaaa ctacctgaag ctgaccgtat cgaagccatg
     9721 gactatttca gagagctctt tgacgatgct ggagtcgaag gagaagaaga actcatcgct
     9781 agtttgggaa ctcccaaaga agcggcccac gaagttctat ccaatcttct cgataaaaaa
     9841 atcaatgaag cacccgctca aaaaaataac cgacaaattt tacatatcgc cttgttagcc
     9901 ctccttgcag cacctatcgg cattcctctg ggaatcgcca tcctcgtgac cctgttcgca
     9961 atccttgtag ccgctttgac tgtcattctg gctttctttg cagtttccat actgggtatc
    10021 atcggcggat tcctattttt agttgaaagt ttcactatcc tcgcccaagc caaatcagcc
    10081 tttatcttga tttttggttc tggtttactg gctatcggtg cttcttcgct agttttactt
    10141 ggcatttcct atgtagctcg cttcttcggt ctactcattg ttcgtctggt acaatttgtt
    10201 cttaaaaaag gaaagagagg taatcagcat gcgtaaatgg acaaaaggat ttctcatctt
    10261 tggtgtggtg actaccgtta tcggctttat cctgcttttt gtaggtatcc aatctgacgg
    10321 gattaagagc ctactttcca tgtccaaaga acctgtctat gatagccgta cggaaaagct
    10381 aacctttggc aaggaagtcg aaaacctaga aattactctc caccaacaca cgctcaccat
    10441 cacagactct ttcgatgatc aaatccacat ttcttaccat ccatctcttt ctgctcacca
    10501 tgattttatc accaatcaga acgatagaac tctgagtctc actgataaga aactgtctga
    10561 aactccgttt ctctcttctg gaattggtgg gattcttcat atcgcaagta gctactctag
    10621 tcgttttgaa gaagttattc tccgactacc aaaagggaga actctaaaag ggatcaacat
    10681 ctcagccaat cgcggacaaa ccaccatcat aaatgctagc cttgaaaatg cgaccctcaa
    10741 tacaaacagc tatatcctcc gaattgaagg aagtcgtatc aaaaacagta aactcacaac
    10801 gcccaatatc gttaatatct ttgatacagt tcttacagat agtcagctag agtcaacaga
    10861 taatcacttc cacgctgaaa atatccaagt ccatggtaag gttgaactga ctgccaaaga
    10921 ttatctcaga atcatcctag accagaaaga aagccaacga attaactggg acatctcaag
    10981 taactacggt tctatcttcc aattcacaag agaaaagcct gaatcaagag gtacggaatt
    11041 aagcaaccct tacaaaactg aaaaaaccga tgtcaaggat caactcattg cgagatctga
    11101 tgataatatt gatctaatat ccacaccaag cagacgttga caaaaacgct tacatctgct
    11161 actatggaag catatttatc taaccaaaag gaggttctac catgaaacaa gaatggtttg
    11221 aaagtaatga ttttgtaaaa acaacaagca agaacaagcc tgaagagcaa gctcaagagg
    11281 ttgcagacaa ggctgaagaa acgatagccg atttcgatac accaattgga aaaaatactc
    11341 aagtagagga ggaagtctct caagctgaag tcgaactgga aagccagcaa gaagagaaaa
    11401 ttgaaactcc tgaagtcggt gaagcgagaa cagaaataga agaaaagaag gcatctaatt
    11461 ctactgaaga agagtcagac ctttctaaag aaacagaaaa agtcactata gctgaagaga
    11521 gccaagaagc tcttcctcag caaaaagcaa ccacgaaaga gccgcttctt atcagtaaat
    11581 ctttagaaag tccttatatc cccgaccaag ctccaaaatc tagggataaa tggaaagagc
    11641 aagtgcttga tttttggtct tggctagtgg aagcgatcaa atctcctaca agtaagtttg
    11701 aaacaagtat cacacacagt tacacagcct ttctcttgct cattctgttt tctgcatctt
    11761 cctttttctt tagtatctat cacatcaaac atgcttacta tggacatata gcaagcatta
    11821 acagtcgctt ccctgagcag ctagctcctt taactctttt ttctatcatc tctatcctag
    11881 tagcgacaac actcttcttc ttttcattcc tcttgggtag tttcgttgtg agacgattta
    11941 tccaccagga aaaggactgg acactagaca aggttctcca acaatatagt caactcttgg
    12001 caattccaat cttcctcact gctattgcta gtttctttgc tttctttgat agcctacgat
    12061 ttacagccct cttgtgtgtg attagcattg gaatcattct gcttgccagt ctccatatca
    12121 ttacaagacc aagtcaagca agtgaaaccg actccttcta tcaattattc ttgtctgtcc
    12181 ttgtgaacgg agttattatc ctcctcttct ttgtagctga agtggcactg attggagatt
    12241 atcttcgtat cttggccttt ctttaaactt catactcttc gaaaatcaaa ttcaaaccac
    12301 gtcagcttcg ccttaccgta ctcaagtaca gcctgcggct agcttcctag tttgctcttt
    12361 gattttcatt gagtagcaat cctgtcatcc ttggcaggat tttttctatg tcaaaaaagc
    12421 aagtcgattg acctgcttct gctttacttt tcttgtgcta atgttttaaa atcttgtcct
    12481 aggatgggtt gtatttctat ttgattggcg tctagttggt ggtaaaaaga tgggggtaat
    12541 acctctaaga attttgcata gtccaagcga gctatggatt catagtcttc tggtttagag
    12601 ccgtctcctg tgatttgaac caagtaaatc tcccactgga cttccttatc caccaattgc
    12661 tcaatatagg ctgcaggaac aaacggttct ctcggtaaaa ctgtcttgac tccttgagct
    12721 aaatggtaaa cgccatgcac ttttccttct ccatcctgat agaaggaaac tcttgcaaag
    12781 taggcatctg tctcttgaac cgcacgcaca cgcgcttcaa actgagccaa gccatctgcc
    12841 tctaaaaagc ttttcaagtt ctcacgacta aagaaaatag gattaaaaat tccttggcaa
    12901 atcgtaaaac gagctacagg gtctgctaga taggcttgaa tacttgcttg gaaataagct
    12961 tcaaaatcaa aaccatctag cccttcaata tcagtccctg tataagcaag caaagcatct
    13021 aaaaatgact tgataatctg ccagtctgtc tttgttagta ggtcaggaag atcgacacgg
    13081 taagcctttt gaccatcagc ataactgacc ttaaagagaa attgtgattg ccccactatc
    13141 gcacactcaa tatactcgag acgattaaga ggctgacgaa gatagactac atcatagcta
    13201 tgtgactcca aaccgtctag caaggccaag atcgacttgg cattcaaaat ctcttgttct
    13261 cctaaaatgc tctgtttatt tggaataaaa aatgtttttg ccataactgg actcctttga
    13321 aatcgtttac atacagtata ccttattttc ctgaaagata caaaaacaaa ctttagattt
    13381 ttgagtacaa agcatagaaa aacagcccct gaggactgtt tgatcttata cagtagctgc
    13441 ctgatccaag ctttcaccga tagcggctag gcgctcaatc acttcagctt gtgtcaattc
    13501 attttttgaa acatagcggt tacgtgggtg aacacggcac tcgtgtgagc atccacgaag
    13561 gtacttgtct tcattttctt ctgatgtcaa gatacgacgg ttacagaagg gatttccaca
    13621 gttgacataa cgttcacatg gtgttccatc aaaccagtct ttccctacga tggttgggtt
    13681 gacatggttg acatcaacgg caatacgctc gtcaaagacg tacattttcc catcccaaag
    13741 ctcaccttga acttctgggt ctttaccgta agttgcgatt cctccgtgca attggccgac
    13801 atctttgtag ccttcacgga ccatccagcc tgagaatttc tcacagcgaa cgccacctgt
    13861 acagtaaacc acgacacgct tgtccatgaa tttttccttg ttatcacgga cccattgtgg
    13921 taactcacgg aagttgcgaa tatctgggcg aatagcccca cggaaatgtc ctaggtcgta
    13981 ctcataatcg ttacgtgtgt caaggacaac ggtatcttta tcaagaagcg cttctttgaa
    14041 ctcttttgga gacaagtaag cacctgttgt ttcaagtggg ttgatgtcat tgtcaaagtc
    14101 gttgtcttcc aaaccaaggt ggacaatttc tttcttgtag cgaacaaaca tcttcttgaa
    14161 ggcttgttca ttttcttcgt caatcttgaa ccagagatct tccatacctg ggaggctgtg
    14221 aacgtagtcc atgtattttt gagttgtttc atagtcacct gaaactgttc cgttaattcc
    14281 ctcgtcagcg actaggatac ggcctttaag gccgattgat ttacagaaag ccaagtggtc
    14341 tgcagcaaat tgctctgcat tttcaattgg agtataaagg tagtaaagta agacacgaat
    14401 atcttttgcc ataagatttg ttctcttttc tattcttaaa ttttctaaat tttttattta
    14461 tccatactag tatacctgct tgagaaaacg aatgcaattt atttgactgg aaattgtaga
    14521 ggattctcga aatttcctga atggttaaaa taaggacaag agaaaacagg gatatctata
    14581 tccttgtgcc aaaaaaacca ctgccctccc cagatcaacc tgaggaaagc agtgattctt
    14641 attttaggag ttaggaatga atacacgaaa tcaatttagc tgattatttt ttgtttttca
    14701 agaattcatc gtattgtttt tgcatttcgt tcaatacttt ttcgtaggca ccttcagatt
    14761 tcaatttttc catcaattct ggaatcgctt tatctgggtc tacagtacca gtgttgatag
    14821 ctgtatcaaa ttgttgcatt gtgttagcaa tagctgagat ttcagatttc acattgtcag
    14881 tattaaagat aaatccaagc gctggagatt ctttagcttc tgccaattct ttcttagaat
    14941 tttcgatttg ttggtctgta acgttttcgt tgatgtaaag gatccagttg ttaccagtgt
    15001 tccatccacc catgtgagtg tttcctttgt agccatcaag aacgcgaaca cggttttctt
    15061 taccttcaat tttttcccag ttcttgcctt ctggaccgta aacaagaccg ttcaagagtt
    15121 ctgggttcgt attcaagagg ttcaagattt ccattgattt ttctttgttc ttagagttgt
    15181 ttgagatgac aaagttagca acttgtgttg tttggttttt cttgatgaag ttagtaattg
    15241 gtttgatttg gatatctttg ttggcaacac gtgaaagcaa gctgttaccg tagtcagctg
    15301 gtcctactgt ttcttcacga acgaaccaag tatcttgttg aaggtcaaag gaagtatcgc
    15361 ttgttgcgac gtcttttgga atgtagccag cttcatagaa tttgtgaaga gtcttcaagt
    15421 gttctttgaa acgaggtact tcgtaacggt ttacaacttt agtagtatcg ccttcaaggt
    15481 caataacgaa tggaagaccg tttgctactg ggtagtcaaa gttatcagat gggatgaaaa
    15541 ctttaccaat agcaaatggt actacgtctg gagctttttc tttgatttgt ttcaagactg
    15601 gctcaagagt ttcgtaagaa gtaacacctg aaatatcgat accatatttg gcaaggagag
    15661 ttccgttgaa ggcaaagttt tgagatgatg ctacgttagc tgcaactggt acagcataaa
    15721 tcttaccatt tacagtatta cccttgatat aagctggatc aagtgccttg taaaggtctt
    15781 taccttcttt tttgtacaat tctgtcaagt cagcataagc acctttttga gcatttacaa
    15841 tatagttatc tgcaaaggcg atatcatagt tttcaccaga tgatgtgata actgacattt
    15901 tcttaccata gtcaccccag ccaaggtatt ggatatccaa tttagcacca actttttctt
    15961 cgatgatttt gttggcattt gctaacaatt catccaagtt atctggtttg tcaccgattt
    16021 ggtacatttt gataacaggt ttgtcacctg aatcagtagc ttttttgctg ttacctgtca
    16081 aatttccaca agcagcaaga cctgcagcca aagcgactac actagcagat gcaaaagcat
    16141 attttttcca gtttttcatg atgaaaactc ctttttttat ttttaaactt ataaacaatg
    16201 taatgatctt atactcaatg aaaatcaaag agcaaactag aaaactagcc gcaggttgct
    16261 caaaacactg ttttgaggtt gtggataaga ctgacgaagt cagttacata tatctacggc
    16321 aaggcgacgt tgacgcggtt tgaatttgat tttcgaagag tattaacttc acacaaggga
    16381 agttgggaac tgagaaatgt tctttttcaa taagcactat tctttcacac caccgatagt
    16441 caaacctttt acaaagtagc gttggaagaa tggatataaa atcgcgattg gaagggttgc
    16501 aaccacaacc atggccatac gacctgtttc tttcggtaga gcaactccca gttgaccagt
    16561 caagccgacc gctttggcaa tgtagtccat attttgttgg atttgcatga gcaaatattg
    16621 caatggatac aagttatcac tcttgatgta aagaagggcg ttgaaccagt cattccagaa
    16681 accaagagct gtcaaaagcg tgatggttgc gatacctggt agtgacaatg gcaaacagat
    16741 ttggaagaaa atccgggcct cactggcacc atcgatacga gccgattcga gaatggcttc
    16801 tggaatggtc ttcttgaaga aggaacgcat caagatgata ttgaatggtg agagaagcat
    16861 tggaacaatc aaggcccaaa cagtgtcacc aagctgaagt acacgggtca ccatgatata
    16921 acctggtacc aaaccagcgt tgaacaacat actgagaagg acgaagatgg taaaaaatct
    16981 gcgatactta aaggttgtcc gtgaaatagc gtaggcatag gttgttgtga taaagacatt
    17041 tgtcaatgtc ccaactacgg ttacaaagac agagatgaag agggcttgta ggattttatc
    17101 cttaaactgt gccaaaaact caaaaccgtc taagccaaat tgggatggga agaagctata
    17161 gccgtattgg aggaggcttt tctcgtctgt cactgaaata atgataacga atacaaaagg
    17221 taggatacaa gagagggcaa tcaaacccga aatgatactg aagaagatat ctgctttctt
    17281 actgaaggag tgaatgccga cattatcaat tttttctttt ttaattttct tttttgccat
    17341 attctcctcc tttctagaac aaagctgagt ttggatcgac tcgtcttgca agcaagtttg
    17401 ataggataac cagaatcaaa ccaacaacgg attggtaaag accggctgct gcagccatac
    17461 cgatatctgc tgtctgagtc aaaccattaa aaacatatac gtccaaaacg ttggttacat
    17521 tgtaaagctg accagcattg tgtgggattt gatagaagag accgaagtct gcgcggaaga
    17581 tatttccgac tgcaaggatg gtcaatacag ttacaagcgg agtcaactga ggaatggtta
    17641 cgttgcgaat acgttgccac ttgctagctc cgtccactgt cgctgcttcg tagtaggttg
    17701 gatcaattcc catgatcgtc gcatagtaca tgacactgct atatccaaaa cctttccaaa
    17761 tacctaggaa aagtaggaga tagggccaga tgcccaggtc agcgtagaaa ttgacttctt
    17821 tgagaccaag actttccaat agatgattga acaccccttt atcaatattt aggaaggcat
    17881 ctgtaaagaa actgatgata acccaagaca agaagtaagg gaacaacata gaagtttgga
    17941 aaatcttcac cattctctta gaacggagct cgctgaggat aatggcaatc cctacagata
    18001 caactaaacc tagaaagata aagccaagat tgtagaggac agtatttcgt gtgataataa
    18061 aggcgtctct tgaactaaat aagaatctga aattatcgag tccgacccat ttactattta
    18121 tgatactatc tatgaaacca ttactggtca tgtggtagtc tttgaaggca accacgttcc
    18181 caaatactgg aatgtaaaag aatagaatca accagagtgc ccctggcaaa accatcaaga
    18241 gaaagatcca gttgtctctc aatgtttttg aaaacttttt cataatttcc tcccttttta
    18301 ttttgatatc catctaaaaa ttctttttta gacttttgat aacgattaca ttattagtat
    18361 actcctattt gcaggttagg ttaaactcct aattatagaa aaaactccac aaattatgta
    18421 gcagatttaa aactttatca ccactatcaa acaaatgtcc taaatcaatt gtttatttta
    18481 tctctattag cccagtgatg gcgtcactct gttataagca tccaacaacg gggtatactg
    18541 aaaaatctcc agactaggga actcagcgat agttcctaat ctggagattt ttaatatgtt
    18601 attaggcgtt tgctttcaac ttagcaataa cctctttaag attatcaatc aactctgctg
    18661 cagtatgctc agagcctttt tcatctgcca agaacaaaac tgctttttga agttcttctt
    18721 gagagttttc aaggacatcc ttatctactg tttctttgcc cactgtttgt cctccatcct
    18781 tagttgctga ctggctttcc ttaatggact ctagggaaac aatggcatct ttgactgttt
    18841 gcaagatatt acgtaaacct tgctctgtca aactatcatc tgcaaaagct ttcttagcct
    18901 ctgccaaaac cagacgtgct gaatctgtgg taggattcga tacacctgtc aatgatctca
    18961 aaagattttc taaggtttga gtctgcttac taatactaga ctaaaatcaa aaagtattat
    19021 ataacagtga tatgaaatca actaaagaag aaatccaaac catcaaaaca cttttaaaag
    19081 actctcgtac agctaaatat cataaacgcc ttcaaatcgt tctattttgt ctgatgggca
    19141 aatcttataa agagattata gaacttttat agtagtttga aataagatgt gaacatctct
    19201 atcaggaaag tcaaattaat ttatagaaat attttagcag ccaaggtgta ctgttataga
    19261 ttcaatacac tatacttggt ggtttagctc tcctgttttc tcttttagct ttaaccagcc
    19321 ataaatggta ttacgtgaga tttggaaaac gtgtgatgct tctgttatac tacctgttcg
    19381 ctcacaataa gagagaactt ttttacgaaa atctattgaa tatgccataa aaggattata
    19441 ccacattgtg tactattttt ggttcatttt actatatcac tttggactat atcggtctag
    19501 ttatgtctca acgattatag ctggatacta agagaaatca aaaaagcact aagggagaac
    19561 gtcccaaagt gcttaatatc aaggcctcaa agtctatctt attcaataaa atattacaac
    19621 attttgttgt agaattcaac gacaagtgct tcgttgattt ctgggttgat ttcgtcgcgt
    19681 tctggcaagc gagtcaatga accttccaac ttttcagcgt cgaatgatac gaatgctgga
    19741 cgtccaagag tagcttctac tgcttcaagg attgctggaa ctttcaatga tttttcacga
    19801 actgagatca cttgacctgg agttacgcgg tatgatggga tatcaacgcg tttcccgtca
    19861 acaaggatgt gaccgtggtt tacgaattga cgagcttgac gacgagtagt cgcgagacca
    19921 agacggtaaa caacgttatc caaacgacgt tccaaaagaa gcataaagtt gaaacctagg
    19981 attccgcctt tgatttttgt agcttgtacg aacaagttac ggaattgttt ttcacctaca
    20041 ccgtaagtga aacgaagttt ttgtttttca gccaattgca aaccgtattc tgacaattta
    20101 gaacggttgt ttggtccgtg ttgtcctggt acgtagttac gacgtgccaa ttctttacct
    20161 gtacctgtaa gtgaaaggcc aaggcgacga gcttgtttcc aagatggtcc tgtataacgt
    20221 gacatatgaa tgtcctcctg atataaataa tatttcggtg gaaatagtca cttagaaagc
    20281 cctgattcgt gcagatgccc ttcgcctaaa cagccaaggt tacttgtcat aagacacctg
    20341 ttgacgagct tcatgctttc ctgctgatat ttcacacaaa atctattcta ccatgaatag
    20401 ctggatttgt aaaggggttt taggctttat tttcactacc agagaggttg agaacgaggg
    20461 taaaggtact tcctagaccg tactggctgc tgactgtgat ttccccaccc aattgatggg
    20521 ccaattcacg cgcaatcgca agtcctaatc catgaccacc tgtcttcatg ttacgcgaag
    20581 tttcgacacg ataaagacgt ttgaaaatat tttccaaatc ctctggggca ataccctgcc
    20641 cttcatcggt cacactgatt gaaagctggt ccttctccag cttagccacc acttccagct
    20701 tggttcctgg agcagaatat ttaaaagcgt tatcgaccag attcaccaag atacgagaaa
    20761 gcttagcata atctccctca atccgggcag actctgggat tacctgcaag tggacatctc
    20821 ttctctcctg ctcaatcaaa aactgaaatt cactcatgca ctcaattaag agcttgtcca
    20881 gaaaaatact gtctttactg gtagtttcca cctgattcct agctgtgttt agggtcaaaa
    20941 aattcaactc ctcaaccagt ttattgagcc tctccgtctg gcgtccaatg gttgctagat
    21001 aatgagcttg ctccgactcc ttgataatcc catccaaaat cccttctacc gtcgcttgga
    21061 tcgaagtgat aggagtctta atatcatgcg acaactgggc aatcatcaag cccttttctc
    21121 gttcgctttc ttccaaggaa tcaaagctta cctgcaaatc atgggacatc tcattaaaag
    21181 tttgccctaa ttgctgaaat tctacaggac cttgaacctc caaatttgaa ggaaaatcct
    21241 tggccgctac ccgcttggca tgctccttga gtttgcccaa cgacgtaaag actggcaata
    21301 ggagaaagag actaatccca gcaccgacaa ggctggcaac gatggtcatc ccaagcaaaa
    21361 agtaaatctc gcctttcgca atcagcattt tttgaacagc ccaaaaaaca accaaaatgg
    21421 ttaagagggt tgaaataata tatccaacca aaatataact ttttagtttc atgtttgtcc
    21481 tctcggtttc tctatcttat atcccaaccc ccaaactgtc ttaatagtgg gcgtttggtc
    21541 actactatat tttgccagct cctgtcgaag agcatggata tgcacattca aggtattggt
    21601 gtcatccacg tagtcttctt tccagatctt ttcatagagg tctgtcttgg agaaaactcg
    21661 ctctggattg ctagctaaaa tccacagcaa ttcaaatgat ttaacagtta aatccagcat
    21721 ttcttctcct atttgaactt catgactact atgattcatt tttagattgc caagggaaat
    21781 cagctctgtt tcgcccccac gatgaaggcg gcgcaaaata ttgtggacac gcaaaaccag
    21841 ctcacgtggg ctaaaaggct tagcaataaa atcatctgct cccaagctca ggccgtaaat
    21901 cttgtcctgt tcactggtct tagcagtaat aaataggaaa ggctgctctg gtgataagta
    21961 ttgaacctca ctgattaaat cataaccatc catccgaggc atcatgacat ctgtgataat
    22021 caaatcaatc ggttttttct tgaacagctc tagcgcttcc agtccatcat gggctaccaa
    22081 gacctgataa cctgcctgaa ttaagtatct ctgatgaata tctgtgattt ctacctcgtc
    22141 gtcaacgagt aaaattgtct ttcccatctg tctctccttt gataaaaaca gtgctatact
    22201 gctttaagta taacactatt tttattgttt tacgatgatt ttaatctgct attgaaagaa
    22261 agtcctgatt gctgattgag ttgttaaact aatcttagtc agcccactat ccatcattta
    22321 tttccttagc tgattagttt tcttcttttt tgtttttcaa acctagacca ccgagtaaac
    22381 ctgcaagcgc aagcccaagg aaaccaatac ttgccattga tgtttgagtc tcaccagtat
    22441 ttggtagcat agctttatcc tctgacatca tcgtatcaga catcttgtta gcagaagcag
    22501 ccatgttttc acctgccatc gtgttggtag aacttgtcat ggtgtcagca ggcatgctat
    22561 ctgtagtacc tgtagcatga ttgtgattca tcggagtcac gccagaacca gagttagaag
    22621 gtgataatga accatttgct gtgtctgatg tttctttaac atttatctta atagtgactt
    22681 ttttagttgc tacgatgttg tccaa
//
LOCUS       DAVMJI010000033        21772 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.033, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000033 DAVMJI010000000
VERSION     DAVMJI010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21772
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.033"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(<1..193)
                     /gene="blpI"
                     /locus_tag="VYR58_001588"
     CDS             complement(<1..193)
                     /gene="blpI"
                     /locus_tag="VYR58_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV3622716.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSS"
     gene            475..1062
                     /locus_tag="VYR58_001589"
     CDS             475..1062
                     /locus_tag="VYR58_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV3622717.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            989..2632
                     /locus_tag="VYR58_001590"
     CDS             989..2632
                     /locus_tag="VYR58_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV3622718.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLVQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2643..4004
                     /locus_tag="VYR58_001591"
     CDS             2643..4004
                     /locus_tag="VYR58_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV3622719.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            4061..4189
                     /gene="blpC"
                     /locus_tag="VYR58_001592"
     CDS             4061..4189
                     /gene="blpC"
                     /locus_tag="VYR58_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV3622720.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(4260..5600)
                     /locus_tag="VYR58_001593"
     CDS             complement(4260..5600)
                     /locus_tag="VYR58_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV3622721.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(5614..6351)
                     /locus_tag="VYR58_001594"
     CDS             complement(5614..6351)
                     /locus_tag="VYR58_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3622722.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(6356..6694)
                     /locus_tag="VYR58_001595"
     CDS             complement(6356..6694)
                     /locus_tag="VYR58_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3622723.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            6970..7299
                     /locus_tag="VYR58_001596"
     CDS             6970..7299
                     /locus_tag="VYR58_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV3622724.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7467..8516)
                     /locus_tag="VYR58_001597"
     CDS             complement(7467..8516)
                     /locus_tag="VYR58_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622725.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8513..9244)
                     /locus_tag="VYR58_001598"
     CDS             complement(8513..9244)
                     /locus_tag="VYR58_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622726.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVADPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9312..9722
                     /locus_tag="VYR58_001599"
     CDS             9312..9722
                     /locus_tag="VYR58_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV3622727.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9732..10019
                     /locus_tag="VYR58_001600"
     CDS             9732..10019
                     /locus_tag="VYR58_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622728.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10181..10375
                     /locus_tag="VYR58_001601"
     CDS             10181..10375
                     /locus_tag="VYR58_001601"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622729.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSNHTHD
                     KPTLTWFEEIFEEYHSPFHN"
     gene            complement(10709..11845)
                     /gene="dnaJ"
                     /locus_tag="VYR58_001602"
     CDS             complement(10709..11845)
                     /gene="dnaJ"
                     /locus_tag="VYR58_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV3622730.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12247..12603)
                     /locus_tag="VYR58_001603"
     CDS             complement(12247..12603)
                     /locus_tag="VYR58_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV3622731.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12605..14428)
                     /gene="dnaK"
                     /locus_tag="VYR58_001604"
     CDS             complement(12605..14428)
                     /gene="dnaK"
                     /locus_tag="VYR58_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV3622732.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14908..15432)
                     /gene="grpE"
                     /locus_tag="VYR58_001605"
     CDS             complement(14908..15432)
                     /gene="grpE"
                     /locus_tag="VYR58_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV3622733.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15459..16493)
                     /gene="hrcA"
                     /locus_tag="VYR58_001606"
     CDS             complement(15459..16493)
                     /gene="hrcA"
                     /locus_tag="VYR58_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV3622734.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16657..17166)
                     /locus_tag="VYR58_001607"
     CDS             complement(16657..17166)
                     /locus_tag="VYR58_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV3622735.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            17774..20107
                     /locus_tag="VYR58_001608"
     CDS             17774..20107
                     /locus_tag="VYR58_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV3622736.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMNTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTIAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20120..21583
                     /locus_tag="VYR58_001609"
     CDS             20120..21583
                     /locus_tag="VYR58_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV3622737.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21583..>21772
                     /locus_tag="VYR58_001610"
     CDS             21583..>21772
                     /locus_tag="VYR58_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HEV3622738.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         6905 a         4441 c         4014 g         6412 t
ORIGIN      
        1 aagaggacat aattcctgaa cctacacaaa taagtgttgc tgctccccca gttatcggac
       61 cagtcgcagc agctaatagt actgctccaa tacaaccacc gattgcagat cctaaattgc
      121 ctcttcctcc actaactatt tcgagttctt cattatccat aacagaaaat tgttccatca
      181 tttttgtatt catgacaaat actccttttt tcttttttta tttttgtctt gttgtaactt
      241 tgataagttt agtatatcat cgttttttaa aatttttcat ccagatcttg aattgtcatc
      301 gaaacgtctt gaattaggtt ttttatttca agccacctct aaatgtttaa aaaaaataat
      361 ttctaatcac ttttttacca ttcaggaagt tttaatgact attcaagatt tcataaaata
      421 tgaacttagt tttatgacat aatagaccta tccactatat gaaaggaatt gccaatgact
      481 tcttataaac gtacatttgt tcctcaaata gatgcgagag actgtggtgt cgctgcctta
      541 gcctcgattg ctaaattcta tggttcagat ttttctctag ctcacttgag agaacttgca
      601 aagaccaata aagaagggac gactgctctt ggcattgtaa aagccgctga tgaaatgggc
      661 tttgaaacaa gacctgttca agcagataaa acgctctttg acatgagtga tgtcccctat
      721 ccatttatcg ttcacgttaa caaagaagga aaactccaac attactatgt tgtctatcaa
      781 acaaagaaag actatctgat tattggtgat cctgaccctt ctgtaaaaat cactaaaatg
      841 tcaaaagaac gctttttcta tgaatggact ggagtagcta tttttctagc taccaaaccc
      901 agctatcaac cccataaaga taaaaagaat ggtctactaa gcaagcttcc ttcctctgat
      961 tttcaaacaa aaatctctca ttgcttacat tgttctctca agcttattgg tcactattat
     1021 caatataggt ggttcttact atctccaagg aatcttggat gaatacattc caaatcagat
     1081 gaaatcaact ttaggaatca tctcagttgg tctggttatc acctatatcc tccaacaagt
     1141 catgagcttc tccagagatt atctcctaac cgttctgagt cagagattaa gtattgatgt
     1201 gattttatcc tatattcgcc atatttttga acttcccatg tctttctttg cgacacgtcg
     1261 tacaggagaa atcatttcac gattcacaga tgctaactct attatagatg ccttggcttc
     1321 taccattctt tctctttttc tggatgtttc tattctgatt cttgtaggag gcgtcttact
     1381 ggtacaaaac cctaatctct tccttctttc tcttatttcc attcctatat acatgttcat
     1441 catcttttct tttatgaaac ctttcgaaaa aatgaaccat gatgtcatgc aaagtaattc
     1501 tatggttagc tctgccatta tcgaagatat caacgggatt gaaactataa agtcgctcac
     1561 gagtgaagaa aatcgctatc aaaatataga cagcgaattt gtagattatt tggaaaaatc
     1621 ctttaagctc agtaaatatt ctattttaca aacgagttta aagcagggaa caaaattagt
     1681 tctgaatatc cttatcctat ggtttggcgc tcaattagtc atgtcgagta aaatttctat
     1741 cggtcagctg attaccttta acacactttt ttcttacttt acaactccta tggaaaatat
     1801 tatcaacctc caaaccaaac tccaatctgc gaaggtcgct aataaccgtt tgaacgaagt
     1861 ctatctagtc gaatctgaat ttcaagttca agaaaaccct gtccattcac attttttgat
     1921 gggcgatatt gaatttgatg acctttctta taagtatggt tttggacgag ataccttaac
     1981 agatattaat ctcacgatta aacaaggaga taaggttagc ctagttggag ttagtggttc
     2041 tggtaaaaca actttagcca aaatgattgt caatttcttt gaaccctaca aaggacatat
     2101 ttctatcaat catcaggata ttaaaaacat tgataaaaaa gtcttgcgcc gtcatattaa
     2161 ttacctacca caacaagcct atatctttaa tggctctatc ttggaaaact taactttggg
     2221 cggtaatcat atgattagcc aagaagatat tctaagagct tgtgaattag ctgaaattcg
     2281 tcaagacatt gaaagaatgc ctatgggcta tcaaactcag ctctctgatg gagctggtct
     2341 atcaggagga caaaagcaac gaatagccct cgctcgtgct cttttaacta aagctcctgt
     2401 tttaatacta gacgaagcta ctagcggtct tgatgtcttg actgagaaaa aggttataga
     2461 taatcttatg tctctaactg ataaaaccat tctctttgta gcccatcgtc tcagtatagc
     2521 cgaacgaacc aaccgtgtca ttgttcttga ccaggggaaa atcattgaag ttggtagtca
     2581 ccaagagtta atgcaggcgc aaggtttcta ccatcatcta ttcaataaat aaggagaatg
     2641 tcatgaatcc taatcttttt agaagcgtcg agttttatca gagacgttac cataactatg
     2701 cgacagtgtt cattatacct ctttcattac tatttacttt catcttgatt ttctcccttg
     2761 ttgccacaaa agaaattact gttacttccc aaggagaaat cgcccctaca agtgtcattg
     2821 cctccattca gtcaaccagt gataatccta tcctagctaa tcatttagtg gcaaatcaag
     2881 tagttgaaaa aggggactta ctcatcaaat actctgaaac aatggaagaa agtcagaaaa
     2941 ctgccttagc aactcaatta caaagacttg agaagcaaaa agaaggactt ggaattttga
     3001 aacaaagctt agaaaaagcg actgatcttt tttctggcga ggatgaattt ggctaccata
     3061 atacctttat gaattttact aaacaatccc atgatattga actgggtatc acaaagacta
     3121 acaccgaagt ttcaaatcaa gctaatcttt ccaatagcag ttcatcagct attgaacaag
     3181 aaattacaaa agttcaacaa caaattggag aatatcaaga gttgagagat gctatcataa
     3241 ataacagagc acgcttacca actggcaatc cgcaccagtc aattttgaat cgttatcttg
     3301 tagcctcaca aggacaaaca caaggaactg cagaggagcc atttttatct caaattaatc
     3361 aaagtattgc aggtcttgaa tcatctatcg caagcctcaa aattcagcaa gctggtatcg
     3421 gaagtgtagc aacttatgat aacagtttag caaccaaaat tgaagtactc cgcactcagt
     3481 ttttacagac agcctcacag caacaactaa ctgtggagaa tcaattaaca gaattaaaag
     3541 tacaactaga tcaagccaca cagcgtttgg aaaacaatac cttaacctcc ccaagtaaag
     3601 gtatcgttca tctgaacagc gaatttgaag gtaaaaatag aattccaact ggtacagaaa
     3661 ttgctcaaat attccctgtc atcacagata caagagaagt actaatcact tactacgtat
     3721 cttctgacta tctacctcta ctagataaag gacaaactgt aagattaaaa ctggagaaga
     3781 ttggaaatca cggcaccacc atcatcggcc aacttcagac aattgatcaa actcctacca
     3841 gaacagagca aggaaatctc tttaaattaa ccgctcttgc aaaactatct aacgaggata
     3901 gtaaactcat ccaatatggc ttacaaggtc gcgtcactag tgtaactaca aagaaaacat
     3961 attttgatta tttcaaagat aaaattttaa cccattctga ttaattttca gataacactc
     4021 tataactatt tattatctta tcaaaaagga gaatcataac atggataaga aacaaaacct
     4081 aacttcattt caagaactaa caactaccga actcaaccaa attacaggtg gaggattgtg
     4141 ggaagattta ttatataaca ttaatagata tgctcattac atcacataag aacttcatca
     4201 tccaatacaa ctataaaaaa ataagaccga gaaacaagta ctctcggtct tatttttcat
     4261 cattctgtat gtatcacagt aagtacctga cgaaagactt gattttgaca ggtggtattt
     4321 agactggtat taggatggct ttccacaatc ttcatgacgg tatagagacc aactcctctc
     4381 tcctcccctt tagaactggc tccaaaggag aagatttcag aaatatcgat gccctcttct
     4441 ttgatggagt tttcgatgat aaaggtctcc tgtgctccat tttttaaaaa ggcgattgaa
     4501 acatgaggtt gactagcttc cacactggct tcaatagcat tgtcacaaag gatagacaca
     4561 atggttagaa aatcaagtag actcatcccc tcgacctgaa tctcctcagg aacttcgaca
     4621 ttaaagacaa tgttcttatc tctggctttt aaaaatttcc ctgctagaag acttttgagg
     4681 gctttatcac gaatatttac caatctgccc aggtcatatt tattgttctg caatttctga
     4741 ctggaatcct ttaagacgga gccatagacc tcttttatct gctccatatc ctcctcttca
     4801 atgcccagac gtaagctagt caagaggttg gtataatcat gacgaaagct ccgtacttcc
     4861 ttgtaaagct cctctatatg ccgactatag cgttccatat ctctatagcg cagggcctgc
     4921 tcttgttcca atctctcata gagtttttcc ttcaaatagg tatccaattt cttgataacc
     4981 cccataaaaa agagtaggta aaagactagg atgagatggc gaacagtctt tgattgaata
     5041 ctttgttcat attcaaaaaa agacagactt tccatgacta gatagtagcc acccattatc
     5101 cagttaatct gagtcaggga cttttgaaag gctttatcga gaatctcctt tctcaagcta
     5161 gtaaaatcgt agtccaacca tttcaaaaaa gctagagaaa tgaagaaatt gaaaattatt
     5221 atacataacc cagtaaatga gtagccatca tatacttgcc cttgtcccaa aaatggaagc
     5281 acaaaatagg agactcctct ataaaagaga ttcaccaata tcattggaaa gagaccataa
     5341 aagaaaagga gttttttagg aagccctctc aataataaga aagataagcc tatgccgtac
     5401 aagggttcca taaaataaga taggtaaaca tttcctacta tatagctaat catcacaaaa
     5461 acaaaggcca acagtatctt aaaaagaaag gccttaaaaa tcctctcgaa agtaagatca
     5521 attccatcca ccttaaagaa gatgacaatt tctagtccat tagtaacaag tgtatacaac
     5581 aatatccaag caatgttcat aaattctcct agctcagtgt aatttattga tggcctcaga
     5641 cacttccctg accttataac gggcgattag acaacttcca ccattgggaa agaaaagcag
     5701 tttttctttc ttatccaaat gcaccacatt tgcaggattg atgagaaaag agcggtggca
     5761 ctgcaagaga cggggctcct gcttgaaaac ctcctctaaa ctcgctgtaa attccagcct
     5821 gtctgtcttg gtatagagaa taacacgatg ggctctgggc gacgtttcga gatagtaaac
     5881 ctctttaaaa ggatactgaa attgggcaaa ttttgattta aagtaaaagc aatcttccgc
     5941 cagactttta ctatcttgac tattggcata gaggagggct gtctcgatcc gagattcaaa
     6001 ctcctctgct gacaaggcct tatcaatgta gtccaaagca gacacttggt agcgaaaaga
     6061 caggggcata aactccgagt gagtcgtcac aaagacaatc agggcataag gatcccgatc
     6121 ccgaatcttt ctagccactt ccagtccctt catctcttca tttcgaatct caatatccaa
     6181 aaagaatagc tgatgggccc ccttctcatg cacttcagcc agcagttggt ccggcttgcc
     6241 aaatacctca aaagagctag gaatgatatg atgtgctttc aaaagtttct caatcgtcgt
     6301 ttcaattcta gtctgttggg aaaaatcatc ctctaaaaca aatattctca tcttcttact
     6361 ctccctcttt caaccatttt tgacgaattt ctctatagcg acgtctggca tacttgacag
     6421 cgtattgacc ttcttctccg agaaaaagga ttctttcttg aaaatcaatc gattttaatt
     6481 tatcaagatt aaccaaacaa tttcgatgac atctcatcaa ggtttcccca cattggttct
     6541 caagattact taaattttga agcatattaa aactagcttc ttctgtaaca atctgtacgg
     6601 tatgggcttt agttggatgt gtttggatat agtagatatc gtcgatgttt actttataga
     6661 ctgttttctg cgtctgaata atcatatatt tcattggatt ctcctcctaa gaaaagaata
     6721 acagaaaagg tctagcccaa gcacacccaa tcctaaacag tctttgaaaa ctcctaaaag
     6781 gattattttc tacaacatca tgatgagctt acaactattt tatcataaaa ttcactcagc
     6841 gcaattcaag acatttcaat gacaattaaa gatttgaata aaaaaaaaga attaaaagtg
     6901 ataaactaac agtatcaaaa cacagttgcc agaagtaaga ctggcaccca gattaaagga
     6961 ggcattccca tgacagatac agaccccatc aaaagagctc atactttgat tactgactta
     7021 aacaaagcct accaagcatg caaacaggca agcgctgacg acgtccgctt tcaggagcaa
     7081 ttaaactcta ttcttggttt tctagccaag gctgaaacag tggataatcg attcttgatt
     7141 gaactagaaa aattttacca gacttccagt cttctcatgg gactcagcgc tcttgatcca
     7201 gatgctccaa ctcgcgccgc ttggcgggcc tatgaccgct tccactttga ccaagtcaag
     7261 accaagttaa tactcaatga aaatcaaaga gcaaactagg aagctagccg caagctgtac
     7321 ttgagtacgg taagacgacg ctgacgtggt ttgaagagat tttcgaagag tataagtctc
     7381 tacggaccaa ccattatcct gtagtaacaa aaaagaagtt gagacagact gaactcaact
     7441 tcttttttag tgtcgtatca gcaatgttag tcctgcatct gacgttttac ctgataaggc
     7501 aaatacaaga ctagtaaaac caaaccagct cctagtaagg ctagaagggc tagtttttct
     7561 tggaaggtaa tcaacccaac aactaattcc acaagtaaaa caaaactggt caatcctcga
     7621 actacctcct gtaagccttt ttccttttgc cccttgtcca gcggaaagag ttgggtcaaa
     7681 tactggtagt caaaggcatg atagagggcc agcaactgga agagcaagag gtagttaaag
     7741 agaactacca ctgctgtcgc aatccaagct tgctcgataa aaacctgcgc cagtacggaa
     7801 agtaagagaa gacgaagact aagagcaaag aggtcgccat ttcgcagata agaacgcaga
     7861 tagagatttt gccaaatctt cccaggcacc ttctgaacag cctttaagat aaagtccaga
     7921 taggcacgac gcttaacgct gtttgaaatt cccttgacct gcgtaaagag ggcaaagaaa
     7981 cgaagcaaga cttgcttacg cttgctttct tgggaaatga catagtccca atccagtcca
     8041 gtttcagtga aaaatttgct ggccttttga cgaaagtgga aatattttcc tacccccaat
     8101 aaaagcacat agagcagaaa aactggcaag ccataaccca ttgctaaaaa taaaggcgca
     8161 aataacagca agaaaagggt ctgtacaaag agccaaaaga ctagggaaat gccagtttga
     8221 cgcttgagat ggagcttgat ttcctcttct ccaactaaga gaaagagctt gtctggagcc
     8281 tccatatagg tggcaattcc tccccaaagt aaaagtaaaa cagacgtaat tcctacaaac
     8341 aaaaggatag gccaatgatt ttcaggaaaa tgttgtaaga gttgactgta ctggtaggct
     8401 agaaagccca acaggacaag caggaacaag acaaagtggt cattgagcac atagcgcaga
     8461 taaccaagac actccttacg aaaggcctgc tttctcttta aaaacaagtc tttcataggt
     8521 cctcctcttt tgtcagagcc aagtaaatat cattcaaact agcctcaggc atatcaaagg
     8581 cttcgcgtag ttgcaggaga ttgcctttgg cacgcacctc tcccttgtga agaatgacaa
     8641 aggcatcaca catcttctcc gccgaatcca gcacgtgggt actcatgaga atagacttgc
     8701 ccttttgctt ctccacttcc aaaagctgaa tcaaatcaga aatagccagc ggatcaagac
     8761 caaggaaagg ctcatccacg atgaaaagac ttggatccgc cacaaaagca cagataatca
     8821 tgaccttctg cttcatccct tttgaaaaat gaacagggaa ccagtctaat ttctgttcca
     8881 aacggaacat ttttaacaag ggctctactc gttcgaaagc cactttttgc tcaataccgt
     8941 aagccatagc aaccgtttcg atatgctctc tgagggtcaa ttcctcatac agactaggcg
     9001 tctcaggaat gtagccaatc tgcttgcggt agctagtcgc atctccttgc agagtcaggc
     9061 cattgatatt gatggagcca ctataaggtg ccaacagacc gataatctca ttgatcgtcg
     9121 ttgatttccc agcaccattg agaccaatca aaccgaccaa ctgcccactt tcaacagtaa
     9181 aggacacatc tttcaaaaca ggaacatgaa catagccacc tgtcaggttt ttaatttcta
     9241 acatattttc tccaaatctg gtataatgta gctatattat atcaaaattc agtacagtag
     9301 aggtagattt tatgtcagat tgcatttttt gtaaaatcat cgcaggggaa attcctgctt
     9361 caaaagtata tgaagatgag caggtccttg cctttcttga tatctctcaa gtaacactag
     9421 gacacacctt ggtcgtgcca aaagaacact atcgcaatct tttggagatg gatgctacga
     9481 gcgccagcca actctttgcc caagtaccaa aagtagctca aaaagtcatg aaagtcacta
     9541 aggctgctgg tatgaatatc atttccaact gtgaagaagt cgctggtcaa acagtttttc
     9601 atactcacgt tcaccttgta cctcgctaca gtgctgacga tgacctcaag attgatttta
     9661 tcgcccacga accagacttt gacaaacttg ctcaagtcgc tgaaaccatc aaaaacgctt
     9721 aaggagttgc tatgaaatta tccaacctac tgctatttgc aggagctgca gccggaagtt
     9781 atctggtcac aaaaaatcgc caaaccatca cagatgaagt cttgaatacc actgaccgcg
     9841 ttcaagctat caaggacgat gtggatatta tccaaaacag cctgcaaatc attgaccagc
     9901 aaaaagaact tatcaaggaa taccaagaag acttgactta caagtttaag gtcttggaaa
     9961 aggatatcca gactagacta gctgtgataa aagaaatgca gggaactgaa gataagtaaa
    10021 aagagcccga cggctctttt ttaaaacgta aacaagttat agtgaattga atttagaata
    10081 gcacatcata gtttctaaag cattgttaga gattacttta aaatcctctt atcaatttgt
    10141 tcatattcta tttcaatcta ctatatatat cccatcaact atgcatcata atttaggtaa
    10201 ctcatactca ataaaaatca aaaagcaaac tagaaagcta ggcacagact gctcaaaaca
    10261 ccgttttaag gttgtggata gaactgacga agtcagtaac catacccatg acaagccgac
    10321 gctgacgtgg tttgaagaaa tttttgaaga gtatcattca ccatttcaca actaaatcga
    10381 agactttctg ccgtaatgaa aacacctgaa acagcttggt ttcggctatc cggaaacttt
    10441 aagacttagg ttcaaagttt aggtatggaa cttcgaagga ggtcgctacc gtccgtcatt
    10501 acttaggaaa gtcttaaaaa atctataaag taaaaagagc ccgacagctc tttttgttta
    10561 tactcaatga aaatcaaaaa gcaaactagg aaactagcca cgggctgctc aaaacactgt
    10621 tttgaggttg tagatacgac tgacgaagtc agtcacatat atacggcaag gcaacgctga
    10681 cgtggtttga agagattttc gaagagtatt attctccatc aaaggcatct ttaatatggt
    10741 caaagaagcc ttttttcttt ggatttactt tcaagtcacc agcagccgcg aattctttca
    10801 aggctacttt ttggcggtcg ttcaagcctg tcggtgttac gacattaaca gtaacgtatt
    10861 ggtcaccaac tgcaccgcca cgaaggctcg gtgccccctt actacgtagg cggaacttct
    10921 taccagtctg agttccctct ggaataacca attcaacatc accgtgaaca gttggaatat
    10981 ctactgtatc accaagagcc gcttggacaa agttgaggtt gagattgtag aagatagtcg
    11041 ttccttcacg ttcaaacttg tcgctagctt ccacagaaac tactacatac aagtcaccat
    11101 aaggtccacc gttaaagcct gcttcacctt gaccagcgag gcgaatttgt tgacctgttt
    11161 ccacaccagc agggattttc acatgtacgc tatgagcttg tttctcatga cctgttccat
    11221 gacaggttgt acatggatat ttgatttctt ttcctcgacc gtgacagaca tcacaggtta
    11281 cttggcgacg catcatacca agaggagtct gcgtatcgac gttaatgaca ccagcgccat
    11341 gacagcgtcc acaagtgact ggacttgtcc ctggcttagc accagatcca ttacatgtac
    11401 gacagccagc ttcacgatga tacttaactt ccttctcagt tccgaagata gcttcttcaa
    11461 aggtcaaatt gacacgatac tggagatcat ctccttggcg aggagcgttt ggattgcgcg
    11521 aagaaccgcc tccgccgaag aaacttgaga aaatatcctc aaaaccaccg aagccacctg
    11581 ccccattgaa accgccgaaa ccaccagctc caccaaaacc accattggcg cctgcagcac
    11641 catactggtc ataggcagca cgtttttggt cgtcactcaa agtctcatag gcttcttgaa
    11701 cttccttgta cttgtcctca gcaccaggct ccttgttgat atctgggtga tattttttgg
    11761 aaagcttacg ataagccttt ttgatttcgt ctgccgaagc gtttttggat acccccagac
    11821 gatcataaaa ttcagtattg ttcataattc aagatacaaa gggcgtcaaa cggacacagc
    11881 catctaggag ttttgacgac ggacgcttac gtcctagaaa aaactatctt tttggcacag
    11941 tccatagccc gtgttcagtt acgaacaccc ttattccttt ctattgatgt tctgaatcga
    12001 accaccattt aggtcgggtt caattccttt cttttatatt tagtaagaaa ttctgaaacc
    12061 cgtgttcagt tacgaacact ctttgttcct ttctattgat gagacaaaac ccaaacaaat
    12121 gagattccgt ccctttttat cgaaaaacag aggctgggtt gcaacctctg caaataagta
    12181 aattaacttt attttgattt taaatatcct ataagtacag aaatatttat atatttttgt
    12241 ctcttcttag tatttgccta tataattcca attgatcata agaaatacaa ctactgtcca
    12301 aatcatacca attatgaacg gtattacaaa tttatatgtt tgtatttcta atgatatcat
    12361 agctgatacc atcgctgata caaatgcaga caacaatact gaagtaacaa aattccttac
    12421 cgcttcatca tttttgacac aactatcatg ctcagctaat ataatttctc tatatatagt
    12481 caaacattct actggaatat tatctataaa accttttgct gcttcatagt tgtcagcttg
    12541 attacaaaaa tcattataaa cttttcgtgt attttttaga tactcatcat ccaatacact
    12601 catcttattt ttccgtaaac tctccgtcta cgacgtcatc gcctgcgttt cctgttgctt
    12661 gtgcgccttc tgctccttct tgagcttgtt gcgctgctgc ggcttgttcg tagagtttca
    12721 cagcaaggcc ttgagctttt tcgttcaacg cttcaagttt cgctttcatg tcgtccaagt
    12781 tgttgtcttc ttgagctttc ttaaggtcat caagggcagc ttgggcagcg tcacgttctg
    12841 cgtcgaagcc tttaccttca gtttccttga ttgtcttttc agtcgcaaag attgcttggt
    12901 ctacttcatt acgaaggtct acttcttctt tacgtttctt atcggcttca gcgtttgctt
    12961 ctgcatcttt catcatgcgg tcgatttctt cgtcagtcaa acctgagttc gattggatga
    13021 caatagtttg ttctttttga gttccaaggt ctttggcctt aacagacacg ataccgttct
    13081 tgtcgatgtc aaatgttact tcgatttgag gaattccacg aggtgcagct gggatatcag
    13141 tcaattggaa gcgtccaaga gtcttgttat ctgctgccat tgggcgttca ccttgaagaa
    13201 cgtggatatc aacggctggt tggttgtctg ctgctgttga gaagacttgt gatttagatg
    13261 ttgggattgt agtgttgcga tcgataagtt ttgtaaatac tccacccatt gtttcgatac
    13321 caagtgacaa tggcgttaca tcaagaagga caacgtcctt gacatcacca gtaatcacac
    13381 caccttggat agccgcaccc atagcaacta cttcatcagg gtttactgat ttgtttggtt
    13441 ctttaccagt ttcagcttta acagcttcaa caacggcagg gatacgagtt gaaccaccaa
    13501 caaggataac ttcgtcgatt tctgacaagc tcaaacctgc atctgaaagg gcttgacgaa
    13561 ctggaacttt tgtacgttca acaaggtcac gagtcaaatc gtcaaatttc gcacgagtca
    13621 aagtcatttc caagtgaaga ggtccagcct cacctgcagt gataaatggc aagctgattt
    13681 gtgttgaagt tacaccagaa aggtctttct tcgctttttc agccgcatct ttcaaacgtt
    13741 gcattgccat cttgtcagta gacaagtcga taccgttttc tttcttgaat tctgctacca
    13801 agtggtcaat gattttttgg tcaaagtcgt caccaccaag tttgttgtcc cctgcagttg
    13861 acaatacgtc gaagacaccg tcacccaatt caaggataga gacgtcgaat gtaccaccac
    13921 caaggtcaaa taccaagatt ttttcttctt tatcagtctt gtccaaacca taagcaagag
    13981 ctgctgcagt tggttcgtta acaatacgtt ctacttcaag accagcaatt ttaccagcgt
    14041 cttttgttgc ttgacgttga gcgtcgttga agtaagccgg aactgtgata acagctttgg
    14101 ttactttctc accaaggtag tcttcagcgt agcctttcaa gtattgaagg atcatagctg
    14161 agatttcttg tggagtgtat tcttttccat ttgcagaaac tttttcagaa gttcccatct
    14221 tagatttgat agagataact gtatctgggt ttgtgactgc ttgacgtttt gcagcatcac
    14281 caacgatgat ttctccgttt ttgaatgaga ctacagatgg agttgtgcgg tttccttctg
    14341 ggtttgcgat gattttgctt tcagttcctt caagaactgc aactgctgag tttgttgtac
    14401 ctaagtcaat accgataatt ttagacatgt gtttttctcc ttgttagtta attttctatt
    14461 tttctttttg atactcttct taagtggcga cgccgtcaga gcttgacttc gtcaatctct
    14521 ttgactaaac tttgagccta aggtctcaaa atttgcgcaa atagcgccac ggcgaagagt
    14581 atcgtgtttg gttcgcttcg ctcactatta caaagccaaa catattttat ctttcttcat
    14641 agtttattgt cgtttcggac aagttttcta ttatgtaaat tgcgacacga agagtcgaaa
    14701 tcgattttat ttcgacgacg agttagtaag gaagctaggc aaacgccata gcgattgccg
    14761 ttttctgacg agttgcttta gctaccgtca gaattgccga atcgaacacg ccctaagctc
    14821 tgagtaaaaa agatagattt tcttgtgttc atcgaacact tcgttaatct cctattttta
    14881 ctgcgagctt tttacgggct ttgtatctta gttatacacc actaccattg ctgggcgtag
    14941 gatgcggtca tggagtttgt agcctttttg aaagacttga gcgatggtat ctactgggtg
    15001 ttcatcgtct gctgggagag tttggatggc catatggtag ttatggtcaa attcgccatc
    15061 tgctgcgatt tcttcaattc cttcttcttt caaagcgtga atcaagcttt cttgcaccat
    15121 ccccaagccc ttcttcacat catctgtcaa accttcaact gcaagtgcac gctcaaggtt
    15181 gtcaagagat ggtaagattg cttttgccaa gtcctggcta cgataacgtt gcaagttttg
    15241 acgttcttca ttggcacggc gttggatatt ttgcatttct gcatgagcgc gaagatattt
    15301 gttttcgaac tcatctgcac gttcatttgc caagtccaac tcagactttt caggagttgt
    15361 ttcttcagct gtttccacaa cttcctcttc ttgaacttct tctacttctt cattttttat
    15421 atcttgggcc atgttcgcct cctttaatga tttcaatctt aatgtacttc gtaatgatta
    15481 ctgctgaggt agcggtaaaa atctgtcaac ttcatggtca aaacacggtt gaccacattg
    15541 atttgattga ttagctgttg gtaatccaga ttaactggac cgataatggc tagaattcca
    15601 actccccgat aaggaatgag gaacttacta ctaatcaccg ctaggtcagc taaacaggac
    15661 tcttgaccgt ctgcaatacg aacattttgc atctgatcct cacgcaaccc ctcacgaatc
    15721 tccaaggcca ccttttgcgg ttggtcaaag aactgatagg ctgctagatt ggcaaaattc
    15781 aagagattga ccttgcccgc catcacaatg ttttcgttga acatttcctt aaagatgtgt
    15841 tcaaagagat cgatgacatt atccgttgtt gtaaagtaac gctggataat ctgcggaatc
    15901 tccgtccgaa tcttgtagtg aatatctaaa acggtgtgac cgaggaaacg ttcctgaatg
    15961 atgctcttca gtttcagcaa atcctcctgc aagaagttcc ttggaatcag aaactgacta
    16021 gtaaccgttc gcgactcgtc tagggtaaat accgccaagg ctgtatgttg ccccaaaaca
    16081 acgatatcaa aggctgtcaa acgttgcctg ctcggctcaa catccagtgc cactaccgta
    16141 cagccactca ggtctgttag caagttagca gcctcttgca gaatatcctc caatttgaag
    16201 aattcctgat caaaggcttt gacaatctca tatacctcat tttcagccag ccggtgaaaa
    16261 tccagtgagt gtttcacata gtactgaaaa ccagcaacac ttggcatccg accgcttgaa
    16321 gtatgagcct tctcaagcaa cccttgtttt tctagttccg ccatgtcatt acgaatggtt
    16381 gcactgctag agttaataga ctcttgcaag gcttttgatc cgacaggttc gtgcgttttg
    16441 gtaaagatgt caataatcag atttaaaata tcctgctgac gctctgtaac catctcatca
    16501 ctcctctctg tctgatcaat tagcactcaa tgcatccaag tgctaactta tgattctatt
    16561 atacaccctt agaagagaat gtcaagacaa aaactcaaaa aattagcact cttttatcaa
    16621 gagtgctaaa aatcaatctg aagacctaga accttgctat tcatctactc ggtatttcct
    16681 ttttagtctg aaataaccat gaattagata agaaatcaga aaagcatata aaacaaaaat
    16741 aagaaagaaa gacatagaaa gatcctctct aaacaaactc gtacaaacaa caagaccacc
    16801 taagaaagta gttgtacagg aacgaagtct agatcgcata acttcccatt tgagcccctt
    16861 actcatatag acttgatcct ctggaagtaa atcagaagac gatttacgaa gaatcgaaca
    16921 agaacctgct cctatcaatt cccaacctct atctctaaaa tcttgcagtt catgcttata
    16981 ttttttaaga aatctagaat catagatacg gtagatgaca tcgtctggtt gacattggtc
    17041 aaaatagaac aaaccaaaac gactcgttct atacctccaa cctttcaaat gcatctcatg
    17101 taaatattct tcttccttgt ccaaatcaac aatggtgaaa atccgaaatt ctactctgct
    17161 attcattgtc ttaccccaaa attagaaaac atgcctggcg ttatttatta gataattctt
    17221 tccacttttg actcaatctc caaaaaatat aagaaatctg aatcgcaaaa actatcaata
    17281 aaacccaatc tattatgaaa atcaaaaaca ctttccaact gaaagaacta cctccagtga
    17341 caaactttga gcaaaacggt agtagagcta aaaagagaag taaaatagga agcatccgca
    17401 ttgttaaaat ccgtttggca taaaaaaatc tttatttaaa ctaaaatatt atagcaaaat
    17461 ttacgccagt ttttgaacgg ctgatgtaga tattttatac tttcaaaatg tttaaatgtg
    17521 attatttatt tttgaaaaat agctcaccag cccgactgaa agtgcttata gaatgataat
    17581 aagtcgcctg ccgaaaacag cggaaaatag cggtgttatg cggagataat ctgacgcgat
    17641 gcgaaagtat attgcatact tattttcaac aatttagcag agtattttta taagtgtgat
    17701 ataatagaag tataatttgt tctgatagtt tattttatgg agaagtagat ttttagaatg
    17761 cggagggttc aatatggttg agtttataaa gtctaagaaa gaaatgagtg aggaggatat
    17821 taaagcaaat ttcatcactc ctgctattgt atccaaagga tggaaaaatg gtgagcatat
    17881 cgcttacgaa gaatacttca ctgatggtcg aattgaggtt agaggagata aggctcgtcg
    17941 taaagaagga aaaaaatcag actattcact gtattaccaa tttggaactc gaattgcaat
    18001 tgttgaggca aaggataata aacacagcgt tcgagcagga ttacaacaag ctattgaata
    18061 tggagagatt ttagatgttc catttgttta ttcttcgaat ggtgatggct ttattgaaca
    18121 cgaccgtatc acgagagaag aacgtgagct ggagttagac gaattcccta ctcgtgaaga
    18181 attattttct cgtatgacga aggaaaaagg attgacgtac gaaattacag aagctatctc
    18241 aactccatac tatacagacg ccttctcaat gaacacgcca cgctattatc agcaaatagc
    18301 tatcaaccgt actattgaaa cagttgccag aggacaaaaa cgagtaatgt ttgtgatggc
    18361 aacaggaacg gggaaaacgt tcatggcttt tcaaattatt catcgccttc gaaaagctgg
    18421 tttggctaaa cgagttttat tcttagcaga tagaaacatc ttagtagacc aaacgatagc
    18481 tgaagacttt aagccattcg aaaaggtaat gacgaaaatt acaccaaaac ttttgactgc
    18541 tcctgaaaaa ttaaattctt ttgaaattta tctagggctt tatcagcaac taactggtga
    18601 agatggaact gaaacacatt atcaaaaatt tgacaaagac ttctttgatt taatcgtaat
    18661 tgatgaagcg caccgtggtt cagctaagga aaacagtaac tggcgtaaga taattgatta
    18721 tttcagttct gcgacacaga ttgggatgac cgctactcct aaagaaacca agaatgcttc
    18781 caatacggaa tactttggtg agccaatcta tacttatagt ttaaaacagg gaatcgagga
    18841 tggttttttg gctccatatc gtgttatgag agttaattta gatgtagatg tggatggtta
    18901 tcgtccagaa actggaaaag ttgatgctaa cggacaatta atagaagata ggtactacgg
    18961 caggaaagat tttgataaaa ccattgtcat tgatgataga acgcaaagag ttgccaagtt
    19021 tgtttctgat tatatgaagc aaaacaatgc acgatttgat aaaacaattg ttttttgtgt
    19081 tgatattgac catgccgagc gaatgcgtgc tgcacttgta aaagagaatc tagacttagt
    19141 ccaagaagac tatcgttatg tcatgcaagt aactggtgac aacgctgaag gaaaagctca
    19201 actggataac tttatggatg tcaattctaa ttttcccgct attgtaacaa cgtctaaatt
    19261 attaacgaca ggagttaatg ctaaaacatg tcgtttgatt gttttagact ctaatatcca
    19321 atccatgact gaatttaaac aaattattgg tcgtggcaca cgtctttatc ctcaaaaggg
    19381 gaaagaattt tttacgatta ttgattttcg aaatgttacc aatttgtttg ctgaccctga
    19441 ttttgatggt gatccagtga aggtgctgga aacaggtgcg aaaacagtca gtggttctac
    19501 gcccggtttc gtaagtgagg aaggtgaccc agtagaaaaa tatatcgtta cagacaagca
    19561 ggttaccatt cttaattcta ctgttcaagt attggatgaa aacgggaaac tgattaccga
    19621 aagcctgacc gactacactc ggaagaatat cttaggtagc tacgccactt tgaacgattt
    19681 tatcacagtt tggcatacgg cggataaaaa gaagcttatc ttagacgaac tttataaaaa
    19741 aggagtttat ctagatgcta ttcgagagtc ggagggaata tcagaacaag aaatcgatga
    19801 ttttgattta ctcctaaaac ttgcctatgg tcaaaaagaa ttaaccaaaa cggaacgtat
    19861 caataagctc aaacaaagcg gatatttata taaatatagt gaggaagcgc gtgctgtttt
    19921 ggaaatttta ctgaacaaat acatggataa aggtattgga gaactcgaaa gcattgaaac
    19981 attaaaactt ccagaatttc agatatatgg tggaaccttc aaaatcatca atacttattt
    20041 tggagataaa aaacgatatt tacaagcaat taaagaattg gagcaagagc tatttacagt
    20101 agcttaatga aaggaaagta tgtcaattac atcatttgta aaaagaattc aagatatcac
    20161 tcgaaacgat gctggtgtta atggtgatgc tcaacgtatt gagcaaatgt cttggttatt
    20221 attcttaaaa atttatgata gccgtgaaat ggtttgggaa ttagaagaag acgagtatga
    20281 gtcaattatc ccagaggaat taaaatggcg aaattgggct catgctcaaa atggggaacg
    20341 ggtattgaca ggcgatgaat tacttgattt tgtcaataac aagttattca aagagttgaa
    20401 agagcttgaa ataacttcaa ttatgcctat tcgaaaaacg attgttaaat cagcttttga
    20461 agatgcgaac aactatatga aaaatggcgt cttgttacgc caagtcatca atgttattga
    20521 tgaagttgat ttcaatagcc ctgaagatcg tcattcgttt aatgatattt acgaaaaaat
    20581 tcttaaagat attcaaaatg ctgggaactc aggagaattt tatacgccac gtgcagcgac
    20641 tgattttatt gccgaagttc ttaacccaaa acttggagaa tcaatggcag accttgcttg
    20701 cggaacagga ggcttcttga cttcgactct gaaccgttta agtagtcaac gtaaaactag
    20761 tgaagatacc aaaaaatata atacagctgt ttttggtatt gaaaagaaag catttcctca
    20821 tcttttagca gttacaaatc tgtttcttca cgaaattgat gaccctaaaa ttgttcatgg
    20881 aaatactttg gagaaaaatg ttcgtgaata tacggatgat gaaaaatttg acattattat
    20941 gatgaatcca ccttttggag ggtcagaatt agaaacaata aaaaataact ttccagcaga
    21001 attacggagt tctgaaacag ctgatttatt tatggctgtc attatgtatc gtttgaaaga
    21061 aaatggtcgt gttggagtta ttttacctga tggttttcta tttggtgaag gtgtaaaaac
    21121 tcgcttgaaa caaaaactgg tagatgagtt caacttgcat acgattatta ggttgcctca
    21181 tagtgtcttt gcaccgtata caggaatcca tacgaacatt cttttctttg ataaaacaaa
    21241 gaaaacagaa gaaacttggt tttatcgttt agatatgcca gatggttata aaaatttctc
    21301 gaaaactaag ccgatgaagt cagaacactt caatcctgtt cgtgactggt gggaaaatcg
    21361 tgaagagatt ctggaaggta agttctacaa atctaaatca tttacaccta gtgaattggc
    21421 tgagttgaat tataatttag accagtgtgg ctttccaaaa gaggaagagg aaatcttaaa
    21481 tccctttgag ttgattcaga attatcaagc ggaaagagca actttaaatc ataagattga
    21541 taatgtatta gctgatattt tgcagttgtt ggaggacaaa taatgacacc agaacaactt
    21601 aaagcaagta ttctccaaag agcgatggaa gggaaattag tgccgcaaaa tcccaatgac
    21661 gaacctgcaa gtgaattatt aaagagaatt aaagctgaaa aagaaaaact tatcagtgaa
    21721 ggaaaaatca aacgagataa aaaggaaact gagatatttc gtggtgatga tg
//
LOCUS       DAVMJI010000034        20300 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.034, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000034 DAVMJI010000000
VERSION     DAVMJI010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20300
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.034"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            14..556
                     /locus_tag="VYR58_001611"
     CDS             14..556
                     /locus_tag="VYR58_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV3622739.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(597..670)
                     /locus_tag="VYR58_001612"
     tRNA            complement(597..670)
                     /locus_tag="VYR58_001612"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(634..636),aa:Asn,seq:gtt)
     gene            complement(676..747)
                     /locus_tag="VYR58_001613"
     tRNA            complement(676..747)
                     /locus_tag="VYR58_001613"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(712..714),aa:Glu,seq:ttc)
     gene            complement(799..1551)
                     /locus_tag="VYR58_001614"
     CDS             complement(799..1551)
                     /locus_tag="VYR58_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3622740.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(1548..2873)
                     /locus_tag="VYR58_001615"
     CDS             complement(1548..2873)
                     /locus_tag="VYR58_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV3622741.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            complement(2894..3019)
                     /gene="comC"
                     /locus_tag="VYR58_001616"
     CDS             complement(2894..3019)
                     /gene="comC"
                     /locus_tag="VYR58_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV3622742.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            complement(3184..3257)
                     /locus_tag="VYR58_001617"
     tRNA            complement(3184..3257)
                     /locus_tag="VYR58_001617"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3221..3223),aa:Arg,seq:tct)
     gene            complement(3301..3780)
                     /gene="rlmH"
                     /locus_tag="VYR58_001618"
     CDS             complement(3301..3780)
                     /gene="rlmH"
                     /locus_tag="VYR58_001618"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV3622743.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            3963..5144
                     /locus_tag="VYR58_001619"
     CDS             3963..5144
                     /locus_tag="VYR58_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV3622744.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            5202..5960
                     /locus_tag="VYR58_001620"
     CDS             5202..5960
                     /locus_tag="VYR58_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV3622745.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            6173..7534
                     /gene="dnaA"
                     /locus_tag="VYR58_001621"
     CDS             6173..7534
                     /gene="dnaA"
                     /locus_tag="VYR58_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV3622746.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            7693..8829
                     /gene="dnaN"
                     /locus_tag="VYR58_001622"
     CDS             7693..8829
                     /gene="dnaN"
                     /locus_tag="VYR58_001622"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV3622747.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            8894..9088
                     /locus_tag="VYR58_001623"
     CDS             8894..9088
                     /locus_tag="VYR58_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV3622748.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANCWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            9172..10287
                     /gene="ychF"
                     /locus_tag="VYR58_001624"
     CDS             9172..10287
                     /gene="ychF"
                     /locus_tag="VYR58_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV3622749.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            10359..10928
                     /locus_tag="VYR58_001625"
     CDS             10359..10928
                     /locus_tag="VYR58_001625"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV3622750.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSIDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            10929..14438
                     /gene="mfd"
                     /locus_tag="VYR58_001626"
     CDS             10929..14438
                     /gene="mfd"
                     /locus_tag="VYR58_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV3622751.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIVASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIHDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            14496..14762
                     /locus_tag="VYR58_001627"
     CDS             14496..14762
                     /locus_tag="VYR58_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV3622752.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            14755..15123
                     /locus_tag="VYR58_001628"
     CDS             14755..15123
                     /locus_tag="VYR58_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV3622753.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            15243..16511
                     /locus_tag="VYR58_001629"
     CDS             15243..16511
                     /locus_tag="VYR58_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV3622754.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFSIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            16508..17785
                     /gene="tilS"
                     /locus_tag="VYR58_001630"
     CDS             16508..17785
                     /gene="tilS"
                     /locus_tag="VYR58_001630"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV3622755.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDEFVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            17789..18331
                     /gene="hpt"
                     /locus_tag="VYR58_001631"
     CDS             17789..18331
                     /gene="hpt"
                     /locus_tag="VYR58_001631"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV3622756.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            18347..>20300
                     /gene="ftsH"
                     /locus_tag="VYR58_001632"
     CDS             18347..>20300
                     /gene="ftsH"
                     /locus_tag="VYR58_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV3622757.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         7023 a         3291 c         3772 g         6214 t
ORIGIN      
        1 acaaggagga aatatgcaag aaagtaacaa acgcttaaaa acaaagcgaa ctattgaaaa
       61 tgctatggta caattactga tggaacagcc atttgataaa atttctactg tcaaattagt
      121 agaaaaagcc ggaattagtc gttccagctt ctatactcac tataaggata agtatgatat
      181 gattgagcac tatcaaagca agctattcca tacatttgaa tatatttttc aaaaacatgc
      241 tcatcacaaa agagacgcta ttttagaagt ttttgaatat ctagagtcag aaccacttct
      301 ggctgccctt ctttctgaaa atgggactaa agaaatccaa aatttcttac gaaataaact
      361 tcatatcatg cttagtacag atttacaaaa gcgatttatg caactgaatc taaataccac
      421 cgaattagaa tatagtagca tctatctaac tcatgcactt tttggtgtct gccaaacttg
      481 gattgcacat ggaaaaaaag aaagttctca agaaataaca gacttcctta tgaaaatgct
      541 tggtgataca aattgataca aaaagaggaa cacagctgtg ttccctttta tctatactcc
      601 gccagtagga ctcgaaccta cgacatcatg attaacagtc atgcgctact accaactgag
      661 ctatggcgga taaaatagtc cgtacgggat tcgaacccgt gttaccgccg tgaaaaggcg
      721 gtgtcttaac cccttgacca acggaccttc tatctgtagc agatataacc attatatcaa
      781 tttcttgcta attgtcaatc acttttgaga ttttttctct aaaatatctt ttaattttct
      841 aatttttaat cttgaaatag gacaacgatg gtcttcatag aaaacaattt ctaagttttt
      901 tcgatcaatt tctctgatat tgcctatatt taccaaaaat gacttgtgag gagaataaaa
      961 tcgctgagta tgtttgtcct tttcctgaat atctgtcatg gtaccataaa actcttttgc
     1021 aaaattctta ccaataatgc gcaatttatg agagacccct gttgtttcaa tatacaaaat
     1081 atcatggtaa ggaattttta aatcatttcc tttgtaattg tagtcgaaat aatctacaac
     1141 atcttcattt tcaagtaaca tactcttcgt gtagaagata ttttgctcaa ttctcttctt
     1201 aaacatctca tcattgatat ccttatcaac aaaatctagg gctgatacct ggtatttata
     1261 ggttagagtc gcaaactctg atcgactagt gataaagacg ataatagcgt aaggattgta
     1321 atgacgaatg agctgagcca cttcaaatcc ctttttctca attccatgaa tatcgatatc
     1381 taggaaataa agctgattta cttcatcatt ttcaatgtat tcttcaaatt cacggacttt
     1441 tcccgttgtc ttgtatgata ttggaatatt cgattctttc gaaatttcat ccaatattct
     1501 ctctagtctc acttgatgtt caataacatc ttctaaaatt aaaactttca ttcaaattcc
     1561 ctcttaaatc taatgatttg tctaaatgta ctgccttcca tctctgtttc taaaataata
     1621 ttgttgtact tatctagtag ttctttcaca ttatttaatc cgactccgcg atttcttccc
     1681 ttagtggaga atcctaaggc aaatagatct cctgaaggag tcatcgtcat tttacatgaa
     1741 ttctgaatca caataactgt ttcagtttcc atcttaataa ctgctacttc catctgcttt
     1801 ttatagctat cagccgatcc ttcgacagca ttattcaata aaacgctcat gatacgaacc
     1861 aaatccaata gttcaattgg aagcttggta atcgtatctt ttacttccag tgtaaactct
     1921 acaccattat ttcgagcata gacaattgac tgagcaacca aacttcgtaa agctgagtct
     1981 tctatgttgt tcaaatcaaa gtaagtgtac ttatctgaac gcaatttatg atttgctttg
     2041 actaaaactt cattgtaaat tctgtcaatt tcctgtaaat taccactgtc aattgccatc
     2101 tgcatgctga caagcattcc agcataatca tgtcgaaaac cacggatttc attatacaga
     2161 ccaacaattt catctgtgta attctgtaaa tgtttctgtt caaatttctt ctgcttcaaa
     2221 gcaatctctt tctccatttg aactttatga gaattcattg caaagaaggt caaaaggaga
     2281 gagataaaga caatagatga caaaatactt ccaaaactat tcaaatgttt aatcgtactt
     2341 accatatctg aaacgaaaga tacaatatgt agcaatagta aagcaaaaaa tacttttttc
     2401 aagaaaggat aaaggtagtc ctcgtcaaaa taggctagtt ccaaatggaa atagtaaatg
     2461 atttttaatg taacaaaata ggttaacacc gtcacaacga aaaagaatgg gaaatgatat
     2521 tgtaaaacaa aattatctcc tgttatagag gagaaagtta cggacagaaa gttatgagtg
     2581 ctctcatata aaagagatag tagtaaactt aggaatagtc ctctatccct ctcatactgt
     2641 ttcatccatc gaaaatagga atataatccc aaaggaaata aaaatctttc aatccctaac
     2701 ccatctaaat atagaatata taagggaaaa tcaaatacta tttctgttag taatgtataa
     2761 gcaccaaaaa cgaataattc ttttctattt atttgacctt tacaaataaa atggtaactg
     2821 tgactaataa ttaaaaaatg aacaataacc gtcccaaatc caaataaatc cattactctt
     2881 tccccttatt tcattacttt tttctttgta aaataaaatc acggaagaat tttgacaacc
     2941 tcatctcccc acctttaatc ttttgtaagt ctttttcctt caaagctaca aactgttcca
     3001 atttaactgt gtttttcata ataaaatctc ctaaaatgtt ttttcttgta agctaactta
     3061 caaaaaccat tatacaaaat ggaatttcgt tttagataaa attctctcaa ctgtcatttt
     3121 tttctcccaa agtgtacttt tttaagaaaa aagccgggaa aattcccagc tttgctatta
     3181 tattgatccc agcaggattc gaacctgcga ccgttcgctt agaaggcgaa tgctctatcc
     3241 agctgagcta tgagacctaa tacaattatt ctaccaaaaa ttcaattaaa agtcaatttt
     3301 ctatttatgg taggggaatc cctgctgaat cgtaaaagcg cgatagattt gttcaacaag
     3361 aactagtctc attaactgat ggggtaaggt taggcgacca aaactgacag aaagattggc
     3421 tctatttttt acagatgatg acaatcctaa acttccccca ataataaaag taagagtaga
     3481 aaatcctttt atagaagttt cttctaactg cttactaaat tcttctgaga agaaagtttt
     3541 cccttcaatg gctaacacaa taacgaaatc acggtcagca atttttgata aaattctctg
     3601 accttctatt tctaaaatct tttgattttc tgattcactg gccttatctg gtgttttttc
     3661 atctgataac tcaatcattt caaacttagc aaatctagaa attcgttttg aatactctgc
     3721 gataccatct tttaaatact tttctttcag tttcccaact gttacaactt taattttcat
     3781 gactctattc taacatattc tctatttttt cacatcttat tcacaaaata aaaaatagat
     3841 ttcaattaag aaaatcacag tttcaaaaga gttatccaca gtttgtgtaa aacttttgtg
     3901 tttaagttat aattaagcta gtcagtttat actttcagta attcaaacat atggaggcaa
     3961 atatgaaaca tctaaaaaca ttttacaaaa aatggtttca attattagtc gttatcgtca
     4021 ttagcttttt tagtggagcc ttgggtagtt tttcaataac tcaactaact caaaaaagta
     4081 gtgtaaacaa ctctaacaac aatagtacta ttacacaaac tgcctataag aacgaaaatt
     4141 caacaacaca ggctgttaac aaagtaaaag atgctgttgt ttctgttatt acttattcgg
     4201 caaacagaca aaatagcgta tttggcaatg atgatactga cacagattct cagcgaatct
     4261 ctagtgaagg atctggagtt atttataaaa agaatgataa agaagcttac atcgtcacca
     4321 acaatcacgt tataaatggc gccagcaaag tagatattcg attgtcagat gggactaaag
     4381 tacctggaga aattgtcgga gctgacactt tctctgatat tgctgtcgta aaaatctctt
     4441 cagaaaaagt gacaacagta gctgagtttg gtgattctag taagttaact gtaggagaaa
     4501 ctgctattgc catcggtagc ccgttaggtt ctgaatatgc aaatactgtc actcaaggta
     4561 tcgtatccag tctcaataga aatgtatcct taaaatcgga agatggacaa gctatttcta
     4621 caaaagccat ccaaactgat actgctatta acccaggtaa ctctggcggc ccactgatca
     4681 atattcaagg gcaggttatc ggaattacct caagtaaaat tgctacaaat ggaggaacat
     4741 ctgtagaagg tcttggtttc gcaattcctg caaatgatgc tatcaatatt attgaacagt
     4801 tagaaaaaaa cggaaaagtg acgcgtccag ctttgggaat ccagatggtt aatttatcta
     4861 atgtgagtac aagcgacatc agaagactca atattccaag taatgttaca tctggtgtag
     4921 ttgttcgttc ggtacaaagt aatatgcctg ccaatggtca ccttgaaaaa tacgatgtaa
     4981 ttacaaaagt agatgacaaa gagattgctt catcaacaga cttacaaagt gctctttaca
     5041 accattctat cggagacacc attaagataa cctactatcg taacgggaaa gaagaaacta
     5101 cctctatcaa acttaacaag agttcaggtg atttagaatc ttaattgaca tctatgtaaa
     5161 gaaagcttta cataagagaa aagatgtgtt agtgtagaat catggaaaaa tttgaaatga
     5221 tttctatcac agatatacaa aaaaatccct atcaaccccg aaaagaattt gatagagaaa
     5281 aactagatga actagcacag tctatcaaag aaaatggggt cattcaaccg attattgttc
     5341 gtcaatctcc tgttattggt tatgaaatcc ttgcaggaga gagacgctat cgggcttcac
     5401 ttttagctgg tctacggtct atcccagctg ttgttaaaca gatttcagac caagagatga
     5461 tggtccagtc cattattgaa aatttacaga gagaaaattt aaacccaata gaagaagcac
     5521 gcgcctatga atctctcgta gagaaaggat tcacccatgc tgaaattgca gataagatgg
     5581 gcaagtctcg tccatatatc agcaactcca ttcgtttact ttccttgcca gaacagattc
     5641 tttcagaagt agaaaatggc aaactatcac aagcccatgc gcgttcccta gttgggttaa
     5701 ataaggaaca acaagactat ttctttcaac ggattataga agaagatatt tctgtaagga
     5761 aattagaagc tcttctgaca gagaaaaaac aaaagaaaca gcaaaaaact aatcatttca
     5821 tacaaaatga agaaaaacag ttaagaaaac tactcggatt agatgtagaa attaaactat
     5881 ctaaaaaaga cagtggaaaa atcattattt ctttttcaaa tcaagaagaa tatagtagaa
     5941 ttatcaacag cctgaaataa ggctgttctt ttattttttt atctcacaag gttatccact
     6001 atgtttttcg ataaaaagct taataaatca ataatttctt cttttatccc caacctgtgg
     6061 ataaagtttg gtaacattgt ggattatttt tcacagcttg tggaaaattc ttgctatcta
     6121 tggtaaaata tctctagtat taaactttta aatagtaaag gaggagaaag gattgaaaga
     6181 aaaacaattt tggaatcgta tattagaatt tgcacaagaa agactgactc gatccatgta
     6241 tgatttctat gctattcaag ctgaactcat caaggtagag gaaaatgttg ccactatatt
     6301 tctacctcgc tctgaaatgg aaatggtctg ggaaaaacaa ctaaaagata ttattgtagt
     6361 agctggtttt gaaatttatg acgctgaaat aactccccac tatattttca ccaaacctca
     6421 agatacgact agctcacaag ttgaagaagc tacaaattta actctttata actatagtcc
     6481 aaagttagta tctattcctt attcagatac gggattaaaa gaaaagtata cctttgataa
     6541 ctttattcaa ggggatggaa atgtttgggc tgtgtcagcc gctttagctg tctctgaaga
     6601 tttggctctg acctataacc ctctttttat ctatggagga ccaggccttg gtaagactca
     6661 cttattaaac gctattggaa atgaaattct aaaaaatatt cctaatgcgc gtgttaaata
     6721 tatccctgcc gaaagcttta ttaatgactt tcttgatcac ctaagacttg gggaaatgga
     6781 aaagtttaaa aagacctatc gtagtcttga tcttttgtta atcgatgata tccagtcact
     6841 cagcggaaaa aaagtcgcaa ctcaggaaga atttttcaat acctttaacg cccttcatga
     6901 caagcaaaaa cagattgtcc taacgagtga tcgtagtcca aaacatctag aagggctcga
     6961 ggagaggctt gtcacgcgtt ttagttgggg attgacacaa actatcacac cccctgactt
     7021 tgaaacacgt attgccattt tacaaagtaa aacggaacat ttaggctaca atttccaaag
     7081 tgatactcta gaatacctag ctgggcaatt tgattcaaat gttcgagatc ttgagggagc
     7141 catcaacgac atcactttaa ttgccagagt aaaaaaaatc aaggatatca ctattgatat
     7201 tgctgcagaa gccattagag cccgcaaaca agatgttagc caaatgctcg tcatcccaat
     7261 tgataaaatc caaactgaag ttggtaactt ttatggtgtt agtatcaaag aaatgaaggg
     7321 aagtagacgc cttcaaaata ttgttttggc ccgtcaagta gccatgtatt tatctagaga
     7381 actaacagat aatagtcttc caaaaattgg gaaggaattt gggggaaaag atcataccac
     7441 agtcattcat gcccatgcca aaataaaatc tttgattgat caagacgata atttacgttt
     7501 agaaattgaa tcaatcaaaa agaaaatcaa ataatttgtg gataactttt agttttttat
     7561 cttttttatc cacatttttt aaacaagcta aaaaacttga tatgacttgt ttaaaggctg
     7621 ttttccacag atttcacaga ctctattatt actattatct ttctaatact aaaaataaat
     7681 aaaggagaat ccatgattca tttttcaatt aataaaaatt tatttctaca agcattaaat
     7741 actactaaga gagctattag ttctaaaaat gccattccta ttttatcaac agtaaaaatt
     7801 gacgtgacca atgaaggtat tactttaatt ggttcaaatg gtcaaatttc aattgaaaat
     7861 tttatttctc aaaaaaatga agatgctggt ttgttaatta cttctttagg ttcgatcctt
     7921 cttgaagctt ctttctttat caatgtagta tctagtttac ctgatgtaac tcttgatttt
     7981 aaagaaattg aacaaaatca aattgtttta accagtggca aatcagaaat taccctaaaa
     8041 ggaaaagata gcgaacaata tccacgaatc caagaaattt cagcaagcac tcctttaata
     8101 cttgaaacaa aattactcaa gaaaattatt aatgaaacag cctttgctgc aagtacacaa
     8161 gagagtcgtc cgattttaac aggtgtccac ttcgtattga gtcaacacaa agagttaaaa
     8221 acagttgcaa cagactctca tcgcctaagc cagaaaaaat tgactcttga aaaaaatagt
     8281 gatgattttg atgtcgtaat tcctagccgt tctctacgcg aattttcagc ggtatttaca
     8341 gatgatatcg aaactgtaga gattttcttt gccaataacc aaatcctctt tagaagcgaa
     8401 aatattagct tctatactcg tctcctagaa ggaaactatc ctgatacaga tcgcttgatt
     8461 ccaacagact ttaacactac tattactttt aatgtggtaa acttacgcca gtcaatggag
     8521 cgtgcccgtc ttttatcaag tgcgactcaa aatggtactg tgaaacttga aattaaggat
     8581 ggggttgtta gcgcccatgt tcactctcca gaagttggta aagtaaacga agaaatcgat
     8641 actgatcagg ttactggtga agatttgacc attagtttca acccaactta cttgattgat
     8701 tctcttaaag ctttaaatag cgaaaaggtg accattagct ttatctcagc tgttcgtcca
     8761 tttactcttg tgccagcaga tactgacgaa gacttcatgc agctcattac accagttcgt
     8821 acaaattaag tgaaagaggt tgagcctggc tcgcctcttt tatgatataa tcgaaaaaga
     8881 aaaggagagt agtatgtatc aagttggaaa ttttgttgag atgaaaaaat cacacgcttg
     8941 tacaatcaag tcgactggta aaaaggctaa ttgttgggaa attacacgtg taggagcaga
     9001 tatcaaaata aaatgcagta attgtgagca tgttgtcatg atggggcgat atgattttga
     9061 gcgaaaaatg aataaaatta ttgactgaga acccttagtt agagggttag cactttatcc
     9121 ctttttgtgt tataatatta gggattgaaa tgaaaacgga gaatgagaaa tatggctttg
     9181 acagcaggta tcgttggttt gccaaacgtt ggtaaatcaa cactatttaa tgcaattaca
     9241 aaagcaggag cagaggcagc aaactaccca tttgcgacga ttgatccaaa tgttggaatg
     9301 gtggaagttc cagatgaacg cctacaaaaa ctaactgaaa tgataactcc taaaaaaaca
     9361 gttcccacaa catttgaatt tacggatatt gcagggattg taaaaggagc ttcaaaagga
     9421 gaagggctag ggaataaatt cttggccaat attcgtgaag tagatgcgat tgttcacgta
     9481 gttcgtgctt ttgatgatga aaatgtgatg cgcgagcaag gacgtgaaga cgcctttgta
     9541 gatccacttg cagatattga tacaattaat ctggaattaa ttcttgctga cttagaatca
     9601 gtgaacaaac gatatgcgcg tgtagaaaag atggcacgta cgcaaaaaga taaagaatca
     9661 gtagcagaat tcaatgttct tcaaaagatt aaaccagtcc tagaagacgg gaaatcagct
     9721 cgtaccattg aatttacaga tgaggaacaa aaggttgtca aaggtctttt ccttttgacg
     9781 actaaaccag ttctttatgt agctaatgtg gacgaggatg tggtttcaga acctgactct
     9841 atcgactatg tcaaacaaat tcgtgaattt gcagcgacag aaaatgctga agtagtcgtt
     9901 atttctgcgc gtgctgagga agaaatttct gaattggatg atgaagataa aaaagagttt
     9961 cttgaagcca ttggtttgac agaatcaggt gtagataagt tgacgcgtgc agcttaccac
    10021 ttgcttggat tgggaactta cttcacagct ggtgaaaaag aagttcgcgc ttggactttc
    10081 aaacgtggta tgaaggctcc tcaagcagct ggtattatcc actcagactt tgaaaaaggc
    10141 tttattcgtg cagtaaccat gtcatatgaa gatctagtga aatacggatc tgaaaaggcc
    10201 gtaaaagaag ctggacgctt gcgtgaagaa ggaaaagaat atatcgttca agatggcgat
    10261 atcatggaat tccgctttaa tgtctaaaaa ttaataaatg gtgtcaatta ggttggaaaa
    10321 aaaattccaa cccttttggc ttttgaaagg aaaaataaat gaccaaatta cttgtaggct
    10381 tgggaaatcc aggggataaa tattttgaaa caaaacacaa tgttggtttt atgttgattg
    10441 atcaactagc gaagaaacag aatgtcactt ttacacacga taagatattt caagctgacc
    10501 tagcatcctt tttcctaaat ggagaaaaaa tttatctggt taaaccaacg acctttatga
    10561 atgaaagtgg aaaagcagtt catgctttat taacttacta tggtttggat attgacgatt
    10621 tacttatcat ttacgatgat cttgacatgg aagttgggaa aattcgttta agagcaaaag
    10681 gctcagcagg tggtcataat ggtatcaagt ctattattca acatatagga actcaggtct
    10741 ttaaccgtgt taagattgga attggaagac ctaaaaatgg tatgtcagtt gttcatcatg
    10801 ttttgagtaa gtttgacagg gatgattata tcggtatttt acagtctatt gacaaagttg
    10861 acgattctgt aaactactat ttacaagaga aaaattttga gaaaacaatg cagaggtata
    10921 acggataaat ggtgacctta ttagatttat tctcagaaaa tgatcagatt aaaaaatggc
    10981 atcaaaattt aacagataag aaaagacaac taatacttgg tttatcaaca tctactaagg
    11041 ctcttgcaat tgcaagcagt ttagaaaaag aagataggat tgtgttattg acgtcaactt
    11101 atggagaagc agaaggactt gttagtgatc ttatatctat cttgggtgag gaactcgtct
    11161 atccattttt ggtagatgat gctcctatgg tggagttttt gatgtcttca caggaaaaaa
    11221 ttatttcacg ggttgaagcc ttgcgttttt tgactgattc atctaagaaa gggattttag
    11281 tttgtaatat cgtagcaagt cgattgattt taccgtctcc caatgcattc aaagatagta
    11341 ttgtaaaaat ctcagttggt gaagaatatg atcaacacgc gtttatccat cagttaaagg
    11401 aaaatggcta tcgaaaagtt actcaagtac aaactcaggg cgaatttagt cttcgaggag
    11461 atattttaga tatttttgaa atatcccagt tagaaccttg tcgaattgag ttttttggtg
    11521 atgaaattga tggtatcagg tcatttgaag tagaaacaca attatcgaaa gaaaataaga
    11581 cagaactcac tatctttcca gctagtgata tgcttttgag agaaaaggat tatcaacgag
    11641 gacagtcagc tttagaaaaa caaatttcaa aaactttatc acctattttg aaatcatacc
    11701 tagaagaaat tctttcaagt tttcaccaaa aacaaagtca tgcagactct cggaagtttt
    11761 tatctttgtg ctatgataag acatggactg tctttgatta tattgaaaaa gataccccaa
    11821 tattctttga tgattatcaa aaattgatga atcagtatga agtctttgaa agagacttag
    11881 cgcagtactt tacagaagaa ttacagaata gtaaagcatt ttctgatatg cagtattttt
    11941 ctgatattga acaaatctat aaaaaacaaa gtccagtgac ctttttctct aatcttcaaa
    12001 agggtttagg aaatctcaaa tttgacaaaa tttatcaatt caatcaatat cctatgcagg
    12061 aatttttcaa tcagttttct tttctaaaag aagaaattga acgatataaa aaaatggatt
    12121 acaccattat tctgcagtct agcaattcaa tgggaagtaa aacattggag gatatgttag
    12181 aggaatatca gattaaattg gattctagag ataagacaaa tatctgtaaa gaatctgtaa
    12241 acttaataga gggtaatctc agacatggtt ttcattttgt agatgaaaag attttattga
    12301 taactgaaca tgagattttt caaaagaaat taaagcgtcg ttttcgaaga caacatgttt
    12361 caaatgcaga gagattaaaa gattacaatg aacttgaaaa aggggactat gttgtccatc
    12421 atatccatgg gattggtcaa tatctaggaa ttgaaaccat tgaaatcaag ggaattcatc
    12481 gcgattatgt cagtgtccaa taccaaaatg gtgatcaaat ttctatcccc gtggaacaga
    12541 ttcatctact gtccaaatat atttcaagtg atggtaaagc tccaaaactc aataaattaa
    12601 atgacggtca ttttaaaaag gccaagcaaa aggttaagaa ccaggtagag gatatagctg
    12661 atgatttaat caaactctac tctgaacgta gtcagttgaa gggttttgct ttctcagctg
    12721 atgatgatga tcaagatgcc tttgatgatg ctttccctta tgttgaaacg gatgatcaac
    12781 ttcgtagtat tgaggaaatc aagagggata tgcaggcttc tcagccaatg gatcgacttt
    12841 tagttgggga tgttggtttt ggaaagactg aagttgctat gcgtgcagcc tttaaagcag
    12901 tcaatgatca caaacaggtt gtcattctag ttccgacgac ggttttagcg caacagcact
    12961 atacgaattt taaggaacga ttccaaaatt ttgcagttaa tattgatgtg ttgagtcgct
    13021 ttagaagtaa aaaagagcag actgcaacac ttgaaaaatt gaaaaacggt caagtcgata
    13081 ttttgattgg aacacatcgt gttttgtcaa aagatgttgt gtttgctgat ttgggcttga
    13141 tgattattga tgaggaacag cgatttggtg tcaagcataa ggaaactttg aaagaactga
    13201 agaaacaagt ggatgtccta accttgaccg ctacgccaat ccctcgtacc ctccatatgt
    13261 ctatgctggg aatcagagat ttatctgtta ttgaaactcc gccgactaat cgctatcctg
    13321 ttcagaccta tgttttggaa aagaatgata gtgtcattca tgatgctgtc ttgcgtgaaa
    13381 tggagcgtgg aggtcaagtt tattatcttt acaacaaagt tgacacaatt gttcagaagg
    13441 tttcagaatt acaggagttg attccggagg cttcgattgg atatgttcat ggtcgaatga
    13501 gtgaagtcca gttggaaaat actctattag actttattga gggacaatac gatatcttgg
    13561 tgacgactac tattattgag acaggggtgg acattccaaa tgctaatact ttatttattg
    13621 aaaatgcgga ccatatgggc ttgtcaacct tatatcagtt aagaggaaga gtcggtcgta
    13681 gtaatcgtat tgcttatgct tatctcatgt atcgtccaga aaaatcaatc agtgaagtct
    13741 ctgaaaagag attagaagcg attaaaggat ttacagaatt gggctctggc tttaagattg
    13801 caatgcgaga tctttcgatt cgtggagcag gaaatctttt aggaaaatcc cagtctggtt
    13861 tcattgattc tgttggtttt gaattgtatt cgcagttatt agaggaagct attgctaaac
    13921 gaaacggtaa tgctaacgct aacacaagaa ccaaagggaa tgctgagttg attttgcaaa
    13981 ttgatgccta tcttcctgat acttatattt ctgatcaacg acataagatt gaaatttaca
    14041 agaaaattcg tcaaattgac aaccgtgtca attatgaaga gttacaagag gagttgatag
    14101 accgttttgg agaataccca gatgtagtag cctatctttt agagattggt ttggttaaat
    14161 catacttgga caaggtcttt gttcaacgtg tggaaagaaa agataataaa attacaattc
    14221 aatttgaaaa agtcactcaa cggctgtttt tagctcaaga ttattttaaa gctttatccg
    14281 taacgaactt aaaagcaggc atcgctgaga ataagggatt aatggagctt gtatttgatg
    14341 tccaaaataa gaaagattat gaaattttag aaggtctgct gatttttgga gaaagtttat
    14401 tagagataaa agagtttaag gaagaaaatt ccatttgata tttttcttct ataaaataga
    14461 taaaaatggt acaataataa attgaggtaa taaggatgag attagataaa tatttaaaag
    14521 tatcgcgaat tatcaagcgt cgtacagtcg caaaggaagt agcagataaa ggtagaatca
    14581 aggttaatgg aatcttggcc aaaagttcaa cggacttgaa agttaatgac caagttgaaa
    14641 ttcgctttgg caataagttg ctgcttgtaa aagtactaga gatgaaagat agtacaaaaa
    14701 aagaagatgc agcaggaatg tatgaaatta tcagtgaaac acgggtagaa gaaaatgtct
    14761 aaaaatattg tacaattgaa taattctttt attcaaaatg aataccaacg tcgtcgctac
    14821 ctgatgaaag aacgacaaaa acggaatcgt tttatgggag gggtattgat tttgattatg
    14881 ctattattta tcttgccaac ttttaattta gcgcagagtt atcagcaatt actccaaaga
    14941 cgtcagcaat tagcagactt gcaaactcag tatcaaactt tgagtgatga aaaggataag
    15001 gagacagcat ttgctaccaa gttgaaagat gaagattatg ctgctaaata tacacgagcg
    15061 aagtactatt attctaagtc gagggaaaaa gtttatacga ttcctgactt gcttcaaagg
    15121 tgataaaatg gaaaatttat tagacgtaat agagcaattt ttgagtttgt cagatgaaaa
    15181 gctggaagaa ttggctgata aaaatcaatt attgcgttta caagaagaaa aggaaaggaa
    15241 gaatgcgtaa attcttaatt attttgttgc taccaagttt tttgaccatt tcaaaagtcg
    15301 ttagcacaga aaaagaagtc gtctatactt cgaaagaaat ttattacctt tcacaatctg
    15361 actttagtat ttattttaga gaaaaattaa gttctcccat ggtttatgga gaggttcctg
    15421 tttatgcgaa tgaagattta gtagtggaat ctgggaaatt gactcccaaa acaagttttc
    15481 aaataaccga gtggcgctta aataaacaag gaattccagt atttaagcta tcaaatcatc
    15541 aatttatagc tgcggacaaa cgatttttat atgatcaatc agaggtaact ccaacaataa
    15601 aaaaagcatg gttagaatct gactttaaac tgtacaatag tccttatgat ttaaaagaag
    15661 tgaaatcatc cttatcagct tattcgcaag tatcaatcga caagaccatg tttgtagaag
    15721 gaagagaatt tctacatatt gatcaggctg gatgggtagc taaagaatca acttctgaag
    15781 aagataatcg gatgagtaaa gttcaagaaa tgttatctga aaaatatcag aaagattctt
    15841 tctctattta tgttaagcaa ctgactactg gaaaagaagc tggtatcaat caagatgaaa
    15901 agatgtatgc agccagcgtt ttgaaactct cctatctcta ttatacgcaa gaaaaaataa
    15961 atgagggtct ttatcagtta gatacgactg taaaatacgt atctgcagtc aatgattttc
    16021 caggttctta taaaccagag ggaagtggta gtcttcctaa aaaagaagat aataaagaat
    16081 attctttaaa ggatttaatt acgaaagtat caaaagaatc tgataatgta gctcataatc
    16141 tattgggata ttacatttca aaccaatctg atgccacatt caaatccaag atgtctgcca
    16201 ttatgggaga tgattgggat ccaaaagaaa aattgatttc ttctaagatg gccgggaagt
    16261 ttatggaagc tatttataat caaaatggat ttgtgctaga gtctttgact aaaacagatt
    16321 ttgatagtca gcgaattgcc aaaggtgttt ctgttaaagt agctcataaa attggagatg
    16381 cggatgaatt taagcatgat acgggtgttg tctatgcaga ttctccattt attctttcta
    16441 ttttcactaa gaattctgat tatgatacga tttctaagat agccaaggat gtttatgagg
    16501 ttctaaaatg agggaaccag attttttaaa tcattttctc aagaagggat atttcaaaaa
    16561 gcatgctaag gcggttctag ctctttctgg tggattagat tccatgtttc tatttaaggt
    16621 attgtctact tatcaaaaag agttagagat tgaattgatt ctagctcatg tgaatcataa
    16681 gcagagaatt gaatcagatt gggaagaaaa ggaattaagg aagttggctg ctgaagcaga
    16741 gcttcctatt tatatcagca atttttcagg agaattttca gaagcgcgtg cacgaaattt
    16801 tcgttatgat ttttttcaag aggtcatgaa aaagacaggt gcgacagctt tagtcactgc
    16861 ccaccatgct gatgatcagg tggaaacgat tttgatgcgc ttgattcgag gaactcgctt
    16921 gcgctatcta tcaggaatta aggagaagca agtagtcgga gagatagaaa tcattcgtcc
    16981 cttcttgcat tttcagaaaa aagactttcc atcaattttt cactttgaag atacatcaaa
    17041 tcaggagaat cattattttc gaaatcgtat tcgaaattct tacttaccag aattggaaaa
    17101 agaaaatcct cgatttaggg atgcaatctt aggcatcggc aatgaaattt tagattatga
    17161 tttggcaata gctgaattat ctaacaatat taatgtggaa aatttacagc agttattttc
    17221 ttactctgag tctacacaaa gagttttact tcaaacttat ctgaatcgtt ttccagattt
    17281 gaatcttaca aaagctcagt ttgctgaagt tcagcagatt ttaaaatcta aaagccagta
    17341 tcgtcatccg attaaaaatg gctatgaatt gataaaagag taccaacagt ttcagatttg
    17401 taaaatcagt ccgcaggctg atgaagagga agatgaattt gtgttacact atcaaaatca
    17461 ggtagcttat caaggatatt tattttcctt tggacttcca ttagaaggtg aattaattca
    17521 acaaatacct gtttcacgtg aaacatccat acacattcgt catcgaaaaa caggagatgt
    17581 tttgattcaa aatgggcata gaaaaaaact cagacgttta tttattgatt tgaaaatccc
    17641 tatggaaaag agaaactctg ctcttattat tgagcaattt ggtgaaattg tctcaatttt
    17701 gggaattgcg accaataatt tgagtaaaaa aacgaaaaat gatataatga acactgtact
    17761 ttatatagaa aaaatagata ggtaaaaaat gttagaaaac gatattaaaa aagtcctcgt
    17821 ttcacacgat gaaattacag aagcagctaa aaaactaggt gctcaattaa ctaaagacta
    17881 tgcaggaaaa aatccaatct tagttgggat tttaaaagga tctattcctt ttatggctga
    17941 attggtcaaa catattgata cacatattga aatggacttc atgatggttt ctagctacca
    18001 tggtggaaca gcaagtagtg gtgttatcaa tattaaacaa gatgtgactc aagatatcaa
    18061 aggaagacat gttctatttg tagaagatat cattgataca ggtcaaactt tgaagaattt
    18121 gcgagatatg tttaaagaaa gagaagcagc ttctgttaaa attgcaacct tgttggataa
    18181 accagaagga cgtgttgtag aaattgaggc agactatacc tgctttacta tcccaaatga
    18241 gtttgtagta ggttatggtt tagactacaa agaaaattat cgtaatcttc cttatattgg
    18301 agtattgaaa gaggaagtgt attcaaatta gaaagaataa tctttaatga aaaaacaaaa
    18361 taatggttta attaaaaatc cttttctatg gttattattt atctttttcc ttgtgacagg
    18421 attccagtat ttctattctg ggaataactc aggaggaagt cagcaaatca actatactga
    18481 gttggtacaa gaaattaccg atggtaatgt aaaagaatta acttaccaac caaatggtag
    18541 tgttatcgaa gtttctggtg tctataaaaa tcctaaaaca agtaaagaag gaacaggtat
    18601 tcagtttttc acgccatctg ttactaaggt agagaaattt accagcacta ttcttcctgc
    18661 agatactacc gtatcagaat tgcaaaaact tgctactgac cataaagcag aagtaactgt
    18721 taagcatgaa agttcaagtg gtatatggat taatctactc gtatccattg tgccatttgg
    18781 aattctattc ttcttcctat tctctatgat gggaaatatg ggaggaggca atggccgtaa
    18841 tccaatgagt tttggacgta gtaaggctaa agcagcaaat aaagaagata ttaaagtaag
    18901 attttcagat gttgctggag ctgaagaaga aaaacaagaa ctagttgaag ttgttgagtt
    18961 cttaaaagat ccaaaacgat tcacaaaact tggagcccgt attccagcag gtgttctttt
    19021 ggagggacct ccggggacag gtaaaacttt gcttgctaag gcagtcgctg gagaagcagg
    19081 tgttccattc tttagtatct caggttctga ctttgtagaa atgtttgtcg gagttggagc
    19141 tagtcgtgtt cgctctcttt ttgaggatgc caaaaaagca gcaccagcta tcatctttat
    19201 cgatgaaatt gatgctgttg gacgtcaacg tggagtcggt ctcggcggag gtaatgacga
    19261 acgtgaacaa accttgaacc aacttttgat tgagatggat ggttttgagg gaaatgaagg
    19321 gattatcgtc atcgctgcga caaaccgttc agatgtactt gatcctgccc ttttgcgtcc
    19381 aggacgtttt gatagaaaag tattggttgg ccgtcctgat gttaaaggtc gtgaagcaat
    19441 cttgaaagtt cacgctaaga acaagccttt agcagaagat gttgatttga aattagtggc
    19501 tcaacaaact ccaggctttg ttggtgctga tttagagaat gtcttgaatg aagcagcttt
    19561 agttgctgct cgtcgcaata aatcgataat tgatgcttca gatattgatg aagcagaaga
    19621 tagagttatt gctggacctt ctaagaaaga taagacagtt tcacaaaaag aacgagaatt
    19681 ggttgcttac catgaggcag gacataccat tgttggtcta gtcttgtcga atgctcgcgt
    19741 tgtccataag gttacaattg taccacgcgg ccgtgcaggc ggatacatga ttgcacttcc
    19801 taaagaggat caaatgcttc tatctaaaga agatatgaaa gagcaattgg ctggcttaat
    19861 gggtggacgt gtagctgaag aaattatctt taatgtccaa actacaggag cttcaaacga
    19921 ctttgaacaa gcgacacaaa tggcacgtgc aatggttaca gagtacggta tgagtgaaaa
    19981 acttggccca gtacaatatg aaggaaacca tgctatgctt ggtgcacaga gtcctcaaaa
    20041 atcaatttca gaacaaacag cttatgaaat tgatgaagag gttcgttcat tattaaatga
    20101 ggcacgaaat aaagctgctg aaattattca gtcaaatcgt gaaactcaca agttaattgc
    20161 agaagcatta ttgaaatacg aaacattgga tagtacacaa attaaagctc tttacgaaac
    20221 aggaaagatg cctgaagcag tagaagagga atctcatgca ctatcctatg atgaagtaaa
    20281 gtcaaaaatg aatgacgaaa
//
LOCUS       DAVMJI010000035        19814 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.035, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000035 DAVMJI010000000
VERSION     DAVMJI010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19814
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.035"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(118..915)
                     /locus_tag="VYR58_001633"
                     /pseudo
     CDS             complement(118..915)
                     /locus_tag="VYR58_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1181..1417
                     /locus_tag="VYR58_001634"
     CDS             1181..1417
                     /locus_tag="VYR58_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV3622758.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1648..2934
                     /locus_tag="VYR58_001635"
     CDS             1648..2934
                     /locus_tag="VYR58_001635"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV3622759.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            3135..3602
                     /locus_tag="VYR58_001636"
     CDS             3135..3602
                     /locus_tag="VYR58_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV3622760.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            3635..3728
                     /gene="ffs"
                     /locus_tag="VYR58_001637"
     ncRNA           3635..3728
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYR58_001637"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3811..4952)
                     /locus_tag="VYR58_001638"
                     /pseudo
     CDS             complement(3811..4952)
                     /locus_tag="VYR58_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(5007..6077)
                     /locus_tag="VYR58_001639"
     CDS             complement(5007..6077)
                     /locus_tag="VYR58_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HEV3622761.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            complement(6094..6474)
                     /locus_tag="VYR58_001640"
     CDS             complement(6094..6474)
                     /locus_tag="VYR58_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV3622762.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            complement(6487..6750)
                     /locus_tag="VYR58_001641"
     CDS             complement(6487..6750)
                     /locus_tag="VYR58_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV3622763.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(6750..6983)
                     /locus_tag="VYR58_001642"
     CDS             complement(6750..6983)
                     /locus_tag="VYR58_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622764.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            complement(6983..7351)
                     /locus_tag="VYR58_001643"
     CDS             complement(6983..7351)
                     /locus_tag="VYR58_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3622765.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            7923..8114
                     /locus_tag="VYR58_001644"
     CDS             7923..8114
                     /locus_tag="VYR58_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV3622766.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            8137..8340
                     /locus_tag="VYR58_001645"
     CDS             8137..8340
                     /locus_tag="VYR58_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622767.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(8495..8662)
                     /locus_tag="VYR58_001646"
     CDS             complement(8495..8662)
                     /locus_tag="VYR58_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HEV3622768.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            8682..9047
                     /locus_tag="VYR58_001647"
                     /pseudo
     CDS             8682..9047
                     /locus_tag="VYR58_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(9267..9446)
                     /locus_tag="VYR58_001648"
     CDS             complement(9267..9446)
                     /locus_tag="VYR58_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622769.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(9588..9737)
                     /locus_tag="VYR58_001649"
     CDS             complement(9588..9737)
                     /locus_tag="VYR58_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622770.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            10042..10485
                     /locus_tag="VYR58_001650"
     CDS             10042..10485
                     /locus_tag="VYR58_001650"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV3622771.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            10487..11002
                     /locus_tag="VYR58_001651"
     CDS             10487..11002
                     /locus_tag="VYR58_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV3622772.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            11016..12377
                     /gene="radA"
                     /locus_tag="VYR58_001652"
     CDS             11016..12377
                     /gene="radA"
                     /locus_tag="VYR58_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV3622773.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            12450..12947
                     /locus_tag="VYR58_001653"
     CDS             12450..12947
                     /locus_tag="VYR58_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV3622774.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            12972..13755
                     /locus_tag="VYR58_001654"
                     /pseudo
     CDS             12972..13755
                     /locus_tag="VYR58_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            13900..14868
                     /locus_tag="VYR58_001655"
     CDS             13900..14868
                     /locus_tag="VYR58_001655"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV3622775.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVAVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(15002..15283)
                     /locus_tag="VYR58_001656"
                     /pseudo
     CDS             complement(15002..15283)
                     /locus_tag="VYR58_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15410..15600)
                     /locus_tag="VYR58_001657"
                     /pseudo
     CDS             complement(15410..15600)
                     /locus_tag="VYR58_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15611..15727)
                     /locus_tag="VYR58_001658"
     CDS             complement(15611..15727)
                     /locus_tag="VYR58_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV3622776.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(15942..16292)
                     /locus_tag="VYR58_001659"
     CDS             complement(15942..16292)
                     /locus_tag="VYR58_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV3622777.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDILAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            16548..19181
                     /gene="polA"
                     /locus_tag="VYR58_001660"
     CDS             16548..19181
                     /gene="polA"
                     /locus_tag="VYR58_001660"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV3622778.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEF
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            19266..19703
                     /locus_tag="VYR58_001661"
     CDS             19266..19703
                     /locus_tag="VYR58_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV3622779.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
BASE COUNT         5518 a         3346 c         4462 g         6488 t
ORIGIN      
        1 atatcaaaaa gaacctcaaa aaggtattac caagttgcaa taccttttac gaggctcttt
       61 tctcttgttc ttgtttcaat tgactatatt agaggcgaga catttttcgg ttctttgtca
      121 actgtagtgg gttgaagaaa gcgaagatct agaaaggaca aatttcgtcc tttctttttt
      181 gaagttttca aagttcctaa aaccaaaggc attgtgcttg ataagtttga tgagattatt
      241 ggtggcttcc agtttggcgt tggaataagg taattgaagg gcgttgacga ttttctcttt
      301 atctttgagg aaggttttaa acaaagtctg aaacagaggt ggaaaagcaa gagctgatag
      361 agattatagt ggtgtttcaa gtcttcggaa tagctcaaaa gtttatctag aatttcttta
      421 ttagtcaagt gcatacgaaa agtagggcga taaaatcgtt tatcactcag tttctgacta
      481 tcttgttgaa tgagcttcca gtagcgcttg atagccttgt attcatggga tttcggatga
      541 tggcttgtgt tctgctctca agaacagtta tgatattgag tttatcaaag tcctgagcaa
      601 taaagctcat ctccatctcc cgattgaaac agtcactccc cggactgttt caacgtccta
      661 ggacataatc tcaggaagac gcgaaaaatc atgctcaaag tgaaaattat tgatcttgcg
      721 aatgacagtt gaagttgaaa tagacaactg atgatcaatg tcggtcatag aaatcttttc
      781 aattaacttt tgagcaatct tttggttgat gatacaagga atttgatgat tcttcttgac
      841 gatagaagtc tcagcgagct ccatttttga gcaatgatag cacttaaaac ggccttttct
      901 aagaagaatt ctagtttgaa tttttttata ctagaaaatc agaaccataa tacctatata
      961 aaaatattat agttctaata ggatttaccc aaaagtttta aggcggtctt tttagaactt
     1021 taattgtttg aaatttaggt agcaaatttg tttctatttt gtcaactttt cctattttta
     1081 tcttgttgag gctggtattt taacaattca ggaattgata gtgaatgtgt aaaatttttt
     1141 gttagaataa gtttataaaa aagaaaagga gtatttgatt atgttacaaa aaatttatga
     1201 gcagatggct aatttctatg atagtattga agaagagtat ggtcctacat ttggtgataa
     1261 ttttgactgg gaacatgttc attttaaatt tttaatttat tatttagtga gatatggcat
     1321 tggttgtcat agggatttta tcgtttacca ttatcgtgtt gcttatcgtt tgtatcttga
     1381 aaaattggta atgaatcggg gttttatttc ttgttgaggt aattttagta aatttccgaa
     1441 ctaatttact cttttatgta aagataatag taaatagcta gtaatttttc taaatcattt
     1501 tttaatagtt ggaaatagca aatctttcta ttgtttcttc ttgataaaaa ggcgattttt
     1561 tattataata aattgtaaga tataattgca ggtgagagtc ctgccatgta tgtgagaaag
     1621 gaagagcctg agggctcaga caaaattatg acttcagttg ttgttgtagg tacccaatgg
     1681 ggtgatgaag gtaaagggaa gattacagac ttcctttcag cgaatgcaga agtgattgca
     1741 cgttaccaag gtggtgataa tgctggtcac acgattgtga ttgacggtaa gaaatttaag
     1801 ttgcacttga ttccatctgg gattttcttc cctgaaaaaa tatctgtcat tgggaatggt
     1861 atggttgtaa atcctaaatc tcttgtaaaa gagttgagct atcttcatga ggaaggtgta
     1921 acaactgata acttgcgtat ttctgatcgt gcgcatgtta ttttgcctta tcatatcgag
     1981 ttggatcgct tgcaagaaga agctaagggc gacaataaga ttggtacgac aattaaggga
     2041 attggtccag cttatatgga caaggctgct cgtgttggaa ttcgtattgc agatctttta
     2101 gataaagata ttttccgtga gcgtttagaa cgtaaccttg ctgaaaagaa tcgtcttttt
     2161 gaaaaattgt atgacagtaa agcgattgtt ttcgatgata tttttgaaga atattacgaa
     2221 tatggtcaac aaatcaagaa atacgtgata gatacatctg ttatcttgaa tgatgcgctt
     2281 gataatggca aacgtgtgct ttttgaaggt gcacaaggtg ttatgctaga tatcgaccaa
     2341 ggtacttatc catttgttac gtcatcaaac cctgtagctg gtggtgtgac aattggttct
     2401 ggtgtcggtc caagcaagat tgacaaggtt gtaggtgtat gtaaagctta tacgagtcgt
     2461 gtaggagatg gtcctttccc aactgagttg tttgatgaag tgggagaacg tatccgtgaa
     2521 gtgggtcatg agtatggtac aacaactggt cgtccacgtc gtgtaggttg gtttgactca
     2581 gttgtgatgc gtcatagccg tcgtgtttct ggtattacta acctttcttt gaactctatt
     2641 gatgttttga gcggtttgga tactgtgaaa atctgtgtgg cctatgatct tgacggtcaa
     2701 cgtattgact actatccagc tagtcttgag caattgaaac gttgcaagcc tatctatgaa
     2761 gagttgccag gttggtcaga agatattacc ggagttcgca atttggaaga tcttcctgag
     2821 aatgcgcgta actatgttcg tcgtgtgagt gaattggttg gcgttcgtat ttctactttc
     2881 tcagtaggtc ctggtcgtga acaaacaaat attttagaaa gtgtttggtc ctaagagatt
     2941 tttaagattt gtttaagata ggtcgggtat actatagaca gttacaagaa gacctcctaa
     3001 cttgttgtaa caaatatcct aaacttttct ttttcataat aatctcccta tagagtcacc
     3061 gcattcggtg gcttcttttg tgttgggatt catgatataa taataaaatc gataagtagg
     3121 aaaagagaaa agagatgtat tatacgcttg aagaaaaaga agtctttatg agggaggctt
     3181 tgagagaggc tgagattgct cttgaacacg atgaaattcc aattggttgt gtgattgtca
     3241 aagatgggga aatcattggt cgtgggcata atgcgcgtga ggaattacag cgagcggtta
     3301 tgcatgcgga aattatggct atagaggatg cgaacttgag tgaggagagc tggcgcttgc
     3361 tggattgcac actttttgtg accattgaac cttgtgttat gtgtagtggg gcgattgggc
     3421 ttgcccgcat tccaaatgtg gtctatgggg ctaaaaacca gaaatttggc gctgctggga
     3481 gtttgtacga tatcttgaca gatgagcgtc tcaatcatcg tgtggaggtt gaaataggaa
     3541 ttttggaaga tgaatgcgca gctatcatgc aggatttttt tagaaataga cggaaaaaat
     3601 aattttgctt ttaaaatgaa taggaatgtg atataataaa tagtggagca acagttctgc
     3661 gtgaagcggg tcaggggagg aatccagcag ccctaagcga tttgaattgt gtgctctttt
     3721 ttcgtgcact ttaaaaaccc tttaaaatca acactttaag gggtttttgt ttgtcttgta
     3781 taagaaaaag gggcagacga ggggcacaat ttaaaatttt atcttgtcta acttgctaga
     3841 tatgtctgat accatttttt gagtaacgtg agaataaatc tctagtgtgg tctttgagtc
     3901 actatgccct actctgtcca tgatggcagt caagggaatg cccagctcag caagtaggga
     3961 tatgtgagaa tgtctaaatg tatgtgtagt tatgtttttt tctatgccga ttttttgacc
     4021 atgtcttttc aatgcacaaa taaccctggc atttgttatt ggttctccta gagtattgat
     4081 gaaaataaaa tctgtatcaa atccatttgt cgcattctct attatttgct ctttgataat
     4141 atctaacact ttttgaggtg ctgttataac cctatcggac ttgattgtct ttggtgtagt
     4201 tctctctttt tgtctgaaat cgtatgtatg cttgatgtga atagtctttt tagaaaaatc
     4261 tatatcttcc ttgtagttta aggctgccag ctctccatac ctcatgccag taagaaaaag
     4321 aactttagct attcggatat actttgtaat tcgataatca catagggcct cgtcttttaa
     4381 attttggatg aataacttaa actctttttg gtctaagtat tttgtatttt tctttctgag
     4441 ttcgtcggat gtaattactt ttctaggcgt ttcaacaaat agcatttcat ttgtatcaat
     4501 ataattcatt ctgatagcaa atttcattat ctgattgagc ttgaatttga ttttagaaac
     4561 atagttatga gatctcccat cttgtaatag ttgatctatt actttttgta ataaacgtct
     4621 atcaaatttc taactaggta gtcgccctct atctgcttta aaatctcttt ttttacattc
     4681 tttgaagcgt agacggttga gttttttacg ccgtgtttcc aattctcctc aaattcttca
     4741 tatagttttt caaaagttat attagaaaca gaatgttgtt tttctcctaa cttttgtttt
     4801 atcttttcct gaagtaaaat cgcagcttga tttcttgctt ggggagtttt tttctccatc
     4861 gttactgaga ctttttttaa tttctcagta tatggatctt tgtatctctc aaaaaattta
     4921 tatttgccgt ttggcaattc ttccatccac attgatttta cctcactttt ttgataaaat
     4981 gggtatagta aagagggctt tttttattat gagaatttct tgattacttc taaaatttca
     5041 ttggcataat ttgcgacttc gagaggggta gacaccggga agatgccttt atcacggatt
     5101 tcgatagtgc ttttttttga atttgaacga taacgtaata cccatttttt gatgttatcg
     5161 tcaaccaaaa cattgaaata gctacggtta tctctgtaaa atacacgttc tggagaaact
     5221 acatccctag caagcatttt aacaacagta taaacttcta attcagcagg agttgtgata
     5281 atttcgtcag ttacttcgac aatctcttca gcttcagctt caacttttgg aatatcggtt
     5341 gttactttgg tttcaacgct tgtattaagt gcagcactta atttttcatt aactcgctct
     5401 gtgatgaatt gattaaaccc tttcacaata atgggagaaa atgtcgttaa gatattttga
     5461 gtaacacgcc cttcatagat ttcagaagtt agatatctga ggaagctatc tgacggtgta
     5521 gtgatatttt cagtaaggaa cgctttaaga ttgttgaggt atttcaattc agaagctgat
     5581 gaaacaatat tatcaatatc aaaattctct ttgtggaatt tgatgatttc agtaaattga
     5641 ttttctttga tatcagtcac atcgattgtt aagaatggag ttgtgtccat tttatttggc
     5701 tcatctaaat cagtaaagaa tttatattct ctaccatttg tcaagatacc gaattttgat
     5761 ttagtagtta cgaaatatct gaatagttga gagtcgtgct tagtaaggtt ttctgtaatt
     5821 gatttacatt caattaggat ttgaggctcg ccatccaaaa tgatcgcata gtcgactttt
     5881 tcgccttttt taatgcccac gtcggcagta aattccggga caaattcaag tggattgaag
     5941 atatcatatc caagcgcttg gaagaacggc ataatgaagg cattctttgt ttgttcttca
     6001 ttcgtaatgc tttggctgag gtctgctaca cgtttgccga cttgttttaa atcggctttt
     6061 actttatcaa tttccatatt gatactcctt tttttaattt actaatgcta aatactcttc
     6121 tttaaccatg atttcatttg tcatggtttt tagattgtag taagacatga atttgaggta
     6181 atcaaactct gtggggtcgt ctaagttttc tagagcgtct tttacgagat gatggatcat
     6241 attcctatca gcttcgtttt cacagcgtag acgggcgttc tggtgctctg agcgtgtgtg
     6301 gtctttgtgt ccaagttcgt gtagggcgac ttggatttgt tgttcaggag tcaagttgtg
     6361 gtcaatagcg agcacgtttg tgtctggatt gtagaaaccg ctattgtgcc agtttgaacc
     6421 gtcgaagaga caaagttcta cttgatattc ttcgcagagt ttagcgagtg tcatagttct
     6481 ccttcgttat ttatagacat ctctgcggtg ggcgatttcc acggctagga cgactagttt
     6541 atcgtcttgg atatcacaga tgatgcggta attctctact ctgtatcgcc agtaacctgc
     6601 aaggttggct tttagtgctt ttccgtgttg tcgtggattg gtcgtgtttt caatgttttt
     6661 agcaagccag gataggattt gttttctggt tggggtatct agttttttaa gttgcttgag
     6721 agctttttta tcaatatcta gccgatacat taagcaatat cctctcgagt tagtcctagt
     6781 tcatccaaga cctcatccat ggtataagta gctgggtcgg ctaaatactc catataggct
     6841 tggtcggctg ctcgtgcgtc ttcgatatct tccatgagtg ccatgaagtc gtcaaaatcc
     6901 atggtcgttg tgtcgatacc gtgtttgttt aggtagtccg taatgtagga atttttttct
     6961 gtgaagttga tagtgatagt cattagcgtt ctcctttgct tttgaagtgg gcggatagga
     7021 cggatgtaat gaagtcgata tcatcttcat ttagtggttt cccgtcaaat aacatggtgt
     7081 tggctgctgc tttgcgtaag tctatgattt gtccgtttac ttgggcaaat tcatcactcc
     7141 cagcgatagc agggttatct gttcgtccga gcaggtagtc ggtggatacg ttgaaataat
     7201 tagcaatttc tgcgatacgt tcagcgtttg gcgtagaatt ttttatctta tagagtgtat
     7261 ttctaccata acctaagtct tcttctactt gtccaagagc ttttccacgc ttttttgcca
     7321 attcttttat tttttcaaat gtctcaaaca ttgttaaatc aacctttcta agacatcaca
     7381 aaaaaaattt aacaaatttg gtgtaaaaag gttgactaat tatcccaaaa ggtgtaaaat
     7441 gttttttgta agtgataaac aactaaaaaa acaactaaga aataaattat aaaaatgttt
     7501 tggcgaacgg tatttataga tttattggtg tttttattat gctttaattt tagccgattt
     7561 ggtgtaagtt gtcaagtata atgcagaaaa atagttacat ttttagttgt ttcttattta
     7621 caaataagta aagaggagga acgtgctgat ggtaagtatt cttaaaaatt tagaacaaga
     7681 aaaagaccac cttgaaaaag tcattaaggt agtcagcgct ggtggtaaat ttctgagatt
     7741 gccatatcaa aaaagtcacg ctcgattagt gagaatctga aattgatttc tcaaaatctt
     7801 taccatcatc gtagatgtcg cgtttgcttg ctttgagtaa atattcttta aaagtcataa
     7861 ggttaactcc tttctgctta tattatagca gaaaaagaag aaagaaaaag aaaggagaaa
     7921 atatgccaga tatcgcaaac ggtcgcgaaa gagttattgc tttcttgaaa gagaaaggca
     7981 ttaaaaaagc aactctagcg gttgcttacg gctttaaacg acaggaagtg acaaacattc
     8041 taagtggaac gactaaaggt ccacgagcga acagtttcat tcttcaggtt attgaagatt
     8101 atgggattga gtaggaaaga tttgaggagt aggaaaatga gaccaaaacg atatccgtat
     8161 agtggacaaa aagagtccac ctttgtaaag gcagaccctg agttagttga aaaactttta
     8221 agaaacacta gttttcttga gtgtttacaa aaaaagccta tcaattttca gatagactca
     8281 gaagaattta agcgtcttag ctatgaagcc attcatgata cttctcaagt aactcaatag
     8341 gaggaaggaa taaaatgatt caccattata taactcacta tgccagcaat gggaaagatt
     8401 acgccgaagc atggattcaa attgattttt tgggaatgtg cttttgtgta tggaaaaagc
     8461 gtacaaccat tgaacgattg tacgcaaacg aagattagac ttttttccaa ccgttgcctt
     8521 tagcagatgt cggagggagc cgatcacctt ttccgatagt tgcggtatga ccattagtaa
     8581 cttttccgcc acgaggtcct acctctacat agcgaccagg tttctgatta tctgttccag
     8641 gttttattgg agtatttgcc atactatctc ctcctttcta taagtttgag aaaatcaacg
     8701 gtatctggta ttatttcgat ggctcaggct atatgctttc agaccgctgg aagaagcaca
     8761 cagacggtaa ttggtactac tttgaccaat caggcgaaat ggccacaggc tggaagaaaa
     8821 tcgctgacaa gtggtactat tttgatgtag aaggtgccat gaagacaggc tgggtcaagt
     8881 acaaggacac ttggtactac ttagacgcta aagaaggcgc catggtatca aatgccttta
     8941 tccagtcagc ggacggaaca ggctggtact acctcaaacc agacggaaca ctggcagaca
     9001 agccagagtt cacagtagag ccagatggct tgattacagt taaataaata gaaaggaaac
     9061 tttctaaatt gttctttcac cgcaggctca ggcttgcggt tttttatttg ctctgattct
     9121 tcaaaaaagc gttttcttga agaataggga ggaggaatgg cagggtatta ttgccaaaaa
     9181 cgccattttg ttaataatag ctccttttta ttttttgatt attgtcaaaa acggtgtttt
     9241 gtcaaaaata aaaacagtga ccgaaatcac tgcttatcag ttgtagcaaa ttcataaagt
     9301 ttttctgctg tgagaagtgc cattttgtcc atgcttgttt ttccttttct gaggtcagaa
     9361 acagtagtcc atggaactcc agcaccttgg gaaatagcag atgtagacat cgaactgtct
     9421 aacaattctt gaataacttc tctcatctta tttgtccttt ttatttttta gataaatata
     9481 tacattgacc gcaattataa aaatagctat tgcactaacc attgcttttc ctcttttcat
     9541 ttgataaaat agaggtgtga ggggctttcg ccccaacctc ttagcgttca cctttttctt
     9601 tgacgggatt tcggtttacg ctttttgttt tgccttgcga ccgttattgc agtcaccaga
     9661 cttgctatag cagttaccgt ttcagggata ttatctatcg ccttttccag taacctaagc
     9721 caatcttctt tgttcaactt cctcacctcc tttccttatc ttgattatat tatatcacgg
     9781 taaaccgtga aagtcaagcg atttgatgaa gtttttttga aaaacaaagg ggcaaaaaag
     9841 gggcaaaagt gtcgtaaacc tctgtaaaac gatgtaaaaa atcaactttg ccctcgcttt
     9901 aaagctctaa atttcaacgt attgtgaaac agtgtaaatt atcgtatcgc ctataattgt
     9961 tgtgtgctct ttttttcgtg ctttttccga ataaataaga tagaataatc tagaataaat
    10021 gataatagaa aagagaaaat tatgaaaatt cgtggttttg aattggtttc gagttttaca
    10081 gatgaaaatt tattgcccaa gcgtgagaca gcgcatgcgg ctggttacga cttaaaggtt
    10141 gctgtgcgta cagttgttgc gccaggagag attgtcttgg ttccgacagg ggttaaggct
    10201 tatatgcagc cgactgaggt tctctacctc tatgatcgtt cttcaaatcc tcgtaagaag
    10261 ggcttggttt taattaactc agttggggtc attgatgggg attattatgg aaatcctgga
    10321 aatgaagggc atatttttgc gcagatgaag aatatcacag atcaagaggt tgttcttgaa
    10381 gttggggaac gtattgtcca ggctgttttt gctactttct taattgcaga tggagatgca
    10441 gctgatggcg ttcgaactgg tggatttgga tcgacagggc actagaatga agattatctt
    10501 tgtacgtcat ggggagccag attaccgtga gttagaggag cgttcttata taggatttgg
    10561 gatagatttg gcacccttgt ctgagatggg acggcagcaa gtccagaaat tgagcaaaaa
    10621 tcctttactc tcgtcagctg aaataatcgt atcttctgca gtcacaagag ctttagaaac
    10681 ggcttcgtat gtggtctgtg ctacgggtct tcctttaaga gtagagcctt tattacatga
    10741 atggcaggtc tataaaacag gaatagaaaa ctttgaaaca gctagaagac tgtttttaga
    10801 aaacaagggg gagttgcttc ctaatagtcc tattcaatat gagacagcta cggaaatgaa
    10861 gtctcggttt ctagaatgta tgtctaagta tcgagaacat cagactgtgg tagttgttgc
    10921 tcatcgaatg ctcatgcgcc agtttgtgcc aaatgagaag attgattttt gccaagtgat
    10981 tgagtgtgag ttagagatat agaaagaggt ttgtcatcgc aaagaaaaaa gcgacatttg
    11041 tatgtcaaaa ttgtgggtat aattccccta aatatctggg acgttgcccc aactgtgggt
    11101 cttggtcttc ttttgtggaa gaggttgagg ttgccgaggt caagaatgcg cgtgtgtcct
    11161 tgacaggtga gaaaaccaag cccatgaaac tagctgaggt gacttccatc aatgtcaatc
    11221 gaaccaagac ggagatggag gaattcaacc gtgtgcttgg aggcggagtg gtaccaggaa
    11281 gtctcgtcct catcggtggg gatcctggga ttgggaaatc aactcttctc ctacaagtct
    11341 caacccagtt gtcccaagtg gggacagttc tctatgtcag tggggaggag tctgcccagc
    11401 agattaaact acgtgcagag cgcttaggtg atattgatag tgagttttat ctctatgcag
    11461 agaccaatat gcagagtgtt cgtgcagaag tggagcgtat ccagccagac tttctcatta
    11521 ttgattccat ccagaccatc atgtctcctg agatttcagg ggtgcagggg tctgtttctc
    11581 aggtacgtga agtgaccgct gaactcatgc agttggccaa gaccaataac attgccatct
    11641 ttatcgtagg tcatgtgacc aaagaaggaa ccttggctgg gcctcgtatg ttggagcata
    11701 tggtggatac ggtgctttac tttgaagggg agcgtcacca cacctttcgt attttgagag
    11761 cggtcaaaaa tcgttttggt tccactaatg agattgggat ttttgagatg cagtcgggcg
    11821 gcttggttga ggtactcaat ccgagtcaag ttttcctaga agagcgtttg gatggggcga
    11881 ctggttcctc catcgttgta accatggaag ggacgcgtcc gattttggcg gaggttcagg
    11941 ctttggtaac accgaccatg tttggaaatg ccaagcgtac tacgacagga cttgatttta
    12001 accgtgctag cttgattatg gctgttttgg aaaaacgggc agggcttctc ttgcaaaatc
    12061 aggatgccta tctcaaatct gctggtggtg ttaaattgga tgaacctgcc attgacttgg
    12121 ctgttgcagt tgctattgct tcgagctaca aagacaagcc aactaatcct caggaatgtt
    12181 ttgtcggaga actgggcttg acaggagaga ttcggcgcgt gaatcgtatt gagcaacgca
    12241 tcaacgaagc tgctaaactg ggctttacta agatttatgt acctcagaat tccttgacag
    12301 gaatcactct gcctaaggaa attcaggtca ttggcgtgac aacgattcag gaagtcttga
    12361 aaaaggtctt tgcataatcc gtgacaaatt ctcttaaaaa tgataagata ggagaaatat
    12421 ttgactatca aattttcaag gagggaatcg tgtcgtattt tgaacagttt atgcaagcca
    12481 atcaggctta tgttgcccta catgggcagt taaatctgcc acttaaacct aaaaccagag
    12541 tagccattgt gacctgtatg gactcacgtt tgcacgttgc gcaagctctg ggcttggcac
    12601 ttggggatgc tcatatcttg cggaatgcag gtggtcgagt gactgaagac atgattcgtt
    12661 cgctagttat ttcccagcaa caaatgggga caagagagat tgtggtattg caccatacag
    12721 actgtggtgc tcagaccttt gaaaatgaac cttttcagga gtatttaaaa gaggaattag
    12781 gtgtagatgt gtcagaccag gacttcttgc ccttccaaga tatagaagag agtgtacgcg
    12841 aggatatgca actgcttatc gagtctcccc taataccaga cgatgtcatt atctctggtg
    12901 ctatttacaa tgttgataca ggaagtatga cagtcgtaga attataaata cttcatttag
    12961 aaagaaagtg tatgaagaaa agcagtattt tatttatttt tattttattg ctatgtattg
    13021 gtttacagta tgaaaccatc tactatacgg acggttcgag gtcaggtgcg gaatatggac
    13081 taatgggagt ttctatcttt ctagctctct tttacatgat tccggctctt tattttctct
    13141 tccgtattgg gaaaaaatgg gaattgccaa agaaggtttt gattctgtct ttattgggag
    13201 ggatgttcct ttcaggctgg ttgtctagtt ttgctaatac ttatatacat gatttactgg
    13261 gggttctttt cccagatagt ccatttttaa atgcctttga aagtgctatt gtggctcctt
    13321 tggtagaaga acccttgaaa ttattgccac ttgtttttgt tttggctttg attcctgtgc
    13381 gaaaattaaa atttttgttt ttacttggaa ttgcctccgg tttgggattc caaatgattg
    13441 aggatattgg ttatattcgt acggatttgc cagagggctt tgactttact atttcgcgaa
    13501 ttttagagcg tatcatctca ggaattgcct ctcactggac tttttcaggt ctagctgtag
    13561 taggtgttta cttgctttac agagcctata aaggacagaa ggttggcaag aaacagggtc
    13621 ttattgttta actctccttt tgtggagttg gaaacagagt tgcctttagc gattccagtg
    13681 gttacggcta ttgctctcta tggttattat catgcttatt gctttgttga gaaacacaat
    13741 gagttgatga cctagaatat ttttcaaaag aatgatgcaa gggtacaaat atggtgccct
    13801 tcttttattt ttgattgaaa aatagtgcaa aaagcgctac aatggtagat ggaaaatctt
    13861 gtgaaaagca caagcgatac atatataccg gaggaaatca tgtctttttc tgatttaaag
    13921 ctgtttgccc tttcttctaa taaagaattg gcagaacgtg tggcgcagga gattgggata
    13981 gagttgggga aatcaagtgt tcgccaattt tcagatggag agattcaggt caacattgaa
    14041 gaatcaatcc gtgggaaaca cgtctttatc ttacaatcaa ctagttcgcc tgtaaatgac
    14101 aatctgcttg aaattttgat tatggtagat gctttgaagc gtgcgagtgc agagtctgtc
    14161 aatgttgtca tgccttacta tgggtatgca cgtcaggata gaaaggcgag agcgcgtgag
    14221 ccaatcactt caaaacttgt cgcaaatatg cttgaagtag ctggagtgga tcgtttattg
    14281 accatcgact tgcatgctgc gcaaattcaa ggattctttg atattcctgt ggatcatttg
    14341 atgggtgctc ctctaattgc agattatttt gagcggcgtg gtatggttgg ttctgactat
    14401 gtggttgtca gcccggacca tggaggggtg actcgtgctc gtaagttggc agaatttttg
    14461 aaaacatcta tcgctattat tgataaacgt cgtagcgttg ataagatgaa tactagtgaa
    14521 gttatgaaca tcatcggtaa ggttgaaggc aagacttgta tcttgattga tgatatgatt
    14581 gataccgctg gaacgatttg tcatgcggca gatgctcttg cggaagctgg tgctgttgca
    14641 gtctatgcaa gctgtacgca cccagttctt tctggtcctg ctacggacaa tatccaaaaa
    14701 tcagctatta agaaattggt tgttttggat accatctatc ttccagaaga gcgtttgatt
    14761 gataagattg agcagatttc aatcgctcat ctcctagggg atgctatcgt acgtattcat
    14821 gaaaaacgac cactttctcc acttttcgat attgagaaaa aaatttaatg accaagcctg
    14881 agatgattct caggtttttt cgtctttttt ccgaataaat agatagtagc ggtgaatcta
    14941 gtaaagctag atttaaaact gtgatataat aaaaagagaa gaaatatgac tgtacgtcat
    15001 cagaagtttc agcgaccatc atttttgaac agtgataaca cttgaatcga cgctttctaa
    15061 ggagaattct agtaggcata ccagtcgttt caagataagg aattttagaa ggtttttgaa
    15121 agtcatattt cttcaattgg tttccgcact cagggcaaga tggggcgtcg tagtccagtt
    15181 tggcgatgat ttccttgtgt gtatccttat tgatgatgtt taaaatctgg acattagggt
    15241 ctttaatgtc tagtaatttt gtgataaaat gtaattgttc catatgattc tttctaatga
    15301 gttgttttgt cgcttttcat tataggtcat atgggacttt ttttctacac aaaataggct
    15361 ccataatatc cataggggat ttacccacta tggatattat ggagccattt tacaacagtg
    15421 cctcaaattc agatactgac atacctaatt gctggctggc aacctcagaa gtcagaagac
    15481 cttggcgtac tatgtctagg aaggcaaaaa gtttcctttc ttcccttcct tcaactttcc
    15541 cacgctctag tccttgttca aggcatagtc ctgtgctaac aagacttgtt cttctcgcat
    15601 atgtagttga ctaaacattt tcctgtcctc ctcggaccag ctcttgtagt ccagcagttg
    15661 atttgcttgg gtaatggctc gttgcggttg ctgggtaaag ggcttgttgc cgaaaaactc
    15721 caaccatggc ttgcgaacct tgtctttgct ggtttctctg tattttttaa ttccaagaat
    15781 gccatcttaa ccagatggtt ttcctgtcca ttgttggtaa tcgccaatac ctcacctgtt
    15841 gtgtcttcgc gcatactaaa gctatgaaaa gccaggtcat ctgagaaata attactatcc
    15901 acgatagcaa tgacgtaaac aggagcgatg tgtttgtagc tctagtgagt atcaccttct
    15961 cgctgacgaa ttttttcaag attttgatta acctgactgc acaggtaagt ccacaagtga
    16021 ttgatgaaaa aattctgatg atggacttga atctcaataa ttacttgagt accgttatcc
    16081 aactccgcca agatgtctat actggtataa aaatcctgca ccgagtaagg catggagagt
    16141 aatacgtgaa tatcgcttcc ctccaaaatg gtcacatttt ttgctggcaa gtccagcata
    16201 tcgcgaataa attgacaagt gatttctgga ttgctgaata ttttcttagc aatcaaatca
    16261 ttagttgggc tgatgcccgg atgtctgaga atcctcctat tcctccttct atagtgagtt
    16321 gaaataagat gtgaataact ctatcaggaa agtcaaatta atttatagaa atattttagc
    16381 agtcaaggtg tactattata gattcaatat actatattat agcacatttt taaatctagg
    16441 tttactaaat tctctggctc tatctattta ttcggaaaaa gtttgaaaaa tacttgctct
    16501 agctcttccc aatggtattt tttgattctt tcctttataa tgggtgtatg gataagaaaa
    16561 aattattatt gattgatggg tcttctgtag cttttcgggc gttttttgcg ctgtatcagc
    16621 agttggaccg ttttaagaat gcggctggtt tgcataccaa tgcgatttat ggttttcagt
    16681 tgatgttgag tcatttgttg gagcgggttg agccgagtca tattttggtg gcttttgatg
    16741 cgggaaagac gaccttccgg acagagatgt atgcggacta taagggtggt cgggccaaga
    16801 ctcctgatga gtttcgtgag caatttcctt tcattcgtga gttgctggat catatgggga
    16861 ttcgtcacta tgagctggct cagtatgagg cggatgacat cattgggacg ctggataagc
    16921 tagcagagca ggatggtttt gatattacca ttgtcagtgg ggacaaggat ttgattcagc
    16981 tgacggatga gcatacggtg gttgaaattt ccaagaaagg tgtggctgag tttgaggcct
    17041 ttacgccaga ttacctcatg gaagaaatgg gcctcacacc agctcagttt atcgatctca
    17101 aggcgctcat gggtgataag tcggataata tccctggggt gaccaaagtc ggtgaaaaga
    17161 cgggtattaa gctcttgctg gagcatggtt cgcttgaggg gatttatgaa aatattgatg
    17221 gaatgaagac ttctaagatg aaggaaaatc tcatcaatga caaggaacag gcctttttgt
    17281 ctaaaacact agcgaccatt gataccaagg caccgattgc gattggttta gaggacttgg
    17341 tctatagtgg tccagatgtt gaaaatcttg ggaaattcta tgatgagatg ggcttcaaac
    17401 agctcaagca ggctttaaat gtgtcgtcag ctgatgtgtc tgagagtttg gattttacta
    17461 ttgttgacca aatcagtcaa gatatgctga gtgaagagtc tatcttccac tttgagcttt
    17521 ttggtgagaa ttaccatacg gataatttgg ttggatttgc ctggtcttgt ggggataagc
    17581 tctatgccac agacaagctt gagctgttgc aagacccgat tttcaaggat ttcttagaaa
    17641 aaacatctct gagagtttat gactttaaga aggttaaagt tcttttgcaa cgttttggtg
    17701 tggatttgca ggcgcctgct tttgatatcc gtttggctaa atacctcctt tcgactgtgg
    17761 aggacaatga aattgcgacc atcgctagtc tttatggtca gacttacttg gttgatgatg
    17821 aaactttcta cggtaagggt gttaaaaagg ccattcctga acgtgagaaa ttcttggaac
    17881 acttagcttg taaacttgct gttttggtag aaacagagcc tattttactt gaaaaactca
    17941 gcgaaaatgg gcaattagag cttctttatg atatggagca acctctggct tttgtccttg
    18001 ccaagatgga aattgctggg attatggtca agaaagagac cttgcttgag atgcaggctg
    18061 aaaatgagtt tgtcattgaa aaactgactc aagagattta cgagctggcc ggtgaggagt
    18121 ttaatgtcaa ctcgcctaag cagttgggcg tgcttctctt tgagaaattg ggacttcctc
    18181 tagaatacac taagaaaacc aagacaggtt attcgacagc agtggatgtt ttggagcgtc
    18241 tcgctcctat tgctccgatt gttaagaaaa tcctggatta ccgtcaaatt gctaagattc
    18301 aatctactta tgtaattggc ttgcaggact ggattttggc tgatggaaag attcatactc
    18361 gctatgtgca ggatttgacc cagaccgggc gtttgtctag tgtggatcca aacttgcaaa
    18421 atattcctgc ccgattggaa caagggcgct tgattcggaa ggcttttgtg ccagagtggg
    18481 aggatagtgt gctactcagc tctgattatt cacagattga attgcgcgtt ttggcgcata
    18541 tttctaagga tgagcacttg attaaggcct tccaagaggg ggcagatatc catacttcga
    18601 cagccatgcg ggtctttggc attgagcgtc ctgatgatgt gactgcaaac gaccgtcgca
    18661 atgccaaggc agttaacttt ggagtggttt atgggatttc agactttggc ttgtctaata
    18721 atttgggaat tagtcgtaag gaagccaaag cctacattga tacctacttt gaacgttttc
    18781 caggtattaa aaactacatg gatgaagtgg tgcgggaggc gcgtgataag agctatgtag
    18841 agaccctctt taagcgtcgc cgtgagttgc cagatatcaa ttcgcgcaac ttcaatattc
    18901 gtggttttgc ggagcgaact gctatcaact cacctatcca gggttcggca gcagatattc
    18961 tcaagattgc catgattcag ctggataaag ccttggttgc aggtggttat cagaccaaga
    19021 tgctgttaca agtgcacgat gaaatcgtcc ttgaagtgcc taaatctgaa ttggtagaga
    19081 tgaaaaaatt ggtgaaacaa accatggaag aagccattca actcagtgtt cctcttatcg
    19141 cagatgagaa tgaaggggca acctggtacg aggctaaata aaaagggggc tagtcctcct
    19201 tttttgtagt agaattctgc aaaccttttc aaaatgtgct atactgatga aaaaggagga
    19261 tttctatgag tcaagaattt atcaatccaa gtgatggcgt gattcgtcag tatctcgcaa
    19321 cgagtaaaac ccttgctgtg gtgggtttgt ctgaccgtga agaaacaacc agcaatcgag
    19381 taacaaagga aatgcaggct cggggctata aaatcatccc agtcaatccc aaggcggcag
    19441 gtggcgaaat cttgggtgaa aaggcttatg ctagcctcgc tgaaattcct tttcctgtag
    19501 atattgtcaa tgtttatcgt cgcagtgaat ttctgcccga tgtggcgcgt gattttctca
    19561 aagctgatgc caagattttt tgggcacagc taggacttga aagtttagaa gcgaaagaga
    19621 ttttgcgtga tggtggatgt gatgatatcg tgatgaatcg ctgtatcaag agagaacata
    19681 ctcgcttgat tgaggaagca taagaaaaag gtagctgatg ggctaccttt tgtgttatac
    19741 tcaatgaaaa tcaaagagca aactaggaaa ctagctgcgg gttgctcaaa acactgtttt
    19801 gaggttgtag atac
//
LOCUS       DAVMJI010000036        18880 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.036, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000036 DAVMJI010000000
VERSION     DAVMJI010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18880
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.036"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            1..1983
                     /locus_tag="VYR58_001662"
     CDS             1..1983
                     /locus_tag="VYR58_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622780.1"
                     /translation="MKLKLCIIGFFFCLIATIGLVTISDTEIPIPLPIDGAFSIQGKS
                     NLSNNEIYEMVRDLSKTEKVTIYKPIVQSSGQLKYVNFDDVNNEQLKSAPIVGMYYTL
                     GKMDVDSLKPLTMTGLQTVYMAYPWYIGGILQFTGTLRILLMGSIYLTLLVVLFVVRT
                     RQIKEGVIRRSLGLPIYDLRREYGISLIFELIMMALLMISYSSFLGNGFFTYSSKLFF
                     SLLLTNFILFQIIDLITFVLFWLTIQIEKPIEIIKNKAKNKLIFVVWLAIISIIILVS
                     GVFLQETKSSQSSINIQIQNLVPWDTVKDWRRIEFLGIESNSTKNREVNDSDGQYLQI
                     VAALKNLDFLYIERSSAYVPDFMKTSHVIENFSKQLENDGITNPEINKELIYINQTGA
                     NLQNKVNGTNYHLLDNKIATIYIPEKWKENQKSIENTVVAEQFIGTNYTREQLAVQII
                     PDGEKIFYFNEDADNNLKMKDILPLANVADSKDNIVVVLDTDKMMENNKFSLASNILY
                     KSLFSPEAVKKINEMTVLLNFSMNPVDVYQIVKLKIQSLEHQILLSQILQKIIYSIVF
                     ILIYQYVQLFITLKQNEYVKKIILGLSKTYIAISSLKYFMMTITMVILFTFLMTGQIE
                     LLYIGAASLLVLMLSIIMSFRKLSESYTKILKGDES"
     gene            1980..2603
                     /locus_tag="VYR58_001663"
     CDS             1980..2603
                     /locus_tag="VYR58_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3622781.1"
                     /translation="MTIDLLNVSKSFGSKKIFTDLNLIFESGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGNVLVDKQDIWKIKERTFFKNTVGYVFQNYSLIDNKTVYDNLSLIT
                     KDKKTITDVLEKVGLSSDYLHQKIYELSGGQAQRVAIARMLMKPRKIILADEPTGALD
                     GEIGKEIIRLLLNETAEDKYVIIATHDPAVYNEVDVIIDMKDIGYKV"
     gene            2600..3100
                     /locus_tag="VYR58_001664"
     CDS             2600..3100
                     /locus_tag="VYR58_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622782.1"
                     /translation="MKKKIYIALIFVTGVLAIFFFGKQMITKENINKPTVELTIYTLS
                     SSDTEKWNKVRQVETEEAIYFITVKEVSSSEEVFSNIIANGAATGFGVREEEVKKFNN
                     GLGDTIEDSKHNKLIEIEFFTFSDDGAGFVVANFDYGKEELNSQKKDIKELYKKIYES
                     FKEKNK"
     gene            complement(3266..4612)
                     /gene="gor"
                     /locus_tag="VYR58_001665"
     CDS             complement(3266..4612)
                     /gene="gor"
                     /locus_tag="VYR58_001665"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV3622783.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            4877..6076
                     /locus_tag="VYR58_001666"
     CDS             4877..6076
                     /locus_tag="VYR58_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV3622784.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            6060..6761
                     /locus_tag="VYR58_001667"
     CDS             6060..6761
                     /locus_tag="VYR58_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622785.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            6763..8022
                     /locus_tag="VYR58_001668"
     CDS             6763..8022
                     /locus_tag="VYR58_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622786.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSSFTVSGKEEEIPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDISLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            8146..10143
                     /gene="metG"
                     /locus_tag="VYR58_001669"
     CDS             8146..10143
                     /gene="metG"
                     /locus_tag="VYR58_001669"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV3622787.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPEGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHAHMEAVDYPRALEAVWTLISRTNKYIDETAPWILAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            10187..10267
                     /locus_tag="VYR58_001670"
                     /pseudo
     CDS             10187..10267
                     /locus_tag="VYR58_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            10474..10794
                     /locus_tag="VYR58_001671"
     CDS             10474..10794
                     /locus_tag="VYR58_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV3622788.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            10798..11613
                     /locus_tag="VYR58_001672"
     CDS             10798..11613
                     /locus_tag="VYR58_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622789.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSIFTISLVIGIWNWKEAVFRPFIS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            11688..12614
                     /locus_tag="VYR58_001673"
     CDS             11688..12614
                     /locus_tag="VYR58_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV3622790.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDVLMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            12680..12946
                     /locus_tag="VYR58_001674"
     CDS             12680..12946
                     /locus_tag="VYR58_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV3622791.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            12939..13637
                     /locus_tag="VYR58_001675"
     CDS             12939..13637
                     /locus_tag="VYR58_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV3622792.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKSLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            13648..14127
                     /locus_tag="VYR58_001676"
     CDS             13648..14127
                     /locus_tag="VYR58_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV3622793.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQYRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            14135..14863
                     /locus_tag="VYR58_001677"
     CDS             14135..14863
                     /locus_tag="VYR58_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622794.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            14905..15774
                     /locus_tag="VYR58_001678"
     CDS             14905..15774
                     /locus_tag="VYR58_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV3622795.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLDKEVWYRFSELTNTEANCLAGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            15749..16189
                     /locus_tag="VYR58_001679"
     CDS             15749..16189
                     /locus_tag="VYR58_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV3622796.1"
                     /translation="MIPQEMWNKYKQINPSIGDEIDAWAFGVEPDLLGDLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            16312..18858
                     /locus_tag="VYR58_001680"
     CDS             16312..18858
                     /locus_tag="VYR58_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV3622797.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
BASE COUNT         5870 a         3223 c         4096 g         5691 t
ORIGIN      
        1 atgaaattaa aattatgtat cattggattc ttcttttgtt tgattgctac aattggtctg
       61 gtcactatta gtgataccga aatccccata cctttaccaa ttgatggagc tttttctatc
      121 caaggaaaaa gtaatctttc taataacgaa atatacgaaa tggttcgtga cttatcaaaa
      181 acggaaaagg ttaccattta caagccaatc gttcagagtt cgggtcagtt gaagtatgta
      241 aattttgatg atgtaaataa tgaacaatta aagtcagcac caatagtagg gatgtattac
      301 acacttggga aaatggatgt agacagtttg aaaccactta cgatgacggg actacaaaca
      361 gtctatatgg cttatccttg gtatatagga ggaatattac aattcactgg aactttaaga
      421 atactgttaa tgggttcaat ttatttaact ttattagttg ttttatttgt tgttaggacg
      481 aggcagatca aagaaggagt gatacgacgt tctttgggct tgcctatata cgacttaaga
      541 agagagtatg gcatttctct tatttttgaa ctgattatga tggctttatt gatgatttct
      601 tacagttctt ttttgggtaa tggtttcttc acctatagtt ctaagttatt tttctctctg
      661 cttttaacga attttatact atttcaaatc attgatctta ttacttttgt tttattttgg
      721 ttgacgattc agattgaaaa gcctattgaa attattaaaa acaaggcaaa aaacaagctt
      781 atttttgtcg tatggcttgc tattatttcg attatcatcc ttgtctcagg agttttttta
      841 caagaaacaa agagtagtca atctagtatt aacatacaga tacagaattt agtaccatgg
      901 gatacagtaa aagactggag aaggattgag ttccttggaa ttgaaagtaa ctctactaaa
      961 aatagagaag ttaatgattc agatggtcag tatctacaga tagttgctgc cttaaaaaac
     1021 ttagatttct tatatataga acggtcttca gcatatgttc cagatttcat gaaaacttca
     1081 catgttatag aaaatttttc taaacaatta gaaaatgacg ggataacgaa tccagaaata
     1141 aataaagagt taatttatat caaccaaaca ggtgctaacc tacaaaataa agtgaatgga
     1201 acaaactatc atcttttaga taataagata gcaaccatct atattcctga gaagtggaaa
     1261 gaaaaccaga aatctattga gaatacagtt gtagcagaac aatttattgg aacaaactat
     1321 acaagagaac agcttgcagt tcaaataatt cctgatgggg aaaaaatttt ttattttaat
     1381 gaggatgctg ataataatct taaaatgaaa gatattttac cgctggcaaa tgtagcagat
     1441 agcaaagata atatagttgt tgtgttagat acggacaaaa tgatggaaaa taataagttt
     1501 tctttggcta gtaacatact atataaatct ctttttagtc ctgaagcggt aaaaaaaata
     1561 aatgagatga ctgtcctgtt gaatttctca atgaatccag tagatgttta ccaaattgtg
     1621 aaattaaaga ttcaatcctt agagcaccaa attttacttt cacaaatctt gcagaagata
     1681 atttacagta ttgtctttat actcatttat caatatgtcc aactttttat tactctaaaa
     1741 cagaatgaat atgtgaaaaa aatcattttg ggtctgtcaa aaacatatat agcaatttca
     1801 agtctcaaat attttatgat gactattaca atggttattc tatttacatt tcttatgaca
     1861 gggcaaatag agttgctata tattggagcg gcttctctgc tagttttgat gttgtcaatc
     1921 ataatgagtt ttagaaaatt atctgaaagc tacactaaaa ttttaaaagg agatgaatca
     1981 tgacaattga ccttttgaac gtttcaaaaa gtttcggctc aaagaagatc tttacagact
     2041 taaatttaat atttgaatct ggaaaaagct atgcattgat tggaggttct ggctccggta
     2101 aaagtaccct tcttaatatt ataggaagat tagaaaaaat tgacagtggg aatgttttag
     2161 ttgataaaca agatatttgg aagataaaag aaagaacttt ttttaaaaat actgttggat
     2221 atgtatttca gaattattct ttaatagata acaaaacagt gtatgataat ctgagcctta
     2281 tcactaaaga caaaaaaaca ataactgacg tacttgaaaa agtaggactg tcaagtgact
     2341 atttacacca aaaaatatat gaattgtctg gagggcaggc tcaacgtgta gctattgcca
     2401 gaatgttaat gaaaccacgt aaaattatct tagcagatga acctacagga gctttagatg
     2461 gtgagattgg aaaagaaatt attcgtttac tattgaatga aacagctgaa gataaatatg
     2521 tcattatagc gacacatgat ccagctgtct ataacgaagt tgatgtgata attgacatga
     2581 aagatatagg gtataaggta tgaaaaagaa aatttatatt gctttgatct ttgtaactgg
     2641 ggtactcgcc attttctttt ttggaaaaca aatgattaca aaagaaaata tcaataagcc
     2701 aacggtagag ttaacaatct atacgctttc ttctagtgat acagaaaaat ggaataaagt
     2761 gagacaagta gaaacggaag aagctatata cttcataact gtaaaagaag tatcatcttc
     2821 agaagaagta ttttcaaaca tcattgcaaa tggagctgct acggggttcg gagttcgtga
     2881 agaagaagtg aagaaattca ataatggttt aggagacacc atagaggact ctaagcataa
     2941 taaactaatt gaaatagaat tttttacttt ttctgatgat ggcgcgggat ttgtggtagc
     3001 aaactttgac tacggtaaag aagagttgaa ttctcagaaa aaagatataa aagaattata
     3061 taaaaaaata tatgaatctt ttaaagaaaa gaataaatga ttgtattata atccttgtat
     3121 tttgctatgg tttgttaatt gatttttgca tatcttactt caacatacta taaaataaaa
     3181 cataagaaaa cgagtatctc caactacgga aatactcgct ttttgatatt tagaagtgtt
     3241 ttttgctttg cttcttttgt ttcgattaac gcatggttac aaattcttca gatgcagttg
     3301 ggtgaattgc cacagttgca tcaaagtcag ccttggttgc tcccattttg atagcaacgg
     3361 caaatccttg aatcatttca tcaacgccgt agccaattcc atgaagtccg acaacttttt
     3421 cttctgaacc agctgttatg agtttgaaac gggattcttg acggttgcga gtgcaagcag
     3481 agtacataga tgcaaagctt gatttataaa ccttgatttg gtcttgaccg tattctttaa
     3541 tagcttgctc ttctgtcaaa ccaacagttc cgatagcagg gtgtgaaaag acaacagttg
     3601 gaatagttga gtaatccatt tttgcagtag tttttccgtt aaagagacgt tcagataggg
     3661 tacgtccggc cttgattgca actggagtca gttctttctc gcccgttaca tcacctagag
     3721 catagattcc ctcaacaaca gtattttggt attcatccac ttggataaag ccacgttcgt
     3781 tcagagtcac tccagctttt tcaagttgca agcccttaac gtttggacgg cgacctgtag
     3841 cccagataac ttggctagct gtgtgactag taccatcttc gaaatgaatg gtaatgccgt
     3901 cagtagtttt ttctaacttg acagggactt tgtgagtgtg aagtggtaag tttgttcttt
     3961 ccatttcctt gaccaaacct tcaacgatgt aggaatcaaa accacgtaaa ggacgatcgc
     4021 ggcgaacaaa gagatctgtc ttgacaccaa aagtgtggag tacgccagct aattcaacgg
     4081 cgatataacc agcgcctaga atggcaattg actctggaag ttcttcccag gcaaatacat
     4141 catcagaaga gccacctagc tcagcaccag gaatattagg aatacttgga tgggcacctg
     4201 tagcaatcac gatatgttta gcacgaatca gttcaccatt tacgcttaca gtatgagaat
     4261 ctacaaattc agcatgacct tcaatcaagt ctacaccgtt gcgtttaaaa ctaccatcat
     4321 aagaagaacg agcgcgatca atgtaggctt cacgattgcg acgtagggtt gcaaagtcaa
     4381 agttaagatc agtagtctta aagccgtagt cttctccaaa ttgatggaaa gtctcagcga
     4441 tttgcgcccc gtaccacatg atttttttag gaacacaacc gacgttgaca caggttccac
     4501 ctaatttctt ttcctcaata acggctgctt tggctccatg ttcaccagca cggttcatgg
     4561 tagcgattcc tccgctacct ccaccgatag caatgatatc atattctctc attgaaaact
     4621 cctttgtaat cttttaaata gtagagcgtc ttttttgata gttatatttt attctttttt
     4681 tgatttgatt gcaaaaatct gctacgcaca aaaaattgca aaaaagcttg ccaaataagt
     4741 caagatagtg tattatatat ctagtacaat agaaaagcaa aattccgaac gattgtttaa
     4801 tcctgaactg tattgtttgc tggagggaaa tttggtataa tagcaaagta ttgtaaaaaa
     4861 gaaaaggagt ttcattatga agaaaaagaa tggtaaagct aaaaagtggc aactgtatgc
     4921 agcaatcggt gctgcgagtg tagttgtatt gggtgctggg gggattttac tctttagaca
     4981 accttctcag actgctctaa aagatgagcc tactcatctt gttgttgcca aggaaggaag
     5041 cgtggcctcc tctgttttat tgtcagggac agtaacagca aaaaatgaac aatatgttta
     5101 ttttgatgct agtaagggtg atttagatga aatccttgtt tctgtgggcg ataaggtcag
     5161 cgaagggcag gctttagtca agtacagtag ttcagaagcg caggcggcct atgattcagc
     5221 tagtagagca gtagctaagg cagatcgtca tatcaatgaa ctcaatcaag cacgaaatga
     5281 agccgcttca gctccggctc cacagttacc agcgccagta ggaggagaag atgcaacggt
     5341 gcaaagccca actccagtgg ctggaaattc tgttgcttct attgacgctc aattgggtga
     5401 tgcccgtgat gcgcgtgcag atgctgcagc gcaattaagc aaggctcaaa gtcaattgga
     5461 tgcaacaact gttctcagta ccctagaggg aactgtagtc gaagtcaata gcaatgtttc
     5521 taaatctcca acaggggcga gccaagttat ggttcatatt gtcagcaatg aaaatttaca
     5581 agtcaaggga gaattgtctg agtacaatct agccaacctt tctgtaggtc aagaagtaag
     5641 ctttacttct aaagtgtatc ctgataaaaa atggactggg aaattaagct atatttctga
     5701 ctatcctaaa aacaatggtg aagcagctag tccagcagcc gggaataata caggttctaa
     5761 atacccttat actattgatg tgacaggcga ggttggtgat ttgaaacagg gtttttctgt
     5821 caacattgag gttaaaagca aaactaaggc tattcttgtt cctgttagca gtctagtaat
     5881 ggatgatagt aaaaattatg tctggattgt ggatgaacaa caaaaggcta aaaaagttga
     5941 ggtttcattg ggaaatgctg acgcagaaaa tcaagaaatc acttctggtt taacgaatgg
     6001 tgctaaggtc atcagtaatc caacatcttc cttggaagaa ggaaaagagg tgaaggctga
     6061 tgaagcaact aattagtcta aaaaatatct tcagaagcta ccgtaatggt gaccaagaac
     6121 tgcaggttct caaaaatatc aatctagaag tgaatgaggg tgaatttgta gccatcatgg
     6181 gaccatctgg gtctggtaag tccactctga tgaatacgat tggcatgttg gatacaccaa
     6241 ccagtggaga atattatctt gaaggtcaag aagtggctgg gcttggtgaa aaacaactgg
     6301 ctaaggtccg taaccaacaa atcggttttg tctttcagca gttctttctt ctatcgaagc
     6361 tcaatgctct gcaaaatgta gaattgccct tgatttacgc aggagtttcg tcttcaaaac
     6421 gtcgcaagtt ggctgaggaa tatttagaca aggttgaatt gacagaacgt agtcaccatt
     6481 taccttcaga attatctggt ggtcaaaagc aacgtgtagc cattgcgcgt gccttggtaa
     6541 acaatccttc tattatccta gcggatgaac cgacaggagc cttggatacc aaaacaggta
     6601 accaaattat gcaattattg gttgatttga ataaagaagg aaaaaccatt atcatggtaa
     6661 cgcatgagcc tgagattgct gcctatgcta aacgtcagat tgtcattcgg gatggggtca
     6721 tttcgtctga cagtgctcag ttaggaaagg aggaaaacta agatgcagaa tctgaaattt
     6781 gccttttcat ctatcatggc tcacaagatg cgttctttgc ttactatgat tgggattatt
     6841 atcggtgttt catcagttgt tgtgattatg gctttgggtg attccctatc tcgtcaagtc
     6901 aataaagata tgactaaatc tcagaaaaat attagcgtct ttttctctcc taaaaaaagt
     6961 aaagatggtt cttttactca gaaacaatca tcttttacgg tttctggaaa ggaagaggaa
     7021 attcctgttg aaccgccaaa accgcaagaa tcctgggtcc aagaggcagc taaactgaag
     7081 ggagtggata gttactatgt aaccaattca acgaatgcca tcttgaccta tcaagataaa
     7141 aaggttgaga atgctaattt gacaggtgga aacagaactt acatggacgc tgttaagaat
     7201 gaaattattg caggtcgtag tctgagagag caagatttca aagagtttgc aagtgttatt
     7261 ttgctagatg aggaattgtc cattagttta tttgaatctc ctcaagaggc tattaacaag
     7321 gttgtagaag tcaatggatt tagttaccgg gtcattgggg tttatactag tccggaggct
     7381 aaaaggtcaa aaatatatgg gtttggtggc ttgcctatta ctaccaatat ctcccttgct
     7441 gcgaatttta atatagatga aatagctagt attgtctttc gagtgaatga tatcagttta
     7501 accccaactc tgggtccaga actggcacga aaaatgacag agcttgcagg cttacaacag
     7561 ggagaatacc aggtggcaga tgagtccgtt gtatttgcag aaattcaaca atcgtttagt
     7621 tttatgacga cgattattag ttccatcgca gggatttctc tctttgttgg aggaactggt
     7681 gtcatgaaca tcatgctggt ttcggtgaca gagcgcactc gtgagattgg tcttcgtaag
     7741 gctttgggcg caacacgtgc caatatttta attcagtttt tgattgaatc catgattttg
     7801 accttgttag gtggcttaat tggcttgaca attgcaagtg gtttaactgc cttagcaggt
     7861 ttgttactgc aaggtttaat agaaggtata gaagttggag tatcaatccc agttgcccta
     7921 tttagtcttg cagtttcggc tagtgttggt atgatttttg gagtcttgcc agccaacaag
     7981 gcatcgaaac ttgatccaat tgaagccctt cgttatgaat gagatcaaca agatggacac
     8041 tcgtctatct tgtttttgta tggatttccc tatcgaaatt cattaaaaat gtgatataat
     8101 gaagtgttag aaaaacaggt ttcatttgcc tggaaaggaa aaattatgtc tgaaaaaaat
     8161 ttttatatta caacgccgat ttactatcca tctgggaaac ttcatatcgg ttctgcctac
     8221 acaactatcg catgtgatgt cctagcacgt tacaaacgcc tgatgggcta cgatgtattt
     8281 tatctgacag gtcttgatga acatggtcag aaaatccagc agaaagcgga agaagctggt
     8341 attacacctc aagcctatgt tgatggaatg gcggttggag ttaaagaact ctggcaatta
     8401 ctagatatct catacgataa atttatccgt acaactgatg actaccatga aaaagttgtt
     8461 gcacaggtct ttgaacgctt acttgctcaa gatgatatct acttgggtga atactctggt
     8521 tggtattcag tatcagacga agaattcttt acagaaagcc agctggcaga agttttccgt
     8581 gatgaagctg gaaatgtgac tggtggtatt gctccatcag gtcatgaggt tgaatgggtt
     8641 tctgaagaat catacttcct tcgccttagc aaataccaag accgtttggt cgaatttttc
     8701 aaagctcatc ctgaatttat cacgccagag ggtcgcctta atgaaatgct acgcaacttc
     8761 atcgagccag gtttggaaga tttggcggta tctcgtacaa cctttacatg gggagtgcct
     8821 gtcccatcaa atccaaaaca cgttgtctac gtttggattg atgcccttct taactatgcg
     8881 acagctcttg gctacgctca agacgaacat ggtaactttg acaagttctg gaatggaaca
     8941 gtcttccata tggtaggaaa agacatcctt cgcttccact ctatctactg gccaatcctt
     9001 cttatgatgt tggatgttaa attacctgat cgtttgattg cccatggttg gtttgtcatg
     9061 aaagacggaa aaatgtctaa gtcaaaaggg aatgtcgttt accctgaaat gttggtagag
     9121 cgttatggac tagatccact tcgttactac ctcatgcgta accttccagt tggttcagac
     9181 ggaaccttta ctcctgaaga ctatgtcggc cgtatcaact atgaattggc taatgacctt
     9241 gggaacctcc ttaaccgtac ggtttccatg attaataagt actttgatgg acaaatccct
     9301 gcctatgtag aaggtgtgac tgaatttgac catgttcttg ctgaggttgc agaacaatca
     9361 atcgcagact tccatgcaca catggaagca gttgactatc cacgtgcgct tgaagcagtc
     9421 tggactctga tctctcgtac caataaatac atcgatgaga ccgcaccatg gatcttggcc
     9481 aaggatgaag ctcttcgtga ccaattggca agtgtcatga gccacttggc agccagcatt
     9541 cgtgtagttg ctcacttgat tgaaccattt atgatggaaa ctagtcgtgc agttttgact
     9601 caacttggtt tggaagaagt ttctagtctt gaaaacttga gtttggctga cttcccagca
     9661 gatgtgactg tagttgccaa aggaacacct atctttccac gtctaaatat ggaagaagaa
     9721 atcgcctata tcaaggaaca aatggaaggc aataaaccag cagtcgaaaa agaatggaat
     9781 ccggacgaag ttgagctcaa actaaacaag gatgaaatca agtttgaaga ctttgacaag
     9841 gttgaaatcc gtgtggcaga agtcaaagaa gtgtctaaag tagaaggttc agataagttg
     9901 cttcaattcc gcttggatgc tggtgatgga gaagatcgtc agattctttc aggaattgca
     9961 aaatactatc caaatgaaca agaattggtc ggcaagaaag ttcaaatcgt tgctaacctc
    10021 aaaccacgta aaatgatgaa aaaatatgtc agccagggta tgattctatc agctgaacat
    10081 gatggcaaat taacccttct cacagttgat ccagctgtac caaatggaag tgtgattggg
    10141 taaaagtaga caggactagt tcagactagt tctgtttttt tatttatact caatgaaaat
    10201 caaagagcaa actaggaagc tagccgcagg ttgctcaaag cactgctttg aggttgtaga
    10261 tgaaactgac gaagtcagct caaaacactg ttttgaggtt gtagatgaaa ctgacgaagt
    10321 cagtaaccat acatacggta gggcgacgct gacgtggttt gaagagattt tcgaagagta
    10381 ttaactatta tgctttacaa actagtgtag aagtaatata ctataggtga agttactagt
    10441 aggtattaca aaatagatta gaagggagaa gtgatgaaag aaactcagct attaaaaggt
    10501 gttcttgaag gttgtgtctt ggatatgatt ggtcaaaaag agcggtatgg ttatgagttg
    10561 gttcagactt tgcgagaggc tggatttgat actatcgttc caggaactat ttatcctttg
    10621 ttgcaaaagt tagaaaaaaa tcaatggata agaggcgaca tgcgcccgtc gccagatggt
    10681 ccagatcgga agtatttttc attaatgaaa gaaggagaag agcgtgtctc agtcttttgg
    10741 caacaatggg acgatttgag tcaaaaagta gaagggatta agaatggggg ttaaaccatg
    10801 aagaaaatga agtattacga agaaacaagc gctttgctac atgagttttc tgaggagaat
    10861 caaaagtatt ttgaggagtt gtgggaaagt tttaatcttg ctggatttct ctatgatgaa
    10921 gactatctca gagagcagat ctatttgatg atgctagatt tctcagaagc agaacgagat
    10981 ggcatgagtg cagaggatta tctaggtaag aatcctaaaa aaataatgaa agagattctc
    11041 aagggagcac ctcgcagttc tatcaaagag tcccttttga cgccaattct tgtcctggcg
    11101 gtattacgtt attatcaact actaagtgat ttttctaaag gtcctctctt aacagtcaat
    11161 ttgctcacat ttttagggca acttcttatt tttctgattg gatttggact tgtggccaca
    11221 attttacgaa gaagtttagt ccaagattct cctaaaatga aaattggcac ttacattgtt
    11281 gttgggacta tagttcttct agttgtttta ggatatgtag gaatggcaag cttcatacaa
    11341 gaaggagcct tttatattcc ggctccctgg gatagtttgt ctatctttac gatttcgcta
    11401 gttatcggta tttggaattg gaaagaagcg gtctttcgtc catttatcag tatgattatt
    11461 gcccatcttg tggtgggttc tctgctccgt tattatgagt ggatgggaat ttcaaatgtt
    11521 ttccttacaa aagttattcc tttagctgtc ctctttattg gaatctttgt cttgttccgt
    11581 gggtttaaga agataaaatg gagtgaagta tagtcaaaaa gtcgttgcaa agcggttttt
    11641 tgttataatg aagggaagaa tgttagaaat taaaggagaa aaatttgatg agatacataa
    11701 ctcttggtca agatgacaaa gaattatcag aaattgttct cggaatgatg agaataaaag
    11761 ataaatctgt aaaagaagtt gaagagcttg tagaaacagc actttctgtt ggaatcaatg
    11821 ccttcgactt ggctgatatt tatggtcgtg gtcgttgtga agaactgtta ggtcttgtcc
    11881 taaaaaatcg tccagattta agagaaaaga tgtggattca gtccaaatgt ggcattcgca
    11941 ttgaagaatt tacctatttt gatttttcta aggactatat tataaaatca gtagacggta
    12001 ttttgcaaag attgaagatt gatcatctag atagcttgct ccttcatcga ccagatgttt
    12061 tgatggaatc tgaccaagta gcagaagcct ttaatctcct ttataaacaa ggtaaagttc
    12121 gagattttgg agtttctaat caaaatccta tgatgatgga gttgcttaaa aaagatgtca
    12181 agcagccgtt agctgttaat cagctacaat tgagtgcggc ttttactcca ggatttgaat
    12241 cagcttttca tgttaatatg gaagatagtc aagcagctat gcgagatggc agcatttttg
    12301 aatattgcca attacacgat gtggtcattc aagcatggtc tgtcttacaa ttcgggtatt
    12361 ttaaagggaa ttttgttgga aatgagaaat ttcaagcttt aaatcaagta cttgatcgtt
    12421 tagctattaa atatggagta acctcttcaa ctattgccat ttcttggata ttgcgttatc
    12481 cagcaaaaat gcaggcagtc gtaggtacaa caaatcctaa gcacttgaga gaagttagcc
    12541 gagcggcaaa ctttagctta acaagaaaag aatggtatga aatttatctt gctgcaggga
    12601 ataatttgcc gtaagtagta gcaggtttga ataactcaca ttcaaaaagc cgtataaagc
    12661 ggttttttgc tataattaaa tgaagaatgt agaattaaag gagaaaaaca tgacatttga
    12721 agagatcctg cctgggttaa aggctaagag aaaatatgta cgaactggtt ggggaggtgc
    12781 ggaaaactat gtccaactct ttgataccat cgagcaaaat gggcttgcac ttgaaatgac
    12841 accttatttc ctaatcaacg tttctggcga aggagaaggt ttttccatgt ggagcccgac
    12901 agtttgtgat gttttggcaa cggattgggt agaagtgcat gactaaacgt gtactcatta
    12961 caggagtgag ttcagggatc ggattggctc aagctcgcct ctttttagag aagggctatc
    13021 aagtttatgg agttgaccaa ggtgaaaagt cactcttaga gggtgatttt cactttttac
    13081 agagagattt gaccttggac ttggaaccta tttttgactg gtgccctcag gtggatgttt
    13141 tgtgtaatac tgctggagtt ttggatgatt acaaaccact gttggaacaa acggcgcagg
    13201 acattcaaga gatttttgaa atcaactaca ttattccagt agagttgact cggtattatt
    13261 tgacacaaat gctggaaaat aaaaagggaa tcatcatcaa tatgtgttcc attgcttcta
    13321 gcctagcagg tggaggtggt cacgcctata cttcatccaa gcatgccttg gctggcttca
    13381 ccaagcagtt ggctctagac tatgctgaag ctgggattca ggtctttggt atcgctccag
    13441 gagcagtcaa gacagctatg accgctgcgg attttgaacc aggtggtttg gctgactggg
    13501 tggctagtga aaccccaatc aagcgctgga ttgagccaga ggaaatagca gagcttagtc
    13561 tttttttagc aagtggaaaa gcgagcgcca tgcaaggaca aatcttgaca atagatggtg
    13621 gctggtcttt gaagtaggag gagttggatg gaaatcaaaa aacactttgg agtctacgct
    13681 gtttgcttag aaaatgggaa gttactctgc attgaaaaaa cgagaggccc ttatcaatat
    13741 cggtatgatc tacctggagg cagtcagcaa cttggtgaag gactgacgga aacgctgact
    13801 agagaagtta tggaagagac gggatttact gttagaagct actctaatcc tcgaatctac
    13861 gatgttttcg ttagggaaga gttaaaaaat tttatggttc accatgtcat ggccttgtat
    13921 gatgttgaaa tgaatgagag tgcacctcaa gttacgactt cggaagctgt gtctgatggt
    13981 gcgaatgatt cacttggata tatttggatg gatattcaag agattacaga agaaaatgca
    14041 tcgccattag tcttgaaggt taagtctgaa ttattaggat ttccagaact ggacaagact
    14101 tcttacatga attggaaggt gaagtagagg gataatggaa ctatttaaaa catggaagaa
    14161 aaatatggtt ctctatggtc ttaaatctca aattggaact gtctaccgaa acaatgatag
    14221 gacaacaagc ttttatgatg ttgggaattt tctataccta gcaggggagt tggattccag
    14281 attttgggaa gattttgtta gaaaatatgg tttagattat aagattatta tttcagaaaa
    14341 tactaattgg caagattttc tgcatcgaaa agtggggcta aattctttta ctcgctattc
    14401 ttttaaagat aaggcaaatt ttcaagttga atttttaaat aatctagtta ctcatttaga
    14461 ggaaggttac aatattgtgc ctattgataa tcatatttat aactgctttt ctacggaaga
    14521 atggtcacag gatttacagg gggattttga gtcctatcag gattttgttt taaaaggtgg
    14581 atttggcttt gtgattctta aaaataatga actgattgct gggatttcct cagggttagt
    14641 ttaccgtaaa gcagttgaag tggaagttgc aactagacca aacgaacaag gaaatggatt
    14701 tgctaaaaag cttggtgctg caatgattct agagagttta aatagagata tgtttccact
    14761 ttgggatgct cataatgagg cttccaaaaa agtagcagaa tttttaggat atgagttatc
    14821 tgaaccttat gaagcttttg aactagagga aattttgata taattatata tgatattgta
    14881 tcttttaaga cgaggtgaat ggctatgaga aatcaacttg cccttagtgg cgaaaaaatt
    14941 cttgaaaaaa tttatcctca actatttcac cacgtcggca tgattcgtgg ggaatactta
    15001 ttgagagagc ttaatcaaaa catcatatta gcaagttgtc agcaatttgt aaaagattat
    15061 cttgatacta tttgctcctt ttacttagat aaggaagttt ggtatcgttt ttctgaatta
    15121 acgaatacag aagccaattg tttagcgggg actagagagt tttttgacga agggcatccc
    15181 ttgtttggct atagaggaac caggcgttta ctggcgtgtt tggatgaatt tcaggctgaa
    15241 gcacatgtcg ttacagaagt ttatcaaacc aatcccaatc tgtctcttat ttttcctttt
    15301 gtcaatgatg ccgaccaatt aaaacaagct attacagtat tgcgtcagta tggctttact
    15361 gggaaagtcg gaacgatgat tgaattaccg tcagcgtatt ttgacttatc tagtatactg
    15421 gaaacgggca tttcaaagat tgtagttgga atgaatgatt tgacttcctt tgtttttgcg
    15481 actatgagaa acagtcaatg gcatgatatg gaaagtccaa taatgttaga tatgctaaga
    15541 gatatgcagg ataaagcaag aaagaacaag attaattttg ctgtagcagg ctatctgaat
    15601 acttctttca tacaaaaaat gaatcagttg ggtatcaagt gcattatcca ctacagttct
    15661 attccagaga tttttgattt agagattgac catccagatc atcttaaaca cataaaagaa
    15721 gaaagtaaaa aattacaaag gagtacccat gataccgcaa gaaatgtgga ataaatacaa
    15781 gcaaatcaat ccttctatcg gagatgaaat cgatgcttgg gcttttggag ttgaaccaga
    15841 ccttttaggg gatttggtgt ttaaaggaga aaagacagca acagcatcag cctatgacct
    15901 ctatgtacta gaagacgaac cacttcccca agtagggacc ttcgatgtca ttttagatag
    15961 tcaaaatcag gctgtctgca ttgtcgaaat tacaaaggtt tctgttgaac tcttcaatca
    16021 agtttctgcg caacatgcct ttaaggaagg tgagggagac aaatcacttg cctattggcg
    16081 ccaggttcat gaggactttt tcacagactg tttgggtgaa gtagggctga cttttacacc
    16141 tgaaagcaag gttgttttag aagaatttcg caaggtctac ccactgtaga ctattagaag
    16201 gaagaaagtt ttggaaatcg ctgtccaatc cttttttctc aagcaaaata tgatataata
    16261 agtttgtttg aagaagagca gcagctctta aacttagaat aggagaaaac tatgcaagca
    16321 gttgaacatt ttattaagca atttgttcct gaacattatg atttattttt agatttgagt
    16381 cgtgagacca agactttttc tgggaaagtg accatcactg gtcaagcaca gagtgaccgc
    16441 atctccctcc accaaaaaga cttggaaatc acctctgtag aagttgcagg tcaagctcgt
    16501 ccatttacag ttgaccatga caatgaagcc cttcatatcg aattggctga ggctggtcaa
    16561 gttgaattgg ttcttgcctt ttctggtaaa attacagaca acatgacagg gatttaccct
    16621 tcttattata cagttgatgg agtcaagaag gaggtcttgt ctactcagtt cgagagccat
    16681 tttgcgcgcg aagctttccc atgtgtggat gagcctgaag ccaaagcaac ttttgacctc
    16741 tctcttcgct ttgaccaagc agaaggtgaa ttggccttgt caaacatgcc agaaatcgat
    16801 gttgaaaacc gtaaggaaac aggtatctgg aagtttgaga caacacctcg catgtcttct
    16861 tacttgttgg cctttgttgc tggtgatttg caaggggtga ccgctaaaac taaaaatggt
    16921 accctggtag gtgtctactc aaccaaagca catccacttt caaatcttga tttctcactg
    16981 gatatcgctg ttcgctctat cgagttttac gaagattact atggagttaa gtacccaatt
    17041 cctcaatctc tccacatcgc ccttcctgac ttctcagctg gtgctatgga aaactggggt
    17101 cttgtgacct accgtgaagt ttacttggtt gtcgatgaga actctacatt tgctagccgt
    17161 caacaagttg cccttgttgt ggcccatgaa ttggctcacc aatggtttgg gaacctcgtg
    17221 actatgaaat ggtgggatga cctttggctc aatgaaagtt tcgctaatat gatggaatac
    17281 gtctgtgtgg ataccatcga accaagctgg aatatctttg aagatttcca aacaggtgga
    17341 gtacctcttg ctcttgaacg tgacgctact gatggcgttc agtctgtcca cgtcgaagtt
    17401 aaacatccag atgaaatcaa tacactcttt gacggcgcta tcgtctatgc caaaggaagc
    17461 cgtctcatgc acatgcttcg ccgttggcta ggagatgctg attttgctaa aggtttgcat
    17521 gcctactttg aaaaacacca atacagcaac accattggta gtgacctttg ggatgccctt
    17581 ggtcaagcgt caggacgtga tgtcgcagcc ttcatggatt cttggttgga acagcctggt
    17641 tacccagttc ttactgtcaa agttgaaaat gatgtcttga agatttcaca aaaacaattc
    17701 ttcatcggtg agaacgaaga caagaaccgt ctctgggtgg tgcccctcaa tagcaactgg
    17761 aaaggcttgc ctgatacact cgaaactgaa agtatcgaaa tccctggcta cgcagctctt
    17821 cttgctgaaa atgaaggagc tcttcgtctc aacactgaaa atactgccca ctatattacc
    17881 gactatcaag gagacttgtt agaagctgtt cttgctgagc tagagacact tgataacaca
    17941 agcaaactgc aaattgttca agaacgtcgt ttgttggctg aggcagggca catttcttat
    18001 gcagacttgc ttccagttct tgataaactt gctaaggaag agtcttatct ggtggtttca
    18061 gctgtttctc aagtgatttc agcccttgag cgctttattg atgaaggaac ggatgctgaa
    18121 acagccttta aaggactggt tgctaaattg gctcgtcata actatgaccg tcttggtttt
    18181 gaagctaaag acggagaatc agatgaggat gaattggttc gtcagctggc tgtttcgatg
    18241 atgattcgct caaatgatgc agaagctagt caagtcgcta gccaaatctt cgcaacacac
    18301 aaggagaatc ttgcaggact cccagcagct attcgctcac aagttctgat taatgagatg
    18361 aaacatcatg agactaaaga cttgttagca ctttatcttg atacttatac tcacgcaaca
    18421 gatgctgtct ttaaacgcca gttggcagca gctcttgcat acagtacaga tgcggataat
    18481 atccaaaacc tgattacttc ttggaaggac aaatttgtgg tcaaaccaca ggacttgtct
    18541 gcttggtatt accaattcct agctcatcaa gcaactcaga aaacagcttg gtcttgggcg
    18601 cgtgaaaact gggcttggat taaggcagcc cttggaggag atatgagctt tgatagcttt
    18661 gttatccttc ctgctcatgt atttaagact cagcaacgct tggcggaata caaggagttc
    18721 tttgagccgc agctttctga ccttgctctt agccgtaaca tcggtatggg aatcaaggaa
    18781 attgcagcac gtgttgactt gattagccgt gaaaaagctg cagtcgaagc agttgttctt
    18841 caatacggaa atgcataaat aagcctaaaa taaaaagaaa
//
LOCUS       DAVMJI010000037        18406 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.037, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000037 DAVMJI010000000
VERSION     DAVMJI010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18406
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.037"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            96..1577
                     /locus_tag="VYR58_001681"
     CDS             96..1577
                     /locus_tag="VYR58_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV3622798.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1938..2939
                     /locus_tag="VYR58_001682"
     CDS             1938..2939
                     /locus_tag="VYR58_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV3622799.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3089..4006
                     /locus_tag="VYR58_001683"
     CDS             3089..4006
                     /locus_tag="VYR58_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV3622800.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKVDFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4017..4907
                     /locus_tag="VYR58_001684"
     CDS             4017..4907
                     /locus_tag="VYR58_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV3622801.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            4936..6552
                     /locus_tag="VYR58_001685"
     CDS             4936..6552
                     /locus_tag="VYR58_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV3622802.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6562..7881
                     /locus_tag="VYR58_001686"
     CDS             6562..7881
                     /locus_tag="VYR58_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV3622803.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVVTGTDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDNQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8092..8164)
                     /locus_tag="VYR58_001687"
     tRNA            complement(8092..8164)
                     /locus_tag="VYR58_001687"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8129..8131),aa:Lys,seq:ctt)
     gene            complement(8429..9700)
                     /locus_tag="VYR58_001688"
     CDS             complement(8429..9700)
                     /locus_tag="VYR58_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV3622804.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            9998..10213
                     /locus_tag="VYR58_001689"
     CDS             9998..10213
                     /locus_tag="VYR58_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622805.1"
                     /translation="MMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEILD
                     LYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10203..10451
                     /locus_tag="VYR58_001690"
     CDS             10203..10451
                     /locus_tag="VYR58_001690"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622806.1"
                     /translation="MKNRIIDVFEVVNRLLVITVENPDFEDLRVNQFVKIGDKKYRVR
                     SVPMIHSTPPQSVLDRDTFTIDYTDDELLDKEAVFTTH"
     gene            10588..10767
                     /locus_tag="VYR58_001691"
     CDS             10588..10767
                     /locus_tag="VYR58_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV3622807.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            10804..11256
                     /locus_tag="VYR58_001692"
     CDS             10804..11256
                     /locus_tag="VYR58_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV3622808.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11547..12017
                     /locus_tag="VYR58_001693"
     CDS             11547..12017
                     /locus_tag="VYR58_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV3622809.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12036..13124
                     /locus_tag="VYR58_001694"
     CDS             12036..13124
                     /locus_tag="VYR58_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV3622810.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLMLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            13105..13533
                     /locus_tag="VYR58_001695"
     CDS             13105..13533
                     /locus_tag="VYR58_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV3622811.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYKLMPIEEFLNSKQAVPQLQGRLRDYLEESL"
     gene            13530..14003
                     /locus_tag="VYR58_001696"
     CDS             13530..14003
                     /locus_tag="VYR58_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622812.1"
                     /translation="MITLVRAGAEDLETIIAIQRASFKAVYEKYHDEYDPYLEDCERI
                     KWKLVERPNSYYYFVKEDEENIGFLRVQTNAELTKAWLGTAAILPQYQGKGYGSKGLS
                     LLEKEFPTITQWDLCTVLQDAGMVAFYEKNGYRQIHIEAEKEGMDMVYMKKLIEK"
     gene            14141..15091
                     /locus_tag="VYR58_001697"
     CDS             14141..15091
                     /locus_tag="VYR58_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV3622813.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPETVDVAAVEADLQARLAELTDFMDLGEVKMGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            15093..15836
                     /locus_tag="VYR58_001698"
     CDS             15093..15836
                     /locus_tag="VYR58_001698"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV3622814.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVSGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15847..17643
                     /gene="pepF"
                     /locus_tag="VYR58_001699"
     CDS             15847..17643
                     /gene="pepF"
                     /locus_tag="VYR58_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV3622815.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(17703..18380)
                     /locus_tag="VYR58_001700"
     CDS             complement(17703..18380)
                     /locus_tag="VYR58_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3622816.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
BASE COUNT         5727 a         3172 c         4016 g         5491 t
ORIGIN      
        1 ttttaggaaa agtcgttata tcatgctata cctattcttt gtggtataat tgcaagaggt
       61 ttaatccgat aatttataaa gagagaaaga tattcatgag agatttatta tctaaaaaaa
      121 gtcataggca attagaatta ttagaattat tatttgaaca taaacgttgg tttcatcgtt
      181 ctgaactagc agagttatta aattgtacag aacgtgcagt caaagatgat ctatcccatg
      241 ttaaatctgc ttttcctgac ttgatttttc attcttctac taatggtata cgcattatta
      301 ataccgatga tagtgatatt gaaatggttt accatcattt ctttaaacat tcaactcatt
      361 tttcgatttt agaattcatc ttctttaatg aaggttgtca agctgagagt atttgtaaag
      421 aattttatat cagttcatct tcgctctatc gtattattag ccaaatcaat aaagtgatta
      481 aaaggcaatt tcaatttgaa gtcagtctga cccctgttca aatcattgga aatgagagag
      541 acattcgtta cttttttgca caatattttt cagaaaaata ttatttccta gaatggccat
      601 ttgaaaattt ttcatcagag ccactatctc aattgttaga attggtttat aaggaaacaa
      661 gctttccaat gaatttgtca acgcatagaa tgctaaagtt gctcctagtt acgaacctat
      721 atagaataaa gtttggtcat tttatggaag tagataaaga ttcttttaac gaccaaagtt
      781 tggatttttt aatgcaggca gaaggaatag aaggtgttgc tcagagtttt gaatcagaat
      841 acaatatctc tttagatgaa gaagttgttt gccaattatt tgtgtcttac tttcaaaaaa
      901 tgtttttcat agatgaaagt ctctttatga aatgcgtaaa aaaggatagt tatgttgaaa
      961 aatcttacca tctattgagt gattttattg atcagatttc agtcaagtat cagattgaaa
     1021 tggagaataa ggataatctg atttggcatc tgcataatac cgcacatctg tatcgtcaag
     1081 agttgtttac tgagtttatt ttatttgatc aaaaagggaa tacaatcagg aactttcaaa
     1141 atatttttcc aaaatttgtt tcagatataa aaaaagagct ttctcactat ttagagactc
     1201 ttgaggtttg ttctagttca atgatggtaa atcatctatc ttataccttc atcactcata
     1261 ccaaacattt ggtgattaat ttgctacaaa atcagcctaa actaaaggtt ttagttatga
     1321 gtaattttga tcagtatcat gcaaaattcg ttgcagagac actttcttat tactgtagca
     1381 ataattttga actggaagtt tggactgaat tagaattatc aaaggaatct ttagaagatt
     1441 caccttatga tatcattatt tctaatttta ttattcctcc tattgaaaat aagagactca
     1501 tctattcaaa taatataaac acggtctcac taatatattt gttaaatgcc atgatgttta
     1561 ttcgattaga tgagtaacca aaaataacaa aaaacgctat ttcgcgtttg aactgtacct
     1621 caaaagttag acagaaaaag tctaattttt ggggtgtttt tgttaagaaa agaccttcaa
     1681 tcatttaagc aaaatgtaca tctagattta tagccatcta aaactcttgc tttttttgta
     1741 gaagatacga aaaaagccat gaaaccaagg cttttcctgt tttatgtaga tgtttacaca
     1801 tgaaaattga agtattttca aaagctaatt ggagtgattt tattcatgat gggataaatg
     1861 atctggccaa aaatgattga gaaatagttg cttaaaaagc atttgcatga tactatatat
     1921 tgaaaggagg tgataatatg gtagaacaaa gaaaatcaat taccatgaaa gatgttgctt
     1981 tagaagcagg agttagtgtt ggaactgttt cacgtgtaat taataaagaa aaaggcatta
     2041 aagaagtaac tttgaaaaaa gtggaacaag cgattaaaac tttgaattac attccagatt
     2101 actacgctag aggaatgaaa aaaaatcgaa cagaaacgat tgcaatcatt gtaccaagta
     2161 tctggcatcc cttcttttca gaatttgcta tgcatgtgga aaatgaagtc tataagagaa
     2221 ataacaaatt actcttatgt tctataaatg gtacaaatag agagcaagac tatctggaga
     2281 tgttgcgtca taataaagtt gatggagtgg ttgccattac ctatagtcca attgaacatt
     2341 acttgacgtc aggaattccc tttgttagta ttgaccgcac atactcagat attgccattc
     2401 cttgtgtttc atcagataat gatgcaggtg gaagagaagc agctaaacaa ttaattagta
     2461 aaggatgtca gcatttagcc tttgtgggcg gacataatac aaccattaat gaaaccaaac
     2521 gtcgtagaat ttcatttgaa aagtatgtcc aagagcataa aatacctctt agtatttttg
     2581 atttggatga gacagttact gactattatg gaaagctaga gagtttcttg gaagaaaatt
     2641 cttctataga tggaattttt acaatcaacg attttacagc tttggatgtg attgaaatac
     2701 tagaaaaaaa tggcaaacgt attcctcatg atgtccaaat tattggatac gatggaatta
     2761 aaatggctgg agatagagat tatctacttt caactattga acaaccattg gaagaaatgg
     2821 caaaagaagc ggttcgtatt ttgtttgata taattgatgg aaagactgtt aatttgcaga
     2881 caatcctacc agtaaaattt gttgaaggaa aaacaacaaa aaatgaaaat aagtcttgac
     2941 agaaagcgtt atcaatgata gaatgaattc agataaaaag atttattttt aaaacaaaaa
     3001 tgaaacgttt caaaaaaaga aataaaaaga cagcgccaag cgctatcttt tctagaaaaa
     3061 atgaaacgtt tcaaaaaagg aggttgctat gaatagcaaa gcgaagcaag tttctctttg
     3121 ggaaagaatc aagaaacaaa aactcttgtt attgatgact gtccccggtt tagttttaac
     3181 ctttatcttt aaatacatcc ctatgtatgg ggttttaatc gcatttaaag attacaatcc
     3241 tttaaaagga attttaggga gtgattggat tggtttttct gagtttacaa aattcatatc
     3301 ctctcccaac tttggtatct tgttagccaa cacattaaaa ttaagtatct atggtttatt
     3361 gcttggcttt ttaccaccaa tcattcttgc gattatgctc aatcaactct tgagtgaaaa
     3421 agtcaaaaaa cgaattcagc tcattttata cgcaccaaac tttatctcag tcgttgttat
     3481 tgtcggtatg attttcctct tcttttcagt gggaggacca atcaacaatt ttctttctat
     3541 gtttggaatg aaggttgact tcttgacaaa tccagacttc tttagacctt tatacatctt
     3601 tagtggtatc tggcaaggaa tgggctgggc ttcaacgctc tacacggcaa cattggtaaa
     3661 tgtagatcca gccttagtag aagcagcccg actggatgga gccaatatct tccaacgaat
     3721 ctggcacatt gatattccag ctcttaagcc tattatggtt atccaatttg ttttagctgc
     3781 aggtggaatt atgaatgtcg gatatgaaaa agcattcttg atgcagacat cgttaaattt
     3841 gccaacttct gaaattatct cgacatatgt ctataaagtt ggtcttgtat caggagacta
     3901 ttcttactca acagcggttg gtttgtttaa tgcagtgatt aacgtagtat tgcttgttgc
     3961 agttaaccaa atcgttaaac gcatgaataa tggtgaagga atttaaggag gaaagtatga
     4021 aaaattcgat tatggataca aaatttgata gacgtatctt actcttaaat aaaatcatta
     4081 ttgtctttat cgttttgatg actttgcttc ctttacttta tatcgtcgta gcatccttta
     4141 tggatcctaa ggttctggtt agtagaggga ttagctttaa tccagccgat tggactgtag
     4201 aaggttacca gcgtgtattc agtgaccaat ctattctaag aggttttatc aattctctac
     4261 tatactcttt tggatttgca gctttaacag tattgctatc tgtgtttaca gcttatcctc
     4321 tttctaagaa agacttggtt ggacgtcgtt ggattaacta cttcttgatt gtgactatgt
     4381 tctttggtgg tggtttagtc ccaacttact tgctcgtaaa agaattggga atgctcaata
     4441 ctccatgggc tatcattgtt ccaggtgctg tcaacgtttg gaatattatt cttgctaggg
     4501 cctatttcca aggattgcct gaagaattag ttgaagctgc tgtcattgat ggtgcaaatg
     4561 atttacagat tttcttcaaa atcatgcttc ctcttgcaaa accaattatg tttgttctct
     4621 tcctttatgc ttttgtagga cagtggaact catactttga tgcaatgatt tatatcaagg
     4681 atccaaactt ggaaccattg caacttgtac ttcgtaaaat tctcattcag agccaaccag
     4741 gtcaagacat gattggagca caagcggcta tgaatgaaat gaaacgttta gctgaattga
     4801 ttaaatacgc aactattgtc atttccagct tgccattgat tgttatgtat ccattcttcc
     4861 aaaaatactt tgataaagga attatggctg gttcacttaa aggataaaaa aagaaaaaat
     4921 aaaaggagtt ttctcatgaa attcaaaaca ttctcaaaat cagcagtttt gttgacagct
     4981 agtttagcag tacttgcagc ctgtggctca aaaaatacag cttcaagtcc agattataag
     5041 ttggaaggtg taacattccc gcttcaagaa aagaaaacat tgaagtttat gacagccagt
     5101 tcaccgttat ctcctaaaga cccaaatgaa aagttaattt tgcaacgttt ggagaaggaa
     5161 actggcgttc atattgactg gaccaactac caatccgact ttgcagaaaa acgtaacttg
     5221 gatatttcta gtggtgattt accagatgct atccacaacg acggagcttc agatgtggac
     5281 ttgatgaact gggctaaaaa aggtgttatt attccagttg aagatttgat tgataaatac
     5341 atgccaaatc ttaagaaaat tttggatgag aaaccagagt acaaggcctt gatgacagca
     5401 cctgatgggc acatttactc attcccatgg attgaagagc ttggagatgg taaagagtct
     5461 attcacagcg tcaacgatat ggcttggatt aacaaagatt ggcttaagaa acttggtctt
     5521 gaaatgccaa aaactactga tgatttgatt aaagtcctag aagctttcaa aaacggggat
     5581 ccaaatggaa atggagaggc tgatgaaatt ccattttcat ttattagtgg taacggaaac
     5641 gaagatttta aattcctatt tgctgcattt ggtatagggg ataacgatga tcatttagta
     5701 gtaggaaatg atggcaaagt tgacttcaca gcagataacg ataactataa agaaggtgtc
     5761 aaatttatcc gtcaattgca agaaaaaggc ttgattgata aagaagcttt cgaacatgat
     5821 tggaatagtt acattgctaa aggtcatgat cagaaatttg gtgtttactt tacatgggat
     5881 aagaataatg ttactggaag taacgaaagt tatgatgttt taccagtact tgctggacca
     5941 agtggtcaaa aacacgtagc tcgtacaaac ggtatgggat ttgcacgtga caagatggtt
     6001 attaccagtg taaacaaaaa cctagaattg acagctaaat ggattgatgc acaatacgct
     6061 ccactccaat ctgtgcaaaa taactgggga acttacggag atgacaaaca acaaaacatc
     6121 tttgaattgg atcaagcgtc aaatagtcta aaacacttac cactaaacgg aactgcacca
     6181 gcagaacttc gtcaaaagac tgaagtagga ggaccactag ctatcctaga ttcatactat
     6241 ggtaaagtaa caaccatgcc tgatgatgcc aaatggcgtt tggatcttat caaagaatat
     6301 tatgttcctt acatgagcaa tgacaataac tatccaagag tctttatgac acaggaagat
     6361 ttggacaaga ttgcccatat cgaggcagat atgaatgact atatctaccg taaacgtgct
     6421 gaatggattg taaatggcaa tattgatact gagtgggatg attacaagaa agaacttgaa
     6481 aaatacggac tttctgatta cctcgctatt aaacaaaaat actacgacca ataccaagca
     6541 aacaaaaact agaggttgat tatgggagat aagaaataca cagtagaaaa agccaatcgt
     6601 tttatagcag aaaataaaca tctcgttaat actcaatata agcctgaaga acatttttca
     6661 gctgagattg gttggatcaa tgatccaaat ggatttgtct attttcgtgg agaataccat
     6721 ctcttttatc aattctatcc atatgatagt gtttgggggc ctatgcactg gggacatgct
     6781 aaaagtaagg acttggtgac ttgggagcac ttgccagtgg cacttgctcc tgaccaagat
     6841 tatgaccgaa atggttgttt ctcaggctct gccattgtca aggatgatcg cctctggctc
     6901 atgtacactg ggcatatcga agaaaaaacc ggtgtccgcc aagtgcaaaa tatggcattt
     6961 tcagatgacg ggattcactt tgaaaagatt tcccaaaatc cagttgtaac tggaacagac
     7021 ttgccagatg agttgattgc tgctgatttc cgtgacccaa aactctttga aaaagatgga
     7081 cgctattact ccgtagtagc tgccaaacac aaggataatg tgggctgtat cgttctacta
     7141 gggtccgata acctagtaga atggcagttc gaatccatct ttttaaaagg gggagaacac
     7201 caaggcttta tgtgggaatg cccagattac ttcgagttag atgggaaaga ttgccttatt
     7261 atgtcaccca tgcgttatca gcgtgaggga gactcatatc ataacatcaa ctcatcgctt
     7321 ttgttcacgg gtaaggtaga ttggggagaa aaacgtttta tcccagaatc agttcaagaa
     7381 attgatcatg gccaagactt ctatgcgcct caaacattgt tggacaatca aaatcgtcgt
     7441 atcctgattg cttggatgca gacatggggg cgtacccttc caacccatga ccaagaacac
     7501 aaatgggcat gtgccatgac tttacctaga attctaagat tggaagatgg caaactaaga
     7561 caattccctg ttaaaaaagg ccaatatcaa atccaaatag ataaagattg tcattaccac
     7621 ttaggaaatg atatagatta tcttgaattt ggttatgaca gtaatgcgca gcaagtttac
     7681 attgatcgta gccatcttat tcaaaaaatt ctaggtgaag aagaacagga cactagtcga
     7741 cggtatgtag atattgaagc taaagaattg gaagttgttc tagataaaaa ttccatcgag
     7801 atttttgtca atcaaggtga agcaagcttg actgcaactt attacttaac ggtgccagct
     7861 gagctatcac gaattgatta aaaattaagt tatttctcct aaagaaaaag ttctctttct
     7921 aaaatagtgg aaagaggact ttttgtgttt tgggtatata agcttagttt atggtatttg
     7981 taaaattggt gttggattat gatttaaact agttttctaa agaatttgaa aaaaatttta
     8041 tttaagcaaa aaaaagccct atattataag acttttcctg ttgtatttaa atgcccccta
     8101 cagggatcga acctgtgacc cacggattaa gagtccgctg ctctgccagc tgagctaagg
     8161 aggcaaagaa aaaagctgta ttggtgccga aacttcacgg tttgtattga acccgcgcaa
     8221 ttaagcaggt gggcaactcg ctctaactga agctgtttcc gtgtgagacg gcctacatgc
     8281 tgttagaaga cttttgtttc cctaataata caaaaaatag tcggtcaaca cttaagtgtg
     8341 aagtcgtaca ccacagcgtt tctatattta tatgatacca ctttttcaaa aaaaatcaag
     8401 aggaaagtgc aattttttga aaaggatttc agatttttcg caaatggtcg atagcttcct
     8461 ttctttgagc caaagcccgt tcatatttac cagtatcttc tgcttggaaa tagtgatgat
     8521 tacgaatttt ttctggcaga tagtcttgct ttacccaatt tccaggatag ttgtgtggat
     8581 agagatagtc ttgggcattc cccagttcct tgcttccact gtagtgccca tcacgtaggt
     8641 gtcgcggaat aggcaagtgc cctgatgttt tgaggtcagc aagtgcctta tccatagcta
     8701 cataggctga gttggatttt ggagaaaggg ccaaatcaat cacgacattg gcaatgagaa
     8761 tgcgggcttc tgggaaccca atcttctggg cagcatccag agcagtcacg gtatgaatct
     8821 gggcctcagg attggctaag ccgatatctt cataggcgat aacagtcaag cgacgagcga
     8881 gactaggcag atccccagcc tcaatcaagc gggcagtata gtggagactg gcatccacat
     8941 ctgagccacg gatagacttt tgcagggcag atagaacatc atagtgaccg tctccatcct
     9001 tgtccatagt gatgtagctt ctctgaagac tattttccat gatgtctaag gtgatgtggc
     9061 gaatgccctc gtcattctca ggggtagaga gaacagccaa gtccagtgag ttaaaggcag
     9121 agcgaaggtc tccgtttgta gaggttgcga tgaaatccag cgcatcctca tctagttcta
     9181 ttggaaaatc aaaaccacgt tcagggttac ttagagctat ctgcagggcc tctttgacgt
     9241 cttggttaga cagaggttcc aactcaaaaa tttgaacacg gctacgaatg gcaggagtga
     9301 cggaaaagaa aggattttca gttgttgctc caatcatgat gaccagtcca ctttccaaga
     9361 gaggcaagag gaagtcttgc ttggtcttat ctagtcgatg aatttcgtct agcaatagga
     9421 cgagaccacc agaaaattta gcttcttccg agatttcttg cagtcgcttt ttactatcaa
     9481 ctgtcgcatt gaaagttcga aaggcatact tggtcgttcc agcgatggca gaggcaatac
     9541 tggttttgcc gattcccgga gggccatata gaatcatgga ggacaggcgg ttggcttcca
     9601 ccatgcggcg gatgattttt ccaggtccga ccagatgctc ctgaccgatg acctggtcga
     9661 tggttttagg gcgcatgcga agcgcgagat tgtctggcat agcagtcctt tctagcgtgg
     9721 atttgagtag aatgactcat ctactatatc ttactatgtc cattctagcc tattagttgt
     9781 gatatttcaa tggttttgta ataatcaggg agtgagatag aatctttttt actatttaat
     9841 ttaatgagga gaggtatcag catgagagat ttgattttcc ttaaagctca aaataggata
     9901 gttgagccta aagaagtgga agtgctgact tgagaaataa tattgctgaa tgtcattgta
     9961 tgaactataa tgaaaagaga ggtgataagc aatggaaatg atggaactac caagtcagga
    10021 aattttgatt tttacaaaac aaattcgtca ttggattctt agtgatcaag ttatttcagg
    10081 gaaaagaaaa cttttcttcc gggaagatac tccaaaagag attttagatt tgtacgaaaa
    10141 cattaaatct aaacttgatt ttgcttacca agaagttcat tctaataatg ggttgaaaaa
    10201 atatgaaaaa tagaataatt gatgtttttg aagtagtaaa tcgcctcctt gtaataactg
    10261 ttgaaaatcc tgatttcgaa gacttgagag ttaatcagtt tgtaaaaatt ggagataaaa
    10321 agtatagagt acgcagtgtt cctatgattc attcaactcc gcctcaatct gtcttagatc
    10381 gagatacttt tacaattgac tatacagatg atgaattgct cgataaagaa gcagttttta
    10441 ctactcatta gaaaaatagg tatgaataaa ttggcttccc ttagaaccac atctaggggc
    10501 ttttatgtat aatagaataa taagtatcac tcctttacaa tacgtgtaac acgtgttata
    10561 atggtgttgt caggaggtaa aagcgctatg cctatgacac aaaaagagat ggttaaactc
    10621 cttacggccc atggttggat aaagactaga ggcggtaaag gctcccatat taaaatggaa
    10681 aagcaagggg aaagacctat cacaatcctt catggtgagc tgaataagta cactgaaaga
    10741 gggataagaa agcaagctgg gttgtaaaat tcagcccctg ctttttgata tggaggtagt
    10801 gaaatgttag ttacgtatcc agctttattt tattatgacg acacagacgg aacagaagcg
    10861 acttattttg tccatttccc agattttgaa tactcagcta cacaaggaga ggggatttct
    10921 gaggctttgg ctatggggtc ggagtggcta gggataactg ttgcagattt gatagagagt
    10981 gatggagagt tacctcagcc atcagatatc aatagcttgt ctttaattga taatgatcct
    11041 tttaaagatg atgaagattt cgtgtcaacc tatgaccttg ataaatcttt tatttctatg
    11101 gtatctgttg atgtatcaga atacctagga agtcaggaac ccattaaaaa gactttgacc
    11161 ataccaaaat gggcagataa gttgggacga gaaatgggac ttaacttttc tcagactttg
    11221 acagacgcta ttgcagataa gaaagttcaa gcctaagatt aagcgtggta tcgtggtaat
    11281 agtcaataaa aaagcacgtc cacttgtgct agttactcgc ctattgattt tatagattta
    11341 ttagcccttt cgagggcttt ttatattgat ttttatgaga aatgaagaaa tcagactttt
    11401 aagaaaatca ctgataccaa gggtttaaat gaggtaatat ggtataatta ggacataaaa
    11461 taattttgtg gtaagatggt agtatctatt ttagcatatt tccgagcaat cggggcgatt
    11521 aaagagtcgc atagaaagag gacaaaatgg caacatacgg atttttagat attttagagg
    11581 aagagttgga caagaacttt ccctttgact ttgagattag ttgggacaag cgtaaccacg
    11641 cggtagaagt gagttttcta ttggaagcgc aaaatgctgc aggtgtggag atggtggatg
    11701 aagatggaga ggtttcatca gatgacattc tttttgagga agcggtcctt ttctacaatc
    11761 ctgccaagtc aaccgtcaat gcagaagact atttaacggt tatcccttat ctacctaaaa
    11821 aaggattttc tcgcgagttt ttagcttatt ttgccctttt cctcaaagat actgcggagg
    11881 ttgggctaga taccctcatg gactttttgg aagatccaga agcagaggaa tttgttatgg
    11941 aatggaatca agaagtcttt gaagaaggaa aagttggctt ggaagaggga gaattttatc
    12001 cttatccaag atactaggag ttggttggag gtgttatgaa gaaaattggg acttatttgg
    12061 tttatgtgct agctgttgtc tttattatgc tagcttttgc ttgtggaaca atcgcatttg
    12121 cagagttggg gtattccgca gttttagcct ttacttttgg ttatgccttc gctcttctaa
    12181 gcatgtattt aatctttatt cttcatgagc tgggtcatgc tttttgtggc tacttgacag
    12241 gctatcggct ggtggctttt ggattaggac attttatttt gaccaaaaag tcaggcaggt
    12301 ttcatcttag tagaacagcc attctgaaaa atgttggtgc tcaatacatt ggtttaaaag
    12361 aggatgaaag cgatcaaaga atcatcctga tgctttcagg aggcttgatg gttcatctcg
    12421 gcttgatatt attggcgata gtgtttggat ttttgacaag aagctggtat tttgcaggga
    12481 cttggatttt tcttaattta tctttcttcc taaataacat tttgccagtc gacatcaccg
    12541 atggagcaaa aatttgggaa ttactacaac accctgaaaa taccaaatac gcctacctga
    12601 tgttgaggca ttctgcccag accttgctag ctcctcaaga atatgattta aaagactttg
    12661 ttcaagcagt tcctgaggat gcacgaggga gttttgcgga tggtgtatta ggtatgcaag
    12721 gtgaagtttc cattttggaa gggaaggaag aagtagctaa acagcagttt caagcattac
    12781 ttgagaggac aactactccg atgatgcaga cagttgccca actatccctg cttcatatcg
    12841 ccttgttgga aggagatttt gagcaagcgg agcaatatgc tagtattcga caggtcaaat
    12901 cgtttctgtc tctcaaactg tccaatcttc aagtgataca agcttggtat caatttaagg
    12961 taaagaaaga tgtagatcga actcgtaagg ctctcaagat tgctagacag aaaatggata
    13021 gtagtcgaat gttgagggac gagaaacgct attatgaaaa cttgttagca gagctggaaa
    13081 aggaaatgtt agaaggaact gaagatggaa ctagaaattt ctgatttcca aggttgcaag
    13141 attgccctct tttgtgggga taagctactg acgattttgc gtgatgacaa ggacgatatc
    13201 ccttgtccca acatgtggga gttgccaggt ggtggccgtg aaggggacga aagccctttt
    13261 gaatgcgctc ggcgtgaagt ttatgaggaa ctgggaattc atttagatga agactgtctg
    13321 ctttggagca agatttatcc tagcgtaatt tttaaaggca agaaatcggt ctttatggtt
    13381 ggtcagctaa gacaagaaca atttgacaat atcatcttcg gagatgaagg acagggctat
    13441 aaattgatgc ctattgagga atttctcaat tctaaacagg cagtgcctca gttgcaggga
    13501 agattgagag attatttgga ggaaagttta tgataacact tgttcgagcg ggagcagagg
    13561 atttagaaac tattattgca attcagagag ccagctttaa ggctgtttat gaaaaatacc
    13621 atgatgaata tgacccttat ctcgaggact gcgaacgaat taagtggaaa ttagtcgagc
    13681 gtcccaatag ctattactac tttgtaaaag aagatgaaga aaacatcgga tttttacgag
    13741 ttcagaccaa tgccgagtta acgaaagctt ggttgggaac ggcagcgatt ttgcctcagt
    13801 atcaaggaaa agggtatgga tctaaaggtt taagcttact ggaaaaagaa tttccaacca
    13861 tcacacaatg ggatttgtgt acggtgttac aggatgcagg catggttgct ttttacgaga
    13921 aaaacggcta tcgtcaaatc cacattgagg ctgaaaaaga aggcatggat atggtctaca
    13981 tgaaaaaatt gatagagaaa tagaaaggat ggttcggtta aatttctaaa ctgaacccgc
    14041 cctaaacacg gtgccaaaaa gataaacttc tcttagacac aaacgtcttc agagagtttc
    14101 ctattttggc tttgtgtttt acgggcttgg tatcttaata atggaaacat ggcaagagtt
    14161 aaaagttaca gtgaagcgtg agggagagga gttggtttcc aatctcttga ttgagttagg
    14221 tgcccaaggg gtagcaattg aagacagcat ggactatgtg ggaaatgtgg accgattcgg
    14281 tgaaattttc ccagaggtgg agcaacagga agaaatcgta gtgaccgcct actaccctga
    14341 aacggttgat gtagcagcag ttgaagcgga tttgcaggct cgtctggcag aattgaccga
    14401 ctttatggac ctaggagaag tcaagatggg cacgactgcc ttggctgagg aagactgggc
    14461 tgacaactgg aagaagtatt atgaaccggc acgcatcacc catgacctga ccatcgtacc
    14521 gtcatggacg gactatgagg caacagcagg agaaaagatt atcaagctgg atcctggtat
    14581 ggcctttggg acagggaccc acccaacaac caagatgagc ctctttgcct tggaacaggt
    14641 tcttcgtggt ggcgaaacag tgctagatgt agggactggt tcaggggttc tttctattgc
    14701 aagctcactc ctaggtgcca aggagatttt cgcctatgac ttggatgatg tggcggttcg
    14761 tgtcgctcag gaaaatattg agctcaacac tggtatggaa aatatccatg tagcagcagg
    14821 agacttgctt aagggagttg agattgaagc agatgtcatc gtggctaata tcttggcgga
    14881 tatcctcatt catctaatag acgatgccta tcgtttggtc aaggacgaag gctacctgat
    14941 catgagtggc attatcaagg ataagtggga catggtgcgc gagtcggctg aatcagctgg
    15001 atttttcctc gaaactcaca tggttcaagg ggaatggaat acctgtgtct ttaagaaaac
    15061 caaggatatc tctggtgtga ttggaggcta gcatgcagca gtattttgta aaaggcagtg
    15121 ctatctctcc tgtcactatc gaggacaagg aaaccagtaa gcatatgttt caggttatgc
    15181 gcttgaaaga agaggatgag gttaccttag tctttgatga tggcatcaag cgcttggcgc
    15241 gcgtgctgga tatggaaaat cgtcagtttg agttggtcca agaattaaat gacaatgtgg
    15301 aactaccagt ccaagtgacc atcgcatctg gatttcccaa gggagacaag ctggagttca
    15361 tcgctcaaaa agtaaccgaa ctgggggcta gccaaatctg ggcctttcct gcagactggt
    15421 cagttgccaa gtgggatggc aagaaattgg gtaaaaaagt tgaaaaacta gaaaaaattg
    15481 cccttggagc agccgagcaa agcaagcgta atattgtacc aagtattaaa cttttcgaga
    15541 aaaaagcaga ttttctagct cagctggacc agtttgactc tatcatagta gcctatgaag
    15601 aatcagctaa agaaggagaa gccgctgcgc tcttacaagc ggtctctggt cttgaaacag
    15661 gagccaaact gctctttatc tttggaccag aaggcggtct ctcacctgca gaaatcgaaa
    15721 gttttgaagc taagggagcc gttttggtag gcctaggtcc tcgtattttg cgagcagaaa
    15781 cagcaccgct ttacgcctta tcagccctta gtgttttagt agaattagag aaataagagg
    15841 aagaaaatgg aacaaaaaca ccgttcagaa tttccagaga aggaactctg ggacttaaca
    15901 gccctatacc aagaccgtga ggatttcttg cgtgcaatcg agaaagctcg cgaagacatc
    15961 aaccagttta gccgtgatta caagggcaat cttcacactt ttgaggattt cgagaaggcc
    16021 tttgcggaat tggaacagat ctacattcag atgagccata ttggcaacta tggttttatg
    16081 cctcagacga cggactatag caatgacgaa tttgccaata ttgcccaagc tgggatggaa
    16141 tttgaaacag atgccagcgt agccttgacc ttctttgacg atgccttggt ggtagcagac
    16201 gaggaagtct tggaccgttt gggtgaattg cctcacttga cggcagctat tcgtcaggcc
    16261 aaaatcaaaa aagcccacta tctaggggct gatgtggaga aggccttgac caatctcggt
    16321 gaagttttct atagtccgca ggacatttat actaagatgc gagctgggga ttttgaaatg
    16381 gctgactttg aagcccatgg caagacctac aaaaacagct ttgtcaccta tgagaatttc
    16441 taccaaaatc acgaggatgc cgaggttcgt gagaaatcct tccgttcctt ctcagaggga
    16501 cttcgtaagc accaaaatac ggctgcagca gcctatctgg ctcaggtcaa gtctgaaaaa
    16561 ctcttggctg atatgaaggg atacgactct gtctttgatt atcttctagc tgaacaagaa
    16621 gtggaccgtg tcatgtttga tcgccagatt gacctcatca tgaaggactt tgcaccagtc
    16681 gctcagagat acctcaagca tgttgccaag gtaaatggtc ttgaaaagat gacctttgca
    16741 gactggaaat tggacttgga cagcgccctg aatcctgaag tgactattga cgatgcctat
    16801 gatttggtca tgaagtcggt agaacctttg gggcaagaat attgtcagga agttgctcgt
    16861 taccaagaag agcgctgggt ggactttgct gctaacagtg gcaaggattc cggtggttat
    16921 gcggcggacc catatcgcgt acacccttat gtactcatga gctggacagg ccgtttgagc
    16981 gatgtctata ccttgattca tgaaatcggg cattctggtc aattcatctt ttcagacaat
    17041 catcaaagtt acttcaatgc ccatatgtcg acctactatg ttgaagcacc gtcaaccttc
    17101 aatgaattgc tactcagtga ttacttggag aaccagtcta atgacccacg tcaaaaacgc
    17161 ttcgctctgg ctcatcgctt gacagacacc tacttccata actttatcac ccacctcttg
    17221 gaagcagcct tccagcgtaa ggtgtataca ttgattgaag aaggggagac ctttggagca
    17281 agcaaactca acagcattat gaaggaagtt ttgacagatt tctggggaga tgctattgaa
    17341 attgatgatg atgcagcttt gacttggatg cgccaagctc actactatat gggcttgtat
    17401 agttacacct actcagcagg actagtcatc tcgacagctg gttaccttca tcttaaaaac
    17461 tcagaaactg gagctgaaga ctggcttaat ctcctcaaat caggtggtag caagacacca
    17521 cttgagtcag ccatgattat cggtgctgat atttcaacag acaaaccact ccgtgatacc
    17581 atccaattct tgtctgacac agttgaccag attatcgcct acagtgctga gttgggggag
    17641 taaggggata gagaggttgt tatagaatgg gtatggacag ttatttgctt aaaagtccat
    17701 gtttaaatcc cccattcctt ttcgaggaat tctttgccct tctctgtaat ggtaagtgaa
    17761 cgtggcgttt gtgcagggat gaccaattgt ttttcactga aaaattctaa aagagcattg
    17821 ccgagagctc cgccgacatg atttttacgt tcgctccaat ccaaacattt agggcaaaat
    17881 ttccgttttt tctttttcaa ttcatccgta tcaatgtgta attttctttg gaaataagac
    17941 ttcccagctt cagtgagttg gaagtctttt tctgattcgc tgaggagatt ttcttgcaag
    18001 agataattgg taatggaaat gccaagctca ccagcaatat ggtcatagca ggtgcgagcg
    18061 acctttaatt cctttttgtg aatgtgttgt ttataacttt tgacatcacg ctgaggagag
    18121 tagaagctga gaaattccag catttctgca atggcagcac tttttaaaga ataataatga
    18181 aaacgtccat aggtttgtag agtggttacc tgcgcttcgg taagtaattt gaggtgatag
    18241 ctgacagtat gttgcttgat tttggtaaag ctggcaattt cgttaaccgt gtgagctttt
    18301 ccatccatta gaatatctaa aatgtgcatc cgagaagggt ctgataagag ttttgtgatg
    18361 atgaaaatat ctggttccat aaaaattttc tccaaatttc atatat
//
LOCUS       DAVMJI010000038        18215 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.038, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000038 DAVMJI010000000
VERSION     DAVMJI010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.038"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(13..864)
                     /locus_tag="VYR58_001701"
     CDS             complement(13..864)
                     /locus_tag="VYR58_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV3622817.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            1191..1583
                     /locus_tag="VYR58_001702"
     CDS             1191..1583
                     /locus_tag="VYR58_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622818.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            1605..2396
                     /locus_tag="VYR58_001703"
     CDS             1605..2396
                     /locus_tag="VYR58_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622819.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            2389..3030
                     /locus_tag="VYR58_001704"
     CDS             2389..3030
                     /locus_tag="VYR58_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622820.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMILYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            3034..3666
                     /locus_tag="VYR58_001705"
     CDS             3034..3666
                     /locus_tag="VYR58_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3622821.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDIEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            3694..3981
                     /locus_tag="VYR58_001706"
     CDS             3694..3981
                     /locus_tag="VYR58_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622822.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            4127..6640
                     /gene="secA"
                     /locus_tag="VYR58_001707"
     CDS             4127..6640
                     /gene="secA"
                     /locus_tag="VYR58_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV3622823.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            6721..7752
                     /locus_tag="VYR58_001708"
     CDS             6721..7752
                     /locus_tag="VYR58_001708"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV3622824.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            7754..8785
                     /locus_tag="VYR58_001709"
     CDS             7754..8785
                     /locus_tag="VYR58_001709"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV3622825.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            8824..9192
                     /locus_tag="VYR58_001710"
     CDS             8824..9192
                     /locus_tag="VYR58_001710"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV3622826.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            9182..10285
                     /locus_tag="VYR58_001711"
     CDS             9182..10285
                     /locus_tag="VYR58_001711"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV3622827.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFIEASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            10304..12319
                     /gene="recG"
                     /locus_tag="VYR58_001712"
     CDS             10304..12319
                     /gene="recG"
                     /locus_tag="VYR58_001712"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV3622828.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRIQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTAHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            12635..13615
                     /locus_tag="VYR58_001713"
     CDS             12635..13615
                     /locus_tag="VYR58_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV3622829.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            14465..14692
                     /locus_tag="VYR58_001714"
     CDS             14465..14692
                     /locus_tag="VYR58_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622830.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            14980..17892
                     /gene="nanA"
                     /locus_tag="VYR58_001715"
     CDS             14980..17892
                     /gene="nanA"
                     /locus_tag="VYR58_001715"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV3622831.1"
                     /translation="MNRSIQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSS
                     DTKENEYFTMSVLDNTALIEGRGANGEQFYDKYTDAPLKVRPGQWNSVTFTVEQPTAE
                     LPHGRVRLYVNGVLSRTSLKSGNFIKDMPDVNQAQLGATKRGNKTVWGSNLQVRNLTV
                     YDRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKERTIREEF"
BASE COUNT         5544 a         3260 c         4036 g         5375 t
ORIGIN      
        1 agttattaca aattataggt ttgaaaaatc attaatttct ttttcgagta ttttaactaa
       61 tgcctcttct ttggttagtc gtaataaagt tattccttta tcaatcaaat cggagttatg
      121 ttgtagtatt cccaagcgta cttgagagaa tccaagaata tcgtatattt ttaattcttc
      181 tgctaatacc aaaagttgta gggtgattgt ttcacattct ttgaataaat gatgttgaaa
      241 atatacagtg gagagattgg ctaaaaaaga tgataaaaat gcttttgttt ctcggaagta
      301 tttatatttc tcgatggttt tcataattct atcaataaga aggggaagat tttcagaagg
      361 aaagaaaaag agaatggttc caagcaattt caaatcacta atgtaccatg tatccatagg
      421 ttcaagatag tcccaaattt cttcatacaa atctttcaag acgtggttgt ttttgaatcc
      481 tttagttcgt aactctgtga caatttttgt atgacgatag atattttgaa taggaacatc
      541 gtgatgtgtc ttaagatatt tttgacattt ctcagtgagt tcaaccattt ttctagtatc
      601 ttgaaaagta gacggatttt ggctctctac aataatatct cgccttttac taggatggta
      661 ttcgttgcat atatacttga attctgccaa gctcatatca atttgttcaa gaagaaatac
      721 catgttttca aaactgggaa taactttacc gtgttcaata tttgttagag ttgttcgatg
      781 tatgacttgt ccacatacat cttgttgggt caatcctttt gactttcgaa tttctttaaa
      841 aatttgtcca taatcccatc tcatattgtt cctcctaggt aaatgtgaat attttctaca
      901 tttataaaaa acgtagaaaa aggtggtatt attatatcaa aaaggaggga aaaagtcatg
      961 ggctttaaaa aatatttgaa gaatttaccg aaaaactctg gatttttgat ttggagttgg
     1021 attcaactta tctggtttga aacatggttt tggggataaa gaaattagag tctatacata
     1081 ataagtaaag gaggaatttg tatgatatac catcgtttag aataagtcta tatttaaaat
     1141 agaagttata aggaatcttc ttgaataaaa aatgaaagga aacagaaaaa atgaaaatta
     1201 agaaattatt gaaaatggtt attcctgttt taatgataag tgctgttgga actactttcg
     1261 tagaagcaaa tcagataggt gcttttagta attttgttat tactaccagt tataagagaa
     1321 caggttattt gactaaagaa aatgaaggtg cggaatatat catgaactta aatccttgta
     1381 gaaatttaca tcccatgact gttaagcatc gtatagtaaa ttctaatgga gaagctcgta
     1441 gtggagaatc gttaacaacc tgtggtactc gttcaactca tggtaattgg gcaacggttg
     1501 gctatgttta tgcagcagat atggcaagac aaaattggtg ggatttatca gctgccattt
     1561 caggtagttg gtcaccaaat taattcgtaa agtaggtata atttatgaag attcctctct
     1621 taacttttgc aaggcataaa tttgtttatg tcttgcttac tttgcttttt cttgctttgg
     1681 tttatcgtga tgttttgatg acttatttct tttttgatat tcatgcgccc gatctagcta
     1741 aattcgatgg acaagcaatt aaaaatgact tattaaaatc agcattagat tttcgtattc
     1801 tccagttcaa tctaggtttt tatcaatcat ttattattcc aatcatcatt gttttgctag
     1861 gttttcaata tattgagctg aaaaataaag ttttacgatt gagtattgga agagaagtga
     1921 gttatcaagg gttaaaaaga aagttgactt tgcaagttgc aagtatccct tgtttgatat
     1981 atttagtgac tgtgctgata attgcaatta taacctattt ctttgggact ttttctcctc
     2041 ttggatggaa ttctctattt tctgatggaa gtggtttaca aagactccta gatggagaga
     2101 taaaaagcta tttgttcttt acttgtgtcc tactaatcgg tattttcatc aatgcaatct
     2161 attttttaca aatagttgat tatgtgggga atgtgactcg ttcggcaatc acctatttga
     2221 tgtttctttg gcttggttct atgctgctct atagtgcctt gccttactat atggttccta
     2281 tgacgagttt gatgcaagct agctatgggg atgtaagttt gatgaaactc tttactcctt
     2341 atatccttta tattgtccct tatatggtgc ttgaaaaata tgaagataat gtttaagaat
     2401 tttaacaata tttggctaaa gagaaagatc gttttactac ttcgtatagt tctgatgatg
     2461 attttgataa actatctatt gtcaacagcg gttcaaaagc aggatgctgt tatctttttc
     2521 aagagagaat tgatttcaat cttttcctat aatgactatt ctgaagcgaa tttagaaatc
     2581 cccaaactct tgttaaacct ttcgcttttc atggtaggat ggctctctgt cattttactt
     2641 gaaagtgatt tggcagacca ttaccatcac ttgattcgct atcaatcaag ctcctttttc
     2701 gattatacaa ggaaacgatt ggttgtcatt tctaaatttt ttactcaaga tttacttgtc
     2761 tggttccttg gtttacttcc gctaggaatt catttcaaaa cagtcgcact tttcttttta
     2821 cttgctcagt taatgatttt gtacttacta ctgtcttatc tgatagcact gattagtgcg
     2881 ggcgctggtt tttccttttt tctctatttt ttagcatttg tgggacaaga atggatgatg
     2941 gatcatattg taacagtgta tttactactc ttaagcttat tagttatgtt gattgttagt
     3001 cgcttggaag agaaatttaa gaaaggataa acgatgagac ttgaaattat aaatggacag
     3061 aaaatttatg ggaaaagacc tattttaaat cagttgaatt tggtgtttca atcaggaaaa
     3121 atttatggac ttaaaggtga taatggatct ggcaagacgg ttcttttaaa gatacttgct
     3181 ggttatatta agcttgacaa aggaaaagtt cttcaagacg ggaaagtcta cgggataaaa
     3241 aatcattata ttcaggatgc aggaatttta attgaaaaag tcgagttttt atctcattta
     3301 tccctgagag aaaatttgga actgttaagg tatttttcat ctaaagttac ggaaaaaaga
     3361 attgcctatt ggattcaata ctatgattta caggaatttg aagacattga ataccgtcat
     3421 ttatccttag gaacaaagca aaaaatggcc ttgattcaag cctttatttc ctctccttct
     3481 atactctttc tcgatgaacc tatgaatgct ttggatgaga agagtgtgag gttaaccaaa
     3541 caggtcattt tatcttacct gaaaaaagaa aatggtctgg ttatcctgac atcgcacata
     3601 tcggaagata tttcagacct ttgtacagat gtattagttg tcgaaaatgg acatatacaa
     3661 atgtaaagga tatacaatcc taggagatgg cttatggcac atctaaaatc atttattaca
     3721 cgctattcca aggtttatat tggtttagtt ctgctgatct ggctgtcttt cttctttatc
     3781 ccttgggata gagcgattct gggggtaagg attgacatct tcatcataca gaaaatcttg
     3841 ctagcttttg gaattctgtc cattctcatg gccttgctgt ccaagaaagt cagtctcttt
     3901 gtttttggac tgatttgctg tctttctctt tggattaact tatttatcac atttgccatt
     3961 ttgccgattt ttggcaatta aacagtcata aaagtcggag aggttagctt gaaaactaac
     4021 ctctttttcc ttttcaaaat ggggattctt ccttgaaaat aatcagtaat tgtgctaaaa
     4081 ttaaaggaac attctaaaat attcggaatt taaagtaagg aaaaacatgg ctaatatttt
     4141 aaaaacaatt atcgaaaatg ataaaggaga aatccgtcgt ctggaaaaga tggctgacaa
     4201 ggttttcaaa tacgaagacc aaatggctgc tttgactgac gaccaactaa aagcaaaaac
     4261 agttgaattt aaggaacgtt atcaaaatgg agaatcactg gattcattgc tttacgaagc
     4321 atttgcggtt gtccgtgaag gtgccaaacg tgtcctaggt ctcttccctt ataaggttca
     4381 ggtcatgggg gggattgttc ttcaccatgg tgacgtgcca gagatgcgta caggggaagg
     4441 gaaaaccttg actgcgacca tgccggtata cctcaatgcc ctttcaggta aaggggttca
     4501 cgtagttacg gttaatgaat acctgtcaga acgtgacgcg actgagatgg gtgaattgta
     4561 ctcttggctt ggtttgtcag tagggattaa cttggctacc aaatctccaa tggagaaaaa
     4621 agaagcctat gagtgtgata ttacttactc aactaactca gaaatcggat ttgactacct
     4681 tcgtgacaac atggtcgttc gcgccgaaaa catggtacaa cgtccgctta actatgcctt
     4741 ggtcgatgag gttgactcta tcttgattga cgaggctcgt acacctttga ttgtatcagg
     4801 tgccaatgcg gttgaaacca gtcagttgta tcacatggca gaccactatg taaaatcttt
     4861 gaacaaagat gactacatca tcgatgtgca gtctaagact attggtttgt ctgattcagg
     4921 gattgacagg gctgaaagct acttcaaact tgaaaacctc tatgacatcg aaaacgtggc
     4981 tttgactcac tttatcgata acgcccttcg tgccaactac atcatgcttc tcgatattga
     5041 ctatgtggtg agcgaagagc aagaaatctt gattgtcgac caatttacag gtcgtaccat
     5101 ggaaggtcgt cgttattctg atggattgca ccaagctatt gaagccaaag aaggtgtgcc
     5161 aatccaggat gaaaccaaga catctgcctc aatcacgtac caaaacctct tccgtatgta
     5221 caagaaattg tctggtatga cgggtacagg taagactgag gaagaagaat tccgtgaaat
     5281 ctacaacatt cgtgttattc caatcccaac aaaccgtcct gttcaacgta ttgaccactc
     5341 agaccttctt tatgcaagta tcgaatctaa gtttaaagcg gttgtcgaag acgttaaggc
     5401 tcgttaccaa aagggtcaac ctgtcttggt tggtacagta gcggttgaaa ctagtgacta
     5461 catttctaag aaattggttg cagctggtgt tcctcacgaa gtcttgaatg ccaaaaacca
     5521 ctatagagaa gcccaaatca tcatgaatgc tggtcaacgt ggtgccgtta ccatcgcaac
     5581 caacatggcg ggtcgtggta ccgacatcaa gcttggtgaa ggtgttcgtg aacttggagg
     5641 actttgtgtt attggtacag aacgtcatga aagtcgtcgt atcgataacc agcttcgtgg
     5701 acgttcaggt cgtcaaggag atccaggtga gtcacaattc tacctatctc ttgaagatga
     5761 tttgatgaaa cgttttggtt ctgaacgctt gaagggaatc tttgaacgct tgaacatgtc
     5821 tgaagaggcc attgagtctc gcatgttgac gcgtcaggtt gaagcagctc agaaacgtgt
     5881 cgaaggaaat aactacgata cccgtaaaca agtccttcaa tacgatgatg tcatgcgtga
     5941 acaacgtgag attatctatg ctcaacgtta cgatgtcatc actgcagatc gtgacttggc
     6001 acctgaaatt cagtctatga tcaaacgcac gattgaacgt gtcgttgatg gtcatgcgcg
     6061 tgccaaacaa gatgaaaaac tagaggcaat tttgaacttt gctaagtaca acttgcttcc
     6121 tgaagattct attacgatgg aagacttgtc aggcttgtct gataaggcca tcaaggaaga
     6181 gcttttccaa cgttccttga aggtttacga tagtcaggtt tcaaaactac gcgatgaaga
     6241 agcagttaaa gaattccaaa aagttttgat tctacgagtg gtggataaca agtggacaga
     6301 tcatatcgat gcccttgatc aattgcgtaa cgcggttgga cttcgtggct atgctcagaa
     6361 caaccctgtt gttgagtatc aggcagaagg tttccgtatg tttaatgata tgattggttc
     6421 gattgagttt gatgtgacac gcttgatgat gaaagcacaa attcatgaac aagaaagacc
     6481 acaggcagaa cgtcatatca gtacaacagc gactcgcaat atcgctgctc accaagcaag
     6541 tatgccagaa gatttggatt tgagccagat tggacgcaat gaactttgcc catgtggttc
     6601 tggtaagaaa tttaaaaact gtcacggtaa aagacaataa aatgagatag tttagaggcg
     6661 gatatcttgt gaaaagtaaa tttttactgg gtatccgttt gctttataag gagatgagtt
     6721 atggtattta cagcaaaaag ctctaaaata aatatagaag aagttcgtgc cttgtcaaaa
     6781 ttagaaggtc aggctttgga gaggaaatca cagagagatc aagagctaga agccattata
     6841 cgtggagaag accagcgaat tctcttggta atcgggccat gctcatctga taacgaagaa
     6901 gctgtccttg aatacgctaa gcgtttggca gtcctacaag aagaagtggc agatcgtatc
     6961 tttatggtta tgcgtgttta tactgccaaa ccccgtacca acggagatgg ctataaaggc
     7021 ttgattcacc agcctaacgc gacagaagcg cctagtctta tcaatggaat caaagccgtt
     7081 cgccatcttc actatcgtgt catcacagaa acagggatga caactgctga tgaaatgctt
     7141 tatcctgaaa accttccgct tgtagatgat ttgatttctt acatggcagt tggtgcccgt
     7201 tcagttgaag accagcaaca ccgctttgtg gcaagtgggg caggattttc tactggtttt
     7261 aaaaatccaa cctctggaaa tctcaatgtc atgtttaatg ggatttatgc tgctcaaaac
     7321 aaacaaagtt tccttttctt aggaaaagaa gtagaaacaa ctgggaaccc gctttcacac
     7381 gctattcttc gtggtgctct taatgagtat ggaaaaaata ttcccaacta ctattatgac
     7441 aatttaattg ataccattgc ccagtatgag aaaatgggct tggaaaatcc ttttatcatc
     7501 attgatacca atcatgacaa ttctggtaag cagtatattg aacagatccg aattgtccgc
     7561 cagaccttga ttaaccgtgc ttggaatgaa aaaattaagc agttcgttcg tggttttatg
     7621 attgagtctt atctagaaga tggtcgacaa aatgagccag aagtatttgg taagtctatc
     7681 acagaccctt gcctgggttg ggataacaca gaagctcttg tcagagaaat ttacaaaacg
     7741 ttaggagaat aagatggcat ttattgaaaa aggtcaagaa atcgatatgg aagtcatcaa
     7801 ggctgaaacc caattgtctg cggaagcctt gagactcaag gaaagccgtg acagggaatt
     7861 ggcagatatt atttcagggg aagatgaccg tattctcttg gtgattggtc cttgctcttc
     7921 tgataatgaa gaggcggtct tggaatatgc tcgccgttta tccgccttgc aaaagaaggt
     7981 agcggacaag attttcatgg tcatgcgcgt gtatactgct aagcctcgta ccaatggaga
     8041 cggctataaa ggattggttc accagccaga tacttctaag gctccaagcc tgattaacgg
     8101 cttgcaggct gtgcgccagt tgcactaccg cgtgattaca gagactggtt tgacaacggc
     8161 agatgagatg ctttatccgt caaatctgat cttggtggat gacttggtca gctaccatgc
     8221 cgttggagct cgttctgtgg aagaccaaga gcaccgcttt gtggcttctg ggattgatgc
     8281 accagtaggg atgaaaaatc caacctcagg aaatttgggt gttatgttta acgccatcta
     8341 tgctgctcaa aacaagcaaa ccttccttta tcatgggcag gaagttgaga catcaggtaa
     8401 tcctttggcc catgttatcc tccgtggagc agtcaacgag tatggcaatt atatgccgaa
     8461 ttactactat gaaaacctac tccaagccat tgaacgctat gaaaccatgg gacttgaaaa
     8521 tccttttatc ctcattgaca ccaaccatga taactcaggc aagcaatata tggagcagat
     8581 tcgaattgtt cgccagacct tgcagaatcg tgattggaat gagaaaatta aaaagacggt
     8641 tcgaggattt atgattgaat cttacctagc agatggtcgt caaaaccaac cagagatctt
     8701 tggttgctct attactgacc cttgcctagg ttgggaaaat acagaggcct tggtagaaga
     8761 gatttatgtt accttgacaa aataagtgaa aaggatggag ttggggaatc tcaactcctt
     8821 ttgatgagaa tgatagttgg acacggaatt gacatcgaag aattggcttc gatagaaagc
     8881 gcagttacac gacatgaagg atttgctaag cgtgtactga ccgctcagga aatggagcgc
     8941 ttcaccagtc tcaaaggacg caggcaaata gaatatttag ctggtcgctg gtcggctaag
     9001 gaggcctttt ccaaggctat gggaacgggc attagcaagc tcggttttca ggatttggaa
     9061 gtcttgaaca atgaacgtgg ggcgccttat tttagtcagg caccattttc aggaaagatt
     9121 tggctgtcta tcagccacac cgatcagttt gtgacagcca gtgtcatttt ggaggaaaat
     9181 catgaaagct agtccacata gaccaaccaa ggctctgatt catctgggag ctattcgaca
     9241 aaatattcag caaatggggg ctcatatccc tcaaggaacg ctcaagttgg ctgtggtcaa
     9301 ggccaatgct tatggtcatg gagctgttgc cgttgccaag gcaattcaag atgatgttga
     9361 tggcttttgc gtttccaata tcgatgaagc cattgaactc agacaagctg gactcagcaa
     9421 gccaatcctc attttaggag tttctgaaat cgaagctgtt gctctagcta aagaatatga
     9481 cttcaccttg acagtggctg gactggagtg gattcaagca ctcttagata aggaagtgga
     9541 cctaactgga ttgacagtcc acctcaagat tgattcaggg atgggacgga ttggttttat
     9601 agaggcaagt gaggttgagc aggctcaaga tttgctccaa caacacggtg ttcgtgttga
     9661 aggaatcttt acccactttg ctactgctga tgaggaatca gatgactatt ttaatgccca
     9721 gttagaacgg tttaaaacta ttttagctag tatgaaggaa gttccagagc tggttcatgc
     9781 tagcaattct gcaacgactc tttggcatgt agagactatt ttcaatgcgg ttcgtatggg
     9841 agatgccatg tatggtctca atccaagtgg agcggtcttg gatttgcctt atgatttgat
     9901 accggccttg accttggagt ctgctctggt tcatgtcaag acagttccag ctggagcttg
     9961 catgggctat ggagcaactt atcaagcgga tagcgagcaa gtcatcgcga ccgtgccaat
    10021 cgggtatgca gatggatgga caagagacat gcaaaatttc tctgtcttgg tagatggcca
    10081 agcttgccca attgttggca gggtttcgat ggaccaaatc actattcgat tgcctaagct
    10141 ttatccgcta ggaaccaagg taaccttgat tggctccaat ggggataagg aaatcactgc
    10201 aactcaggta gcgacctacc gcgtaaccat taactatgag gtggtttgcc tcctcagcga
    10261 ccgtattccg agagaatatt attagaaaag aaaggagtgg agcatgaatc tacatcaacc
    10321 cttgcatgtc ttgcctggtg tgggaccaaa gtcagcagaa aaatacgcca aactaggaat
    10381 tgaaaacttg caagatctct tgctctactt tcctttccgt tatgaagact tcaaaaccaa
    10441 gcaggtgctg gagctggaag acggtgagaa ggcagttctt tctggtcagg tagtgactcc
    10501 tgctagtgtc cagtattatg gtttcaagcg caatcgcctg cgttttagtc tcaagcaggg
    10561 agaggtcgtt tttgcggtga atttctttaa ccagccctat ctggctgata aaatagagtt
    10621 gggagcaacc cttgctgtct ttggaaaatg ggaccgcgct aaggctagtc tgactgggat
    10681 gaaggttctg gctcaggtag aagatgacct ccagcctgtt tatcgtctgg ctcagggaat
    10741 cagtcaggcc agtctggtta aggtcatcaa gacggctttt gatcagggac tggacctctt
    10801 gatagaagaa aatctgcccc agtctttact agacaaatac aaactcatgt cccgttgtca
    10861 ggcagtccga gctatgcatt ttccaaagga tttggcagaa tacaagcagg ctcttcgccg
    10921 tataaagttt gaggaactct tttatttcca aatgcagctg cagacgctca agtctgaaaa
    10981 tagaattcag ggaagtggtc tggttctgga ttggtctcag gaaaaagtga cagcagttaa
    11041 agcaagtctt ccttttgccc tgacccaagc tcaggaaaag agtttgcagg aaattttaac
    11101 tgatatgaag tccgaccacc acatgaatcg tctcctacaa ggggatgtgg ggagtggaaa
    11161 aacggtagtc gctggcttgg ccatgtttgc ggcagtgaca gcaggttatc aggctgccct
    11221 aatggtacca acagaaatcc tcgcagagca acactttgag agtttacaga acctttttcc
    11281 caatttgaaa ctggctctct tgacaggttc cttgaaagct gcagaaaaga gagaagtctt
    11341 ggagaccatt gccaagggtg aggctgattt gattatagga actcacgctc tgatacaaga
    11401 tggggtggag tatgctcgtc ttggtttgat tattatcgat gagcagcacc gttttggtgt
    11461 agggcaaagg cgtattttac gggaaaaagg tgacaatcca gatgtcctca tgatgacggc
    11521 gactcccatt ccacggacgc ttgccatcac agcctttgga gatatggatg tttccattat
    11581 cgaccagatg ccagcaggtc ggaagcctat tgtgacgcgc tggatcaaac atgagcaact
    11641 acctcaggtc ttgacttggt tagaggggga aattcaaaaa ggttcccaag cctatgtcat
    11701 ctctcctttg attgaagaat cagaagctct agatttgaaa aatgccattg ccttatcaga
    11761 agagctgacg gctcattttg caggcaaggc agaggtggct cttctacatg gtaggatgaa
    11821 gagtgacgaa aaagaccaga tcatgcagga tttcaaggag agaaagacgg atattctggt
    11881 ttcgacgacg gttattgagg ttggggtcaa cgttcccaat gcgactgtca tgattatcat
    11941 ggatgccgat cgcttcgggc tcagccagct tcaccagctt agaggtcgtg tcggtcgggg
    12001 ggacaagcag tcctacgctg ttctcgttgc caatcccaag acggattctg ggaaagaccg
    12061 catgcgcatc atgacagaaa cgaccaatgg atttgtcctt gcggaggaag atttgaaaat
    12121 gcgtggttct ggtgagattt ttggaaccag acagtcagga cttccagagt tccaagtggc
    12181 tgatattatc gaagattttc cgattttaga agaagcaaga aaggttgcta gctacattag
    12241 ttctatagaa gcttggcaag aagatccaga gtggcgcatg attgcccttc atctggaaaa
    12301 gaaagaacat ctggattaag ctttctctaa ggaaaactta agctagtttt taggtttggc
    12361 tcttatacta aagtcatcaa aaagaaacga ggactctcat atgacagtaa cgattaaagt
    12421 aaattaccaa accactttcc aaaagaagga agcaaaaaac tagtataaac agaagagaga
    12481 gcgaaatgct ctttttcgtt tctaaaacta ctttcagccc atcatcctaa aagtaaagaa
    12541 tctaaattca ctttctattt atccttcttt cttgcattga ttacatagat atgctacagt
    12601 tgtggtaacg attacaaaat aaaaggagca tgctatgaaa aatccagctt tgctagaaga
    12661 aattaagacc tatagaggaa gggatgaggt tccggaagac tttgatgctt tctgggatgg
    12721 ggaagtaaaa aatgtttcca cgcttccatc ctaccacttg gaggaaagag atttccacat
    12781 tcctcaagtc aagtgctatg agttaacatt tgaaggaagc aaggaaggaa aggtctatgc
    12841 acgcattgtt cttccaaaga gtgaggagaa ggttccacta atattccatt ttcatggtta
    12901 tatgggacgt ggctgggact gggccgacat gctgggcttc accgtagctg gttacggtgt
    12961 tgtttccatg gatgtgcggg gccagtcagg ttactcacaa gacggcttgc gttctccttt
    13021 aggaaatacc gtgaaggggc atattatccg tggtgctatg gaaggtcggg accacctctt
    13081 ttataaggat gtttatctgg atatttacca gttggtcgaa attgttgcta gtctgtctca
    13141 ggttgatgag aagcgtcttt ctagctatgg tgcctcacaa ggaggggctc tagctctagt
    13201 tgcagcagcg ctcaatcctc gaattcagaa aacagttgcc atttatccct tcttgtcaga
    13261 cttcagacgg gtgattgaga ttggtaatac tagcgaggct tacgacgaac ttttccgtta
    13321 tttcaagttt cacgacccct tccatgaaac agaggaggaa atcatggcga cccttgccta
    13381 tatcgatgtc aaaaatcttg cccatcgtat ccaaggtgag gttaagatga ttacgggctt
    13441 ggacgacgat gtttgctatc ccattaccca gtttgcgatt tataatcgtc tgacctgcga
    13501 taaaacctat cgcatcatgc ctgagtatgc tcacgaagcc atgaatgtat ttgtcaatga
    13561 ccaagtctac aactggctct gtggaagtga gattcctttt aaatatctaa aataaggagt
    13621 cgactctaag cacaaaatct taaaaattac aaacacgcat agtatcaggg gattaaaaaa
    13681 acttgatact atgcgtttta tcatggaaat atagtaaaat gaaacaagaa taggacaaaa
    13741 cgatcaggac agtcaaatcg atttctaaca atgttttaga agcaaatgtg tactattcta
    13801 gtttcaatct attatattta tagaattttt tgttgctaga tttgtcaaat tgcttaaaat
    13861 aatttttttc agaaagcaaa agccgatacc tatcgagtag ggtagttctt gctatcgtca
    13921 ggcttgtctg taggtgttaa tacttttcaa aaatctcttt aaaccacgtc agcttcgcct
    13981 tgccgtatat atgttactga cttcgtcagt tctatctgcc acctcaaaac ggtgttttga
    14041 gctgacttcg tcagttctat ctgccacctc aaaacggtgt tttgagctga ctttgtcagt
    14101 cttatctaca acctcaaaac agtgttttga gcatcatgcg gctagcttct tagtttgctc
    14161 tttgattttc attgagtata aaaacagatg agtttctgtt ttctttttat ggactataaa
    14221 tgttcagctg aaactacttt caaggacatt attatataaa agaatttttt gaaactaaaa
    14281 tctactatat tacactatat tgaaagcgtt ttaaaaatga ggtataataa atttactaac
    14341 gcttataaaa agtgatagaa tctatcttta tgtatattta aagatagatt gctgtaaaaa
    14401 tagtagtagc tatgcgaaat aacagataga gagaagggat tgaagcttag aaaaggggaa
    14461 taatatgata tttaaggcat tcaagacaaa aaagcagaga aaaagacaag ttgaactact
    14521 tttgacagtt tttttcgaca gttttctgat tgatttattt cttcacttat ttgggattgt
    14581 cccctttaag ctggataaga ttctgattgt gagcttgatt atatttccca ttatttctac
    14641 aagtatttat gcttatgaaa agctatttga aaaagtgttc gataaggatt gagcaggaag
    14701 tatggtataa atagcataag ctgatgtcca tcatttgctt ataaagagat attttagttt
    14761 aattgcagcg gtgccctggt agataaacta gattggcagg agtctgattg gagaaaggag
    14821 aggggaaaat tggcaccaat ttgagatagt ttgtttagtt catttttgtc atttaaatga
    14881 actgtagtaa aagaaagtta ataaaagaca aactaagtgc attttctgga gtaaatgtct
    14941 tatttcagaa atcgggatat agatatagag aggatcagta tgaatcggag tattcaagaa
    15001 cgtaagtgtc gttatagcat taggaaacta tcggtaggag cggtttctat gattgtagga
    15061 gcagtggtat ttggaacgtc tcctgtttta gctcaagaag gggcaagtga gcaacctctg
    15121 gcaaatgaaa ctcaactttc gggggggagc tcaaccctaa ctgatacaga aaagagccag
    15181 ccttcttcag agactgaact ttctggcaat aagcaagaac aagaaaggaa agataagcaa
    15241 gaagaaaaaa ttccaagaga ttactatgca cgagatttgg aaaatgtcga aacagtgata
    15301 gaaaaagaag atgttgaaac caatgcttca aatggtcaga gagttgattt atcaagtgaa
    15361 ctagataaac taaagaaact tgaaaacgca acagttcaca tggagtttaa gccagatgca
    15421 tcagctccac gcttttacaa tctcttctct gtatccagtg acaccaagga aaatgagtac
    15481 tttactatgt cggtccttga taatacagct cttattgaag ggcgtggcgc taacggagag
    15541 cagttctatg ataagtatac agatgctcct ttgaaagttc gcccaggaca atggaattcc
    15601 gtgaccttta ctgtcgaaca accgacagcg gagttacctc atggacgagt tcgtctctat
    15661 gtgaacggtg tcttatctcg aacaagtctc aaatctggta actttatcaa agatatgcca
    15721 gatgttaatc aagctcaact tggagcaacc aaacggggca ataagacagt ttggggaagc
    15781 aatctacaag ttcgaaacct aaccgtctat gatcgtgcct taagcccaga agaagttcag
    15841 acgagaagcc aactatttga aagaggtgat ttggagaaga aacttccaga aggtgcgaaa
    15901 atctcagaga aagaagacgt ctttgaaggg ggaatgaaca acaaaccaaa taaagatgga
    15961 attaagagtt atcgtattcc agctcttctc aagacagata aaggaactct gattgcaggt
    16021 gcagatgaac gccgtcttca ttctagtgac tggggtgata tcggtatggt tatcagacgt
    16081 agtgaagaca atggtaaaac ttggggagac cgagtaacca ttaccaactt acgtgacaat
    16141 ccaaaagctt ctgatccatc gatcggttca ccagtgaata tcgatatggt gttggttcaa
    16201 gatcctgaaa ccaaacgaat cttttccatc tatgacatgt tcccagaagg gaagggaatc
    16261 tttggaatgt cttcgcaaaa agaagaagcc tacaaagaaa ttgacggaaa aacctatcaa
    16321 atcctctatc gtgaaggaga aaagggagct tataccattc gtgaaaatgg tactgtctac
    16381 acaccagatg gcaaggcgac agactatcgc gttgttgtag atcctgttaa accagcctat
    16441 agcgacaagg gtgatctata caagggtgac caattactag gtaatatcta cttcacaaca
    16501 aacaaaactt ccccatttag aattgccaag gatagctatc tatggatgtc ctacagtgat
    16561 gacgacggga agacatggtc agctcctcaa gatattactc cgatggtcaa agccgattgg
    16621 atgaaattct tgggtgtagg tcctggaaca ggaattgtac ttcggaatgg gcctcacaag
    16681 ggacggattt tgataccggt ttatacgact aataatgtat ctcacttaaa tggctcgcaa
    16741 tcttctcgtg tcatctattc agatgatcat ggaaaaactt ggcatgctgg agaagcggtc
    16801 aacgataacc gtcaggtaga cggtcaaaag atccactctt ctacgatgaa caataaacgt
    16861 gcgcaaaata cagaatcaac ggtggtacaa ctaaacaatg gagatgttaa actctttatg
    16921 cgtggtttga ctggagatct tcaggttgct acaagtaaag acggaggagt gacttgggag
    16981 aaggatatca aacgttatcc acaggttaaa gatgtctatg ttcaaatgtc tgctatccat
    17041 acgatgcacg aaggaaaaga atacatcatc ctcagtaatg caggtggacc gaaacgtgaa
    17101 aatgggatgg tccacttggc acgtgtcgaa gaaaatggtg agttgacttg gctcaaacac
    17161 aatccaattc aaaaaggaga gtttgcctat aattcgctcc aagaattagg aaatggggag
    17221 tatggcatct tgtatgaaca tactgaaaaa ggacaaaatg cctataccct atcatttaga
    17281 aaatttaatt gggaattttt gagcaaaaat ctgatttctc ctaccgaagc gaaagtgaag
    17341 cgaactagag agatgggcaa aggagagatg ggcaaaggag ttattggctt ggagttcgac
    17401 tcagaagtat tggtcaacaa ggctccaact cttcaattgg caaatggtaa aacagcgact
    17461 ttcctaaccc agtatgatag caaaaccttg ttgtttgcag tagataagga agatatcgga
    17521 caggaaatta ttggtatagc taaaggaagc atcgaaagta tgcataatct tcctgtaaat
    17581 ctagcaggtg ccagagttcc tggcggagta aatggtagca aagcagcggt gcatgaagtt
    17641 ccagaattta cagggggagt taatggtaca gagccagctg ttcatgaaat cgcagagtat
    17701 aagggatctg attcgcttgt aactcttact acaaaagaag attatactta caaagctcca
    17761 cttgctcagc aggcacttcc tgaaacaggg aacaaggaga gtgacctcct agcttcacta
    17821 ggactaacag ctttcttcct tggtctgttt acgctaggga aaaaagagag aacaataaga
    17881 gaagaattct aaacatttga ttttgtaaaa atagaaggag atagcaggtt ttcaagcctg
    17941 ctatcttttt ttgatgacat tcaggctgat acgaaatcat aagaggtctg aaactacttt
    18001 cagagtagtc tgttctataa aatatagtag attgaaataa gatgtgaaca actctatcag
    18061 gaaagtcaaa ttaatttata gaaaaatttt agcagtcaag gtgtactgtt atagattcaa
    18121 tatattatgt gactattaat cttgtcttct cctaaaattg actttcttgt tttcttatct
    18181 tgtccactcg aaacaagtat tgtaagaatt tgatt
//
LOCUS       DAVMJI010000039        17605 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.039, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000039 DAVMJI010000000
VERSION     DAVMJI010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17605
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.039"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(184..1806)
                     /gene="groL"
                     /locus_tag="VYR58_001716"
     CDS             complement(184..1806)
                     /gene="groL"
                     /locus_tag="VYR58_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV3622832.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISNRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1822..2106)
                     /gene="groES"
                     /locus_tag="VYR58_001717"
     CDS             complement(1822..2106)
                     /gene="groES"
                     /locus_tag="VYR58_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV3622833.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2376..2771)
                     /locus_tag="VYR58_001718"
     CDS             complement(2376..2771)
                     /locus_tag="VYR58_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV3622834.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2848..3609)
                     /locus_tag="VYR58_001719"
     CDS             complement(2848..3609)
                     /locus_tag="VYR58_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV3622835.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTHCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(3642..4268)
                     /locus_tag="VYR58_001720"
     CDS             complement(3642..4268)
                     /locus_tag="VYR58_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV3622836.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVACLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPVKHWTA"
     gene            complement(4284..4601)
                     /locus_tag="VYR58_001721"
     CDS             complement(4284..4601)
                     /locus_tag="VYR58_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV3622837.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4598..4897)
                     /locus_tag="VYR58_001722"
     CDS             complement(4598..4897)
                     /locus_tag="VYR58_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV3622838.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            4985..5065
                     /locus_tag="VYR58_001723"
                     /pseudo
     CDS             4985..5065
                     /locus_tag="VYR58_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(5194..5385)
                     /locus_tag="VYR58_001724"
     CDS             complement(5194..5385)
                     /locus_tag="VYR58_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV3622839.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5546..6220)
                     /locus_tag="VYR58_001725"
     CDS             complement(5546..6220)
                     /locus_tag="VYR58_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622840.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKIVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(6226..6672)
                     /locus_tag="VYR58_001726"
     CDS             complement(6226..6672)
                     /locus_tag="VYR58_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV3622841.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6786..7289)
                     /locus_tag="VYR58_001727"
     CDS             complement(6786..7289)
                     /locus_tag="VYR58_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV3622842.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7286..7648)
                     /locus_tag="VYR58_001728"
     CDS             complement(7286..7648)
                     /locus_tag="VYR58_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV3622843.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7714..9573)
                     /locus_tag="VYR58_001729"
                     /pseudo
     CDS             complement(7714..9573)
                     /locus_tag="VYR58_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(9612..10061)
                     /locus_tag="VYR58_001730"
                     /pseudo
     CDS             complement(9612..10061)
                     /locus_tag="VYR58_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(10185..10901)
                     /locus_tag="VYR58_001731"
     CDS             complement(10185..10901)
                     /locus_tag="VYR58_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV3622844.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11782..13197)
                     /gene="ply"
                     /locus_tag="VYR58_001732"
     CDS             complement(11782..13197)
                     /gene="ply"
                     /locus_tag="VYR58_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV3622845.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13208..13540)
                     /locus_tag="VYR58_001733"
     CDS             complement(13208..13540)
                     /locus_tag="VYR58_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622846.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTGIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13611..14219)
                     /locus_tag="VYR58_001734"
     CDS             complement(13611..14219)
                     /locus_tag="VYR58_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622847.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14232..14690)
                     /locus_tag="VYR58_001735"
     CDS             complement(14232..14690)
                     /locus_tag="VYR58_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV3622848.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14815..15211
                     /locus_tag="VYR58_001736"
                     /pseudo
     CDS             14815..15211
                     /locus_tag="VYR58_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15952..16212)
                     /locus_tag="VYR58_001737"
     CDS             complement(15952..16212)
                     /locus_tag="VYR58_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622849.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(16271..16822)
                     /locus_tag="VYR58_001738"
     CDS             complement(16271..16822)
                     /locus_tag="VYR58_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622850.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(16812..17009)
                     /locus_tag="VYR58_001739"
     CDS             complement(16812..17009)
                     /locus_tag="VYR58_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622851.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(17013..17597)
                     /locus_tag="VYR58_001740"
     CDS             complement(17013..17597)
                     /locus_tag="VYR58_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622852.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
BASE COUNT         5240 a         3954 c         3145 g         5266 t
ORIGIN      
        1 aactttgaaa acttcaaaaa acggattttc atcgctctga atatcaaaaa agaaaggaca
       61 aaatttgtcc tttctcgagc ttagcttttc ttcaacccac tacagttgac aaagagccta
      121 taaaaagaag ggttagtcat tccctccttt tgtgtttttt ataagttgtt ttctatagaa
      181 agcttacatc atcccgccca tcatacttgg atccattgct ggagctgggg ctactggttc
      241 tggtttattg gctacgactg cttctgttgt caaaatcaag ctggctacag atgctgcatt
      301 ttgtagggct gaacgactca ctttaactgg atcaatgata ccttgatcaa tcatgttaac
      361 ccactcgcca gttgctgcgt tgaatcctat accaagctca gcatttttca aacgatcgat
      421 aacgatagat ccttcaaatc ctgcattgtg agcaatttga cgaacgggtt cttccaaagc
      481 acggagaaca atattacgtc ctgttgcttc atctcctgtc aattccaagg tagcaacagc
      541 tggaatcaca ttggcaagag ctgttccacc acctgcaaca ataccttctt caacagctgc
      601 acgagtagcg ttgagggcat cttcaatgcg gagtttcatt tctttcaact cagtttcagt
      661 tgcggctccg accttaataa ccgctacacc acctgacaat ttggccaagc gttcttgcaa
      721 tttttcacgg tcaaattcag aagttgtagt ttcgatttga gacttgataa ccgcaacacg
      781 gttagaaatc gcttcaggat ttcctgcacc ttctacaata accgtgctat ctttgtccac
      841 ggtcactctc gctgcttgac caagagcttc aattgtcgca tctttcaact caagaccaag
      901 gtcttctgtg ataactgttc cgcctgttaa gatggcgata tcttcaagca tggctttgcg
      961 acggtcacca aaaccaggtg ccttgactgc tactacgttg aaggttccac gaatcttgtt
     1021 caaaacaaga gttggaagag cctcgccatc cacatcatcc gcaataatca agagtggacg
     1081 attgctttgg agaatgcttt ccaaaagtgg caagatttct tggatattgg aaattttctt
     1141 gtctgtaatc aaaatgtacg gattttcaag gtcagccacc attttttcgc tatcagtcac
     1201 catgtactgt gaaaggtaac cacggtcaaa ctgcattcct tctacgactt caagctctgt
     1261 ttccatacca cgtgactctt cgatggtgat gacaccgtct ttgccaactt tttccattgc
     1321 ttcagagatg tactcaccaa ctttttcaga acgagaagat acggctgcaa cttgagcgat
     1381 agcttcttta ttggcaacag ggatggcgtt gtttttcaaa gcttcaactg ctgcggcaac
     1441 tgctgtttca atcccacgac gaataccgat tggatttgca cctgctgtga cgtttttgat
     1501 tccttcacgg acgatagctt gggtcaagac tgttgcagtc gtagtcccgt cacctgcgat
     1561 atcattggtt ttagaagcta cttctgatac taacttagca cccatatttt caaaatggtc
     1621 ttccaattcg atttctttgg caatggtcac accgtcattg gtaatcaagg gtgaaccgaa
     1681 tgacttttca agaacgacat tgcgaccttt tggtcccaag gttactttaa cagtgtctgc
     1741 aagaatatcg acaccacgaa ccatggctga acgggcatct gatgaaaatt taatttcttt
     1801 tgacatactt actttctcct tctattcctc aatgattgcc aaaatgttag cttcgcctac
     1861 gataatgtac ttttcatcgc catctttgac atcaagacct gcgtgggctt caactaagac
     1921 acgatctcca gttttaacac ttggagcaac caagtcaccg ttcaaggtac gaacaccttg
     1981 tccagtagcc acaacttgag ctgttttggt tttttcttgg gctgagcctg caaggacaaa
     2041 gcccccaacg gtttgttctt tttcttctat ttttaagacc acacggtccc ctaatggttt
     2101 caacatctga tttcctccat aatgagatag atattattag cactctttga actggagtgc
     2161 taattcataa ttctattgta tcacttggtc agaaatagtc aagaaaaaag tctgactttc
     2221 tcaagataaa aagcctgaga ccaactcaga ctttttaatg tttatactca atgaaaatca
     2281 aagagcaaac taggaagcta gccgcaggct gctcaaagca ttgctttgag gttgtggata
     2341 aagctaacgt ggtttgaaga gattttcgaa gagtattaaa atggcaattc ttcctcttcc
     2401 aagaccaaat ctgccaaatc ttggcctgca ttattttcac gcatggcacg ttgagcacga
     2461 ctttctaaga gttggaatcc tgtcacaagg acttcggtta catagttcat ctgaccattt
     2521 ttctcaaagc gacgggtacg caattctcca tcaacggaaa tgagactacc tttggttgcg
     2581 tagcttgcca aagtttctgc tagtctgccc cataggacca tattgacaaa atcagcttca
     2641 cgttcaccgt tttggtcttt gtaacgacgg ttgacagcga tagttgctcg cgctaccgac
     2701 ttgtcattgt tggttttgtg caattctggt gtagacgtta aacgcccaat catgataact
     2761 ttattataca tattttcttc ctcctactta tctattcgta ggaaatcaaa aaagttacag
     2821 aaatttgtaa cttttcgagg aaatttctta ttttttatga atcatgaaac ctgtcgcctg
     2881 ttgattggcc ataatggtca tatctgtaat ctgaacacgg cgaggctgac tggtcacata
     2941 gactactgtg tctgcaatat cctgagcttg caaggcttct attccttggt aaacggacgc
     3001 agcccgctct ttatcaccat gaaaacgaac agttgagaaa tctgtttcga caatcccagg
     3061 ctgaatggtt gtcaccttga tatccgttgc gatggtatca attcgcagtc catccgaaaa
     3121 ggtcttaacc gctgccttgg tagctgagta aacagcggca ccagcatagg cgtagattcc
     3181 tgcggttgac cccatattga taatatgacc ttgattgact tttatcattg ctggcaagaa
     3241 acagtgagta accgccatca gacctttaac attggtatcc aacatggtca acatatccaa
     3301 ctcctcatag tcttgatagg gagccaagtc aagagccagt ccggcgttgt tgaccaagat
     3361 atcaatcctc cctatcgttt ctagaatatc agagcaaaca gtcttcacca tgaccatatc
     3421 cgtcacatct agtggaaaag tccagacggt ttgatttgga aagcttactg caaactccga
     3481 cttgaggatt tctaatctgt ctatccgtcg tcctgttaga acgacatcct caccctgctc
     3541 cagataagca cgcgcaatcg cttcaccgat tcctgaggtt gctcccgtaa tcactacatt
     3601 ttttgccatc ttatttcctt ctatcagatg ctgacaagtt cctaggcagt ccagtgtttc
     3661 actgggtcga acggtgttcc gacaacttgg tcttctgata attcaagcac cccacgtttt
     3721 tgcggagcat ttggcaaatg caattcacga ggactacaca tcatcccaaa actcttttca
     3781 ccacgaagtt cgcctgggaa aatgaaattc ccttttggca tcatggcacc aggaagagcc
     3841 acaatggttt tcaacccaac acgcgcatta ggtgctcctg caacgatttg cactatcttg
     3901 tcacttgcga ctgcaacttg gcagatgttg aggtggtcac tatctggatg ggctaccatc
     3961 tcaacaattt caccaacaac aaacttaggt tccttgtcat tgacaatttc ttctgtaaaa
     4021 ccttccgcct gtaattcttg gttcaaacaa gcgacttgct catctgataa aaagacttga
     4081 cctcgctctg caatttcaaa caagctcgaa acctcaaaaa tgttccaagc tactgtttcc
     4141 ccattttctt tgaggaaaac acgggctacc ttgcctttgc gttccacatt cagtttggca
     4201 tctccgctat ttttcacgat gaccataagg acatcaccga catgttcttt gttatatgta
     4261 aaaatcattg tttacttttt ctcctatttc aatcctgcta aaaaatcgtt aatttgctcc
     4321 ttacttttac ggtcgcgatt gacaaaacgg ccgatttcct tgtccttttc tagaacaaca
     4381 aggctaggaa ttccgtaaac atcccagagt ttggccaaat ccatatactg atctcggtcc
     4441 attcgaataa aggtgaactc tggattggtc tcctcaatct ctggtaaggc aggatagata
     4501 taacggcaat cgccacacca gtccgccaca aaaaggaaga ccttcttacc gtctttttct
     4561 actaaagatg ccaattcttc taaacttgct ggttgtatca taagacttcc tcctcataga
     4621 ctaggtcttc attttcatag acaaaagtat aatgacggcc atcctcaaaa atgacgccac
     4681 caagcaagct ctctagactg ctttcataga cttgaacata gagggtcgca atttccccca
     4741 tgtctgaaaa atggtctcgt acaatcgctg tcaactcttc ctgagtcttc atgagcttat
     4801 ggtcatctgc aacttttttc gtagcaaggg caaggctccc aataccaagc agagccagac
     4861 ctgccatcca cattttttta gctttcatac cattcatttt aacacaaaaa aggctttagg
     4921 acaaatgagg aaacagcaaa aaagcaagta aaaagcctct tcctttaagg aaaaggactt
     4981 cttatactca atgaaaatca aagaccaaac tagaaagcta gccgcaggct gctcaaaaca
     5041 cggttttgag gttgtagata aggcgacgct gacgtggttt gaagagattt tcaaagagta
     5101 ttattcttat tgccaggcac ctaagttgcc aacgtagtaa ccatcaggtg tgtaggtatt
     5161 gcgaagcatc ttacctgatg aagccagata atactacttg ccattgtctt tgacccaatc
     5221 attcgcaatc atggaaccag aagaacttac ataataccat tctcccttgt cataaaccca
     5281 agtactgact ttcatggttc ctgagcaatt aaaggcaaaa aaactgtcca atatcattcg
     5341 ttttttaaaa gcatttgaca ctacatcatc tacgctgtag tacatagata catcaaacgt
     5401 aaaagccaaa atatcgaaaa atatacaact tttaaaggca gcatttcatt ttttaaagtc
     5461 taacaaccat agaactgaaa tcagagcaag gcatcaattt cctactctta gtacgtctat
     5521 tttgatggtt gaagtgaaga tttttttatt taacgtagac aatttccaac ttcccaaaag
     5581 ccacatctcc acggatagtc aaggttttgc tggttggggc tacaggagcg tcagccttag
     5641 ctgcaccaaa ggaggtttct actttcaaat ctacacgcca gtgttgtgga acatagacgg
     5701 ttgcatttcc gaaggccact tcaatattta aagttgcaaa atcacctagc atctctgcat
     5761 tatcatagta gattttagca tccccaaaag cgacttccac ttggtcatct acgagatctt
     5821 gatcttgctt atagaaggtc ccgctaccaa aagcgacttc cttatccgtg acgactattt
     5881 ttttcccatt gtaccaccat tttttttcat tccagaactt acttgaatgc gtcagataac
     5941 caacaccaag taccaccaag atgctagccc aaataagaga atgattggta actggtaaca
     6001 agtcataagc gtaatttgca atgatgagcg ccagtaaacc tgtaaaaact gccgaagtga
     6061 gatgacgtct aaggatggac tcaatggact tataagcaaa aaaaacaata cctagtaaag
     6121 gccatatttt accatccaaa gaaggaattc caaaattccc ttgcagcaag atccaagctg
     6181 ctaaaaccaa taaaacaata ccaaatgctt tctttttcat gttttttacc tcatgtttct
     6241 tagattttct tttaggaggg attggtaatg ccgtgagaca tgaacctcct tgtgcgtctg
     6301 ataaaaggaa atggtgcccg ttcctgaaaa ggacttgtcc actgagtaaa tctgacggat
     6361 gtttgcgatc gttgacttgg aaactcgatt aaaatagcga ggcaagatag actccaactc
     6421 atagagcttg aggcgaacct cataagcttc cttctggtta tgagcgtaga tcttgctccc
     6481 ttctgtttca aagaagagaa tttctgacag gtctagataa tattcacctg tccccttgta
     6541 aaaagtcaac ctcggagcct ttgactcttg caagagccgt tgcaagtctg caatttcatc
     6601 tgtcaaagtg ggggtcttga tgacaatttc agtctcctct aaattgccgt caatctcaat
     6661 tcgtaacttc atcacatctc ctttctgact ctactatatc aaagctaagt taggaataca
     6721 agggcaaaaa agcaagtggt caatttgaag cagtaagtgg ttgtaggact agcttaactt
     6781 acatgtcaga ataggaagaa aaggaatccc cacaccaaac cacaagcata gccaaccaag
     6841 acatccttgg gataatgaac accccctaaa accctcacca accccagcaa agctgaaaag
     6901 atcaagcata ctaagccaat aggtagacta gcatgcagac aggccatgga gatgatagtt
     6961 gccgaaaaga catggcgact gggcatcgac cgtcccgaac tatccttatc aagaagggga
     7021 cagatatccc aagtttcata aggtctcggg tgattgattt tcttacgaaa cagggacaag
     7081 gtcacaaaac ctgatgcagg aataagcaca taaaccccaa cttgctgacc aagtcctagt
     7141 tgcaggtaag tggtgactag caagatcaga tagaccaggg gcatggcgac tgtcatcaaa
     7201 cgattgaaac tgcgtaatag gaataaaaga attggacgac tagttagtct ggagctgata
     7261 tttcgatacc attcttgata atttttcatt tatgcttctc atacttttct agaacttgtt
     7321 gagatgtttt ccccttggca agccaatcca ctagcttgtc caagcgacgt atttcctgca
     7381 tcagaggatc atcaatttcc tcaatacgga caccgcaaat cttccctgta attgcaattc
     7441 gttcagggac ataatatggt gcttgtctaa aaaaatctcc gtaagtaaca tccctatcca
     7501 gacaagcaag aacatcactc acttcatacc ctgtcaacca actggtcact tggtgaactg
     7561 actctgcctt tccacccttt cgctcaactt ttgcaatcaa ggctaagtag acagcagcaa
     7621 atttcatatt gtataatttc tgactcatac ttctctcttt ctatgtgtac tagtataaat
     7681 aagaaaaaga aggccgtcaa gccttctttt gatttattct tctgcttcat cttctgtaaa
     7741 ttgactattg tacaagtcag cgtagaagcc accttgcgcc atcagttcct catagttgcc
     7801 ttgctcgatg atatttccat ctttcatgac caagatcaag tctgcatttc ggatggttga
     7861 caagcggtgg gcaatgacaa aggatgtgcg tcattccatc aaacggtcca tggctttttg
     7921 gatcaattcc tctgtccgtg tgtcaacaga agaagtcgcc tcatccaaaa tcaaaagcgg
     7981 tgcatcctta agaagggcac gagcaatagt caatagttgt ttttgtccta cagacaaggt
     8041 cacggtgtca tccaagatgg tatcatagcc atctggcaag gtcataataa agtggtgaat
     8101 tcccacagcc ttactagctt ccatcattcg ttcatcacta atccctattt gattatagat
     8161 gagattgtct cgaatagttc cttcaaagag ccaggtatcc tgcaagacca ttgaaaaggc
     8221 atcatgcact tctgaacgcg tcatagcctt ggtatccaca ccatcaatgt gaatacttcc
     8281 cttatcaatc tcatagaatt tcatcaaaag attgacaatg gttgtcttac cagtcccagt
     8341 cggcccaaca atggcaacct tttgaccagc atgagctgtc gcagagaagt catagtcttg
     8401 aacattgaca ccgtccacca gaatttctcc tgctgacacg tcgtagaaac gtggaatcag
     8461 attgaccaga gttgatttac cagaacctgt tgacccaata aaggccactg tttgaccagt
     8521 ttctgcttta aagctaacat gttcaataac tgcctccgaa tttgccgcat agcggaaggt
     8581 cacatcctta aactcgacct gacctttgaa gttttcatca gtcagctgca cttgaacagg
     8641 gttttggata gaagaatgca aatctaaaac ttgattaatc cgcttagcag agaccatagt
     8701 tcggggaaga acgatgaaga gtgctcccat gagaaggaag cccatgacaa cctacatggc
     8761 ataagacatg aaaacaatca tgtcactaaa gagaggcaga cgcgctatcg aagcagcgtc
     8821 gttaatcaca taggccccaa tccagtaaat cgctacactc aaaccacttg aaatccccat
     8881 catgatagga ttcaaaatag ccataagacg gttgacaaac aaattcaaac gggtcaattc
     8941 atcatttact gctgcaaatt tttcattttg ataatcctct gcattgtagg cacgaacgac
     9001 acgaatacct gttaaactct cacgagtgat actgttcagt ttatctgtca acccctgaat
     9061 caaggactgt tttggaaagg ctagcgtcat caaaacggtc gtcatcagga cgttgacaat
     9121 cactaccaca agtacggccc agagtcagta ttctgaatga cctaaaatct tcccaatagc
     9181 ccagatagcc ataattggac cacgcgttac cacttgcaag cccatagtaa tcaacatttg
     9241 aacttgagta atgtcattgg tagtacgcgt caagaggcta ggaattgaaa atttcttaat
     9301 ctctgtctgc gagtaatcca aaactcggtt aaaaatatca cttctcagcc tactagtata
     9361 agaagccgcc actcgggatg caaaaaatcc aactgcaact acggacaaga aggcaagaaa
     9421 gagcattccc atcatcatgc ttgccggctg ccacaactca tctaaattag tttcttgact
     9481 acctagcaaa tccgtaattt tcgagatata ggtcggcact tccaactcta gatagaccga
     9541 aaagcaagta aagagaatgg ctagtaaaat catcccccat tcttttctac taattctttt
     9601 ggttaatttc tttattctct cctcctattc ccttgatatt ttgcctgtag ttgaccgaga
     9661 actttctcaa aaatcagtaa ttcatcttca tcaatgtctt ccatcaactg cttgtctatg
     9721 cgttcaaaaa aagccttaac ctgttgcatc tgagaacgtg ctttgtccgt cagacgaaca
     9781 aacttagccc gcttatcaac aggactcgcc tccaattcca ccaaaccatt ttgcactata
     9841 cgcttaacca gattactagc aacagacttg gtaatattga gttcctgctc gatatcttta
     9901 atcaagacca agtcttggtt tttctagcga ttatccaaaa aacgcacaac ctgaccttgc
     9961 ggcccaccca taaattcaat gccgcaacgt ttggcttcct tttgcaccat caggtgaatt
    10021 tgatgaccaa aacgcttaaa gactaacatc ggtttatcca taatctcccc cttctaaata
    10081 aaaatagttc tctggagaat aattaaattt ctatgagaac tattttcttg attaaaaaaa
    10141 tcccaagtga ttttctcact taggatcatg ttctataggt taaattaaaa cccatctacg
    10201 ttcgtataaa tcttttggac gtcttcgtcg tcttcaagaa cgctgtaaag tttttcaaag
    10261 gtttcaaggt cttcgcctga caattccact tctgactgag gaatcatttc caattcagtc
    10321 acttggaatt cttcaatacc agactcacgg agagcaacga tagccttgtg aaggtcagtt
    10381 ggcgctgtgt aaactgtgat tgtaccttct tgtgcttcta cgtcatccac atccacatcc
    10441 gcttcgagca attgctcaaa gactgcgtct gcatcttcac ctccaaatac aataacacct
    10501 ttgttgtcaa agaggtaaga aacagaacct gaagcgccca tgtttccgcc gtttttacca
    10561 aaggctgcac ggacattggc tgctgtacgg ttgacgttag aagtcaaagt atccacaatt
    10621 agcatagagc catttggccc aaaaccttcg taacgtcctt ctgtaaaggt ttcgtctgtg
    10681 tttcctttgg ctttatcaat cgctttatcg ataatgtgtt ttggcacttg ggcttgttta
    10741 gcacggtcga taacgaattt caaagctgag tttgattctg gatctggatc acctttttta
    10801 gctgctacat agatttctac accaaatttt gcatatacct tagagttagc tccatcttta
    10861 gccgttttct tggctacgat attggcccat ttacgtccca ttaggaatct ccttttttca
    10921 cattttaatc tttattatta taacacaagt ttttttgatt ttcactagag gaaatggatt
    10981 ttattagcaa atcaagctag gatagcactt tacctgctaa gatggtctta cctttctatc
    11041 tttatcaaca gacactcatc cacattcaaa aaacaaacta gaccattatc tgcaaataga
    11101 aagtttcagc caagtttgac aaagtcagct caaattactg tttgaagttt gtagatataa
    11161 gcgacaaaaa caatcatact gcaccttttg ttgacagtct actccagaca tatcatagtt
    11221 caagtaaata ctttgaaatt caacagttct tataggcgct attgtattct aagaaatcaa
    11281 tagaagagtt tctaagcaaa cctctaatac tcaataaaaa tcaaagagca aaccagaaag
    11341 ctagccgcag gttgctcaaa acactgtttt gaggttgcgg atggggctga catggtttga
    11401 agagattttc gaagagtata atttacgtgt tcccaagatg gagaagttag actagtacac
    11461 tggcacttct aaaccattgc tagcaattga tttgttcata tttaatttca ttttttccat
    11521 aaatgggtat tagatataaa cagcaaaata tttccgatac gtgtcgttct tgaatttcca
    11581 atcatctaaa acaagtaaag gataatcaat cccctgtata tcaaggaatt ggctaccctt
    11641 tttacttttt tacacattct gtttgataga ttcattttaa catcacgagc atactccaat
    11701 ggaaatcgct aggcaagaga taaactttca gatatccgca gagagatcat cgcctctttt
    11761 tgtcgcaagc attctcctct cctagtcatt ttctacctta tcttctacct gaggatagag
    11821 agttgttccc caaatagaaa tcgtccgctt acgcactagt ggcaaatcgg ttttttcata
    11881 aaccgtacgc caccattccc aggcaagccc ggtacactct ctaattttga cagagagatt
    11941 acgaacattc ccttttaaag gaatactagt ggtaaagtga gccgttaaat cctgcccatt
    12001 tctgtcccaa gccttaggag tcaagacttc cttaccttga tgatcatagg ataattcatt
    12061 ccaagtaata taatattggg caacataggc accactatga tccagcagta aatctccgtt
    12121 tctgtaagct gtaaccttag tctcaacata gtctgtacta ttttgaaagg tcgcaactac
    12181 attgtcacgt aaaaaagaag ttgtatagga aatcggcaag cctggatgat ctgctgtaaa
    12241 gcgactgcct tcttgaatca agtcctctac catatccacc ttgcctgtta caactcgggc
    12301 acccgaactt gggtcgcccc ctaaaataac cgccttcact tctgtattgt ccaaaatctg
    12361 tttccactct gtctgaggag ctaccttgac tccttttatc aaagcttcaa aagcagcctc
    12421 tacttcatca ctcttactcg tggtttccaa cttgagatag acttggcgcc cataagcaac
    12481 actcgaaata tagaccaaag gacgctctgc agaaattcct ctctgtttta aatcctctac
    12541 cgttacagta tcttgaaaca catctcctgg atttttaaca gcatctacgc tgactgtata
    12601 ataaatctgc ttaaaattaa caatctgaat ctgcttttcg cccgaatgga cagagttaaa
    12661 atcaatatca agagaattcc ctgtcttttc aaagtcagaa ccaaacttga ccttgagttg
    12721 ttccatgctg tgagccgtga ttttttcata ctgcattcta gctgggacat tattgacctg
    12781 accataatct tgatgccact tagccaacaa atcgtttacc gctccgcgaa cacttgaatt
    12841 gctggggtct tccacttgga gaaagctatc gctacttgcc aaaccaggca aatcaatact
    12901 ataagtcatc ggagcacgat cgaccgcaag aagagtggga ttattctcta acaaggtctc
    12961 atccactacg agaagtgctc caggatagag gcgactgtcg ttggtagctg ttacagaaat
    13021 atcacttgta tttgtcgaca agctccgctt ctttctttcg ataacaacaa actcatcggg
    13081 tagctgatta ccctctttga tgaaacgatt ttcaatactt tctccctgat gggtcaagag
    13141 tttcttttta tcgtaattca tagctagtat aaagtcattt actgctttat ttgccatctt
    13201 ctacctccta ataagttcct ggattgagtt gcataaactc agacttgttc agcgaaatca
    13261 gccgtggttg gactaagtaa tccaaaattt cctcgtacaa ttcttctgag acattgcgtc
    13321 gccgtctggc tagataagaa gtcggaatgc ccgtattatc caacataaat accttatcta
    13381 agtcaatcaa ggttggtctt gtaaaaggat tacgagctag atccggctct tctatcataa
    13441 agttcttgac caaacgtctg gtcaagagag ctggtttgaa ggtctgattt ttaaccaact
    13501 ctttgttttt agtcatgctg ttgtcaatac agatatacat atgattcttc acagccaaat
    13561 cgctactaat agtcggaaaa ggcaaataaa gagctacaac atctcctctc ttaatcaagc
    13621 aagagcaccc ccttttctcc taatgtaaca tagacaggat tgaccaagtc ttctgattga
    13681 ctcagaattt ccaaagtttg agtttggcgc gctgtcaatt tagtagcatc ttgtctcttc
    13741 aatacaaaat gcttgtcgcc aataaccttg acaatataat ccttctccaa agctgactgg
    13801 taaatccaca tcagatgttg tctgtcctga gaactcaaga gagaaggatt ttcaagcctc
    13861 ccgatagtct gataaaaatc aaaaacagga gctaactcct gccaatctga ttggctagtt
    13921 gtcaaggcta gaaaaagggc tttgcgagct gatacttctt ggttagcctt gagagttact
    13981 ttcccctcca agttttttag aaatcgggaa actccagaaa gcaaattttt ctctaactgc
    14041 gagaaataaa aacctttcgt tcccagacat aagtctttca tgtcgctttc tctagcaaat
    14101 aagagctcaa acatttgata gtaaaagaaa aatatctggc actgggtcgc gctcatcttt
    14161 tccttatcgg cttctttttt taaccagagc aagggcgaca ggtagctgga ttgagacatt
    14221 tcctctacct cctactcttt tttaactgga gcatctgcac tagctgccac ttcttttgac
    14281 tggatacttt cccactggtt aatctcctct gagataagac cttcgcatgt cttgacaaat
    14341 agggcaaaag ccttggtctt tcctgcatat ttctccgttt ggcattgata gaggaatttt
    14401 tctttctcca ggagttgcgc agttttttgg taagaaatcc aattttcctt tgcattatac
    14461 aaattgataa tcccctcaca cagcaagccg agactggata aggcaaccga aatcaaacgg
    14521 tagcgatcac ctggcatagg aatagcacaa aagacagcta tgaggaaacc tgccacgatt
    14581 tctgttattt ttaatacctt atagcgtcta cgatgttgaa cgcttttctt taaaaaatga
    14641 gctatctgta cgtctaatcg ctctgtcagg tacatttctt ctggcgtcat attcgtaact
    14701 cctttcattt actttgataa ccatagtata acatatttga atatcaaagt atagtaaaaa
    14761 ctggactata acttattaga cttcctgcga aacaaaatat ggtatagtag ttctatgaat
    14821 tatgaagcaa gtaaacaact aactgatgca cgatttaagc gtcttgttag tgttcagcgt
    14881 accacttttg aagagatgtt agctgtatta aaaacagctt atcaaaaaag tcggacaagc
    14941 tggtaaaatc ttggctgaca gtggttatca agggctcatg aagatatatc ctcaagcaca
    15001 aactccacgt aaatccagca aactcaagcc gctaatagct gaagataaag cctataacca
    15061 tgcgctatct aaggagagaa gcaaggttga gaacatcttt gccaaagtag aaatgtttaa
    15121 aatgttttca acaacctatc gaaatcatcg taaacgcttc ggattacgaa tgaatttgat
    15181 tgctggtatt atcaatcatg aactaggatt ttggtttcgc aggaagtcta ttatatatgc
    15241 acagacatat gaaatctttt tgagacagca gttatgatat atttatccat tcacaacatc
    15301 ttctgtacta atactacaat attggtacat tttgattaca caatcgtttc aaaaaatatg
    15361 atggaagcct gagtatttta tagtaattcc cttcctatca actagatcaa ccagttgagt
    15421 gttgaatgtt gaaacaccct agcctcagca aaggactatg atcagcattt cctagccaat
    15481 aggacgctcc aaatcaccta ttctaagtcc atcactagct tggtcagtaa gatacagact
    15541 gcaaggcgag actgacgtgg ttgatgagat tttggaagag tattacaatc atagattcac
    15601 cagtagactt gaccgcagat ttaactatag tagattgaaa ctagaatagt acatctctgc
    15661 ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc aatttgtcct gttctcgttt
    15721 catttcacta tactaaaaaa ccacctgaaa caaatcaagt gactagagga taaaaacaaa
    15781 gactaggcaa aaagttttga aaagcaaaaa acgcataata tcaggtcttg aaaaaccttg
    15841 atactatacg tttgattgtg ggaagattga cttcattttc tcctgaaatt gaagtttttt
    15901 ctagtttcca gatatagacg aattcaatat agccatctcg ctacaattat tttaaccatc
    15961 gagaaaattt ttcagaattt caaaaatttc attttgatcc aatgaaatgt catcattttg
    16021 aagaatagtt gacttcacag gctctaattc tatcacaaag cggtgtatgt ctgcttttac
    16081 cgcactactt gatgttatag ccgataactt ttcatctcct agcaaggaag ctgtcaaacg
    16141 ggtaatgtca ttcaaatgct ttttaatgga cttacttaaa ccttgagcac ctgtagcaga
    16201 gcgttccctc atatccagcc aagctttagc cttaaaaata attaatactc aatgaaaatc
    16261 aaagagcaaa ctaggaagct agctgcaggc tgctcaaaac actgttttga ggttgtagat
    16321 ggaagctgac gtggtttgaa gagattttcg aagagtataa accacaatta ctcaataccg
    16381 aatacccctg aatggtttct ttttcatgca ccaatatatt ataataatct tcatccaata
    16441 ataaggctga taaactagca tcttggtcaa aatgtaaggg aatttctcga ccgtccttct
    16501 ttaatggata ttctggtaag atactaaata gttcaatcat agaaggaaac tcaggattag
    16561 ttgttgtaaa tcgaaaaagc tgcgctttct catctttctg acttccttga tactctccca
    16621 attctaaaaa atgattcaag gtagtataaa attccttatt ttttacttca taaatgatga
    16681 ccatatcata atcttttgtt gtgcgacttt taaatccttg cgaatccaat acgatagagg
    16741 tagcagttcc cccaatcaga acataatagt tctgaaaatc cgcaaacatt tcttgaaaaa
    16801 taactttcgt attagctggc atcatcttct cccagatact gtaatatcat attttctagt
    16861 gcttcactct cttcctctat acgtgggtca tcatcatctt ttaaggtcaa ataaagagaa
    16921 atcggatcta caaattgttt atcatgatta tttttaaaat cattccaaaa ctcagataca
    16981 aaaggacgat atttccatat ctctagcatc tttcatttta aaacatgctg agaaagtggc
    17041 aaggataact gattgaattt tctctgccat atgacatagc tagtattttc atccgtttca
    17101 gctaaaaaag ttgaatgcga caaagcataa gcaccaccat atagaaggtt agaaacagat
    17161 tttatctgct ttatatcgcc atctggcaat aaaaaggcaa tccacgttaa ttgttcgcta
    17221 ggtgttaatt ccttagggat ttcagtatca ttcgcattga gtactagtcc caatggaggg
    17281 aagaagaggt ttcccttaaa gtctacaaac ggaactctag cttgaagtaa ttgctttttt
    17341 tcactgtctg ataacttcga aaacaccaaa acaacatcca tattggcttt ttcacccata
    17401 gtgcgagcct gagtaacaaa tgaactcaaa ctcccccttc tcttttcttt aatcaataaa
    17461 aatgattcct tatgaaaagt catttgagta tactcaaacc tttttacaaa actgattggt
    17521 aaagtcaaag tcagttcctc aatactgaca tcaacataaa aggattgaaa aattgacatt
    17581 atctttttga cattcatgtt ttttc
//
LOCUS       DAVMJI010000040        16496 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.040, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000040 DAVMJI010000000
VERSION     DAVMJI010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.040"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(202..918)
                     /locus_tag="VYR58_001741"
     CDS             complement(202..918)
                     /locus_tag="VYR58_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV3622853.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            1266..3053
                     /locus_tag="VYR58_001742"
     CDS             1266..3053
                     /locus_tag="VYR58_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV3622854.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            3050..3526
                     /locus_tag="VYR58_001743"
     CDS             3050..3526
                     /locus_tag="VYR58_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV3622855.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            3554..4459
                     /locus_tag="VYR58_001744"
     CDS             3554..4459
                     /locus_tag="VYR58_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV3622856.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            4446..5261
                     /locus_tag="VYR58_001745"
     CDS             4446..5261
                     /locus_tag="VYR58_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV3622857.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            5268..5672
                     /locus_tag="VYR58_001746"
     CDS             5268..5672
                     /locus_tag="VYR58_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV3622858.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            5971..7137
                     /locus_tag="VYR58_001747"
     CDS             5971..7137
                     /locus_tag="VYR58_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV3622859.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            7253..8290
                     /locus_tag="VYR58_001748"
     CDS             7253..8290
                     /locus_tag="VYR58_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV3622860.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            8497..9351
                     /locus_tag="VYR58_001749"
     CDS             8497..9351
                     /locus_tag="VYR58_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV3622861.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGIGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     RGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            9501..9737
                     /locus_tag="VYR58_001750"
     CDS             9501..9737
                     /locus_tag="VYR58_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV3622862.1"
                     /translation="MTNSKYITRLKRSEGQLRGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAI"
     gene            complement(9971..10054)
                     /locus_tag="VYR58_001751"
                     /pseudo
     CDS             complement(9971..10054)
                     /locus_tag="VYR58_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
     gene            complement(10088..10180)
                     /locus_tag="VYR58_001752"
                     /pseudo
     CDS             complement(10088..10180)
                     /locus_tag="VYR58_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10216..10512)
                     /locus_tag="VYR58_001753"
     CDS             complement(10216..10512)
                     /locus_tag="VYR58_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV3622863.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNTWPGQVE"
     gene            complement(10502..10663)
                     /locus_tag="VYR58_001754"
     CDS             complement(10502..10663)
                     /locus_tag="VYR58_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV3622864.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            10733..11497
                     /locus_tag="VYR58_001755"
     CDS             10733..11497
                     /locus_tag="VYR58_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV3622865.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            12110..13489
                     /locus_tag="VYR58_001756"
     CDS             12110..13489
                     /locus_tag="VYR58_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV3622866.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            13503..14168
                     /locus_tag="VYR58_001757"
     CDS             13503..14168
                     /locus_tag="VYR58_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV3622867.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            14478..15016
                     /locus_tag="VYR58_001758"
                     /pseudo
     CDS             14478..15016
                     /locus_tag="VYR58_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            15116..15493
                     /locus_tag="VYR58_001759"
     CDS             15116..15493
                     /locus_tag="VYR58_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV3622868.1"
                     /translation="MIRREDQSVNEQVMIKCIDQQLKVNRLLVDQLDLSQVSHPKMRE
                     YLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQENPKVFQAIRKTMLSRLTKH
                     SVLPDRKLSNVVYQITKSVYGFN"
     gene            15609..>16496
                     /gene="pavB"
                     /locus_tag="VYR58_001760"
     CDS             15609..>16496
                     /gene="pavB"
                     /locus_tag="VYR58_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV3622869.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLV"
BASE COUNT         4631 a         3083 c         3727 g         5055 t
ORIGIN      
        1 agtataaaaa aatataaaat ttaaacttaa gatttcagat tggtcgaaaa atacatatat
       61 atatctagta taatttttgg ttctatttct ataaaatatt ccacaaatta tagaatcttc
      121 caaaaatagg taagcgctac ctttttggtg tggtataata agcatagaaa aagcccgagc
      181 gattaggctc aggctttctt cttagtgatc acggtcacat gagatgaatt taatcttgta
      241 gtaatcagat cgtttgtaag tttcactgta ttctaaaact tggccagttg attcgagttt
      301 ggtgatttta gtttgtagga cagtagggaa ttgttcatcg actccgagga ctgaagccgc
      361 atgttctgga gttggaaaga ctatttcgtt gatttcttca aagtgttcat cattcatgtg
      421 aatgtggtag tctaacttga aacgattata gatagaacta tagtattcaa ggtttggata
      481 atttgcgttg atatattgtt ctgggatgta ggatgtatgg tagatataaa cgacaccgtt
      541 tgattcgcgg atacgttcaa tcttgtagta gaattgatcg ccgcgtagac ccaatttttc
      601 caagtaaaca agcttgtttc cgcgttcaat tgaaagaaca gttaccttat catctttagc
      661 attgaagagt tcaatatctg aaaactctac aagcttgtgt ttgcgtgcac gtgaaacgaa
      721 ggttcctttt ccttgttggc ggacaatata gccatctttg gcaaggtcgt ttaaggcgcg
      781 aacaactgtg atagagctga catcgtacat tgaaatgagt tctgcttcag tgtaaaattt
      841 atctccactg ctaaactgcc cagagatgat tttatttttt aattcgtctt ttatgtattg
      901 atatttggga attgccatat ttttacctct attttccttc tccatagaaa attttaccat
      961 aaaagcgaaa aaaatagtag tcttttgaat aaaaaattag aataatagtt tgaaaaatta
     1021 agcgatatag ggattgctca tattttatca atgtattcta tacaaaatta ttttaggtcc
     1081 tatattccga atttaaagag cgtttgaaat gggtctaaaa atgtttgaaa ctaattgaat
     1141 gtgtgtataa tagtaaaaat gcagtaaata tcccgacaat ttctattgac aattcaaaca
     1201 gattggttta taattaatat aacaacaaat gaaatcgcaa actttcgcgg tcggaaggta
     1261 gttttatgac acgatttgag atacgagatg atttctatct cgatggaaaa tcatttaaga
     1321 ttttatctgg tgccattcat tattttaggg ttcctccaga ggattggtat cattcgctct
     1381 ataacttgaa ggctcttggt tttaatacgg tagagactta tgttgcttgg aatttacacg
     1441 agcctcgtga aggtgagttt cattttgaag gtgatctgga tttagagaaa tttctccaaa
     1501 tagcgcagga tttgggtctc tacgcaattg tgcgtccgtc tccatttatc tgtgcggaat
     1561 gggaattcgg tggcttacca gcttggctct tgaccaagaa catgcgaatt cgctcatccg
     1621 acccagcata tatcgaggca gttggtcgct actatgatca gttattgcca agactggtgc
     1681 ctcgtttgtt ggacaatggt ggcaatattc tcatgatgca ggttgaaaat gagtatggtt
     1741 cttacggaga agataaggct tacctgagag cgattcgaca gctaatggaa gagtgtggcg
     1801 taacctgtcc cctctttaca tcagatggtc catggcgagc tactctgaaa gctggaacct
     1861 taattgaaga ggacctcttt gtaacaggaa actttggttc taaggcacct tacaactttt
     1921 cgcagatgca ggaattcttt gatgaacatg gtaagaaatg gccactcatg tgtatggagt
     1981 tctgggatgg ttggttcaat cgctggaaag aaccgattat cacacgggat cctaaggaat
     2041 tggcagatgc agttcgagag gttttggaac aaggctctat caatctttac atgttccacg
     2101 gtggtacaaa ctttggtttc atgaatggtt gctcagctcg aggaactttg gacctgccac
     2161 aagttacgtc ttatgattac gatgcccttc tggatgaaga aggaaatcca actgctaaat
     2221 atcttgcagt caagaagatg atggcaacac atttttcaga gtatccgcag ttggaaccac
     2281 tctacaaaga gagtatggag ttggatgcta ttccactagt tgaaaaagtt tctttgtttg
     2341 aaaccttaga tagcttgtca agtcctgtag aaagtctcta tcctcaaaag atggaggagc
     2401 tgggacaaag ttatggctac ctactttatc gaacagaaac aaactgggat gcagaagaag
     2461 aaagacttcg tatcattgat ggtcgagata gggcccagct gtatgtcgat ggtcagtggg
     2521 ttaaaactca atatcagaca gagattgggg aagatatttt ttatcaaggt aaaaagaaag
     2581 ggctatctag gttagatatc ttgatagaaa atatggggcg tgtcaactat gggcataagt
     2641 tcttagcgga tacgcaacgt aagggaattc ggacaggggt ctgtaaggat ctgcatttct
     2701 tactaaactg gaaacactat ccactcccac tagacaatcc tgagaaaatt gatttttcaa
     2761 aaggatggac tcaaggacaa ccagcctttt acgcttatga ctttacagtc gaagagccaa
     2821 aagatactta cctagacttg tctgagtttg gtaagggggt tgcctttgtc aatgggcaga
     2881 atctaggacg tttttggaac gttggcccaa ctctctcact ttatatccct catagctatc
     2941 tcaaggaagg tgccaaccgc atcattatct ttgaaacaga aggtcaatat aaagaagaga
     3001 ttcatttaac tcgtaaacct acactaaaac atataaaggg ggaaaactta tgacaattgt
     3061 aggatgccgt attgatggac gtttgatcca cggacaagta gccaatcttt gggctggaaa
     3121 actaaatgtt tcacgcatta tggttgtaga cgacgaagtt gtcaacaacg atattgaaaa
     3181 gagtggtttg aaacttgcga caccaccagg tgtgaaattg agtattttgc cagttgagaa
     3241 agctgcagcc aatattcttg ctggcaaata cgatagccaa cgtctcttta tcgtggctcg
     3301 taaaccagac cgcttccttg gtttggtaga agcaggtgta ccacttgaaa cccttaatgt
     3361 tgggaatatg tctcaaacac cagaaactcg ttctattaca cgttctatca acgtagtaga
     3421 caaggatgtg gaagacttcc acaaactggc agaaaaaggt gttaaactta ctgctcagat
     3481 ggttccaaat gatccaattt cagacttttt gagcttatta aaataggaaa aaatttttta
     3541 ggaggtcatt gttatgatac aatggtggca aattttactt ctcactttgt actcagctta
     3601 tcaaatctgt gatgagttga cgatcgtttc atctgcaggt tcccctgtat ttgctggttt
     3661 cattactggt ttaatcatgg gagatgtgac tactggttta cttatcggtg gtaacttgca
     3721 actgttcgtt cttggggttg gtaccttcgg tggtgcttct cgtatcgacg caacttctgg
     3781 tgcggttctt gcgacagcct tctctgtttc acaaggaatt gatgcaccgc ttgcaattac
     3841 tacaatcgct gtaccagtag cagctctctt gacttacttc gacgttcttg gtcgtatgac
     3901 tactaccttc ttcgctcacc gtgtggatgc tgcaatcgaa cgctttgact ataaaggtat
     3961 tgaacgcaac tacttgcttg gtgcgattcc gtgggctcta tctcgtgccc ttccagtctt
     4021 ctttgccctt gcttttggtg gtgcctttgt acaatcagta gtagacttcg ttgaagccta
     4081 caaatgggtt gcagatggct tgacactcgc aggacgtatg cttccaggtc ttggatttgc
     4141 aatcttgctt cgttaccttc cagttaaacg taaccttcac taccttgcta tgggatttgg
     4201 tttgacagct atgttgactg ttctttactc atatgtaaca ggtcttggtg gcgctgttgc
     4261 tggtatcgta ggtactcttc ctgctgaagt tgctgaaaaa attggtttcg tgaacaactt
     4321 caaaggtttg tctatgattg gtatttctat cgtaggtatt ttccttgcag tgcttcactt
     4381 caaaaatagc caaaaagtag ctgtagcagc accttctaca ccatcagaaa gtggggaaat
     4441 cgaagatgac gaattctaat tacaaactta caaaagaaga ttttaatcaa atcaacaaac
     4501 gtagcttgtt tactttccaa ttaggttgga actacgaacg tatgcaagct tctggttacc
     4561 tttacatgat cttgcctcag ttgcgtaaaa tgtatggtga tggaactcct gaattgaaag
     4621 aaatgatgaa agttcatact caattcttca atacttcacc attcttccat accattatcg
     4681 ctggttttga ccttgccatg gaagaaaaag atggtgtagg ttcaaaagac gctgttaacg
     4741 gtatcaagac aggtttgatg ggaccattcg ctcctcttgg ggatacaatc tttggttcac
     4801 ttgtacctgc tatcatgggg tcagtcgcag caactatggc tatcgctggc caaccttggg
     4861 ggatcttcct ttggattgca gttgcagtag cgtatgacat cttccgttgg aaacagttgg
     4921 aatttgctta caaagaaggg gttaacctta tcaacaacat gcaaagtacc ttgacagctt
     4981 tgattgacgc tgcatctgta cttggtgtct tcatgatggg tgctcttgta gcaacagtga
     5041 ttaactttga aatttcttac aagttgccaa tcggtgaaaa gatgattgat ttccaagaca
     5101 tcttgaacca aatcttccca cgtttgcttc cagcaatctt tactgccttt atcttctggt
     5161 tgcttggtaa aaaaggtatg aactctacta aagctatcgg tattattatc gtacttgctt
     5221 tggctctttc tgcccttggt cactttgcac ttggaatgta attccttatg actaaatcat
     5281 taattttggt gagccatggt cgcttctgtg aggagcttag aggtagcaca gaaatgatta
     5341 tgggcccaca agacaacatt tacacagtag ctcttcttcc agaagatggc ccagaagaat
     5401 ttactgctaa atttgaagct gttattgaag gattggatga tttcctagtc tttgcggatc
     5461 ttctcggtgg gacaccttgt aatgtggtga gtcgcttgat catggaaggt cgtgatattg
     5521 acctttacgc agggatgaat cttccaatgg tgattgaatt tatcaatgcg agccttacag
     5581 gcgcagatgc ggactacaag agccgtgctg cagaaagcat tgtgaaagtt aatgacctgt
     5641 tagcgggctt cgatgatgac gaagatgaat aatactcttc gaaaatctct tcaaactacg
     5701 tcaacgtcgc cttgccgtag gtatatgtta ctgacttcgt cagtcttatc cggcaacctc
     5761 aaaacggtgt tttgagctga cttcgtcagt cttatccggc aacctcaaag cagtgctttg
     5821 agcagcctgc ggctagtttc ctacagattt tagttggaac tcgattcaat tcatgtgaca
     5881 acgtgaaaat cgttagagca ttttatatag aatatacatg ggaatggagc ttactcccat
     5941 tcccatattt aatagaaaaa gaggaactca atgctacatt atacaaaaga agacttgctc
     6001 gaattgggtg cagaaatcac tacgcgtgaa atctaccaac agcctgatgt atggagagaa
     6061 gcttttgaat tttatcaagc aaaacgtgaa gaaattgcag cctttctaca agaaatcgct
     6121 gataaacatg actatattaa ggttatcttg acaggtgctg ggacttctgc ttatgtggga
     6181 gataccttgc taccttactt taaggaagtc tatgacgaac gcaaatggaa tttcaatgct
     6241 attgcgacaa cagatatcgt tgccaaacca gcaacctatt tgaaaaaaga tgtggcaact
     6301 gtccttgtgt cttttgctcg tagtgggaac tcgcctgaaa gtgtggcgac tgttgatttg
     6361 gccaaatcct tggtggatga gctttatcaa gtgacgatta cttgtgcagc agatggtaaa
     6421 ttggctcttc aagctcacgg tgatgaccgt aatctcttgc tcttgcaacc agctgtctct
     6481 aatgatgctg gatttgccat gacttctagc tttacgtcta tgatgttgac agctctcttg
     6541 gtctttgatc ctacagaatt tgctgttaag tctgaacgtt ttgaagttgt atctagtctt
     6601 gcccgtaaag ttttagacaa ggtagaagat gtcaaagagc tcgttgattt agactttaac
     6661 cgtgtcatct atctaggcgc tggtcctttc tttggacttg ctcatgaagc tcagctcaag
     6721 attttggaat taactgctgg tcaagttgcg accatgtatg aaagcccagt tggcttccgt
     6781 cacggtccaa aatctcttat caacgacaat acagttgttt tggtctttgg tacaacgaca
     6841 gcctacactc gtaagtacga cttggacttg gttcgtgaag ttgctggtga ccagattgct
     6901 cgtcgtgttg tgcttttgag tgatcaagct tttggtcttg aaaatgtcaa agaagtggtc
     6961 cttggttgtg gcggtgtctt gaatgatatt taccgtgtct tcccttacat cgtttatgcc
     7021 caactctttg ctctattgac ttcactcaag gtagaaaata aaccagatac accgtctcct
     7081 acaggtacag taaaccgtgt agtacaaggt gtcataattc acgaatatca aaagtaagac
     7141 agtgtttatg aattcttgac aagaggattt gtaaattatc agataaacca tagattgtca
     7201 gtacgctttc tatggtttgt ttgcttgaga gaaatagtaa aaggagaaca gaatgaaagc
     7261 atacacagag cgtgtatttg gaaatgttga gggcgaggat gtcttggcct atcgatttga
     7321 gacagacggt ggctaccaac ttgaggttat gacttatggc gcgaccatct tgcgctatgt
     7381 cgcacctgac aaggctggaa attttgccaa tgttatcttg ggatttgatg actttgatag
     7441 ttatgtaggc aatagtccca agcatggagc aagtgtaggt cctgtagcgg gtcgtattgc
     7501 aggtgcgacc tttgagctca atggtaagac ctatgacctt gaggttaata atgctagcaa
     7561 ctgtaatcac agtggttcaa ctggttggga ttccagcctg tttgaagttg aagaagtaag
     7621 cgatcatggc ttgactctct acacagagcg tacagatggg acaggagggt tccctggaaa
     7681 tctcaagatt tggatcagtt atcacttgga agaaactggt gcctatgaaa tcatctacaa
     7741 ggtaacgacc gatcaggata cgctggtcaa tccaaccaac cacagctatt tcaacttgtc
     7801 tggtgatttc acgcagacga ttgaccgtca tgtcttccaa ctaaacacag agggcattta
     7861 ctcaatcgct cctgacggtg ttcctgccaa aactccagaa gccaaccgtg atgtggtcaa
     7921 acacatctac aatggtacct tgttgaagga tatctttgca gaagaagatg agcaaatcca
     7981 gctggcatca ggtttggatc acccatttgc ccttcctgca ggccatgaca atgctggatt
     8041 cctttatgac caaaattcag gtcgcttcct gcttttcaag acagaagctc cttgctttgt
     8101 ggtctacaca gcaaactttg tggatgaaag tgtcatcata ggaggtcagc caatgctaca
     8161 gcacaatggg attgctcttg aagcgcaagc tttaccagat gccattcaca gtgaccttaa
     8221 aggccaagtc attcttaaag ctggtcaaac cttcaccagt aagacacgtt atgaacttgt
     8281 tgtgaaataa aaaagctggt caaaaagtct ttaaaattaa aataacgcat attgtcaggt
     8341 gatgaaaagt ttgataatat gcgttttatt atgaaatgat ttactttata ttatcctgaa
     8401 atggtgttat ttttgagtta tctggcttga ctttcttgat ggaaattata taatagttgt
     8461 aacaataata attacaacga gaaaagagga ccatttatga cctatgaata caagagtcac
     8521 atttatttgg cagagacagt tttaaatgta aaggatttgg ccagtcaaac agccttttat
     8581 cagcaagtta tcggtttaga aatcttatct caaactgaga cagagtccat tctaggcatt
     8641 ggtggaaaag tcttggtaca gctgattcaa gcacaagaga gcggagaagt gagggaacat
     8701 tatggtcttt accatttggc cattctcttg cccacacgca aggctttggc tgatgtcttg
     8761 aaacacctga cagatttaca gattcctctt gtcggcggtg cagaccatgg ttacagtgaa
     8821 gctatttact tggaagattt ggagggaaat ggcattgaac tctatcgaga taagccagtt
     8881 tccacatggg atattcgaga agatggacgc attatcggag tgacggaggc tcttgcggcg
     8941 caggacattt atgagttggg ggaaagagta gagcccttta tcctggcaga aggtacgaga
     9001 atggggcata ttcatctttc cgtcaaggat agtcgaaagt ccagccagtt ttatcaaaag
     9061 gtgttagggc tagagaataa attcagtgtg cctggcgcta gttggattgc ggctggagat
     9121 taccatcatc atttagcagt taacgaatgg agaggaaaag gtctggcttc gcgtaagcaa
     9181 ggcttaccag gtttagccta ctatgtcatc gaagtcgcac ataaaaaaga actgttaacg
     9241 attgcccaac gagcacaaga agttgacgca ccaatcaaat ggatgacatc gagcaaattg
     9301 gaaatcacag actcagatgg catcgtgacc cgtattcgtt tagcaaggta aaattaggaa
     9361 tttttaataa gttataagta ttgctagttt gctttttgaa cggtctttgg taacagaact
     9421 gcgtgagctg gatgggtgag aattttgaca aagaagctga ttagagatat aatgaagaaa
     9481 aatcgagcaa ggaaaaagaa atgacaaatt caaagtatat tactcgtttg aaacgttcag
     9541 agggccagtt gcgtgggatt caaaagatga ttgaaggaga tcgtgactgt gctgatattg
     9601 tgacgcaact gacagcagtg aaatctagtg tagagcgcgt gattgagatg ataattaccg
     9661 aaaatcttac tgaatgtatc aatcagcccc tagatgattc tgaagctcaa aaggaacgcc
     9721 tagagaaggc tatctgatac ttgattaaac ggaaataaat gaatgttttg agacgatatg
     9781 tgcaaaggtc tattaactat tagaatagtt taatgtaagt caaaagaagt tgtaaaaaat
     9841 ctttaaaatt aaaaaacgca tagtatcagg tattgaaatg tactgccccc caaaagttag
     9901 attttttctg tctaactttt ggggggcagt acataaaaac cttgatagta tgcgttttat
     9961 tgtggggaga cttatactct tcgaaaatct cttcaaacca cgtcagtttc accttgccgt
    10021 agatatggtt actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga
    10081 cttcgtcagt tccatccaca accttaaaac agtgttttga gcagcctgcg gctaacttcc
    10141 tagtttgcac tttaattttc attgagtatt acttcatctt ctcatgaaat tgagtttttg
    10201 cccagctcct cttgattatt ctacttgacc gggccaagta ttcataccac cttctacgtt
    10261 ggtaacggtg aggccttggg agctgagaaa ttggcaggta gatgcagagc ggactcctcc
    10321 ttgacaaata acatagtatt catggtcagg tttgagttct ttgtagcctt gctctaaggt
    10381 acttaatgga agatttttgg cacctggtgc atgtcctgct tggaattcat gtgcttcacg
    10441 gacatcgata agttctagat tttcattttg gtattttcca taaaagtcag ccatgctgat
    10501 actagtttcc atattctact ccttctgggt tagccatttt gtatagtgaa taagcgccgt
    10561 caaggttttg gacggtaaat cctgcttgct tgaggatagg ctctgcgata tagctgcgca
    10621 aaccactgtg gcagctgacg atgtaggctt gttttttgtc cagttcatca gcttcctcct
    10681 tgacactttg tcagtttttg atacaatagt acaaaattag aggaggtggg ctatgattca
    10741 gaaacatgcg attcccattt tagagtttga tgataatcct caggcggtta tcatgcccaa
    10801 tcacgagggg ttggatttgc agttgccaaa gaagtgtgtc tatgcttttt taggtgagga
    10861 gattgaccgc tatgcgaggg aagtaggggc gaactgtgtt ggcgaattcg tttctgctac
    10921 caagacctat ccagtctatg tcatcaacta caagggtgag gaggtctgtc tggctcaggc
    10981 tcctgttggc tccgctccag cagcccagtt tatggattgg ttgattggct atggtgtgga
    11041 gcagattatc tctactggga cctgtggtgt cctagctgat atagaggaaa atgcctttct
    11101 agtccctgtt cgcgctttgc gagatgaggg agccagttac cactatgtgg caccttgtcg
    11161 ttatatggaa atgcagccag aggctattgc tgctattgag gaagttttgg aagacagagg
    11221 gattccttat gaagaagtca tgacctggac gacagacggt ttttaccgag aaacggctga
    11281 aaaggtggct tatcgtaagg aagaaggctg tgctgttgtg gagatggagt gttctgctct
    11341 tgcggcagta gctcaattgc gtggggttct ctggggtgaa ttgttgttca cagcagattc
    11401 tctagcggac ttggaccagt acgacagtcg tgactggggc tcggaagctt ttaataaggc
    11461 gctagaactg agtttagcaa gtgttcacca cctttagttg tactggcaaa ggatttgttt
    11521 tatcataaaa tgtctagctc atacttttca aaaatatgtt taaacgaggt caccttcctc
    11581 ttgtcctagg catgttgagg ttgggaaaaa tctttaaaat cagaaaaacg tatcatatca
    11641 ggtgatgaaa actttgatac tatgcgtttt atgttggtaa gatttagagt gagatgaaat
    11701 gatactcttc gaaaatctct tcaaaccagg tcagcttcac cttgccgtag gtatatgtta
    11761 ctgacttcgt cagtcttatc cggcaacctc aaaacggtgt tttgagctga cttcgtcagt
    11821 tctatccaca acctcaaaac agtgttttga gcaacctgtg actagctttc taagcgatgc
    11881 cttggttctc attgcctata atcaaaaaga gaaattttct cctgaaaagc atatagagta
    11941 gctggcgtta aaagctcctg tcttgctttt ttgacctata gtcacatcta tcaagtattg
    12001 ttcttgccta agctatcaat aaaaaggtgg cattttttag gcttggtgtt agtagatttt
    12061 gccttatcct atctaagtca tttcgagctt tttatggtac aatggaaaca tgttattcaa
    12121 attatctaag gaaaaaatag agctaggctt atctcgttta tcgccagccc gtcgtatttt
    12181 tttgagtttt gccttggtca ttttactagg ctctcttctt ttgagcttgc cctttgtcca
    12241 agttgaaagc tcacgagcga cttattttga tcatcttttc actgctgtct ctgcagtctg
    12301 tgtgacaggt ctctcaaccc ttccagtagc tcacacctat aatatatggg gccaaataat
    12361 ctgtttgctc ttgattcaga tcggtggtct agggctcatg acctttattg gggttttcta
    12421 tatccagagc aagcaaaagc ttagtcttcg tagccgtgca actattcagg atagttttag
    12481 ttatggagaa actcgatctt tgagaaagtt tgtctattct atttttctca cgaccttttt
    12541 ggttgagagc ttgggagcta ttttgcttag ttttcgcctt attcctcaac ttggctgggg
    12601 acgtggtctt tttagttcca tttttctagc gatctcagcc ttctgtaatg ccggttttga
    12661 taatttaggg agcaccagtt tatttgcttt tcagaccgat ttactggtca atctggtgat
    12721 tgcaggcttg attattacag gcggccttgg ttttatggtc tggtttgatt tggctggtca
    12781 tgtaggaaga aagaaaaaag gacgtctgca ctttcatacg aagcttgtat tattattgac
    12841 tataggtttg ttgttatttg gaacggcaac tactctcttt cttgagtgga acaatgctgg
    12901 aacgattggc aatctccctg ttgccgataa ggttttagtt agcttttttc aaacagtgac
    12961 gatgcgaaca gctggctttt ctacgataga ttatactcag gctcatcctg tgactctttt
    13021 gatttatatc ttacagatgt ttctaggtgg ggcacctgga ggaacagctg ggggactcaa
    13081 gattacgaca ttttttgtcc tcttggtctt tgcacgaagt gagcttctag gcttgcctca
    13141 tgccaatgtt gcgagacgaa cgatcgcgcc gcgaacggtt caaaaatcct ttagtgtctt
    13201 tattatcttt ttgatgagct tcttgatagg attgattctg ctagggataa cagccaaagg
    13261 caatcctccc tttatccacc tcgtatttga aaccatttca gctcttagta cagttggtgt
    13321 aacggcaaat ctgactcctg accttgggaa attggctctc agtgttatca tgccacttat
    13381 gtttatggga cgaattggtc ccttgacctt gtttgttagc ttggcagatt accatccaga
    13441 aaagaaagat atgattcact atatgaaagc agatattagt attggttaag aaaggaaaga
    13501 gcatgtcaga tcgtacgatt ggaattttgg gcttgggaat ttttgggagc agtgtcctag
    13561 ctgccctagc caagcaggat atgaatatta tcgctattga tgaccacgca gagcgcatca
    13621 atcagtttga gccagttttg gcgcgtggag tgattggtga catcacagat gaagaattat
    13681 tgagatcagc agggattgat acctgcgata ccgttgtagt cgcgacaggt gaaaatctgg
    13741 agtcgagtgt gcttgcggtt atgcactgta agagtttggg ggtaccgact gttattgcta
    13801 aggtcaaaag tcagaccgct aagaaagtgc tagaaaagat tggagctgac tcggttatct
    13861 cgccagagta tgaaatgggg cagtctctag cacagaccat tcttttccat aatagtgttg
    13921 atgtctttca gttggataaa aatgtgtcta tcgtggagat gaaaattcct cagtcttggg
    13981 caggtcaaag tctgagtaaa ttagacctcc gtggcaaata caatctgaat attttgggtt
    14041 tccgagagca ggaaaattcc ccattggatg ttgaatttgg accagatgac ctcttgaaag
    14101 cagataccta tattttggca gtcatcaaca accagtattt ggatacccta gtagcattga
    14161 attcgtaaag agggatgacc cctctttttt gatgcccaag atggcaaata gagacagaag
    14221 ccccttgtct tctagtaaaa gttcttcaaa ggctggactt tatggtaaaa tagaaagaag
    14281 tgacaagaga gagtaatact caatgaaaat caaagatcaa actaggaaac tagctacggg
    14341 ctgctcaaaa cagtgttttg aggttgcaga tagaactgac gaagtcagta acatctatac
    14401 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtataagaa aaaatcagcc
    14461 ccctaaagga gcagattatg aagttattgt ctatcgccat ttctagctat aatgcagcag
    14521 cctatcttca ttactgtgtg gagtcgctag tgattggtgg tgagcaagtt gggattttga
    14581 ttatcaatga cgggtctcag gatcagactc aggaaatcgc tgagtgttta gctagcaagt
    14641 atcctaatat cgttagagcc atctatcagg aaaataaagg ccatggcggt gtggtcaatc
    14701 gcggcttggc agaggcttct gggcgctatt ttaaagtagt tgacagtgat gactggtgga
    14761 tcctcgtgcc tacttgaaaa ttcttgaaac cttgcaggaa cttgagagca agggtcaaga
    14821 gatggatgtc tttgtgacca attttgtcta tgaaaaggaa ggtcagtctt gtaagaagag
    14881 tatgagttac gattcagtct tgcctgttcg gcagattttt ggctgggacc aggtcggaaa
    14941 tttctccaaa ggccagtata tcatgatgca ctcgctgatt tatcggacag atttgttgcg
    15001 tgctagccag ttctaattgc ctgaacatac tttttatgtc gataatctct ttgtctttac
    15061 gccccttcag caggtcaaga ccaggtacta tctgcctgtc gatttctatc gttatttgat
    15121 taggcgtgag gaccagtctg tcaatgagca agtgatgatt aagtgcattg accagcaact
    15181 caaggtcaat cgactcttgg tagaccagct tgatttgtcc caagtgagtc atcctaaaat
    15241 gcgagaatat ctgctgaatc atattgaaat cacgacggtg atttccagta ccctgctcaa
    15301 ccgatctgaa acagcggagc atctggcaaa aaaacgccaa ttgtggacct atattcagca
    15361 ggaaaatcca aaagtctttc aggctattcg taagaccatg ttgagccgtt tgaccaaaca
    15421 ttctgtcttg ccagatcgca aactgtccaa tgtcgtctat caaatcacca aatctgttta
    15481 tggatttaat taatataagt gttttataag agggatttaa gaaaaatttt aactttttct
    15541 tagtcctttt taatttcagg agattatact agagtcatca aataaagaaa gactctaagg
    15601 agaatcctat gaaattcaat ccaaatcaaa gatatactcg ttggtctatt cgccgtctca
    15661 gtgtcggtgt tgcctcagtt gttgtggcta gtggcttctt tgtcctagtt ggtcagccaa
    15721 gttctgtacg tgccgatgtg gtcaatccga ccccaggtca agtcttacct gaagagacat
    15781 cgggaacgaa agagggtgac ttatcagaaa aaccaggaga caccgttctc actcaagcga
    15841 aacctgaggg cgttactgga aatacgaatt cacttccgac acctacagaa agaactgaag
    15901 tgagcgagga aacaaactct tctagtctgg atacactttt tgaaaaagat gaagaagctc
    15961 aaaaaaatcc agagctaaca gatgtcttaa aagaaactgt agatacagct gatgtggatg
    16021 ggacacaagc aagtccagca gaaactactc ctgaacaagt aaaaggtgga gtgaaagaaa
    16081 atacaaaaga cagcatcgat gttcctgctg cttatcttga aaaagctgaa gggaaaggtc
    16141 ctttcactgc cggtgtaaac caagtaattc cttatgaact attcgctggt gatggtatgt
    16201 taactcgtct attactaaaa gcttcggata atgctccttg gtctgacaat ggtactgcta
    16261 aaaatcctgc tttacctcct cttgaaggat taacaaaagg gaaatacttc tatgaagtag
    16321 acttaaatgg caatactgtt ggtaaacaag gtcaagcttt aattgatcaa cttcgcgcta
    16381 atggtactca aacttataaa gctactgtta aagtttacgg aaataaagac ggtaaagctg
    16441 acttgactaa tctagttgct actaaaaatg tagacatcaa catcaatgga ttagtt
//
LOCUS       DAVMJI010000041        16289 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.041, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000041 DAVMJI010000000
VERSION     DAVMJI010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16289
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.041"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(181..1278)
                     /locus_tag="VYR58_001761"
     CDS             complement(181..1278)
                     /locus_tag="VYR58_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV3622870.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRTQMALENGADLVVELPFLVSVQAADFFGQGAMDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLSYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
     gene            complement(1288..2034)
                     /locus_tag="VYR58_001762"
     CDS             complement(1288..2034)
                     /locus_tag="VYR58_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV3622871.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(2137..2490)
                     /gene="rsfS"
                     /locus_tag="VYR58_001763"
     CDS             complement(2137..2490)
                     /gene="rsfS"
                     /locus_tag="VYR58_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV3622872.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(2503..3003)
                     /locus_tag="VYR58_001764"
     CDS             complement(2503..3003)
                     /locus_tag="VYR58_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV3622873.1"
                     /translation="MKMAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(3004..3597)
                     /gene="yqeK"
                     /locus_tag="VYR58_001765"
     CDS             complement(3004..3597)
                     /gene="yqeK"
                     /locus_tag="VYR58_001765"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV3622874.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVVYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(3597..4226)
                     /locus_tag="VYR58_001766"
     CDS             complement(3597..4226)
                     /locus_tag="VYR58_001766"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV3622875.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(4278..4589)
                     /gene="yhbY"
                     /locus_tag="VYR58_001767"
     CDS             complement(4278..4589)
                     /gene="yhbY"
                     /locus_tag="VYR58_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV3622876.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(4804..5910)
                     /gene="yqeH"
                     /locus_tag="VYR58_001768"
     CDS             complement(4804..5910)
                     /gene="yqeH"
                     /locus_tag="VYR58_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV3622877.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(5913..6503)
                     /locus_tag="VYR58_001769"
     CDS             complement(5913..6503)
                     /locus_tag="VYR58_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV3622878.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(6455..7363)
                     /locus_tag="VYR58_001770"
     CDS             complement(6455..7363)
                     /locus_tag="VYR58_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV3622879.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(7420..7980)
                     /locus_tag="VYR58_001771"
     CDS             complement(7420..7980)
                     /locus_tag="VYR58_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV3622880.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            8119..9327
                     /gene="sstT"
                     /locus_tag="VYR58_001772"
                     /pseudo
     CDS             8119..9327
                     /gene="sstT"
                     /locus_tag="VYR58_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            9395..10348
                     /locus_tag="VYR58_001773"
     CDS             9395..10348
                     /locus_tag="VYR58_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV3622881.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            10492..10872
                     /locus_tag="VYR58_001774"
     CDS             10492..10872
                     /locus_tag="VYR58_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV3622882.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            10971..11192
                     /locus_tag="VYR58_001775"
     CDS             10971..11192
                     /locus_tag="VYR58_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV3622883.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            11209..11523
                     /gene="trxA"
                     /locus_tag="VYR58_001776"
     CDS             11209..11523
                     /gene="trxA"
                     /locus_tag="VYR58_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV3622884.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            11828..12361
                     /gene="queF"
                     /locus_tag="VYR58_001777"
     CDS             11828..12361
                     /gene="queF"
                     /locus_tag="VYR58_001777"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV3622885.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQINREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            12423..12590
                     /locus_tag="VYR58_001778"
     CDS             12423..12590
                     /locus_tag="VYR58_001778"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622886.1"
                     /translation="MFEVVDRTDEVSLKHCFEVADRTDEVSNHTYGKVKLTWFEEIFE
                     EYHTKKPCSSR"
     gene            complement(12615..13283)
                     /locus_tag="VYR58_001779"
     CDS             complement(12615..13283)
                     /locus_tag="VYR58_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV3622887.1"
                     /translation="MKKFVAELIGTFMLVFIGTGAVVFGNGFDGLGHLGIAFAFGLAI
                     VVAAFSIGTVSGAHLNPAVSIAMFVNKRLSSKDLVNYILGQVVGAFIASGAVFLLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLIIGLS
                     LMAMILVGLNITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(13389..14179)
                     /locus_tag="VYR58_001780"
                     /pseudo
     CDS             complement(13389..14179)
                     /locus_tag="VYR58_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
     gene            complement(14604..15368)
                     /locus_tag="VYR58_001781"
     CDS             complement(14604..15368)
                     /locus_tag="VYR58_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3622888.1"
                     /translation="MFKLSFQSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TSDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            complement(15361..16131)
                     /locus_tag="VYR58_001782"
     CDS             complement(15361..16131)
                     /locus_tag="VYR58_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622889.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKIVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
BASE COUNT         4791 a         3655 c         3078 g         4765 t
ORIGIN      
        1 cattatacca caaaataaca agcataaagc ggattcaaag ataaagatta aggttcatat
       61 actaattttc tttattgact ttttgtcttc tgtattaggg agtttatcat tttccaaaaa
      121 ctttatcttc aatttgttat ctaaaatttc tacaataaaa aagcctacct ttcagtagac
      181 ttagtttgtt tctattctaa tcggcactct tccaaaattt tgctctgcta tacttggatt
      241 tcctagttgg taaatctggt ctgctttttg ggtcatagca tcccaaggtt ctttgccaat
      301 tcggctgact agactgacct gacctttcaa agacttgaga tgttgcctgc ctttttcagt
      361 aaatccaagg acatgaatgg cttctggcaa gacattttct ctagcctgca ccaagatata
      421 ggacaagagg cgtctaacac gcgccttggt gtaacgtttg gtagtcacta actcgaccaa
      481 ttcttccaca gactgggctg ttttaatagc ttctttaatg cgcacagcca tttcttgatt
      541 gacctgatag atggtggtta ggtcgggatt tgacaagatt tgatagcgga gcaagggaaa
      601 atagtcttcc cagatcacct tactggcctg ctcaaatagg gcaacagaag gcataaagcg
      661 ttctaagaaa tcttggtcct tctgatgttg acggagggct gtcgccgagg caaagtccac
      721 atctttattc acagaatggt aacctgcccc ctgacgctga atcggatgca gcttgatatt
      781 tcgtcctgca accgccttgg cataggccag agcaagaaca tgattggggg tattacctga
      841 aaaatcaaga ccagcaaatt ccttccacat agcttgggtt ttctggggat aggaaaggga
      901 atcaggcaga ttttccacaa atttctccat ctcagcacct ttctctgtgt ataagtcagc
      961 aattttctga taatctcgaa cttcctctgt cccaaaaact agactatcaa tgcccaagcg
     1021 atccaagata tccatagctc cttgaccaaa gaaatcagct gcctgaacac tgactaaaaa
     1081 gggcaattcc actaccaagt ctgcgccatt ttccagcgcc atctgggtcc ttgtccactt
     1141 atccacaata gcaggctctc cacgctgcat gaaattccct gacatggcaa caattttcag
     1201 tccctctgcc tgatccagca ggtatttatg gccattatga aaaggattga actccgcgat
     1261 aatacctgtt atggtcatgc taatctccta cttctgcgcc acaaaaaacc aacgggtgct
     1321 agtttctgtt ggctccttat cctcaaagtc tgcatagagt ttgaaggact tgaatccagc
     1381 ctgttccagc aagatctcat aggtcaagat ctcataggtc ctctcctcat gtacttcatc
     1441 gtggcgacta aaggaaccat cagcctcctt gataaagaaa gtcagctcat ggacgatgga
     1501 gtgaggaact tcgtcctcat atgtatccca aagcatggca aaatcttccg cattttcatg
     1561 gtaggaatag ccagggaata cttcatctgt ctggtaggtc gagtgcacgt caaagatgaa
     1621 aactccctct tcattcagcg cattgtacac gtccttaaag acgtccccta cttccacctc
     1681 atcctgcata tagcagatag agtccgaata acacgtgaca aaatcgtatt tccctgcctt
     1741 ggacaaattc agcatattac cttctataaa agcaatcttt tgcttggctg aagttgctct
     1801 cttctccgca atcttcaaca tatccgcact caagtcaagt ccagtcacat caaaaccagc
     1861 ctgagagaag cgcactgatt gaattcctgt cccacaagcc aattccaaga gtttctttct
     1921 ctccttggtc ttaggcaaat gacgcagaga aaaattcgtc catttgtcgt ataaactatc
     1981 gtccatgacc gcatcataga ccgccgcaaa ggtttcataa gtcgccataa tcatgatact
     2041 aagagctcca tggtaaacac cactagccct ttacctttct atcaattttt ctaaaataag
     2101 caaagaaacc cagttgacta caactgagtt catcttctaa gcaagagctt ctgaaatatc
     2161 tactgaattc gcctcatgcc atagcttctc tagattataa tgggcacgca tttcttctga
     2221 aaagatatgc acgacaacag caccgaggtc cagtaagacc cagcctccag ctgcatcgcc
     2281 ttcgacatgg ctacctttaa agcctgcttg agctactttt tcacggatat tagctgcgat
     2341 agcgtccaac tgacggctat tcattgagct agtgatgaca aagtagtccg tcacactagt
     2401 caaatcttgt acatcaagtg cgaggatatc ctccgcacgt ttctcatcag ccgctttcac
     2461 gactagttct agtaattctt tttcgttcat ttaatcctct ttttagaaaa tatgtttgta
     2521 atctagaaca tctgcaaagc gctcctccca aatgtcctca taaaattcat taatcgtttc
     2581 tgctggaatg tcatccccat caaaggttgt gacagcacct tctggaacaa taagctgata
     2641 gccatattca aaggcaacct tgacagaggt atccacacaa tattctgtct gcataccaca
     2701 taaaactaat ttttcaatcc cctgcttatc caagtattct tttaagccag tttctttgaa
     2761 aatactgtta tatttcttct gaaagacctt ttcagcaggt tttcgattta aaagcgcaga
     2821 taactgccaa tcttctgatg tttgagcttc agagttctca atatgttgaa catagataat
     2881 ttcaatattc ttgcttctag cctggttttg taaataagaa attttttcca atagactttt
     2941 tgtctggaac ccagtttcta ctaaaacatt ctgaacatca atgattataa aagccatctt
     3001 catttagttc tctttcaaat agtgcacaaa ggcgttatag gtttcaaggg tttggggata
     3061 gatggggaat ccctgatgag ctagatactc cacggtacga gctgtttcgt aggccaccgc
     3121 cttattgagc gatagacttg caatctcacg cgccacatct actccaggaa aggctcgatt
     3181 gtgctcgata tagtctgcta catagacaac cttatctagg tctgtcatct gaccagcacc
     3241 gactgtatgg acttcaatgg ctcgcaggat ttctgaatca tgcaaatcca aatcttcctg
     3301 aattttgtaa attccgacca taccatgcca gacattatta ccccagtttt tgaggtcagg
     3361 gtctagctgg taacggtcaa tcaaagctag aaattcctga tctgacaact ttttagcata
     3421 gtcatgaaga agacctgcta gacttgcttt ctcaacatct acaccaaagc gctgagctaa
     3481 ttccatagcg gcacgctcca cacctagaca atgggttaga cgtttctcag gtagaagctc
     3541 tgccattttt tccaacaagg cctcacggga gcagttgata tagtcttgat aggacatcag
     3601 tagagcccct ccttctcgat gtagtctagc actggctgag gtaggagaaa gttgggtttc
     3661 cgaccttggg caatgaagtc ccgcaccatg ctggacgaga tatccatgag cggtacgtcc
     3721 acccagataa ctggatagga agtccctgcc ttgtagcgtg gacgctgaac ccccacaaac
     3781 tgaaccatgt caaccagttc atcaattcgg taccacttag gcagatagtc aaccatgtcg
     3841 gcaccgatga taaagtaata atccgtatct ggattcttct ctgtcaaaat cttcatggtg
     3901 tcgtaggtgt aggaaatacc cttgcgctcc aactcaatgg tttcaatgac taggccgtca
     3961 attccctcaa ttgccaactc aagcatcttg agacgatggt gttcagggat ggtttccttt
     4021 ttatcaacgt gaggaggttg gtattcaggc atgagaagaa cttgatccag tcccaactgt
     4081 tgccgtactt gatccgcaac aatgagatgg gcattgtgaa cagggttaaa attcccccct
     4141 aaaatcccaa cttgtttgcg ttttttctcc ttgatttctg gctccaactc taccttggta
     4201 aagggagtca atagttcgat tgtcataggc tagtcccctt tatttctcta taaaaacagt
     4261 tatttggagt ttcggtctta gatttctttg actttcttag aaatcttgcg attttctttc
     4321 ttgctagatt gtttaaacaa aatcaagatg cgtcctattt tttggactgt atccacaccg
     4381 atttcttctt ccaaaatttc agctacttcg tggatgtttt catctgtgtt ttgtaagaga
     4441 gtaaccttga ttaattcacg cgcatcaaga gcttgacgga cgctggtttt gatttggtcg
     4501 ttgagtccat ttttcccgat ttggatgata ggtttgaggg tgtgtgcctg gctgttgagg
     4561 aaggcacgtt gttttgatgt taatgacata atttctttaa aagagtttct ttttatactt
     4621 ttctgaagtg gtgacggacg tcagcaaagt ccttcggact ttcatgacta aaatttgagc
     4681 ctaaggtctc aaattttccg cagttggtac aatcacttgt accaacttac accacagcga
     4741 aaagtattct ctatggggct cgccttgctc gcccaaattc agacaaccct ttcctttctg
     4801 tgcttaaata attgcttttc gtgtgacgac ggcgacgcct tctggtgccc agacggcgac
     4861 ttttgctatg cctgttacac gaatccaacc taggcctgag atgactaggt ctgtcttatc
     4921 tttaatggta aagacatgct ggactagcct tgggaaatct tctttttcct tgctatttgg
     4981 tggtgtcaga agagttccca ggtgcttatc gtagaaagca ctagctcctt caagcttgct
     5041 acgatggagt ttgagttcat tatcaaagaa agcagtaaat ccttgctttt ctcctgctat
     5101 aaagtcaaag cgtcccaaac cacctaaaaa tagggtttgc tcaggattaa gctgataggt
     5161 cttaggcttg atttcctttt taggactgac atacttgagg tttttggccg tcaagtagtg
     5221 agccatctgg tggcggtgga taattcccgg cgtatcgtaa atataagatc cgtcgtcaag
     5281 cggaatctct attttgtcca aggttgtccc tgggaagcgt gaagtagtga tgacattctg
     5341 atcacccgtg atttcttgga taatagcatt gattagagtt gattttccaa cgttggtcac
     5401 accgaccaca tagacatcgc ggcccttacg gtagtgttca atcttgtcaa tgacttcctt
     5461 aatggcatgt ttattttgtg ctgaagttag gaccacatcg actggacgaa gaccttcttc
     5521 atgggcacgt ttcatgagcc actggctaat cttaccagac ttaactgact tagggaggat
     5581 atctttttta tttcctacca agaggacatc attgcccgag acgaaacgtg gtaaacctgg
     5641 gatgacagag ccattaaaat caaagatatc aatgacattg accactaagg catcactgtc
     5701 tcccacctcg tgcaagagct tgaggaaatc atcgttcgtc aactggacat ctgtgatttc
     5761 attgtagtgg cggagacgga aacagcgttg gcaatagact tcgccagtct ccaaaccttt
     5821 ttcaagtgcc gactgggggg taaaaccaag accagcttta tctgtcgtct gaatggttgc
     5881 tccacaacca atacagagaa tttcttccat agttaaattc cttttttata tgtaatcggt
     5941 ccgtactttt cagtgatttt tctcataaca cgacgctcac gagttcggtt aatctgcgtt
     6001 ttgattgagt catgttggac caagggtttg actaaaattg accgaatccc tgcacggtgg
     6061 gctgctcgta tatctgtcat gagctggtcg ccaaccatga ccacttcctt tttgtcatag
     6121 tggaattcct tcatggcacg gtcaatacca aatgtgaagg gcttcaaggc ccagtaaacg
     6181 taatcaatcc caaatttctc aactgctcgt tgaacgcgtt ttttggtgtt atttgacact
     6241 acgataatgc caatacccgc gtcccgaagg tcatgtagcc attgcttcat ctctggcgtt
     6301 ccatcagggt tgttccaagc aatgagggta ttatccaaat cgaccaaaac agccttgatt
     6361 ccctgcgcct gcaggcttgg gactgtcaga tcatagactg cttccacagc aaaatctggt
     6421 atataatttt caatcgccat tctggctcct tttcttaact ttttttcgca attttcctta
     6481 gtaacaagga taaaacaatc cacaaacctg cactagccaa actgatatag agccaagcat
     6541 ggggctcatc tgttaaaggt aagggaacat tcattccgaa aaagcctgtc acgactgcca
     6601 aaacagctag caagactgaa atgatagtca aggttgtcaa attgtcattc agattattgt
     6661 ttagaatatt gttgtaagag gctgaaagct gctgtaaaat ctgagagatt aggtctgtca
     6721 tggataccag ctgatgagcc tcaatcatag catcatcaaa ctgttctctc tcaatctcat
     6781 caaaactacg atacaaggca tgaccttgaa tatgctctaa caaaatccga ttttgtttgg
     6841 cagctgccgt cagataaacc ataccagtct ccaaatcaga cagggcaaag aggtttttct
     6901 tggtagttcg ctggcgcaag aggtcattga cctcatccct actcttgtcc atctgctcaa
     6961 tgacaggata gtaggcattg ctgatgattt ccagactggc aaagagaaac ttataaatcg
     7021 aaagcgtgtc atggctctcc agataacgag tcatctgttc aatgacatag gcgttcttgg
     7081 tattactaat ggtaatcagg cgacgatgct cgacgataaa ggtcatggga aaagtctcat
     7141 agtaggcctt gtcctttttt acgtctagga cattatagat aaaggtaacc gtcccacttt
     7201 cacggtggta gtccatgtgg gcgcgctcgt ttctatccag tgcgtattca atggtttcct
     7261 tgtccaaacc gtaaatttca gaaaggtctt ctagtttatt caactttcct aggtctaggt
     7321 ctatccaggt acaaccattg cccaactgct tttctaaaac catcttttct ccttattaaa
     7381 ctccctctat tgtaccacaa attacttaaa ataacaggtc tagtctgtgc gtgagaaatt
     7441 gctaacaact gtgatatttc ggttagggac aaagtgaagg gcttgctcct cgctacgcag
     7501 ctgtgtcgta cgaattccca cactgacaac cttacccgat acagtaatcg gtccatttgt
     7561 cagaacgacc tcatctccca catccagttg acgttcaaag aggatgaaaa agccattgat
     7621 gacatcagac agaaagcctt gggctcccat accaatcgct accccagcaa taccagctcc
     7681 agccagcaaa ctagaaactg gcaaacctaa aatagacaaa atgcagtaga gtaaaaagaa
     7741 atatagcgta taattaaaca cattttctag taaacgtgag atggtttttt ggcgtccgac
     7801 atcatgacga gacattttta gagaaggttt gacaattctc tgcaccatgg tatgaagcat
     7861 ttttttagca atataaaata caatcaaaag cagtaaaaga gaaatgacct tggttagaat
     7921 attctcgata atggttgtca catctagctt ttcaatataa gcctgaataa atttttgcat
     7981 ataaaactcc tttatttcat tataccatat tttcatcagt ctcattctcc ataaatattc
     8041 aaaaaataga cagaaaattc ttgattttgt ctatcattta tactataatc ataatcacta
     8101 cacaaaaagg agattattat gaaaagaatc attcatgctt ggaataaggc aagccttgtc
     8161 aagcgtatct tgattggtat gctttgtggg gaatcctagg actgaccctt cctaatctct
     8221 cagggattgg gctactcggg gatttattcg ttggaggtct aaaagctgtt gctcctatcc
     8281 tagtctttgc cctcgttgcc aatgcccttt cccaacatca aaagggacaa gatagcaata
     8341 tgaaaactgt tgttttcttg tatatcctat gatagggact ttcgccgctg ctcttgtagc
     8401 tgtactagca agtttcatcg tccctattga aattacccta aatagtgcca atactgaaat
     8461 tgcaccacca gatggggttg ggcaggttct cagcaacctc ttgctcaaac tggttgacag
     8521 cccagtcaac gccctgttta ctgctaacta tattggaatc ttatcttggg cagtcatttt
     8581 tggaatcgct atgagagaag ccagtaaaaa tagtaaagaa ttgctaaaaa ctatcgctga
     8641 cgtgacttct aaaattgtcg aatggatcat caatctggct ccatttggaa gccttggtct
     8701 tgtttttaaa accatttctg acaagggagt cggaagcctt gccaactacg gtattttatt
     8761 ggttctatta gtaacgacta tgctttttgt tgcccttgtg gtcacccttt gattgccttc
     8821 ttctttatga gacgtaatcc ttaccctcta gtttggaact gcctccgtgt cagcggtgtg
     8881 acagcctttt tcactcgtag ttctgcggct aacattcctg tcaacatgaa actctgccat
     8941 gaccttggac tcaacccaga tacctattct gtttctatcc cactcggttc tactatcaat
     9001 atggctggag tagcgattac cattaacgtt ttgacccttg ctgcagttaa cactcttgga
     9061 attcctgttg actttgccac agcctttgtc ctcagtgtgg tagcagctat ctcagcctgt
     9121 ggtgcttcag gtattgccgg aggttccctc cttcttatcc cagttgcttg tagccttttc
     9181 ggtatttcta acgatattgc catacaagtt gttggggttg gttttgtgat tggtgtcatc
     9241 caagactcat gtgaaacagc ccttaactct tctacagatg tcctctttac cgccgttgcc
     9301 gaatacgcag caacccgtaa aaaataactc atcaaggcaa gcctgctcat gtcttgtctt
     9361 ttacgctttt attctaactt attaggaaat tcttatgtct attagccaac gtacgaccaa
     9421 gctcatctta gctacctgtc ttgcctgcct gcttgcttat tttctcaatc tttcatcagc
     9481 agtttcggct ggaattatcg ctctcttgag cctatctgat acgcgtagaa gtactttaaa
     9541 actggctcgc aatcgtcttt tttctatgct tctagctctg gctatcggtg ttctagcttt
     9601 tcacttgagc ggatttcata tctggagtct cggcctctat ctggccttct acgttccttt
     9661 agcctacaag atgggctggg aaattggcat cacaccaagc actgttttgg ttagccatct
     9721 cttggttcaa gagtcaacct ctccagacct tctagtcaat gaattccttc tctttgctat
     9781 tggtacagga tttgccttgc ttgttaatct ctatatgcct tcacgagaag aggaaatcca
     9841 gcactaccac acgctggtgg aagaaaagtt aaaagatatc ctccagcgct tcaaatacta
     9901 tttatccaga ggagacggac gcaaccgagc acagctggta gcagaattag acacgctttt
     9961 gaaagaagcc ctcagactgg tctatttgga tcactctgac cacctctttc accagaccga
    10021 ctaccatatc cactactttg agatgagaca acgacaaagt cgtatcctga gaaacatggc
    10081 ccaacagatt aacacttgtc accttgccgc cagtgaaagc ctgatcttag cgcaactctt
    10141 ttcaaaaatt gcaggtcaac tgagccagac caatcctgct tctgatttgc tagatgaaat
    10201 tgaacgttat ctggaagtct tccggaaccg cagtctgccc aagacaagag aagagtttga
    10261 aacccgcgcc acccttcttc aactcctacg tgaagccaaa accttcatcc aagtaaaagt
    10321 tgatttttac caaaaatatg gacagtaaaa aataaaacca ctaaaaaaca gagcttgcca
    10381 gcattcttga aaagtagtat aattattgca tgcgcaatca tcttgtgacg cagagactgc
    10441 ccgttaatgg actttcttct attttatgac tctaaaaaga aaggagacac tatgacctat
    10501 ttggaaaaat ggtttgactt caatcggcgt cagaaagaaa ttgaaagtct cttggaagag
    10561 accattgccc aacagagcga gcaaagtctg accttgaaag agttctacct gctctactat
    10621 ctggacttgg ctgaagaaaa atctctacgc cagattgacc tgccagataa gcttcatctg
    10681 agcccgagcg cagtttctag gatggtggct cgcttggaag ctaaaaattg cggtctactc
    10741 agtcgcatgt gttgccatca agatagacgc tctagtttta tctgcctgac aaatgatggg
    10801 caaaagacac tggcctcgct acaaaagact gtcgaagaaa gcttggaagc aggtttggat
    10861 ttcttgattt aagatgattt taaaaaaagt tgcgtgcgca atcatttttc ttgacattct
    10921 cttttataag gagtaaaata aagttagcat taaacaaagg agttttaaat atgattgaaa
    10981 ttacctatat agatgccagc aagaacgaaa gaactgtgac tttcgagtct tatgaagact
    11041 ttgaacgttc gcaacaagct tgccttatcg gcgtcgcaga ctactaccct gtccaaaaat
    11101 taacttacaa gggccataat ttggactacc atgggactta tggagatatc ttcttctatc
    11161 tcatgaaaca agatttaagc caatataact aaaaaaagga gaaatacaat ggcaaaagca
    11221 attacagatg caacattcga acaagaaaca aaagacggtt tggtcttagt agacttctgg
    11281 gcaacttggt gtggtccatg tcgtatgcaa ggtccaatct tggacaaatt gtctgaagaa
    11341 ctttcagaag atgtcttgaa aatcgttaaa atggacgttg atgaaaatcc aaacacagct
    11401 cgtgcttttg gaatcatgtc tattccaact cttctcttca aaaaagacgg ccaagttgtc
    11461 aaacaggttg caggtgttca cacagcagaa caaatcaagg ccatcattgc tgaattgagc
    11521 taatcaaacg agagaccaag tactttcttt ggtctctttt ttcttgccct ttgccatttt
    11581 tcaaaaaata tgctagacta tagcagattg aaactagaat agtacacctc tacttctaaa
    11641 acattgttag aaatcgattt gactgtcctg atcgatttgt cctgttctta tttcatttta
    11701 ctatataagt agaatattac gatgtttggg atatgccatc gctaaaaaaa ctcgatttgg
    11761 tattttttag ctccctaatg ggagcttttt gcatgctctg aacatttccc attttggaag
    11821 gagtactatg aaacgtcaat cagccttggt cgtctttagt ggtggtcaag attcaacaac
    11881 ctgccttttc tgggccatgc aacactatga aacagtcgaa gctgtcacct ttgcctacgg
    11941 ccaacgtcat cacctcgaaa ttcaaattaa tagagaaatc gctaaggaac agggcattcg
    12001 tcaccatatc ctcgatatgt ctctgctggg acaaatcact gctcagccag actttgcgac
    12061 gattcatatt tcctacattc ctgacaagct ctgtgtcgag tcaaaatccc tcaaactata
    12121 tctatttagc taccgaaacc acggagattt ccacgaaaac tgtatcaaca ccatcgggaa
    12181 agacttggtc aacttgctag accctcgcta tttagaagtc tgggggaaat tcactccgcg
    12241 cggtggcatt tcaatcgacc cctactacaa ctacggtaag caaggaacta agtatgaggg
    12301 cttggcagaa caacgcctct tccaacacga cctttatcca gagaaaattg acaaccgcta
    12361 aagtcatact caatgaaaat caaagagcaa actaggaagt tagccgcagg ttactcaaag
    12421 cagtgtttga ggttgtagat agaactgacg aagtcagctt aaaacactgt tttgaggttg
    12481 cagatagaac tgacgaagtc agtaaccata cctacggcaa ggtgaagctg acgtggtttg
    12541 aagagatttt cgaagagtat catacgaaaa agccctgttc ctcaagatga ggagcaaggc
    12601 tttttgagtt tcaattattc ttctgttcca aggaaatttt ttgcaacaag ggctgcaaga
    12661 actccaccag cgattggtgc aaggatgaaa atccaaactt gttgaagggc tgcgccgcct
    12721 accaagacag ctggtgccaa gctacgagct gggtttactg aaagtccagt aatgttcaat
    12781 ccgacaagga tcatcgccat caaggacaaa ccgattatca aaccagcaat cgcgccattt
    12841 cctttacttt ctgaagtcac agtcatgata accaaaacaa acaagaaagt tgcgatgact
    12901 tcaaacaaga aaccaccaaa gacagtgaca ccgtttgcca aagcattttc accaagacta
    12961 gcagttgaca tacctgaatt tgccaagagc aagaagacag cgccagaagc aataaaagct
    13021 ccgacaactt gtccaaggat gtagtttaca aggtcttttg atgacaaacg cttgttaaca
    13081 aacatagcaa tcgaaacagc tgggttcaag tgagcacctg aaacagttcc aattgagaaa
    13141 gctgcgacta cgattgccaa accaaaggca aaagcaattc caaggtgacc aaggccatca
    13201 aaaccatttc caaaaacaac agctcctgtt ccgatgaaca caagcatgaa cgtaccgatt
    13261 aactcagcaa caaatttttt cattttcttt ctcctttttt caaaaactag atactagtct
    13321 atcaaaagag ggaaagggtt tcaagaaaat tgcttggaaa gttttttgaa aatctgactc
    13381 gctttttctt agtattgaaa agactggata gcttctttca agtcatcttg taaactattt
    13441 ctctggtcaa gttgaacata gacttccaac agacaggatc tgaagttgga aaatttataa
    13501 aaatcttctc tttcttctat cggaaagtca acagctttta tccaagaagc tacttgctct
    13561 tgcgctaact tcccttgtaa aataggttca tagatcactc ttgctaaacg ccaatcctca
    13621 tcatctgtaa agcgaatcga aactctttta aatagttggc caagtatatc aaatacttca
    13681 tgaactctgt ttttaggaaa gttgggatga caaaccacct ctgtcagtaa atcggctcca
    13741 tgtgcaaaag catgaaccca accatactga cttgaaaaac ccgttgtatc cttttctttt
    13801 gaaagataat acaaaccttg atttaaaagg acattacgaa ttcctgcatt taattcctga
    13861 taaaaatcga ttgctggttg gcatctgcag acaagagatt tgcataaata agcgccctaa
    13921 aagaacgttc aagggttgac aggcctacct tatcaatatc tttatctaac cctccatcag
    13981 atgaaatccc ttcagcaatg aaatgaaatt gttcctgtgt aaatagctct tcctgaatcc
    14041 ctctagcaaa gcttgtaaaa acaaggtcat cacgaatttc tggagaagga tctcccaaat
    14101 gatcaagtag ccactggatt tcttcctggt tataacttgg tttttcttct gctatttttc
    14161 taagtaactt ttgatacatg gtcaatacct ctacatttct agcaactgtt caaaaagctg
    14221 tccttaaatg actttagcaa tttgtaaaat taagttaaag agaaaaagac atttatattc
    14281 agagaaacag cacatttctg aaaggataca taaatgattt attccatatt accacaaatg
    14341 aacttgtaat gatagaactt tatcacaaaa atcacatttc tgtctcaaaa attgcgaaaa
    14401 actagttata ataaagtgaa ataaaaacta tacaaattga ttagggaatt taaaacaatt
    14461 tctaacaata ttttaaaaac tgaaccgtac tatttcaact tccataaatt acaatattga
    14521 taggcacagt tcccatacct gtccaaattc gaataacgtt tagtataaat tagaatatga
    14581 ctacaacatc acaaataatt agactatcta taatatctac gatgtaacat atacatagga
    14641 agcaccgtta tcaagagcgc caaggctatc aaccagataa gatgaagata caaacctgtc
    14701 acctcacctc cccatataat acgaatcatg cgggtagcgt gatacaaggg agaaaaccaa
    14761 gtcaaatcac caagtattgg gggcaaggaa gtaatgggaa agaaggtatc tgaaaacata
    14821 taaagaggac ggattaccaa aacattgtag taattcagaa attccctaga cggtgccaag
    14881 taggtaaaga ttagtcctaa aacaccaaac aaataaccca ctataaataa aatcagagga
    14941 atcaataaca tcaagacatg aaaatgcgct gtgataagca tggaaatcag ccaaaaaatc
    15001 ccaccgaaaa tcactgcacg aatacctgcc cagatagcct gacccaccac aatatcactc
    15061 gtattgattg gcgtcatcaa catagcatca taagtctttt caatcttata ctggataaag
    15121 gcattgaccg ttgtttctgc ggtggccgca gacatggcag tcgcagcaat taaacctgta
    15181 atgacaaaat cacggtagag cataccgtta acatgcgtca agtaggcacc aactccaaat
    15241 cccattgcta aaagataaaa gagggggtcg ataaggttgg ggacaattga aattttaaat
    15301 aaatttctaa aactcatgta gttgcgtacc acaacgtgtc cgatggactg aaatgataac
    15361 ttaaacatgc aagtcctcct tctctgtccc agtcaacccc aaaaaaagcg tctcaaggtt
    15421 gtcagcatca tacttgatga gcaagtcttc tacagttcct tcttctttga tagtcccttg
    15481 gtggagcatc agcaccctat ctgtcaaata ttcaatctca ttcatatagt gggaagtaat
    15541 aatgatagaa acacctaatt ccttcaactc caaaagttta tcccaaataa tattgcggga
    15601 ttgaatgtct aaaccaactg tcggttcatc taaaatgata atatcaggcc gattgatgag
    15661 agctcttgcc aagacaagac gtcgtcgcat cccacccgac agctgattca caatcttttg
    15721 cgcatgtttg ctcagttgaa caaaatccaa gagagaatcg attctcttcc taagttcgac
    15781 agatgagata ccataacata gaccgtgagc aaaaagatta tcataaacat tcaaggtcat
    15841 atccagcata tcctcctgcc ctacaatacc cagacaagat ttactcttac gacgattggt
    15901 ttcaatattt tgccccaaga tatcaatctc tcctgaggaa attgaggtca gtgagtaaat
    15961 catctttaaa gtggatgttt tgccagcacc gttgattccc aagataccca aacactctcc
    16021 ttctcccaat tcaaagctaa ttcccttgac agcttcataa gaaccatatt gcttttttag
    16081 atttttaaca cttaacttct tcactctttc tttcccccac aaatagagca tgttcgatac
    16141 tttgttaatt catctcactt ttgaaaaaat gttgagaatg taatcttaag attaacgtcc
    16201 ttcaactgtg gatactgctg caattacttt tgtaatttta cctccattta aactcagaca
    16261 ataaaattta aaatattctc tagtaaaac
//
LOCUS       DAVMJI010000042        15046 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.043, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000042 DAVMJI010000000
VERSION     DAVMJI010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.043"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..741
                     /locus_tag="VYR58_001783"
     CDS             <1..741
                     /locus_tag="VYR58_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV3622890.1"
                     /translation="APKPETPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNAN
                     GAMATGWAKVNGLWYYLNSNGAMATGWLEYNGSWYYLNANGAMATGWLEYNGSWYYLN
                     SNGAMATGWLQYNGSWYYLNANGAMATGWLEYNGSWYYLNSNGAMATGWLQYNGSWYY
                     LNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKANQWFKVSDK
                     WYYVNGLGALAVNTTVDGYTVNENGEWV"
     gene            1141..2262
                     /gene="mnmA"
                     /locus_tag="VYR58_001784"
     CDS             1141..2262
                     /gene="mnmA"
                     /locus_tag="VYR58_001784"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV3622891.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTTLLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLKKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTRDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2403..2856
                     /locus_tag="VYR58_001785"
                     /pseudo
     CDS             2403..2856
                     /locus_tag="VYR58_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            2866..4779
                     /gene="mnmG"
                     /locus_tag="VYR58_001786"
     CDS             2866..4779
                     /gene="mnmG"
                     /locus_tag="VYR58_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV3622892.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDKILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDAVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4968..5057
                     /locus_tag="VYR58_001787"
                     /pseudo
     CDS             4968..5057
                     /locus_tag="VYR58_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(5158..6837)
                     /locus_tag="VYR58_001788"
     CDS             complement(5158..6837)
                     /locus_tag="VYR58_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV3622893.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQGEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6839..7072)
                     /locus_tag="VYR58_001789"
     CDS             complement(6839..7072)
                     /locus_tag="VYR58_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV3622894.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7454..7675
                     /locus_tag="VYR58_001790"
     CDS             7454..7675
                     /locus_tag="VYR58_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622895.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7888..8040)
                     /gene="cibB"
                     /locus_tag="VYR58_001791"
     CDS             complement(7888..8040)
                     /gene="cibB"
                     /locus_tag="VYR58_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV3622896.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(8042..8227)
                     /gene="cibA"
                     /locus_tag="VYR58_001792"
     CDS             complement(8042..8227)
                     /gene="cibA"
                     /locus_tag="VYR58_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV3622897.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8405..9088
                     /gene="tsaB"
                     /locus_tag="VYR58_001793"
     CDS             8405..9088
                     /gene="tsaB"
                     /locus_tag="VYR58_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV3622898.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYVGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            9085..9522
                     /gene="rimI"
                     /locus_tag="VYR58_001794"
     CDS             9085..9522
                     /gene="rimI"
                     /locus_tag="VYR58_001794"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV3622899.1"
                     /translation="MIEIKRIQKHSDLAQAIYAVMIAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9512..10522
                     /gene="tsaD"
                     /locus_tag="VYR58_001795"
     CDS             9512..10522
                     /gene="tsaD"
                     /locus_tag="VYR58_001795"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV3622900.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10562..11868)
                     /locus_tag="VYR58_001796"
                     /pseudo
     CDS             complement(10562..11868)
                     /locus_tag="VYR58_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(12201..12495)
                     /locus_tag="VYR58_001797"
                     /pseudo
     CDS             complement(12201..12495)
                     /locus_tag="VYR58_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12602..12895)
                     /locus_tag="VYR58_001798"
                     /pseudo
     CDS             complement(12602..12895)
                     /locus_tag="VYR58_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            13138..14312
                     /locus_tag="VYR58_001799"
                     /pseudo
     CDS             13138..14312
                     /locus_tag="VYR58_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            14305..>15046
                     /locus_tag="VYR58_001800"
     CDS             14305..>15046
                     /locus_tag="VYR58_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV3622901.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFN"
BASE COUNT         4458 a         2795 c         3447 g         4346 t
ORIGIN      
        1 gctcctaaac cagaaactcc aaaaacaggc tggaaacaag aaaatggtat gtggtacttc
       61 tacaatacgg atggttcaat ggcaacaggc tggctacaaa ataatggctc atggtactac
      121 ctcaacgcta atggtgctat ggcaacaggt tgggctaaag tcaacggctt atggtattac
      181 ctcaacagca atggtgctat ggcgacaggt tggctagaat acaatggttc atggtactac
      241 ctcaacgcta atggtgctat ggcgacaggt tggctagaat acaatggctc atggtactac
      301 ctcaacagca atggcgctat ggcgacaggt tggctccaat acaatggttc atggtactac
      361 ctcaacgcta atggtgctat ggcgacaggt tggctagaat acaatggctc atggtactac
      421 ctcaacagca atggcgctat ggcgacaggt tggctccaat acaatggttc atggtactat
      481 ctaaacgcta acggcgctat ggcaacaggt tgggctaaag tcaacggttc atggtactac
      541 ctcaacgcta acggttcaat ggcaacaggt tgggtgaaag atggagatac ctggtactat
      601 cttgaagcat caggtgctat gaaagcaaac caatggttca aagtatcaga taaatggtac
      661 tatgtcaatg gcttaggtgc ccttgcagtc aacacaactg tagacggata tactgtcaat
      721 gaaaacggtg aatgggttta agccgattaa attaaatcat gttaagaaca tttgacattt
      781 taattttgaa acaaagataa ggttcgattg aatagattta tgttcgtatt ctttaggtac
      841 ctgtcttatg atttcaggaa atgtcattaa aaaaacgact ccttttctct aacttggaaa
      901 atagattaga gaaaatgggt tgttttattt attatagtta tttgaatgaa gataagaaga
      961 aggtatactc acatcattca caaatctgta tattgactat aagttttaaa aaacaatttt
     1021 taagctcttc cttgtcttct ctaaccaagc gtgttataat gaatactgct caagcgacct
     1081 tcaatcgtga agcacacacg accttcaatc gtgaataaac gaatagatgg gagacttacc
     1141 atgagtgata actctaaaac acgtgttgtc gtggggatga gtggtggtgt tgattcgtcg
     1201 gtgacgactc ttcttctcaa ggagcagggc tacgatgtga tcggtatctt catgaagaac
     1261 tgggatgaca cagatgaaaa cggcgtctgt acggcgaccg aagattacaa ggatgtggtt
     1321 gcggtggcag accagattgg cattccctac tactctgtca attttgaaaa agagtactgg
     1381 gaccgcgttt ttgagtattt cctagcggaa taccgtgcgg gacgcacgcc aaatccggac
     1441 gttatgtgca acaaggaaat caagttcaag gcctttttgg actatgctat gaccttgggg
     1501 gcagactatg tagcgactgg gcattatgct cgagtggtgc gtgatgagga tggcactgtt
     1561 cacatgcttc gtggcgtgga caatggcaag gaccagacct atttcctcag ccaactttcg
     1621 caagaacaac ttcaaaaaac catgttccca ctaggacatt tgaaaaagcc tgaagttcga
     1681 aaactagcag aagaagcagg tctttcgact gctaagaaga aagactcgac agggatttgc
     1741 tttatcggag aaaagaactt taaaaacttc ctcagcaact acctgccagc tcagcctggt
     1801 cgcatgatga ctgtggatgg tcgcgatatg ggcgagcatg caggtcttat gtactatacg
     1861 attggtcagc gtggcgggct tggtatcggt ggacaacacg gtggtgacaa cgcgccgtgg
     1921 ttcgttgtcg gaaaagacct gagcaagaat attctctatg taggccaagg tttctaccat
     1981 gattcgctca tgtcaactag cctagaggct agccaagtcc actttactcg tgatatgccc
     2041 gaggagttta cgctagaatg tacggctaaa ttccgttacc gtcagcctga ctctaaggtg
     2101 accgtccatg tcaaaggaga caaggcagaa gttatctttg cggaaccaca acgcgcgatt
     2161 acaccaggac aggcagttgt cttttacgat ggcgaagagt gtctaggtgg cggtttgatt
     2221 gacaatgctt accgcgatgg acaagtttgt cagtacattt agattgacaa attttctcaa
     2281 tttgctacaa taataacagc aatagaaatg atggtcaaag ctcatggatg ttgcaggctt
     2341 ttttgtcctg cacttctttg gagttttgac tgtttttgtg tcgtttaagg gaaaggacaa
     2401 gaatgactca acaagacttt cggacaaaag tagacaatac ggtttttggt gttcgggcga
     2461 cagctttgat tcttcaaaat cgcaagcttc tagtcaccaa agacaagggc aagtattaca
     2521 ctatcggcgg tgcgattcaa gttaacgaaa aaacggaaga cgcggtagtc cgtgaagtga
     2581 aggaagaact gggtgtcaaa gctcaagctg ggcagctagc ttttgtggtt gaaaatcgtt
     2641 ttgaacagga cggtttttcc tatcacaata tcgaatttca ttatctggtg gacttgctgg
     2701 aggatgcccc attgaccatg caggaagatg agaaaaggca gccctgtgag tggattgact
     2761 tggataagtg aggatatcca gctagttcca gcctttttaa aaacggccct accagattgg
     2821 gaaggccaac taagacacat tcatcgtgag gaataggaga gaaacatgac ttatcatttt
     2881 actgaagaat acgatattat tgtaattggt gcgggacacg ctggggttga ggcttccttg
     2941 gccgctagcc gtatgggctg taaggttcta cttgcgacca tcaatattga aatgctggct
     3001 ttcatgcctt gtaatccctc tatcggtggt tctgctaagg ggattgtcgt acgtgaagtc
     3061 gatgccctcg gtggcgagat ggccaagacc attgacaaga cttacatcca gatgaagatg
     3121 ctcaacacag ggaagggtcc tgctgttcgt gcccttcgtg cgcaggctga caaggaactt
     3181 tactctaagg agatgcgcaa gacagttgaa aatcaagaaa atctgaccct tcgtcaaacc
     3241 atgattgata agattttggt ggaagatggc aaggttgtcg gtgttcgtac agcgactcat
     3301 caagagtatg ctgctaaggc tgttattgtg acgacaggga ctgctctccg tggggaaatt
     3361 atcatcggag acctcaagta ctcatcaggt cctaaccaca gcttggcttc tattaaccta
     3421 gctgacaatc tcaaggaact gggtctcgaa atcggtcgtt tcaagacagg aacccctcca
     3481 cgtgtcaagg cctcttctat caactacgac gtgacagaaa tccaaccagg agacgcagta
     3541 cctaatcatt tctcatacac ttcacgtgat gaggattatg tcaaagatca agtgccatgc
     3601 tggttgacct ataccaatgg taccagtcat gagattattc aaaacaacct ccaccgtgcg
     3661 cctatgttta caggtgtggt caagggagtg gggcctcgtt actgtccgtc gattgaagac
     3721 aagattgtgc gctttgcgga caaggaacgt caccaactct tccttgagcc agaagggcgc
     3781 aatactgagg aagtctatgt tcaaggactt tcaaccagtc tgcctgagga tgtccagcgt
     3841 gacttggttc attccatcaa aggtttggaa aatgcagaga tgatgcggac aggttatgct
     3901 attgagtatg atatggtctt gcctcatcag ttgcgtgcga ctttggaaac caagaaaatc
     3961 tcaggtctct tcactgctgg tcagacaaat ggaacgtcag gttacgaaga ggcagcaggc
     4021 caagggatta tcgcaggtat caatgcggct ctaaaaatcc aaggcaagcc tgaattgatt
     4081 ctaaaacgaa gtgacggtta tatcggggtg atgatcgacg acttggtgac caagggaacc
     4141 attgaacctt accgtctctt gaccagtcgt gctgaatatc gtctcattct tcgccatgac
     4201 aatgctgata tgcgcttgac tgagatgggc cgtgagattg gccttgtgga cgatgaacgc
     4261 tgggctcgtt ttgaaatcaa gaaaaatcaa tttgataatg agatgaaacg cctagacagt
     4321 atcaaactca agccagtcaa ggaaaccaat gctaaggttg aggaaatggg cttcaagccg
     4381 ttgacagatg cggtgacagc caaggaattc cttcgccgtc cagaagtttc ttaccaagat
     4441 gtggtggcct tcatcggacc agctgcagag gaattagatg acaagattat cgaattgatt
     4501 gaaacagaaa tcaagtacga aggctatatt tccaaagcca tggatcaggt tgccaagatg
     4561 aaacgtatgg aagaaaaacg cattccagcc aatatcgact gggatgacat cgattctatt
     4621 gcgacggaag ctcgtcagaa gttcaaactc atcaatccag aaaccatcgg ccaagccagc
     4681 cgtatttcgg gagtaaaccc agcagatatt tctattttga tggtgtatct ggaaggtaaa
     4741 aatcgtagta tttctaaaac tcttcaaaaa tcaaaatgat acgtcgtagg cttcttacga
     4801 atgagttcaa agcttggctt tgattcatct ccaacctccc atagttcccc gaactatggg
     4861 agctaactca agttatgcat tttcctagcc ttctggtctg attttcattg agttttaatc
     4921 taaaaagaaa gcatagagaa aaacagctcc gaagacgggg ctgttttgtt gatttgtact
     4981 caatgaaaat caaagagcaa actaggaagc tagccgtagg ttgctcaaag cactgctttg
     5041 aggttgtgga tagaactgac gaagtcagct caaaacaccg ttttgaggtt gtggatagaa
     5101 ctgacgaagt cagtaacata tatacggcaa ggcgaagctg acgtggtttg aagagtatta
     5161 ttcttcatct ggtgtgagga tcatcgggat gatgatcggt tcacgttcgg tattttcata
     5221 gaggaagggg cgaatagcgt tgacaatggc accattgaca gattgcacgc tagcatcctt
     5281 atttttcagt gcgatacgaa tggcattgaa gaggatacgc tggctttgac gaatcaagtc
     5341 gccagactct ctcatgtaga caaagcctcg gctgaggatg tctggaccag atagaatcat
     5401 ctgcgatttg aagtcaacag ttgcgactgc cagaacgaca ccgtcttcag atagatcgcg
     5461 acgatctttg aggacagctg cgccaatttc accgatacga tttccatcga catagatatc
     5521 ttgggcgttg aaatggcctg cgatacgagc tgagtcagca gtaagggcaa gcacatcgcc
     5581 attgctcatg ataaagatat tgtccttctc aacaccagta tccactgcta gtccagcgtg
     5641 gactttttgc atgcggtatt caccgtggac aggcatgaag tattttggct taatcaagca
     5701 gagcatgagt ttttgctctt gctgaccacc gtgtccagat gtatggatat tgttcacttt
     5761 accgtggata acttcgacac cagcttcaga aatgatgtta atcagcttgt tgacgctagt
     5821 agtgtttcca gggatgggac tagaagagaa gataacggta tcacctggtt gtaattgtac
     5881 ttgacggtgg gttccgttgg cgatacgaga gagggctgcc ataggctcac cctgactacc
     5941 tgtacagagg ataagaactt ctcctgcagg ataatctttg atttcatttg gctcgataaa
     6001 ggttccctta ggagctttga tgtagccaag atcgattccg ttgacaatgg ccttttccat
     6061 agaacgacca aagaccgcaa tcttgcgtcc agtcttaaca gcagcttctg ttgcctgctg
     6121 gagacggaag atatttgagg caaaggatgc aaagatgata cgtccttcaa taccttggat
     6181 aatcttcata atggactgac caacgacttt ttcagagttg gtaaaggttg gtacttccgc
     6241 atttgtcgag tcagacagga gacagagcac gccttcttca ccaagcgcag ccatacgatg
     6301 caagtccgca ggttctccaa ctggagtaaa gtcgaactta aagtcacccg tacagacgat
     6361 tttcccttga ggagtatgaa tgacaatccc caaaggctct ggaatagagt gagtcgttct
     6421 aaagaaagtt gccttgagat ttttaaaggt caactcggtg ttgtggttga tttcgtaaag
     6481 tttggcgttg cgcaagaggc cgtgttcttc gagtttccca cggatcaaag ccaaggcaag
     6541 cggtccagca taaataggga catttgcttg cttgagtagg aacggaatcc caccaatgtg
     6601 gtcctcgtgt ccgtgtgtga ttaaaacagc cttgacgcgg tcgatattgt ctacgatgta
     6661 agagtagtca ggaatgacat agtcgatacc aagcaagtca tcttctggga atttaatccc
     6721 agcatcgacg atgataatct cgccttggta ttcaattccg taagtgtttt tcccgatttc
     6781 tcctagacca ccgatggcaa aaacgccgac ttcttcaggt ttaagagtgt aggccatatt
     6841 agaactccgt aatttcgaag gcgccagttt ctttttcgta atcgagcaat ttgtcagaca
     6901 agagttcgat atattcgata ttgtactctg ggcgattttc ttcgacaagt tggcgagcag
     6961 tgatacggcc ctcaagttct gagctggcat cgatgtctag gtaaagcgcg cgtgttgttt
     7021 cacggcgtgg gctacgttct tttgtttctt gataaaaaac tttgtaaatc atatagttcc
     7081 tttctattta caggtcagct tattccaaac ttttagcaga tatttgcttg atttcattcc
     7141 attttgtgtc tagattgacc ttgattcgtt acaattattt caattatacc acaaaatgaa
     7201 aaattagtaa aagacggaaa cgagaaagtt aggggacgat ttcttcggta agcgtttgcg
     7261 aaaataaaga aaatgtatta tgttgataac ggaagtgaaa tttattgctt gtcataattc
     7321 catatagatt ttaagtcaag gaggttgccc tatgtataac ttatttgctt ttgctatcgg
     7381 agttcgtttg ctagctttta tcgtttttgt tttgcgttta tggaggaaat cttctatttg
     7441 ccaaactgga acgatgacaa accaagttct tgaggaaaat tacctttgtg actctctact
     7501 cgctttttct cctcctcgtg acctatgtcg tttggtttgt attttacttt ggattaaatg
     7561 cttagatgcc ctgcttatgc tggggttttt tgtttgggga tgtagagata gtagatttac
     7621 gacacgaaaa ttccacccca tctatcaaga tgaggtggtc tttgcatttt tctaaaatga
     7681 tatgacaatg gaattttcaa agcttattat ttttatggga gtcattgttc tgctcaaaaa
     7741 tagagttgaa gcataaaaat aaaacaatac aaacagataa atcgaatggt aaagggatgg
     7801 tagtaatgtt caaatcattg agaatgctga gcaaactgta agagatgaag acaataaaat
     7861 ttatccttct aaaaatgtgt ttcttatcta gcatgactta ccaaactttt tacgaaggtc
     7921 ttttccaatg gtataacctg ccataaataa agcgatacca acacctacac caaagccacc
     7981 cttgatttct tgcaattcct tattagaaat ttcacgacag ttgttcaaat ctttcatcat
     8041 attaatctcc tcctaaaaaa taaccagctg ccaaaccaga acctataagt gctgttccac
     8101 ctgcaatagc tttccaagat actgctactc caaagataac caagggagcg agaccgccat
     8161 caatatctga taattcattt tcagataagg ataaaaattg attgtcaaga atgtcaaaat
     8221 ttgtcattga actttcctcc ttttttcttg ttcactttta tattcggaaa agaaaaggaa
     8281 aagtgagcat ttttttaaat tatttttagt taagtgaggg cactcttgtc tgggggcaaa
     8341 gaaaattccc atgtgccagc ttttgtagta taatagtaag cagacaaaaa gataggaatg
     8401 tgttatgaaa gtattagctt ttgatacgtc cagcaaggct ctttctctcg ctattttaga
     8461 ggacaagcag gttcttgccg agacgacgat taatattaag aaaaatcaca gtattactct
     8521 tatgcctgcc atagattttt tgatggcaag tttggattgg acacccaagg atttggaccg
     8581 aatcgtggta gctgaagggc cgggtagcta cacaggcttg cgaattgcgg tagccactgc
     8641 caagactttg gctcatactc tgaacatcga gttagttggt atgtctagcc tcttggctct
     8701 ggtaccctac caacaagaag gcttgttcgt ctctttgatg gatgcgcgtc gcaacaatgt
     8761 ttatgtagga ttttatgaaa atgctaaacc cgtcatgcca gaagctcact taccctttga
     8821 gcgagtgatt gagttaatca agggtgctag tcaggttacc tttgtcggag aagttggccc
     8881 ctttgttgag cagattcaag aatacttgcc aaggactaat ttcaaagaaa ccttgccaaa
     8941 tgcagctaat ctagctctat gggcctggga caaggaagca gactccttgc atgattttgt
     9001 gccgaactac ctcaagcgtg tcgaagctga ggaaaactgg ctcaagaatc acaccgagtc
     9061 tggcgagtct tacattaaac gcttatgata gaaatcaaac gaatccaaaa acattctgac
     9121 ttggctcaag ccatctacgc tgttatgata gctgtttacc cagtcagtcc ttggacgctg
     9181 gaacaaatcc aagcagacct gtcccaagac caaacttggt atgctttggc ttatgatggg
     9241 gcagaagtga ttggatttct agctgtgcag gagaatcttt ttgaagcaga agtcctgcaa
     9301 atcgctgtca aaggagctta tcagggtcag ggaattgcgt cagccttgtt tgctcaattg
     9361 ccgacagaca aggaaatttt cctcgaagtc agacagtcaa atcaacgagc gcaagcattt
     9421 tacaagaaag aaaagatggc agttatcgct gagcgaaagg cctactacca tgacccagtc
     9481 gaggacgcca ttatcatgaa gagagaaata gatgaaggat agatatattt tagcatttga
     9541 gacatcctgt gatgagacca gtgtcgccgt cttgaaaaac gacgatgagc tcttgtccaa
     9601 tgtcattgct agtcaaattg agagtcacaa acgttttggt ggcgtagtgc ccgaagtagc
     9661 cagtcgtcac catgtcgagg tcattacagc ctgtatcgag gaggcattgg cagaagcagg
     9721 gattaccgaa gaggacgtga cagctgttgc ggttacctac ggaccaggct tggtcggagc
     9781 cttgctagtt ggtttgtcag ctgccaaggc ctttgcttgg gctcacggac ttccactgat
     9841 tcctgttaat cacatggctg ggcacctcat ggcagctcag agtgtggagc ctttggagtt
     9901 tcccttgcta gcccttttag tcagtggtgg gcacacagag ttggtctatg tttctgaggc
     9961 tggcgattac aagattgttg gggagacacg agacgatgca gttggggagg cttatgacaa
    10021 ggtcggtcgt gtcatgggct tgacctatcc tgcaggtcgt gagattgacg agctggctca
    10081 tcaggggcag gatatttatg atttcccccg tgccatgatt aaggaagata atctggagtt
    10141 ctccttctca ggtttgaaat ctgcctttat caatcttcat cacaatgccg agcaaaaggg
    10201 agaaagcctg tctacagaag atttgtgtgc ttccttccaa gcagcagtta tggacattct
    10261 catggcaaaa accaagaagg ctttggagaa atatcctgtt aaaaccctag ttgtggcagg
    10321 tggtgtggca gccaataaag gtctcagaga acgcctagca gccgaaatca cagatgtcaa
    10381 ggttatcatc ccccctctgc gactctgcgg agacaatgca ggtatgattg cctatgccag
    10441 cgtcagcgag tggaacaaag aaaacttcgc aggctgggac ctcaatgcca aaccaagtct
    10501 tgcctttgat accatggaat aaagagtggc tctttgtcaa gtgtagtggg taggcgaaaa
    10561 gctacaatct ggagagtacg aaattcgtac tctctttttt gatgttcaaa gtcatcaaaa
    10621 tccgtttttt aaaattgtta aagttccgaa aaccaaaggc tttgcgcttg ataaccttaa
    10681 taaaattatt ggtcgcttca agtttagcgt tggaataagg cagcttaagt gcgttgataa
    10741 tcttatctct atcccttaaa aaagtccaaa agaccgtttg aaaaagcgga tgaaccgttg
    10801 gcagttcttg ctcaatcaat ccaaagaaat ggttggcatt cttctcttga aaatgaaaga
    10861 gcaggagttg atagagttcg tagtgaacct gtaatccctc agagtaagaa agcagcttat
    10921 ctcgtacttc ccgatgggtt aagtgcattc gaaacgtggg ctgatagaat cgtttctgac
    10981 agagcttgaa gctatcctgg tgtagtaaat cagtccagtg gactgattta gcccgagcct
    11041 agaaacgaaa aagcgagggt tccaaaagcg cttgagcgcc cgatactcca aggattttcg
    11101 gtcaaattgg ttcatgattt ggattcgtac tcggttcata gctcggctca gatgttggac
    11161 aatgtggagg cggtcaagaa caatcttcgc ctttggaaag agttgcttag cgagccgata
    11221 ataagggctg tacatgtcca tggtgatgac ctcgaccagc tcccgaacct ctctctgata
    11281 gcgttggaaa tggtttcgaa tcaccgcatg agttcgcccg tctaaaattg cgaggatgga
    11341 tttggactca aaatcttggg caatgaagct cattttgctc tttttgaagc tatactcatc
    11401 ccaactcata acttttggca acttggtcca atcggtttca aacttaaatt ccctcagttt
    11461 tcggatgacg gtggaagttg agaccgccaa tctgtgggca atctcagtca tagactgctt
    11521 ttcaaggagg agctgagcga ttttttgtct caccatgttg gaaatctggc aatttttctt
    11581 gacaatggat gtttgagaaa cgaccacctt aaggcaattc ttgcactgaa agcggcgctt
    11641 tttgagatgc agtaccgtgg gtaaaacctg acagtcgaga agcggaattt tagaggcttt
    11701 ctggaagtcg tatttgatca tcttcccttg acaatgagga caaggaggag cgggggaatc
    11761 caactttgcc tgaacgacta gatgggtttg gtatttcaga acagacaaga ttttgatatt
    11821 tttgtcttcc aatccgagca aatctgtggt attcttaagt tgttccatat gaaccctttc
    11881 taatgagttg gttagacgct tttcattata ggtcatatgg ggcttttttt ctacaagaaa
    11941 cgaccctata attcctgggg tgggattacc cactacagaa attatagagc caaagcattc
    12001 caaagtcttg tctgactctg gaatgttttc tgttcacagt tgttttgtaa ctgcctaata
    12061 agtaaccgcg ctataacgag gtatctaccg agattgtcaa ttctccagta tactgttata
    12121 aaaaacaaaa ctggaggatt tttttatgtc cccccatcgt cccatcgact gttccgtagc
    12181 tgcccaataa cggagtataa tcagctgaaa caagaatagg acaaaagtgc ctcaagaaaa
    12241 gcatcgtaat ttgacaatat tattctgaga tgtttttgat gtaagcccat attttctcaa
    12301 tgggattata ctcgggtgaa tagataggaa gtggtaacag tctatgccct gctccttaca
    12361 catgttcatt ctgtgaaacc ttgcattgtc cataatgata agggatggtg tatctaaagt
    12421 aggtagtaag aatttttgga agcaagcttc gaaaaagtca ctcgtcatcg tatctttata
    12481 ggtcatcgga gccatagtat attgaaacaa aaaagggcat tagtacttct ataacagtat
    12541 cgcaatctct ggtgtgcgtt gtctcgatct taattcaaat aattatatct tcttccagag
    12601 agactaactg cctgctcaag gctcgatcat attcgagata aaaataggtc ttaacccctg
    12661 tctcataaat ataaatagga gtcaggtagc ttaagtgatt caattcttta aggaaccgat
    12721 ttactttttc tgggtcttgt tcgcagtagg tacggctctt ttttagacta tatcccatag
    12781 cctttagagc gtaatgaata gttgttggag gacagttgaa ttcagcagct atttcagtca
    12841 aataagcatc gggatgagtt tcaatataga tctttaattt atctctatca actttttcaa
    12901 ttaatagtgg aagttttctt aaagttagtg tattgaaacg tttttataca gtgctaaaat
    12961 ttgaagtgta gtgcagatat atttgtaata gtattataga aattctttga agaaggtcga
    13021 gacaagagaa aataggtatc tttgagatat aagcatgatt tactataaaa ttattgagtt
    13081 attcataaaa atttctctat caaatatcat aatgcgtcgt ttaaggagat ggttacaatg
    13141 caatatagtt gtggaaaaat aaatattaat atccctgatg gatatggaga cattaaggat
    13201 atagtgtttt cggctcatat tatagttagg tataataatg gacattgtgg aggtatagat
    13261 ccgcatataa ttggactttg taaaaagcag atcagaagga tgtctctata tcctattttg
    13321 ataatcgtat ctagagattc aaaggttatt gatgattata aaaatttaga tattgcctat
    13381 gttgattgta ctcaatgttc aaataatttt gaaactgcct tacacgttaa aaatatttta
    13441 aaattattaa aaatccaact tatacactgt catggctact caactaatta ttttttatat
    13501 atgttaaaaa aacttgacaa gaatggattt ggaaaggtta agacagtgat aacatgccat
    13561 ggatgggttg aatataactt aaaaaagaaa ttcttgactt attttgattt ttggacatat
    13621 tctatgggag atgcttttat ttgtgtatct gaaactatga aaaaaagatt ggagagtata
    13681 ataaaaaaat aagaagatag ttgcaataaa taacggaatt aatgtatcaa atagcgattt
    13741 agatgtagta ggtgttcaag actttaaaaa agaattttgt attccaaata acaaaaaaat
    13801 catttgttat gttgaaaggt tggatccaga aaaaaggccg gatagattcc ttgaatttgc
    13861 agaaaaatta tttttagtca gagaagatgt gatttttatt atggctggaa atggtagtat
    13921 gtgggctgct ttgaaagaaa aaatttgcca tttgaaatgt agagataatt tcaggttact
    13981 tggtgaaatc tatccagcta ctatagttta ccaaatatcg gatttattgt atattccttc
    14041 tgatacagaa ggaataccta tgtgtgtttt agagtcaatg tcacaaggaa ctccggtttt
    14101 agctagtaat gttggcgggt taagtgaaat tattgaacat agggttgatg gatttttatt
    14161 tgagaaggaa gatgttgagg gagtgtgtgc ttgtgctaat tttttactca atgattctga
    14221 gtatttgaaa tatataggtg agaatagtaa atcaaaaata agaaaacatg agagtatatg
    14281 atgaattatt agagaagagt agtcatggat aggaatatag atcaagaatt agtaagtatt
    14341 ataataccaa cacataatag gtatgaatct ctgattagag ctgtgaaaag ttgtttacat
    14401 caaagttata aaaatatcga agttataatt attgatgata attatagtaa tgtaaattta
    14461 agaaataaaa ttatccatca atttggctat accaatcata gaattaagtt aattttaagt
    14521 aatgaagatt taggtgcaac taatgccaga aacataggta tcaaaaattc tagaggtaag
    14581 tatatatcat ttttagacga tgatgatgaa tatatgccag atcgaatttt aaagttgatg
    14641 gcttgtttta aaaagagtag aatgaagaat ttagctttag tttatagtta tggaataata
    14701 atttatccaa atggtacacg agaagaggag aagaccgatt ttgttggaaa tcccttgttt
    14761 gttcaaatgg ttcacaatat agcaggtacg tcattttggt tgtgtaaaaa agaggtgcta
    14821 gaattaatta atggttttga gaaaatagat tcacatcagg acggtgttgt tttattaaaa
    14881 ctacttgctc aaggatacca aattgatata gtgcgagaat tcttggtgaa ttactacgct
    14941 cacagtaaag aaaacggtat cactggagtg acacaaaaaa caattaatgc agatgaagaa
    15001 tattataatt actgtaggaa atattttaat ttattgagtt tcaacg
//
LOCUS       DAVMJI010000043        13478 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.044, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000043 DAVMJI010000000
VERSION     DAVMJI010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.044"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            137..2317
                     /locus_tag="VYR58_001801"
     CDS             137..2317
                     /locus_tag="VYR58_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV3622902.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2369..3184
                     /locus_tag="VYR58_001802"
     CDS             2369..3184
                     /locus_tag="VYR58_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV3622903.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            3324..4667
                     /locus_tag="VYR58_001803"
     CDS             3324..4667
                     /locus_tag="VYR58_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV3622904.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            4882..6072
                     /locus_tag="VYR58_001804"
     CDS             4882..6072
                     /locus_tag="VYR58_001804"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV3622905.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            6625..7560
                     /locus_tag="VYR58_001805"
     CDS             6625..7560
                     /locus_tag="VYR58_001805"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV3622906.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFTYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            7594..8631
                     /locus_tag="VYR58_001806"
     CDS             7594..8631
                     /locus_tag="VYR58_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV3622907.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            8772..9377
                     /locus_tag="VYR58_001807"
     CDS             8772..9377
                     /locus_tag="VYR58_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV3622908.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            9535..10065
                     /locus_tag="VYR58_001808"
     CDS             9535..10065
                     /locus_tag="VYR58_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV3622909.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            10086..10988
                     /locus_tag="VYR58_001809"
     CDS             10086..10988
                     /locus_tag="VYR58_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HEV3622910.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFADEGVQVNLAVSLHA
                     PNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAE
                     LLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGTDID
                     AACGQLRSNTMKRDRQKAVAAVNP"
     gene            10988..11470
                     /locus_tag="VYR58_001810"
     CDS             10988..11470
                     /locus_tag="VYR58_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV3622911.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GCLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            11472..13013
                     /locus_tag="VYR58_001811"
     CDS             11472..13013
                     /locus_tag="VYR58_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV3622912.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(13068..>13478)
                     /locus_tag="VYR58_001812"
     CDS             complement(13068..>13478)
                     /locus_tag="VYR58_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV3622913.1"
                     /translation="RFYRPTFRMHLTNKEILNKLLSYSQDLKHHYQLYQLLLFHFQNK
                     EPEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNAKLEATNNLIKLIK
                     RNAFGFRNFENFKKRIFIALNIKKERTNFVLSRA"
BASE COUNT         4053 a         2480 c         2962 g         3983 t
ORIGIN      
        1 ctagaaattt tttagaaaaa agtgtaattt ttttataaaa gcctttacaa aaaaaattaa
       61 agtggtataa ttaaatcata gaaagtgcaa acgttttcgt aaaacgtttg cctaaataaa
      121 aataaaggag atttgaatga tgaaagatac attcaaaaat gtcttgtctt tcgaattttg
      181 gcaaaaattc ggtaaggctt tgatggtagt tatcgcggtt atgccggctg ctggtttgat
      241 gatttcaatc ggtaagtcta tcgtgatgat taacccaacc tttgcaccac ttgtcatcac
      301 aggtggaatt cttgagcaaa tcggttgggg ggttatcggt aaccttcaca ttttgtttgc
      361 cctagccatt ggaggaagct gggctaaaga acgtgctggt ggtgctttcg ccgctggtct
      421 tgctttcatc ttgattaacc gtatcactgg tacaatcttt ggtgtatcag gcgatatgtt
      481 gaaaaatcca gatgctatgg taactacttt ctttggtggt tcaatcaaag ttgctgatta
      541 ctttatcagt gttcttgaag ctccagcctt gaacatgggg gtattcgtag ggattatctc
      601 aggttttgta ggggcaactg cttacaacaa atactacaac ttccgtaaac ttcctgatgc
      661 actttcattc ttcaacggga aacgtttcgt accatttgta gttattcttc gttcagcaat
      721 cgctgcaatt ctacttgctg ctttctggcc agtagttcaa acaggtatca ataacttcgg
      781 tatctggatt gccaactcac aagaaactgc tccaattctt gcaccattct tgtatggtac
      841 tttggaacgt ttgctcttgc catttggtct tcaccacatg ttgactatcc caatgaacta
      901 cacagctctt ggtggtactt atgacatttt aactggtgca gctaaaggta ctcaagtatt
      961 cggtcaagac ccactatggc ttgcatgggt aacagacctt gtaaacctta aaggtactga
     1021 tgctagtcaa tatcaacact tgttagatac agtacatcca gctcgtttca aagttggaca
     1081 aatgatcggt tcattcggta tcttgatggg tgtgattgtt gctatctacc gtaatgttga
     1141 tgctgacaag aaacataaat acaaaggtat gatgattgca acagctcttg caacattctt
     1201 gacaggggtt actgaaccaa tcgaatacat gttcatgttc atcgcaacac ctatgtatct
     1261 tgtttactca cttgttcaag gtgctgcctt cgctatggct gacgtcgtaa acctacgtat
     1321 gcactcattc ggttcaatcg agttcttgac tcgtacacct attgcaatca gtgctggtat
     1381 tggtatggat atcgttaact tcgtttgggt aactgttctc tttgctgtaa tcatgtactt
     1441 tatcgcaaac ttcatgattc aaaaattcaa ctacgcaact ccagggcgca acggaaacta
     1501 cgaaactgct gaaggttcag aagaaaccag cagcgaagtg aaagttgcag caggctctca
     1561 agctgtaaac attatcaacc ttcttggtgg acgtgtaaac atcgttgatg ttgatgcatg
     1621 tatgactcgt cttcgtgtaa ctgttaaaga tgcagataaa gtaggaaatg cagagcaatg
     1681 gaaagcagaa ggagctatgg gtcttgtgat gaaaggacaa ggggttcaag ctatctacgg
     1741 tccaaaagct gacattttga aatctgatat ccaagatatc cttgattcag gtgaaatcat
     1801 tcctgaaact cttccaagcc aaatgactga agcacaacaa aacactgttc acttcaaaga
     1861 tcttactgag gaagtttact cagtagcaga cggtcaagtt gttgctttgg aacaagtaaa
     1921 ggatccagta tttgctcaaa aaatgatggg tgatggattt gcagtagaac ctgcaaatgg
     1981 aaacattgta tctccagttt caggtactgt gtcaagcatc ttcccaacaa aacatgcttt
     2041 tggtattgtg acggaagcag gtcttgaagt attggttcac attggtttgg acacagtaag
     2101 tcttgaaggt aaaccattta cagttcatgt tgctgaagga caaaaagttg cagcaggaga
     2161 tctccttgtc acagctgact tggatgctat ccgtgcagca ggacgtgaaa cttcaacagt
     2221 agttgtcttc acaaatggtg atgcaattaa atcagttaaa ttagaaaaaa caggttctct
     2281 tgcagctaaa acagcagttg ctaaagtaga attgtaatat acttgaggtt ggaagctgta
     2341 ttccaacctc ttattttggg agaaaagaat gaaattttta acactcaata ctcacagttg
     2401 gatggagaaa gaagcagagg aaaaattcca gattttgctt gaagatattc ttgaaaagga
     2461 ctatgatttg atttgtttcc aagaaatcaa tcaggagatg acctcgtcag aggtggaggt
     2521 taatgacctt tatcaagctt tgccagcagc tgagcctatt caccaagacc attatgttag
     2581 actcttggtt gaaaagttgt tagagcaagg gaaaaattac tactggacct gggcttataa
     2641 ccatatcggc tatgaccgct accacgaagg tgtggctatc ttgtctaaaa cacctattga
     2701 agccagagaa attttggttt cagatgtgga tgatccaaca gactatcata ctcgccgtgt
     2761 tgccctagct gaaactgtag tcgatggcaa ggagctagca gttgccagtg ttcatctctc
     2821 ttggtgggat aaaggtttcc aagaagaatg ggcacgattt gaggctgtct tgaaaaaatt
     2881 gaacaagcca cttttactag ctggagattt taacaaccca gcaggtcagg aaggttacca
     2941 agctatttta gctagtccat taggcttaca agacgcattt gaagttgctc aagagaaaag
     3001 tggtagctat actgttccgc ctgaaattga tggctggaaa gggaacactg aaccccttcg
     3061 aatcgattat gtctttacta ccaaagagtt agcggtggaa aatttacatg tcgtatttga
     3121 tggtaacaag agtccacaag tgagtgatca ctatggcttg aatgctatat taaactggaa
     3181 ataataactg aaaagaggtt ggaactataa aattccagcc ttttcttact agagaagcta
     3241 ctggaaatag cctaaataag tgagactact gtaatggaat aaaatatggt ataattgata
     3301 agatagatag aatcgaggat gttatgtcat ttacgaaatt tcaatttaaa aactatatta
     3361 gagaagcctt gaaggagtta aaatttacaa ctccaacaga ggtgcaagac aagttgattc
     3421 ctattgtttt ggcaggtcgt gacctagtag gagaatcaaa aacaggttca ggtaagactc
     3481 atactttctt gttaccgatt ttccagcaat tagatgaagc tagcgatagt gtacaagcag
     3541 tgattactgc accgagtcgt gagttggcta ctcaaattta ccaagtagcg cgtcagattt
     3601 cagctcactc agatgtcgaa gttcgtgtgg ttaattatgt gggtggtacg gataaggctc
     3661 gccagattga gaaattggaa agcaatcagc ctcatattgt tattggaaca ccaggccgta
     3721 tctacgactt ggttaaatct ggtgatttag ctattcataa agccaagaca tttgttgttg
     3781 atgaagcaga tatgaccttg gatatgggat tcttggaaac tgttgataag attgctggca
     3841 gtcttccaaa agacttgcaa ttcatggtct tctcagcgac tatcccacaa aaactgcaac
     3901 cattcttgaa aaaatactta tcaaatcctg ttatggagaa aattaagacc aaaacggtta
     3961 tttctgacac cattgataat tggttgattt cgaccaaggg acatgataag aatgctcaaa
     4021 tttaccagtt gactcagttg atgcagccgt atttggcaat gatttttgtt aacactaaaa
     4081 cgcgtgctga tgaattgcat tcatatctga ctgctcaagg cttgaaggtt gcaaaaatcc
     4141 atggagatat tgcccctcgt gaacgcaagc gaatcatgaa tcaggtgcaa aatctggatt
     4201 ttgagtatat tgtcgcaaca gatttagcag cgcgtgggat tgacattgaa ggtgtcagcc
     4261 atgtcatcaa tgatgccatt ccgcaagact tatctttttt tgttcatcgt gttggtcgta
     4321 ctggacgaaa tggcctacca ggtacagcta ttacccttta tcagccaagt gatgactcgg
     4381 atatccgtga gttggagaaa ttgggaatca agtttagtcc taagatggtc aaagacgggg
     4441 aatttcaaga tacctatgac cgtgatcgtc gtgccaaccg tgagaaaaaa caagataaac
     4501 ttgatatcga aatgattggt ttggttaaaa agaaaaagaa aaaagtcaaa ccgggttata
     4561 agaagaaaat tcaatgggcg gttgatgaaa agcgccgtaa aaccaagcgt gctgaaaatc
     4621 gcgctcgcgg tcgtgcagag cgtaaagcta aacgccaaac attttaatag aaattgttgg
     4681 agtattgagc tccaactttt ttatttatga gaacgaacta tctaaaccga aacactacat
     4741 taaagactgc aaattgcgat taaaaatggt ataatgataa agttatatag tcccgataag
     4801 atggtaggta tttattacga agagttttcc tatcagtact ttgtaactct ataacaatat
     4861 tttttaaggg gggacatttt tatgtcagaa cgtaaattat tcacgtctga atctgtatct
     4921 gaggggcatc cggataagat tgcagaccaa atttcagatg cgattttgga tgctatttta
     4981 gcaaaggatc cagaggcgca cgttgctgct gaaacagctg tatatactgg ttctgtccac
     5041 gtttttggtg aaatttctac aaatgcctat gtggatatta accgtgtggt tcgtgatacc
     5101 attgcagaga ttggttatac caatacagaa tatggatttt ctgctgagac ggtgggagta
     5161 cacccatctt tggtggaaca atctcctgac atcgctcaag gtgttaacga agccttggag
     5221 gttcgtggaa atgctgatca agatccactg gacttgattg gagcaggtga ccaagggctc
     5281 atgtttggat ttgcagtaga tgaaacagaa gagctcatgc cattgccaat tgcactcagt
     5341 cataaattgg ttcgtcgtct ggcagaactt cgtaagtctg gagaaattag ctatctccgt
     5401 ccagatgcaa aatcacaagt tacagttgag tacgatgaaa atgaccgtcc ggtacgtgta
     5461 gatacagtcg ttatttctac tcagcatgat ccagaggcca ctaatgaaca aatccatcaa
     5521 gatgtgatta acaaggtcat caaagaagtt attccatctt cttatcttga tgataagaca
     5581 aaattcttta tcaatccgac aggtcgtttt gtaatcggtg gtcctcaagg ggactcaggt
     5641 ttgactggtc gtaagattat tgtagatact tatggtggct actctcgtca tggtggtggt
     5701 gccttctctg gtaaagatgc gactaaggtg gatcgttcag cctcttatgc ggctcgctat
     5761 attgccaaga atatcgttgc agcaggcctt gctaagaagg cagaagtgca gttggcctat
     5821 gctatcggtg ttgcgcaacc tgtttctgtt cgtatcgata ctttcggtac aggaacagta
     5881 gctgaaagtc aacttgaaaa agcggctcgt caaatctttg accttcgccc tgcagggatt
     5941 atccaaatgc tggacctcaa gcgtccaatt taccgtcaaa catcggctta cggtcacatg
     6001 ggacgtacag atattgatct tccatgggaa cgtttggata aggtagatgc tttgaaagaa
     6061 gcagtaaaat aagattttaa gaggggaacg tcctctcttt tttatagttt ttaactatac
     6121 tgggatactg ttctgaaaat ccattttgcg aaagtagaga tttacatgta tagtagattg
     6181 aaactagaat agtacacctc aacttctaaa acattgttag caatcaattt gactgtcctg
     6241 atcgatttct cctgttcttg tttcatttta ctatatttct ttaaaaatga taaaggttga
     6301 gatttctcct cgtaatagat aatcatgggg atatttcaat ccaaagtttt attcgttatc
     6361 acttgactat tgcaaggttt tctagagcaa cagagtcatg gaatggactc atggttgaga
     6421 tttctccttg ttgcttggac ttcattcaaa agtctgttac ccaagccttg ttcaaacttc
     6481 caatacacta gctgttttca tagcatgact tctgtactag actttctttt ccgaataaat
     6541 agatagaacc acagaatcta gtaaacctag aattaaaatt atggtataat attagcaata
     6601 aaagaaatct ggaggattag aatcatggta tcaacgaaaa cacaaattgc tggttttgag
     6661 tttgacaatt gcttgatgaa tgcagcaggt gtggcttgta tgacgataga ggagttagaa
     6721 gaggtcaaaa actcagcggc aggaaccttt gttactaaga cagcgacctt ggacttccgt
     6781 caggggaatc ctgagccacg ctaccaagat gttccacttg gttccatcaa ctctatgggc
     6841 ttgccaaata atggcttaga ctattatttg gattatcttt tagatttgca ggaaaaagag
     6901 tcgaaccgaa ctttcttctt atctctggtc ggcatgtctc cagaggaaac ccatactatt
     6961 ttgaaaaaag ttcaagagag tgattttcgt ggtctgactg agctaaatct ttcctgtcca
     7021 aatgttccag gtaaacctca gattgcctat gattttgaga caacagaccg gattttggca
     7081 gaagtgttta cttacttcac caaacctctt ggaattaaat tgccacctta ttttgatatt
     7141 gttcactttg atcaagcggc agctattttc aacaaatatc cgctcaagtt tgtcaactgc
     7201 gttaactcta tcggaaacgg cctctatata gaagacgaat ctgtcgttat tcggcctaag
     7261 aatggttttg gtggaattgg tggagaatac atcaaaccga ctgctctagc caatgttcac
     7321 gccttttatc aacgtttaaa tcctcaaatc caaattatcg gaacaggtgg cgttctgact
     7381 ggtcgagatg cctttgaaca catcctctgt ggagcaagta tggtgcaggt gggaacgacc
     7441 cttcacaaag aaggcgtcag tgcttttgac cgcattacca atgaactgaa agcaatcatg
     7501 gtggaaaaag gctacgagag cttagaagat ttccgtggga aattgcgcta tattgactaa
     7561 attaaatcga aaaatctgaa gaaaggagag acgatgctag ccattgaaga aagtcagaag
     7621 ttgactttat caaatttacc gagcctgagc ctatttacag ggacagatca gggtcagttt
     7681 gaagtgatga agagtcaagt gttgaaacag attgggtatg attctgctga cctcaacttt
     7741 gcctactttg atatgaaaga agtagtttac aaggatgtgg aactggagtt ggtcagcctt
     7801 cctttctttg cggatgagaa aatcgtgata ttagattatt ttatggatat cacgactgct
     7861 aagaaacgct ttttgacaga tgatgagctt aagtcatttg aggaatacct tgacaatcct
     7921 tctccaacaa ccaagttgat aatctttgca gaaggaaagc tggatagcaa aagacggtta
     7981 gtcaaattac ttaagcgtga tgccaaggcc ttcgatgcag tagaagtaaa agaacaagaa
     8041 ttgcgccagt atttccaaaa gtggagtcag aaacaaggtc tgcagtttac caatcattct
     8101 tttgaaaatc tcctcatcaa gtcggggttt caatttagcg aaatccagaa aaatcttctc
     8161 tttttacagt cctataaggc ggattctgtt atcgaggaag aggatattgt taacgcaatt
     8221 cccaagacct tgcaggacaa tatttttgat ttaactcagt ttattctgac taaaaagatg
     8281 gatcaggcgc gcgatttggt gagagacttg accttgcaag gggaagatga aatcaaacta
     8341 attgcagtca tgctgggaca atttcggact tttactcagg tgaagatttt ggcggagtct
     8401 ggccaaacag aatcgcagat tgcaagtagt ttaggtagtt atctgggacg taacccaaat
     8461 ccttatcaaa tcaagtttgc attaagagat tcgagaggac tttctttgag ctttctgaag
     8521 caagctattt cctatttgat tgagacagac tatcagatta agacaggtct ttatgaaaaa
     8581 ggtttccttt ttgaaaaggc actcttacag attgctagtc aggtcaattg acatttgttg
     8641 aaactacaac ccgcgtcagg attatcttgt cgtgggtttc ttgctgattt gcttatctat
     8701 aagcaaaaaa cttgaaaaaa gtgaatgttt gcgttatcat tttcatatag aaagaaaaag
     8761 aggtattaca gatggctatt atcttaccag aacttccata tgcatacgac gctttggaac
     8821 catacatcga tgcggaaaca atgcatttgc accatgacaa acaccatcaa acttatgtca
     8881 acaatgccaa tgcagcttta gaaaaacacc ctgaaatcgg tgaagacctt gaagccttgc
     8941 ttgctgatgt agaatctatc ccagctgata tccgtcaagc acttatcaac aatggtggcg
     9001 gacacttgaa ccacgctctt ttctgggaat tgatgactcc cgagaaaaca gctccttcag
     9061 cagaactggc agcagcaatc gatgcaacat ttggttcatt tgaagaattc caagcagcct
     9121 tcactgcagc agcaacaact cgttttggtt caggttgggc atggttggtt gtcaacaaag
     9181 aagggaaact tgaagtgact tcaacagcaa accaagacac accaatctca gaaggtaaaa
     9241 aaccaatctt gggcttggac gtttgggaac atgcttacta cgtgaaatac cgcaacgtgc
     9301 gtcctgacta catcaaagct ttcttttcag taatcaactg gaataaagta gatgaattgt
     9361 acgcagctgc taaataatga tagttggagg gaagaattgt tcttctcttt tttaggttat
     9421 aagattctgg tctgacaaaa tcgttagact tttttcattt tttatgagaa acgtgctaac
     9481 tgctagaaat tatggtagaa taaagtatta agtaatcgtg gaaaaaggat atctatgcga
     9541 aaagaaattg cacctgaatt atacaactat aacaagtttc ctggtccgga gttccattta
     9601 cacggggaca aggtcgaaac ggaagggata gctttttcct tggttgaaaa tatcaaggat
     9661 gcctttgatg tgacgacttt taatcagcgt ttttcagaag tcttaaccaa gtttgattat
     9721 atcgtggggg actggagcaa cgaacagctt cgcctacgag gtttttacaa ggatgaccga
     9781 acagaagaaa aacttgaaaa aatcagtcgt ttacaagact accttttaga gtattgtagt
     9841 tatggttgtg cctattttgt cttagaaaat gaagccccta agcgagcatc atttgacaag
     9901 aaaatgcgta agacggaaga agaaacacct tctagaaaag gaaagaaacc gactcaaact
     9961 aaacgaaagt cgaatgcaga taagaaaaat agacgtcgtc agaaagacca gcattctcag
    10021 aaagaggaca aggaacaacg tcattttgtc attcgtcaga agtgagtaga gaataaggag
    10081 aagaaatgaa accctcaatt catagtttgg tacatcaaac catgcaggaa tgggtattgg
    10141 agcagggaga aaagaaattc cgtgcagatc aaatctggga atggctctac cgtaaacgtg
    10201 tgcagtcatt tgaagaaatg accaaccttt ccaaggattt gattgctaag ctcaatgacc
    10261 agtttgtggt caatcccttg aaacaacgta ttgtgcaaga gtctgctgat ggtacagtca
    10321 aatatctctt tgaattgcct gacggtatgt taattgagac tgtactcatg cgtcaacact
    10381 atggtttatc tgtctgtgtg accactcagg tcggctgtaa tatcggttgt accttctgtg
    10441 cctctggttt gattaagaag cagcgtgacc tcaataacgg tgaaatcgta gcgcaaatca
    10501 tgctggttca gaaatacttt gctgatgaag gggttcaggt caatcttgcc gtgtctcttc
    10561 acgcacccaa caatgaactt cgttcaagta tcatgaagat taaccgtgcc tttccgattg
    10621 aaaaactctt tgctgctatt gaatactaca ttgagacaac aaaccgtcgt gtaacctttg
    10681 aatatatcat gcttaatgaa gtcaacgacg gtgtagaaca agccttggaa ttggctgaat
    10741 tgctcaagaa catcaagaaa ttgtcttatg taaacttgat tccttataac ccagttagtg
    10801 agcatgacca atatagccgt agtcccaaag agcgcgtgtt ggctttctat gatacgctta
    10861 agaaaaaagg ggtcaactgt gtggttcgtc aagagcatgg tacagatatt gacgcagctt
    10921 gtggacaatt gcgctctaac acaatgaaac gtgaccgcca gaaggcagtc gcagcggtaa
    10981 atccttaatg atgaagaaga cttataatca tattttggtc tggggagtca ttttctatag
    11041 catttgcatt gtctgttttt gctttactcc tcaagaacaa tctaccgtgg gagtgggaac
    11101 tccaggtatt cagcatcttg gatgcctggt ttttcttttg actcctttca attctctctg
    11161 gaaactgggc gaagtgagtg acattggaca attatgttgg atttttttac aaaatgtcct
    11221 caatgtcttc ttgttttttc ctctgatttt ccaactcctt tatctatttc caaatttgcg
    11281 gaaaacaaaa aaggtccttc tttttagttt tcttgtgagt cttggaatcg agtgtacgca
    11341 attaatcttg gactttttct ttgatttcaa tcgcgtcttt gagattgatg atttgtggac
    11401 caatactttg ggtggctatc tggcttggct cctttataaa cgattacata aaaacaagat
    11461 aaggaattaa aatgagtatt ttagaagtta aaaatctgag tcacggtttt ggtgaccgtg
    11521 caatttttga agatgtgtcc ttccgtctcc tcaagggaga acatatcggc ctggtcggtg
    11581 ccaatggtga aggaaaatca acctttatga gtatcgtgac tggtaaaatg ctgccagatg
    11641 aaggaaaggt tgagtggtcc aaatatgtga cggctggtta cttggatcag cactctgtcc
    11701 ttgctgaaag acagtcggtg cgtgatgttc tccgtacggc ttttgatgag cttttcaaag
    11761 ctgaagctcg tatcaatgac ctctatatga aaatggctga agacggcgcg gatgttgatg
    11821 ctctcatgga agaagtagga gaacttcaag accgtctgga gagtcgtgat ttctatacct
    11881 tggatgctaa gattgacgaa gtagcgcgtg ctcttggtgt tatggacttt ggcatggata
    11941 cggatgtaac ttctttgtca ggtgggcaaa gaaccaaggt gcttttggca aaacttctcc
    12001 ttgaaaagcc tgatatcttg ctgttggacg agccgaccaa ctacttggat gctgagcata
    12061 ttgattggct caagcgctat ctccaaaact atgagaatgc ctttgttctc atttcgcacg
    12121 atattccatt cctcaatgac gttattaata ttgtctatca tgtggaaaat caacagctga
    12181 cgcgttactc tggtgactac taccagttcc aagaagttta tgctatgaag aaatctcagc
    12241 tagaggcagc ctacgaacgc cagcagaaag agattgcaga cctcaaggac tttgtggctc
    12301 gtaataaagc ccgtgttgca actcgtaata tggctatgtc tcgtcaaaag aaattggata
    12361 agatggatat tatcgaactc caaagtgaga aaccaaaacc atcctttgat ttcaaaccag
    12421 ctcgtacacc agggcgcttt atcttccaag ccaagaactt gcaaattggt tacgaccgtc
    12481 ctcttactaa gcctttaaat cttaccttcg aacgcaatca aaaggttgcg attattggtg
    12541 ctaatggtat tggaaaaaca actctcttga agagtctctt gggcattatc tcgccaatcg
    12601 ctggggaagt ggagcgtgga gattatttag aacttggtta ttttgagcag gaagtagaag
    12661 gtggtaatcg ccaaactcct cttgaagctg tctggaatgc ctttcctgcc cttaatcaag
    12721 cagaagtccg tgcagccctt gcccgttgtg gtttgacaac caaacatatt gaaagccaga
    12781 ttcaagtatt atcaggggga gagcaagcca aggttcgttt ctgtctcttg atgaatcgtg
    12841 aaaacaacgt tttagtgctg gacgagccga ccaaccattt ggatgtggat gcaaaggatg
    12901 agctcaaacg cgctctcaaa gaatacaggg gatctatcct tatggtctgc cacgagccag
    12961 acttttatga aggttggata gaccaaatat gggattttaa taatttaact taagaatgag
    13021 agtaaaagaa atacggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
    13081 aggacaaaat tcgtcctttc ttttttgatg ttcagagcga taaaaatcct ttttttgaag
    13141 ttttcaaagt tccgaaatcc aaaggcgttt cgtttgataa gtttgatgag attattggtc
    13201 gcttccaatt ttgcgttgga ataaggtaat tgaagagcgt tgacgatttt ctctttgttc
    13261 tttagaaagg ttttaaagac agtctgaaaa ataggatgaa cctgcttcag attgtcctca
    13321 atgagtccga aaaatttctc tggttcctta ttctgaaagt gaaacagcaa gagttgatag
    13381 agctgatagt gatgtttcaa gtcttgtgaa tagctcaaaa gcttgtttaa aatctcttta
    13441 ttggttaagt gcatacgaaa agtaggacga taaaatcg
//
LOCUS       DAVMJI010000044        12775 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.045, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000044 DAVMJI010000000
VERSION     DAVMJI010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12775
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.045"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(402..2129)
                     /gene="ezrA"
                     /locus_tag="VYR58_001813"
     CDS             complement(402..2129)
                     /gene="ezrA"
                     /locus_tag="VYR58_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV3622914.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIDEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2211..4157)
                     /gene="gyrB"
                     /locus_tag="VYR58_001814"
     CDS             complement(2211..4157)
                     /gene="gyrB"
                     /locus_tag="VYR58_001814"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV3622915.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4172..4735)
                     /locus_tag="VYR58_001815"
     CDS             complement(4172..4735)
                     /locus_tag="VYR58_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV3622916.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4820..5374)
                     /locus_tag="VYR58_001816"
     CDS             complement(4820..5374)
                     /locus_tag="VYR58_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV3622917.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5385..6608)
                     /locus_tag="VYR58_001817"
     CDS             complement(5385..6608)
                     /locus_tag="VYR58_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV3622918.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6645..9095)
                     /locus_tag="VYR58_001818"
     CDS             complement(6645..9095)
                     /locus_tag="VYR58_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV3622919.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPFSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9295..10224)
                     /locus_tag="VYR58_001819"
     CDS             complement(9295..10224)
                     /locus_tag="VYR58_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV3622920.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10364..10651
                     /locus_tag="VYR58_001820"
     CDS             10364..10651
                     /locus_tag="VYR58_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV3622921.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10685..12019)
                     /gene="ciaH"
                     /locus_tag="VYR58_001821"
     CDS             complement(10685..12019)
                     /gene="ciaH"
                     /locus_tag="VYR58_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV3622922.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12009..12683)
                     /gene="ciaR"
                     /locus_tag="VYR58_001822"
     CDS             complement(12009..12683)
                     /gene="ciaR"
                     /locus_tag="VYR58_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV3622923.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
BASE COUNT         3880 a         2730 c         2274 g         3891 t
ORIGIN      
        1 ctaaagttgt acaagaaaag tgcaaataag aaatctccag attaggaact atccgtgagt
       61 tctctagtct ggagattttt caatagactt cgttattgga cggttaccaa gttactcaaa
      121 gtacagattt gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca
      181 aaaagcaaac taagaagcta gcctcaggct gtacttgagt acggtaaggc gacgctgacg
      241 tgatttgaag agattttcga agagtataaa acactgtttt gaggtggtgg ataaatcggc
      301 tgggtaaaaa ctcaatctca ggagaaaatg aagtaaatct ccccacaact atagaaaaag
      361 atttgattct gctcctcaca caataaaatc tttttctttt attaaaaacg aatcgtttca
      421 cgtgttttct catatgaggt aacaaagcga ttggttacac caggctctgc cacttccaat
      481 gcttgagaaa tcttgtcaaa tgaagcgtga taatcaaatt ctttttcaaa aatatctaaa
      541 gcttcgttaa atgcttcttg aatgcgttca tcaaatgagc gatagcggtt agaatattgc
      601 aagagttgct ctgtcaaagt tgcatattgt acaatattat aagtttccgt ttctaaagct
      661 tccatatcat tcgttgcaat ttcaagaact cgggtaacag attcaatgtt aatcattttt
      721 tgttctaact caaccattaa atcctcggta ttattgcttg ccgtaaagaa taacttcaag
      781 aaagtttgtg gaatacctgg cagattgcgt ttttccatgt atcgcttgat agtatggaga
      841 cgattgacat aaacattggc cttttgacgt gcattaatat catctttctc aatttgtgtc
      901 aggcgctcac taactgaaat ttgctcatct tcaatatctt ttagttgagt ttgtaaatcc
      961 tcaagatttt cttcaagaac tgaataagct tgggttggtt cttcttgatt tgaagttacc
     1021 tcaacaatag ctgcctcaaa actctctaat tctgtctgaa tacgacgaac atggcttgca
     1081 gctgtctcag gaagtaaata ggtcttgttc aaacgtgcaa tatcttctcc caataaagta
     1141 ttattctctt tcatatgttg aaggtaagtt ggaagagttg caagtagatt ttccactact
     1201 ttctgagcag caatttctcg agtaaaaata tcatacaagg cattgatttc ctcttgtgcc
     1261 tgtccattct catattcggc attatccaat tccaactgac gaatattctc ttggtttttc
     1321 ttgaatgctt cataaagcaa gtggaaacgc gcttcaatat ccgtttcaac aaaatgataa
     1381 ttagcatcaa ttagtttacg ataaccggat tccaaatcct gtaattgatc tggcaattct
     1441 gtagaaagcg tcgtaaccaa ggctggaaca cgatccacaa tatgacttaa ggccaaaatg
     1501 tgattttctg tattatccaa aatcactgcg gcttccacag ggtcacccga tgaattcaag
     1561 gttacaaatt gtgaaaattc agattggata ttttctaatt gtttttcaat ttcatccaag
     1621 gcttgaccat actgttctga attttcagca actctatgct gaagttcctc aaataaatcc
     1681 aaagcatgaa gaacacgacc actattttta gattcttgct tctctaagtc tgccaaagca
     1741 ttgcgaattg ccgcaatatc ttcgtcaatc aaagtaattt gactctcaat ttggtcaatt
     1801 tgatgactgg ccttgagaaa acgaaatgaa tggttatagc cttctgcttc aaagagatta
     1861 ttttcaatat cggcaaaaga gttgagagat aaatcgaccc atttttgatt ccattcacgg
     1921 aaagccactt gactttgtcc aatcaagtgc atatttttta cagcttctac ttcatcattt
     1981 actggaagat tgtatagttc ttcttttctt tcttctagcg cctctaatct cccctcgttt
     2041 cgcttacgta gaaagattgc cactacataa gccagaacta aaatgactgc aattgcaacc
     2101 attaaataaa ttagttgtcc attagacata tcaaactcct tttttacttg aaacaatcgt
     2161 aacgattata tcatattttt tagaccaagg gaactacttc tccctatttt ttagacatca
     2221 agtgtactat agacagcatt ttcttcgata aactcacgac gaggctctac tcgatccccc
     2281 atcaacatat caaagatttt atctgcttct gcagcatcat ctacagaaac tctagccatc
     2341 aagcgatgtt cgggatccat ggttgtttcc cacagctgat gatcgtccat ttcacctagc
     2401 cccttataac gctgaatagt cggtttggta cgaccttcac tataacgggc taaagcttct
     2461 tggagtttga tttcttgatc tgcacccggc tggatatatt ctttaatctc gcttccaacc
     2521 ttgacaccat agattggtgg ttgggcaata taaacataac cagcttctag gattggtttc
     2581 atataacgat aaatcaaggt taaaagaagg gtacgaatgt gggctccatc gacatcggca
     2641 tcggtcatca aaacgagttt ttggtaacgg gctttcgaaa catcaaattc tgcgccaaat
     2701 cctgttccca tggctgtgaa aagactacga atttcttcgt tagctagaat cttatccata
     2761 cttgcttttt caacgttcaa aatcttaccg cgaattggaa ggatagcctg aaactcacgg
     2821 ttacgaccag atttggctga tccaccagct gagtctcctt cgacgatgaa gagttctgtt
     2881 tcagcagggt tattagaaga acagtctgct agtttccctg gaaggttgga aatttccaaa
     2941 ccagattttt tacgtgtgac ttcacgcgca cgcttggcag ccacacgagc cttggcagct
     3001 aaaatccctt tttccacgat acgtttggca atctgtggat tttccatgag gaaatcggag
     3061 aaggcttcac tgaagaggcg attggtaatc ttgaccactt cgctatttcc caatttggtc
     3121 ttggtttgtc cttcaaactg tggatttggg tgtttaactg agataactgc agttaatcct
     3181 tcgcgaacat cttcccctgt taaattatct tcattgtctt tcagtaactt attcttacga
     3241 gcataatcat tgataacacg agtcagtgcc gtacggaaac cttgttcatg cgttccacct
     3301 tcatgggtat gaatattatt ggcgaaactc atgacatttt catggtaacc tgttgtgtac
     3361 tgcatggcta cctcaactgt gatatcatcc atctcaccgt ctgtatagat tggtgtatca
     3421 aagattacat ccttgttctc gttgatatat tcaacgtaac tagcaatccc accttcataa
     3481 tgataatgct tggtttgttc caaaccttgg cgcttatctg taattgaaat ttgaagaccg
     3541 cgatttagaa aggccaactc ttgaatccgt ttatttaatt tatcaaaatc aaagattgtt
     3601 gtttcagtga aaatttctgg gtccggtgtg aagtgaaccg ttgttccagt tctatctgta
     3661 tccccaacca cctcaaggtc tgcaacaaca tgaccacgac ggtattcttg gtaatgaatc
     3721 ttaccgtttt tatggacatg aacgtctaat tgagtggaaa gggcattaac tactgacgac
     3781 cccaccccgt gaagaccacc tgaaaccttg tatccaccac cgccgaactt tcctccagca
     3841 tgaaggactg taaagacggt ctcaacagca ggacggcctg ttttttcctg aatatcgact
     3901 gggataccac gcccatcatc cacaacagta atcgaatcat ctggctcaat aaaaacttga
     3961 atatggctgg caaatcctgc caaggcctcg tcaattgagt tatcaacaat ttcccagact
     4021 agatggtgaa gaccttcttt tgaggttgat ccaatgtaca tccctggacg catacgaaca
     4081 gcctctaagc cctctaaaac ttgaatttga ctggcatcat aatcctgtgc ctgcagattt
     4141 ttgatttctt ctgtcatctt attccttttt cttatatgtc taatacttgt cttaaattca
     4201 cgatactggt aaacaagtgg gtatcaagtc ctgcagcttg acctgcttcg atatcaatcg
     4261 gccgatcacc aatgacaaga ccagagctaa tctgatactt ttctcttaaa taaagcatgg
     4321 attcgggatt tggctttctc ttaaagcctg agctagaagt caccacttct gtaaaataag
     4381 ctgctataga ggttttttct aaaatttcca aaacctgatc atttcgatga gagaccaaaa
     4441 aatgacggcc accttgattt aaaatgtctt ccaataggtc agaaactcct tcaaataaaa
     4501 tcgggtgttc aagctctctg gcttcatttt ccttgtactt ttctaaaaaa ttctctaaat
     4561 tgggagcgaa tgtctcaatc gcaaaaggag tagaaacctt taaagcttga tagacactgt
     4621 catggtcttg tgtgatacca tacagtgcca atgtttcaac aaatgcagct gttgaagttt
     4681 cataattatc cagtaaagtt ccacctaaat cccagatgta atcgtgatat ttcataccct
     4741 tcattatagc atttttttat gaaaaaagcg atgatttccc tgagttttcc acataaaaaa
     4801 cgagagaata actcccgttt tactgatttt taccaaagac atctcgatag agcattcctg
     4861 ttcgtaaact ctctgcgtcc cctcctagtt gctccaccaa ctcgtaggca aaggcaaggg
     4921 ctgttgaagg accccgactg gttgtcaact gaccatctac cactactgtt tccttgacgt
     4981 agtgaccatc aaggatttgc tcttgaacgc cgtcataaca agtgtatcgc ttatttttca
     5041 atatctctgc ttgattgagg gcaattggtg ccgcacaaat ggctgctagt ttcttccctt
     5101 cttgctcgaa gctttgcaat tcttgaatca aggtctgatt atcacgtaaa tgtgcagaac
     5161 caggcatacc tccaggaaga acaatcatat catagtctga taaatctcca tcaaagacat
     5221 gatctgctct tacttggatt gcatgcgaac ccgttacttg ctcttcaaaa ccaaccatat
     5281 cacatgtgat attggctcga cgcaagacat ctacaactgt caaggcttca atttcttcaa
     5341 agccctgagc taacataact gctactttta ccatgatttt ctccttattt aatttgtttt
     5401 aatacaacct ttttccgttt gaatgggact tttccgctct tttcttcagc taaattagtc
     5461 tggtaactca tcgataaaag caaaccaaca ccaatcaaat tactgataat agctgatccc
     5521 ccttgcgaaa tgaaaggcaa gggaatcccc gtcaaaggaa gtagtccagt cacagcaccg
     5581 atattctcaa agatgtggaa gagcaacatc ataatcaaac ctgtggaaat ataagtgtag
     5641 aactggttat ttgatttaag agtaatcttc aacatacggt aaatcaacat gagatagagg
     5701 gcaataacca ggacagagcc aataaagcca aaatcttctg caataaccgt aaaaatcata
     5761 tctgactctc gaactgggat aagcagattc gaagcattaa atccctgacc aaataagcca
     5821 ccactcccaa tggcaatctg cccttgagcc tgctggtaag tcgttgtttg ggcaaactca
     5881 aagggattga gccaagccaa aatccgatta atttggtagg tcggcattcc aatctggtga
     5941 agaaaagctc gtccgtcctt gctaataaag atagctaaga aaccagcaac tcctgttaca
     6001 gcagtcacaa atactgggat aataattttc caagaaaccc ctgataataa aacgattcct
     6061 gagaaaatgg ctacaaaaac caaagccgtc cccaagtcac tttgaagtgc taaaagaact
     6121 aggactggaa tggtaaagag aatcatccag aaaattaaca aaaagtccag cggaaccgtg
     6181 cgtctccatt ccttatgttt ctttgtaaat tggacaatga cacgagccaa catgaggata
     6241 taggatatct tcataaattc tgacggttga aatagggtaa ttccatttat tgatacccag
     6301 tttttggcac ccgttgatgc aactaagctt ggattataaa atacaatcgg caagatcata
     6361 agtcccaagc ctaaaatata tagaaagggg gtcaccttcc aaagaaattc tgtattaaag
     6421 agcatgacca caaaaccaat cacaagcccc aaggcaatcc aggcgacctg ctgccctaaa
     6481 atgggcagaa tattattggg ataatcatga ctaacggcta tatagatagc caccacaccg
     6541 atgaccagta gaaaaaatac tggcaagagc aaactataat cgactctaga gtcgagagaa
     6601 cgtttcatat gtactaacct tatactttca tacaatacta tttatcaaag ttcattaaaa
     6661 aatctatcaa tagcctcgtc aacttcggat cgagagatgg ttttaacagt cgcttcttct
     6721 gctagagatg ctactatttg tttgccgtat cgttttccga cgattctcct atccaaaata
     6781 agagttaagg aacgttggta ttcacgtctc atacttcttc ccaaagcctg ttttaaacga
     6841 ataatggcca ttggcaattg ataatcataa aaggcatttt tcccttcttg attcagttct
     6901 tgattaatct ttttcgtcaa gggttcttga ggattttgga aaggaagcct cggtacaact
     6961 tgaatcacag aaggatggct tgaaaaatca actccctccc agaaacttgc tgcaccaagc
     7021 aagatttgtt gttcaccttt ttcaaagcgt ttctttagct gatgaacatc cccattttta
     7081 tactgggcca agtggctaac tgtaagtaaa tccgatactg ctagaagcat gtctttagcg
     7141 gtaaagagaa ccaaaatcgg ttgctggaaa gcttgaattt ccactagtaa agcagctacc
     7201 tctctggcat agacttctaa ggaggtttct gttaccagag ggaaatcttt gaccataacc
     7261 acttcttgtt cctgttttcc ccgagattca atcttgacaa atttggcttc aggatagcct
     7321 aaaaggtctg ccaaagaaac cctctgacta atctcaagag tagccgatac tcccaagact
     7381 tggcaactct caggaagtaa agaggacaga agagtacggc ctgattttgt agaagaaatc
     7441 tgaattttct tttgactcgt ttcagttact tcaagccagt aatcaccttc agctgtaaaa
     7501 tagcgaacca gctcatcaaa gccttccact tctaattctg aaaaatactg atggagattg
     7561 tccagagaat ctaagatatt tttcctagat ttaccagact gaaattgttc tatcaagtag
     7621 agacactcaa agcgaatact ttctagtatc cgttgttgaa ccctgttttc ttctcctact
     7681 aaagccttat caattaaatc gataatagat tgtatatcgt aggtctcttg aagcagattt
     7741 tctagagcta acaaaatctt ttggacttca tcaataatca gtaaacggtc actgacaaat
     7801 tcaggattat cttcaagtct ggtcacgaga taggcatgat tagtcactaa aagcttgcaa
     7861 gtctctgccc tttcttgact acgtttccaa aaatcttccg tcacaaataa gctctgggat
     7921 gataaattcc catcatgacg aaggtctgct agaaaatgtt ggtaacggta gagttgcccg
     7981 atttcatcca aatctcctgt ctctgtctca gtaagccaga ccaagacttg cattttaaag
     8041 cgtctaaata agcgattttc atcattttcc tgcaaggaat gataaaaggc atccaacttc
     8101 agataatttt gtggtccctt taagctatga atatctgtat ggaacacttc cttgagacgt
     8161 ttaccttctt cttccatgat ttgattttga agaatctttg tcggaacact aagaacaatt
     8221 tgtcgctctt tggattgaga taaagcgggt aagagatagc cataggtttt cccaatccct
     8281 gtcggcgctt gaatcagaga gaaaggttca tctttcaata gcaagccaac ctctttagca
     8341 aaactttctt gttcctccct cacttcaagg ttcaacagag aaatattttt agaaaagtct
     8401 tgagatagtt ttcgtagctc cagagaagct gccgttttct taaaatacag accttgaact
     8461 tggaccaagt ctggagaact caggatagat tggttgcgat aagtttcctc aataaccagg
     8521 taagactcat ataggagagc gtcagccatt tccagcaagc gttccaagag acctttagga
     8581 agctgggtca tcttttcccg taaaaaaaga agtaattctg ctgtagcttg ggcatctgaa
     8641 agggctgtgt gtgcgtgttt aagaggaatt cctaattctc gacacaaaat cggcaagcta
     8701 tatttttcca gttcagggaa aaagacctgg gccaattcga ccgtatcaac acgagggttt
     8761 cttagctcat agccttcaaa aaataaattt tccgccaaga gattagcatc aaactgaaca
     8821 ttatgggcta caaaaatccc atcctccacc aagtcaaaga tttttctggc aacttgcgaa
     8881 aaatcaggtg cttgcgccag acgttggtct gtcaatcctg tcagttcttt gatatgagca
     8941 tccaagggtt catgtggatt gacatccgtc gtatagtgat cgacgatttc tccatcctca
     9001 atcacgacaa ttcccacttg gataatttta gccttactac ctgtgctagt tgcctctaaa
     9061 tccaccacaa catagcgatt accaatcgtt ttcattataa aaaattatac caaaaaaagg
     9121 gccatttggc acctgcaaac ataggataat tttcaaactc aagaacacta cttttcttag
     9181 aaatcccatc gaatagagca ttctagcctg ctgatttttt taaaatagtg aagaaatacg
     9241 aaaaattgag agaagaaatg ttttcatctt ccttctctca acgaatcatg tattttattt
     9301 aaccatgtca ggatcgtagt cataaaatcc tgtatcaagg aaacggtttt tagggtgaag
     9361 tttacgaact tcttcatcca gcaagaaggc ttggtcatgg ctaaagttgc cctcttgaat
     9421 caagctacgc gcttggataa agagttttgc aatctcaaca aagttctgac caggagtgta
     9481 gagcccttct agtttccagc gagtaaagcc atgctccacc aattctgtta atttgatcat
     9541 caaatcaagg tcattgttgg caaagatatg ggtcccatga ttatcttcaa aaatggaata
     9601 gtggctctct ggatcacttg gctcagccaa gaagaggtca cgtttatgcg tcttttcatc
     9661 atcgatatgt gtaaagttat agtagttttg caagagtgga cgtttagaat gatggatgac
     9721 gctagcaccg taaaccaaaa cttcagcagg aatttccaaa atctctggca ttttgaaaag
     9781 ttcagctgat ggaatttcac gcgccaaaac agcctcagat gcgccagcct tttgtcccca
     9841 gaagttaatc tgacgactgc tagttaccat ggttgaagca tcgtagatgg tcttaaatga
     9901 ataaccatcg cggttaacta cgtaaaagac gcctgcatcc ccaatcgtaa tatagtctgt
     9961 cttgatttct tccaagaagt ctaagaaagg cttgatacgg tccatcatat cttggtgcat
    10021 gagagcattg accgcaacga tcaattcctt accagcatca tgaaccaact tagcgatttc
    10081 acgtaattgg tcataactaa aggtcgttgg cagacgaagg ccaaaatctt tctcaccgac
    10141 atagatacgg tctacgccag cttcgagtag ttgttcaact tgttcaatac tttcagcagt
    10201 tgctgtaatg acaatctttt ccataagaaa aattatacca catttctcca aaatcagcca
    10261 tgctttgaaa atgaaaaggg actttattct ttttgtaacc tttctgtaat aattctctgc
    10321 cgaaaaaatg ataaaatagg tatgtactgt taaggagaga atcatgcccg taagaaaatt
    10381 acaatcctat gaggtagact atcaagaaga attaaaccag cagcttcctc attaccaagc
    10441 ttatacacct gaagcgcaat ctgatgccaa tctcaaggaa atcctatttt ttattaatat
    10501 cgctgttttt tgtatctgta ttgctatctt tagttttatc tttttagcat taaaattatc
    10561 aactgctctt gcctttgccg cagcaatcgg attcagctta cttgttttaa aagttcaacg
    10621 gtctattatc aaacgaaaac gtagaagata aatccaaaat atcgccccaa ttggagcgat
    10681 atttttattt tttcttttta gatggtgtct gaatggcaat cttcacttca aagattgttc
    10741 ccttgggttt attatctttg acagtaacag ttccttttag agcatctaca atttgcttgg
    10801 ctagggataa tcctaaacca aaaccacctt tttgccgggt tctagctttg tctactcgat
    10861 aaaaacggtc aaaaattttc tttttatctt ctgtcgaaat accgattcca ttatcagaaa
    10921 caagtaaata aagattgcga tcggtcgccg agataagaaa atcaatttca ccatcctcct
    10981 cagtatactt gacggcatta tcgaaaagaa tggtcatcag ttgtttcaga agaagctgat
    11041 ctgtgacaat tgttcgatgg atacgatttt caaaacggaa gacacgatta ttttccgaag
    11101 caatcatctc atagtttgtg aaagttgtat taaaaaagct agttggaact tctgcaagct
    11161 ccggcttaat cccatcatct ctccgagcta agttcagcaa gcttgtcgtt aaaaaacgca
    11221 tatttcggac ttcttccaaa ctcgatgcaa tgctttcgct cacatccata atggtagctt
    11281 ctggcttacg aaaaagggtc tctaagcgat tttgcaaaac tgcgagtgga gttcgtaact
    11341 catgactggc attttccaca aaagactgtt gcttctgcat actctcaagc aggggcctaa
    11401 cactgaccct agctagatag agactggcaa gtaaagacaa aatccagaaa ctagccatca
    11461 cgaccacaat caattgctca tgcttttgac tagcctgctc caactgactg gtattaatca
    11521 agacagcagc atacttgata ttggttgaaa ccgaactaat attggtctcc atcaaaatca
    11581 cacgatagat ttcttcctgc ccatagctat taaaaacctg aatctggtag atatgtccta
    11641 gttctttctt ttctaactta atcttatcca agcccaaaaa tcgatttcca gaaagaagtt
    11701 gagtaaagtc tttatcaaag agaatgactt ccgtattgga actgacatta ggttttattt
    11761 ctactttact agcgtccgcc ctagcatttt ctaaatcttt aatctcttct gttgccctat
    11821 ttatagccag ctgaataact gcttgaggat tttcactcag tccatgaagc ttatcgtcca
    11881 ccgaagtata aagactcgaa tgcatgactt gtaaaataat cagagtcatt gtagaaaaaa
    11941 tcagggtgaa gacaccgaag ttgcggataa aataactaaa gtcatccgca taccatgttt
    12001 ttttaagttt actgaacatc ttttaaaaga tacccaacac tacgcaaggt ttgcaaattc
    12061 tctgcaaaag tggttccctt taatttctta cggacttttg aaacatagac ttcgacaacc
    12121 gaaatcgttg tatcactatc aaatccccat agacggtcaa aaatctgcgt cttaggcaaa
    12181 atcacatttt gattttgaag gaaataaact agtaaatcga actctttccc cagcaattcg
    12241 acaggagtat cttcaacttt aacggtattg gttgataaat taaccacgat attcccataa
    12301 gtcaaggtgt tttcattaaa cttccctgaa cgtttgagaa gggcctgaat tcgcatttta
    12361 agttcttcta ggtagaaagg tttggtcaga taatcatccg ctcccagttc aaatccatgt
    12421 cccttgtcat ccaaactttc cttggcagtc ataatcagaa ctggtgtcgt aattcccttt
    12481 tcacgcaatt cttttaagac ttggaaacca tttttttctg gcaacatcaa atccagcaaa
    12541 atcaagtcat agacaccact ctcagcttcg tagagacctt cttctccatc aaatacctgc
    12601 ataacatccg caaaatcgtc taaaaagtca aatactgaat ttgacagacc taggtcatcc
    12661 tcaaccaata agatttttat catgagaaac tcctccttat taaaactatt ataccaaatt
    12721 tgccttaaaa aaaactcaac tctctgcatt ttacatgaga tagctgagtt ttctt
//
LOCUS       DAVMJI010000045        11602 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.046, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000045 DAVMJI010000000
VERSION     DAVMJI010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.046"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            72..935
                     /locus_tag="VYR58_001823"
     CDS             72..935
                     /locus_tag="VYR58_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3622924.1"
                     /translation="MSTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIQAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELGTV"
     gene            1318..1938
                     /locus_tag="VYR58_001824"
     CDS             1318..1938
                     /locus_tag="VYR58_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622925.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2024..2467
                     /gene="tsaE"
                     /locus_tag="VYR58_001825"
     CDS             2024..2467
                     /gene="tsaE"
                     /locus_tag="VYR58_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV3622926.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2457..2975
                     /locus_tag="VYR58_001826"
     CDS             2457..2975
                     /locus_tag="VYR58_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622927.1"
                     /translation="MEYELLIREAEPKDAAELVTFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            2983..3999
                     /locus_tag="VYR58_001827"
     CDS             2983..3999
                     /locus_tag="VYR58_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV3622928.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4084..5340
                     /locus_tag="VYR58_001828"
     CDS             4084..5340
                     /locus_tag="VYR58_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV3622929.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5395..6561
                     /gene="recA"
                     /locus_tag="VYR58_001829"
     CDS             5395..6561
                     /gene="recA"
                     /locus_tag="VYR58_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV3622930.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            6868..8238
                     /locus_tag="VYR58_001830"
     CDS             6868..8238
                     /locus_tag="VYR58_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV3622931.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8614..9570
                     /gene="lytA"
                     /locus_tag="VYR58_001831"
     CDS             8614..9570
                     /gene="lytA"
                     /locus_tag="VYR58_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV3622932.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            9942..10103
                     /locus_tag="VYR58_001832"
     CDS             9942..10103
                     /locus_tag="VYR58_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3622933.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            10090..10296
                     /locus_tag="VYR58_001833"
     CDS             10090..10296
                     /locus_tag="VYR58_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622934.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISRVCYKGTQFSLIAVNSDMSLGR"
     gene            10342..10701
                     /locus_tag="VYR58_001834"
     CDS             10342..10701
                     /locus_tag="VYR58_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622935.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKETVLG"
     gene            10829..11254
                     /locus_tag="VYR58_001835"
     CDS             10829..11254
                     /locus_tag="VYR58_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622936.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
BASE COUNT         3649 a         1879 c         2553 g         3521 t
ORIGIN      
        1 tctttaactt gctattttga actaaaaatt ttataatgca attaagcaaa taggaaggtt
       61 tattatcttt aatgagtaca ctcgcagaga aattcagatt gaaaagaaaa gagttgagac
      121 tctcccaaca aactcttgca gaaggaattt gtgaacaaag ccagattagt aaaattgaga
      181 gagggcattt cattccctcc gcagaccttt tgttcaaact ctctcaacga cttgaagtac
      241 cattagatta tttttttaat gaacaaattg aaattaaatc taacctctct aatttcaagc
      301 aattgtctgc tcgactatta gacgatagaa attatgacga tttggaatat atttatagaa
      361 tagagattga acgaagtact tttctaacac tagaagaccg aacttacctt gaatggattc
      421 aagctattat tgacttctat caatatgaca gtaagtgtga ggcaatttct tcattggaaa
      481 atatattatt aaaagtctct tcaaatactc tgatttattt aaaggcgttg aatactctat
      541 ctaatttcta ttccttagtg ggtcgtgaac aagaatatga ggcaaactac tctcatttaa
      601 tagagttgta tcagacaaaa aatttggacc atcaagagtt tttatttggc tacatcagag
      661 ttcgttacaa ctacgctcac tacctagtat caaaggaaaa atataatgaa gccatccaag
      721 aagctcttga aacgattgaa ctctgtaaac aaagacagac aagctaccaa ttggctcctc
      781 tacttattct tgtaggaaat gctggagcca aatttctaga cagagaacaa gtcaaaaatt
      841 attatataga agcaagagag ttatgtaaga tttataacaa tcctttaatg ttgatgaaga
      901 tagaaaatta tttgaaggaa ctaggtactg tttagttaat cttgacatta taatttttct
      961 gaaacgttaa ataacctgta aggctgatag ttagattaat actatcagcc ttataattat
     1021 gtgactctga gtccgtctcg ctccgtgagg tgcgagacaa aacaaccacc cgtttgacgg
     1081 attttcatga tttcaaattt atattcttcg aaaatctctt caaatcacgt cagctctatc
     1141 tgcaatctca aaacactgtt ttgagcaacc tgtggctagc tacctagttt gatctttgat
     1201 tttcattgag tattagtctc tagtgtttgt ttagcgtctt aaagagacat ttgagaagat
     1261 tagaaacagt tctctctttt ctcctagtat aatgattggt aggaagggag agagaagatg
     1321 aaatcaatga gaatcttatt tttgttagct ttaattcaaa tcagtttgag tagctgtttc
     1381 ctatggaagg aatgcatctt gtcctttaaa caaagtacag cttttttcat cggaagcatg
     1441 gttttcgttt caggaatctg tgctggagta aattatcttt atacccgtaa gcaagaagtc
     1501 catagtgtcc tagccagtaa gaagtcggtg aagctttttt acagtatgtt actcttaatt
     1561 aatttgttag gagctgttct tgttttgtca gataacttgt tcatcaaaaa tacgctgcag
     1621 caagaattag ttgacttttt attgccatcc ttctttttcc tatttgggct agatttgctg
     1681 atttttttac ccttgaaaaa atacgtgcgc gattttcttg ctatgctaga cagaaaaaag
     1741 acagtgttgg tgactatttt agcaacactt cttttcttaa gaaatccaat gaccattgtc
     1801 tcacttctga tttatactgg actgggcttg ttttttgcag cctatcttgt cccaaattcg
     1861 gttaagaagg aagtttcctt ttatggtcat attttccgag atcttgtatt ggtcattgtt
     1921 acgctcattt tcttttagag aaagcctgtt ttttatggat gttatgatga taagtttagt
     1981 aggaaaatag acacaaaaga aaagtttttg gtataataag agtatgtaca caaaaaatga
     2041 agaagagttg caagccttag gggagcgttt gggccatcta ttagcaaaga atgatgtttt
     2101 aatcttaact ggagaactgg gtgcaggtaa aacgaccttt actaaaggac ttgcaaaagg
     2161 attacagatt tctcaaatga ttaaaagtcc cacctatact atcgtgagag agtatgaagg
     2221 tcgacttcca ctttatcacc tagatgttta tcgtattgaa ggagatgctg attctatcga
     2281 cttggatgag tttatctttg gtggcggcgt gactgttatt gagtggggaa atctcttagg
     2341 agatgccttg ccagatgctt atttagaatt ggaaattcta aaagaagcag atggacgccg
     2401 tttaaatttt caggcaaagg gtttgcgtgc tgagaaattg ttagaggagc ttcaatatgg
     2461 agtatgaatt gctcattagg gaagcagagc ccaaagatgc agctgaatta gtgacctttt
     2521 taaatcgtgt gagtttggag acagacttta ccagcctaga cggagatggt attctcttga
     2581 ctagtgagga gatggaaata ttcctcaaca agcaagctag ttcggacaat cagataacct
     2641 tacttgcatt cttaaatggc aaaattgctg gtattgtaaa tattacagct gatcagcgta
     2701 agagagtccg tcatattgga gatctcttca ttgtgattgg aaaaagatat tggaataatg
     2761 gcttgggaag tttgttgcta gaagaagcga tagagtgggc acaagcaagt ggcattctgc
     2821 gtcgtctcca actgactgtc caaactcgta atcaagcagc agtccatctt tatcaaaagc
     2881 atggctttgt cattgaaggt agccaagagc gtggggcata tatagaagaa gggaaattta
     2941 tcgatgttta cttgatgggt aaactgatag attagtagaa atatggttaa aaaaattatt
     3001 ggaatggtgc tagctttact ttctgtaact gtagtaggag taggtgtttt tgcttatact
     3061 atttatcaac aagggacaga aaccttagct aaaacctata aaaaaatcgg cgaagaaacc
     3121 aaggttattg aagcgactga acctctaacc attctgttaa tgggagtgga caccggaaat
     3181 gctgaacgaa ctgaaacttg ggtcggtaga agtgatagca tgatcttgat gacagtgaat
     3241 cctaaaacga aaaaaacaac aatgatgagt ttagagcggg atattctgac gcgcattgaa
     3301 tcagggaatg gtcaggctca tgaagcgaaa ctgaactcag catatgcaga tggtggagca
     3361 gagcttgcta tagaaaccat tcaaaaaatg atgaatatcc atattgatcg ctatgtgatg
     3421 gtcaatatga gagggttgca aaaactagtg gatgcagtag gaggtattac agtcaataat
     3481 atcctaggtt tcccaatttc tatcagtgac caagaagaat ttaatactat ttctatcggt
     3541 gttggggagc aacatattgg gggagaagaa gccctagtct atgcacgaat gcgttaccaa
     3601 gatcctgagg gggattatgg tcgtcaaaaa cgtcaacgtg aagttattca aaaagtcatg
     3661 gaaaaagctc tcagtttaaa tagcgttggt cattatcaag agattctaaa agctttgagt
     3721 gacaatatgc agaccaatat tgatttgtct gcaaaaagta tccctaactt gctaggctat
     3781 aaagattcat ttaaaaccat tgaaactcag cagttgcagg gtgaaggaga gatacttcaa
     3841 ggtgtttctt accagattgt ttcgagagca catatgttgg aaatgcaaaa tatactccga
     3901 cgttctttgg gacaagaaga agttactcag cttgaaacca atgcggtttt atttgaagat
     3961 ttatttggca gagcacctgt tggtgatgaa gataattaac ttttgataca aataaaaaaa
     4021 tcaatcgtag gaaaattcct gcgatttttt caaaaaaata cgaatagata ggtaggagga
     4081 aacatgaaag cagaaatcat tgctgttgga acagagattt tgacaggaca gattgtcaac
     4141 accaatgccc agtttttgtc ggaaaaacta gctgagattg gggtagatgt atattttcag
     4201 acggctgtag gagacaatga agttcgtctc ttgtctttgc ttgagattgc cagtcaacgt
     4261 agcagtctgg tgattttgac aggcggtttg gggccaactg aggacgacct aaccaaacaa
     4321 accctagcta aatttttagg gaaagcatta gtctttgatc ctcaggctca ggagaagttg
     4381 gatatctttt ttgccctgcg accagactat gcccgaacac caaataacga aagacaagct
     4441 caaattgtag aaggagcgat tccactgcca aacgaaacag gactggctgt tggaggaaaa
     4501 ttagaagtag acggagtgac ctatgtcgtc cttccaggtc cgccaagtga attgaaaccc
     4561 atggtcttaa accaacttct acccaagttg atgacaggga gcaagctgta ttcccgagtt
     4621 cttcgtttct ttgggattgg cgagagccag ttggttacga ttttggctga tttaattgat
     4681 aatcagatcg atcctacctt ggccccttat gccaagacag gagaagtcac tctacgtctg
     4741 tcaacaaagg ctagcagtca agaagaggcg aatcaagcgc tggatatctt ggaaaatcaa
     4801 atcttggact gccagacttt cgaaggaatt tctttacgag acttttgcta tggttatggg
     4861 gaagaaacta gtttagccag cattgtggta gaagaactga aaaggcaagg gaaaaccatc
     4921 gcggctgcag agagtttgac ggcaggtctt ttccaagcta ccgtggcgaa tttttctgga
     4981 gtttcaagta tatttgaggg tggttttgtg acctatagct tggaggaaaa atcaaggatg
     5041 ttggatattc ctgccaagaa tttggaagaa catggtgtgg tgtctgaatt tacagctcag
     5101 aagatggctg agcaggcacg aagcaagacc cagtctgatt ttggaattag tttgactgga
     5161 gtggcaggac cagatagcct agaaggacac ccagttggga cagtcttcat aggcttggcg
     5221 caagatcaag gaactgaggt tatcaaggtt aatattggag gcagaagccg agcagatgta
     5281 cgtcacattg cggttatgca tgcctttaac ctagttcgca aggctttatt aagtgactaa
     5341 cttttgatat aatagtagat aggtctgagg atcattagaa tgtaggagaa tagaatggcg
     5401 aaaaaaccaa aaaaattaga agaaatttca aaaaaatttg gggcagaacg tgaaaaggcc
     5461 ttgaatgacg ctcttaaatt gattgagaaa gactttggta aaggatcaat catgcgtttg
     5521 ggtgaacgtg cggagcaaaa ggtgcaagtg atgagctcag gttctttagc tcttgacatt
     5581 gcccttggct caggtggtta tcctaaggga cgtatcatcg aaatctatgg cccagagtca
     5641 tctggtaaga caacggttgc ccttcatgca gttgcacaag cgcaaaaaga aggtgggatt
     5701 gctgccttta tcgatgcgga acatgccctt gatccagctt atgctgcggc ccttggtgtc
     5761 aatattgacg aattgctctt gtctcaacca gactcaggag agcaaggtct tgagattgcg
     5821 ggaaaattga ttgactcagg tgcagttgat cttgtcgtag tcgactcagt tgctgccctt
     5881 gttcctcgtg cggaaattga tggagatatc ggagatagcc atgttggttt gcaggctcgt
     5941 atgatgagcc aggccatgcg taaacttggc gcctctatca ataaaaccaa aacaattgcc
     6001 atttttatca accaattgcg tgaaaaagtt ggagtgatgt ttggaaatcc agaaacaaca
     6061 ccgggcggac gtgctttgaa attctatgct tcagtccgct tggatgttcg tggtaataca
     6121 caaattaagg gaactggtga tcaaaaagaa accaatgtcg gtaaagaaac taagattaag
     6181 gttgtaaaaa ataaggtagc tccaccgttt aaggaagccg tagttgaaat tatgtacgga
     6241 gaaggaattt ctaagactgg tgagcttttg aagattgcaa gcgatttgga tattatcaaa
     6301 aaagcagggg cttggtattc ttacaaagat gaaaaaattg ggcaaggttc tgagaatgct
     6361 aagaaatact tggcagagca cccagaaatc tttgatgaaa ttgataagca agtccgttct
     6421 aaatttggct tgattgatgg agaagaagtt tcagaacaag atactgaaaa caaaaaagat
     6481 gagccaaaga aagaagaagc agtgaatgaa gaagttacgc ttgacttagg cgatgaactt
     6541 gaaatcgaaa ttgaagaata agctgttaaa gcagtggaga aatccgctac tttttcgatt
     6601 tttgattcaa gtttttagat tatatatagt agcttgaaat aagatatgaa caactttatt
     6661 aggaaagtca aattaatttc tagaaatgtt ttagcagcta cagcgtacta ttccaaactc
     6721 aaccaactat aatagatcga aactagaata gtacacatct acttctaaaa cattgttaaa
     6781 aatcgatttg actgtcctta tttcattccg ctatatataa gtttgctgtt tcttgtcgct
     6841 cctctggaaa gctgatataa tagctttatg aataaaaaac gaacagtgga cctgatacat
     6901 ggtccgattc ttccctcgct cttaagcttc acctttccaa tcttgctatc aaatattttt
     6961 caacagctct ataacactgc tgatgtcttg attgttggac gatttcttgg tcaagaatcc
     7021 ttggctgcag taggagcgac gacagcgatt tttgacctga ttgtaggttt tacacttggt
     7081 gttggcaatg gcatggggat tgtcattgct cgttattatg gggctcggaa tttcactaaa
     7141 atcaaggaag cagtagcagc cacctggatt ttaggtgctc ttttgagcat tctagttatg
     7201 ttgctgggct ttcttggctt gtatcctctc ttgcaatact tagatactcc tgcagaaatt
     7261 cttcctcaat cttatcaata tatttctatg attgtgacct gtgtaggtgt cagctttgct
     7321 tataatcttt ttgcaggctt gttgcggtct attggtgaca gtctagcagc cctgggattt
     7381 ctgattttct ctgccttggt taatgtggtt ctggatctct attttattac gcaattgcat
     7441 ctgggagttc aatccgcagg acttgctacc attatttcgc aaggtttatc agcggttctc
     7501 tgcttttatt atattcgtaa aagtgtgcca gaactcttgc cacagtttaa acatttcaaa
     7561 tgggacaaaa gcttgtacgc ggatctcttg gagcaaggtt tggctatggg cttgatgagt
     7621 tcaattgtat ctatcggtag tgtgatttta cagttttctg ttaatacatt tggtgcagtg
     7681 attattagtg cccagacggc agctcgacgc attatgacct ttgcccttct tcctatgacc
     7741 gctatttctg catcaatgac gacctttgct tctcagaatc taggagctaa gcgacctgac
     7801 cgcattgttc aaggtcttcg aatcggcagt cgtttaagta tatcctgggc agtttttgtt
     7861 tgtattttcc tcttttttgc cagtccagcc ttggtttcct tcttggctag ttcgacagat
     7921 ggttacttga tagaaaatgg aagtctctat ctgcaaatca gttcagcctt ttatcccatt
     7981 ttgagcctct tgttgattta tcgcaattgc ttgcagggct tggggcagaa gatccttcct
     8041 ctagtttcta gctttattga actaatcgga aaaatcgttt ttgtggtttt gattattcct
     8101 tgggcaggat ataagggtgt tatcctttgt gaacctctta tctgggttgc catgacagtt
     8161 caactgtact tctcactatt ccgtcatccc ttgataaaag aaggaaaggc aattttggca
     8221 accaaagtgc aatcctagtt ggatttactg aataaaatcc atttcctcta gtgaacatcg
     8281 aaaaaacttg tgttctcttc tttagtttgg tgttgaaaat agtttaacag acttttgact
     8341 tcttttatat gatataataa agtatagtat ttatgaaaag gacatataga gactgtaaaa
     8401 atatactttt gaaaagcttt ttagtctggg gtgttattgt agatagaatg cagaccttgt
     8461 cagtcctatt tacagtgtca aaatagtgcg ttttgaggtt ctatctacaa gcctaatcgt
     8521 gactaagatt gtcttctttg taaggtagaa ataaaggagt ttctggttct ggattgtaaa
     8581 aaatgagttg ttttaattga taaggagtag aatatggaaa ttaatgtgag taaattaaga
     8641 acagatttgc ctcaagtcgg cgtgcaacca tataggcaag tacacgcaca ctcaactggg
     8701 aatccgcatt caaccgtaca gaatgaagcg gattatcact ggcggaaaga cccagaatta
     8761 ggttttttct cgcacattgt tgggaacggt tgcatcatgc aggtaggacc tgttgataat
     8821 ggtgcctggg acgttggggg cggttggaat gctgagacct atgcagcggt tgaacttatt
     8881 gaaagccatt caaccaaaga agagttcatg acggactacc gcctttatat cgaactctta
     8941 cgcaatctag cagatgaagc aggtttgccg aaaacgcttg atacagggag tttagctgga
     9001 attaaaacgc acgagtattg cacgaataac caaccaaaca accactcaga ccacgttgac
     9061 ccttatccat atcttgctaa atggggcatt agccgtgagc agtttaagca tgatattgag
     9121 aacggcttga cgattgaaac aggctggcag aagaatgaca ctggctactg gtacgtacat
     9181 tcagacggct cttatccaaa agacaagttt gagaaaatca atggcacttg gtactacttt
     9241 gacagttcag gctatatgct tgcagaccgc tggaggaagc acacagacgg caactggtac
     9301 tggttcgaca actcaggcga aatggctaca ggctggaaga aaatcgctga taagtggtac
     9361 tatttcaacg aagaaggtgc catgaagaca ggctgggtca agtacaagga cacttggtac
     9421 tacttagacg ctaaagaagg cgccatggta tcaaatgcct ttatccagtc agcggacgga
     9481 acaggctggt actacctcaa accagacgga acactggcag acaagccaga attcacagta
     9541 gagccggatg gcttgattac agtaaaataa taatggaatg tctttcaaat cagaacagcg
     9601 catattatta ggtcttgaaa aagcttaata gtatgcgttt ttttgtggag atatttcctt
     9661 caatgtttgc tactatatta aacaaaaatc agaaagcaaa ctagaaagtt atgctcaaat
     9721 aaaatctaaa tttgacaatg taaaccgagt cggatagctt taagtactgt tttgaggttg
     9781 aagatacgat ttttgatagg aactcatcaa ttttagattt ttaagcagca tcaataaatt
     9841 gcttccttgt tttgtcataa tttttttatt taaaaaatta tgacaagagt gtgctattct
     9901 ttttatgaga ggtgtatgaa tatgataaat gtatgtgata aatgtatgtg ataaatgtat
     9961 gtgatgttgg aaaaagaata aaagaactta gaatatcttc aaatcttact caagataaga
    10021 ttgctgagta tttgtctttg aatcaaagca tgattgccaa aatggaaaaa ggtgaaagga
    10081 atatcacgaa tggatttaag taataaagct ccaaatctta gaaaaaagtt gggagctgat
    10141 ggtgaatcgc cgatagatat ttttaaattg gtacaaaaga tagaaaattt gacgctggta
    10201 ttttatggac tcggaaagaa tattagcaga gtctgttata aaggaactca gttcagtctc
    10261 attgcagtca attcagacat gtcattagga aggtaaagat tttctttagc acatgaactg
    10321 tatcatcttt attatgatga tgtgaagaag agttcagtca gtcttatctt gattggtgaa
    10381 ggagatgaaa ctgaaagaaa agcggatcag tttgcttctt attttttaat tttcccatct
    10441 tcactgtata ggatggttga ggaaattaga gaaaatgcca atagaactca tcttgaagta
    10501 gaagatatta taaaattggg tcagttttat ggtatcagtc ataaagctat gttatataga
    10561 ttgaggaatg atggatacct tgatgcagaa gaaattaaaa atatggatat tagtgttata
    10621 gagacagctt caagattagg ctatgataca agtttatatc gtcctttgtc agaaagtaaa
    10681 aaggaaacgg tattaggata atatattaat ttaactgaac aacttttaga aaataacaga
    10741 atttcgcaag ggaagtatga ggaactgtta ctagatgctt tcagatatga tattgtatat
    10801 gggctagatg aagaggggga gttgtcgttt gactagtcgt gtatttattg atgcagattg
    10861 tatttcagca tttttatggg ttggcactga acatctttta gaaaagctct attcgggtaa
    10921 aattgttatt ccacaagagg tgtatgatga aatcaatata cctacaattc cccatttaaa
    10981 atctaggata gaccagttgg taactaaggg ttcagctgag attgtgagca tagacattgg
    11041 aactgaagaa tacgcattat atagagattt aacaagaaat tatgatagta acaagattat
    11101 tggtaaggga gaagcgactt ctattttctt agcgaaaaag cataatggga tattaggaag
    11161 taataaccta agagatgtta aaccatatgt agaagaattt tctttagaac atatgacaac
    11221 aggagatata ctgattgaag cgtttaaagc gtaatttatt actgaacaag agggcaatca
    11281 tatctggaat aatatgctta aaaagagaag gaaaattggt gcaaattcat tttcagacta
    11341 tcttcgtgga agtattcacc aaaatagaca aaaataaatt tggataaatc gaactcacta
    11401 ttcaggaggc atatgagcaa ttcgaaaaag aaaagtgtca aattgagcct ataggagtag
    11461 aagtgaaata gtaagtcctg catagtggat gagagaaaag ttctccttga agttttcctg
    11521 aactatcagt cgcatgtcaa acgatatgta gggtaatgtg agaggggata gcgagtagtt
    11581 tttggttatt ttatcaaaaa ac
//
LOCUS       DAVMJI010000046        10762 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.047, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000046 DAVMJI010000000
VERSION     DAVMJI010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10762
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.047"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(54..470)
                     /locus_tag="VYR58_001836"
     CDS             complement(54..470)
                     /locus_tag="VYR58_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622937.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(482..1177)
                     /locus_tag="VYR58_001837"
     CDS             complement(482..1177)
                     /locus_tag="VYR58_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622938.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            complement(1371..3872)
                     /locus_tag="VYR58_001838"
     CDS             complement(1371..3872)
                     /locus_tag="VYR58_001838"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV3622939.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            complement(4327..5415)
                     /locus_tag="VYR58_001839"
     CDS             complement(4327..5415)
                     /locus_tag="VYR58_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV3622940.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(5433..6101)
                     /locus_tag="VYR58_001840"
     CDS             complement(5433..6101)
                     /locus_tag="VYR58_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV3622941.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            complement(6120..8558)
                     /locus_tag="VYR58_001841"
     CDS             complement(6120..8558)
                     /locus_tag="VYR58_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV3622942.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(8709..10007)
                     /locus_tag="VYR58_001842"
     CDS             complement(8709..10007)
                     /locus_tag="VYR58_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV3622943.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPTIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            complement(10024..10332)
                     /locus_tag="VYR58_001843"
     CDS             complement(10024..10332)
                     /locus_tag="VYR58_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV3622944.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(10378..10698)
                     /locus_tag="VYR58_001844"
     CDS             complement(10378..10698)
                     /locus_tag="VYR58_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV3622945.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
BASE COUNT         3295 a         2345 c         1768 g         3354 t
ORIGIN      
        1 actatataat actagaccat ccttaaattt tgcttaagaa aaaacaagtt ttgttatttt
       61 ttacgattca tccaagtcat ccctatacaa ttataggtgg ataagatttc aaagcccata
      121 gaacgataga agcccaaggt tctttctgtc tcttctgtca ccagctggac ttgataggca
      181 tctttgtaat cctctaaagc ctctttcatc aaggcactac caattccttg acgctgatag
      241 attggtaaaa cgattaaatc ctgaaccaat actgatgaga atccatctcc aaccaaacga
      301 atcaagccca ccacagcatc accatcaagt gccagataaa ttactaatga atgagataag
      361 gcctgctcca gcatctctgg ttgatgggta taatttgtcc aaccgacagc ctgatagaga
      421 tgtaaaacat cctctagctt gacaatttct tgctttttaa tagtaatcat ctcaacacct
      481 cttaaagttc tctcaagctc ttgtactgct gtccattttt atcaaaattt tcaggacgca
      541 accatgtttc caaacgatct ttgacttgag gccagtcctt atcaatcata gacaaccaat
      601 ccgtatctct cgtacgtccc ttataaacca ctgcctgacg gaaggttcct tcataaataa
      661 agctcaaacg ctccgcagct cgtcttgatg gcagatttaa ggcatcgcat ttccactcgt
      721 agcgacgata gtttagctcc tcaaaaacat agcgagctag gagatactga gcttcagttc
      781 ctatccgtgt accccttagc tctggagaaa aagtgactgc tccgacttct attactcggt
      841 tattctggtc aatgcgcatg agagaaaaag atcccaaagc cttaccagtc gccttgtcta
      901 tgattgcata gtaaaaacgg tccttacgag ccaacatctg atgtaaaagg ctaaccagct
      961 cccccatatc tgctactggc tcctgaaaaa ggtaggtcca catctcccga ggagtatccg
     1021 ggccataaac agctagcaaa tcctccgcat gcttttccac tgaaagagcc tctatcctag
     1081 cataacgccc ttctaagaaa tcaatagaag gcagttcacc tggtgtataa ccttccattg
     1141 actccccaat catttgacca tattcattta ctggcatagc tttctccttt tttcactttt
     1201 caaactttat agttgcccat agtataccat actttcataa gaagattcaa aaaatcctcc
     1261 agattctact ctgaaggatt cctaccttat ttcacaacga tattaacgag tttagttggc
     1321 tcaaacagtt tgggaaactg tttgaggttg gaaatcagca aataaattgg ttattttaca
     1381 acaatattaa ccaatttatt tggtacacta atcactttca cgatttcctt accgtcaatt
     1441 tctgctttga ctttttcatc cgctagagca atttcttgca attcttcacg tgataggtct
     1501 ttagcgacca tgagtttggc acggacttta cctttgattt ggacaacgat ttcgatttcg
     1561 tcttcaacca gtttactttc gtcccaagtt ggccaagcta cataagagat tgactcacct
     1621 gtttctgcga ctgtttgcca gagttcttct gccaagtgag gtgcaaatgg tgcaatcaat
     1681 tgaataaagc ctttggcata gtcaacataa agcttatctt ccttgttagc agcattgaca
     1741 aagaccataa gttgggcaat agctgtgttg aatttgagag actcaatttg ctcagtaaca
     1801 gctttgactg tttcgttgta agccttgtca agagcaccat tgttttccgc aaggatttct
     1861 ttacttgtaa tcaaacggta aactcggtca aggaacttac ggcttccttc caaaccttct
     1921 tctgaccaag caatcgaagc atcgagtggt cccataaaca tttcataaac acgaagggta
     1981 tcggcaccgt attgttccac cacatcatct gggttaacaa cgttcttgag cgatttagac
     2041 atcttggctg gcgcttgctc caactcttcc cctgtttcta tatgaaagaa ggaaccatca
     2101 cgtttttcaa ccttgtcggt tgccacaaga gcaccacggt ggtcacggta gcttgttccc
     2161 aaaatcatcc cttggttaaa gagtttttgg aatggttcct tagtcggaac aacaccgagg
     2221 tcatagagga atttatgcca gaaacgagca taaagcaagt gaagtacagc atgttccgca
     2281 ccacccacgt agatatctac tggcaaccat tgtttgagga ggtcctcatc agccaatttc
     2341 tcagtattgt gcgggtcaat atagcggagg tagtaccagc ttgaaccagc ccattgtggc
     2401 atggtgttag tttcacgacg acctttgaca ccatcttcac gagtcacttc aagccaatct
     2461 gtcaagttag ctagtggact ttcaccagta cctgaaggac ggatatcctt ggttacaggc
     2521 aagacaagcg gcaattcagt ttcaggaaca gctgttgaag ttccatcttc ccaatgaatg
     2581 attggaattg gctcacccca gtaacgttga cggctaaaga gccagtcgcg gaggcggtag
     2641 gtaaccttct cctgaccaca gcctttttct tccaagcaag ccacaatctt ggcaatagcg
     2701 tcttctttgt tcaatccatc taggaagtct gaattgacat gcaggccatc ctctgtgtag
     2761 gcagcttctt cgacatttcc accttcaagt acttcgacga ttggaaggtc aaattgtttg
     2821 gcaaattccc agtcacgttg gtcgtgggca ggcacagcca taaccgcacc tgttccataa
     2881 ctagcaagaa catagtccgc aatccagatt ggcatttcct taccattgac agggttgatg
     2941 gcataggcac ctgtccaaac accagttttt tccttagcaa ggtctgtacg aaccaagtca
     3001 gacttaaggc tggcttggtg tttatagtct gctacagctt ctgcttgctc tgaacttgtg
     3061 atagcgtcta ctaattcatg ttcaggagcc aagacagtga aagtcgcacc gaaaagtgtg
     3121 tccggacgag tagtaaagac tgtaaattcc ttgtctgttc cttttacttt gaaagttaca
     3181 ttggcaccag ttgatttacc aatccagttg cgttgcatat ccttgataga ctctgaccaa
     3241 tctagttcat ctaagtcatt gagcaagcgc tctgcgtaag ccgtgatttt gagcatccat
     3301 tggcgcattg gtttgcggac aactggatag cctccacgct cagaagttcc gtcaggaagc
     3361 acttcttcat tggcaatggc agttcccaat tcctcaaccc agtttactgg cacttcagct
     3421 tcataggcca agcctttttc gtaaagcttg gtgaaaatcc attgagtcca cttgtagtag
     3481 tttggatctg ttgtgttgac ttcacgatcc cagtcataag aaaatccaag cgcattgatt
     3541 tgacgtttga agttggcaat gttttccgct gtaaattctg ctgggtcatt accagtatcc
     3601 atagcgtatt gctctgcagg caaaccaaaa gcatcccaac ccattgggtg aagaacattg
     3661 tagccttgcg cacgtttgta acgactgagg atatcggttg cagtataacc ttctgggtgt
     3721 cctacgtgca gaccagctcc agacggataa gggaacatat caagcgcata aaacttaggt
     3781 tttgatgcat ctgttcctgt cttaaatgta tgatgttctg cccagtagcc ctgccactta
     3841 ggctcaattt ctttatgatt ataaaaactc atggtctctc tccaattttg tgatgttact
     3901 attataccat ttttgaggga atttgaaatg tgtttaaagg aaaaactgta tactgtatct
     3961 cattaatttt gatgactatg aattgctcta tctcccactt tttatcccat tgttatgcag
     4021 taaatcaagg agtaagtcaa gaagcttatc tcgtatagca caaaatactt attttagacc
     4081 gaagataaaa ctggaatgct aattaatgta ttcacaataa atagccgaca acctatgtcg
     4141 ctttttgatt tatgaagaac gtatagtgca ctgaatctga aatagtacga aacaattgct
     4201 aaaacattgt tagaaattaa ttttactttc ccaatcgatt tgttctcatc ttatttcaat
     4261 ctgctataga attcaatacg aggatcaata aaagactacc atttggaaaa cagtagtcct
     4321 tattgtttat tttgaattta cataggcatc tacagcgata atagcttgag caacatctga
     4381 aggcgaaatc ttaaacggca tctgatgaat tgtctcaccc tccatagttg cttgtttacc
     4441 aacttttatt aaatcatcat atccaacttg atccaaatgc atttctttta gagttgttgg
     4501 cataccaatt tttttgtaaa actcaatata cttatcaagt tcttctttag gtctattttc
     4561 caataatagt tgtactaaag ttccataagc tactttttca ccatgtgtta aatgatgaat
     4621 gtcacctgtc aatgcagtaa aaccattatg aattgcatgc gccgcagcta atcctccact
     4681 ttcaaaacct agaccactca ataaagtatt agcttcaaca atattttcta atgctggtgt
     4741 caccacttta gcttcacaag ctgccatagc ctgtaaacca tctgcaaaca gcgtttcttc
     4801 acatttcttc gcaattgcaa ctccagccaa tgtttgctgt tgtcccaaca tagtttttcc
     4861 atttgcctgc ataaccgcac gcgcctcaac ccaagttgct aaaccatctg caataccaga
     4921 cgctaataaa cgcttagggg cttgtgaaat aacttttgta tcaaccaaaa ctaaatctgg
     4981 atttttagaa taaaatagat aatgatcaaa tgcaccttca tctgtataaa taacagataa
     5041 agcagataca ggtgcgtcgg tcgatgcaat tgttggagca ataataacag gcttttcaat
     5101 caaatctgca atagcttttg cgctatcaat cgtctttccc ccaccaagac cgataatact
     5161 atcacaattt tctttctcag ccaaggcaac aactcgattg atttcattgt cagaagcttc
     5221 accattaaat agcgccagaa caatatggaa accataccta tgtagataat cttcaaatcg
     5281 ttttccaaca atatcataaa ccaactgatc gcataataga atagggcaat ttcccaaatc
     5341 caaaattgat ttggcatttt caaacaaggc attttccccc tgaatatatc tagaaggact
     5401 agcaaaaatt ctcatatgta tttcctctct atctaaatgg aacgactatt ttgaataaca
     5461 aaccagtcgt cagaaaagtc atcaaccgcc ttttggatag atggcatggc gaaagctgat
     5521 tcaaaaacat ctgctcctgc tgtaacagca tgcgcacctg cagctaaagc attatttact
     5581 tgtgctacat ttttaaagga tgcagctaaa atcttactag gagagttctg tctatcaata
     5641 gcaagagcta attgacgaat gacagaattt gaatcaatgt tcagattttc cattctatta
     5701 taatatggag ctaggtaatc cgctcctgct tcgatagcta ataatccctg aataactgta
     5761 taaatagctg ttgcagtgat atggtagccc tcttttttta gcacctttat tgcacgtaat
     5821 ccagctggag taacaggtac tttgataaat atatcatctc ctgcttgtct tcgaatttca
     5881 tgagcatcct ttaagatgcc ttcaaaatct tgagaaatca cctgaacatg aatagagggt
     5941 gtagagccaa tcaattctct tacatctttg attcgttcaa aaaaattaat agaaccctct
     6001 ctttttgcaa tagtgggatt tgaagttacc ccagctagcg gcaaaatttc agaccacttt
     6061 ttaatctcat ctaaatttaa tgtgtcaagc ataaattcca taaaaagaac ctctttattt
     6121 tacaaagtat gctcagtacg tcctataatg tcatcttggg ttgccttaga aagaacattg
     6181 aagaatgcag agtatcctgc aacacgaaca attaagtctc tgtgtttttc aggatgtttc
     6241 tgagcgtcaa tcaacgtctc tctggaaaca acattgtatt gaatatggta cccatgtaaa
     6301 cgattaaaga atgttcgtaa caaagcaatt agttttaatt tatcttcttc tttggctaac
     6361 gtttgaggat ttactttctg atttaagaga accccaccta cgatttcatc tgttggtaat
     6421 tttgaaacag attttaaaac agatgtaggg ccgtgttgat ccatattatg tgatggtgaa
     6481 caaccctctg ctaacggtgt acccgcgttg cgtccatctg gagttgctaa tgttccacgt
     6541 ccctgcccta cgttggctga tatagaagat gttcctgaat aacgaattcc tccaataggc
     6601 cctcttccat aacgtgtatt aggatattta gcaatttcat caacataaat gtcataagca
     6661 gcagtaacca atttgtcagc ataatcatca tcattaccat acttaggtgc atcatgaatc
     6721 aacatttctt gaatgacctt accttcttct ccggcataat ctgtttccag tgcatgccaa
     6781 agctgacttg ggcttatacg ttcttcctca aacaccaatt ttttaattgc agctaatgaa
     6841 tccgacaaat ttgcaattcc aacttgcaat cctgatatat aatcatatac tgctccacct
     6901 tctttaaggt gttttccacg accaatacaa tcatcagtca atgctgaaca tagaatatca
     6961 ggaacttctc gttccaatga taaatcaata gaattttcaa caataacact cattcgtgtc
     7021 aaatatctta gtgttttatc ccaagcattt tctaattcag aaaagttctt catatcctta
     7081 aaatgaccaa agcttggtgc aaaccgttta cccgaagccg gatcaattcc atcattcatc
     7141 gtgataagta gaaccttagg gaagttcata taactcatac ctgtgcaacg atagccccat
     7201 ttccctggaa ctgccgtttc aacacatcca atggcactgt aatcataagc atcatcttcc
     7261 aatactcctt ttgcaataaa agaaggaata ataatctcat cattattaaa tgcaggcata
     7321 ccaaaaccaa gtttcatcac ttcaatacac tcattcatga aacgagcatc taaacctgca
     7381 tggtaacgta cagttagatt aggttgcggt agatgggttt gtgcaactga ttttaatacc
     7441 aaataagata atgggttaac agcatccttc ttatctcgag tctgtccacc aattgtaaca
     7501 ttttgatata aaggacttcc tgctgaagaa aatgtatgtg attgactgcg aaccttatta
     7561 attgtaattg tcttaatcca aagatttgtc agacgttcaa caatgctatc ttctgtttct
     7621 ttaccacttt ctaaatcagc cttcatatat ggatacatat attgatcaaa acggccatat
     7681 gaaagagagt ggccattaga ttcaatttgt aaaatacatt gaataaacca aactgattga
     7741 atagcttctg caaaagtagt tgccggttca tatgggactc tagagcaaat atctgcaatc
     7801 tcaagtaatt ctttcttacg tttaggattt gcattttcgg ctaaactttt agcaagagca
     7861 acaaagcgct ttgcatatac tttaatagca tcgattacga taaatataga gtcgtaaaaa
     7921 tgatatttat caatacttgc tggatctgtt aaatctagag ctaccttcgc tttacgagcc
     7981 cgctcttcaa aacctcttaa accaaattgc aaaagtttct gatagttaac tgctaagtga
     8041 gcatctccag aattcatctt accttccata ccgaagaatc ctgtttccat ataaacagac
     8101 acttcttcag gtaataaggc accagctcta gcacgtaaat tattattttc ccaaaacgga
     8161 gcaatacttc taagttgttc ttttgtttct tctgtaatat agaaaacatc tccatcacgc
     8221 ttttcaaaaa gatccaactc attgagaaca aattctagcg tatattccgg aaaaatagga
     8281 gcatctttat tggaagaagc ttgatttccc gcaatcatag attcttcttc aatatagata
     8341 gacatatttt ccaaaatttc tttcagcata tatgcacgtt ttaggacatt aggttgttcc
     8401 ttgtatcgtt cataggcgcg tgttgctaga actgctctct cagcatcaat ataaggtttt
     8461 ttatttaaaa catcttctcg atatttgttc atcctttcag taaggctgcc aaaatattct
     8521 gtcttgattg ttgttcttgc tacttctgta tttaccatcg taagcacctt tctttcgaaa
     8581 atatttttat ttctttcgaa aatataatac cgatttttat agaaattttc aagcttttaa
     8641 ctagaaaaat tttaactctc taatttttag cacaaatgtg tgagtttaac agtaacacac
     8701 aaatacctct aagattgttt gatttcattt tggtaagcta aacgatcttg tatcttaaag
     8761 aatggaaagt aaaccactgt agatatcacc aatactaata actgagtcac aacaccttgc
     8821 catccaccca ccaaaaatcc tgatagaata gctggtgtac tccaaggcaa tgttacccct
     8881 gagaatggtt gcatgaaacc tgttgcaata gctccatata ctatcacagc tgcaagtaca
     8941 ggaacaagaa tgaaaggtac aaacataact ggattcatga caatcggaaa tccaaataca
     9001 actggctcat ttacgttaaa tattgttgga aaagctgcaa cttttcctaa ggcttggtat
     9061 tgttttgatt ttgctgcaaa aagcatggca actacaagac caaacgtaat ccctgaacct
     9121 gatagaatta aaaatgaatc taaaaattgt tgagtaacaa tatgtgcacc attttctaat
     9181 gatagattac cagaggctaa catagcttta ttagcatcaa gattagataa aagcagagct
     9241 gtcactactc catttactac cgattgccca tgaacaccaa accaccacaa aaatgatata
     9301 aagaatgcaa ttccaatagc accatacaaa gatccagtta aaccttgcaa cggaacttga
     9361 atagcagaat aaatcatttc tatgaatgtt ccgccattag tcaatgactt cgctaaaata
     9421 tatacaatca tagaagataa gaaaattaca aatgctggaa tcattgcttc aaactgtttg
     9481 gcaatagctt gtggaacttg ttctggcatc ttaataacaa tttttctctt tataaagaag
     9541 gtataaatac ttcctactac caaacctata atgatagcac cgataattcc ttggcctcca
     9601 aaccaaactt tactaatagc gtccccaatc gcctcacctt gtttagggat ataagacgat
     9661 cttagcaaaa taaagaatgc agatacagat agaactccag ctggtaaagc ctctactccg
     9721 ctattcttag cataagaata ggcaattgaa aaacaagaaa ttagacccat aatagcaaaa
     9781 gttcctgaat atacttgcat aaacggctct gtccaattag ctccaaaaac actagcaatg
     9841 ctcttattta atccttcgaa cggcaattgt cccataatca agaacaaact accaactact
     9901 gtcaatggta aaattgctaa catcccatct tttagagcta taatgccacg catattcaca
     9961 aacttcatca tcggtgcaat gattttctga acatccatct ttgacataat aaatctcctt
    10021 ttcttaccca ctaatcaaag atagggccaa atctaatact tttttcccat ctaacatacc
    10081 atagtccatc atcggaataa cagctatcgg aacatcacac ttatcacaaa tttcttttga
    10141 tttatctaat gtataagcaa cttgtggacc caatagtgca acatctatat ttggcgcata
    10201 atccgctaat ttagactgag aaaacgcctc tatttctgcc tcaactccac tagattgcgc
    10261 tgcaattttc atattattta caagcatacc agtagaaaaa cctgctgcac aaaacaaacc
    10321 aatcttcacc attatgtttt cctcctctat gttaataaca atgataatac tctagtatta
    10381 ttttttatga agttcttttc tcaaactaat aatttctttg attaaattaa tctccgtcat
    10441 actagtcatg agatgatctt gtgaatgaac aaagagagct gtaatttctg tctttgtacc
    10501 agacgcttcc tgtgccaaga attttgtttg tagattatga gcttctaata aggctgcatc
    10561 agctaactgg atttcttctt cacatcgttc acatgtaccg ttctttatgt aatctaatgc
    10621 tttataaata tgttgtttcg catcgccagc atataaaatt aaacccatga taatttgatc
    10681 tggaacaata atttccataa attcctcctc atttcactat gtaaaaagct tttttcattt
    10741 gaaattttaa aattttcttt tg
//
LOCUS       DAVMJI010000047        10753 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.048, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000047 DAVMJI010000000
VERSION     DAVMJI010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10753
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.048"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(105..1529)
                     /locus_tag="VYR58_001845"
     CDS             complement(105..1529)
                     /locus_tag="VYR58_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV3622946.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2074..4353)
                     /gene="pulA"
                     /locus_tag="VYR58_001846"
     CDS             complement(2074..4353)
                     /gene="pulA"
                     /locus_tag="VYR58_001846"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV3622947.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4472..6430)
                     /gene="ligA"
                     /locus_tag="VYR58_001847"
     CDS             complement(4472..6430)
                     /gene="ligA"
                     /locus_tag="VYR58_001847"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV3622948.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6523..7701)
                     /locus_tag="VYR58_001848"
     CDS             complement(6523..7701)
                     /locus_tag="VYR58_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV3622949.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LNMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7781..8644)
                     /locus_tag="VYR58_001849"
     CDS             complement(7781..8644)
                     /locus_tag="VYR58_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV3622950.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQKAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8647..10548)
                     /locus_tag="VYR58_001850"
     CDS             complement(8647..10548)
                     /locus_tag="VYR58_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV3622951.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKYSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3234 a         2366 c         1908 g         3245 t
ORIGIN      
        1 gtttcaatct attataatac caaaaagttc gtattttttc tataattatt attattttat
       61 agcaaaaaaa taaaaccagg aaaacaattt cctggtttta cacgttattt cacatcaaaa
      121 acaatggatt tgacatttgt catcgcttca atgctatatt taattccttg cactccagct
      181 ccagaacctt tgacaccaag gaatgggaaa ttatctggac cacgctgggt tttattatta
      241 atgtggactg tacctacttc aagtttttca gcaatttcaa aggctttttt gaaatcattt
      301 gtaaagactg atgattgaag gccgaattca gattcgttgg caaaggcaat agcttcctct
      361 acactagcca cacgaatgat tggtaaaaca ggaccaaatg gctcttccca tgccactttc
      421 atatcttttg taacttggtc aaaaagcact ggccagagaa gattgccctc acgtttgatt
      481 ggtgtaagag cctgagcttc tttttcttgt gcatcctcaa tcaagcccca aatgaagtcg
      541 gctgaagcat tgtcaataac aggtgtaata tcagcattgt caaatggatc accaactgtt
      601 aatttagaaa cttcttcctg aagcaaagta gctaatttat ctgctacact ttcgagaaca
      661 atgacacgtt taatggccgt gcaacgttgt cctgagtagc taaaggctcc cgcaacaatt
      721 tgcttggcag catgttccaa atctgcatct tctagtacaa gagctgcatc tttcccacca
      781 agttccaaca tgataggacg cataccagct aaacgaccaa tacgttctcc aataggagtt
      841 gaacctgtaa agttgatgaa gttgacttct ttgtgctcaa tgatataatc cccaatttct
      901 gaaccacgac ctgtaatggt gttgaaaaca cctgccggaa tccctgcttc ttcaaatgct
      961 ttagccaaca agagtccaga aatggaacct tgtgttggtg gcttaaacat gaccacattc
     1021 cctgcaatca aggcaggtgc aattttagaa gcagataaat taactggata attaaaggga
     1081 gcaatcgcta gcacgatacc aactggttca cgacggacaa cagccagttt gtttttactt
     1141 gctgcctcaa aaccaccacc ttccattgct tgtccagtga tacggagacc ttcctcagca
     1201 gcataacgaa tcaagtctgc tgtacgcact acttctccaa ttgctgcttt aatccctttt
     1261 gctacttctt tggcaaggat agtaccaatt tcttccttat cgcgttctaa aatagctgct
     1321 gttttatgta aataagccgc acgttcaact gctgataaag ctcgccatgc tggcagggct
     1381 gcacgcgcag cttgcatagc ctcatcagct tcagtctgag tcatggctgg aactgtaccc
     1441 aattcttctt gattgattgg tgaataaatc gtaatttctt gttcagatga tttccatttt
     1501 ccatttacta aattctgata tcttgtcaaa ttcttgtcct cctgaaaatg attaagatat
     1561 attttaccaa attttcagaa aatcacaacc ctttttgcaa aatttttgag attattttca
     1621 caaacttgat ttttcaaagt atactcaata aaaataaaaa aaatccacta cgtcaaggcg
     1681 aggctaatgt ggtttgaaga aattttcgaa gagcgtgaat gagtatcatc tatagtaaaa
     1741 taaaaaaact gaacaatttg gttggggaca gccaaaccaa tttctcacaa tgtttcagaa
     1801 acaagggtgt gctactccaa tttcagccta ctataactgt catagattgc tgaaacaaag
     1861 tctaggtaaa agtcttcata ataaaaagac ctcctatcaa gtgttcaaaa actttgatag
     1921 gaggtcttgt tttgtgaaaa tatttatcaa attttctata caagtgagct gttagccagg
     1981 ttctttctat tctttcaatt tcaatgaatg gattttttac taatactcat aactgggaat
     2041 ttgtctgtgt aaaaatagcg agatagatgg tatttataaa acactcaaga cagctagact
     2101 aatatcattt aaaacattat cttcttttga gcgactgttg gttaccaaca tagctaaatt
     2161 tcctgcattt tcaaattgat agggttctga tttagcattc acaaccacca agaggtgttc
     2221 tttgccgtga acttcataga taaggtagcc gctatgttca atcgcagaat gcacaaagac
     2281 atgatggtaa atttcatcat agctagagta agaaaaggca ccagtttttg tcttcaatcg
     2341 gatgacttga cggataaact caatactgtc ttgacgctca ttaatcaagt tccagttcac
     2401 ttggttcaca ctgtcaggag cattatagct attcatcgca cgctctctat catcatgggt
     2461 caactcacca ttttcaccag tcgcaaccag tttggtacga ccaaattctt gaccgatttc
     2521 cataaaggcc atcccctgca tgagcagatt catggctgtg gcagtttcga ccttgcgcat
     2581 gatttgctct gaactttggt ctggatgaag ggttgccaat aaatcgtgaa gattgtaatt
     2641 gtcatgggct tctacatagt taagcacctg atttggatgt gtatagcttc ctaattcacg
     2701 acttcctagg attgctttag ctagaattgg ctctgtcgca gcaccactga caaaacctga
     2761 cttgatagca ccataaactt ctcccccttt gacagcatcg cgctgattgt cattaaagaa
     2821 accaatattt ggcatctggt aggcattgtc cttcttggcc ttatcataag gggcaagacc
     2881 tgttcccata tcccatcctt ctccatagag gataatgttg gagtcgattt catccaagct
     2941 ttgacgaatc atctgcatgg tcttgacatc atgaatcccc atcaagtcaa aacggaagcc
     3001 gtcaatatta tattcctgca cccagtatag aagagaatca atcatatact tgcgaaacat
     3061 ttcgtgttca ctggctgttt catttccaac acccgttcca ttctggaagg taccatctgg
     3121 attcatacga taatagtaat cagggactgt tgtttggaat ggtgcatcaa caactgagaa
     3181 ggtatggtta tagactacat ccataatgac tccaataccc gcatcgtgat aagcttgaac
     3241 catcaccttc aaatcacgaa tgacctgagc tggatcatct ggattagttg aaaaactagt
     3301 ttctggcgcg ttatagtttt gtggatcata accccagttg taggttacat ttccatcctc
     3361 atcgtattct ttatgacggt ctgcaattgg ttgcaattga acataattgt agcccagctt
     3421 cttgatgtaa tcaaaagcag ttgactggcc gtattggtta actgttccag cctgagcagc
     3481 acccaagaaa gttcctcgaa gatgttcatc tacacccgat gtaggtgatt tagtcaaatc
     3541 acgaatatgc atttcacaga taactgcctt acatggattt tccaagcgcc aagtagcctc
     3601 cgaaccgtgc ttaacctcga agttttcaac ttgcttttct acatggctca gaatagctga
     3661 acgtttgcca tcagggctgg tcgcgattgt ataaggatca cgtgtcagtg tttggtgatg
     3721 agggaattgg acttgatact gataagcctt acctaccaaa tcttcctcaa catccaaact
     3781 ccagacaccg attgtattgt ccttatgatt ataagagtag ctattgcctc ttttcatctc
     3841 aaaagtcttc caaacgggtg catcattagc agctgattca taaacgacaa cttgcacttc
     3901 tgtcgctgta ggtgaccaga gggaaaaatg agcctgattg tcctctacac ggcaacccaa
     3961 ttctccttgg taaccccaat gatggtcaaa actagcactg ttaatggcct tatcaaaggc
     4021 aaaaggattt tgatttttat agaaaggact ggcaatagca ggattttcag agtaataaat
     4081 cctatcatcg ccttccaaaa tccagacctc tgttaatagg ggatagtgat taaaacggat
     4141 agaatattct ttactagttt gacctgtatg aaccacaaaa ttcaagcttt ctataacatg
     4201 tgaacttggg tgttcaaagc taaataaagc tccaaaataa tcttctttgt aggttagcaa
     4261 atcaattcgt tgatcctgac tttttacaaa ggagcaagtg tcatattctc cattcttacg
     4321 atggtaatga atgcgcatag ggtagttata cattttttat tttttatttt tcctttttac
     4381 tttgtttcta tttcactaat aaatttttgt caatctcgtc tcaattaaca gacatagtca
     4441 tattctctaa actctgtttt taaacgatcc attacaaact ttctagccat gcctcatctc
     4501 tgacctggat accaagttct tgtgcttttt gcagtttact tccagcgtct gcacctacca
     4561 cgacgaggtc ggtcttttta gaaatactac ctgtcacttt ggcacccaga ctttcgagtt
     4621 tacttttagc ttctgagcgc ttgagtcgtt ccaattttcc tgtcaatacc acggtcaaac
     4681 ctgacaaggc cgcatccgct actaccgtct gtcctttata gtccagattg accccagttt
     4741 ctttcaattc tctgagcaga atttcagagc cttctgtcgc aaaataagtc tgaagacttt
     4801 tggcaatcac gccacctaga ctttcaatac tagccacttc ctctgaatct gcctgagaca
     4861 gattttcaat tgaatggaaa tattgaagta aaagctgact aaccttgctt ccgacatgac
     4921 gaattcccaa accaaataag agcttctcgg cagaattttc ctttgatgct tggatagcct
     4981 gatacagttt agcagcggac ttttccttaa ccccctctaa aaggaggaaa tcctcttctt
     5041 gcaaacgata aatatccgcc acatccttga ctaaattagc agcaaaaagc ttctcaacaa
     5101 tagatggacc aaggcctgta atattcatag catcacgaga agcaaagtga atcaagcctt
     5161 ccatgatttg agcagggcaa cgcggattga tacaacgtag ggccacttca tcttcaaagt
     5221 gcaacaagtc agagttacaa cttggacagt ttgtagggat atctagtttt tcttcagaaa
     5281 cccgtttgga ctctaccaca cgtaaaacgg cagggatgat gtcaccagcc ttatatacaa
     5341 tgaccgtatc gtcttttcgg atatcttttt cagcaatata atctacattg tgcagggtcg
     5401 cacggctaac agtcgtaccg gcaagttgta ctggtgttag attagcagtt ggagttacaa
     5461 caccggtacg gccaactgtc cagtcaactg ataagagttg agcttctttt tcttcggcag
     5521 ggaacttgta ggctactgcc cactttggag ccttaactgt aaaaccaagt tcttcttgac
     5581 ttgctaggtc gttgaccttg attaccactc catcaatatc gtaaggcaga ttttcccgtt
     5641 cctgtcctac ttcttggata aaattccaga tttcatctat gttttcagcc aagattcgct
     5701 taggattgac cacaaaacct agttgttcta ggtacttcaa acccttttct tggctatcac
     5761 gagttgaagg gctggcttct tgatagagaa acgttgcaag attacgcttg gcaactactg
     5821 ctgtatccaa ctgacgcaga gttcctgctg ccgcattacg aggattagca aattcaggct
     5881 ctccattttc ttggcgcact tggttaactt ggtcaaagga agcgcgtggc atgtaacatt
     5941 ccccacgaac tgtgatatct agttcttctg gcaaagtcaa agggatgtcc ttaacacgct
     6001 tgaggttttc tgtgatattt tcaccaattg aaccatctcc acgtgttacc ccagcaacca
     6061 aaatcccctt ttcataagtc agcgagatag ataagccatc gattttcagc tcacaaatat
     6121 aggtcggatg agccacttcc ttacgaacac gcgcatcaaa agcatctagc tcctcacgtg
     6181 aaaaagcatc ctgcaaacta taaagaggat actgatgact gtatttttca aaaccatcta
     6241 aaaccttgcc accaacacga tgagtcggac tgtctgctag cacttgctct ggataagcag
     6301 tttctaactc gaccaactca cggtaaaggc ggtcatactc actgtctgca accgagggat
     6361 tatcgctggt atagtactca gtcgcatagc gattgagcaa agcgactaac tcattcattc
     6421 ttttattcat aagaccattt taccataaaa caagccctcc tcacaaacga gaagggcgga
     6481 aaaaacactt agtttgaaat tatttttgaa actcaagcaa ccttatatca atttttcaaa
     6541 atgagttcga acataaataa acgatataca agacaagatg ataacaccac ttccaattat
     6601 caggaaagaa gagagatgta cacttggcaa gactgtcata aatccttttg caataggcat
     6661 aaatagaata gctaaggtaa aaattgtact cagtactctt ccaagaaatt cgctctcaac
     6721 cttggtttgt acttgagtaa aaaagtgaat attaaaaatc gtcataaaca attcacaaac
     6781 taaatttcca gaaaaggaaa gaaaagttgg aagtggtaat cccatcataa aaactccgac
     6841 acctgtcaaa gccagtaaaa tcaaaagatt ataaatatta gctttaattt tactagctag
     6901 aagagcccca atgatggaac caatagcccc catagttaaa atacttgcat aggctccttc
     6961 tgacccgtaa agctgattcg aaaagggaag tagaaattca aaagctgcaa aaaagaaatt
     7021 aacgctggaa gctaccagca aaaggaagaa aatttcttgc tgatgccaga tatagtgtaa
     7081 cccatccttg atatctacaa aaatatctct cccagtaaaa gcctttttct cttgaacttt
     7141 tgcttcctct tttggaagga aagccactag aacaaaagca atgaaaaaag tcagcgagtc
     7201 tagcagtagc gtcatattga gacttgcaaa ctgtaaaaca aggaaggaaa gaacaggaga
     7261 gctaacacct acaacctgca aaaccagctc taagcgagaa ttatagatca caatctcatc
     7321 tttctccacc acttcagtta tgatagcttt attggctgtg cgagaaaagg caaaagcaat
     7381 agcctgcaca atgttagcaa caatcaaagc gccaatcatc cagctatcat tccttatgaa
     7441 agaaatagcc agacaaagaa tcccacaaac aagatctgcc gtcattaaaa tcttacgacg
     7501 agaaaaacgg tctgaaataa ctccgccaaa gggattgacg agaatagatg tgacgagctc
     7561 agaaatctga tacattccta aaactgtctg tcctatagtc cccatagaag ccaaccagac
     7621 actatttcca taatcataga gcatatttcc cattttattg atagccccac ggctaatcaa
     7681 ctgcactgca tagcgattca tattaaagct cctctcaaat tttgaaacta ttgtatcaaa
     7741 accgaaagga gctttttatt ttttccctta tttgggaaaa ttaacttttg acaaattttt
     7801 cgtagtgttc ctgataatag gctacttgct ctggaagacc taacacatca aaaatatgca
     7861 tggccttttg catctgctta cagccttctt tacactgtcc tttttgatat aaggcaaaac
     7921 cttttaaata atggaaaaca ttacgctcat aaagcttaat acctttgtca ataatcttct
     7981 ctgtataagc ctcaaaatag ttggcattat aaaaagaaga atgctctaaa caatgctggt
     8041 aacaattgag ggccaaaatc aaaactaatc tcttatggcg actaatctct tggtaaaatt
     8101 cctccctctc cataacttct ctaccaatcc gagtgacata gtctacatcg tagaaactat
     8161 agaggttacc gaaaagaatc aactcataca tggtccattc ttctgttttg aagagataat
     8221 ctgctacctt atccaaatca tcctgcttca tatcataagt cgcatctctt tgacaaatca
     8281 gaccttgtag caaaatccag ttcagctcaa aataaaggga agtcgtcgaa ctcttagact
     8341 tttcaagttg ttctctttga agcttttgaa aacctgcaat atcgtttgaa tagtaaagtg
     8401 ggataatctg tgccatcata gacacatgtt catgattatg aaaattcctt gccttatcca
     8461 tgaaattttc gattgttaca tgaatgttat ccaaaatctc aaagaaacgg gagactgcca
     8521 ggtcagactc cccaagctca aagcgagata actgagaggt agagcaggat tcgcctgctg
     8581 cttcctttaa agaataattt ccacttgttc gaaattcacg aaatactttt ccaagatgtt
     8641 ccatctttac acctgatctg ataattcttc ccactcaagc atagcttctt cctgacgatg
     8701 gctgattttg tccagctcag cctgtaattc catgagtttg tcggcatcgt ttgtttccaa
     8761 catttgttca gaaatggctt ggctttgact ttctagctct tcaatttcag cttctagact
     8821 ttcgatttgt cgcatgagtt tgcgaacttc tttttgactt tctttctggg cctgatagtc
     8881 attgactgga cttgcttcct ttgcttgatt gctagttgaa gcttcctcag tctgactcat
     8941 ttctgctgtt gctttcttct caacatagta gtcgtaatct ccaaggtaga gagttgaacc
     9001 attctcagac aattccaaaa catgagttgc cacacgattg ataaagtaac gatcatgact
     9061 gacaaaaagc aaggtaccat caaagtcaat caaggcattt tctagcactt ccttactatc
     9121 aatatccaag tggttggtcg gctcatccag aatcaaaaag ttattgtttt ccatagacaa
     9181 tttagctaaa agcaaacgag ctttttcgcc accagatagc atgccgactg attttttaac
     9241 atcatctcct gagaaaagga aggccccaag acggttgcgg atttcaactt ctggtgtcag
     9301 tttgaaatca ttccagagtt catccagcac cgtattactt ggtgtcagct tgctttgggt
     9361 ttggtcatag taaccaacct caacattagc gccaaagcgc ttttcacctt tgataaaagg
     9421 aatctggtcc acaatagact tgataaaggt tgacttgccg ataccatttg gaccaacgat
     9481 agcgacagca ttcatcttac gaagatctag gttgataggt tgtgacaaaa cttccccgtc
     9541 ataaccaata gcagtatttt caacagtcaa aacaacattg cccgacgttt tttcagactg
     9601 gaaggtcatg ttggctgctt tcttgccagc ttcaggcttg tccaaacgct ccattttttc
     9661 tagttgttta cggcgagatt gagcacgttt ggtcgttgaa gcacgaacta gattgcgatt
     9721 gacaaagtct tccagagcag cgatttcctt ctgttgcttt tcatagtttt ttgcctcagt
     9781 agctagcttt tgctccttca actcaacaaa acgagagtaa ttccccacat agcgatccaa
     9841 ggaatacttg gtcaaatcta gcgtaattgt cgcaaccttg tccaagaaat aacggtcgtg
     9901 gctgacgata atgagggcac cgctatagtt taccaagtaa ttctctagcc aggagatggt
     9961 ttcaatatcc aagtggttag ttggctcgtc caagaccaag agattgggct tttcaaggag
    10021 cattttagct agagccaaac gagtattttg accaccagaa agctcagcaa ttttcatctg
    10081 ccacatagac tcgtcaaact tgaatccatt caaaatcgct cgaatatcag cttcataggt
    10141 aaagccacct gcttggcgaa aattttcaga taagcggtca taatctgaca tcagtttatc
    10201 caaatcctca ccagactttt cacccatctc cagctccatc tgacgcagtt gtttatctgt
    10261 ccgacgtaag tcatcaaaga catgaagcat ctcatcatag atggtatttt cagactcaaa
    10321 acggctatct tgagctaggt aagacagaga aatatctttt ttcttattga tttctccact
    10381 agttggctcc tcttctccaa ctaaaatctt caaaagagta gacttacctg caccattttt
    10441 cccaacaagg gcaatccgat ctcgttcatc aacctgcagg ttgatattat cgaaaagaac
    10501 ctctcctgca aaagaacgtt caattttatt agcttgtaaa ataatcatac aagtagtata
    10561 gcatgtttcc ctaaggcatt caagataatc gtaagtcttt tagtacaact tttataacat
    10621 aaaataaact aaattatgta tattttatat tagattcctt cactatcttg ttggattttc
    10681 taaccagcta atcttgtttc aaatagttat cgcacaagcc tattatttaa ttcttttcat
    10741 tatttacgta cgc
//
LOCUS       DAVMJI010000048        10031 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.049, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000048 DAVMJI010000000
VERSION     DAVMJI010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.049"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(50..1753)
                     /gene="ilvD"
                     /locus_tag="VYR58_001851"
     CDS             complement(50..1753)
                     /gene="ilvD"
                     /locus_tag="VYR58_001851"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV3622952.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1986..2918)
                     /locus_tag="VYR58_001852"
     CDS             complement(1986..2918)
                     /locus_tag="VYR58_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV3622953.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2915..3772)
                     /locus_tag="VYR58_001853"
     CDS             complement(2915..3772)
                     /locus_tag="VYR58_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV3622954.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRLTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3776..5122)
                     /locus_tag="VYR58_001854"
     CDS             complement(3776..5122)
                     /locus_tag="VYR58_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV3622955.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5135..5419)
                     /locus_tag="VYR58_001855"
     CDS             complement(5135..5419)
                     /locus_tag="VYR58_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV3622956.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5423..7453)
                     /locus_tag="VYR58_001856"
     CDS             complement(5423..7453)
                     /locus_tag="VYR58_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV3622957.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7645..8652
                     /locus_tag="VYR58_001857"
     CDS             7645..8652
                     /locus_tag="VYR58_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV3622958.1"
                     /translation="MTEKLINSKPNGVFALILIELTLVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQNRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8655..8855
                     /locus_tag="VYR58_001858"
     CDS             8655..8855
                     /locus_tag="VYR58_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV3622959.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9007..9189
                     /gene="rpmF"
                     /locus_tag="VYR58_001859"
     CDS             9007..9189
                     /gene="rpmF"
                     /locus_tag="VYR58_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV3622960.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9205..9354
                     /gene="rpmG"
                     /locus_tag="VYR58_001860"
     CDS             9205..9354
                     /gene="rpmG"
                     /locus_tag="VYR58_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV3622961.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9834..>10031)
                     /locus_tag="VYR58_001861"
     CDS             complement(9834..>10031)
                     /locus_tag="VYR58_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622962.1"
                     /translation="ESGSMATGWVKDKGLWYYLNESGSMATGWFTVSGKWYYTYNSGD
                     LLVNTTTPDGYRVNANGEWVG"
BASE COUNT         3260 a         2133 c         1614 g         3024 t
ORIGIN      
        1 tacggcaagg cgacgttgac gtgatttgaa gagattttca agtatgagtt tattttttac
       61 ctgacttgtc catattccag aagtctgtca cggctccgcg tgaagcagat gatacgatat
      121 gggcatattt accgaggaca ccacggctgt aaagtggtgg caaggttgtt tctgccttgc
      181 gtttttcaag ttcttcttcg gatacggcca tggaaatttc tttggtatct tggtcaaccg
      241 taacgatatc gccggtacgg agataggcaa ttggtccacc atcctgagct tcaggagcga
      301 tatgtccaac aaccagacca taagtaccac cagagaaacg tccgtccgtc aagagggcca
      361 ccttatctcc ctgaccttta ccaacaatca ttgaagaaag tgacagcatc tcaggcatac
      421 caggaccacc tttaggtcca acaaaacgaa caacgactac atcgccatca acgatttcat
      481 ctgtcagaac ggcctgaatc gcatcttctt ctgagtcaaa gaccttagct ggcccaacgt
      541 gacgacgcac tttaacacct gataccttgg caactgcacc gtcaggagca aggttcccgt
      601 tcaagatgat aagcggacca tccgcacgtt ttggattttc aagtggcatg ataacttttt
      661 ggcctggagt caagtctgca aagtcagcca agttttcagc tacagtctta ccagtacatg
      721 tgatgcgatc tccgtgaagg aaaccatttg ccaacaagta cttcataacc gcagggacac
      781 caccgacttc gtagaggtct tggaagacat actgaccaga tggtttcaag tcggccaagt
      841 gaggcacacg ttcttgaatc gtattgaagt cctcaagtga caagtcaaca tttgcggcat
      901 gggcaatggc gagcaagtga agagtggcgt ttgtagaacc accgagagcc atcgttacag
      961 taatagcatc ttcaaaggct tcacgagtca agatatctga tggtttgaga ccaagttcca
     1021 acatcttaac aacagcacgt cctgctgctt cgatatcttc tttcttatca gctgattcag
     1081 ctgggtgaga ggatgaccct ggcaaactca tccctagaac ttcgatagca gttgccatgg
     1141 tattagcagt atacatacca ccacaaccac cagggccagg gcaggcatta cattcaagac
     1201 gtttcacgtc ctcagctgtc atgtcaccgt ggttccattt tccgatacct tcaaagacag
     1261 aaaccaagtc gatatcttta ccatcaagat ttcccggtgc aatagttcca ccataggcga
     1321 aaatagctgg gatatccata ttagcaatag caatcataga tccaggcatg ttcttgtcac
     1381 agccaccgat agcgacgaag gcatccacgt tgtgaccact catagccgcc tcgatggagt
     1441 ccgcgatgat gtcacgagat gttagagaga aacgcatacc aggcgttccc atagcgatcc
     1501 cgtccgctac ggtaatggtt ccaaactgta caggccaagc gcctgcagat ttgacacctt
     1561 ctttagccag tttcccgaaa tcatgcaagt gaatgttaca tggtgtattt tccgcccaag
     1621 tcgaaatcac tcccacaatc gatgtttcaa agtccttatc tgtcatacca gtcgcacgaa
     1681 gcatagcacg gttaggtgat ttaaccatgc tgtcatagat gctactgcgg tgacgtttat
     1741 ctaattcagt catcttatcc ctcccatttc agtttttact attatagcac aatttaaagg
     1801 caatgaacag aataaaattc ttgaattttc agaaaattct atacgcatgt gaaatattta
     1861 aaattaaaaa caacaaagcg gattagtgca ctttctgatg accagaatat gctttttaat
     1921 ccgctttctt taaataacgt actgtaattt ttacagaaat tctttcagat aagtgtattt
     1981 aacatctatc ttgcattata aatttctaga accttctctt ttatattcga ttcactcaaa
     2041 ccatactcat taagaagata atccattttc cctacttgac caaatctttc ttgaacaccc
     2101 atccgatgaa tttttgtcat tccatcatca gagaataatt cacataaaga actgccaatt
     2161 ccacctatct gattgtggtt ttctacagta aatatagttt ttccacttaa cattgttttt
     2221 atctgttctg gtatcggttt gattctaaat aaatctatca cacttactga ataacctaat
     2281 ttagacagtt catctgcaac tcgaatactt ggagcaacca ttataccaga agcaacgatt
     2341 acaagatctt caccatgcct taactcaatg tagcctttag aaaaatcttc tccaccttga
     2401 tacacaggaa ctggagcttt tctaattgtt cgaatatatt ttagtccttt taagtccaat
     2461 gtctggttca atatttcacg aaattggata tcatcagttg cttcaaaaat gatcgattta
     2521 ggaattaaac gtaacaatcc aatttcttca aatggcatat gtgtcccacc attcatttct
     2581 gcagttactc ctgcatctga tccaatcaca gtggcatcca attgtgcgta tccaagagaa
     2641 ataaataatt gatcaaatac tcttcgtgaa gcaaaaggac caaatgtatg aagataaggt
     2701 ctaaacccct gaatagacaa gcctgctgca aggccgacca tttctgcttc cataatccca
     2761 acattcacat aacggtctcc aaagtccttt tcaagattat gagtagccat cgaacttgac
     2821 aaatcggctt ctaagactac tatatcagaa taactttgat tagcctctaa aaggaagtct
     2881 ctatatacat gccgtaattc tttcgtactt ctcatcattc tgtttcctcc aattcctgac
     2941 ttaatctttc tacaactgaa gttaacattt gtttctcctc tacagtaagg cgaagatgat
     3001 gattggattt catttcttcc agctcttgaa ccccttgacc tttaatagta tctaatacaa
     3061 tgcacttagg tgatgaatta tttgactgtt ttaattggac aatcccttca taaatttctc
     3121 taatatctga acccttgacc ctaatggatt caaatccaaa tgctgaaaat ttttctacga
     3181 aatcacctgg attacaaata tcctttgtaa aaccatctaa ttgttttttg ttatcatcaa
     3241 caaatacaat taagttggat aactgttgat gagaagcaaa ctgtatagcc tcccaacatt
     3301 gtccctcatt taactcacca tctccaacaa tagcataagt ataaaaggga ctctttctta
     3361 ttctctgacc atatgcaagt ccagttgcaa cactaattcc ttgtcctaaa gagcccgttg
     3421 tcatatctat gcctggcgtt agatttctat caggatgaga cggtaatttg gttccatttg
     3481 tatttaaaga atataggaat tctttgtcaa agaaaccatt caaatagagt gtactgtata
     3541 gagctggtcc tccatgacct tttgataata tgaaataatc tctatctcgt gctgcaaata
     3601 tttctggagt cattggcatt atttcaccat aaagcactgc taaaacttct acgatagaca
     3661 gacttcctcc gtaatgtccg aatccaagat gattcaatgt tctaagagta tttaatcgga
     3721 tgttagtcgc aaattttctt aacccatctt ctctattttt acttaaaatc atcccttatt
     3781 cctcctttgc agatggcttt ttaataaagg atactccaaa cataactgct agaataagaa
     3841 caagaccaat cacaatgcct gcttgtgagc caaattgatt taacattcct aaaataattc
     3901 ctgatagacc aaaatctgca tctgagaaag ttgatccttg gaaaccaagt cctcccaaaa
     3961 ctggcattaa aaagactgga agaaaactga ttaaaatacc ttgtaaaaat gctccaatag
     4021 tggctccacg aacaccacca gatgcattcc caatgacacc tgcagtcgct ccacagaaga
     4081 aatgaggcac aacacctggt aagataacaa ccgttcctga agcaatcata attgccatac
     4141 ttactaaacc accaacaaaa ctagagataa atccaattag aactgcattg ggtgcataag
     4201 tataaacaat cggacaatcc aaagcaggtt ttgaattagg tacaagacgc tctgaaatac
     4261 ctttaaaggc tggaacaatt tcacccaaaa taaggcgaac acctgctaaa ataacaaata
     4321 cccctgctgc aaattgacct gctaattgta aagcataaac tagaccactt gtaccactac
     4381 tgatttcttt ttctatatat tctgaccctg caaagatagc tacaataatg taaataactg
     4441 ccatggataa agtgatacta acagtactat cacgtaaaaa agctaaactc tttggaaatt
     4501 taatgtcctc tgttgatttt gatttgtcac cgataaggct accagtaaaa ccactcaacc
     4561 aatatcccaa agaactgaaa tgacctaaag ctaccttgtc atttccagtt aattgaacca
     4621 tatatttttg cacaaatgct ggggaaatac tcataataat accgagtgct aatcctccta
     4681 gtaagatgag aggcaagcta gtaaagccag caactgataa aatgaccgca atcatacatg
     4741 ccatatatag agtgtggtgc cctgttaaaa aaatatattt aaatcgagta aaacgagcga
     4801 ttaagatatt gaacaccatg cctgcaaaca taatcattgc agtagctgag ccatatgttg
     4861 ttaaagctac agctacaatt gcttcattat tcggcacaac gccagataaa tgaaaagcat
     4921 gctcaaacat ggtaccaaat ggatttaaag aattttgtac aattcctgca ccaccagata
     4981 caactaagaa accaacaaag gtcttaattc cacctttaat aatatcaggt aatttcttct
     5041 tctgaagaac taatcctaag attgcaatta aagctactaa aatagctggt gtactaacaa
     5101 tatccaatat gaacttcatc atgacgctag cctcctatat aagtcctttt tcttcacaaa
     5161 gtttagtaat taattctcgt agttcatcca tatcaataat actatttaag atacgaacat
     5221 ctccaagatg actagctgaa tcagctagat cacgaccaac aatccaaata tcagctgcat
     5281 ttggatctgc tccacctaaa tcataatgtt caacttctac atccgaaaca ttcaaatcac
     5341 tcaatacaga ttcaatattc atctgtacca taaaacttga acctaatcct gaaccacaag
     5401 ctgtaccaat ttttaacatt atctaatcct cctgtttaat tatcatttta atgtcatcat
     5461 agttttttga tgatattaaa gtttgaacat gatttttatc tcttaaaatt gttgttaaat
     5521 gtgacaaagc ctttaaatga ctctcattat caatggctgc aatacaaatc aacaatctta
     5581 cctcttgttc tggattatcc aataaataaa tcggttcttc caaaactaac attgacattc
     5641 ctatttcatt cacaccttca tctggccgag cgtgaggaat tgctactccc ttccctaaat
     5701 taataaaagg cccaaactct tctacttttt gaatcattgc ctcagggtag ttctcagtta
     5761 tcttatcttg atccaaaagc ggtttagctg ctaaacgaat cgcctccttc catcctaatt
     5821 tttgcgaact aacctgatag gtttctttgg taataagttg ttctagcact ggtacaattt
     5881 cctttctatc atttttttga taaagataat tctttaacgc caatcttaat tccaattctt
     5941 gtgtaataat tccatatctt ttgacaatat tcaggatttg ttcaatctca aaatccccat
     6001 actctaaatt cggaaaatct tttaacacta gttctactag ttgtattgct tgctcttcag
     6061 tcatcataac cgaaactaga taatttggct tttctgtctc cacctttatg gtagaaaaaa
     6121 ccatatcata gtcactacta gctttcacct gtaaatcatc aatctttgag gttcctataa
     6181 actcaatttg aggaaataat gctaatagat tctcttttaa catcaatgaa gaactaacac
     6241 cattaggaca aatgattgct gctttatacc atttttgagg caaagtatct gctttcttta
     6301 aataacctcc gaaatggata acaaaatatg ctgtttcact atcaggtatg ggattgtcaa
     6361 tagcgtccat caagggcatc aaagaatctt tgactaattc aaataaatca ggataatgtt
     6421 ctttaacatg caatacatat tcatttgaac taggtaggcc gaactttaat ctatagtaag
     6481 ccggtataag gtggcgacga agattttctc tcaatccttc cctttgttta aaatgtaaca
     6541 aagaaatatc ttccattcta cttataatag cctctgttaa ttgattaaag taaaccggag
     6601 caacatctac ttcaccttca aagcaacttg ataataaaac tgtgatatag cgataatcat
     6661 cctcagaaaa caccgtatct ataattccca aatcaaccac tgtatccaat aaaatagtcg
     6721 ttatatcttg aataacagga gatactaatg tctctgaaag acatactctt tcaacatccc
     6781 tttgatacct acacagaatg aatactaaac cgaaaaggta aacttttaat tgattaacaa
     6841 taggtactag ctgtagcttc tcataataat ctttaactac ctgatcaatc aaatcataag
     6901 ttaatgaata cccccaactg gataaaacat aatccaaacc ccaaatccct atggaggatt
     6961 ccagcaactc actaaccatt tgaaaagcta agcggtgctt attccactct gaaccgtgta
     7021 aagtataacc ttttgctcta ctgtacccta gctccaaatc attatctaac ataatctttc
     7081 ttaatgattg aatatcagat aaggttgtat tcttacttac tttcaaaaag tcttggtaat
     7141 gattattcga tataaaatct aatcggcaaa aagtgtaaag atagattaaa gctaagcgag
     7201 tcgactttgg taaaaccaat tcatccgact taataatatc tgtcaaagac tgcttcgtac
     7261 gatttgataa actatagcga ccttgctttt tatccagcac tatcccttta ttagctaaat
     7321 aaggcactaa ataatctatt ccttctttga cttcctttat aggtaagctc accttaacag
     7381 ataactcata taatgatagc tcacaatgat ccatcaaagt catcaaaata actagtgctc
     7441 tataatcaaa catttctctt cctttctaac tacaattata gtgtaaaagt tataagaata
     7501 aaagagtatt tgagcacaat ataatctcac cttttaaaag aaattattgg gctgaaagtt
     7561 tttagtgatt atttttcaac tttctattga cttttaaaaa caaagtgata tcatttagat
     7621 atcaaataat gggaggtcat tcttatgact gaaaaactaa tcaattcaaa accaaatggt
     7681 gtattcgcat tgattctcat tgaattgacg ctcgtacttg gtatctttat atttataatg
     7741 ggtgttggtt cggaaaacat ttttggaatt attatcggac ctttactaat cgtaattgca
     7801 ggtctagctc atgctggttt aaaagttgtc aaacctcagg aagctctggt tctgacactc
     7861 tttggtaatt atacaggtac catcaaagaa cctggttttt actttgtcaa tcccttcagc
     7921 gtagcagtca accctgcaaa ccacactcga cttggacaaa gtggtgatgt tagcacaaaa
     7981 tctccttttt taggtgctaa atcatcaaat gacaatgatg taaatcttga aattggcaag
     8041 aaacacattt ccctcaaagt catgaccttg agcaattctc gtcaaaaaat caatgattgc
     8101 ttaggaaacc ctgtagaaat cggtatcgcg gtaacttgga gagttgtcga taccgctaag
     8161 gcagtcttca acgttgataa ctacaaagaa tatctttcat tgcaatgtga tagcgccctc
     8221 cgtaatattg tccgcatcta tccttacgat gtgtctccta atgtggatac tacgggtgac
     8281 gggcaagcag atgaaggtag tctccgtggc tctagcgaaa ttgttgctaa ccgtattcgt
     8341 gaagaaatcc aaaatcgtgt tgaggatgct ggcttggaaa tccttgaagc acgtatcact
     8401 tacctagctt atgctccaga aattgctgcc gttatgcttc aacgccaaca agcatctgcc
     8461 attattgatg cacggaagat gattgtagat ggtgctgtag gaatggttga aatggcacta
     8521 gaacggctca atgaagggga attggtagaa cttgacgaag aacgaaaagc tgccatggtt
     8581 tcaaatctcc ttgtcgttct ttgtggcaat catgatgcac aaccaattgt caacacagga
     8641 agtctttact aaagatggct gaagctaaaa aaaagcagat cccccttcga ctctcaacaa
     8701 agttatacgc tgcactcgca tcatgggcag aagacgactt tcgttcagtc aatgggcaaa
     8761 tcgaatatct cctcacagag tgtgtcaagc aacggaagaa agacggaaaa tacgtatcag
     8821 aaaccattga cgaaccattt gagattgata tttaacacct tctcctgtct gccgtgtcgg
     8881 ataggagaat tttttcatct ttttttgtca agtaacttta ctttacaaaa aaaatgtgtt
     8941 atcctagtat ggttgatgaa aatcagtaga ttgaatcgaa tataaatacc taaaggagaa
     9001 atcaaaatgg cagtacctgc acgtcgcact tcaaaagcga agaaaaacaa acgtcgtaca
     9061 cactacaaag taacagctcc atctgtaaac tttgacgaaa ctactggaga ttactcacgt
     9121 tctcaccgtg tatcacttaa aggatactac aaaggacgta aaatcgctaa agctgcatca
     9181 gctgaataat agaagggaga taccatgcgc gtaaatatta cacttgaaca caaagaatct
     9241 ggtgaacgct tgtaccttac ttctaaaaac aaacgtaaca ctccagaccg ccttcaattg
     9301 aagaaatact caccaaaact tcgcaaacac gttgtgttta cagaagtgaa gtaagcattc
     9361 aatacgaatc aatacagaag aaaaacgctt gatcagcgtt ttttcttttt gttaatttca
     9421 ctatattgca agagaaatca ttcgaatgac tacatttttt gaaataagaa tacggattcg
     9481 gacaattaaa agcaagagga actcaaatgt aagttggggt tccttttttg tatatttttc
     9541 aaataacgcc tctacactat ttgtagcaaa ttcaccaact acagttgtat cttagttaaa
     9601 ataagttaga atatgtaagt gagtaccaga tataccaaga catcgtcacc atctaaggta
     9661 tattcaaaat acaaaagttg accaactaga tttctgaata tccttatata tccattctta
     9721 aaattggttt aaatagcgta gtcttttaaa ctagttttaa gaatccaaaa aatcttccta
     9781 catatgtaag aagatttttt agttcagaat gattagattt agctaatgga tacctatcct
     9841 acccactcac cgttagcatt gactcgatag ccatcgggtg tagtcgtgtt tactaataaa
     9901 tctcctgaat tataggtata gtaccattta ccagaaactg taaaccaacc agtagccatt
     9961 gaacctgatt catttaagta ataccataag cctttgtctt taacccaacc agtagccatt
    10021 gaacctgatt c
//
LOCUS       DAVMJI010000049        10030 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.050, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000049 DAVMJI010000000
VERSION     DAVMJI010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.050"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            101..265
                     /locus_tag="VYR58_001862"
     CDS             101..265
                     /locus_tag="VYR58_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV3622963.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            349..915
                     /gene="amaP"
                     /locus_tag="VYR58_001863"
     CDS             349..915
                     /gene="amaP"
                     /locus_tag="VYR58_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV3622964.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            927..1097
                     /locus_tag="VYR58_001864"
     CDS             927..1097
                     /locus_tag="VYR58_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV3622965.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1136..1744
                     /locus_tag="VYR58_001865"
     CDS             1136..1744
                     /locus_tag="VYR58_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV3622966.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1775..1978
                     /locus_tag="VYR58_001866"
     CDS             1775..1978
                     /locus_tag="VYR58_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV3622967.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLHKEEK"
     gene            complement(2184..2630)
                     /locus_tag="VYR58_001867"
     CDS             complement(2184..2630)
                     /locus_tag="VYR58_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3622968.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFPLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLDSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYIMKKGR"
     gene            2700..3359
                     /locus_tag="VYR58_001868"
     CDS             2700..3359
                     /locus_tag="VYR58_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV3622969.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQIFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFRLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(3331..4107)
                     /locus_tag="VYR58_001869"
     CDS             complement(3331..4107)
                     /locus_tag="VYR58_001869"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV3622970.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(4100..5323)
                     /gene="trpB"
                     /locus_tag="VYR58_001870"
     CDS             complement(4100..5323)
                     /gene="trpB"
                     /locus_tag="VYR58_001870"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV3622971.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(5301..5900)
                     /locus_tag="VYR58_001871"
     CDS             complement(5301..5900)
                     /locus_tag="VYR58_001871"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV3622972.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCVSIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQTFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPHAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(5887..6654)
                     /gene="trpC"
                     /locus_tag="VYR58_001872"
     CDS             complement(5887..6654)
                     /gene="trpC"
                     /locus_tag="VYR58_001872"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV3622973.1"
                     /translation="MSQEFLARILEQKVREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKKLYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(6651..7655)
                     /gene="trpD"
                     /locus_tag="VYR58_001873"
     CDS             complement(6651..7655)
                     /gene="trpD"
                     /locus_tag="VYR58_001873"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV3622974.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(7666..8232)
                     /locus_tag="VYR58_001874"
     CDS             complement(7666..8232)
                     /locus_tag="VYR58_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV3622975.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(8229..9590)
                     /gene="trpE"
                     /locus_tag="VYR58_001875"
     CDS             complement(8229..9590)
                     /gene="trpE"
                     /locus_tag="VYR58_001875"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV3622976.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
BASE COUNT         2771 a         2266 c         2003 g         2990 t
ORIGIN      
        1 gatattaaaa taaaaaagga gggtaggcag tgttgtgatc aattattgct ggaggtctta
       61 ttggtctctt ggcaggtaaa atcactaaaa aagtagttct atgggaatca tcgcaaatgt
      121 attcgctggt ttagtcgggg catatgcagg acaatctctt ttaggtagtt ggggtccatc
      181 aatcgctgga atggctttgc tcccatctat tgtaggtgca gcgattgtga ttactgtagt
      241 gtcattcttt acaggtagaa agtaaacttt tcgccagtaa agttagcaaa ctatttttaa
      301 atcaatgacg ggaaaaatag tttaaatgtt aaatcgaaag gattgtatat gtcaaaagca
      361 aagaaaatat gtttcattat tttctgtatt ttaatcttga caattttcct tcctgttttg
      421 atagattatc atcaagttag tgatctaggt attcatctac ttagctggag acagaactcc
      481 gtagttgaat tctatcttgc tagatatgtc ttttggggga cagtggttct atcaacttta
      541 gttttattat ccattttagt tgtgatgttt tatcctaaac gttacttgga aatccaactt
      601 gaaactaaaa acgatacatt aaaattaaag aattcggcaa tcgaaggttt tgttagaagt
      661 ttggtgagtg atcatagatt gatcaagaac ccaactgttc atgtaaattt acgaaaaaat
      721 aaatgtttcg ttcatgtaga aggtaaaatt cttccttcag acaacatcgc tgacagatgc
      781 caaataattc aaaatgaaat aactaatgga ttgaagcagt tttttggtat tgagcgtcaa
      841 gtaaaacttg aagttgcagt aaaaaattac caaccaaaac ctcaaaacaa aaagactgtt
      901 agtcgtgtga agtaaggaag taaaaaatgg aatggcttaa acaatatcga tatccaatta
      961 tcgctggtct cataggcgta tttctggctt gtttgattgt ctcctttggc ttcttcaaaa
     1021 caatatttgt attgatttta ggagcactgg gagttgcagc tggattatat atcgaaaaaa
     1081 actatataga taaataaaaa aataaaaatt actaatttaa ttaaaggagt ttcatatgtc
     1141 aaacgaaaaa aatacaaaca ctaacgtaga aaagaaagat gctactgttg tagctcacga
     1201 aatcaaaggg gaacttactt acgaagataa agttatccaa aaaatcattg gtctttcact
     1261 agaaaacgtt tcaggtcttt tgggaatcga tggtggtttc ttctcaaatc ttaaagaaaa
     1321 aatcgttaac agcgatgacg taacaagtgg tgttaacgta gaagttggta aaacacaagt
     1381 tgcagttgac ttaaacgtta ttgttgagta ccaaaaaaat gttccagctt tatattcaga
     1441 aatcagagaa atcgtatctt cagaagttgc taaaatgact gacttggaaa ttgttgaaat
     1501 caacgtaaac gttgtcgaca tcaaaactaa agaacagcat gaagcagact cagtaagcct
     1561 tcaagatcgc gtatctgacg ttgctgaatc aacaggagaa ttcacttcag aacaattcga
     1621 aaaagctaaa tctggtcttg gatctggttt ctcaactgtt caagaaaaag ttagcgaagg
     1681 tgtagaagct gttaaaggtg cagcaaatgg tgtagtatct cacgaaaaca ctcgtgtaaa
     1741 ctaagataaa ataaatataa caggagaaat tatcatgtca gtagaagaaa aattaaatca
     1801 agctaaaggt tctattaaag aaggtgttgg gaaagccatc ggtgatgaaa aaatggaaaa
     1861 agaaggagca gctgaaaaag ttgtttctaa agtaaaagaa gttgccgaag acgctaaaga
     1921 cgctgtagaa ggtgctgtag aaggtgttaa aaacatgctt cataaagaag agaaataaga
     1981 tttagacttt atatattctt ttaagaccaa aaaagagaac gttattgaac tgcatcccaa
     2041 aagttagatt tttctatcta acttttgggg gttgcggtca gtacaatagc gggtgatttt
     2101 ttgcctcgca tctaacagag cgagacagac tgaaagtcat ataacaatca ggaaaagcct
     2161 tggaatcaag gcttttttga tgtttatctc ccctttttca tgatatattt tcgtacaggt
     2221 gcttcaacca tttgaacgat ttcaaatcct tctttttggt aaagattctg agctctttga
     2281 tttgcctcga agacatttag agaaatacta tctatatctt cattttcaaa ggccaaacta
     2341 acaaatttcc ttaaagcctg gctatctaag ccttgcccct gtttctgggg gttgataaaa
     2401 aatctcccga tatgaagatt gctgtcttct agcctgattt tctggataag tcccacaaac
     2461 tcttgttcat caaagattga aaagactcct tccaaggctt gaagggtcag tggaaaagga
     2521 atccttggtc ccatccattg ttcttgaaag actttgccta aggagttgga ccattggcat
     2581 acgagctgag cgttttctat actcaccttt tcttcaaaac gaattgtcat cttttcctca
     2641 ccatcttatc tatgtttctc cattatacta tttctcccat tttttacgaa tagataagta
     2701 tgattgattt ttattttttt ctcgtcggga gcattctagc ttcctttctt ggtttggtca
     2761 ttgaccgttt tccagagcaa tccattatca gttcagccag tcactgcgat tcctgtcaga
     2821 ctcccttgcg tcccttagat ttgattccga ttctctcaca gatcttcaat cgctttcgct
     2881 gtcgctactg caaagttcgc tatcctgtct ggtatgccct ctttgaacta ggcttaggac
     2941 tcctctttct gctttactct tgggaattgc tttccttggg gcaagtcgtc ctaatcaccg
     3001 ctggtttgac cttgggtata tacgactttc accatcagga atatccctta ctggtctgga
     3061 tgactttcca cctaatccta atagcttcct ctggctggaa tctggtcatg gtctccttcc
     3121 tcatacttgg aattttggct cattttattg atatccgcat gggtgcaggg gatttcctct
     3181 ttttagcttc ttgtgctctc gtctttagcg taacggagtt actgatcttg attcagttcg
     3241 cttctgcgac gggtatcctg gcctttcgcc tgcaaaagaa aaaggaaaga cttcctttcg
     3301 tgcctttcct cttacttgct acttgtttga ttatttttgg taagctactg cttgtctgat
     3361 aaaatcctga atcggctctc cttggtggag agcttttact atttttgaac cgacgataac
     3421 accatctgac accgcattga agcgttccag atcggcttga ctagatacac caaaacctgt
     3481 caagactggg atgtcggcca cttgatgaag ttgcgccaag tgcttgtcca aatctgcacg
     3541 gtaattgcct gatttccctg tcaccccatt gatggcaacg gcatagacga atccctccgc
     3601 gccttcaatc aactctttct ggcgctcaat tcctgtggtc aagcttacta aaggaatcaa
     3661 ggcgatatct gtatctgcca aaaatggttc tacaaagttg gcatgttcat gaggcaagtc
     3721 tgggataatc aagcccttca cagctgtatc agccagatct ttgacaaagt tctccacacc
     3781 gtactgaaag agggggttga agtaggtcat gatgaccagt ggaatctctg tttcaatggt
     3841 tttcaaggtt tcaactaaag cctgggtaga ggtcccgtgg gctaaactgc gcaagccagc
     3901 ttcttcgata acaggtccat ctgcaacagg gtctgaaaag ggaataccca cttcaattgc
     3961 agagacaccc aaatcttcta gaaagtggat tgtttctcct agtccatcca aacctttctc
     4021 gtggtctcca gccatgatat agggaacaaa aattcctttt ccagctgctt taatagcatt
     4081 taattttttt gttagtgtct taggcatgag cttctccctt ctttgctgca tctgcttcca
     4141 agcggtcttt gacttgaacc acatccttgt ccccacgacc tgataggcat acaatcatag
     4201 acttttctgg tccaagttct ttggccaatt tcaccgcaaa ggcgatagca tggctagatt
     4261 ccaaagctgg gataatccct tccacacgag acaagagttg gaatccttcc aaggcttctt
     4321 cgtctgtcac agggacatag ctggcacgtt taatatcgtg gtagtgagaa tgctctggac
     4381 cgataccagg atagtccaaa cctgctgaga tagagaaggc ttcaagaatt tgaccatggg
     4441 catcttggag cacatccatg agggaaccgt gaaggacacc tggacgaccc ttggtcaagg
     4501 tagctgcgtg gtgctccgta tccacaccaa atccagccgc ttcagctcca tacatggcta
     4561 ctgactcatc ttctacaaag ggatggaaga gaccgatggc attcgaccca ccaccaacac
     4621 aggctactag ggcatctggc agattttgtc ctgtcaagtc acggtactgt tgtttagcct
     4681 ctcgaccaat gacactttgg aagtcacgaa caatttctgg aaatggatga ggccccaagg
     4741 cagaaccaag gatatagtgg gtatcatcta tattagccac ccatgaacga agggctgcat
     4801 tgaccgcatc cttgagcacg cgcgaaccat ctgtcacggc ctcgacctta gctcccaaaa
     4861 gctccatacg gaagacattg agggcttggc gtttgacatc ttcctcaccc atgtagatgg
     4921 tacattccat gttaaagagg gccgcagcag ttgcagttgc cacaccgtgc tgaccagcac
     4981 cagtttctgc gataattttc tttttaccca tgcgtttggc aagccaaact tgtcccaagg
     5041 cattgttaat cttgtgggct cctgtatggt taaggtcttc ccgtttgaga taaatcttgg
     5101 ctccgccgat atgctgggtc aagttttttg cgtaataaag aggagtttca cgtcctacgt
     5161 actggcgcaa aagctggttt aattcctctt ggaaacttgg gtctgcctga ctttcacggt
     5221 aggccttctc caactccaaa actgctgtca tcaatgtttc tgggacaaaa cgtccgccga
     5281 attttccgta aaatccatct ttatttggtt cctgatatgc catgctttac cctctctata
     5341 aatcttctaa tcttttcatg atctttttgt ccatctgtct ccactccgct cgatacatct
     5401 actgcatggg gagtaaaatg ttgaattgct tttactacat tatcttcatt aaggccacct
     5461 gcgataaaga agggctgtgc tagtccagtc gtatccagtt gaccccagtc aaaggtctgg
     5521 ccactccctg ccactggggc atcaaagagt agatagtctg cctgagaatt ggggacatgc
     5581 ccatttccat ctacctgcac agcctgaata ctgacacaag gcaaattctc aaataaatca
     5641 gctgccacct gaccgtgaac ttgaaccaag tccaagccaa ctttgtcaat cgcttccagc
     5701 agttctaccc gacttggtga aacaaatact ccaacctttt tcacatctgc aggaataagc
     5761 tttgccaact cagctgcctc ttctaaagtc acctgtcttt tactaggtgc aaagacaaaa
     5821 ccgatatagt cggctcctgc tgaaacggct gtttccaccg cttctttggt cgatagtcca
     5881 caaattttaa cctttgtcaa tctgcaactc cttgattctc tgggccacat tttctgcctg
     5941 cataagagct gttcctacca aaattccgtt aaagtatggg gctagtcgtt ccgcatcctg
     6001 ccctgtgaaa atggcagatt cagaaatgta atagcgacct tcctcaaagt aaggggctaa
     6061 atctacactg gtctgcaagt cgacctcaaa ggtagtcaag ttgcggttgt tgaccccgat
     6121 aatctcagca ccaagtctgt gggctacctc tagttcagct agattgtgag tctccactaa
     6181 gacttccaga ccaagctctg tcgcgtagtc atacagtttc ttgaggcgtt cttcggacaa
     6241 ggctgccaca ataagcaaga taactgtcgc acctgcattg cgagcgcgga tgatttgctt
     6301 ttcatcgatg ataaagtcct tgttgagcgt cggaatctct acctgactgg aaatttcccg
     6361 tagataatcc aaatgccctt taaagaaaac ctcatctgtc aacaccgaaa tcatcactgc
     6421 tccgttttct tcataagtct gggcctgttg cacaatatcc acatcgagat tgatatctcc
     6481 caaactaggg ctagctttct tgacctcagc gattacctgc aagcggtcct gatgattctt
     6541 caaaaattct gccaagcgat aggtctggcg cagaggctgg atttgctcca gcttcatctg
     6601 ctccacctca cgcaccttct gctctaagat tcgtgctaaa aattcctgac tcatttttgg
     6661 tactcctgta acagtctgag tttttcaagg gccttgcctc tagcaatcac ttgacgggcc
     6721 aaggcaactc cttccttgat gctatcaatc ttaccattag catagaaacc aagaccagca
     6781 ttcaagactg tcgtttccaa gaatggactt gcttcgtttt tcagaacgct aagcaaaatt
     6841 tctgcatttt cctgagcatt cccaccacga atatcttcca tagcatagcc ttccattccc
     6901 aaatcctctg gagtaaagct tgacaagctg atttcgccat tttcaagaag tgcaatcttg
     6961 gttgttccgt tcaagccagc ttcatccaac ccttctggtc cagcaaccac gatggcacgt
     7021 ttgcgaccca tatttttcaa aacctgagct gtactttcta ggagttctgg acgactaatt
     7081 ccaagaagct gtgtttctaa agccattgga tgaatcagtg gaccagtcaa gttcataatc
     7141 gttggaattc ccaattccaa acgagctggc atgatgtatt tcatagctgg gtgcatattt
     7201 ttagcgaaga gaaagacgat tccagtttta tcaaagacct tacctagttc agctggtttg
     7261 aggtcaagat tgattcccaa ggcttcgagg acatctgcgg agccagattt agaagaaatc
     7321 gagcggttac catgcttggc catgtgaata ccgccaccag ccaagacaaa ggctgcagtt
     7381 gtggaaatat taaaactgaa agacttgtcc ccacctgtac cacagttgtc catggcatca
     7441 tgaatctcag ttggaatatg ctgggcatgt cctctcatga cttgggcaat ggctgtgcgt
     7501 tcttcaggtg tttccccctt catcttaaga gctaagagga gagaagcaat ctgcgcttca
     7561 gttacacgcc cagttacgat acgctcaatg acatccgtca tttccacacc tgataaattt
     7621 tcaaattttg ctagtttttc aataatctct ttcatcctag tttcctcact ttacaacctt
     7681 ctcgataaaa ttccgaatag aagacaagcc gtctggcgtt ccaatgctct ctggatggta
     7741 ctggaagcca taaatcggta ggtttttatg ttgaatcccc atgatggctt ggtcatcagt
     7801 cgaacgagct gtcacttcaa agtcttctgg catttcctca atcaaaatac tgtgataacg
     7861 catgaccgca cgtccatcct caataccttg atacaaaaca gatggcgctt caaagttgat
     7921 attgctctgt ttcccatgca tgacttttgg agccaaacct agcttaccac caaagacttc
     7981 tgcaatggct tggtgaccca aacaaatccc tagaatcggc ttcttgcctg caaaatcaca
     8041 aatcatgtct tccatctttc cagcatcaac tggccaacca ggaccaggag aaaagaccag
     8101 accatctgct ttttcagctt cttcatacag cttggaatca tcatttctca gaacctgaac
     8161 ttctgcaaaa ttcccaatgt attgggccaa gttataggta aaagaatcat agttgtcaat
     8221 caataaaatc atggtcttag ttctccaatt ctagtcatag attttgcttt gttaatggtt
     8281 tcttggtatt cgttttgggc gatagagtcg tagacaatcc ctgccccagc ctgcacatag
     8341 gctctttgat ttttgagaat catggttcgg atggcaatgg ccaaatccat atcacccgtc
     8401 gcagacaagt agccgattgc tcctgcatat acgccccgtt tttccgtttc cagttcatag
     8461 atgcgtctca tcgctcgaat ttttggtgct ccagaaacgg ttccagcagg aagcgttgct
     8521 ttcaaggcat ccatggcagt gagttctgca agcaaacgtc ccttgaccac actggtcaaa
     8581 tgcatgacgt agcggaagag ctccacctcc atatacttag taacttggac actggccgtt
     8641 tcagagatgc ggccaatatc gttacgcccc aggtctacta acattcgatg ctctgctgtt
     8701 tccttctcat cagagaggag gtcagtcgcc aaggccttgt cttcttcatc cgtagcccct
     8761 cttggtcgcg tccctgcaat cggattggtt gtcacgatgc catttttgac agaaaccaaa
     8821 ctttctggac tggctccgat gatttgataa tccccaaaat catagaaata aaggtaatta
     8881 gaaggattag tcacgcggag atttctgtag aagtcaaatg gatttccagt aacttctgct
     8941 gagaaacgct ggctgagtac acattggaac atatctccgt tacgaatcaa gtcacgagct
     9001 gtttctacca ttccctcaaa cttatgtgga gcgatatgcg gtttgaagtc aagtggtgat
     9061 aaatccaagt cttcaaattc atttggagca ggaatgcgta attcctcaag cacttggttc
     9121 aaggattttt ccaaggcctc ttgactgcgc tcactataaa gtgcatcctc tatgacatgt
     9181 atcttctcct tcttgtggtc aaagaccata tagctctcat agacaaagaa atgcatgtct
     9241 ggcgtcccaa ttgtatcctc agggatttga ccaatttctt cataaagcga aatcatatcg
     9301 taaccaacaa aaccaatggc tcccccacca aaagggaggt ctgaatggtg ctggctctta
     9361 tgagtcactt cataaaggaa atccaaggga tcccgatcaa tcgcttgacc attttgataa
     9421 agaactccat tttcaaactt aatctcaaaa acaggattat aggctaggat agaaaaacga
     9481 gctgtttcct tgtctctcgg aatactctct aagataacct tgtgttgccc ctttaggcgc
     9541 atataagcca agattggtga taagacatct ccatgaatga ttcgttccat tgtaatttcc
     9601 ctttcagttc tacttctagt ccgtggtgac tgtatgaaaa atccccacgc aaaataactt
     9661 gcgtgaggac gaaattcgcg gtgccacctc aattatagga tttctcctat ctctcattcc
     9721 tgtctcagat atctcctgta acaggctgtg cgataaaggg cactcccttg agaatgatgt
     9781 tttcttctct cgtttcagat gaacccaact ttacagcttt ctctgcttgt tttcagcaac
     9841 cacaagctct ctgtgagaga aagaactgta atttttccat ctattatttt ttagcttcta
     9901 gtagtctgca atcgcagcta ggtccttgcc tccacgacca gagacattga tgaagagatg
     9961 ttcatctcgg tacaccttta tactcttcga aaaactcttc aaaccgcgtc aacgtcgcct
    10021 tatcgtaggt
//
LOCUS       DAVMJI010000050         9017 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.051, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000050 DAVMJI010000000
VERSION     DAVMJI010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.051"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            78..560
                     /locus_tag="VYR58_001876"
     CDS             78..560
                     /locus_tag="VYR58_001876"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622977.1"
                     /translation="MSTLILGELLSSLIISRKKQETSPLKNGYSIMLGSTLAMSFLGF
                     STFFSNKPIAFSFILLSLFSMTFIESFFTIPLQVWYVTEIPEKIQGRIFAFLGAIISF
                     FSPLSTLMFSGLYEIKTLPLQQINAIIIFSAVSIRLISTIYLKFIKKVNLADAHVLKY
                     "
     gene            776..918
                     /locus_tag="VYR58_001877"
                     /pseudo
     CDS             776..918
                     /locus_tag="VYR58_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            1117..1527
                     /locus_tag="VYR58_001878"
     CDS             1117..1527
                     /locus_tag="VYR58_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HEV3622978.1"
                     /translation="MEAIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEVEE
                     GTNPLEKDLQDIDQTSITEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENQQD
                     LEDLYTYYMRTDSVSLLSSDLETSPQEVEMEIEL"
     gene            1575..7799
                     /locus_tag="VYR58_001879"
     CDS             1575..7799
                     /locus_tag="VYR58_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV3622979.1"
                     /translation="MEVMQLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVENFL
                     TEEGKIEEIPHVYSFDQDIVSFLEASSENNDQDLESYTRSFGQAGLGKLSQLSNFEKN
                     LVLEVAIYNLSTRFYIQSEKEKLTPLSELVCHQNQDVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKEVKKEVLEIHFEGKEGDVLAYLGSELMATLDSVTELVHHEENYQQLPLT
                     QKLKIITHFDDVKAKIEKSKRVAEVVLPLDNIEQVEENVEVHSLSKVDKIVEEALREY
                     PIGSQVSYRGQVFQLVSIENAQLNDLVRLELFNDSNQLFEENPILYLNSLEEIEQVLS
                     LVELEKEDSEIEIESPSESQEIDLFSYLEEENEKDKDKETKPLISGIEETEVPVQDFV
                     FPDDLEDFYPKTNREKIETNIAAIELVKRLEKEGRQANPEEQELLAKYVGWGGLANEF
                     FDELNPKYETERLTLRSLVSKSEYSTMKQSSLTAYYTDPMIIRQIWQKLLDDGFGGGR
                     ILDPSMGTGNFFAAMPRSIRDKSELYGVELDSVTGAIAKQLHPNVHIEVRGFEEVPYQ
                     NNSFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTMDK
                     RTDNVLQEIKSNTHFLGGVRLPDTAFKKIAGTRVTTDLLFFQKDQAKNLNEEELVFSG
                     SIPFEEDKRVWINPYFDGKYNTQVLGKYEVRNFNGGTLNVKGGSETLATDIMKALENV
                     EEPKPIDNSLKAPVFIQEEVDNSIPSRIREDLALYSFGYEGNQIYYRDTHGIRKSSKV
                     DEISYYVDEKGDFKAWDSSLSEHKIDRFVKLHLTDEEALDVYKSEEASKRGKYKGLFK
                     KTVFYENPLSDKDISRIKGMVDLRETYQSLIEIQRHQDYSRTDFQVLLSKLNHDYDRF
                     VSQFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPERV
                     ITRVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQAAILDELGDQVLMDPESYLRGER
                     KYLSKNQFLSGDILNKIEVVQLLVEENNQEYDWNHALDLLESVRPPRIHLADIEFKIG
                     SRWIPQSVYGKFAFECFTNREFELSSPDVEQVIEVNPVDGQVHLRTSFAYRYPSAKDS
                     SLGVSGSRYDTGRKIFENLLNSNQPTITMTFTEGEKKKTITDLEKTSVLRAKEQHLQE
                     LFQEFVSRYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAIQR
                     IVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKFFP
                     TKKVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDKLN
                     ELREIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEAHH
                     FKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSISEL
                     YTMMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLPEL
                     MKIYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDMVKCGTVDPS
                     QDNMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMENKATQMIFS
                     DIGTPKKKDNGFDVYSEIKALLVDRGIPSKEIAFVHDANSDEKKNSLSRKVNAGEVRI
                     LLASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYITK
                     GSFDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKYKM
                     ELENDLTLLENQRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEMSKDQA
                     FSMTVGKQAFEQRAEAGESLHRLIRHNQSDSKEFRTLASYRGFDIKMLSLPTNQPLPE
                     TFSVKIVGENQYSVSLDLYSPLGTIQRLQHTIDHIKEDQVKTQNLLDELQDKLTTAKV
                     EIEKNFPKEEDYQTKKAEYDVLAPLIETETDLDIIDQALRQFHEKGKEKQEQLSFELD
                     "
     gene            7874..8158
                     /locus_tag="VYR58_001880"
     CDS             7874..8158
                     /locus_tag="VYR58_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622980.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSK
                     RELTSQLEIALQNHRGVDFEDYEKEDYLELVQKLEEFDSSLATHYRQLID"
     gene            8172..8492
                     /locus_tag="VYR58_001881"
     CDS             8172..8492
                     /locus_tag="VYR58_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622981.1"
                     /translation="MNDLLLIPVIFLAVGGILILLWRIFLIASGLFLIGFVSFLIFVE
                     VYGIYLFFTETELYTEDLAQNGLFGFTTFFIIFNLTLLVLAGWAGYKRKRHNNVLANQ
                     RDFW"
BASE COUNT         3071 a         1428 c         1817 g         2701 t
ORIGIN      
        1 acactgtaat ctatattgct acaccaatta ttatcttaaa tatattggaa ttctcaaata
       61 tatattactc agttgcaatg tcaacactga ttcttggtga attactatcc agcttaatta
      121 tttcacgaaa aaaacaagaa acttcaccat taaaaaatgg ttattccatt atgctaggct
      181 caacgctggc aatgtcattt ttaggattca gcacattttt ttctaataaa cctatagcat
      241 ttagttttat tctgctctct cttttttcta tgacatttat tgaatctttt tttacaatac
      301 ctcttcaagt ttggtatgtg actgaaattc cagaaaagat tcaaggaaga atatttgcct
      361 ttttaggagc tataatttcg ttcttttcac ccctctctac attaatgttt agtggattat
      421 atgaaataaa gacattacct ctgcaacaga tcaatgctat aattattttt tcagcggtct
      481 ctatacgact gatatcaaca atctatttaa agtttattaa aaaggtaaat ttggcggacg
      541 cccatgttct aaaatattag tcagtgatat gtttaaaaaa taaccaatag aagcgtataa
      601 aagtttaaat tcaaaatttt actggcctct ctttttcatg aacacaaatc tcctctaatc
      661 gtctctctga ctttttagga ctgaatcacc ttcaaagacc acgaagacga cttttttgaa
      721 tgtccatctg gttcatcatc ttaggaggtt tatccactat gcttagacgt tttgtaaccc
      781 aaaagcatct cacgctctac tttctagcct agaatcttta aaaatccgaa tcgaactatt
      841 attattgcga cccacaatcc tcttatttgg gaacaagtgg accaagttat tcgagttacc
      901 gatttatcac atagatgata tggcaagatt cagttagaag aaagtttttg attatataca
      961 gcataaattt ctaaaatctg tagtacttgt ttataatcac aatattattt gagaacgcag
     1021 ttttggctcg ttctcttttt ttgttgtgat acttctttca aggaatattt ggtaggattg
     1081 gagtgaaaaa agattaacta ggaaagaagg aagtatatgg aagccattta tcaacgtgat
     1141 tcggatcaag atggactgac tgatgctcaa gaattggcgc taggaaccaa tcctcttagc
     1201 gcagattctg atggtgatgg tcgttcagat ttagtggaag tagaagaagg aaccaatccc
     1261 ttagaaaagg atttacaaga catagaccaa acaagtataa ctgaaccgtc ttcagtattt
     1321 atggaaatga aacaaaagat ttcagatatg atggagagtc actacaagga atttatacag
     1381 gctctgatta gtattgaaac agggattgaa aaccaacaag acctagaaga cttatatact
     1441 tactacatga gaacagattc tgtttctctt ttgtctagtg atttagaaac cagtcctcaa
     1501 gaggttgaaa tggagataga gttgtagggg aatcatgtga ttctcctatt ttcgtataga
     1561 tgaaaggagc gagtatggaa gtaatgcaat tattggctat gtttcgtgga acaattccaa
     1621 aagataggga gaaaatggat ctatttcttc gttatcaagc gcaacatttt gatgagaaat
     1681 ggcaggattt ggtagagaat tttttgactg aagagggcaa gatagaagag attcctcacg
     1741 tctattcttt tgatcaagat attgtttctt tcctagaggc tagttctgaa aataatgacc
     1801 aagatttaga aagttacaca agaagttttg ggcaagcggg tctaggtaaa ttatctcaat
     1861 taagtaattt tgagaaaaac ttggtgctag aagtcgcaat ctataacctt tccactcgat
     1921 tttacataca atctgaaaaa gaaaagctaa caccattaag tgagcttgta tgtcatcaga
     1981 atcaggatgt caatttagtc aatgtctatc gggttgcgaa taatctatct gaccgcatta
     2041 gtagagatat agaggagttt cttctaatgg ttgattccaa agaggttaaa aaagaagttc
     2101 ttgagattca ttttgaagga aaagagggag atgttctagc ctatttgggt tctgaattaa
     2161 tggctacttt agatagtgtt acggaacttg tccatcatga agaaaactac caacaactcc
     2221 cactgacaca aaagctgaag attattactc actttgatga tgtaaaagct aaaatcgaaa
     2281 agtctaagcg agtagcggaa gtggtcttac ctttagataa tattgagcag gtagaagaaa
     2341 atgtggaagt tcattcccta tctaaagtag ataaaattgt agaagaagct ttgagggaat
     2401 atccaatcgg ttcacaagta agttatagag gacaagtatt tcagttggtt tcgattgaaa
     2461 atgcacagtt aaatgactta gttcgcctag agctattcaa tgattccaac cagttatttg
     2521 aagagaatcc tattttatat ttaaacagtt tggaagagat tgaacaagta ttgtctctgg
     2581 tagaacttga aaaagaagat tcagagattg agattgaatc accaagtgaa agccaggaaa
     2641 tagatttgtt ttcctatctg gaagaagaaa atgaaaaaga taaggataag gaaacaaaac
     2701 ctttaatttc aggtatagaa gagacggaag tccccgttca agattttgtt tttccagatg
     2761 atttagagga cttttatcct aagacaaatc gtgaaaaaat tgaaacgaat atcgccgcaa
     2821 ttgaacttgt taaaagatta gaaaaagagg gacgacaagc gaatccagaa gaacaagagc
     2881 tactagccaa gtatgtcggc tggggtggtc ttgccaatga atttttcgat gaactcaatc
     2941 caaagtatga aacagaacgt ttaactctta ggagtttagt aagtaaatca gaatactcca
     3001 ccatgaaaca aagttctctc acggcctatt atacagaccc aatgattatt cgccagattt
     3061 ggcaaaaatt actggatgat ggttttgggg gaggaaggat attagatcct tctatgggga
     3121 ctgggaactt ctttgcggct atgcctagaa gtatacgaga taaatcagaa ctctatgggg
     3181 ttgaattaga cagtgtgaca ggcgcaatcg caaaacaact ccatccaaat gtccatattg
     3241 aagtgcgagg atttgaagaa gttccctatc aaaataatag ttttgattta gtcttaacga
     3301 atgtaccatt tggaaatttt cgcattgccg ataaaaacta tgataaacct tatatgattc
     3361 atgattactt tgtcaaacac tcacttgatt tagtaagaga cggaggacaa gtgtcgatta
     3421 tctcatctat cgggacaatg gataaacgga cagataatgt cttacaagag attaaatcca
     3481 acactcattt tttaggggga gttcggttgc cagatacggc ttttaaaaag attgcaggta
     3541 cccgagtgac tacagatctc ctcttctttc aaaaggacca agcaaagaat cttaatgagg
     3601 aggaacttgt ctttagtggc tctattccct ttgaggagga taagcgtgtc tggatcaatc
     3661 cttattttga tgggaaatac aatacacaag ttttgggtaa atatgaagta cgtaatttta
     3721 atggaggaac cctcaatgtt aaggggggat cagaaacatt agctactgac ataatgaaag
     3781 cattagagaa tgtggaagaa cctaaaccaa ttgataattc tttgaaagca cctgttttta
     3841 tccaagaaga agtggataat tcaatcccaa gtcgtatacg tgaggactta gcgctctatt
     3901 cttttggata tgagggaaat caaatttatt accgagatac gcatggcatt cggaaaagtt
     3961 caaaagtaga cgaaattagt tattatgtag atgagaaggg agattttaaa gcttgggaca
     4021 gttctttgtc tgaacataaa atagatcgat tcgtgaaact tcatttgaca gatgaggaag
     4081 cactagatgt ttacaagtca gaagaagcga gtaaaagagg gaaatataag ggcttgttca
     4141 aaaaaactgt cttttatgaa aatcccttat cggataagga tattagtcgt attaagggca
     4201 tggttgattt gagagagacc tatcaatcct taattgaaat tcaacgtcat caagattata
     4261 gtcggacaga ttttcaggta ttacttagta aactcaatca tgactatgac cgctttgtaa
     4321 gtcaatttgg atacttgaat gcctcagtca atcggaactt atttgatagt gacgataagt
     4381 attctttact agcaagttta gaagatgaat acattgattc taaagatcag aaagtaaaat
     4441 ataaaaaatc tttagccttt gagaaagcat tggttaggcc agagagagtg attacaagag
     4501 tatcaacggc tttagatgcc ttaaactcta gtttatcgga tggtagaggg gttgatttag
     4561 actatatggt atcaatttat cctgaacata gccaagctgc tattttggat gagttaggag
     4621 accaggtttt aatggatcca gaaagctatt taagaggaga aagaaaatat ctttctaaga
     4681 accagttttt atcaggagac attctcaaca agatagaagt agttcaacta ttagtagagg
     4741 aaaacaacca agaatatgat tggaaccatg ctttagattt gttagaatct gttcgccctc
     4801 cacggattca tctggcagat attgagttta aaatagggtc acgttggatt cctcaatctg
     4861 tttatggtaa atttgctttt gaatgtttta ccaatcgtga atttgaattg tcttcgccag
     4921 atgttgaaca agtcattgaa gtgaatcctg tcgatggcca ggttcattta aggacatcat
     4981 ttgcttatcg ctatccaagt gcaaaagata gtagtcttgg agtcagtggg tcacgttatg
     5041 atacaggaag aaagattttt gagaatttac ttaattcgaa ccaaccgacg attaccatga
     5101 cttttacgga aggagaaaag aaaaagacca tcacagattt ggaaaaaacc tctgttctaa
     5161 gagcgaaaga gcagcattta caagaactct ttcaagaatt tgtctcacgg tatcccgaag
     5221 tccaacaagt cattgaggaa agctataatc gtctttataa tcgaacggtt agtcgagagt
     5281 atgatggtag ccatctagtc attgatggct tggcacaaaa catcagtctt cgtcctcacc
     5341 aagagaatgc cattcaaaga atcgtagaag aaaaaagagc cttgttagct catgaggtag
     5401 gttcaggaaa gaccttgacc atgcttggtg ctgggtttaa attaaaggag ttggggatgg
     5461 ttcataagcc cttgtatgtg gtgccttcta gtttgtctgc tcaatttggt caagaaatca
     5521 tgaaattttt ccctactaaa aaggtctttg tgaccactaa gaaagatttt gtgaaggcga
     5581 gaagaaaaca atttgtatca cgtattatta caggagatta cgatgccatt gtcattgggg
     5641 attctcaatt tgaaaaaatc cctgtcagta aagaaagaca gatgaattat attgaggata
     5701 agctcaatga actacgagag attaaaacac attctgaaaa taagtatact gtcaaagaag
     5761 cagaacaatc aataagtggt ctagagaaac aattggaaga actgcaacgc tttaatcgtg
     5821 atagttttat tgattttgag aacttaggaa ttgattttct ctttgtggat gaagcacatc
     5881 actttaaaaa tattcgtccg attacgggac ttggaaatgt agcagggatt accaatacaa
     5941 cctctaagaa gaacgtggat atggaaatga aggttcgaca gattcaggaa gaacatgatt
     6001 ttaagaatat tgtttttgcg acaggaacac ctgtttccaa ttctattagt gagttgtata
     6061 ctatgatgaa ctacattcaa ccggatatct taaaacgcta tcaagttgat tattttgact
     6121 cttgggtagg tgcttttgga gaaattcaaa actctatgga attagctcct acaggggata
     6181 agtaccaacc taagaaacga tttaaaaagt ttgtcaatct acctgagttg atgaaaatct
     6241 ataaagaaac agccgacatt caaacacaag atatgttgga tttacctgtt ccagaagctc
     6301 atattatccc tattgagagt gagttaactg aaaaccagaa actctattta gaagaattag
     6361 ttatgaggtc agatatggtc aaatgtggaa cagttgatcc gagccaggat aacatgttaa
     6421 agataacagg tgaggcacgg aaactagcta ttgatatgcg tttattggac tctagctata
     6481 gtctagcaga caatcataaa ctgcttcagg tagttgataa tgttgaaaga atttatcgtg
     6541 agggaatgga aaataaggct actcagatga ttttttcaga tattggcacc cctaagaaga
     6601 aggataatgg ctttgatgtc tattctgaaa taaaggcttt attagtggat agaggaatcc
     6661 ctagtaagga aattgccttt gtacatgatg ccaatagtga tgaaaagaag aatagcttgt
     6721 ctcgaaaggt caatgcagga gaggtgcgga ttctccttgc ttcaactgaa aaaggaggaa
     6781 caggtttaaa tgttcagagc aagatgaaag cagttcatca tctggatgtc ccgtggagac
     6841 caagtgacat tcagcaacgc aatggccgta ttatccgaca gggaaatgaa aacaaggaag
     6901 tggatattta ccactacatt acaaaaggtt catttgataa ttatctatgg gcaactcagg
     6961 agaacaaact ccgttatatt aagcagatta tgacttctaa ggagccgatt cgtgctgcag
     7021 aagacattga tgaacagact atgacagctt ctgattttaa ggcactagca acaggtaatc
     7081 cttatctcaa atataagatg gaattggaga atgatctaac cctattagaa aatcaaagac
     7141 gcgcctttca acgcagcaag gatcactatc gtcatacaat ctcttactgt gaagaaaata
     7201 tgcccattct tgagaaacga ttaagcaagt atgaaggcga cattcaacag tctgaaatgt
     7261 cgaaagacca ggcattttct atgacggtag gtaagcaagc ttttgagcaa cgagctgaag
     7321 caggtgaatc tctacatcgc ctcatccgtc ataaccaatc tgacagcaaa gaattccgta
     7381 ccctagcaag ctatcgagga tttgacatta aaatgcttag tcttccaaca aaccaacctc
     7441 ttcctgaaac cttctctgtt aagattgtag gagaaaatca gtattctgtc agtttagatt
     7501 tgtattctcc tttggggaca attcaaaggc ttcagcatac gattgatcac attaaagagg
     7561 accaagtgaa aactcagaat ttattggatg aattacagga taaattgact actgctaaag
     7621 ttgaaattga gaaaaatttt ccaaaggaag aggattatca aactaaaaag gccgaatacg
     7681 atgtactcgc gccattgatt gaaacagaaa cggatttaga tattattgat caggccttaa
     7741 gacaattcca cgaaaaagga aaagaaaagc aagaacaact ttcttttgaa ttagattaaa
     7801 aaatagatac aaatagcgga caagaaaaga aaagcgcggt aaaataaaga tagaaagaaa
     7861 cgaggtaacg attatgatgg aagataccta ttatcaatta gaagaggctt tggtacaggg
     7921 atttcaaaca cctgaagaat accaagccta caaggagtta aaggaacatt atgaggaagt
     7981 gacaggggat tacagttttt ccaaacgaga acttactagc caattggaaa tcgctcttca
     8041 gaatcatcga ggtgtggact ttgaagatta tgagaaagag gactatctgg aattggttca
     8101 aaaactagaa gagtttgatt cctctcttgc cacccattat cgtcagttaa ttgattagga
     8161 aggaacaagt catgaatgat ttactcctta tcccagtaat ttttttagca gtaggaggaa
     8221 ttctcattct tttatggagg atcttcctta ttgccagtgg acttttcctt attggttttg
     8281 tcagttttct tattttcgtg gaggtctatg gaatttattt gttctttaca gagaccgaac
     8341 tttacacgga agatttagca cagaatggat tatttggttt tacgactttc tttatcatct
     8401 ttaaccttac tttgcttgtc ctggcaggct gggcagggta taagcggaag aggcataata
     8461 acgttttagc aaatcaacgc gatttttggt gagttcttca ttttcggtat cttcctatct
     8521 attattttta tgcttggtac agtattagtt atctactata aatctctgag gattatgaag
     8581 actgcaaacg ctttatcctc ttgtaaaata taggtctaga tcaaaagcaa atcttgggag
     8641 aatatcctat atccaaaagt tactagatat aaagaattgt tgatgaggat tcgatggtgg
     8701 cgggttaacc aatcactact agctcagctt aactaaaata taaaaaatag tctgggataa
     8761 tattccctta tctccagaaa aagaaactgc aaatccattg ctatttaaca tggttgcgat
     8821 agtcttggta aaatagaatt gcccaataaa ccatttacag atgccgcttt gatgccgata
     8881 aaagaaaacc atatgaagag tggtaaactt aaggctaaaa ctaaaaattt ttgtacttta
     8941 gttaactctt gataaaactg ggttaagtct taatatatac tctttaaaaa atgtacttta
     9001 ttttaaggtc ggataaa
//
LOCUS       DAVMJI010000051         8676 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.052, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000051 DAVMJI010000000
VERSION     DAVMJI010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.052"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..274
                     /locus_tag="VYR58_001882"
     CDS             <1..274
                     /locus_tag="VYR58_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV3622982.1"
                     /translation="VIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELSINMEKKIM
                     NYIFEDDGNVSEVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            287..1762
                     /gene="galT"
                     /locus_tag="VYR58_001883"
     CDS             287..1762
                     /gene="galT"
                     /locus_tag="VYR58_001883"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV3622983.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1775..2785
                     /gene="galE"
                     /locus_tag="VYR58_001884"
     CDS             1775..2785
                     /gene="galE"
                     /locus_tag="VYR58_001884"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV3622984.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIEAAIHFAGYKAVGESVQKPVMYYENNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGVHNHSPLIETMPTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPFIAQVAVGKRPELSVFG
                     DDYDTVDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKVPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            2969..3628
                     /locus_tag="VYR58_001885"
     CDS             2969..3628
                     /locus_tag="VYR58_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV3622985.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRVTEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVRFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3653..4720
                     /locus_tag="VYR58_001886"
     CDS             3653..4720
                     /locus_tag="VYR58_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV3622986.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIPGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSISGLSGGTGRAILASILVRYLDDKGELGVSEKGWEVAKEYLKNAYTL
                     QKGESSIVKMLDKEDPIQYGMMWGSGALVGQKEQNVVFKVMSPEIGVPFVTEQTMILS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4823..5833
                     /locus_tag="VYR58_001887"
     CDS             4823..5833
                     /locus_tag="VYR58_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3622987.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5845..7536
                     /locus_tag="VYR58_001888"
     CDS             5845..7536
                     /locus_tag="VYR58_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV3622988.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7539..8249
                     /locus_tag="VYR58_001889"
     CDS             7539..8249
                     /locus_tag="VYR58_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV3622989.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            8345..>8676
                     /locus_tag="VYR58_001890"
     CDS             8345..>8676
                     /locus_tag="VYR58_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3622990.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVK"
BASE COUNT         2929 a         1191 c         1704 g         2852 t
ORIGIN      
        1 agttatcgga ctgcatatga atagggctat atcttgttat agagaggaac aatctggatg
       61 tttagatatg gttgttatac aaaaacagaa tgagatagaa gagcttagta taaatatgga
      121 aaagaaaata atgaattaca tatttgaaga tgatgggaac gtttctgaag taattagtgc
      181 tttagatatt attcatcacc ttgataaaat tgctcatact acgcaagcaa tttataaatg
      241 gataatgtat agaaaatatg ggaacataaa ttagaaagaa aaatatatga aaacaattat
      301 tgataatttt gttgatagag taattgaata cggaatgtat aatgaaattg acaaaatata
      361 tgtgaaaaat agagtactag cgttaatagg tgaggaggga attgatcgca tttccgatga
      421 aaatgacctg aaacaaataa aagattactt agtggaaatc gccttaaaaa acggtaaaat
      481 taaagattta atcgaggaaa aggaatgttt aggagcagag ttaatgaatt tcatagttcc
      541 tttacctagt cgattaaatg atattttttg gagttcatat gatatatcac ctcaagaagc
      601 agttgaagag ttttataagt taagtaaaga tagtgattat attaaaactt ctgctattgc
      661 taagaatatt gagtttcgag catcaactaa atacggagag ctagagatta cgataaattt
      721 gtcaaaaccc gaaaaagatc caaaaacaat tgctgctgaa aaattagtaa aagcaactaa
      781 ttatcccaaa tgtttactat gtatggaaaa tgaaggatat caggggcgaa taaattatcc
      841 agcacgttcg aatcatagaa ttattcggtt gaaacttggt gacgaagtat ggggattcca
      901 gtattctccc tactcatact ttaatgagca tgcgatattt ttgaatagtc aacatgtacc
      961 aatggctatt acctctaaaa catttgaaca attattggag attgttgata ttttgccagg
     1021 atattttgct ggttcaaatt ctgatcttcc tatctcagga ggctccattc ttagtcataa
     1081 ccactaccag ggagggaaac atattttccc aatggaaaaa gcaaaatttg agagtgaatt
     1141 ttgttttaaa gactttgagg atgttaatgc tggtattgta aaatggccaa tgtcagtaat
     1201 taggttacaa agtgaaaata aaaatcgctt gttagattta gctactaaaa ttctaaataa
     1261 gtggagagaa tattcagatt tagaagtaga catcattgct atgactgaag atgtcccaca
     1321 ccatacggtg actcctattg ctcgtaaagt ggacgggaga tacgaattag atattgttct
     1381 aagagataat catactactg aacaataccc agatggtgtt ttccatcctc atcaagatgt
     1441 acaacatatt aaaaaggaaa atatcgggtt aatcgaagtg atgggacttg cgatattacc
     1501 acctcgtttg aaaccagagt tagaagaagt tggaaaatat cttttaggag aggataatgc
     1561 aattgcggat tatcatttag aatgggccga ccaattgaaa gaaaaatatc ctcgcattaa
     1621 taaagaagag gttaatagcg tagttcaaca cgaagcagga caagtgtttg cgagagttct
     1681 ggaagatgca ggagtttata agaatacacc gtctgggcat gaagcgttta tgagatttgt
     1741 taagtcggtt ggaattaatt aggaggaaac aaaaatggca atattggtaa caggcggagc
     1801 tggttatatt ggtagccata ccgtagtaga attactaaat ttaggaaagg aagtcatcat
     1861 tgtcgacaac ctttcgaact ctagcatctt ggtgctagac cgtattgaag caattacagg
     1921 aatacgtccc gtgttttacg aattagatgt ttgtgataaa ccagcattga gaaaagtttt
     1981 tgaacaagaa tctattgagg ctgcaattca ttttgcagga tacaaagctg tcggcgaatc
     2041 cgtgcaaaag cctgtaatgt attacgaaaa taatattatg agcacattag ctcttgttga
     2101 agtgatgtca gagtttaatg ttaaaaagat tgtattttca tcgagtgcga ctgtatacgg
     2161 cgttcacaat cattctcccc ttattgagac gatgccgaca agtgcaacga atccgtatgg
     2221 gtacacaaaa gtgatgcttg aacaaatttt aaaagatgtt catgtagcag attcagagtg
     2281 gagtattgcg ttgcttcgtt atttcaatcc gattggtgct catgagtcgg ggttgattgg
     2341 agaagatcca tcaggcattc ctaacaactt aatgcctttt attgcacaag tagcggtagg
     2401 taagcgacca gagctaagtg tttttggaga tgattatgat acggtagatg gtactggtgt
     2461 tcgcgattat atccatgtag tggatttagc gatagggcat ataaaagctt tagaaaaagt
     2521 atctgaaaaa acagatgttt atatttataa ccttggttca ggagaaggca caagtgtatt
     2581 acaacttgta aatacatttg aaagtgttaa taaggttcca attccgtata aaattgtacc
     2641 aagacgatca ggagacgttg cgacttgtta tgcaaatgca gacaaagcat ataaggaatt
     2701 aaattggagg acaacaaaat cgattgaaga catgtgtaga gatacatgga attggcaatc
     2761 aaaaaatccc aatggctata attgatgata ctgtctatat gagtgctgta ttttggaaaa
     2821 attacttaac cttttaatga aatgcatatt taatgaaaga taaatttttt taaaaaaatg
     2881 tttgaaagcg cttgacaaag tgaacggttt cattgtataa tgtaaacata atgacaccga
     2941 tgtcaaatat aaaaaagagg gtctttatat gaaaaaccta acaaaaatta agttcaaaga
     3001 aaatggagaa tttaatcatt ttccaggaaa tactgttgta gcaaatcttt atactaaaca
     3061 agatttgatg gaagttgttg atattattca atcacgttat agagaattac catttatcga
     3121 taagtttact ttaactccaa ggaattctat tcacatgact gtaattgaat tgttgtgcca
     3181 tgaaaatcgt gaaacggagt tttggagcag taatcttcct cttgatacac ctttacagga
     3241 aatacatgat tactttgcta aacaacttga aatttttcca ttgttggatg aagaaattca
     3301 tatgcgtgtg actgaaatgg gaaaacaaaa catactagtt gaacctgcag atgaagcttc
     3361 tgcaaagaga ttagaagaaa ttcgtactta tgtctcagaa aaagcaggtg ttcgtttccc
     3421 taatcatgat agatatcaat tccatatttc aattgggtat cttcggattc ctctaaccga
     3481 agaggaggaa gaagagttta ctaaagtcag agcagaatta actgaaattt tattagagaa
     3541 gattccaact attactgtaa accgtattga ctatactgta tttgaagata tgagacaatt
     3601 tgttccatat catgaaaaat ttaaataaaa taataaaaaa ggagaactta tcatgaaaaa
     3661 aatgaaagtt tggtctactg tacttgcaac gggagttgct cttactacac ttgctgcttg
     3721 ctctggaggt tcaaattcta cgactgcttc ttcatctgaa gaaaaagctg ataaaagtca
     3781 agaattagta atctattcga actcagtctc aaatggtcgt ggtgattggt taactgctaa
     3841 agcaaaagaa gctggtttta atataaaaat ggttgatatc cctggcgctc aattagcaga
     3901 ccgtgttatt gccgaaaaga ataatgcagt tgcagatatg gtatttggaa ttggtgctgt
     3961 tgattcaaat aaaattagag atcaaaaatt actagtacag tacaagccta aatggctaga
     4021 taaaattgat caatctttat cagataaaga taattattat aatcctgtga ttgttcaacc
     4081 attagtttta attggggcgc ctgatgtaaa agaaatgcct aaagattgga ctgaattagg
     4141 tagtaagtat aaaggtaaat attcaatttc tgggctctca ggtggaacag gacgggcaat
     4201 tctagcaagt atcttagttc gataccttga tgataaaggt gaattaggtg tttccgaaaa
     4261 aggttgggaa gtagcaaaag aatatttgaa aaatgcatac actcttcaaa agggagaaag
     4321 ttcaattgtt aagatgttag acaaagaaga tccaatacaa tatggaatga tgtggggttc
     4381 tggtgcttta gttggacaaa aagaacaaaa tgttgttttt aaagtgatgt ctcctgaaat
     4441 tggggttcca tttgtaactg agcaaacaat gattttgagt acaagcaaga agcaagcatt
     4501 ggctaaagaa tttattgatt ggtttggtca atctgaaatt caagtagagt acagtaaaaa
     4561 ctttggctct atccctgcca ataaagatgc cctcaaagag ctaccagaag atactaagaa
     4621 atttgttgat caagtgaaac cacaaaatat tgactgggaa gctgttggaa agcatttgga
     4681 tgaatgggta gaaaaagctg aattagaata cgtaaaataa gaaataagag ttatttttta
     4741 tgtccaagtc tctctattat ttctaaattt aaggaagaaa taaagagagg cttttggttt
     4801 agtaatagag ggagttagtg agatgattaa atttgataat attcaaatta aatatggtga
     4861 ttttgttgca attgataatc tgaatttaga tatacatgaa ggggaattct ttacatttct
     4921 tgggccttca ggatgtggta aatcaactac tttgagagca ttggtaggtt ttttagatcc
     4981 atcatcagga agtattgaag ttaatggaac agatgtcact catttggaac ctgaaaagcg
     5041 tggaattggt attgtatttc aatcttatgc gctatttcca actatgactg tttttgataa
     5101 tattgcattt ggtttaaaag ttaagaaggt agctccagat gttattaaag ctaaagtatc
     5161 agcagtggca gcaaaaatta agatctctga tcaacagtta cagcgtaatg tatcagaatt
     5221 atctgggggt caacaacaaa gggtagcatt ggctcgtgct ctggttcttg aacctaaaat
     5281 tctttgtcta gatgaaccat tgtcaaacct tgacgcaaaa ttacgtgtag atttgagaaa
     5341 agagttgaaa agacttcaaa aagagttagg tattactact ttatatgtta ctcatgatca
     5401 agaggaagcc ttgactttat ctgatagaat tgcagtcttt aacaatggat acatcgaaca
     5461 ggtcggtaca ccagtagaga tttatcataa ttctcaaact gaatttgtat gtgattttat
     5521 tggagatatt aatgttttga ccgatgaaac agtccacgaa gtattactga aaaatacaag
     5581 cgttttctta gaagataaaa aaggttacat tcgattagag aaagttcgat tcaatcgtga
     5641 aactgaacaa gattttattc taaaagggac aattattgat gttgagtttt ctggagttac
     5701 aattcactat acaataaaag tttctgaaag tcagattctt aatgtaacaa gtattgatag
     5761 tcaggctgct attagatctg tcggagaaag tgtggaatta tttatcacac catcagacgt
     5821 tctgcaattt taaggaggtg cagtatgcgt cataaattaa atttaaaaga ttggcttatt
     5881 cgtttaggat taatctggtt cttagtaaca tttattattt atccaaactt tgatctagta
     5941 gtgaatgtat ttgtaaaagg aggagaattt tcccttgatg ctgtacatcg tgttctaaaa
     6001 tctcagaggg cacttcagag tattatgaac agttttaagt tagcattttc actcattatt
     6061 acagttaatg tcgtaggtat tctttgtgtt ctatttacag agtactttga tattaaaggt
     6121 gctaaaattt taaaattagg ttatatgacc tctttaattt atggaggagt ggttttagcg
     6181 actggatata aatttgtcta tggtccttat ggattgatta caaaattttt acaaaatgtt
     6241 atcccttctt tagactctaa ctggtttatt gggtatggtg cagtcttatt cattatgaca
     6301 ttttcaggaa ctgctaatca tacattgttt ttaacaaata caattcgaag cgttgactat
     6361 cacactattg aggctgctcg aaatatggga gcaaaaccat ttactgtttt ccgaaaagta
     6421 gtgttaccaa ccttaattcc aactctattt gcacttacta ttatggtttt tcttagtggt
     6481 ttatctgcag tagcagcacc catgattgtt ggtggtaaag aatttcaaac tataaatcca
     6541 atgattatta catttgcagg gatggggaat tctcgtgatt tagctgcctt acttgcaatt
     6601 attttaggta ttgcaactac aattttgctt actatcatga ataagataga aaaaggtgga
     6661 aattatattt ctatctctaa gactaaagcg cctcttaaaa aacaaaaaat tgcgtctaag
     6721 ccttggaata tcattgctca cattgtagca tatggattgt tcacagtttt catgcttcca
     6781 ctaattttta tagtattata ctcatttaca gatccagttg caattcaaac aggtaactta
     6841 acattatcaa actttacttt agaaaattat cgcttattct ttagtaatag tgcggcattc
     6901 tctccattct tggtcagctt tatttattct attattgctg cgacaacagc aacaattctc
     6961 gcagttgtat ttgctcgtgt tgtcagaaaa cataaatctc gttttgattt cttatttgaa
     7021 tatggtgctc tacttccttg gttactacca agtacacttt tagcagtaag tttattattt
     7081 acttttaatc agccacaatt tcttgtcttg aatcagattt tggtaggtag tttggtaatt
     7141 ctacttattg catatatagt tgtaaaaatc ccattttctt atagaatggt acgtgctatt
     7201 ttatttagtg ttgatgatga gatggaagat gcagcaagaa gtatgggtgc ttcacctttt
     7261 tatactatga tgaaggttat cattccattt attttaccgg ttgttctctc tgttattgct
     7321 ttaaacttta actctttatt aactgacttc gacttatctg tattccttta ccatccccta
     7381 gctcaaccat taggtattac gattcgatct gcaggtgatg aaacagcaac atctaatgca
     7441 caagctctgg tatttgttta tacaattgtt ctgatgatta tttctggaac ggtattatac
     7501 ttcacacaaa gaccggggcg taaagtaagg aaataatcat gacagccact agtcttgggt
     7561 tatcaaatat tgaaatagtt gtcaggattg ttttatcagt agtcattggt agtataattg
     7621 gtttagagag agggagcaaa tcccagcctg caggcatccg aacttatagt attgtttgtc
     7681 tagctgcatg tttgattatg atgacgaatg aatacgtatc ttataaattt gggacaggag
     7741 atcctacacg attaggagct caagttatat caggtgtggg ttttctaggc gctggaacga
     7801 ttcttattac agataaaaag aaaattacag gtctgacaac tgcagcaggc atttgggctt
     7861 cggcaggaat tggattagct attggagtag gtttttatga gggagctctt ttagtagcca
     7921 tttctgtttg gggtgtgata tccatgttcc aaccactaaa aaaatatctg caaaatcgtt
     7981 ctaaaatgat tgaattgtat atagtggtta aatctacaga agcctataat cgtgtattgg
     8041 tttattgtgc agaaaatggt atcagaatga ccgattcaag aacagcgttt ggagatgtta
     8101 attctgacag aattgaatac tttgatgttc cggacaaaaa aatagcgtca tttattactc
     8161 tggaattatc aggtagattt gaacatcttc gactgatgga agaaattgct aatattgtag
     8221 gtgttattta tgtcgaagaa attagctgaa atttagtaaa caaagggaca gatgtttttg
     8281 tccttttgct ttttagatgt tttaatcatc taatttttga gtagattttt gctcagaggt
     8341 ttttatgaaa gattataaaa tcaattttga tttaggtaaa atagaatatt ttgataataa
     8401 ttgtttgata caagtataca aatttatttc tttttatgat atttgtgaaa tggtgtttgc
     8461 ctttcattta cctcctgatg agttgataac aaatgttatc tttaaagaaa aaattaactc
     8521 tatgttaaaa tgttacattg acaggctatt atatgttttt ataaatccta cacattttac
     8581 tgaaaaagtt aatctacaat tttatggcag ttttttctca tatgaattta tttgtcgtga
     8641 agttggaaac attcttaaaa ataaaggtgt gaaatg
//
LOCUS       DAVMJI010000052         7984 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.053, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000052 DAVMJI010000000
VERSION     DAVMJI010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7984
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.053"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(168..476)
                     /locus_tag="VYR58_001891"
     CDS             complement(168..476)
                     /locus_tag="VYR58_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV3622991.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(473..781)
                     /locus_tag="VYR58_001892"
     CDS             complement(473..781)
                     /locus_tag="VYR58_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV3622992.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(786..2081)
                     /locus_tag="VYR58_001893"
     CDS             complement(786..2081)
                     /locus_tag="VYR58_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV3622993.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVNRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2099..3508)
                     /locus_tag="VYR58_001894"
     CDS             complement(2099..3508)
                     /locus_tag="VYR58_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV3622994.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKSIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            3666..4394
                     /locus_tag="VYR58_001895"
     CDS             3666..4394
                     /locus_tag="VYR58_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV3622995.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            4854..5048
                     /locus_tag="VYR58_001896"
     CDS             4854..5048
                     /locus_tag="VYR58_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV3622996.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5414..6724)
                     /locus_tag="VYR58_001897"
     CDS             complement(5414..6724)
                     /locus_tag="VYR58_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV3622997.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            6961..7833
                     /locus_tag="VYR58_001898"
     CDS             6961..7833
                     /locus_tag="VYR58_001898"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV3622998.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2463 a         1403 c         1530 g         2588 t
ORIGIN      
        1 ctacagtgga ctattctaga ttcaacatat tataaaaact agagtaaaag aaaaggattg
       61 gatcttgtgt aatgcaggat ccaatccttt caatcatttt gtccaacttt tggaggttcc
      121 tacaatgtag tcgtcattaa taaagacaga tgggaatgac agtgttccta tttattttga
      181 tagagatcga tgaattcttt agatagcaac tgaataatct ctgttgaagc catttggtct
      241 tctgcatgca taaatagcaa ggagaatcct attttttctc cagtagcttc tttttgtatg
      301 agattagagt gaatcttgtg cgcttctact aaggagtctt ccgcttcttc aactttaatt
      361 ttcgcttctt ttaaatttcc tgccttagct agttggatgg cttcaataaa ggatgatttg
      421 gctgctccac tattggcaat gagctgaaaa cagatatatt ccatttcttc tgtcatctta
      481 tttctcctat ccatgcaagt gcttgttcca gaacttttgc tccattcatc attccgtaat
      541 cccgcatatc aatggtatct acagggatat ttcctgcaat ttctttcaca gcaagtaact
      601 cataacgaat ttgtggccca attagaatga catctgcttc atggatattc tttttagctt
      661 ctgtcattga ttttgcttgg atagagattt caatcccacg ttcagtcgca ctttgttgca
      721 tttttttaac aagcatactt gtcgacattc ccgcattaca tactaataaa atttgtttca
      781 taatcttaac cttccatttc ttgttcaaca actttgtcat taactttgat aaatggaatg
      841 tatagaagaa ctccaagtgc aaagatgatg aattgaacta gaactgctct cacgtcccct
      901 gctgttgcta accatgcatt taagaatact ggtgtagtcc aaggaacttg tataaatgca
      961 ggactcatga atcctgtaac tgttgctaag tagctgatta aaataccaag gactggaact
     1021 gtgataaatg gaatagctaa tgaaatgtta taaacgattg ggtaaccgaa taatactggt
     1081 tcattgatat tgaagatacc aggtccaaaa gataatttag ccacgttttt agagacagca
     1141 ttgcgactca ctaagaatgt tgctattaat aaacataatg tagatccact accacccatt
     1201 aaagcgaatg tttgtatttg tgataggttg atgatgtgtg gaatggcttg tccattattt
     1261 gctgcagtga tgttttcagt aatgttaatt aatagtaatg gttctaggat ggcactgtaa
     1321 ataactgctt ggtgaatacc aaatagccat aacatatttc ctaaagagta aataataatg
     1381 accccgatta agcttgtacc aatatgacga attggttctt gaataaagat tgtaatgatt
     1441 gagattaagt tcattccagt tatattgaat aataatgctg aaacaacccc aaataaggag
     1501 atgacggtca tgactggaag taatacgcta aatgatctat taacagctgg tggaatattt
     1561 tcaccaaggt tcatttgtaa agctttaaca tttgataatt caatgaataa ttctgttgca
     1621 ataatcgcta cgataacccc ggcgaacatt gcgcctgtac ctgtgttgtt gaatgaaaga
     1681 acacctgaaa tgtttacagc atcttttgct ccgtcaggaa ctacagaaac tgtatttggc
     1741 atcatcacaa ttaaagaaac taatgatagc attgatgctg ctaacgggtt ttcgaaatct
     1801 ctgtttttag ctaagaaata accaaccatt acagcaataa tcatacctga aatacttaaa
     1861 gtaccgtttg caattgttat tccccaatat tggaatcttg ttaatgtatc cccttggaaa
     1921 atccacttaa ataccgtgtt gttcaaaaga acgattaaac ctgccaaaat atataatggc
     1981 attactgtta cgaatgcatc tcttagggtt tttaaatgaa tttggttccc tagtttacca
     2041 gcaaaggtgg caaattggtc tataaatttt gagtttttca tatgaatatc tcctctcttt
     2101 actcctcaat ttctacttca aaaccgttat tgtcacttac tttgcgatac catcttcctg
     2161 agctcttgat ggttctcttt tgcgtttcta aatcaacgga gataaatccg taacgattct
     2221 tatatgcatt attccaagac cagcaatcaa atgcggtcca agcgtggtat ccaaaacagt
     2281 gacttccctc ttcaatggct ttatgtagcc atcttaaatg ttcttcataa aattcaatac
     2341 gatacacgtc atcgataact ccattttcat cgataaaccg tgcttcgttt tcaacaccca
     2401 ttccgttttc actgataaac catgggatat taccatattc ttccttcaca atcatagcaa
     2461 tatcataaat ggatttcgga aaaatttccc aaccacgata tggattcatg cgacgctccg
     2521 gccattcata ctctttgaag tattggtctg gcatccaggg cgtctgatat tcctcaggat
     2581 ttgcttgtgc ttgaacacgt tttggatggt agtagtttac tccaagaaaa tcaaccgtat
     2641 ttgatttcat cagttgaagc tctttttcgg tatgactcca taacacgcca tctctctcta
     2701 gctgttttac caatctttct gggaaagttc ctttaacagc tggattcaag aagactttgt
     2761 taaagaagtc atctgtaaat cgacttgctt ctaagtcttc tggagaatta cttcttggat
     2821 aagcaggtgt caagtttaaa ataatcccaa tctttccatc aagttctaat gagcgatata
     2881 gttgaatcac ttttgcacta gcaaggttta gattatagat gacttgtacg gcctcttttc
     2941 cctttccttt tagatttgga taatggaaag catataagta tcctgcttct ggaatgacca
     3001 ttggctcatt gaaagttgtc cagtaatgaa ccttatctcc aaagcatgtg aaagcagtct
     3061 tggcaaactt cacgaataac tccactacat gtttgctttc ccaaccaccg tatttttgaa
     3121 gaagttccac tggtaaatca aaatgatgta aattcatcac aagatccatc tggttctttt
     3181 tagcttcttc aatgatggca ttgtagaaag caataccttt tggatcaggc tcacctgtct
     3241 ctaaattctt gatgagtcga ctccattgga tggaagtgcg gaaagaatta actccaattt
     3301 ccttcatcaa gtggaaatct tcggtgtaag tatgaaaaaa gttactggct acaagaggtc
     3361 cgacattatc gaaaaaatct tctggatgcg ttttgaacca gtagtccatc acattttcat
     3421 gtacttttcc atattgacct tctgtctgag gtccgctaga agctgctccc caccaaaaca
     3481 gattaggaaa tactaacttt tttttcatgc tcaacctcct ttctattatt ctatacataa
     3541 agtatagcat aattttaaaa tttgtctaga catttttaaa aattgttgat acatatcttg
     3601 tgtttgcctc atttcttgaa ctttgttata ctactattag aatattatag agagaaccag
     3661 attaaatgag tacaaaatat ttatttattt acaatgagat tcgtgaaaag attctttgta
     3721 ataaatatac catgaacgaa caattacctg atgaaatgac attagctaaa cagtttgcct
     3781 gtagtcgaat gacgatcaaa aaagctttag acttgttagt ttctgagggc ttaattttta
     3841 gaaaacgtgg gcagggaacc tttgttctct ctcgtggcag ctcaaaaaga aaattaatcg
     3901 ttccagaaag agatatccgg ggactgacaa aaatatctga agatgctcat tctacaattg
     3961 actcgaggat tattcacttc aaattagaat ttgcaaatga atttttagca gaaaaactac
     4021 aggtcgcttt gcagagtcca gtttataata tttaccgcct gcgtattatt gacggtaaac
     4081 cttatgttct ggaacaaact tatatgagta ccgatgttat tccaggtatt actgaagata
     4141 ttttacaaaa atcgatttac aattacattg aaggaaagtt aggattgcat attgccagtg
     4201 ctacaaaaat cttacgagct tcttctagtt cagaaaatga gcaacattac ttgcagctcc
     4261 ttccaacgga accggtattt gaagtagaac aagtggctta tttggataac ggaactccgt
     4321 ttgagtactc gattagtcgt catcgctatg atttatttga atttaattct tttgcattac
     4381 gacattcctc ctaggagaaa atgtgaaaat gaagccaatc ttttacagac tctagtttaa
     4441 gaaaaattta aaacagggca agaaggtccc atctatgctt aaatggtttc tcttttctaa
     4501 ataagatggc tttaaaagag tgatcgtttt atccatcatg ttgaaaaata tcttcgtata
     4561 gcttatagag taggtactga aattgttcac ctgatctact tcttatagtt atttagtttt
     4621 aaatagtgtt tcaaatattc ttacactgac gagaagtttt tgagtctttt cttgtaacac
     4681 atatagtata ctgaggttag aatagtagac tgtgacttct aacaaattgc tagaaatgaa
     4741 tttcaatctc ccaatttatt tgttcaaata ttgttttaat atattgaata aattctgaat
     4801 cataatcatt taaaaaaatt ttattttttt atttttcatt acgaataata tagatgaagg
     4861 ggaaagagta tgaaaacaga actgtttctt ttgctattag ttcaaaagga gaaaaaatga
     4921 aagtagaaaa tatttcgtat agggtggatc atcgtatatt gtttgataat atttcttttg
     4981 atacttcgag ttcaggcgtg acattaatta ctggtaaaaa tggtacagga aagtcaactt
     5041 tactatagta gattgaaact agaatagtac acatctactt ctaaaatatt gttagaaatc
     5101 gatttgacta tcctgatcta tttgtcctgt tcttatttca tttcactata tctcaaattg
     5161 agtatgacga agtgcgctcc catgtcctgg gaacgcactt tcttcatatt tttcatattc
     5221 ttgaatccat cgataaagac tattgggatg aatttttaaa gttgaactaa tcatttttac
     5281 aggatgagat ttacagcaga gagtttgaag gctttatcaa aggtttttct tggcataatg
     5341 acttttcctc gtttccactt aattttgtgt ctactttatt ataccaagtc cacccttaag
     5401 ttagataata aatctaactt aaggaagcta gaaggatgag aatccaggtg gtcaagagtc
     5461 ccaaacttaa gctgatgggg acacccagaa taatttgctt tttgaaggca aggccacgtt
     5521 cctctatatt gggaagtgag agttgaatga gagaaccagc tgatgaaaag ggtgagatat
     5581 tagtagatag agcgccaata acggtggctg ttgtgagtaa gtgaatatca atctgaggat
     5641 tttgagcact gatgatagca atgatgggaa agagggctgg agctacaacg gatagggtgg
     5701 aactaaagag tgacatcact ccggctatca cacaaaagaa cagaggtaac cagaaatgag
     5761 gaatggttgt tgtcatgagg tgccctatca gtgtgactaa acctgacttg accgctagag
     5821 acattagtaa gctcatgccg cagagcatga taattgtagc ccagggaacc ttagctaaaa
     5881 tggcttcttg cttccctaat ttgagcctta aggcgaggca gaccatgagt attgagacaa
     5941 agccaatatc aaatgttttt tgataagtag ctatccaggc gatgtttggg aaaatgagat
     6001 gcaacaaggg aaaaagccaa accaaaacca tgctgctgat catgagcaag gtggtttgtc
     6061 tttgaacctt gctgaggagt ggtggttggt caatagtcaa ggatgagttt gttcttccct
     6121 tactatagtg actgtaacag gataataaaa gcaagacgat gagtgggtag ataatgctga
     6181 cgataaagat atgattgcca agtgaaaaag cttgctcttc ccatcccatt tgcttaaaca
     6241 ggccttgaaa gacaatgcct gagctactgg ttatcaaatt agcccctcct gaagctcccc
     6301 aattgacggc ttgagctcca atcaaagggt gtttgtccgc tttttgacag agggtaatcg
     6361 ctagaggaca gcaaacggcc atagtagtga aaaatccagc acctaaagca gacaaaaggg
     6421 ttgccatcag gtataaaatc atgtagaggg cgttagggtg ggtgcgtgtg cggtagagaa
     6481 tgtgttgagc caaaacatca agagtaccgt tagttgttgc aacgttataa aagagagaga
     6541 cgctaaaaat ggtaaaaaag agtgaggttg gccaaaaatg aagaagttct ttggggctta
     6601 atcccatgag agtggttgcg atgaggtaag aaaaagcaat agccagcagg ccaatattga
     6661 ttttggtgcg gtaaccaatt ccaatggcta gagcaatggc gctaatcatt attaaatgaa
     6721 tcattgaatt gtcctttcag ttagaatatg gaaataggtt ggcaattttg gcgctcaaaa
     6781 gaccacctgt ttcctattgg tacttgacta ttatacacaa aaaaaataca attgtcttga
     6841 caattgtatt gacacttgtt agaattaaaa atgaggtatt caggcttgtg atttcctatg
     6901 gaagttaata gtaattgcct ctagtgctta caagtgatat taaaaataga ggacttagtg
     6961 atgtcaatca tttcaactga tttaacccct tttcaaatag atgatacatt gaaagcagcc
     7021 ttgcgagaag atgttcattc cgaagattac agtaccaatg ccatttttga tcatcatggc
     7081 caagccaagg tgtcgctttt tgccaaggaa gctggtgttt tagcgggact aaccgttttt
     7141 caaagggttt ttaccctatt tgatgccgag gtgaccttcc agaatcctca tcaatttaag
     7201 gatggggatc gtttgactag tggcgatttg gttttagaaa tcataggctc ggtgagaagt
     7261 ctcttaacat gtgaacgcgt tgccttgaat tttttacaac atttatcagg gattgcttcg
     7321 atgacagctg cttatgtaga agccttaggc gatgattgca ttaaggtatt tgatactcga
     7381 aaaactactc ctaatttacg tctttttgag aaatatgccg tgagagttgg cggtggctat
     7441 aatcatcgct ttaatttatc agatgctatc atgctaaaag acaatcacat tgcggcagta
     7501 ggtagtgttc agaaggcaat tgctcaagcg cgtgcctatg ccccttttgt gaaaatggtc
     7561 gaggtggaag tggaaagcct tgctgctgcc gaagaagctg cggcggcggg tgctgatatt
     7621 atcatgttgg ataatatgtc attggaacag attgaacagg ccattaccct aattgcagga
     7681 cgttctcgga ttgaatgttc tggaaatatt gatatgacca ctattagccg ttttcgtggt
     7741 ttagcgattg attacgtctc cagtggtagt ttaacccata gtgctaagag tcttgatttt
     7801 tccatgaagg gtttaaccta ccttgatgtc taagttgtaa aataaactaa ctttttaaag
     7861 gatgtctttc ctctagaacg agttttatgt cagatagttt aaacgcctct tcaaatatag
     7921 taaaatgaac caaaaatagt acacaatgtg gtataatctt cttatggcat attcaataga
     7981 tttt
//
LOCUS       DAVMJI010000053         7774 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.054, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000053 DAVMJI010000000
VERSION     DAVMJI010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7774
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.054"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(141..437)
                     /locus_tag="VYR58_001899"
     CDS             complement(141..437)
                     /locus_tag="VYR58_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV3622999.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(980..1873)
                     /locus_tag="VYR58_001900"
     CDS             complement(980..1873)
                     /locus_tag="VYR58_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3623000.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(2627..2857)
                     /gene="blpU"
                     /locus_tag="VYR58_001901"
     CDS             complement(2627..2857)
                     /gene="blpU"
                     /locus_tag="VYR58_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV3623001.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAVGGAILGGVAYAATCWW"
     gene            complement(3060..3350)
                     /locus_tag="VYR58_001902"
                     /pseudo
     CDS             complement(3060..3350)
                     /locus_tag="VYR58_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(3396..3629)
                     /locus_tag="VYR58_001903"
     CDS             complement(3396..3629)
                     /locus_tag="VYR58_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV3623002.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(3635..4627)
                     /gene="plsX"
                     /locus_tag="VYR58_001904"
     CDS             complement(3635..4627)
                     /gene="plsX"
                     /locus_tag="VYR58_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV3623003.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(4624..5394)
                     /gene="recO"
                     /locus_tag="VYR58_001905"
     CDS             complement(4624..5394)
                     /gene="recO"
                     /locus_tag="VYR58_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV3623004.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(5391..6560)
                     /locus_tag="VYR58_001906"
     CDS             complement(5391..6560)
                     /locus_tag="VYR58_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV3623005.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            6709..7719
                     /locus_tag="VYR58_001907"
     CDS             6709..7719
                     /locus_tag="VYR58_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV3623006.1"
                     /translation="MSFLSKNGAGILVCLLISILSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
BASE COUNT         2265 a         1821 c         1229 g         2459 t
ORIGIN      
        1 aatttccctt gaaaaggaag atagctttta aaatagattg acaaacttat gataacaaaa
       61 aacaaaaggg ttatcccaat aaaattaaga taacctaaaa tactttcaca ttctttttta
      121 gaaagtattt tcatctagtt ctaccataga gctgctttag cagcaccttt ctttttcaat
      181 atataaagaa ctgttgctgc aatacccgaa ccaatagaac ctactcctgt gattgcacct
      241 acaattgaaa ttactgctgt aactgtacta taagcactaa tcaaattgac tacagtagca
      301 gcagcttttg tcgaaattcc taatgtccca gccaacatag gaaaagaaac aacacctaag
      361 cttaaccaac taatgactgc taacattgct gaaacaataa gaaatttatt atgaaattcc
      421 attcttttag atttcatttt agtgtactcc ttttgtatat tatgtatgtt ttattgagag
      481 ttaattcgca catgttgtat tcctaactct cttcaaatgt tcgtctatat tttatactac
      541 ttttattaac atatctataa taaataaatt actactacat tttcctagat tatcaaatta
      601 cttttatatc actaagactc aataaaagat aatgtctatt taacttttat acgattacta
      661 cctccttttt agtttacact tcctacatca taaataaaca tactcaaccc tcacaatctc
      721 caaataactc ttctatatca ttgaaaattg agtttcatcc tctatactaa tgtaggaaac
      781 ctattaaaac attcctttaa tccaatataa gaataccttg ttccattaat ctctacccga
      841 tattatagat agaaccaaat tcctatactt aaaaggacaa ataacgttcc acccataata
      901 aacctccttt ctttttgaga gcgttttctt tataggttta gtatagcaaa aacatgaaaa
      961 aaacaacatg acttagaagt caggttgttg ggaaatctat ctgtttttct gctaaaattc
     1021 tctgaactaa tacctgatcg tctagcaatt ctgctagaga aatcgccttt tcatagaaac
     1081 tttctgcctc taaaatattc ttgtctacaa ataaagcata ttttgccttt agcaaaaata
     1141 gatgaggtcg gtaaaaaaca tgtcttgttt tagcaataat tttctcaaat gtttgaatat
     1201 atatcagact atcttctgtc tgaatttgga taaataggct cagaagaact ttttccattt
     1261 gaactaggct agccttatct tcatattctg aacatagcaa tactttttga gctaactcct
     1321 caaaatgttc tttatcttct aatcccatag cacaacaaaa gaaatacaat tcaataatca
     1381 acaaatcatt tacagaaaaa tatttctttt ttaataactg ctggaaatat tcttccacta
     1441 accctaaacc gtaggtcaca tctgaactac cataaatatc aaaacgagct tgtgtcacat
     1501 ccacaattaa ctgctcttcc tcaggcaaat tctcataata gttttcatat atttcctcaa
     1561 gtatagcttc ttttcgttcg attcttccct tatcagcgta ggtttgagaa tgaatcagct
     1621 catctttgag ttttaggaat ccttttggaa tctctataac cttaacatcc acaatattct
     1681 gtaatgatac tccaagttta tccgcaatca ataataattt aggaagtgtt gctaaagctt
     1741 gcccattttc aatacgtgct agctgacgaa tcgtcaactc tgattcatca ccacaaatat
     1801 ctatctgagt ttttccacaa gatcgcctaa tagttttgat tttataacca atttcacgtt
     1861 tcaactcatc catagtaata ctccttaagt tgattacaaa gatttctttt tcttcctaat
     1921 tcttttgtca atcatatata aaacgataag cgaaaacagc ggtagaacaa tataactctt
     1981 ttcactcatt atcagctgaa atcccagggt tgctagtatc ttaaagatga aaatattcat
     2041 caaaaataga aaaacaaata ctaaaaaata ttttaaaacc ttcttcattt cttttcttca
     2101 actttcctaa tttctacacc tattttatcg aaaatatata taaaactcca aataaacact
     2161 tcgactgcac tttttttggc aaaaaataga cagaacaaac atcctaccta ctaaaaatat
     2221 gatatgaaag gaaaatgatt ttttactgac accctaggca agcttgggac aaataaatca
     2281 ttgatagcaa catttacgac atcctattta aagttccttc aatttctaat gtccccgcta
     2341 tttctaagcc acctctggta tgatctattc ctagtcagaa tagataacac cgttctaaat
     2401 tacgattcat agttactcct tttttgactc gttactataa gacttctatt tacatgcgca
     2461 aaataatttt gattcagatt catcatttat agttttgatt attttttaac agatttttct
     2521 gttttcttct ccgaagactt taaaaatttt tttctaatta aatcatccat ataaggacca
     2581 aatataccaa ctactaaacc aataataaaa cttttaaaat ccataattac caccaacatg
     2641 tcgctgcata ggccacacct ccaagtatag ctcctcccac agcaccagtt gctgcacctt
     2701 gccatgttct tgttttaatt cctagctgaa gacctcgtgc tgctcctcct ccaacacctg
     2761 ctttggcaaa atctccccaa ttgcatccgc caccttcaac gcaagcaagc atctcagtat
     2821 ccataatttc aaattgtgac atcgtttttg tattcataac gaatacctct tttttatttt
     2881 taatatttgt cttgttacaa acttgacaag tttagtataa cagtatctat taattttttt
     2941 catccaaatc ttgaattggc atcgaaacgt cttgaattag cttttttgtt tcaaaatcat
     3001 ctctattttt aaaaaagatg ttttctaatc acttttttac tattagactt cctgcaaaac
     3061 tagaatccta gttcatgatt gataatacca gcaatcaaat tcattcgtaa tccgaagcgt
     3121 ttacgatgat ttcgataggt tgttgaaaac attttaaacg tttttacttt ggcaaagata
     3181 ttctcaacct tgcttctctc cttagatagc gcatgattac aggctttatc ttcaactgtt
     3241 agcggcttga gtttgctgga tttacgtgga gtttgtgctt gaggatatat cttcatgagc
     3301 ccttgataac cactgtcagc caagattttt ccagcttgtc cgatatttct catttctaaa
     3361 aaccatctac ttccgttgac ttggaactcc gattgctatt ttccttgaat gattttaacc
     3421 acatctccta cgttttggag ttggtcaatt tcttcatcgc tgatttcgat actaaattca
     3481 tcttccagag tcaagataaa ctccatcaag tcaacagaat ccgcatccaa atcgtctttc
     3541 agactcaagg attctgtcac gacaaagtcc tctccctgtc gctcttggat aatggtcaca
     3601 atacggtcaa aaatttcttt ttctgtcatc tcttttattc tcctgaaaat tcacgcgcag
     3661 tctgggcaac tacgtctgtt tctagcatgg tacgaatctg gcgaatcgta ctataaacag
     3721 ccttggcatc gcttgagcca tgagtcttga caacaggtgc cttaacacca aacaagaccg
     3781 ctccaccaac atctgaataa ttgagctgtt ttttcaaacc actgaggctg tccttgagaa
     3841 ggagggcacc tagtttcgct cgaagaccac cacctgtaat agctgtcttg agcaagccca
     3901 tgattcccat agctgtccct tcgatggatt tgagcacagc gtttcccgtg aaaccatctg
     3961 ccacaacaac atctgcaacg ccattcatca aatcacgcgc ttccacgttt ccgataaagt
     4021 tcaaactttc atcagccgcc agtaattcat aagtttcctt acgaagcggg tcgcccttgc
     4081 tactctctgt tccgttgttg agcaaaccaa cgcgtggttg cgcaatgcca cggacatttt
     4141 tagcatagaa ggaacctaga accgcatatt gatggaggtg ctgggctgta ttttctgcat
     4201 tggcaccaag gtctagcatg tcaaaacctt ttccatcaac ggtaggcaag gtagacatga
     4261 gtccaggacg gtcgatattc ttgatacgac ccacgatgaa gaatccagca gccaacaagg
     4321 cacctgtatt cccagccgaa aggacagcgt ctgcttcacc atctttgaca gccttggctg
     4381 ccaataccat actggcattt ttcttattcc taatagctct cgtaggttca tcatccgaat
     4441 caatcttctc atccgtatgg ataatgctga cgcgctctgt cgctgtcaga tattgcttga
     4501 ttttagcttc atctccgtaa agttgaacct cgatatctga aaagtcagat agggcttgat
     4561 tgacaccctc aacaatggcc tgaggtgcgt aatcgccccc catggcatct actgcgattt
     4621 ttttcatttc ttttcctctt ttagtaattg tccccagtct gctagggaat caataaattt
     4681 ctttgatttt aggtgaatcc caacgtactc ttcatataat tgatccataa attggcgtag
     4741 ctcttgcttg attccaggct tgagcgaaat ggtctccaaa gtctcaaaat caatagcttg
     4801 aaattgattg agcagatagg ggatattggg attgagatga caacgtctct tatcctcatg
     4861 ataatgctct ggacagaggc aggctccata tttgaaagaa aagtcaaaag cctgaccaac
     4921 ccgatggcag aagacacact cattaaaatt gaggctgatt ccaaatcgag tcaaaatttg
     4981 aatttcaaaa atattggtca aaacctgata atccaagcct gcttccatca actccaaagt
     5041 cttttgcaaa aaagcaaaca agggagcatc ctgctgattg tcctgcaaac tagcatctgc
     5101 aagagctgcc acataggtcg cataggccat gacaaagagg tcactattaa tcttgggaaa
     5161 agtcatgacc tcatgatagt cttcgatgta actgagtccg tcatcattga ttcgcaatag
     5221 aaatcgtgcc agcaccaagg gctgaataac aggcgccagc ttagactgac cagcgtgttt
     5281 gacaaaaaac atgcgtttgc caacctgctc tgtaaaaatt ttgacgagct tgtcatcctc
     5341 acgaaaattg cgattgtaaa gcaccaagcc ttgactcgtg atagactgaa tcatgcttct
     5401 ctcatgtact cctcaagtcg tttcatggct tctttgatag tctccatgct ggctgcataa
     5461 gataggcgga cgtagccttc cccgtaacgt ccaaaggctg caccagggat aaaggcaacg
     5521 gccttcttct gagcaaaatc cttcagaaaa gcaaaggagt cttgattgta gcccgctgga
     5581 attttagcaa aaatatagaa ggcaccgtct ggtttgataa tctcaaaacc aagagcagtc
     5641 attttttcga tgatatagtc ccgacgctgg atatattcct tcttcatggg ctccgcatca
     5701 tttttaccag ccgtcaaggc ttctaccgca gcatgttgcg ccatggtatt tgcggcagtg
     5761 accaagtatt ggtgactctt gattaactgg gctgtgaagg ccgcaggagc gaaaatcagc
     5821 cccaaacgcc aacctgtcat ggcatgcgat ttagacaaac cattgataat aatagcctgg
     5881 tctctcaaca tcgttcctag agacacatgg gcttcgcctg tgtaggtcaa ttctgagtaa
     5941 acctcatcac agacaacaaa aatttcgtac ttgcgtaaaa cagctgccaa ggcctctaac
     6001 tgctctcgac tgtaggtaat tcctgtcgga ttggctggat agttgagaat aaccgccttg
     6061 agcttatcac cctgctccaa aatggccttc tccaacatct caggagtcaa gacaaaacca
     6121 ttttcagtcg tatcaatctc aacaatttct gccccaacta agttaacaat cggttcatag
     6181 cctggataag caggagctgg caaaagtacc ttgtcgccct cttccaaaat agccgtcaaa
     6241 gtcgcagata aagcctctgt cgccccaatt gtaaccaaga tttcattttc aggagcatag
     6301 tccagttggt acttttcctt aacaaagtca ctggctgcct gacgtagagt cagcagacca
     6361 ctcatccctg tatagtagga ttggttctga tcaatcgctc gcttggccgc ctccttgaca
     6421 tggtctggcg ttgtaaaatc aggttccccc aaggtcaaac gcaagacccc aggaatctcc
     6481 gaaatagcct ggtcaaactg acgaatcaac gaaacttgaa ttttatctaa ctgtttatta
     6541 aagcgcttag ttaagtccat agatacctcc tactttcaaa acgtatctct attatactac
     6601 aaaagccccc cgaccgcaaa aatacattag agaatagctt tccactttct attttacttt
     6661 tcctgtttac aggtctataa tggtaacaga ttctatttgg aggtttttat gtcatttcta
     6721 tcaaaaaatg gagcaggcat cttggtctgc cttctcattt ccatcctatc ttggtactta
     6781 ggaggattct tccctgtgat tggcgcaccc gtttttgcga tttttatggg catgctccta
     6841 catccctttc tctcgtctta taaacaactg gatgctggat tgacctttag ttccaagaaa
     6901 ttgctccagt atgccgttat cttacttggt tttggtctca atatctctca agtcttcgca
     6961 gttgggcaat cttcactccc tgtcatcctt tccaccattt caatagcctt gattgttgcc
     7021 tacctcttcc agcgcttctt tgccctggat acaaaactgg ctaccttgat tggagtaggt
     7081 tcttctatct gtgggggttc tgccattgca gcgacagcgc ctgttatcca tgctaaggaa
     7141 aaggaagtag cccaagccat ctccgttatc tttttcttca atgtcttggc tgcgctcatc
     7201 tttccaaccc tcggcacctg gcttcatcta tccaatgacg gcttcgccct ctttgcagga
     7261 actgcggtca atgatacttc ctctgtaacc gccacagcta gcgcttggga cagtctctac
     7321 cagaccaata ccctcgaatc tgcaaccatt gtcaaactca cgcgcaccct agctatcatc
     7381 cccatcactc tctttctctc ctactggcaa agtcgcgagc aaaaaaataa gcaaggctta
     7441 caactgaaaa aagtcttccc actttttatc ctttacttca tccttgcatc gctcctaacc
     7501 acccttctga cctctctcgg tgtgtctagt agtttcttta cccctctcaa acaactctct
     7561 aaattcctca ttatcatggc catgagtgcc atcggtctca aaactaatct ggtcgctatg
     7621 gtcaaatcca gtggaaaatc cattgttctc ggagccgtct gctggattgc catcatcctc
     7681 accagccttg gtatgcagac ccttatcggc attttctaat actcttcgaa aatctcttca
     7741 aaccacgtca acgtcgcctt gccgtatata tgtt
//
LOCUS       DAVMJI010000054         7146 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.055, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000054 DAVMJI010000000
VERSION     DAVMJI010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7146
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.055"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(78..881)
                     /locus_tag="VYR58_001908"
     CDS             complement(78..881)
                     /locus_tag="VYR58_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV3623007.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(965..1186)
                     /locus_tag="VYR58_001909"
     CDS             complement(965..1186)
                     /locus_tag="VYR58_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623008.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(1665..1874)
                     /locus_tag="VYR58_001910"
     CDS             complement(1665..1874)
                     /locus_tag="VYR58_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623009.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            2044..2316
                     /gene="rpsP"
                     /locus_tag="VYR58_001911"
     CDS             2044..2316
                     /gene="rpsP"
                     /locus_tag="VYR58_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV3623010.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            2336..2575
                     /locus_tag="VYR58_001912"
     CDS             2336..2575
                     /locus_tag="VYR58_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV3623011.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            2843..3047
                     /locus_tag="VYR58_001913"
                     /pseudo
     CDS             2843..3047
                     /locus_tag="VYR58_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            3151..3900
                     /locus_tag="VYR58_001914"
     CDS             3151..3900
                     /locus_tag="VYR58_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV3623012.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSE"
     gene            3970..4488
                     /gene="rimM"
                     /locus_tag="VYR58_001915"
     CDS             3970..4488
                     /gene="rimM"
                     /locus_tag="VYR58_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV3623013.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            4478..5197
                     /gene="trmD"
                     /locus_tag="VYR58_001916"
     CDS             4478..5197
                     /gene="trmD"
                     /locus_tag="VYR58_001916"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV3623014.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELVAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            5209..5547
                     /locus_tag="VYR58_001917"
     CDS             5209..5547
                     /locus_tag="VYR58_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623015.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(5578..5898)
                     /locus_tag="VYR58_001918"
     CDS             complement(5578..5898)
                     /locus_tag="VYR58_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623016.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            5996..6211
                     /locus_tag="VYR58_001919"
     CDS             5996..6211
                     /locus_tag="VYR58_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV3623017.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(6280..6360)
                     /locus_tag="VYR58_001920"
                     /pseudo
     CDS             complement(6280..6360)
                     /locus_tag="VYR58_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(6416..6952)
                     /locus_tag="VYR58_001921"
     CDS             complement(6416..6952)
                     /locus_tag="VYR58_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV3623018.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
BASE COUNT         2307 a         1237 c         1489 g         2113 t
ORIGIN      
        1 atagtggatt tacccactat agatattata gagccagaaa tacagtaccg aatgtggata
       61 ctgtattttt ttggttttta agatttaaaa tcgtagtctt tcaccacttc gatgctgtcg
      121 attgtgatag cagtagttgg cttgtctttt tcatcttttt cggctttagc aatcttatcc
      181 acaacatcca taccgtcaat cacttgacca aagactgggt gtttgccatc tagactaggg
      241 tttccacctt ctttgtaggc ttcgataatt ttctgtggat acttgcttgt agggagttta
      301 gaagaggtat ctgtagagtt ttggttgatg aagaactggc tgccattggt gtttggttga
      361 ccagtattag ccatagcaag agcaccacgg atgttataca aataaggagt aatctcgttc
      421 ttgaaaccag ttcctttgtc tttagtctta tccttgtcat gccatatgga ctgaccacct
      481 gtaccgtccc cttttggatc tccagtttgg accataaagc catcgatgac acggtggaag
      541 gtaataccgt tatagtagcc ttctttggcg tgagtgagga aattttcaac cgctagagga
      601 gcgagtttag ggaagagttt aatgcgaata tcaccttggc ttgtgtggag aatcacttcg
      661 gcttcatctt cagcaacttc cttagatagt tgtgggaaat tggcgttttc gtttgttaaa
      721 gcatcgttta actccttggc agattgggca gctactttgg aactttcttc agcagcaaga
      781 ctggaatcaa cataatcatc accacgcaga ctgcgttgga cgctgctaca cccagctagg
      841 gctacagtag acagtaaaag aagggttgct agttttttca ttctgatcct ctcaaaaatt
      901 catttataac cattgtaccc taaaaggaag tggatttcaa atattagtag tttacagaac
      961 tggcttagat aatagttggg atttcatcat catcttgaaa atcttcaact tcttcaactt
     1021 cttccccagt aaatggtttc tgaaaagaac ttagtataaa acgggcaatt ggttcaacaa
     1081 ttaggaaatt tagaggaaga gctgcaataa agtttacgaa ccaggcgctt agataggtat
     1141 tgggtgtgat agcaatgcca ttgtaaaaaa gtccatagaa ggacatgaaa gtgaccagct
     1201 aattcttctt ctgaaaaatg ctcatgaagg gcttgatcca ggtcgcaaga tttcatttta
     1261 gaaagtccag taactccctt cttcttcagg atattctttt tcatggtagt atttagatgg
     1321 tcaagtgagt caaaagaagt ttcgacaaga gcataccctt tttctaccag agtttttaga
     1381 tgtttagggg catcaatacc ataagtgtac tcaaagtatt ttggaaacca gatcttaaga
     1441 aagctcgtaa agctagccag ttctctaaac gctaagaact agctacaaca cagcatttac
     1501 aacacttcat ggttcacacc atggggtgtt ttttaatgat tttaagcaaa attcacactt
     1561 aattgaaagt tatttaaatt agatgaaaat ttattttttg aaaaagtggg aaaacattga
     1621 ttctaagcga attttgaatc atattcgaat gggagttttt aaaatcatgt ttcagtggta
     1681 aaagtaccaa actggattct ccatagtaaa atgatatctc ctgctagtga atcatctact
     1741 aataagtcca tatttcgctt gggaacgggc ttgggactta gaagccaagt atccaactct
     1801 cgttcaggcg atatgaaggg tttgacttgg tgttctttat aaaatttttc taaaatagta
     1861 ttcacggata gcatctttca aacatttatt tcctattcta acaaatttct aaatacttta
     1921 agaaatttat agtctgtcaa gtttttttct tgacacatgc cagaaatctg ctataataga
     1981 acatgtgcta gatagctcag ctatttcacc gaaataaaaa attaaagaaa tgagacttta
     2041 aaaatggcag ttaaaatccg tttgactcgt atgggttcta agaaaaaacc tttctaccgt
     2101 atcaacgtag cagattcacg ttcaccacgt gacggacgtt tcatcgaaac agttggaact
     2161 tacaacccac ttgttgctga aaaccaagta actttgaaag aagaccgcgt tcttgcatgg
     2221 ttggctaatg gagctcaacc ttcagacaca gtacgtaaca tcctttcaaa agaaggcgta
     2281 ttgaaaaaat tccacgattc taaattttca aaataagttt aaagtaggtt gacagatgga
     2341 tacgattgaa aatctcatta ttgcgattgt gaaaccctta atttcacaac cagatgcctt
     2401 aactatcaag attgaggata caccagaatt tttggaatat catttgaatc ttgatcaaag
     2461 cgatgtgggt cgtgtaatcg gtcgtaaggg tcgcactatt tctgcgataa gaacgattgt
     2521 ctactctgtc ccaactgaat acaaaaaagt aagaatcgtt attgacgaaa aataagaagg
     2581 gcgggacgga tgtctcgctt ttttgtgtgg aatagaagat atagtaaaat gaaataataa
     2641 caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga agtaaaggtg
     2701 tactattcta gtttcaatat actataaaag attgaacgtt taggcaattc caagactact
     2761 tactcgaaca ttaacagcag tctcggactg atgaaggtct ctttatgaag ttagtggaga
     2821 agtcggagaa gtagccgagg ttttgaatag gcgctctggt cgaaaagaag ggataggatt
     2881 cgaacgagga acttgccaga gaactggctg atatcattta ctacaccgtc gcaatcgtag
     2941 ctattaatca tattgacctt accaagactg tctttgagaa agacaaaacc gcagccgtta
     3001 attaccaaca taaacatgat ttggaaggat ttttgaaggg aaagtagaga tgttgtcccc
     3061 ttcctccaac ttgagaaaat ccttggaacg tgataaaata aaagataagg atttttaata
     3121 attcattata tagaatgagt ggatttcttt atgaagaggt ttgaagtatc tacagaaatt
     3181 ggtagcctct ctgttactta tcaaaagcaa aagaaagtgc tagtttgtct aaacggagca
     3241 ggtttgctac caagttatga aaatttttca cttatacttg aaaaacctcc tcctacaatt
     3301 ggttatttga caattgattt tccgaacaca ggtaggagtc cgattcatga ccaagctgga
     3361 aaaaatctag ataatcttgc agatgcggtt tatgaagtac ttgaagaatt aggaatttct
     3421 gaatatatac tttgtgcaca tagttggagt ggaattttag cttgcaaatt actcgagaaa
     3481 ccaattaagc gtcagacttt agtagcaatt gaaccgacaa ctaaaaaagt catgtttgct
     3541 gatttttcag aaaatcctta tccagaaatg gaagagcaga tgaggctgat tgacgagtgt
     3601 ggtcctgaac tttattttaa gaacttaact caagcaacat ttagtcctga aacgaataaa
     3661 aaaatctggg aattaatgca agaaaaaggc ttagagttgg aaaatcaaga tccagaattt
     3721 cagatatctg gagagattac tgaggaagat tttgagaatt tgtcgataga atctcatgtc
     3781 cctgtattta ttttttgtca gacttataga gaaaaagagt acagagaatc agaatattgg
     3841 acttccaata ctaaactcat tttaggaagg aatcaccatt atttacaatg gtcagaatag
     3901 gaaaaaattg cggctattat tcgagaattg tcagaataag atggaaaaaa ggagattaca
     3961 ggagacaaga tgaactactt taatgttggg aaaatcgtta atacgcaggg attacagggt
     4021 gagatgcgag tcttgtctgt gacggatttt gcagaagaac ggtttaaaaa aggagctgag
     4081 ctggctttgt ttgatgaaaa agatcagttt gtccaaacag tgaccatcgc tagccaccgt
     4141 aaacagaaga actttgacat tattaaattc aaagatatgt accatatcaa tactatcgaa
     4201 aagtacaagg gatacagtct caaggtcgct gaggaagatt tgaatgacct agacgatggt
     4261 gaattttact atcacgagat tatcggtttg gaagtctatg agggtgatag cttggttgga
     4321 accatcaagg aaatcctgca accaggtgct aatgatgtct gggtggtcaa acgaaaaggc
     4381 aaacgtgatt tgcttttacc ttatatccca ccagtggttc tcaatgttga tattccaaat
     4441 aaacgggtcg atgtggaaat cttagaaggg ttagacgatg aagattgata ttttaaccct
     4501 ctttccagag atgttttctc cactggagca ctcaatcgtt ggaaaggctc gagaaaaagg
     4561 gctcttggat atccagtatc ataattttcg agaaaatgct gaaaaggccc gtcatgtaga
     4621 tgatgagccc tacggaggcg gtcagggcat gttgctcaga gcacaaccta ttttcgattc
     4681 ctttgatgct attgaaaaga aaaatccgcg cgttattctc ctcgatcctg ctggaaagca
     4741 gtttgatcag gcttatgctg aagatttggc tcaagaggaa gagctaatct ttatctgtgg
     4801 gcactatgag ggttatgatg agcgcattaa gaccttggta acagatgaga tttccctagg
     4861 cgactatgtc ctcactggtg gagaattggt agctatgacc atgattgatg ctacagttcg
     4921 cctgattcca gaagtgattg gcaaggagtc tagccaccaa gatgatagtt tttcttcagg
     4981 tcttttagaa tatcctcagt acacacgtcc ctatgattat cgaggcatgg tcgtgccaga
     5041 tgtattgatg agtggccacc atgaaaagat tcgtcagtgg cgattgtacg agagtttaaa
     5101 gaaaacctac gagcgcagac cggatttact tgaacattat caactgacag tagaagaaga
     5161 aaaaatgctg gcagaaatca aagaaaacaa agaataaagg agaaacctat gcaagtaatc
     5221 aaacgtaatg gcgaaattgc tgaatttaat ccagataaga tttaccaagc catcttgaag
     5281 gcagcccaaa ctgtttatgt tttgacagat gatttgcgtc aaaatcttgc tcaagtcact
     5341 aagaaggtag ttttggattt acaagaagcc aaggtggaac gtgcgactat cagtatgatt
     5401 caatctatgg ttgaacatcg tttattgggc gcaggttaca ttaccattgc agaacactac
     5461 atttcctatc gtttacaacg tgacttggaa agaagtggtt atggagatca tattgcagtt
     5521 catttacatt ttgaacaaat tcgctaagaa aaaagagtgg gatgaagcaa ctacatctca
     5581 ctctttctta aatctatttt tttgggctgt ttggacagtt gaggggacaa atcgcaggcg
     5641 ttgaatatcg cttatacgga taatccggct cacatttttg gcaaaatttt tcacgataat
     5701 ttgctggcct tgctgatcat atttgatgat atcacctgta aaacttgtct cagacaagat
     5761 aaggtgaaca gcggtttgtt tctggatagc ctcttcaata gtggctgtaa gggagttggt
     5821 ttcagtctgg tcaggttggt catgtccatt taaaaaatca tgtattttat ctagaacttg
     5881 ctggaattta tgtctcatat tggcctccct tcttttatat caatattata taaaattttc
     5941 ctaaaatcta caagatttta cgaataaact aatgaaacta aaaaaggaga agaaaatggc
     6001 agaatttaca tttgaaatcg aagagcactt gttgactctt tctgaaaacg aaaaaggttg
     6061 gaccaaggaa attaaccgtg tgagctttaa tggtgcccct gcaaagtttg atattcgtgc
     6121 ttggagtcca gaccatacta aaatgggcaa agggattact ctctcaaatg aagaatttca
     6181 aacgatggtg gatgccttta aaggcaacta atactcttcg aaaatctctt caaaccgcat
     6241 cagctttgcc ttgccgtatg tatggttact gacttcgtca gtttcatcca caacctcaaa
     6301 acagtgtttt gagcagcctg cggctagctt cctagtttgc tctttgattt tcattgagta
     6361 taagttttca aaataaaaaa aaggatattg agtcatgata actcggtatc cttttttagt
     6421 tagtaaagta agcctgattt ttaaggcgtt gaagtagggg acggctaata aaactaatag
     6481 ccagaagttt gccaaggtct ggaatgataa agggaagaac ccccacaaca agagcttttt
     6541 caaatgccat tccagctagg aaatgcaagc tgagaatccc gccgacaaag acaagggcat
     6601 cacccaagag gtttgcaaga aaaatcttaa caacaccact cttgctgttg gttagagagg
     6661 aagtaagtcc agagtaaacg agataaaacc aaagatagcc tgcagtaggg ccaactaaag
     6721 cctgaaaacc agctccacct cctgcaaaga caggaagacc gatagcacct agaagaagat
     6781 agagtccagc agaaagtaca gcctctctcg gtctaaagac agtagcaatc aagccgattg
     6841 caaagttttg cagagtgaag ggaacaggtc caattggaag actgatttgt gccaaaacag
     6901 caatgagagc agccccaata gcagggatag cataaacgtg agcttttttc aaaatagtta
     6961 acctcttttc taatgtatag taactattat actcatatag gagtcgatgt caaccatttt
     7021 ttaaaaacaa ggtaacaaaa actgtaacag ccgattttcg tgactagtca agttggataa
     7081 tttttttgtt gattcgaaaa ttgtctgtat agataatcct attttattaa taaaaaatat
     7141 actagt
//
LOCUS       DAVMJI010000055         7073 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.056, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000055 DAVMJI010000000
VERSION     DAVMJI010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.056"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            1..465
                     /locus_tag="VYR58_001922"
                     /pseudo
     CDS             1..465
                     /locus_tag="VYR58_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            632..832
                     /locus_tag="VYR58_001923"
     CDS             632..832
                     /locus_tag="VYR58_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623019.1"
                     /translation="MVVSASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            857..1274
                     /locus_tag="VYR58_001924"
                     /pseudo
     CDS             857..1274
                     /locus_tag="VYR58_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1505..2212
                     /gene="ccdA2"
                     /locus_tag="VYR58_001925"
     CDS             1505..2212
                     /gene="ccdA2"
                     /locus_tag="VYR58_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV3623020.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLSVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2223..2780
                     /gene="sdbB"
                     /locus_tag="VYR58_001926"
     CDS             2223..2780
                     /gene="sdbB"
                     /locus_tag="VYR58_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV3623021.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKIVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3154..4545
                     /locus_tag="VYR58_001927"
     CDS             3154..4545
                     /locus_tag="VYR58_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV3623022.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4688..5605
                     /gene="adcAII"
                     /locus_tag="VYR58_001928"
     CDS             4688..5605
                     /gene="adcAII"
                     /locus_tag="VYR58_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV3623023.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5613..>7073
                     /gene="phtD"
                     /locus_tag="VYR58_001929"
     CDS             5613..>7073
                     /gene="phtD"
                     /locus_tag="VYR58_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV3623024.1"
                     /translation="MKINKKYLAGSVAVLSLSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTVRGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKIDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDV"
BASE COUNT         2188 a         1306 c         1471 g         2108 t
ORIGIN      
        1 ttgatagaga tagacttaaa aactatctta ctaataatcc agacgcttat ttgactgaaa
       61 tagcttctga atttggctgt catccaacta ccatccacta tgcgctcaaa gctatgggct
      121 acactcgaaa aaaagaacca cacctactat gaacaaaacc cagaaaaagt agccttattt
      181 cttaagaatt ttaatagttt aaagcaccta gcacctgttt agattgatga aacaggattt
      241 gatacttatt tttatcgaga atatggtcgc tcattaaaag gtcagttaag aagaggcaaa
      301 gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa tggtgaatta
      361 atcgctccaa tgacttacga agagacgatg acgagcgact tttttgaagt atggtttcag
      421 aaatttctct taccaacatt aaccacacca tcggttatta tagtaaaatg gaataagaac
      481 aggacaaatc gatcaggaca atcaaatcaa tttctagcaa tgttttagaa gtccatatgt
      541 actattctag tttcaatata ccataactgc tcctagtcaa cctgcaagtc ctgtcccagc
      601 tccaagctca gctccgactc aagatcctag agtggtagta agcgcttcgg ctagctcaac
      661 gagcacacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga gtcaagagtt
      721 agaccaacgc ttgaaagctt tggcaacagt atctgatccg aaaatcgatg caaccaaggc
      781 tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt aaggtctgca
      841 tactgcagta gagtctgtga agactgcctt ggactctctc aaagatgtga tagcaaatgc
      901 tagcgacagc aagcctacac aggacaagaa ggatgcaaaa caaggaacgg aagatagtaa
      961 ggattcagat aagatgactg aaacaaactc agttccagca ggagtgattg tggtcagtct
     1021 acttgccctc ctaggcgtga ttgccttctg gctaattcgc cgtaagaaag agtcagaaat
     1081 ccagcaatta agcacggaat tgaccaaggt tctaggacag ctagatgcag aaaaaagcgg
     1141 ataaaaaagt ccttgccaaa gcccaaaacc ttctccaaga aacccttgat ttcgtgaaag
     1201 aagaaaatgg ctcagcagag acagaaacta aactagtaga ggagcttaaa gcaatccttg
     1261 acaaactcaa gtaaaacatg atttatgaaa tgtcagacct aaaagacatt ttcgttcaca
     1321 aaagcagcga cgagtaatcc ttgtcgttgc tttttggcta tttttgggga taagatccgc
     1381 cttgactagc aaaagaaaag attggtccaa tagtgcccga tacgattttg cgtagcagaa
     1441 agcttacaaa taaaattgaa tatagtaaaa taggattaga attattaaga aagttggttc
     1501 tttattggaa acgatagtat ttttaatctc tgtttttcta gcaggtgttt tatccttttt
     1561 ttctccttgt atttttcctc ttctgtcagt ctatgctggg attttattgg atgatcaaga
     1621 aagtgcaaaa agcttttctt tgtttgggag aaaggttctc tggtcaggct tgattcgaac
     1681 actttgcttt atcgctggta tctctctcat tttctttatt ctaggctttg gtgctggtta
     1741 ctttggtcat attctctatg caaattggtt tcgatatggc atgggagcta ttattatcat
     1801 tttgggtctt caccagatgg aaatttttca tttgaagaaa ttagaagttc aaaaaagttt
     1861 tacctttaaa aaatcagatt ctaatcgtta ttggtcagct tttttacttg gtattacctt
     1921 tagctttggt tggacacctt gtattggtcc agttttaagt tctgttttag cacttgcggc
     1981 ttctggaggc aatggcgctt ggcaaggagc gatttatact ctcatttaca ctctgggcat
     2041 ggcccttcct ttcttggtat tggcactagc ttcaggtcta gtcatgccat attttagtaa
     2101 aatcaagcgt catatgatgc tactaaagaa aattggtggt ttcctcattg ttttaatggg
     2161 aattttgtta ctattaggac aagtaaatgt tctagctgga atttttgaat aaaggaggac
     2221 aaatgaaaaa agtaatgttt gctggcttaa gtctcttgtc attagttgta ttgatggcct
     2281 gtggtgagga agaaactaaa aagactcaag cagcacaaca gccaaaacaa caaacgactg
     2341 tacaacaaat tgctgttgga aaagatgctc caaacttcac attgcaatcc atggatggca
     2401 aagaagttaa gttatctgat tttaagggta aaaaggttta cttgaagttt tgggcttcat
     2461 ggtgtggtcc atgcaagaaa agtatgccag agttgatgga actagcggcg aaaccagatc
     2521 gtgatttcga aattcttact gtcattgcac caggaattca aggtgaaaaa attgttgagc
     2581 aattcccaca atggttccag gaacaaggat ataaggatat cccagttctt tatgatacca
     2641 aagcaaccac cttccaagct tatcaaattc gaagcattcc tacagaatat ttaattgata
     2701 gccaaggaaa gattggaaag attcaatttg gtgctatcag taatgcggat gcagaagcag
     2761 catttaaaga aatgaactag aatcgataaa atctgattac aagatgtagt cagattttgg
     2821 taacttctaa aactaacttc cagtttccca caacctagct tttagtatga gaaaaacgcg
     2881 tgacatcagt ggaaatccgt cttagactaa cttccactgg ttttcttttt cttgatatat
     2941 aagggttcaa aagcgaaaag actcagaaaa agtgcacgac aaatagccct aaaacagagt
     3001 cgtcttagag taacttccag ttttgggaga gagatggaag ttactttgag aagttacggt
     3061 agtcagattt ttttagaaaa acattttata aatattcaca tatctcctat atttatggta
     3121 aaatagaatc atcagtttat tttggagtca aagatgaata tatttagaac aaagaatgtt
     3181 agtttagata aaacagagat gcataggcat ttgaagttat gggatttgat tttgctgggt
     3241 atcggagcca tggtagggac aggcgtcttt acaatcacag gtactgcagc tgcaacactt
     3301 gctggcccag ccctagtgat ttcaatcgtt atttctgcct tgtgtgtggg attatcagcc
     3361 ctcttttttg cagaatttgc ctcgcgagta cccgctacag gaggtgccta tagttacctc
     3421 tatgctatct taggagaatt ccctgcctgg ttggctggtt ggttaaccat gatggagttc
     3481 atgacagcca tatcaggcgt agcttcgggt tgggcagctt attttaaagg cttgctctct
     3541 caatacggga tagcctttcc tcaggcttta aatggtacct ttaatcctca agcagggaca
     3601 tttgttgatt tattgcctat tcttgtcttg gtcttggtga cttcgcttgt tttactaaat
     3661 gccaaggcag ccttacgctt taattcgatt ctagttattt tgaaattttc cgctttagct
     3721 ctctttgttt tagtaggaat ttggaatatt aagtttgata attggagcaa ttttgctcct
     3781 tacggttttg gacaaatcta tggagctagc actggtatta tggctggtgc gtccttgatg
     3841 ttcttcggtt ttttgggatt tgaatccatc tctatggctg tagatgaagt caagactcct
     3901 caaaaaaata ttcctagagg gattgtctta tcgctttcta tcgtaaccat tctctatgcc
     3961 ttggtgaccc ttgttttgac tggtgtggtt cactatagtc atttaaatgt cgatgatgcc
     4021 gttgcctttg cccttcgtag tgttgggatt agttgggcag ccaactatgt gtcattagtg
     4081 gctatcttga ccttgattac agtttgtatt tcgatgacct atgccctatc gcgtatgatt
     4141 tacagtttag cacgtgacgg cttagtgcct gctgccttta aggaactgac gaagactagc
     4201 aagataccaa agaatgctac tatcttgaca ggtctagctt cagcagtagc agcaggaatg
     4261 ttcccactag ccagtattgc agccttttta aatatttgta ccttagccta cttgatcatg
     4321 ttggcttatg gtctgattcg cttacggaaa gaaaaaggaa tgcccaaagc tggggaattt
     4381 aaaacaccat tggtacctct gttaccaatt ttatcgatca tcatttgttt atccttcatg
     4441 ttacagtata atatgaatac ctggattgct ttcctagttg cgttgttagt aggaagtatt
     4501 atttacttca cttatggcta taagcattct accatagaag aataaagtga aagtctattg
     4561 agttgttgac actcagcaga tttttatatg tgaaagaaat ttcaaatttt ttctaaaaat
     4621 atcttgacag attaaatttt caggagtaga atatttacta gttaattaaa tggttaagga
     4681 gttgttcatg aagaaacaaa atttattttt agtcctgtta agtgtctttc ttttgtgctt
     4741 gggggcttgt ggtcaaaagg aaagtcagac aggaaagggg atgaaaattg tgaccagttt
     4801 ttatcctatc tacgctatgg ttaaggaagt atctggtgac ttgaatgatg ttcggatgat
     4861 tcagtcaagt agtggtattc actcctttga accttcggca aatgatatcg cagccatcta
     4921 tgatgcagat gtctttgttt accattctca tacactcgaa tcttgggcag gaagtctgga
     4981 tccaaatcta aaaaaatcca aagtgaaggt cttagaggct tctgagggaa tgaccttgga
     5041 acgtgtccct ggactagagg atgtggaagc aggggatgga gttgatgaaa aaacgctcta
     5101 tgaccctcac acatggctag atcctgaaaa agctggcgaa gaagctcaga ttatcgctga
     5161 taaactttca gaggtggata gtgagcataa agagacttat caaaaaaatg cgcaagcctt
     5221 tatcaaaaaa gctcaggaat tgactaagaa attccaacca aaatttgaaa aagcgactca
     5281 gaaaacattt gtaacacaac atacagcctt ttcttatcta gcgaagagat ttgggcttaa
     5341 tcaacttggt attgcaggta tctctcctga acaagaacca agtccacgac aactaacaga
     5401 aattcaggaa tttgttaaga cctataaggt taaaacgatt tttacagaaa gtaacgcttc
     5461 ttcaaaagta gctgaaactc ttgtcaaatc aacaggtgtg ggtcttaaaa ctctgaatcc
     5521 tttagagtca gacccacaaa atgacaagac ctatttagaa aatcttgaag aaaatatgag
     5581 tattctagca gaagaattaa agtgaggaaa gaatgaaaat caataaaaaa tatctagcag
     5641 gttcagtggc agtcctttcc ctaagtgttt gttcctatga acttggtcgt caccaagctg
     5701 gtcaggttaa gaaagagtct aatcgagttt cttatataga tggtgatcag gctggtcaaa
     5761 aggcagaaaa tttgacacca gatgaagtca gtaagagaga ggggatcaac gccgaacaaa
     5821 ttgttatcaa gattacggat caaggttatg tgacctctca tggagaccat tatcattact
     5881 ataatggcaa ggttccttat gatgccatca tcagtgaaga acttctcatg aaagatccga
     5941 attatcagtt gaaggattca gacattgtca atgaaatcaa gggtggctat gtgattaagg
     6001 tagacggaaa atactatgtt taccttaaag atgcggccca tgcggacaat attcggacaa
     6061 aagaagagat taaacgtcag aagcaggaac gcagtcataa tcacaactca agagcagata
     6121 atgctgttgc tgcagccaga gcccaaggac gttatacaac ggatgatggg tatatcttca
     6181 atgcttctga tatcattgaa gatactggtg atgcttatat cgttcctcac ggcgaccatt
     6241 accattacat tcctaagagt gatttgtctg ccagtgaatt agctgctgcc caagcctatt
     6301 ggaatgggaa gcagggatct cgtccttctt caagttctag tcataatgca aatccagctc
     6361 aaccaagatt gtcagagaac cacaatctga ctgtcactcc aacttatcat caaaatcaag
     6421 gggaaaacat ttcaagcctt ttacgtgaat tgtatgctaa acccttatca gaacgccatg
     6481 tagaatctga tggccttatt ttcgacccag cgcaaatcac aagtcgaacc gtcagaggtg
     6541 tagctgtccc tcatggtaac cattaccact ttatccctta tgaacaaatg tctgaattgg
     6601 aaaaacgaat tgctcgtatt attccccttc gttatcgttc aaaccattgg gtaccagatt
     6661 caagaccaga acaaccaagt ccacaatcga ctccggaacc tagtccaagt ccgcaacctg
     6721 caccaaatcc tcaaccagct ccaagcaatc caattgatga gaaattggtc aaagaagctg
     6781 ttcgaaaagt aggcgatggt tatgtctttg aggagaatgg agtttctcgt tatatcccag
     6841 ccaaggatct ttcagcagaa acagcagcag gcattgatag caaactggcc aagcaggaaa
     6901 gtttatctca taagctagga gctaagaaaa ttgacctccc atctagtgat cgagaatttt
     6961 acaataaggc ttatgactta ctagcaagaa ttcaccaaga tttacttgat aataaaggtc
     7021 gacaagttga ttttgaggct ttggataacc tgttggaacg actcaaggat gtc
//
LOCUS       DAVMJI010000056         6825 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.057, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000056 DAVMJI010000000
VERSION     DAVMJI010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6825
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.057"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            93..902
                     /locus_tag="VYR58_001930"
     CDS             93..902
                     /locus_tag="VYR58_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV3623025.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            907..1608
                     /locus_tag="VYR58_001931"
     CDS             907..1608
                     /locus_tag="VYR58_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV3623026.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            1633..2550
                     /locus_tag="VYR58_001932"
     CDS             1633..2550
                     /locus_tag="VYR58_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEV3623027.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            2578..4119
                     /locus_tag="VYR58_001933"
     CDS             2578..4119
                     /locus_tag="VYR58_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEV3623028.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            4138..4596
                     /locus_tag="VYR58_001934"
     CDS             4138..4596
                     /locus_tag="VYR58_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV3623029.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            4598..6820
                     /locus_tag="VYR58_001935"
     CDS             4598..6820
                     /locus_tag="VYR58_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV3623030.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
BASE COUNT         2299 a         1036 c         1326 g         2164 t
ORIGIN      
        1 gaaactagtt tctaatttat gaaaaatatt gaaaaaaaaa aaaaagtgtt aaaataaaga
       61 atgtaaacgt ttacttcaac taaggagctc atatgttact gcaaaaagaa ctaattccaa
      121 tgatagaagc taacttacca aatatggcat atgctgaaaa agacattgct aaattcttct
      181 taaaacagca acctctgaat gattattcat ctaaagcatt gtgcgaatac cttaatgtat
      241 ccaaagcaac attgactcga tttgcgaaaa aatgtggttt taaaggtttt agacaattca
      301 ttttcaaata ccaagagatg attcatgaga aagaaaagtt ggcattatat acagaggcaa
      361 cagaaaaagt tttatccgac tatgaggaaa tgttgagaaa aacttacacg gttcttgatg
      421 aagttcaact tgagcgtatt gctgagatga tagaaactgc tgagcgtgta tatctctacg
      481 gtaaaggaag ttctgttctt gctttacaag aaatgaagat gagatttatg cgtctcggag
      541 tgattggtga agtattatca gacgaggata tgattttgtg gagtagctta ctacttaatg
      601 aaaattgcct tgtcattgga gcatccattt caggtcaaac tgatattgta ctagaaggtc
      661 tacaaaaagc tgcagataaa ggcgctaaaa cagttttaat gactacaaga aaatttgacg
      721 aagaagattg tttctttgat gaactattgt tattagcttc gaccgatcat ctctcgtatg
      781 gcaatcgcat atcacctcag tttccaatac ttttaattac agactgctta ttctctaatt
      841 atctggaaag tccagagaga caatattatt acaatcaaac tattatccat aaggaggaat
      901 aataaaatga gccaaatttg gactaaagaa aaatttataa gccaagttca aggtggagtc
      961 attgtttctt gtcaagcttt acctggtgaa gccctttata atgaagaatt tagcttgatg
     1021 ccttttatgg ctaaagcagc tttagaggca ggagcagtgg gcattcgcgc aaattctgtg
     1081 cgtgatatta aagcaattca gaaagtagta gatttaccaa taattggaat tatcaaaagg
     1141 gattatccac ctcaagaacc atatattact gctacgatga aagaagtaga tgaacttgta
     1201 gaatgcggaa caacagtcat tgcatttgat gcaactttaa gaccaagata tgatggctta
     1261 gttgtcagtg aatttatcaa aaaaataaaa gaaaaatatc cgaatcaatt gctgatggcg
     1321 gatgtaagta atttagatga aggtctctat gcatttaaat caggcgttga ttttgttggt
     1381 acaacattat caggttacac aagtacaagt gtacaatcag atgagcctga ttttgaacta
     1441 atgaaaaaat tggctgattt taatattccg gtaattgccg aaggaaaaat tcattatcca
     1501 gaacaattaa aaaaagctta tagtttaggt gttaccagtg tagtcattgg tggagcgatt
     1561 acacgtccaa aagaaattgc tcagcgattt attaatgtca tcaaataaaa aacaatataa
     1621 aggagaaatc tgatgaaaga tttaactaaa tacaaaggcg ttatccctgc attttatgct
     1681 tgctatgatg aaaatggtga aattagccaa gatcgtgtaa aatctctggt acaatatttc
     1741 attgacaaag gtgtaaaagg tatctatgta aatggttctt caggtgaatg tatttaccaa
     1801 agtgtagaag atcgtaaaca aattattgaa gctgttatgg aagttgctaa aggtaaatta
     1861 acagttatca accatattgc atgtaataac acgaaagata gtatcgaatt ggcaaaacat
     1921 tcagaaagtg ttggagtcga tgctattgca gctatcccac ctatttattt caaattgcca
     1981 gagtattcaa tcgcagcata ttggaatgca atgagtgaag ctgcgtcaaa tacagatttt
     2041 attatctata atattccaca attggcaggg gttgcgttga ctggtagttt gtatgcaaca
     2101 atgcgtcaaa atcctcgtgt gattggagtt aaaaattctt ctatgcctgt acaagatatt
     2161 caaatgtttg tagctgcagg tggagaagat tacattgtat tcaatggtcc agatgaacaa
     2221 tatcttggtg gtcgcttgat gggagcagaa gctggtattg gtggtactta tggcgttatg
     2281 ccagatttgt tcttgaaatt ggaaagtttg attcaagaac gagatttaga tacagctaaa
     2341 aaacttcaat atgctatcaa tgaagttatc tataagatga tatcaggtaa ggcaaatatg
     2401 tatgctgtag caaaagaagt tttgcgtcta aatgaaaaac ttgatttagg ttctgttcgt
     2461 caacctttag aagcattggc agaaggtgac ttggaagttg caaaacaagc agcagaactt
     2521 attcaacaag cacgaaaaga atttttataa taaataaaat caatatggag atatgttatg
     2581 ggcacaacag gatttacaat aattgactta attatcttga ttgtttattt acttgcggtg
     2641 ttggttgcag gtatctattt ctctaaaaaa gagatgaaag gaaaagagtt ctttaaagga
     2701 gatggttcgg ttccttggta tgttacttcg gtatccattt ttgccacaat gctcagtccg
     2761 atttccttct tgggactcgc tggtagctct tatgcaggta gctggatttt atggtttgct
     2821 caattaggga tggtagtagc tattccactg acaattcgtt ttatcttacc tatctttgca
     2881 cggatagaca tcgatacggc atatgattac ttggataaac gttttaattc taaagcactt
     2941 cgtattattt cagcactctt gtttattatt tatcaattgg gacgtatgtc tatcattatg
     3001 tacctcccat cagctggttt atcagtattg acaggaattg acatcaatat tttgattatt
     3061 ttgatgggtg tagttgcaat tgtttattct tatactggtg gtctaaaatc cgtattatgg
     3121 acagacttta ttcaaggtgt gattctgatt agtggtgtcg ttttagcttt atttgtactg
     3181 attgctaata ttaaaggtgg ctttggtgca gtagcagaaa cattagcaaa cgggaaattc
     3241 cttgctgcaa atgaaaaact tttcgatcct aacttgcttt caaactccat ctttttaatt
     3301 gtgatgggtt caggctttac aatcttgtct tcctatgctt catctcaaga tttggttcaa
     3361 cgttttacta caacacaaaa tattaagaaa cttaataaga tgttgttcac aaacggtgtt
     3421 ttgtcacttg caactgcaac agtcttttac ttgattggta caggcttgta cgtattctat
     3481 caagtacaaa atgcagatag tgcagctagc aatatccctc aagaccaaat ctttatgtac
     3541 tttattgcat accagttacc agtaggtatc acaggtttga tcttggcagc gatttatgca
     3601 gcatctcaat caactatttc aacaggtttg aactctgttg caacttcatg gacattggat
     3661 attcaagatg tcatttctaa aaatatgtca gacaatcgtc gtacgaaaat tgcacaattc
     3721 gtatctctag cagtaggttt attctcaatt ggtgtttcca ttgtcatggc tcactcagat
     3781 attaaatctg catacgaatg gttcaatagt ttcatgggac ttgtacttgg tctacttggt
     3841 ggtgtattta ttcttggatt tgtttctaaa aaagcaaata aacaaggtgc ttatgcagcg
     3901 ctgattgtat caaccatcgt catggtattt attaaatact tccttcctcc aacagctgtt
     3961 agctactggg catattcatt gatttcaatc tctgtatcag tagtttcagg ttatattgta
     4021 tctgttctta ctggaaataa agtatctgca cctaaatata caacgattca tgatattaca
     4081 gaaattaaag cggattcaag ttgggaagtt cgtcactaat agaaaagaga aaataatatg
     4141 attatttctg aacaatctga ttttaaacga tatgcttctg tcaataaata tttttcaaaa
     4201 gtctgtgatt ttttagaaaa tacaaatttg acagatttag ttgatggaaa aattgatatt
     4261 gacggggaaa atgtttttgc aaattgtatg acttatctag ctgatggagt tccaggagat
     4321 atttttgaaa ctcataagaa atatttagat attcatattg ttgttgaaaa tactgaaaaa
     4381 atggcagtaa cttccccagt tcgtgcccag tcacgtgtac cttttagcga agagaaggat
     4441 attgcttttt acgatagcaa agactatcaa attgttgaat tgcttccagg gaatatgttg
     4501 gtgacttttg aagaagatct tcaccaacca aagattcatt gcaatgatga aacggttaaa
     4561 aaacttgtta tcaaagtttt aaacgaggaa aaataaaatg aaaaaaaata ttaaacaata
     4621 tgtaacctta ggtactgtag tggtattatc agcatttgtt gctaactcag ttgcagctca
     4681 ggagactgaa acttctgaag tatcaacacc aaagttggtg caacctgttg caccaacgac
     4741 tccgatttcg gaagtacaac ctacatcgga taactcttcg gaagttactg tacaacctcg
     4801 aacagttgaa actactgtta aggatccatc ttctacagcg gaagaaactc ctgtcttaga
     4861 aaaaaataat gttactttaa cagggggcgg agaaaatgtt actaaagagt taaaggataa
     4921 atttactagc ggtgacttta ctgtagtgat taagtacaat cagtcaagtg agaaaggctt
     4981 acaagctctg tttggaatat ctaattccaa acccggtcaa caaaatagtt atgtagatgt
     5041 gttccttaga gacaatggtg agttggggat ggaagcgcgt gatacttctt ccaataaaaa
     5101 taacctagta tccagacctg cttcagtttg gggtaagtac aaacaagagg ctgtgactaa
     5161 cactgttgca gtagtagcag attcagtcaa aaaaacatat tctttatacg caaatggtac
     5221 aaaagtagta gaaaagaaag tggataattt cctaaacatc aaggatatta aaggtattga
     5281 ttactatatg cttgggggag tgaaacgtgc aggaaaaacg gcgtttggtt ttaacggaac
     5341 actagaaaat atcaaattct ttaatagtgc attggatgaa gaaactgtta aaaagatgac
     5401 aacaaacgct gttactggac atttaattta tacggctaat gatacaacag gttctaacta
     5461 tttccgtatt ccagttctgt atacttttag caatggtcgg gtattttcaa gcattgacgc
     5521 tcgttacggt ggaactcatg atttcttgaa taaaattaat attgctacaa gttatagtga
     5581 tgataatggt aagacatgga ctaaaccaaa attaacattg gcattcgatg attttgcgcc
     5641 agtaccatta gaatggcctc gtgaagttgg tggacgtgac ttacaaatca gcggtggtgc
     5701 aacctatatt gactctgtta ttgttgaaaa aaagaacaaa caagtactca tgtttgctga
     5761 tgtgatgcct gctggagtaa gttttagaga agcaactaga aaagattcag gttataaaca
     5821 aattgatggt aattattacc ttaaattaag gaaacaaggt gatactgatt acaattatac
     5881 tattcgtgag aatggtactg tatacgacga tcgtaccaac agaccaactg aattttcagt
     5941 agataaaaat ttcggtatta aacaaaatgg taattatttg acggtagagc aatattcggt
     6001 ttcatttgaa aataataaaa agactgaata tcgtaatggg actaaagtcc atatgaatat
     6061 cttctacaaa gatgcattgt ttaaagtagt gccaacgaac tatattgcat atatttctag
     6121 caatgatcat ggcgaatctt ggtctgcacc aactttatta cctcctataa tgggacttaa
     6181 tcggaatgcg ccatatttag gtcctggacg tggaatcatt gaaagctcaa ctggacgtat
     6241 tcttattccg tcttacactg gtaaagagtc tgcgttcatt tatagtgacg ataatggagc
     6301 atcttggaaa gttaaagtag tgccacttcc ttctagttgg tcagcagaag cacaatttgt
     6361 agaattgagt ccaggagtaa ttcaagcata tatgcgtaca aataatggta aaattgcata
     6421 tttaacaagt aaagacgcag gtactacttg gagtgcaccg gaatatttga aatttgtttc
     6481 aaatccaagt tatggaacac aattatcaat catcaattat agccaattga ttgatggtaa
     6541 aaaggctgtc attttaagta ctccaaactc cacaaatggt cgtaaacacg gacaaatttg
     6601 gattggtcta attaatgatg ataatacaat tgattggcgt tatcatcacg acgttgatta
     6661 tagtaactat ggatactcat attcaacatt gacagagtta ccaaatcatg aaattggatt
     6721 gatgtttgaa aaatttgatt catggtctcg taatgaactt catatgaaaa atgttgtacc
     6781 atatataaca tttaagattg aagatctgaa aaagaattaa agctg
//
LOCUS       DAVMJI010000057         6505 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.058, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000057 DAVMJI010000000
VERSION     DAVMJI010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6505
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.058"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            169..1119
                     /locus_tag="VYR58_001936"
     CDS             169..1119
                     /locus_tag="VYR58_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV3623031.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGLTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1296..2303
                     /gene="gap"
                     /locus_tag="VYR58_001937"
     CDS             1296..2303
                     /gene="gap"
                     /locus_tag="VYR58_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV3623032.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2371..3207)
                     /locus_tag="VYR58_001938"
     CDS             complement(2371..3207)
                     /locus_tag="VYR58_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV3623033.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVRWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGKYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3333..5528
                     /locus_tag="VYR58_001939"
     CDS             3333..5528
                     /locus_tag="VYR58_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV3623034.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQSLAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5581..5733
                     /gene="rpmG"
                     /locus_tag="VYR58_001940"
     CDS             5581..5733
                     /gene="rpmG"
                     /locus_tag="VYR58_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV3623035.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5743..5919
                     /gene="secE"
                     /locus_tag="VYR58_001941"
     CDS             5743..5919
                     /gene="secE"
                     /locus_tag="VYR58_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV3623036.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            5974..>6505
                     /gene="nusG"
                     /locus_tag="VYR58_001942"
     CDS             5974..>6505
                     /gene="nusG"
                     /locus_tag="VYR58_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV3623037.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2026 a         1133 c         1410 g         1936 t
ORIGIN      
        1 atatcaaaaa gcacctcaaa aaggtattac caagttgcaa taccttttat gaggctcttt
       61 tgtcttgttc ttgtttcaat tgactatagt tcacggatac agttgggaaa gaagctatta
      121 aatatttgga gagtcctttt gggatgaaca tgtcaaatat tactatagat gggcaagaaa
      181 agatgggcaa gaaatggatc tgagtcaaac gatgcttctt atgctcaagt agtgagtctt
      241 tatgatgata caagtatctc tgttagtaat aatgagacgg acaaagtgtt gactggatcc
      301 ctctatactg aaacaaatga acagggatta acgattccaa gcagtttact aaaaaattgg
      361 aatgaacaga caggaaaaaa tttgacaact aatgatctta ttggcaaatc agtctcagcc
      421 agcattgtag aaagtgctgc cgaaactagt aagattgctc aatttcaaac gaagattgta
      481 cgtgtaatca atgatgaaga tgacatggag gacagcaaca gtttcatgct gtctcatcaa
      541 atggaaacga ttttgaaaga ggctggatta acgaaagctg tatcttattt tatcttggaa
      601 ctcaaagatc catcacagac aaaagtagta acagaagaat tacagaaaaa taagaagtat
      661 actgtgcttt ctcaacagag agttcttgat attgtgatta cctttattcg tgttattcag
      721 ggattattga ttgtgctttc atcacaagct attgtggtag cggcggttat gattggtatc
      781 attatttaca tcaatatcat gcaacgttcc aaggaaatag gtgtcatgaa agcagttggt
      841 tatcagaatc gtggtgtcaa aggaattttt atttacgagg ctatctggat tgtaggcatc
      901 gccttgctgc tggcattttt ggttgcacaa ggggtgggaa gtttggcgaa tgcgattgta
      961 agtcactttt acccatccat cactaaggtt tttgaattaa atcttttatc tgttttagga
     1021 actctagttt tcgctctatt acttggttat gtctcagcct acttcccggc gcgtaagatt
     1081 agtaaaatgg atcctgtaga atcgttacgc tatgaataat aagggattcc ttgatttaca
     1141 gtcttaaaaa gaaactcaca tagaaaaaca atggccatac ttgcaattca actcaaatag
     1201 ttgtataata ggtttgttga aaggtgattt gtagtgattc aagttactct tttcacaata
     1261 aaaatttcat gattttcata aggaggaaat cactaatggt agttaaagtt ggtattaacg
     1321 gtttcggacg tatcggtcgt cttgctttcc gtcgtatcca aaacgtagaa ggtgttgaag
     1381 ttacacgcat caacgacctt acagatccag ttatgcttgc acacttgttg aaatacgaca
     1441 caactcaagg tcgtttcgac ggtactgttg aagttaaaga aggtggattc gaagttaacg
     1501 gtaaattcgt taaagtttct gctgaacgtg atccagagca aatcgactgg gctactgacg
     1561 gtgtagaaat cgttcttgaa gctactggtt tctttgctaa gaaagaagca gctgaaaaac
     1621 accttaaagg tggagctaaa aaagttgtta tcactgctcc tggtggaaac gacgttaaaa
     1681 cagttgtatt caacactaac cacgacgttc ttgacggtac tgaaacagtt atctcaggtg
     1741 cttcatgtac tacaaactgc ttggctccaa tggctaaagc tcttcaagat aactttggtg
     1801 ttgttgaagg attgatgact actatccacg cttacactgg tgaccaaatg atccttgacg
     1861 gaccacaccg tggtggtgac cttcgccgtg ctcgcgctgg tgctgcaaac atcgttccta
     1921 actcaactgg tgctgcaaaa gctatcggtc ttgtaatccc agaattgaat ggtaaacttg
     1981 atggatctgc acaacgcgtt ccaactccaa ctggatcagt tactgaattg gtagcagttc
     2041 ttgaaaagaa cgttactgtt gatgaagtga acgcagctat gaaagcagct tcaaacgaat
     2101 catacggtta cacagaagat ccaatcgtat cttcagatat cgtaggtatg tcttacggtt
     2161 cattgtttga cgcaactcaa actaaagttc ttgacgttga cggtaaacaa ttggttaaag
     2221 ttgtatcatg gtacgacaac gaaatgtcat acactgcaca acttgttcgt actcttgaat
     2281 acttcgcaaa gattgctaaa taattcttga gttgatagaa agcaaggctt tgtggtcttg
     2341 cttttttata tggaaaaatg gatgacacga tcatccattc ttttttaatt ctttttcaaa
     2401 tgtatttgaa agggtagtga aagttagcct ctctaaagta agtgggtggg taaaggaaag
     2461 tcggaaggca tgaagcataa gccggcttgt ctttgattta ctattataga gagggtctcc
     2521 caggatagga agattatgat gcaaaaggtg cacacgaatc tgatgggttc gccctgtctt
     2581 tagcttgcaa tgagccaagg aagtcttgtt tgagaattgc tttaatctgc ttacatgcgt
     2641 ttcagcatat ttcccatttt ttgcatcaac tattcttttt ctacgatcat ggcgatcacg
     2701 tccaattttg tctctgaaaa caagttcttt tctgttgata tttccatcaa ctagagccca
     2761 atattctcta gaaatctctt ttttctccaa taagcgattg agaatgggca ggataaaagg
     2821 atttttggca aagagaacta agccactggt ttccatgtcc agacgatgaa cgacatagca
     2881 ggtttggcca acataggtac tgacatggtt aagaagggca atttcgtttg gttgattacc
     2941 atgcgttttc atcccctctg gtttgtttac aataatcaag tgttgatctt gataaacttc
     3001 ctgcactaag tctgggttgc cccaagggat cgtcttttgg ggataatctt cctcgtcaaa
     3061 agtcaactgg caaacatctc caggatttac gatttcgttc cagcggactt cttcttgatt
     3121 tatcaaaata tgtttcttga ttctcaaaaa atgacggatt tttctaggga tgaggagttg
     3181 ttcctcaagt aattgcttta ccgtcatttg aggtagagag gcgggtaatg taaatgtgaa
     3241 ttgcatacag atattgtaac aaaaaaagcc ctatttggat aggaaatagc taaattcttg
     3301 tcttcctatg atgaagatga taaaataaac gcatgaaatt agataaatta tttgagaaat
     3361 ttctttctct ttttaaaaaa gaaacaagtg aactagagga ctctgattct actatcttac
     3421 gtcgctctcg tagtgatcga aaaaaattag cccaagtagg tccgattcga aaattctggc
     3481 gtcgttatca tctaacaaag attatcctta tactaggttt gagtgcaggc ttgctagttg
     3541 gaatctattt gtttgctgta gccaagtcga ccaatgtcaa tgatttgcaa aatgccttga
     3601 aaactcggac tcttattttt gaccgtgaag aaaaagaggc tggtgccttg tctggtcaaa
     3661 agggaaccta tgttgagctg actgacatca gtaaaaactt gcagaatgct gttattgcga
     3721 cagaagaccg ttctttctat aaaaatgacg ggattaacta tggccgtttc ttcttggcta
     3781 ttgtcactgc tggacgttca ggtggtggct ctaccattac ccaacagctg gctaaaaacg
     3841 cctatttatc gcaggatcaa actgttgaga gaaaagcgaa agaatttttc cttgccttag
     3901 aattaagcaa aaaatatagt aaggagcaaa ttctaaccat gtaccttaac aacgcttatt
     3961 ttggaaatgg tgtgtggggt gtagaagatg cgagtaagaa atactttgga gtttctgcat
     4021 cagaagtgag tctggatcaa gctgcgactc tggcagggat gctcaagggg ccggaactgt
     4081 ataatccctt gaattccgta gaagattcta ctaatcggcg cgatactgtc ttgcagaata
     4141 tggttgcagc aggatatatt gataaaaacc aagaaaccga agctgctgaa gttgatatga
     4201 cttcgcaatt gcacgataag tatgaaggaa aaatctcaga ttaccgttac ccctcttatt
     4261 ttgatgcggt ggttaatgaa gctgtttcca agtataatct aacagaggaa gagattgtca
     4321 ataatggcta ccgcatttac acagagctgg accaaaacta ccaagcaaat atgcagattg
     4381 tttatgaaaa cacatcgcta tttccgaggg cagaggatgg aacgtttgct caatcaggaa
     4441 gtgtagctct cgaaccgaaa acagggggag ttcgtggagt tgtcggtcaa gttgctgaca
     4501 atgataaaac tggattccgg aatttcaact atgcaaccca atcaaagcgt agtcctggtt
     4561 ctacaattaa gcctttagtt gtttatacac cagcagttga agcaggctgg gctttgaata
     4621 agcagttgga taaccatacc atgcagtatg atagctataa ggttgataac tatgcaggga
     4681 tcaaaacaag tcgagaagtt cctatgtatc aatccttggc agaatcgctt aatctacctg
     4741 ctgttgccac tgttaatgat ttgggtgttg acaaggcttt tgaggcaggc gaaaaattcg
     4801 gactcaacat ggaaaaggtc gaccgtgttc ttggtgtcgc cttgggaagc ggtgttgaaa
     4861 ccaaccctct tcaaatggct caagcatacg ctgcctttgc aaatgaaggt ttaatgcctg
     4921 aagctcattt tattagtaga attgaaaatg ctagtggaca agttattgcg agtcataaaa
     4981 attcacaaaa acgggtgatt gataagtctg tagctgacaa gatgaccagt atgatgttgg
     5041 ggactttcac caacggtacc ggtattagtt catcgcctgc agactatgtc atggcaggga
     5101 aaactggaac aactgaagca gttttcaatc cggagtacac aagtgaccag tgggtaattg
     5161 gttatactcc ggatgtagtg attagccact ggcttggctt tccgaccact gatgaaaatc
     5221 actatctagc tggctctact tcaaacggtg cagctcatgt ctttagaaac attgccaata
     5281 ccattttacc ttatacgcca ggaagtacct ttacggttga aaatgcttat aagcaaaatg
     5341 gaattgcacc agccaataca aaaagacaag tacaaaccaa tgataatagc cagacagatg
     5401 ataatttgtc tgatattcga gggcgtgcgc aaagtctagt agatgaggct agccgggcta
     5461 tctcagatgc gaagattaag gaaaaggctc aaacaatatg ggattcgata gtcaatctat
     5521 ttcgctaaga tgcttgtcaa agcctagctt tcttgttata atggataaga tggaggcgtt
     5581 atggcactaa aaaaagcaag cctagcttgt gcggtttgtg gttcgagaaa ctattcaatc
     5641 aagatcagcg gaaaccccaa gcctacacga ctagaagtaa ataaattttg taagcattgt
     5701 ggcaagtaca ctacacacag agaaacgaga taggagagag cgatgcgttt tattggagat
     5761 atttttagac ttcttaaaga cacaacatgg ccaactcgca aggaaagctg gagagatttt
     5821 cgttctatca tggaatacac agctttcttt gtagtaatta tttacatttt tgaccagttg
     5881 attgtttcag gtttgattcg atttattaac attttttaga agattagtgg agttaattac
     5941 actagaaatc ttctatttat gaaaggaaat atcatggata gttttgataa aggatggttt
     6001 gttttacaaa cttattctgg ttatgaaaat aaggtgaaag aaaatctatt acaacgtgca
     6061 caaacctaca atatgttgga taatattcta cgcgttgaaa ttccaacaca aacagtgcaa
     6121 gttgaaaaaa atggaaagag aaaagaagta gaagaaaatc gctttccagg ttatgttctt
     6181 gtagaaatgg tcatgacaga tgaagcttgg tttgttgttc gaaacacacc aaatgttaca
     6241 ggatttgtcg gatcacacgg gaacagatca aaaccaactc cattattgga acaagaaatt
     6301 cgtgacattt tggtatctat gggacaaact gttcaagaat ttgatttcga tgttgagatt
     6361 ggtcaaactg tacgtattat tgatggtgct tttgcagact acactggtaa gattacagaa
     6421 attgataata acaaagtgaa aatgattatc tctatgtttg gtaatgacac agttgcagaa
     6481 gtaaacctaa accaaatcgc agaat
//
LOCUS       DAVMJI010000058         6170 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.059, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000058 DAVMJI010000000
VERSION     DAVMJI010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6170
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.059"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            16..1041
                     /locus_tag="VYR58_001943"
     CDS             16..1041
                     /locus_tag="VYR58_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV3623038.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1031..2038
                     /locus_tag="VYR58_001944"
     CDS             1031..2038
                     /locus_tag="VYR58_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV3623039.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2038..3045
                     /locus_tag="VYR58_001945"
     CDS             2038..3045
                     /locus_tag="VYR58_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV3623040.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSITAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3045..3839
                     /locus_tag="VYR58_001946"
     CDS             3045..3839
                     /locus_tag="VYR58_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3623041.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            4227..4652
                     /locus_tag="VYR58_001947"
     CDS             4227..4652
                     /locus_tag="VYR58_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV3623042.1"
                     /translation="MPKRYLLDGKTPRISVTNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            4708..5025
                     /locus_tag="VYR58_001948"
     CDS             4708..5025
                     /locus_tag="VYR58_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEV3623043.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            5339..>6170
                     /locus_tag="VYR58_001949"
     CDS             5339..>6170
                     /locus_tag="VYR58_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEV3623044.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEQWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     G"
BASE COUNT         2429 a          851 c         1048 g         1842 t
ORIGIN      
        1 gtttaaggag tttttatgaa aaacaaattt tttctaatag ctattttagc tatgtgtata
       61 gtttttagcg cttgttcttc taattctgtt aaaaatgaag aaaatacttc taaagagcat
      121 gcgcctgata aaatagtttt agatcatgct ttcggtcaaa ctatattaga taaaaaacct
      181 gaaagagttg caactattgc ttggggaaat catgatgtag cattagcttt aggaatagtt
      241 cctgttggat tttcaaaagc aaattacggt gtaagtgctg ataaaggagt tttaccatgg
      301 acagaagaaa aaatcaaaga actaaatggt aaagctaacc tatttgacga tttggatgga
      361 cttaactttg aagcaatatc aaattctaaa ccagatgtta tcttagcagg ttattctggt
      421 ataactaaag aagattatga cactctatca aaaattgctc ctgtagcagc atacaaatct
      481 aaaccttggc aaactttatg gagagatatg attaaaattg attcaaaagc cttaggtatg
      541 gaaaaagaag gtgatgagtt aatcaaaaat actgaagctc gtatatccaa agaattagaa
      601 aaacatccag aaatcaaagg aaaaatcaaa ggaaaaaaag tattatttac tatgattaat
      661 gctgcagata catcaaaatt ctggatttat actagcaaag atccaagagc aaattattta
      721 acagatttag gtctagtttt ccctgaatca ttaaaagaat ttgagagtga agatagtttt
      781 gcaaaggaaa tttctgcaga agaagcaaat aagataaatg atgctgatgt aatcataact
      841 tatggtgatg ataaaactct tgaagcttta caaaaagatc ctcttttagg taaaataaat
      901 gcaattaaaa atggtgccgt tgctgtaatt ccagataata caccgttagc agcctcatgc
      961 actccaacac cactttcaat aaactatact attgaagaat acctaaatct tttaggaaat
     1021 gcatgcaaaa atgcgaaata aaaaacaaat aaacctaggc ataatttttg taatctgcct
     1081 aggtcttctt attacaatat ttttgtcatt aaagcttgga acaaaagaaa ttaatatcag
     1141 agatttttta gcagcttttg gaatgggtaa tacaaatgat gattttatta aatcaattat
     1201 atataaaaga atacctagaa ctatttttgc aattttagca ggttctagtc ttgccataag
     1261 cggtgtattg atgcaatcag ttactagaaa cccaatagct gatccaggta tactcggtat
     1321 aaacacagga gcaagtctta gtgtagtaat tggtctttct tttttaggaa tttcatcaag
     1381 cataagccat ataagttttg caatcattgg tggcttagta agtgcaattt ttgtatacgc
     1441 gattgctgta agcggaaaag caggccttac ccctataaaa cttgccttat caggaacttg
     1501 tgttagtatg gctttaagca gttttgtaag ttttttaatt ttaccgaata ataacgtctt
     1561 agacaaattt agattttggc aaataggtag ccttggagca gctacattat cttctatatc
     1621 tacactacta ccttttataa ttttaggtca cttgatagct atatttattt catcagattt
     1681 aaacgcttta gctatgggtg atgaaatggc tgttggtctt ggagttaatg ttaataggat
     1741 aagatcactt gcaataattg caagtgtgct tttatgttca agtattactg caattggtgg
     1801 acctattggc ttcgtaggtc ttatagttcc tcacttttgt ggcttattta taagcaaaga
     1861 tatacgcaca atgaccattt cttcatcttt tataggtgca gagctcttgc ttatatgtga
     1921 tataatcggc cgtatgttag gtaaaccagg tgaaattgaa gtagggataa ttactgcaat
     1981 aatcgggggt ccagtactta tttatgtaac tatgaaaaat agaggggtta ataactaatg
     2041 caaaatttaa ttataggtat tcaaaaaaga aaaaatagaa taacactatt ttcctcacta
     2101 tttttattaa taataatcag tctatcattt ttcattttac ttatcggaga tgaaagttat
     2161 tctttttcaa ctttgattaa agtcttaaat agtgaaactg ttcctggagc tagtttttcg
     2221 attatggaaa ttagattacc aaaattatta gcaggaatta tagctggctg gtcttttgga
     2281 ttggcaggat ttatctttca aactatgtta agaaatcctc ttgcaagtcc tgatataatc
     2341 ggtgtcacaa gttcttcatc tattacagcg gtcttttgca tattggtatt aaaaacaaat
     2401 agtttaacta ctggaattat ttcaataact tgtggactaa catcatcttt aatattattt
     2461 ttactagcta aaaaagatgg tttttcagca gcaagactga taatattagg tattggtttt
     2521 caagctgtca caagagcagg cacctcattt ttattgttga aagtagcaag atatgaatta
     2581 caagaagtta tgagatggct cagtggctct ttatctttta caaagttaga tgacatacct
     2641 cttgttctaa tagtaagtat tattgctact atattagttt tattttttaa taaaagacta
     2701 gaaattattg aacttggtga agaaatagca atcggacttg gagcaaatcc cgagctttca
     2761 aggcttgttt taattttttg cgctgtatct ttaactgctt tttctacttc aattacagga
     2821 ccaatagctt gtatatcttt tttagctggt cccatagcct taaatattgg caagaaaaga
     2881 agcccaatat tagctggatt ggttggaatt ttactagttt tgttatcaga catattctct
     2941 caaaatattt taccagctag atatccagta ggtgttgtaa ctggcttgtt aggttcacca
     3001 tacttaatat acttactaat aaaaatgaac aggaggaata tataatgaaa ggtctgtggt
     3061 caaataatct tacctgcggt tatgatgaaa aaataatctt ggaaaatata aatataaaaa
     3121 tacctgaaga aaaaatatca gttattattg ggtcaaatgg ttgtgggaaa tcaacactca
     3181 ttaaaacctt gtctcgactt ataaagccat tagagggaga agtattgctt gataataaat
     3241 caattaattc ttataaagaa aaagatttag caaaacacat agctatatta cctcaatctc
     3301 caataatccc tgaatcaata acagtagctg atcttgtaag ccgtggtcgt ttcccctaca
     3361 gaaagccttt taagagtctt ggaaaagatg accttgaaat aataaacaga tcaatggtta
     3421 aggccaatgt tgaagatcta gcaaataacc tagttgaaga actttctggg ggtcaaaggc
     3481 aaagagtatg gatagctcta gccctagccc aagatacaag tatcctactt ttagatgagc
     3541 caactactta cttggatatc tcatatcaaa tagaactatt agacctcttg actgatctaa
     3601 accaaaaata taagacaacc atttgcatga ttttgcacga tataaatcta acagcaagat
     3661 acgctgatta cctatttgca attaaagaag gtaaacttgt tgcagaggga aagcctgaag
     3721 atatactaaa tgataaacta gttaaagata tctttaatct tgaagcaaaa attatacgtg
     3781 accctatttc caattcgcct ctaatgattc ctattggcaa gcaccatgtt agctcttaat
     3841 aattgaatat tggaattcat ttaaaagtcg caaattttga actgaccctc aaaagttagg
     3901 ccaaaaaact aactaaagga ggtcagtttt ttaatggcaa atacagcaca gaatttaaga
     3961 taaaattagt aaaagaatat catgaatgaa aaataggata tagagaataa cagcaatatt
     4021 aaaaagatca ggactgataa taaacaaaaa gaaagtacaa cgactagttc aaaagctaaa
     4081 acttcaagta aaaagttatt caagaaaatc tagaaaatac tcatcctaca aaggacaggt
     4141 aggaaaaata tcagacaaca aaataaaaag aaatatttat taccgaaaaa aaggggaaat
     4201 cgagtcaagt accaacaggc tcatctattc caaaaagata tttactcgat ggaaaaactc
     4261 ctagaattag tgttacaaat attgacaatg gtatcttagg ttactacgaa gatatagatg
     4321 ataaaaatta tagagttttt gaaaatttta tatctgtttc atttttagga gcagtctttt
     4381 atcataaata taaagcaagc ctagatatga aaattcattg tttaaaatta aaaaataaag
     4441 aattgaataa agaagtagca ttctatttaa cttcaattat taggcaagct ttaaaaaata
     4501 ctgaatataa agatcaaata tctagcacag tattgccaga tatcaaaatt aaattaccga
     4561 tagacagtag aggtactcca gactggaatt acatggaaag atatatagaa gacttaaaat
     4621 taaaatgcaa tatagcaaat tataatattt aaaataagaa cgattagaaa taaaaatcta
     4681 gtcgtttttt attttaagaa aggatacatg atggcaagta aaagattaag tattgaagaa
     4741 cagattgaaa agaaagaaga aagcattaag caattacaaa atcaaaaaag acagttgaag
     4801 aaaaaactta atgaacaaga aagaaaagca agaaacaaaa gacttataga aaaaggtgca
     4861 gtgtttgaaa gtatttttga agaaagtatt gatttaacaa aagatgaatt ttataagtta
     4921 ataaaaacgt taaatgatga agaaataaga ttaaacataa tggaaatttt agaagaaaga
     4981 atagatgata atgtagaaaa atcatctaaa gatgaaataa cataattgtc ccttggttac
     5041 aagggcgcaa ttatacaccc taaagggtgc ttgcgtcctg cggagtcaaa cccttgcagg
     5101 gagcaacaac cattcgcttt ttaaaagtca agggtaaata aactcgctaa ggctcgccct
     5161 tgacttttaa aatttgaaat gaaagtaaca attaagccga catactgaaa caacaaaaat
     5221 taattcagta gtcggctttt tttattctat catttcaaaa cgctcattca caaagaggat
     5281 ataaaaaaac tattaagcct ccacctaaaa caacaaagaa agaaaggaag tgataaaaat
     5341 ggcagacagt tttcattttt cagtaaacat aatatcaaga ggaaaaggca aaagtgcagt
     5401 agcaagtgca gcatatataa gtggagaaaa aataaaaaat gaatgggacg gagtaaccca
     5461 tgactacaca agaaaagaaa aaatattagt aaaaaatata atattgcctg atcatatacc
     5521 aaaagaattt aatgataggt ctaccttatg gaataaagta gaaatggcag aaaaaaattc
     5581 taatgcacaa ctagcaagac aattcataat aggactacca aaagagttat ctttaagtga
     5641 aaataaaaac ctggttgaaa gatatataaa agaaaattta acatcacaag gaatgatagt
     5701 agattatgca attcatgatg agagtcaaga taaaaatgga aatatccatt gtcatataat
     5761 gaccataatg cgaccaataa acgaaaaagg agagttctta gccaagtcaa aaaaagaata
     5821 tatcctagat gaaaaaggag aaaaagtatt aaacaaaaat ggaaaaccaa agacaagaaa
     5881 agtagaacta acaacctgga acgatacagg caatgtagaa caatggagag aaaatttttc
     5941 agatctttgt aacaaatatt tagaaagagc aggagcagaa aaaagagtag accataggag
     6001 ttttaaaaga caaaattcag attatctacc gacaatccat ttaggatcag cagcaagtgc
     6061 aatggaaaga aagggaatag aaactgacaa gggaaactat aatagagaaa taagaaaata
     6121 taatcaactt gtaaaaacaa taaaagaaga gataaaaaca ttaaagggtt
//
LOCUS       DAVMJI010000059         5641 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.061, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000059 DAVMJI010000000
VERSION     DAVMJI010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.061"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            93..281
                     /locus_tag="VYR58_001950"
     CDS             93..281
                     /locus_tag="VYR58_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV3623045.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            343..1101
                     /locus_tag="VYR58_001951"
     CDS             343..1101
                     /locus_tag="VYR58_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV3623046.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            1159..2013
                     /locus_tag="VYR58_001952"
     CDS             1159..2013
                     /locus_tag="VYR58_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV3623047.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EHEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            2125..3009
                     /locus_tag="VYR58_001953"
     CDS             2125..3009
                     /locus_tag="VYR58_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV3623048.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            3172..4911
                     /locus_tag="VYR58_001954"
     CDS             3172..4911
                     /locus_tag="VYR58_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV3623049.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIWKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            5186..5641
                     /locus_tag="VYR58_001955"
     CDS             5186..5641
                     /locus_tag="VYR58_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623050.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSENLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         1894 a          844 c         1194 g         1709 t
ORIGIN      
        1 taaaaatcct ctccactttt aaactaatgt attataaaag ccagttgaca caagtgttac
       61 acctgtgata gaattaactt gaggtgatga aaatggcaac cgataaaaat agaataatga
      121 ttagcttgga tgataaaaat ctagagaaac ttgaaaattt agtagaagat gctagagata
      181 gaaggggaat gcgactaaca aagtcccagg ttattgaatt actcctaaat accgttgatt
      241 atttcgatga tattatgggg gctatttact caaaaaaata agagcaaaat tgctattatt
      301 ttttacaaat tggtgtaaca ctagtgatat aggagtgatg aaatggttgt ttatattaga
      361 caaagtaaat taccaagtga ggtttcaatt aataaataca atgctcaagt aggtgcctac
      421 ttacaaggag aagaagctgt tttatatcaa tctttttctg aaataaaaga gttaacaagt
      481 gaagatatag ttgtagatta tataatggag actagagcat tactaaaaat gatgggctta
      541 aacgttccgg ttcatgacta tcctattgag cttaaagagt tttatggtcg aaagatttat
      601 gctggtattt taggagagat tgtgaatata cctgataatt ggggaaaatt tattaagcct
      661 aaagctggtt caaaagtctt tactggaaga gttgttaatg gaacccatga tttaataggt
      721 attggtctac ctttcgacta tcctatatgg attagtgagg ttgtagaatt catagctgaa
      781 tggcgttgtt ttgtgttaga tggtcgcgta ttagatgttc gaccctatac aggtgattat
      841 catgcacaat ttgatgcaag tgtaattgat gaagcgatat catgttggaa agatgcgcca
      901 atagcttatg gactagatat cggtgttact cgcgatggca gaacacttgt tgttgaagta
      961 aatgatggtt atgcattggg aaattatggc ctatctcctt taaaatcaat caattttcat
     1021 agagctaggt ggaaagaaat ggtaaaaccc tattttgaaa aaaatgaaat ttttaaaatc
     1081 caacaggatg ttgttttcta aaataaatat ggtatataac caatataaaa agcatcaaaa
     1141 tgaacaagga ggaatctgat gcttggagca attattggag atattgtcgg ttctgtttac
     1201 gaatggaaca atatcaaaac aaaggacttt cctttatttc ggaaggactg cttttttaca
     1261 gatgacacgg ttatgacctg tgctgttgca gaagcaatta tgaatggtgg acaaaaagac
     1321 gatttcattg acgcgatgaa gaaatatggc agaatgtatc cgaatgctga ttacggtgct
     1381 cggtttaatg catggctaaa cagcgataac cgtgagcctt ataatagctt tgggaatgga
     1441 tcagctatgc gtatttctcc atgtgcttgg atcatggact gtggttttta tgcgaaaact
     1501 ggtatgtggc catcatctag aggacttacg agtctttctg cagaggtaac tcataatcat
     1561 ccagaaggtg tcaaaggcgc tatggctaca gctgatgcta tctttctatg tcgtttttac
     1621 tttggtggtt attgtagaga gcacgagcaa tcaattaacg acaatcctac agagtgtaaa
     1681 agacgaatta aggattatat agaaaaagaa tacgattaca atctatctca aactttagat
     1741 gaaatccgtc ctaactatcg ttttaacgaa acatgtcagg aaactgtccc tcaagccatt
     1801 atcgcctttc ttgaaagtag agacttcgaa gatgcgataa gaaatgccat ctcacttggt
     1861 ggcgacagtg atactctcgc agcaatcact tgtagcatag cagaggcagc ttacggtatt
     1921 cctgattgga tcaaggataa ggcctattct tacttggatg aacccttaaa ggatgtagtt
     1981 aggcgatggg aaaatagaat aaaagcgtat taatctccag tacgtcagat ttctcttttc
     2041 tgtattttca ttgtataata ggattacatt tacttgcata cgacgaaatg taaacatttc
     2101 tgtttaaaat taaggataaa atcaatgaaa aaagcaatgg taattatcaa ccctacttct
     2161 ggtggcgaga aggctttgga ttacaaagaa aagctggaga ataaagcaaa agaatacttt
     2221 gaatatgttg aaaccaaaat taccgaaaaa gcgctggatg caacacattt tgctgaagaa
     2281 gcttctcgtg agcagtatga tgcagtggtt gtgtttggtg gagatggaac tgtcaatgaa
     2341 gtcatttcag gtattgatga gagagactac attcctaagt tagggattat cccaggcggt
     2401 acgggtaacc tcattacaaa acttttggaa atcaatcaag acatcgatgg cgcaattgac
     2461 gaactggatt ttgatttaac caataagatt gatatcggta aagcaaatga caactatttt
     2521 ggttatatct ttagtatcgg ttctctgcct gaggcgattc acaatgttga aatagaggac
     2581 aaaacaaaat tcggtatttt aacctatgct gtaaatacca tgaagtctgt catgacagat
     2641 caggtcttta acattaaggt tgagacagaa aatggaaatt atgttggtga agctagccat
     2701 gttttggtcc ttttgacaaa ttacttcgct gataagaaaa tctttgaaga aaacaaggac
     2761 ggctatgcca acattttgat tctgaaagat gcctctatat tctccaaatt atccgtcatt
     2821 cctgatttat taaaagggga tgttgtcgca aatgataata tcgagtatat caaagcgcgt
     2881 aatattaaaa tctcttcaga tagtgaattg gagtcagatg ttgacggaga taaatcagat
     2941 aacctacctg tagaaatcaa agtcctagct cagcgagtag aagtattttc aaaaccgaaa
     3001 gaggattagt atatagagaa agcctttttt aaggcttttt gtatacttta aaagatagtt
     3061 cctttaacaa cggacattcc ttgcaaatag tttacaaaaa tagtatactg gatttattga
     3121 gtttgaaaac gtttgcgtaa aatttgaatg aatactttag gagacaaatt gatggaattg
     3181 agtgctattt accataggcc tgagtcggag tatgcctatc tttataagga taagaaactc
     3241 catattcgaa ttcgaactaa gaaaggggac attgaaagca tcaacttgca ctatggggac
     3301 ccttttatct ttatggagga gttttatcag gatacaaaag aaatggtcaa gataacttct
     3361 ggtaccttat ttgaccattg gcaggttgaa gtgtcagttg actttgcacg tatccagtat
     3421 ctctttgagc tcagagatac agaaggtcaa aatattttgt atggcgataa agggtgtgtg
     3481 gaaaattctc tagaaaatct tcatgcaatt gggaatggat ttaagttgcc ttatcttcat
     3541 gagattgatg cctgcaaggt tcctgactgg gtttcaaata cggtatggta tcagatattt
     3601 cctgaaagat ttgccaatgg caatgctcta ttaaacccag aagggacttt agactgggat
     3661 tcatctgtca cacctaagag cgatgatttc tttggtggtg atttacaggg gattattgat
     3721 catatggatt acttgcaaga cttgggtatt actggactat atctttgtcc catctttgaa
     3781 tctacaagca atcacaagta caatacgaca gattactttg aaattgaccg tcattttgga
     3841 gacaaggaga cctttcggga actggtggat caagcgcatc atcgtggcat gaaagtcatg
     3901 ctggatgcgg tatttaatca tattggttcg caatctcttc aatggaaaaa tgtcgtcaaa
     3961 aatggtgaac agtctgctta taaggattgg ttccatattc aacaattccc agtgacaact
     4021 gaaaagctag ttaataagag agacttaccc tatcatgttt ttggtttcga ggactatatg
     4081 cctaagctaa atacagccaa tccagaggtc aagaattatc ttttaaaggt tgcgacttat
     4141 tggattgaag agtttaatat cgatgcttgg cgtttggatg tggctaatga gattgaccat
     4201 cagttctgga aggattttcg taaggcagtt ttagctaaaa atcctgatct ttatatccta
     4261 ggagaagtct ggcatacatc tcagccttgg ctaaatggag atgagttcca tgccgtcatg
     4321 aattatcctt tatctgatag tatcaaggac tatttcttac gaggaattaa gaagacagac
     4381 cagttcatcg atgaaatcaa tggagagtct atgtattaca agcagcagat ttcagaggtc
     4441 atgtttaatc tcttggattc acatgataca gagcgaatcc tgtggacggc caatgaagat
     4501 gttcaactgg ttaaatcagc cttagccttt ctctttttac aaaaaggaac accgtgcatt
     4561 tattacggaa ccgagctagc cttgactgga ggaccagatc cagattgtcg tcgttgtatg
     4621 ccttgggaac gtgtatcaag tgacaatgat atgctgaact ttatgaagag gctgattaag
     4681 atttggaaat acgcgtcagt aatcatttcg catggcaagt atagccttca agaaatcaaa
     4741 tctgatctag tagctctgga atggaaatac gaaggacgga tcctcaaagc aatattcaac
     4801 caatcaacag aagattatct tttagagaaa gaagcagtag cactagcaag caattgccaa
     4861 gaattggaga atcagcttgt catctctcca gatggatttg tgattttcta aaaactagtt
     4921 gatgaagatt atggtacatt tcatatctta tatagtataa taaggctagt tactaaactt
     4981 gtaaaggaga acttaaatga attgtagagg acatgaaaca agacaaagaa ttgttagaga
     5041 ttttgaagtt tagcctaaag cacatattaa gctgttagca aatcaacaaa aacatagtga
     5101 tgcaggagca actattgaag atgaatatta tgtatttatc gctgagagta aaattgatgg
     5161 caagaaggaa gttattcagt gttgcatggg tgcggcaagg gattttttag aactaattaa
     5221 tcacaaaggg ctacctcttt ttaatccgct tgtaggtgat tctcatgtaa ataatagaca
     5281 agaatatgac aatacaggga gtgaaaattt acaacctgaa aagtggaatg aaactgcaaa
     5341 gcagctttat aatgctataa tgtggttgat tattttatgg aatgctaagc cggatacacc
     5401 tttatttaat tttaaagacg aagtaattaa gtataaaaca tatgagcctt ttgaaagcag
     5461 tataaaaaga gtaaatacta ctataaagaa tggtagtaaa gggaaaactc tgactgagat
     5521 gattaatggc tacagagcgg ataacgatat tagagatgaa atttgtaact ttaatattct
     5581 gaaaaataaa attcgtgata tgaaagacca acaaggaaat acaatggaat cttactttta
     5641 g
//
LOCUS       DAVMJI010000060         5627 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.062, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000060 DAVMJI010000000
VERSION     DAVMJI010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5627
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.062"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..1109
                     /locus_tag="VYR58_001956"
     CDS             <1..1109
                     /locus_tag="VYR58_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV3623051.1"
                     /translation="VNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQELG
                     SDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKAM
                     VDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSWK
                     KLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLEY
                     SDDCYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQE
                     EDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEKL
                     LNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            1266..2156
                     /locus_tag="VYR58_001957"
     CDS             1266..2156
                     /locus_tag="VYR58_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV3623052.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            2181..2504
                     /locus_tag="VYR58_001958"
     CDS             2181..2504
                     /locus_tag="VYR58_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623053.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            2494..4485
                     /locus_tag="VYR58_001959"
     CDS             2494..4485
                     /locus_tag="VYR58_001959"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEV3623054.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            4501..4977
                     /locus_tag="VYR58_001960"
     CDS             4501..4977
                     /locus_tag="VYR58_001960"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEV3623055.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            5011..5592
                     /locus_tag="VYR58_001961"
     CDS             5011..5592
                     /locus_tag="VYR58_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623056.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
BASE COUNT         1928 a          747 c         1131 g         1821 t
ORIGIN      
        1 tggtaaatta cggtattgtt ggagctggat attttggagc tgatttagct cgctcaatga
       61 acaaaattga agatgcaaaa gtggttgcgg tatttgaccc aaatcatgga gaagaagttg
      121 ctcaagagtt gggatcagat gtttgtgcaa gtttagatga acttgtagca cgtgaagata
      181 ttgattgtgt gatcgtagct tcacctagct accttcaccg tgaaccagtt gtgaaagctg
      241 ctcaacatgg caaacacgta ttttgtgaaa agccaattgc attgtcttat gaagattgta
      301 aagccatggt tgacgcatgt aaagaaaata atgtcatctt tatggctggt cacatcatga
      361 acttctttaa cggtgtacac catgctaaag aattgattac tcaaggtaaa atcggtaaag
      421 ttctttattg ccatgctgct cgtacaggtt gggaagaaca acaaccaact gtatcatgga
      481 agaaacttcg ttctcaatct ggaggacatt tgtaccacca tattcatgaa ttagattgca
      541 ttcagtttat catgggagga cttcctgaaa aagcgacaat ggtaggaggc aatgtatatc
      601 ataaaggtga aaactttggt gatgaagatg atatgctcat tgtaaactta gaatactctg
      661 atgattgtta tgctgttttg gaatatggta atgctttccg ttggggtgaa cactacgtct
      721 tgattcaagg aactgaagga gctatcaaac ttgacttgtt caatactggc ggtactcttc
      781 gtgttaaagg tgaaggagaa tcacacttct tagttcatga aactcaagag gaagatgatg
      841 atcgtacagc tatctatacc ggtcgtggta tggatggagc aattgcgtac ggtaaaccag
      901 gagtacgttg cccattatgg ttgcaaacat gtattgataa agaaatggaa tatctacatg
      961 acatcattaa aggtggagaa attacagaag aatttgaaaa acttctcaat ggtgtagctg
     1021 ctttagaatc aatcgctacc gctgatgcat gtactttatc agttaaagaa gatcgaaaag
     1081 taagtctttc agaaatcaca aatgcttaac ttttgtaaaa cagaatagta aattcttgtc
     1141 attatataat ttctaaagtt ctgtgataca actcattgaa taaagaaata gagatgggac
     1201 tgggataatg cccagtccca ttttttatca aaaagtaatg agatcaaaaa tgtgggagtg
     1261 ttgaaatgaa gattataggt atcgatattg gcggaacaac aattaaggca gatttatacg
     1321 atgagtttgg aacgagtttg aatcatttca aagagataga aacaattatt gactatgatt
     1381 tgggaacgaa tcagatatta aatcaggtct gtgatttaat tggtgagtat actttaaatc
     1441 attcaattga tggtgttggg atttccactg ctggagttgt taatgctaat actggagaaa
     1501 tcatctatgc aggctataca ataccagggt atatcggagt aaactttact gccgaaatag
     1561 aaaaacgttt tgggttgtat acttttgttg aaaatgatgt taattgtgct gcattaggtg
     1621 aattgtggaa gggacaagcc aaagataaga aaaatgtagt aatggttact attggaacag
     1681 gtataggagg cagtattatt gtcaacggac aaattgttaa cggatttaac tatactgctg
     1741 gtgaagtagg ttatattcct gtaggtaatt cggattggca aagtaaagcc tcaacaaccg
     1801 cattgattca tttatatcaa aaaaagagct tgaaaactaa tcaaactgga cgtactttct
     1861 tcactgattt aagatctgga gataaagttg ctgaagaaac ttttgaaatt tttgtagaaa
     1921 atctaacaaa aggtttatta acgatttctt atctacttaa tccagaaatt ctcatattag
     1981 gaggtgggat tctggatagt aaggatattt tgttacctga aattcaaagt tctttagcta
     2041 aaaatgcaat ggataatagg tttttaccta aaaatcttgt ggcagctaca ttaggaaatg
     2101 aagctggtcg tataggagct gtaaaaaatt tcttagatag aatttctaat aaatagtatg
     2161 taagataagg aggtgtcaca atgactaact ctgtattttc gacaatgcaa gatattgaga
     2221 atgttgcaac cgatattata aaatcatatg ataatgagat ttatacttat aaagctgttt
     2281 cccaagaaga attggaaaaa ctagaaaaaa gttatgatga aaaaagtcac gaagaattag
     2341 tttcaataga aagcaattta gaaatgaaac aacagaacct tattgatgag gttaataaaa
     2401 caatcaagga aaatgatgca aatattcagt atatttcatc aagtaggaga ggagaatttg
     2461 tagaaaaaat tattggtagg gtggtagaaa aatatggcca ttagtcagat gaaaagaatc
     2521 tctctactat tttctaaaag tagtcttgat gatgttttaa aaactattca agaactagag
     2581 tcagtgcagt tccgtgattt aaaggttcag gataattggt cagaagctct agaaaaagat
     2641 gaagttgtat ttccaactat tcaaattttt catacttcta attccaatca tggggttatt
     2701 gagggaaatg atgccttgac ttatttgatg aatcaacaac aacatttaga agcaactgta
     2761 gagaaattac aagaatacct accgaaagaa aacacgttta aattattgca gcaacctccg
     2821 ataactacct cttatgaaga attagagaaa tttggtaaag ctaatgttgc tgagggtgtt
     2881 cttaaaaaag tgaatcatca aattaacaga gttcatgaat tagaaagaca cattcaaagt
     2941 aataatgagg aaatagagcg attaataaag tgggaaaaat tagaaattgt tcctgcgaat
     3001 ttagaacaat tttctttctg taaaggaaaa gtcggaacaa ttccaaggac tgaagataat
     3061 cgcttataca atagtctttt agaaaacaat attgaagttc aagaaatatt ttctaatgat
     3121 agagagtacg gtgttgttgt tttctatcag tctagttact ctatagattt tgatgaatac
     3181 ttatttgaac catttgatta ttctagaaag gaattaccga agcagcgagt agtagattta
     3241 gatcaagaaa acatgcagtt aataactgaa aaagagaata ttatcgcatc gttgcaagat
     3301 tcaaagaaat atttgataga tttacaatgg caaatagact atattttatc tatctatgct
     3361 cgtcaaatct ctaagaataa ctttttgtgc actccgcatc tagttgcatt agaaggatgg
     3421 atagaagaaa ctcgtatttt atattttata aaagttatgg atgagcattt tggacattct
     3481 atttatattt atgaatcgga aacattgacg gataatcaag atgaaatacc tatcaaatta
     3541 acgaatcatt ctttaattga accatttgaa ttattgacag aaatgtatgc tctgcccaaa
     3601 tattatgaga aagatcctac acctgtatta gcaccatttt actttacatt ttttggaatg
     3661 atggttgctg atttaggcta tggtttacta ttgtttttag gaacaatgtt agcattaaaa
     3721 atttttcatc taccttcagc aactaagaga tttttaaaat tctttaatat attaggggta
     3781 gccgttgcaa tttggggtgg aatctatggc tcattttttg gatatgagtt gccatttcat
     3841 ctgatatcta caacctctga tgttatgact atattagtag tgtcagttgt gtttgggttt
     3901 attacagtat ttgcaggttt gttagcttca ggactacaaa aagtaagaat gaagaaatat
     3961 gcagaagcat ataattcagg atttgcgtgg tgtgttattc tgcttggctt gttatttatt
     4021 gctgttggaa tgttgatgcc tgatatgaga ccgttatttg tattagggaa atgggtatct
     4081 atttttaatg ctgtggggat tttgattgtt tctattattc aaaccaaaag cttgtcaggt
     4141 attggagcag gattgtttaa tctatataac atttcatctt atataggtga tttagttagt
     4201 ttcactcgat tgatggcatt aggattatct ggagcaagta tagcatcagc tttcaattta
     4261 attgttggtt tgtttccggg aatattggct aaactgacaa ttggattagt attattcatt
     4321 cttttacatg cgatcaatat ttttctatcg ttactatcag gatatgttca tggagcacgt
     4381 ctgatatttg ttgaattttt tggtaagttt tatgagggtg gaggaaaacc atttcaacct
     4441 ttgaaggctt ctgagaaata tattaaggtt attacaaaga attaatggag gatatatata
     4501 atggaacatt tagcaactta tttttcaacc tatggaggag ctttcttcgc tgcattggga
     4561 attgtattgg cggttggatt aagcggtatg gggtctgctt atggagttgg taaggctggg
     4621 caatctgccg cagctttact gaaagaacag cctgaaaagt ttgcctcagc tttgatattg
     4681 caattattgc ccggaacaca aggattatat ggttttgtta ttggaatttt aatttggttg
     4741 caattaactc cagaacttcc tttagaaaaa ggcgttgctt atttctttgt agctcttcca
     4801 attgctattg taggatactt ttcagctaag catcaaggaa atgtagcagt agcgggaatg
     4861 caaatcttgg ctaaaagacc aaaagaattc atgaagggag caattttagc tgccatggta
     4921 gaaacctatg caattcttgc ttttgtcgta tcattcattt tgacccttcg tgtataagaa
     4981 ataaatttgc aattcaaagg aggtgtctaa atgagcaatt tagaaaactt acgagagtct
     5041 gttattgaac aagctcatga aaaagggcgt atgaaattat tggattccaa aaagaagatt
     5101 gatgatgaat ttgaaatgca aaagtcgctc attataaaga aaaaagaagc tgaacatgaa
     5161 cgaaagttaa aagaattgca acagaaatat caaataattt ttcaacaatt aaaaaataag
     5221 gaacgccaat caacgttagt atcaaaacag aaaatattaa aagaactttt tcaatctgct
     5281 ttactagaaa tggaatcttg gagtgcagat aaagaaatgg agttcatcta tcgaattctg
     5341 gaacgatatt cacaacaaga ggtcatagta acctttgggg aacggacttt agctaaattc
     5401 aatttggaac aattagagaa attgaaattc tcttttccaa attatttatt tagtgaacaa
     5461 cctatctcaa atgaatcagg cttacttatt tcaataggta aaattgatga taactatttg
     5521 tataaaacat taattggatc gatttctaag gaagaaagtt caagtatcgc aaatcaaatt
     5581 tttatcaatt aaggatgaaa ttggttaatc cttcttagaa atttgga
//
LOCUS       DAVMJI010000061         5100 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.063, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000061 DAVMJI010000000
VERSION     DAVMJI010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5100
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.063"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            233..1778
                     /locus_tag="VYR58_001962"
     rRNA            233..1778
                     /locus_tag="VYR58_001962"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1830..1902
                     /locus_tag="VYR58_001963"
     tRNA            1830..1902
                     /locus_tag="VYR58_001963"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1863..1865,aa:Ala,seq:tgc)
     gene            2027..4928
                     /locus_tag="VYR58_001964"
     rRNA            2027..4928
                     /locus_tag="VYR58_001964"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5005..>5100
                     /gene="rrf"
                     /locus_tag="VYR58_001965"
     rRNA            5005..>5100
                     /gene="rrf"
                     /locus_tag="VYR58_001965"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1448 a         1032 c         1491 g         1129 t
ORIGIN      
        1 cacttgatga aaaaaagttt aaaaaagctt aaaaatcttc aaaaaagtgt tgacaagtga
       61 aagtggctgt gatatactaa tatagttgtc gcttgagaga agcaagtgac aaagaccttt
      121 gaaaactgaa caagacgaac caatgtgcag ggcgctacaa cataagttgt agtactgaac
      181 aatgaaaaaa caataaatct gtcagtgaca gaaatgagta agaactcaaa cttttaatga
      241 gagtttgatc ctggctcagg acgaacgctg gcggcgtgcc taatacatgc aagtagaacg
      301 ctgaaggagg agcttgcttc tctggatgag ttgcgaacgg gtgagtaacg cgtaggtaac
      361 ctgcctggta gcgggggata actattggaa acgatagcta ataccgcata agagtggatg
      421 ttgcatgaca tttgcttaaa aggtgcactt gcatcactac cagatggacc tgcgttgtat
      481 tagctagttg gtggggtaac ggctcaccaa ggcgacgata catagccgac ctgagagggt
      541 gatcggccac actgggactg agacacggcc cagactccta cgggaggcag cagtagggaa
      601 tcttcggcaa tggacggaag tctgaccgag caacgccgcg tgagtgaaga aggttttcgg
      661 atcgtaaagc tctgttgtaa gagaagaacg agtgtgagag tggaaagttc acactgtgac
      721 ggtatcttac cagaaaggga cggctaacta cgtgccagca gccgcggtaa tacgtaggtc
      781 ccgagcgttg tccggattta ttgggcgtaa agcgagcgca ggcggttaga taagtctgaa
      841 gttaaaggct gtggcttaac catagtaggc tttggaaact gtttaacttg agtgcaagag
      901 gggagagtgg aattccatgt gtagcggtga aatgcgtaga tatatggagg aacaccggtg
      961 gcgaaagcgg ctctctggct tgtaactgac gctgaggctc gaaagcgtgg ggagcaaaca
     1021 ggattagata ccctggtagt ccacgctgta aacgatgagt gctaggtgtt agaccctttc
     1081 cggggtttag tgccgtagct aacgcattaa gcactccgcc tggggagtac gaccgcaagg
     1141 ttgaaactca aaggaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg
     1201 aagcaacgcg aagaacctta ccaggtcttg acatccctct gaccgctcta gagatagagc
     1261 tttccttcgg gacagaggtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat
     1321 gttgggttaa gtcccgcaac gagcgcaacc cctattgtta gttgccatca ttcagttggg
     1381 cactctagcg agactgccgg taataaaccg gaggaaggtg gggatgacgt caaatcatca
     1441 tgccccttat gacctgggct acacacgtgc tacaatggct ggtacaacga gtcgcaagcc
     1501 ggtgacggca agctaatctc ttaaagccag tctcagttcg gattgtaggc tgcaactcgc
     1561 ctacatgaag tcggaatcgc tagtaatcgc ggatcagcac gccgcggtga atacgttccc
     1621 gggccttgta cacaccgccc gtcacaccac gagagtttgt aacacccgaa gtcggtgagg
     1681 taaccgtaag gagccagccg cctaaggtgg gatagatgat tggggtgaag tcgtaacaag
     1741 gtagccgtat cggaaggtgc ggctggatca cctcctttct aaggataagg aactgcgcat
     1801 tggtcttgtt tagtcttgag aggtcttgtg gggccttagc tcagctggga gagcgcctgc
     1861 tttgcacgca ggaggtcagc ggttcgatcc cgctaggctc cattggtgag agatcaccaa
     1921 gtaatgcaca ttgaaaattg aatatctata tcaaatagta acaagaaaat aaaccgaaaa
     1981 cgctgtagta ttaataagag tttatgactg aaaggtcaga aaataaggtt aagttaataa
     2041 gggcgcacgg tggatgcctt ggcactagga gccgacgaag gacgtgacaa acgacgatat
     2101 gccttgggta gctgtaagta agcgatgatc cagggatttc cgaatggggg aacccaacag
     2161 gtaatacctg ttacctacat ctgttaagga tgtgaggagg aagacgcagt gaactgaaac
     2221 atctaagtag ctgcaggaag agaaagcaaa agcgattgcc ttagtagcgg cgagcgaaac
     2281 ggcagaaggg caaaccgaag agtttactct tcggggttgt aggactgcaa tgtggactca
     2341 aagattatag aagaatgatt tgggaagatc agccaaagag agtaatagcc tcgtatttaa
     2401 aatagtcttt gtacttagca gtatcctgag tacggcggga cacgtgaaat cccgtcggaa
     2461 tctgggagga ccatctccca accctaaata ctccctagtg accgatagtg aaccagtacc
     2521 gtgagggaaa ggtgaaaagc accccgggag gggagtgaaa tagaacctga aaccgtgtgc
     2581 ctacaacaag ttcgagcccg ttaatgggtg agagcgtgcc ttttgtagaa tgaaccggcg
     2641 agttacgtta tgatgcgagg ttaagttgaa gagacggagc cgtagggaaa ccgagtctga
     2701 atagggcgcc ttagtatcat gacgtagacc cgaaaccatg tgacctaccc atgagcaggt
     2761 tgaaggtgcg gtaagacgca ctggaggacc gaaccagggc acgttgaaaa gtgcttggat
     2821 gacttgtggg tagcggagaa attccaaacg aacttggaga tagctggttc tctccgaaat
     2881 agctttaggg ctagcgtcga cattagagat tcttggaggt agagcactgt ttgggtgagg
     2941 ggtccatccc ggattaccaa tctcagataa actccgaatg ccaatgaatt atggtcggca
     3001 gtcagactgc gagtgctaag atccgtagtc gaaagggaaa cagcccagac caccagctaa
     3061 ggtcccaaaa taattgttaa gtggaaaagg atgtggggtt gcacagacaa ctaggatgtt
     3121 agcttagaag cagctattca ttcaaagagt gcgtaatagc tcactagtcg agtgaccctg
     3181 cgccgaaaat gtaccggggc taaaacaatt taccgaagct gtggatacct ttataggtat
     3241 ggtaggagag cgttctatgt gtgatgaagg tataccgtga ggagtgctgg aacgcataga
     3301 agtgagaatg ccggtatgag tagcgaaaga caggtgagaa tcctgtccac cgtaagacta
     3361 aggtttccag gggaaggctc gtccgccctg ggttagtcgg gacctaagga gagaccgaaa
     3421 ggtgtatccg atggacaaca ggttgatatt cctgtactag agtatgtagt gatggaggga
     3481 cgcagtaggc taactaaagc agacgattgg aagagtctgt ctaagcagtg aggtgtgaat
     3541 tgagtcaaat gcttaattct ataacattga gctgtgatgg ggagcgaagt ttagtagcga
     3601 agttagtgac gtcacactgc caagaaaagc ttctagcgtt taaacatact ctacccgtac
     3661 cgcaaaccga cacaggtagt cgaggcgagt agcctcaggt gagcgagaga actctcgtta
     3721 aggaactcgg caaaatgacc ccgtaacttc gggagaaggg gtgctgactt aaagtcagcc
     3781 gcagtgaata ggcccaagca actgtttatc aaaaacacag ctctctgcta aatcgtaaga
     3841 tgatgtatag ggggtgacgc ctgcccggtg ctggaaggtt aagaggagtg cttagcgtaa
     3901 gcgaaggtat gaattgaagc cccagtaaac ggcggccgta actataacgg tcctaaggta
     3961 gcgaaattcc ttgtcgggta agttccgacc cgcacgaaag gcgtaatgat ttgggcactg
     4021 tctcaacgag agactcggtg aaattttagt acctgtgaag atgcaggtta cccgcgacag
     4081 gacggaaaga ccccatggag ctttactgca gtttgatatt gagtgtctgt accacatgta
     4141 caggataggt aggagtctaa gagatcggga cgccagtttc gaaggagacg ctgttgggat
     4201 actacccttg tgttatggcc actctaaccc agataggtga tccctatcgg agacagtgtc
     4261 tgacgggcag tttgactggg gcggtcgcct cctaaaaggt aacggaggcg cccaaaggtt
     4321 ccctcagaat ggttggaaat cattcgcaga gtgtaaaggt ataagggagc ttgactgcga
     4381 gagctacaac tcgagcaggg acgaaagtcg ggcttagtga tccggtggtt ccgtatggaa
     4441 gggccatcgc tcaacggata aaagctaccc tggggataac aggcttatct cccccaagag
     4501 ttcacatcga cggggaggtt tggcacctcg atgtcggctc gtcgcatcct ggggctgtag
     4561 tcggtcccaa gggttgggct gttcgcccat taaagcggca cgcgagctgg gttcagaacg
     4621 tcgtgagaca gttcggtccc tatccgtcgc gggcgtagga aatttgagag gatctgctcc
     4681 tagtacgaga ggaccagagt ggacttaccg ctggtgtacc agttgtcttg ccaaaggcat
     4741 cgctgggtag ctatgtaggg aagggataaa cgctgaaagc atctaagtgt gaaacccacc
     4801 tcaagatgag atttcccatg attatatatc agtaagagcc ctgagagatg atcaggtaga
     4861 taggttagaa gtggaagtgt ggcgacacat gtagcggact aatactaata gctcgaggac
     4921 ttatccaaag taactgagaa tatgaaagcg aacggttttc ttaagttgaa tagatattca
     4981 attttgagta ggtattactc agagttaagt gacgatagcc taggagatac acctgtaccc
     5041 atgccgaaca cagaagttaa gccctagaac gccggaagta gttgggggtt gccccctgtg
//
LOCUS       DAVMJI010000062         5040 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.064, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000062 DAVMJI010000000
VERSION     DAVMJI010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5040
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.064"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            70..1329
                     /locus_tag="VYR58_001966"
     CDS             70..1329
                     /locus_tag="VYR58_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV3623057.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHIHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1405..1540
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1579..2079
                     /locus_tag="VYR58_001967"
     CDS             1579..2079
                     /locus_tag="VYR58_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV3623058.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2155..2523
                     /gene="rplL"
                     /locus_tag="VYR58_001968"
     CDS             2155..2523
                     /gene="rplL"
                     /locus_tag="VYR58_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV3623059.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2710..2880
                     /locus_tag="VYR58_001969"
     CDS             2710..2880
                     /locus_tag="VYR58_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623060.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2880..3128
                     /locus_tag="VYR58_001970"
                     /pseudo
     CDS             2880..3128
                     /locus_tag="VYR58_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3142..3482
                     /locus_tag="VYR58_001971"
                     /pseudo
     CDS             3142..3482
                     /locus_tag="VYR58_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3475..3855
                     /locus_tag="VYR58_001972"
     CDS             3475..3855
                     /locus_tag="VYR58_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV3623061.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3868..4011
                     /locus_tag="VYR58_001973"
     CDS             3868..4011
                     /locus_tag="VYR58_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623062.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4104..4691
                     /locus_tag="VYR58_001974"
     CDS             4104..4691
                     /locus_tag="VYR58_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3623063.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            4893..5030
                     /locus_tag="VYR58_001975"
     CDS             4893..5030
                     /locus_tag="VYR58_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV3623064.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT         1598 a          843 c         1075 g         1524 t
ORIGIN      
        1 acctacggca aagtgaatct gaagtggttt gaagagagta caacttgtct tttagaaaag
       61 gagcctataa tgaaagtctt tcagcatgta aatatcgtga cttgtgatca agatttccat
      121 gtttatcttg atggaatctt agcagtcaag gattctcaaa tcgtctatgt cggtcaagat
      181 aagccagcgt ttttagagca agctgagcag attatagact atcagggagc ttggattatg
      241 cctggtttgg tcaattgtca catccattct gcaatgacag gtctgagagg gatccgagat
      301 gacagcaatc tccatgaatg gctcaatgac tatatttggc cagcagaatc tgagtttact
      361 cccgacatga ctaccaatgc ggtcaaagaa gccctgacag agatgctcca gtcaggaaca
      421 acaaccttta acgatatgta taatcccaat ggtgtggata tccagcaaat ttatcaggtg
      481 gtgaaaactt ccaagatgcg ttgttatttt tctccgactc tcttttcttc agagacagaa
      541 acaactgctg agactataag tagaactcga tccatcatag acgaaatctt aaaatataaa
      601 aatccaaatt tcaaggttat ggtagcacct cattctccgt atagctgcag tagagacttg
      661 ctggaagcga gtttggaaat ggcaaaagag ctaaatattc cgctccatgt ccatgtggcg
      721 gagaccaagg aggagtcagg aattatcctc aaacgatacg gcaaacgccc ccttgctttt
      781 cttgaagaac tgggttattt agatcatccg tccgtatttg ctcacggggt cgaattaaac
      841 gagagagaaa ttgaacgctt ggcatcttct caagtggcta tcgcccacaa tcctatcagt
      901 aacctcaaac tggcatcagg aattgctcca attatccagc tccaaaaagc gggagtagca
      961 gtcggaattg cgactgactc ggttgcttcc aataacaatc tagatatgtt tgaggaagga
     1021 aggactgcag ctcttcttca gaagatgaaa agtggggatg ccagccagtt tccaatcgaa
     1081 acagctctca aggtactgac aatcgaaggg gctaaggtcc ttggaatgga aaatcagata
     1141 ggaagtctgg aagtcggcaa gcaagcagat tttctggtca ttcaaccaca agggaaaatt
     1201 catctccaac ctcaggaaaa tatgctgtct cacctggttt atgcagttaa atctagtgat
     1261 gtagatgatg tttatatcgc cggagaacag gttgttaagc aaggtcaagt cctgacagta
     1321 gaactttaaa agaaaaatta cgaaaaattt taaaaaaagt ttgcaaaaat cttgcattct
     1381 ttttttgact atgctatact tatatacggt ttaaaaaaac tgcctaagac agtaggggag
     1441 ctcgactcat aaatatccta ccgaggacaa aacgtatcat gtaaaaagaa gcgtattgta
     1501 ctttcgtgtc taggtttggg cgcgtttttc tttttgaaaa attccccaag caaaataatt
     1561 acggaggtga acacactaat gagtgaagca attattgcta aaaaagcgga actagttgac
     1621 gtagtagctg aaaaaatgaa agctgctgca tctatcgtcg ttgtagacgc tcgtggtttg
     1681 acagttgagc aagatacagt tcttcgtcgt gagcttcgtg gaagcgaagt tgagtataaa
     1741 gttattaaaa actcaatctt gcgtcgtgca gctgaaaaag ctggtcttga agatcttgca
     1801 tctgtatttg ttggaccatc tgcagtagca ttttctaatg aagatgttat cgcaccagcg
     1861 aaaatcttga acgacttttc taaaaacgct gaagcacttg aaattaaagg tggtgcaatc
     1921 gaaggcgctg tcgcatctaa agaagagatt cttgcacttg caactcttcc aaaccgcgaa
     1981 ggacttcttt ctatgctcct ttctgtactt caagcgccag tgcgcaacgt tgctcttgca
     2041 gtcaaagcgg ttgcagaaag caaagaagac gcggcttaat cttaagctat acagcgtagc
     2101 ctagctacga aaaaaactat tataaaattt aaaacttatt tggaggaaat aacaatggca
     2161 ttgaacattg aaaacattat tgctgaaatt aaagaagctt caatccttga attgaacgac
     2221 cttgtaaaag ctatcgaaga agaatttggt gtaactgcag ctgctcctgt agctgttgct
     2281 gcagctgatg cagctgatgc tggtgctgct aaagattcat tcgacgttga attgacatct
     2341 gcaggcgaca aaaaagttgg cgttatcaaa gttgtacgtg aaatcactgg tcttggtctt
     2401 aaagaagcta aagaacttgt tgacggtgca ccagcacttg ttaaagaagg cgttgcaact
     2461 gcagaagctg aagaaatcaa agctaaattg gaagaagctg gagcttcagt tactcttaaa
     2521 taatagagta tcgcaatttg attgcggaat ccctatttac cagtctttga gagcgataag
     2581 cgattgatag aaactgataa attgatttgg tttcctgcca aaaattcttt ggcaggattt
     2641 ttgttttaat aaactttcgg gggtagacac tagattgtct accccttttt ttgtgtttcg
     2701 gaggtaatta tgcaaaagga aggacagtca tcacgtcaat tcgtgaagag tcatctcatg
     2761 actatcatgg gagttgatat tgtaaaagca actcagttag ttgatgaaat ggaacaagta
     2821 ggtttaatcc gatttgatga atttggaaat gttggaattt tagtcttgga gggacaataa
     2881 tgaagcgtat taccgctaat caatatcaga catcagagcg ttattataag ctccccaaac
     2941 ttttatttga gagtgaacgg tataagaata tgaaactgga ggttaaggtg gtttactcag
     3001 ttttaaaaga tcggttggag ttgtctttga gcaaaggttg gattgatgag gatggggcta
     3061 tttatttgat ttattccaat tcaaatttga tggcactttt aggctgttca aagtcaaaat
     3121 tactctccat gtgagtttga agtgacattt ttagatgatt accataaaaa acataactac
     3181 ccactatttt acgaatccta tcttcaaaac gttatggaat tccttgaaag tcaagacata
     3241 aagaatgggg ttgatgcctt tgtagatgat catcaaaatc tcgtttttgt tttatatgga
     3301 caaggctatc gagccgaggg aaaagaggga atacttacaa cccaagtaac tgtaaaagct
     3361 tatgatgaag acaagaaacc gattaacttc gcaaatttat tagattcctt aatttattag
     3421 attccttaat cgtgtcagaa tatcaaatgg aaccgaatct ttgggaggtc tcccatgatt
     3481 gatctctatc taagtaaaaa tagacaaaga aatcaacttc ttttagattt cttccaaaac
     3541 tatggcatag aggtatcttg tcattcagtt tctgaaatga caaaggacaa attaattgag
     3601 atgatgagct attcttcaga ttgttttgag tttttatctc ccaatttatt acgatttaag
     3661 aaccgtgaca atctaagatt aacggatttc gttgagataa ttttaaaaaa tcctgaacta
     3721 accatcagac ttcctcttgc ggtttcaaat aagcgagttt atccaagtct gaatttggaa
     3781 gaggctagag ctctattgcc aagagatacg aaacaattga tttacatggc gcaaacacat
     3841 tatttatcta actaaaggag aagcaatatg gctgaacgat tttgggagaa cttgtccatt
     3901 attttggctg aaagaaatat cagctggatt gagttaacca gaaaaatgtt tgcgggagag
     3961 tttcactatc caagtgaatt gaatcgtttg tatcaaaaga ttcgccacta gaagatggaa
     4021 caatgaatgc ctcaaagtcc atgggtagaa aggattgtgc aggtattaga tttagattat
     4081 gaagatttat ttcggaggta actatgaaaa gaataattcc agtttatata ttccaacaag
     4141 taaatgtcct attggtatct ctatacttat tgaaatttct ttgtatcggt gagttaacta
     4201 tactacagat tctctatggt tcgtcactca tttctttttt atggatgtat ggccaacgca
     4261 aacaagctca taaggtaaat atgaaatcta ggatgaaatg gcttggtatt ggattcgtta
     4321 gcctactgat tataagtcta tgttttagcc taatccatgc gcaagaaagc acgaatcaag
     4381 caaacttaat tggacttcaa catcaagttc cttggttttc atttttattg tttttaatca
     4441 atgcgagtat ggttgaagaa tttctgtata gagaaatttt atggaacttg gttagaaaat
     4501 tagatattcg agttgctttg acaagtgttt tatttgcctt agcacatcat ccaggaacca
     4561 ttatagcttg gtgtttgtat gtatcgctgg ggatgttttt agggcttgta cgctacaaat
     4621 tggacttatg gggcagtatg gggctacatt tggtgtggag cctactagtt tatagtttgc
     4681 tgctttttta aaataggtaa cctgattttt aggtaacttc taaaactaac ttccagtttt
     4741 gggagagaga tggaagttac tttgaaaagt tacggaaaca ttattttcta cgtgacaaca
     4801 ttgtatcatt gcttgcattt tactgctgga gagagtataa tgaaggtgga taaagcactt
     4861 aatcccaaaa atttaaatag gaggagttag ctatggcaga agaagtatta aatcttcaat
     4921 tagtatctgt tcaagttgac gaaacagatg aagttgatgg aatgcgattt agtacattca
     4981 gtacaaaccg ttgcggtaac tggagtgctt ttagttggga aaattgttaa ttcatttaaa
//
LOCUS       DAVMJI010000063         5024 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.065, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000063 DAVMJI010000000
VERSION     DAVMJI010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5024
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.065"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..387
                     /locus_tag="VYR58_001976"
     CDS             <1..387
                     /locus_tag="VYR58_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV3623065.1"
                     /translation="NKSHGDILQLLSDEGSISAKEFIYIVENQEIFVWFNKINPSLDS
                     IFSTYELKMQDATISSSELEFLCDLLLYKTLDQGRYNVEGPLVLARYLLGCEFEVKNL
                     RMIISALQNTIPFESIKERIRPHYGS"
     gene            377..697
                     /locus_tag="VYR58_001977"
     CDS             377..697
                     /locus_tag="VYR58_001977"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEV3623066.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            760..2535
                     /locus_tag="VYR58_001978"
     CDS             760..2535
                     /locus_tag="VYR58_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEV3623067.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTISIGQKVSTGDILGTVKETEVVNHKIMVPYGISGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQALGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDDKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSENERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIIEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIQLILETGGL"
     gene            2536..3921
                     /locus_tag="VYR58_001979"
     CDS             2536..3921
                     /locus_tag="VYR58_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEV3623068.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVKFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            3944..4555
                     /locus_tag="VYR58_001980"
     CDS             3944..4555
                     /locus_tag="VYR58_001980"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEV3623069.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKAFAVAKSLKNSLMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            4631..4834
                     /locus_tag="VYR58_001981"
     CDS             4631..4834
                     /locus_tag="VYR58_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3623070.1"
                     /translation="MTVSGYLFQNFGLLDNENVSTDLDLGLISRKCNFKEKDKLKKDV
                     LARVGLTHIHLEQKIYELSGGEA"
BASE COUNT         1678 a          730 c         1046 g         1570 t
ORIGIN      
        1 aataagagtc atggggatat tttacaatta ctttcagatg aaggaagtat ttctgctaaa
       61 gaatttatat acattgtaga aaatcaagaa atatttgtgt ggttcaataa aataaatcca
      121 agcttagatt caatcttttc aacttatgaa ttgaagatgc aggacgcaac aatttcatct
      181 tctgagttag aatttttatg tgatttacta ttgtataaaa ctttagatca aggaaggtac
      241 aatgtagagg ggccgttagt tcttgctaga tatttattgg gatgtgagtt tgaagtaaag
      301 aatctcagaa tgatcatatc agctcttcaa aatacaattc cctttgaatc aataaaagaa
      361 aggatacgcc cacattatgg aagctaataa gtataaaatt ggcataattg gtagccgtga
      421 tattatttta ccatttagca tgattgggtt tgatatattt cctgcctacc aagaacaaga
      481 agctataaat acactaagaa aattagctca atctgattat ggtgtcattt atatcactga
      541 agacattgct tcaatgatat tagatacaat tcgccattat gattcccaag ttgtgcctgc
      601 tattatttta ttaccgactc ataaacaagg tttaaattta ggattaaaac gtatagagga
      661 taatgtagag aaagcagtag gacacaatat tttataataa tgtacaaaat tgtctgtaat
      721 attattctat aatttttgga cttagtaagg agaataactt tgactcaagg gaagattata
      781 aaagtatcgg gacctctagt tattgcatca ggtatgcagg aggctaatat tcaagatatt
      841 tgccgtgtag gtaagctagg gttaatcggt gaaattattg aaatgagaag agatcaggca
      901 tctatccaag tctatgaaga aacatctggt cttggtccgg gagaacctgt tgttacaact
      961 ggagaacctc tctcggttga attagggcct ggattgattt ctcaaatgtt tgatggcata
     1021 caacgcccat tagatcgatt taaattggct actcataatg attttctagt tcgtggggta
     1081 gaagttccaa gtttggatag agatattaag tggcattttg attccactat atcaattggt
     1141 caaaaagtga gtacgggtga tattcttgga actgtcaagg aaaccgaagt agttaatcat
     1201 aaaattatgg ttccttatgg aatatctggc gaagtcgttt ctattgcctc tggcgatttt
     1261 acaattgatg aagttgtata tgaaataaaa aaattggacg gtagtttcta taaaggaaca
     1321 cttatgcaaa aatggcctgt ccgcaaggcg cgtcctgttt ctaaacgttt aatcccagaa
     1381 gaaccattaa tcacaggtca acgagttatt gatacattct ttccagtaac caaaggggga
     1441 gcagcagctg ttcctggacc gtttggagca ggaaagacag ttgtacaaca ccaagtagct
     1501 aaatttgcca atgttgatat tgttatttat gtcggttgtg gagaacgtgg aaatgaaatg
     1561 acggatgtac tgaatgagtt tcctgagttg attgacccta atacaggaca atcaattatg
     1621 caacggacag ttctgattgc taatacttca aatatgcctg ttgctgctcg tgaggcttca
     1681 atttatacag gaattaccat ggctgagtat tttcgtgata tgggctactc tgtcgccatt
     1741 atggctgatt cgacttcacg ttgggcagaa gcgctacgtg aaatgtcagg acgtctagaa
     1801 gaaatgcctg gtgatgaggg ttatcctgct tatcttggaa gtcgtatcgc tgaatattat
     1861 gaaagagcgg gacgttctca ggctctaggg cttccagaac gtgaaggaac gattactgct
     1921 attggagctg tatcgccacc cggtggagat atttcagaac cagttactca aaacacttta
     1981 cggattgtga aagttttttg ggggcttgat gctccgttgg cacagcgacg tcattttcct
     2041 gcaattaact ggcttacctc ttattcactc tataaagaca gtgtgggaac ttatatagat
     2101 gataaagaga agacagattg gaatagtaaa ataactcgtg cgatgaacta cttacaacgg
     2161 gaatctagtt tagaggaaat tgttcgtctt gttggaattg attctctgtc tgaaaatgaa
     2221 cgactaacga tggaaattgc taaacaaatt agagaagatt atttgcaaca gaacgctttt
     2281 gattcggtag atacattcac ttcgtttgca aaacaagaag caatgttaag taatatccta
     2341 acttttgctg atcaggcaaa tcatgcttta gagttgggtt cttactttac agagattata
     2401 gaaggtaccg tggcagttcg agaccgtatg gcgagaagta aatatgtttc agaagataga
     2461 ttagatgaaa tcaaaattat ttcaaatgag attacacatc aaattcaatt gatattagaa
     2521 acaggaggtc tataaatgag tgttataaaa gaatatagaa ctgctagtga agttgttggg
     2581 cctcttatga ttgttgaaca agttaataat gtgtcttaca atgagttagt tgaaattcaa
     2641 cttcataatg gagaaattcg tcgtggacaa gttttagaga tccacgaaga taaagcaatg
     2701 gttcagcttt ttgaaggatc tagtggaata aatttagaaa agtctaaaat tcgttttgct
     2761 ggtcatgcac tagaattggc tgtatctgag gatatggttg gtagaatttt taatgggatg
     2821 ggaaaaccaa ttgatggtgg accagattta attccagaga aatatttaga tattgatggt
     2881 caagctatta atcctgtatc tagagattat ccagatgaat ttattcagac agggatctcc
     2941 tctattgatc atttgaatac tcttgtacgt ggtcaaaaat taccagtatt ttcaggttcg
     3001 ggcttacctc ataatgaatt agcagctcag atagcaagac aagcgactgt tttaaattct
     3061 gatgaaaatt ttgcggttgt atttgcagca atgggtatta cttttgaaga agctgagttc
     3121 tttatggaag aactcagaaa aacaggagcg atcgatcgtt cagtcttatt tatgaacttg
     3181 gcaaatgatc ctgcaattga gcgtattgca actccccgca ttgctttaac tgcggcagag
     3241 tatctagctt ttgaaaaaga tatgcatgtt ctagttatca tgacggatat gactaactat
     3301 tgtgaagcgt tacgtgaagt ctcggcagct cgccgtgaag ttccaggtag acgaggctat
     3361 ccgggatatt tatatacaaa tttatcaact ctatacgaaa gggctggtcg cttagttggt
     3421 aaaaaaggtt cagtgacaca gattcctatt ttaacaatgc cagaagatga cataacacat
     3481 ccaattcctg atttaactgg atacattact gaagggcaaa ttattttgtc gcatgagttg
     3541 tataatcaag gttatcgtcc accaatcaat gttttacctt ctctctctcg attaaaagat
     3601 aagggatctg gagaaggtaa aactcgtgga gatcatgctc caactatgaa tcaactgttt
     3661 gcagcctatg cccaagggaa aaaggttgaa gagttagcag tagtattagg agaatcggct
     3721 ttatctgatg tagataaatt gtatgtgaag tttacaaagc gttttgaaga agagtacatc
     3781 aaccaaggat tttataaaaa tcgaaatatt gaagatacgt tgaatcttgg gtgggaatta
     3841 ctatcaattc ttcctagaac agagttaaaa cgtatcaaag atgatttgct tgataaatac
     3901 ttacctttgg tagaagttta atccagaaat ggagtgatta tctatggtgc gtttgaatgt
     3961 aaaaccaact cgtatggaat tgaataactt aaaggaacgt ttgaaaacag ctgaacgtgg
     4021 acataagtta ttaaaggata aaagagatga attgatgagg cgatttattt ctttgattcg
     4081 tgagaataat caacttcgga aagaagtaga aagttatcta attgataatc taaaagcctt
     4141 tgcagttgct aaatcattaa agaactctct aatggtggag gaattatttt caattccatc
     4201 gaaagaaatt gaattatttg ttgagaaaga aaatatcatg agtgtaacag ttcctagaat
     4261 gcatatgaat attacttctc aaaatgagaa cagtgaatac agctatttat cttctaatag
     4321 tgaaatggat gatgtatttg ctacaatgaa tagtttaatt gataaattac taagactggc
     4381 agaagttgaa aaaacgtgtc agttaatggc tgatgaaata gaaaaaacac gtagacgtgt
     4441 aaatggatta gaatattcga ttattccaaa cttgtcagaa actattcatt atatagaatt
     4501 gaaactagag gaggcagaaa gagccaattt agttcggatt atgaaagtga agtagatcct
     4561 ttatttagat tttaattaga tgaaccaata tcagcttgga taaggcggta agcctttcta
     4621 agctttttta ttgacagtat caggatatct ttttcaaaat tttggtttgt tagataatga
     4681 aaatgtttct accgatttag atttaggatt aataagtcgt aaatgtaatt ttaaagaaaa
     4741 agataagtta aaaaaagatg tattagcaag agttggtcta actcatattc atctagaaca
     4801 aaagatatat gaattgtctg gcggtgaagc ataacgtgtt gctttagcga aaatcattct
     4861 taaaaatcca ccattaatac tcgcggatga gctgactgca tcactcgatc cgacgacttc
     4921 acaaggaatt atgaaattat tattagatat gaaaaatgaa aatcgtctaa tcatcattgc
     4981 aactcataat cccgatattt ggaatcaagc agatgaagtt ataa
//
LOCUS       DAVMJI010000064         4532 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.066, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000064 DAVMJI010000000
VERSION     DAVMJI010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4532
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.066"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(<1..367)
                     /locus_tag="VYR58_001982"
     CDS             complement(<1..367)
                     /locus_tag="VYR58_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4297 domain-containing protein"
                     /protein_id="HEV3623071.1"
                     /translation="MIMIDNLKNHFDNLFTEDKNNILNIDFSQSIDKLYAPINNEDIE
                     DILLAEETSDDGGIIAMTGFYYQMMVAVLYLGEVFQGDWDGMFLDHHQDIVLFNNSKK
                     IIKFIQVKTKNSTYAPANKK"
     gene            complement(402..1169)
                     /locus_tag="VYR58_001983"
     CDS             complement(402..1169)
                     /locus_tag="VYR58_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV3623072.1"
                     /translation="MGIQDYTDSEFKQALERNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFARKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKSRGYEVQLALIATKPKLSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEKLAIFERIQIYQRDRSCVYDSKENTT
                     SAAEVLQECLFGKWSKVEEEMLKVGEEILETLCNRTE"
     gene            complement(1169..1645)
                     /locus_tag="VYR58_001984"
     CDS             complement(1169..1645)
                     /locus_tag="VYR58_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3623073.1"
                     /translation="MIGKNIKSLRKTHDLTQDDFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(1716..1988)
                     /locus_tag="VYR58_001985"
     CDS             complement(1716..1988)
                     /locus_tag="VYR58_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623074.1"
                     /translation="MFTKLFKKNQDNSDIFKKLIHRLSDMSVQDLEKIDRLLDIIFTP
                     DQGSEQLKTESTYREETLDDTLKEAKNQLHKEQLEKNLERFRKNSQ"
     gene            complement(2026..2409)
                     /locus_tag="VYR58_001986"
     CDS             complement(2026..2409)
                     /locus_tag="VYR58_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEV3623075.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFGNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            complement(2406..2639)
                     /locus_tag="VYR58_001987"
     CDS             complement(2406..2639)
                     /locus_tag="VYR58_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623076.1"
                     /translation="MTIIERLEEKVTRQENKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGRERQFDDSEFRKDEMSE"
     gene            complement(2690..3775)
                     /locus_tag="VYR58_001988"
     CDS             complement(2690..3775)
                     /locus_tag="VYR58_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEV3623077.1"
                     /translation="MEIEECKQISILDVASRLGISFKQVSSSIYELPEHDSFRIFSNT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKEALGFLSQEPFQKEAVQEKRERPFYYPLKRI
                     EDSNCSLARYYLTECRGISEEIIQKMIQQGLIAQASWKTNETVEPVIVFKSFNHRHKL
                     QAASLQGIYKNPALSRERLKTILKGSHGNVGISFDIGKPNRLVFCESFIDLMSYYELH
                     QQSLSDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVTPSKLLPLINTIRDTTT
                     YFNNHPDLLTLAVDCDDAGKDFSDKLSQEGFPVLLDLPNNEFGKEKIDWNDILREKKS
                     DLQLMIETAKETLRNQPVRQTSQCLEL"
     gene            complement(3785..4423)
                     /locus_tag="VYR58_001989"
     CDS             complement(3785..4423)
                     /locus_tag="VYR58_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV3623078.1"
                     /translation="MLNKVKTKALISVGAVATTSFILMMGYTVGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVQLSYSKLPGKLLVNQVQVWKSGLDDLDKATTKNLEESSIPSLPNTTTK"
BASE COUNT         1298 a          868 c          661 g         1705 t
ORIGIN      
        1 tttttttatt tgcaggtgca taggtgctat ttttagtttt cacttggata aattttatta
       61 ttttctttga attattaaac aaaacaatat cttggtgatg atctaaaaac atcccatccc
      121 aatcaccttg gaatacttct cccaaataaa gtacagccac catcatctga taataaaatc
      181 ctgtcatagc aataatccca ccatcatctg aggtctcctc tgctaaaaga atatcttcaa
      241 tatcctcatt atttattgga gcatatagtt tatcaataga ttgactaaaa tctatgttta
      301 gtatattgtt tttatcctca gtaaatagat tatcaaaatg attttttaaa ttgtctatca
      361 taatcagcta tatttcactt cctaatattt tttcttcatc attattctgt acgattacac
      421 aaggtttcta aaatctcttc tcccaccttc aacatctctt cctctacctt gctccatttt
      481 ccgaagaggc attcttgtag cacttctgct gctgaagttg tattttcttt tgaatcatat
      541 acacaacttc tatctcgttg gtaaatttga attctttcaa agatagctag tttttctaat
      601 tgtcgtgtat tatcaactag atgatttaca atgaaatcat gatgttcttt tggagttgca
      661 cgtgcttgat ttggattgat agcgtatagt tcttcgtatc ggataagggt gctcagatag
      721 gacagcttag gctttgtcgc aatcaaggct aattgtactt catatcccct acttttcaag
      781 agttgtgctg ttttctttgg aacatcaatc gttcgtaaag ttccctctat caaaagattg
      841 tatcccaaat gactcaattc tgttactaaa gattctacca ttttccttgc aaaatccttg
      901 gtgtattcaa cactatcttt gccatattct tgctgaagtt ctaaatagtg tggatgctga
      961 gaacgaaaac tatcgccatc tatgataaca atatttcctt gaaactcttt ctgtttaata
     1021 cgatgaattg tagtctttcc agcaccactt tgccctccaa gcaaaatcgc tataggttgc
     1081 ttactggact tttttcctct tgtcagagag cgaaggtttc gctctaaagc ctgtttgaat
     1141 tcactatcgg tataatcttg gattcccatt aggctaccat ccgtttttca gatatctcta
     1201 acatacgttc aattccatcc aaatagccgc tatacctctc tatttcatca aaagtttcta
     1261 ctaaatagat attcgtatga atcaagtcag atagatcatc actcattaaa atccaaggat
     1321 tagattcatc atcaatgcta attccctgac tatcttgata acgatagagt cgagatagta
     1381 gattagcacc tctttctttc acaatttcaa tttttaaagt caattcataa tcttcaacag
     1441 gattaagcat tttatcttct cctacaatat cgacataaga tacattaaac ttctgacaaa
     1501 tgatgtctat tagttccgta gagactgaac tcgttccatt ttcataccgg ctcaagctat
     1561 ttcgagaaat tcctacaatt cgggcaaagt cgtcttgtgt taagtcatgt gttttacgta
     1621 aggattttat gttctttcca atcatggcaa actcctttta tttttatacc accattataa
     1681 catttagaaa aagtaaatgc accatttttg gtgcattatt ggctattttt cctaaatctc
     1741 tctaaattct tttccaattg ttccttatga agttgattct ttgcttcctt taatgtgtcg
     1801 tccaaagttt cttctctata agttgattct gtttttagtt gttctgatcc ttgatctgga
     1861 gtgaaaatga tatctagcag tcggtctatt ttttcaagat cttgaacgga catatcagat
     1921 agtcgatgaa ttagcttctt aaatatatca ctattgtctt gattcttctt aaaaagtttt
     1981 gtaaacatct atagcctctc aaaaaaagca gcctcttagg actgcttaat gtaattctga
     2041 aatcgcatca taaattgact gcaatttctt attatcttta ttctttgtgt caattaacgt
     2101 atgtagctct tcaattttct tctgactgct ttgaatatcg ctattgttat ccgcaatcag
     2161 tcttttaaga tgttgctgat aacttgtagt gatatctgtt tcttttcctg ttctaacctc
     2221 tgtaactttg ggtttagaac tagaatttga ttctgtcaca ggtgcttgtt ttctcttttg
     2281 aaaagctgct tcataattta catcattacc tccttgatga tttccaaata aggccgcaat
     2341 tttatctgga tcttcttgat tttctgattt actttctaat ggttgattaa aattccaatc
     2401 ttttgtcatt cactcatttc atcctttcta aattcagaat catcgaattg tctttctcta
     2461 ccgaaggcat ggtcaagagc ttcttcaaaa ctcatgtgac taatgctttg acgccttttg
     2521 aacgtcgcaa acatcgctgt ctccagttgc tctttgtaag cagcaagttt ttctgtctct
     2581 cttgctacct tgttttcttg cctagtgacc ttttcttcta ggcgttcaat aatggtcata
     2641 tacgaacctc cttcatttta atattagcta aaacatcttg attttgttat cacaattcta
     2701 aacattgaga ggtttgtctt actggttgat tcctcaatgt ctcttttgca gtctcgatca
     2761 tcaattgtaa atctgatttc ttttctcgaa gaatatcgtt ccagtctatt ttttctttcc
     2821 caaattcatt attaggtaaa tccagtaaaa caggaaatcc ttcttgagat aacttatcag
     2881 aaaaatcttt tcctgcatca tcacaatcta ccgcaagtgt caataaatca ggatgattat
     2941 tgaaataggt agtggtatca cgaattgtat tgatcaaagg caataacttt gaaggtgtta
     3001 ctgtatctaa gaattccaac ttctgatttt cttcagctat cagtcgtaaa gtttgataag
     3061 caacaacaga cctttttaat ccctccatag ataccaagcg aacatctgat agactttgtt
     3121 gatgaagttc gtaatagctc atcaagtcga taaacgattc acaaaagacc aatctatttg
     3181 gtttaccaat gtcaaaggat attccaacat ttccatggct tccttttaga atcgttttta
     3241 acctctctct agaaagagcg ggattcttat aaatcccttg taagcttgct gcctgcagct
     3301 tgtgacgatg attaaagctt ttaaaaacga taacaggttc aactgtttca tttgttttcc
     3361 agctggcttg tgctattaaa ccttgttgaa tcatcttttg tatgatttct tctgagattc
     3421 ctctacattc tgttaagtaa tatctggcca gactacagtt tgaatcttct attctcttta
     3481 aaggataata aaatggtctc tctctctttt cttgaacagc ttctttttga aaaggttctt
     3541 gagaaagaaa acctaaagct tctttaaaag agattccctt aacaagtcga acaaaatcaa
     3601 tgacatcacc ttgaatatct cttgaaaacc atttaaaagt attggtattc gaaaaaatcc
     3661 gaaatgaatc gtgttcagga agctcatata tactgctaga aacttgttta aaggagatac
     3721 ctaaacgact tgctacatca agaattgaaa tttgcttaca ttcttctatt tccatgcaat
     3781 atcatcattt tgtcgtagta tttggcagtg atggtattga tgattcctct aaatttttag
     3841 tagttgcctt atctaaatca tctaacccag atttccaaac ctgcacttgg ttgaccaata
     3901 acttaccagg aagtttagaa taagataatt gaactgttct ggtttctgtc tgattggtct
     3961 ttgattggtt ggcattcttt aaatcagata cataggttac attataagac accatggcaa
     4021 tggcttgatt cgtagtctga ttgacaaaaa tatcagcttt ttcaaaatga taatccaaaa
     4081 tatagtcctt ataaacttgg ttcatagcat cattttgact tgtcaattct tgagaataag
     4141 cagattcagt catatagggc tgaatgcgtg tattattttc tccaagcttt tctttcgtat
     4201 aatactgtgt caaaaattct tttacagtat ctgatgacaa aatgcttgct ttatcttctg
     4261 cttgtttgtc ctctacaagt ttagctgcag ccaattcgat ttctttgcga ctttgtttag
     4321 cagtagaatg ttgcccaaca gtatatccca tcatgagaat aaagcttgtt gtggctactg
     4381 ctccaacact aattaaggct ttagttttga ctttatttaa catcttagac cttctttcta
     4441 taaaaactag gtcaagaata acaaaaagaa cttgtaagtt ttatcacata atgagttaaa
     4501 catatctatt aaaattttaa cacctgtatc ct
//
LOCUS       DAVMJI010000065         4477 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.067, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000065 DAVMJI010000000
VERSION     DAVMJI010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4477
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.067"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            343..>4477
                     /locus_tag="VYR58_001990"
     CDS             343..>4477
                     /locus_tag="VYR58_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV3623079.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARVKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     "
BASE COUNT         1725 a          652 c          870 g         1230 t
ORIGIN      
        1 acaacctcaa aacagtgttt tgagctgact acgtcagttc catctacaac ctcaaaacag
       61 tgttttgagc aacctgcggc tagtttccta gtttgctctt tgattttcat tgagtactaa
      121 tcttactttt taacgtgtgc taaaaaataa attaatgcat gttaattttt cttgaattaa
      181 atttttttaa atgatatact gtttttatag agagataaca attatatata aatgtactac
      241 tctatttcct agataatact tagtaaaact ttttataaca aaggctagca aagttaaagt
      301 ttattatcta ttggaagtta aataaatatg taaggaatta aaatgaaaaa aagtacagta
      361 ttgtcattaa ccacagctgc agttatttta gcagcctatg cccctaatga ggtagtctta
      421 gcagacacat ctagctctga agatgcttta aacatctctg ataaagaaaa agtagtatta
      481 gataaggaaa cagaaaataa agagaaacat gaagatattc ataatgctat agaaacttca
      541 caggatttta aagagaagaa aacagcagtc attgagggaa aagaagttgt tagtaaaaat
      601 cctgtgacag acaataacac tagcaatgaa gaagcaagag tcaaagaaga ttccaatcaa
      661 tcccaaggag atcatacgga ctcatttgtg aataaaaaca cagaaaatcc caaaaaagaa
      721 gataaagttg tctatattgc tgaatttaaa gataaagaat ctggagaaaa agcaatcaag
      781 caactatcca atcttaagaa tacaaaagtt ttatatactt atgatagaat ttttaacggt
      841 agtgccatag aaacaactcc agataacttg gacaaaatta aacaaataga aggtatttca
      901 tcggttgaaa gggcacaaaa agtccaaccc atgatgaatc atgccagaaa ggaaattgga
      961 gttgaggaag ctattgatta cctaaagtct atcaatgctc cgtttgggaa aaattttgat
     1021 ggtagaggta tggtcatttc aaatatcgat actggaacag attatagaca taaggctatg
     1081 agaatcgatg atgatgccaa agcctcaatg agatttaaaa aagaagactt aaaaggaact
     1141 gataaaaatt attggttgag tgataaaatc cctcatgcgt tcaattatta taatggtggc
     1201 aaaatcactg tagaaaaata tgatgatgga agggattatt ttgacccaca tgggatgcat
     1261 attgcaggga ttcttgctgg aaatgatact gaacaagata tcaaaaactt taacggcata
     1321 gatggaattg cacctaatgc acaaattttc tcttacaaaa tgtattctga cgcaggatct
     1381 gggtttgcgg gtgatgaaac aatgtttcat gctattgaag attctatcaa acacaacgtt
     1441 gatgttgttt cggtatcatc tggttttaca ggaacaggtc ttgtaggtga gaaatattgg
     1501 caagctattc gggcattaag aaaagcaggc attccaatgg ttgtcgctac gggtaactat
     1561 gcgacttctg cttcaagttc ttcatgggat ttagtagcaa ataatcatct gaaaatgacc
     1621 gacactggaa atgtaacacg aactgcagca catgaagatg cgatagcggt cgcttctgct
     1681 aaaaatcaaa cagttgagtt tgataaagtt aacataggtg gagaaagttt taaatacaga
     1741 aatatagggg cctttttcga taagaataaa atcacaacaa atgaagatgg aacaaaagct
     1801 cctagtaaat taaaatttgt atatataggc aaggggcaag accaagattt gataggtttg
     1861 gatcttaggg gcaaaattgc agtaatggat agaatttata caaaggattt aaaaaatgct
     1921 tttaaaaaag ctatggataa gggtgcacgc gccattatgg ttgtaaatac tgtaaattac
     1981 tacaatagag ataattggac agagcttcca gctatgggat atgaagcgga tgaaggtact
     2041 aaaagtcaag tgttttcaat ttcaggagat gatggtgtaa agctatggaa catgattaat
     2101 cctgataaaa aaactgaagt caaaagaaat aataaagaag attttaaaga taaattggag
     2161 caatactatc caattgatat ggaaagtttt aattccaaca aaccgaatgt aggtgacgaa
     2221 aaagagattg actttaagtt tgcacctgac acagacaaag aactctataa agaagatatc
     2281 atcgttccag caggatctac atcttggggg ccaagaatag atttactttt aaaacccgat
     2341 gtttcagcac ctggtaaaaa tattaaatcc acgcttaatg ttattaatgg caaatcaact
     2401 tatggctata tgtcaggaac tagtatggcg actccaatcg tggcagcttc tactgttttg
     2461 attagaccga aattaaagga aatgcttgaa agacctgtat tgaaaaatct taagggagat
     2521 gacaaaatag atcttacaag tcttacaaaa attgctctac aaaatactgc gcgacctatg
     2581 atggatgcaa cttcttggaa agaaaaaagt caatactttg catcacctag acaacaggga
     2641 gcaggcctaa ttaatgtggc caatgctttg agaaatgaag ttgtagcaac tttcaaaaac
     2701 acggattcta aaggtttggt aaactcatat ggttccattt ctcttaaaga aataaaaggt
     2761 gataaaaaat actttacaat caagcttcac aatacatcaa acagaccttt gacttttaaa
     2821 gtttcagcat cagcgataac tacagattct ttaactgaca gattaaaact tgatgaaaca
     2881 tataaagatg aaaaatctcc agatggtaag caaattgttc cagaaattca cccagaaaaa
     2941 gtcaaaggag caaatatcac atttgagcat gatactttca ctataggcgc aaattctagc
     3001 tttgatttga atgcggttat aaatgttgga gaggccaaaa acaaaaataa atttgtagaa
     3061 tcatttattc attttgagtc agtggaagaa atggaagctc taaactccaa cgggaagaaa
     3121 ataaacttcc aaccttcttt gtcgatgcct ctaatgggat ttgctgggaa ttggaaccac
     3181 gaaccaatcc ttgataaatg ggcttgggaa gaagggtcaa gatcaaaaac actgggaggt
     3241 tatgatgatg atggtaaacc gaaaattcca ggaaccttaa ataagggaat tggtggagaa
     3301 catggtatag ataaatttaa tccagcagga gttatacaaa atagaaaaga taaaaataca
     3361 acatccctgg atcaaaatcc agaattattt gctttcaata accaagggat caacgctcca
     3421 tcatcaagtg gttctaagat tgctaacatt tatcctttag attcaaatgg aaatcctcaa
     3481 gatgctcaac ttgaaagagg attaacacct tctccacttg tattaagaag tgcagaagaa
     3541 ggattgattt caatagtaaa tacaaataaa gagggagaaa atcaaagaga cttaaaagtc
     3601 atttcgagag aacactttat tagaggaatt ttaaattcta aaagcaatga tgcaaaggga
     3661 atcaaatcat ctaaactaaa agtttggggt gacttgaagt gggatggact catctataat
     3721 cctagaggta gagaagaaaa tgcaccagaa agtaaggata atcaagatcc tgctactaag
     3781 ataagaggtc aatttgaacc gattgcagaa ggtcaatatt tctataaatt taaatataga
     3841 ttaactaaag attacccatg gcaggtttcc tatattcctg taaaaattga taacaccgcc
     3901 cctaagattg tttcggttga tttttcaaat cctgaaaaaa ttaagttgat tacaaaggat
     3961 acttatcata aggtaaaaga tcagtataag aatgaaacgc tattcgcgag agatcaaaaa
     4021 gaacatcctg aaaaatttga cgagattgcg aacgaagttt ggtatgctgg cgccgctctt
     4081 gttaatgaag atggagaggt tgaaaaaaat cttgaagtaa cttacgcagg tgagggtcaa
     4141 ggaagaaata gaaaacttga taaagacgga aataccattt atgaaattaa aggtgcggga
     4201 gatttaaggg gaaaaatcat tgaagtcatt gcattagatg gttctagcaa tttcacaaag
     4261 attcatagaa ttaaatttgc taatcaggct gatgaaaagg ggatgatttc ctattatcta
     4321 gtagatcctg atcaagattc atctaaatat caaaagcttg gcgagattgc agaatctaaa
     4381 tttaaaaatt taggaaatgg aaaagagggt agtctaaaaa aagatacaac tggggtagaa
     4441 catcatcatc aagaaaatga agagtctatt aaagaaa
//
LOCUS       DAVMJI010000066         4290 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.068, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000066 DAVMJI010000000
VERSION     DAVMJI010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4290
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.068"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..674
                     /locus_tag="VYR58_001991"
     CDS             <1..674
                     /locus_tag="VYR58_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV3623080.1"
                     /translation="KRIKRLRRISGGDTYTIIYLKLLLLSLKDEGKLYYDGVESDFIK
                     ELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTEIPNLIGSETAWAEKKRRYR
                     QNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYK
                     NLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYD
                     VGESL"
     gene            1358..1519
                     /locus_tag="VYR58_001992"
     CDS             1358..1519
                     /locus_tag="VYR58_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623081.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1611..3290
                     /locus_tag="VYR58_001993"
     CDS             1611..3290
                     /locus_tag="VYR58_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV3623082.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRSQKAMEGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTYLLSGIVKCPICGVGMFGNKCTKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3558..4124
                     /locus_tag="VYR58_001994"
     CDS             3558..4124
                     /locus_tag="VYR58_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623083.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
BASE COUNT         1688 a          543 c          889 g         1170 t
ORIGIN      
        1 acaaaaggat aaaaaggtta aggagaatat ctggaggaga tacctatacg ataatctacc
       61 taaaacttct actactaagc ctaaaagatg agggcaaact ctattatgac ggagtagaaa
      121 gtgattttat aaaagagtta gcactaacca tagatgaaac agacgatgat gtaatggtaa
      181 cagtaaatta tttaatcaat caaggcttat tagaagttgt aacagaaaat gatgaatact
      241 acctaactga aataccaaac ttaatcggat cagaaacagc ctgggcagag aaaaaaagaa
      301 gatacagaca aaataaacag aggacattgt ccttaatgag tccaacccat gtccgacaag
      361 agatagagat agagaaagat atagagatag ataaagagag agagggagag atagataaaa
      421 agtccacccc cattttttat ggagaattca aaaatgtaag gttaagtaaa gaagaatata
      481 aaaatctaaa agaaaaatta aactcacaca cagatataat gataaataaa ctatccagat
      541 acatggaaag cagtggtaag acctatcaaa accactatgt gacaatctta aaatggtatg
      601 aagaagataa agacaaacta agacagaaag gtttaaataa aaaaatgaat tatgatgtag
      661 gagaatcttt atagataaaa agaggtggaa aggcactatt aaagacttta agtctaaaaa
      721 ggtatcaaag tatgccagag ataaaaaaat ataaatatga cactttaaag gcgattagaa
      781 aattaaagaa atgctagaag acttttagat gacagttacc aagagggtct aattttcact
      841 gctacttatg cagtgaaaat tagacctttt tatataagca aattctattt caaaattggt
      901 taccaagaaa gacttctttt cactgttaag tataagaggg taatttatag aattttgtta
      961 cattaagata aatattttct gatggtcaaa ttttaaaaag attaataact ctcgataaat
     1021 tttgaacctt aacaattgaa tagaccaaga caagatgtta attatttttg gagcgtaata
     1081 acctatccgt caagatcttt cggctgaata attcggcaaa aaaagttctg ctaagtaaaa
     1141 agaaagtgag cgataagtaa gagtttgaat atagggaggg ataccctatc cgctatgaag
     1201 aaaatgagga taatgatact tctaaggttg aagccggctc atccggaata gaggcggagg
     1261 tgagattcct atgttgctaa tccaaagcac ttgtcaatgt caaaaaactt aattaaacaa
     1321 ataattatta gatataaaac tttagaggag gtatatattg gacaatgact ggaatggatt
     1381 ggctgattta atagcaaatc tgattgcaaa atatgctggt gctttagatt tagataatct
     1441 acccgatcca acgccagcaa aaaatcaaga gatgaaaaat agttttgaca tggcaaaaac
     1501 acaaattgag acggactaat aaaagtgtta taatatactt gaaatgatag tccaaactta
     1561 aattaaaaaa attatatatg atatagaaaa attatattga ggttaatact atgtcaaaag
     1621 aaaaaataaa agtatacctc tatacacgag tatctacgtc aatacagata gaggggtatt
     1681 cgttagaggc acaaaaatca cgaatgaaag cttttgctat ttacaacgat tatgaaattg
     1741 ttggagagta tgaagatgcc gggaagtctg gcaagtctat tgaaggtaga atacagttca
     1801 atcgaatgat ggaagatata aaatctggaa aagatggagt atcttttgtt cttgtgttta
     1861 agttatcaag atttgcaaga aatgccgctg atgttctttc tacacttcag ataatgcagg
     1921 attatggagt taatcttatc tgcgttgaag atggcattga ttcatctaaa gatgctggga
     1981 aactaatgat ttctgtttta tcagctgtgg ctgaaataga aagagaaaac atccgtattc
     2041 aaacaatgga aggtcgcagt caaaaagcaa tggaaggaaa atggaatggt ggctttgctc
     2101 cgtatggata taaacttgaa gacggcaagc tgtttataaa tgaggaagag gcagttgcaa
     2161 taagaacgat tttcgaccag tatgtaaata ctacgatagg agccaatggg atatctaaat
     2221 acttagagaa tcatggaatt agaaaaatcc caagacagaa tggtaagaat cctttgtttg
     2281 atgcaggtct tataagaaag atattaaaga atcctgtata taatgggaaa atagcatttg
     2341 gaagaagaac tttagaaaaa gttcatggta caagaaatga atataagcag gttgaacaag
     2401 atgaatatct aatatctgaa gggatacatg aagctatagt ttccgatgaa gtttggcaag
     2461 ctgctcaggt taagctaaaa tctcaagcaa agaaatatga gcatgtgaat aaaggaaaag
     2521 atacacgcac atacttgctt tctggaattg taaaatgccc gatatgtgga gtgggaatgt
     2581 ttgggaacaa gtgtaccaag aaaaagaaag atggcacaaa gtataaagat ttttattact
     2641 atggttgtaa acataggcag atgataagag gtcataagtg tacattcagt aagcaaatta
     2701 gagaagaatt gttagatgat gctgttgcag aggtgattgt caagatagta agtaatccga
     2761 aatttgcttc tatgatgcaa gaaaaaatca acatgaaggt ggatacctct gaaatagaaa
     2821 aagaaataga taattaccaa aaggaattga gaaagagtca ttctacaaag tttaagctaa
     2881 ttgaggaaat agataattta gatgttgaag ataagcacta taagagaagg aaacaggatt
     2941 tagatgatag actatatcgt atgtatgaca aaatagatga attagaatca tcactaattg
     3001 atgcgaaagc aaagaaacag actattgaag ctgaaaaact tacaggagat aacatatata
     3061 aggttctgat ctattttgat aagctctata aagtcatgaa tgatgtagag cgtaggcagt
     3121 taatttcagc tttgatttct gaaattcaag tttatgaaga aaaacaatct aacggacaat
     3181 ggctaaaatc cattactttt aagctaccaa ttatagaaga aaatctcaac atagatttgg
     3241 acaatgatga acaagttgaa tgtgtaagtt tattagagaa acgtagttaa tcctcaaaag
     3301 gttccccaaa ctttttgagt cccactgacg catcacgctg aggcggtatc actgcttgta
     3361 cgagttgaag catcagcgaa gtaaaagtag atgttcagcc aatgcgacga ggtgagaccg
     3421 aaggtcgata aggtgtgttc tgggtatagg actcgtaaag taagtaggaa atatgatgag
     3481 atgatacaga gagcctgaat tggtcaggtg acgtgcttat ttacattagc ctgataatga
     3541 aaatggagag attatcgatg gttatattgg aattgtacca aaatgattat tctaaagatt
     3601 tagtagcatt tgattccata gaagatggga aagcctttgt ggctcaaatc ccgggataca
     3661 ctctggaaac agaagatggt tttgaagtgg agtattttaa tcctaaaaac ataccggatt
     3721 atatggaaat tatttttaac ggaaatattg ttcctttatc taaatttatg ttcgatcctg
     3781 aggaaaatgt aaacattatt tggaaagaga tttcaaattt atccctcaaa aatgatagag
     3841 tgatcgaagg atattcaaaa attgatgcat atgtcgttaa caaccatgaa gttaaagcct
     3901 atgtcgaaac aagagaaacg aactatcgta aagcaaaaga cttcttagaa agccgcggat
     3961 atgaaatcga cagaagcttt ttcggaagtg aagacggtga agcgattctt tacagaaaaa
     4021 aagggatcga agtttggcat ttcttgtgtc acttagaccc aatgtttgta gagattgaag
     4081 atgtagaagg atatgttaaa gaagaagttg gagagattca atagtcaacc aaagttcctt
     4141 gtgagtatat acctttgcta gtaaaagagt caaaacgtta taacgaaggg gggaagaaaa
     4201 cccttgagtg taagtctttt tcttgtttag agggaaagta ttagagtagc cgctcataat
     4261 ttatactaga tttgataact gatttgagac
//
LOCUS       DAVMJI010000067         4238 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.069, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000067 DAVMJI010000000
VERSION     DAVMJI010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4238
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.069"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            98..864
                     /locus_tag="VYR58_001995"
                     /pseudo
     CDS             98..864
                     /locus_tag="VYR58_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850213.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1683..2042
                     /locus_tag="VYR58_001996"
     CDS             1683..2042
                     /locus_tag="VYR58_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623084.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            2052..2417
                     /locus_tag="VYR58_001997"
     CDS             2052..2417
                     /locus_tag="VYR58_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV3623085.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYEQLVFELRRIGNNINQIARAINQSHLISQNQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSY"
     gene            2404..>4238
                     /locus_tag="VYR58_001998"
     CDS             2404..>4238
                     /locus_tag="VYR58_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV3623086.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSHAEMVEMYNVNFSNNDKLYESRNDRQEKHQQTIHAHYLIQSFSPEDNLTPEEINR
                     IGYEIMMELTGGRFKFIVATHTDKDHVHNHILINAIDRNSDKKLIWNYALERNLRMIS
                     DRISKVTGAKIIEKRYSYRDYKKYRESSHKFELKQRLYFLLQQSKSFDDFLEKAKQLH
                     VQIDFSQKHSRFLMTDRTMIKPIRGRQLSKRDLYDEDFFKTYFAKQEIESRLKFLLKS
                     VYSLEELHVKAKELNLTIELKQKNVMFTLEEDGKKISLSHKKISDKKLYDVQFFNRYF
                     EDREVRDIQALENLQEDFQTFREEQHKEKVSAEEIEEAFKKYKEKRDAIHEFEIELTD
                     NQIEKLVDDGVYIQVSFGIKQSGLIFIPNYQLDIFEEDNHKKYKVYIRETSSYFVYNK
                     ENMDNNCFIKGRTLIRQLSNDSQKLPYRRPTLKSLKEKISEINLMIELSNTNKQYQEI
                     KDELVLEIAEIDMQLEETQEKIATLNKMAEVLINLKSEDHETRKLAKYDFDQMNMTES
                     IMLDRLNTDILKLQQELGNEINKYEEIARRLDLFVKIINTNKFTVL"
BASE COUNT         1547 a          631 c          835 g         1225 t
ORIGIN      
        1 agaggcaatc ataaaaaatg gaatagaaat agttgtagta actgatcata atactaccaa
       61 aggtattaaa aagttacaaa tggcagtctc aatcataatg aaaaattatc cgatttatga
      121 tatacatcct catattttac atggagtaga aattagtgca gcagataaat tgcatattgt
      181 atgtatatat gattatgaac aagaatcatg ggttaatcaa tggttaagtg aaaatattat
      241 aagtgagaaa gatggaagtt atcaacattc actgactata atgaaggatt tcaataatca
      301 aaaaatagtt aactatattg ctcatttcaa tagttatgac attttgaaaa aaggttctca
      361 cttatcaggt gcatataaac gaaaaatttt ttctaaagaa aatacacgat tttggagttt
      421 aatattaact cgaaagaatc ttcgcaacaa cttgatattc tctataaaga agttggtgta
      481 ttaagtttgg gacaaaaagt tgtagccatg cttgattttt tattagcata tagtgattat
      541 tctaaagact tcagaccatt gattattgat cagcctgaag acaatctaga caatcgttat
      601 atttgcaggc atttagttca gcagtttaga gatgtgaaag ctcaacgtca aattatttta
      661 gcaacacata atgctacaat tgtaacaaat tctatgacag atcaagttgt tattatggag
      721 tcagatggag ttaacggatg gattgaatca cagggatatg ttagtgaaaa atatataaaa
      781 aatcatatca tcaatcaatt agagggagga aaagattcct tcaagcataa aatgtctata
      841 tatgagacgg ctttatcaga gtagagtcag aaaaagtagg ttagaaattt agcctacttt
      901 tttctttgtc cgacaggcat agtgtgcatc tgaggtccaa gtcctctgtg gatatttgct
      961 gcagatgaaa ccaatagcga ctcctaagcc tgaatatcgt gaggtagggg ggataggaag
     1021 gaattagcga aatcaaggtt ctacaaacag aatcgtgact tgaagccata tatagcggat
     1081 gaggaactct aaaatccaaa taggtgtcgt aacctatata cgtaaattac gagagtaaac
     1141 taggaaagat gtacggctta ttccgtgagc gtttaggacg tagtacaacg aatcatggga
     1201 gtcagctgaa cacatagtat tgaagaaatt tctgtaatgg aaatggagcg aagaagtgaa
     1261 caattaaatg aatacctctc taattaaatt tgtcaattct aattcctggt atgaaaagac
     1321 agtgacctga aaatgtaaac gatgggagct gattataaat ataggacggt acatgcagtg
     1381 gtgttagaga ttagtcccta cttgatttgt gataacttcc ccaaatttct tctgctatac
     1441 ttttctcaac ttttaaaaat ccaactaaga attttacctg ggggtttggg ggcgaagcca
     1501 ccaagttatc ttatcgttgg ctgtcaaaac tggaaggttt tggttagctg gcgatatgat
     1561 tttttgggta ttgtaaccac aatgcttgag ctcgcaaaga ccgaacaagg actttaagaa
     1621 atttcccgta tgacacacgg ggtcggggtt tacccgagaa aggatgaaag tgaggaaaag
     1681 agatgtctga acagtaccgt gacattcgaa aagaggtaaa tctaaccgca gatgagctaa
     1741 aacagattga aaaaatgatg gaggttgata attatcgtca cttttcacca ttcgtcaggg
     1801 ataaaatttt gatgactgat gacaaacagt tagctgccaa agaatggttt tccctttggc
     1861 agtctcaaaa gtttgaacag atcagtcgag atgtgcattt ggttttgatt atcgcaagag
     1921 agaatcacca agtgactcaa gaacacgtgt caatcttatt gacctgcgtt caagaattga
     1981 ttgcggaagt caatcaagta cagtcactca gtcgtgggtt tcgtgaaaaa tacatgagat
     2041 aggaggctac tatggtttat cgttatcgta ccaatctcaa aaaagtattt ctaacagatt
     2101 cagaattaca ccaattgaat gaacggattg ctaagagcaa ttgtcaaaat ttctcagtct
     2161 atgccagaaa agttttgctt aatcccaata tgtcatttgt cacgattaac actgatactt
     2221 atgaacagtt agtgtttgaa ttgaggagga ttggaaataa catcaatcaa attgcgcgtg
     2281 cgattaatca aagccatctg atttctcaga accaattaca agaattgagt aaaggagtcg
     2341 gagagttaat taaggaagtg gacaaagaat ttcaagtgga ggtgaaaaga ctgaaggagt
     2401 ttcatggtag ttactaaaca ctttgcgacg cacggaaaaa aatatcgtag gcgtttaatt
     2461 aagtatattc tcaaccctga taaaacggac aatttgaaat tggtatctga ttttggcatg
     2521 agcaattact tggacttccc tagtcatgca gaaatggtag agatgtacaa tgtcaacttc
     2581 agcaataatg acaagttgta cgaatccaga aacgaccgac aagaaaaaca ccaacaaact
     2641 attcatgctc attacctcat tcaatcattt tctcctgaag ataatctgac acctgaagaa
     2701 attaaccgca ttggttatga gatcatgatg gaattgacag gaggtcgttt taagtttatc
     2761 gtagcaactc acacagacaa agatcatgtt cataatcaca tcctaatcaa cgctattgac
     2821 cgcaattcag ataaaaagtt gatatggaac tatgccttgg aacgaaacct ccgtatgatt
     2881 tcagaccgta tttctaaagt gactggtgca aaaattattg agaaacgtta ttcctatcga
     2941 gattataaaa aatataggga atctagtcat aagtttgaat tgaaacaacg tctttatttt
     3001 ttgctacagc aatctaaatc gtttgatgat tttttagaga aagcaaagca gttgcatgtt
     3061 cagattgatt ttagtcaaaa gcatagccgt tttttgatga cagatagaac gatgataaaa
     3121 ccaattcgag gacgccaact cagcaaacga gatttatatg atgaagactt ttttaaaaca
     3181 tattttgcca aacaagagat tgaaagtcgt ttaaaatttt tactaaagtc tgtttattca
     3241 ttagaagaat tgcatgtaaa ggctaaagag ttgaatctaa ccatcgagtt aaaacagaaa
     3301 aatgtgatgt ttaccctaga agaagatggc aaaaagataa gcctgagtca taaaaaaatt
     3361 agcgataaga aattgtacga tgttcaattt tttaatcgtt attttgaaga tagagaagtt
     3421 agagatattc aagcattaga aaatcttcag gaagattttc agacttttcg agaggagcag
     3481 cataaggaga aagtctccgc tgaagaaatc gaggaagcct tcaagaaata caaggaaaaa
     3541 cgagatgcta tccatgagtt tgagattgaa cttacggata atcagataga gaagttggtt
     3601 gatgatggtg tctatataca ggtttcgttt ggtatcaaac agagtggact catctttatt
     3661 cctaactacc agctagatat ttttgaggaa gacaatcata aaaaatataa agtctacatt
     3721 cgagaaacgt cttcttactt tgtctataat aaagaaaaca tggataataa ttgtttcatc
     3781 aagggtagga ccttaatcag acaattgagc aacgatagcc aaaaactccc ctatagacga
     3841 ccaactttaa aaagtcttaa agagaagatt tctgaaatta atcttatgat tgaactatct
     3901 aacacgaaca aacaatacca agaaatcaaa gatgagcttg tattagaaat tgcagagatt
     3961 gatatgcagc tagaagaaac ccaagaaaaa atcgccacct taaacaagat ggcggaagtc
     4021 cttatcaatt tgaagagtga agatcatgag actagaaaat tagctaagta tgattttgac
     4081 caaatgaaca tgacggaatc aataatgtta gatcgactca atacggatat tttaaaatta
     4141 caacaggaac ttggtaatga aattaataaa tatgaggaga tagctagaag attggatttg
     4201 tttgtgaaaa ttattaatac caataaattt acagttct
//
LOCUS       DAVMJI010000068         4177 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.070, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000068 DAVMJI010000000
VERSION     DAVMJI010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.070"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            720..1712
                     /locus_tag="VYR58_001999"
     CDS             720..1712
                     /locus_tag="VYR58_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3623087.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VYR58_002000"
     CDS             1714..2532
                     /locus_tag="VYR58_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV3623088.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VYR58_002001"
     CDS             2534..3319
                     /locus_tag="VYR58_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3623089.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3358..3636
                     /locus_tag="VYR58_002002"
     CDS             3358..3636
                     /locus_tag="VYR58_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV3623090.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3621..3818
                     /locus_tag="VYR58_002003"
     CDS             3621..3818
                     /locus_tag="VYR58_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV3623091.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1165 a          719 c          902 g         1391 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat tgatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cgatgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aatttcacaa tccataggca aactcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagcaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctgtc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tttccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ttggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccga aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagaa acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg
     3421 aaggatttgc cagaatggtt tggaatccca gaaagcacac aagcctatat agaaggaacc
     3481 acgacactgc aagtttggac cgcctatcag gagagtgatt tgactagatt tgtaagctta
     3541 tcctattcga gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag
     3601 gtagaaaaat tgggagccaa ttgcttgcta ctttagagag tgaagctcgt aaaaaagttg
     3661 gttatctgca ggtcaaaaca gtggcagaag gttctaataa agattatgat cgaacaaatg
     3721 acttttatcg aggtcttggc tttaaaaagt tagagatttt tcctcaacta tggaatccgc
     3781 aaaatccttg tcagattttg attaaaaagc ttgaataata ttacttgaca tctattctca
     3841 gagtgccata ctgtaagtgt aatcgccgat ttagctcagt tggtagagca aggcactcgt
     3901 aaagcctagg ttataggtag ataaacgact gaggagttga aaaaatagat aggtagaaga
     3961 taaccgttaa gccttattct tagcggttat ttatattgtt taatagcgct gatatttcat
     4021 caattatgcc tgttttcgtg tttccggtag ttgttcaagt ttattgctac tatttttgat
     4081 ggtatgaatg tgcttataat gtatcccggt taacgaaagt tttggactta tactcttaga
     4141 aaatctcttc aaaccacgtc aacgccgcct tgccgtg
//
LOCUS       DAVMJI010000069         4137 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.071, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000069 DAVMJI010000000
VERSION     DAVMJI010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4137
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.071"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..693
                     /gene="phtD"
                     /locus_tag="VYR58_002004"
     CDS             <1..693
                     /gene="phtD"
                     /locus_tag="VYR58_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV3623092.1"
                     /translation="MPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYT
                     LEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKP
                     EEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQ
                     VEHSVINAKIADAEALLEKVTDPSIRQNAMETLTGLKSSLLLGTKDNNTISAEVDSLL
                     ALLKKSQPAPIP"
     gene            903..4022
                     /gene="phtE"
                     /locus_tag="VYR58_002005"
     CDS             903..4022
                     /gene="phtE"
                     /locus_tag="VYR58_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV3623093.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSISKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNKKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1542 a          687 c          804 g         1104 t
ORIGIN      
        1 atgccttaca atcttcaata tactgtagaa gtcaaaaacg gtagtttaat catacctcat
       61 tatgaccatt accataacat caaatttgag tggtttgacg aaggccttta tgaggcacct
      121 aaggggtata ctcttgagga tcttttggcg actgtcaagt actatgtcga acatccaaac
      181 gaacgtccgc attcagataa tggttttggt aacgctagcg accatgttca aagaaacaaa
      241 aatggtcaag ctgataccaa tcaaacggaa aaaccaaacg aggagaaacc tcagacagaa
      301 aaacctgagg aagataagga acatgatgaa gtaagtgagc caactcaccc tgaatctgat
      361 gaaaaagaga atcacgctgg tttaaatcct tcagcagata atctttataa accaagcact
      421 gatacggaag agacagagga agaagctgaa gatactacag atgaggctga aattcctcaa
      481 gtagagcatt ctgttattaa cgctaagata gcagatgcgg aggccttgct agaaaaagta
      541 acagatccta gtattagaca aaatgctatg gagacattga ctggtctaaa aagtagtctt
      601 cttctcggaa cgaaagataa taacactatt tcagcagaag tagatagtct cttggctttg
      661 ttaaaaaaaa gtcaaccggc tccgataccg tagtaaaatg aatggagcat attttatgga
      721 gaagtaacct ttcgtgttac ttctcttttt tagaaaaacg taacagaaac ttgacaaaag
      781 taattttaaa tagtaaacta tttactggtt aattaaatgg ttaaataacc ggtttagaaa
      841 actatttaat aaagtaaaag aagttgagaa aaaacttcat catttattga aatgagggat
      901 ttatgaaatt tagtaaaaaa tatatagcag ctggatcagc tgttatcgta tccttgagtc
      961 tatgtgccta tgcactaaac cagcatcgtt cgcaggaaaa taaggacaat aatcgtgtct
     1021 cttatgtgga tggcagccag tcaagtcaga aaagtgaaaa cttgacacca gaccaggtta
     1081 gccagaaaga aggaattcag gctgagcaaa ttgtaatcaa aattacagat cagggctatg
     1141 taacgtcaca cggtgaccac tatcattact ataatgggaa agttccttat gatgccctct
     1201 ttagtgaaga actcttgatg aaggatccaa actatcaact taaagacgct gatattgtca
     1261 atgaagtcaa gggtggttat atcatcaagg tcgatggaaa atattatgtc tacctgaaag
     1321 atgcagctca tgctgataat gttcgaacta aagatgaaat caatcgtcaa aaacaagaac
     1381 atgtcaaaga taatgagaag gttaactcta atgttgctgt agcaaggtct cagggacgat
     1441 atacgacaaa tgatggttat gtctttaatc cagctgatat tatcgaagat acgggtaatg
     1501 cttatatcgt tcctcatgga ggtcactatc actacattcc caaaagcgat ttatctgcta
     1561 gtgaattagc agcagctaaa gcacatctgg ctggaaaaaa tatgcaaccg agtcagttaa
     1621 gctattcttc aacagctagt gacaataaca cgcaatctgt agcaaaagga tcaattagca
     1681 agccagcaaa taaatctgaa aatctccaga gtcttttgaa ggaactctat gattcaccta
     1741 gcgcccaacg ttacagtgaa tcagatggcc tggtctttga ccctgctaag attatcagtc
     1801 gtacaccaaa tggagttgcg attccgcatg gcgaccatta ccactttatt ccttacagca
     1861 agctttctgc cttagaagaa aagattgcca gaatggtgcc tatcagtgga actggttcta
     1921 cagtttctac aaatgcaaaa cctaatgaag tagtgtctag tctaggcagt ctttcaagca
     1981 atccttcttc tttaacgaca agtaaggagc tctcttcagc atctgatggt tatattttta
     2041 atccaaaaga tatcgttgaa gaaacggcta cagcttatat tgtaagacat ggtgatcatt
     2101 tccattacat tccaaaatca aatcaaattg ggcaaccgac tcttccaaac aatagtctag
     2161 caacaccttc tccatctctt ccaatcaatc caggaacttc acatgagaaa catgaagaag
     2221 atggatacgg atttgatgct aatcgtatta tcgctgaaga tgaatcaggt tttgtcatga
     2281 gtcacggaga ccacaatcat tatttcttca agaaggactt gacagaagag caaattaagg
     2341 ctgcgcaaaa acatttagag gaagttaaaa ctagtcataa tggattagat tctttgtcat
     2401 ctcatgaaca ggattatcca agtaatgcca aagaaatgaa agatttagat aaaaaaatcg
     2461 aagaaaaaat tgctggcatt atgaaacaat atggtgtcaa acgtgaaagt attgtcgtga
     2521 ataaagaaaa aaatgcgatt atttatccgc atggagatca ccatcatgca gatccgattg
     2581 atgaacataa accggttgga attggtcatt ctcacagtaa ctatgaactg tttaaacccg
     2641 aagaaggagt tgctaaaaaa gaagggaata aagtttatac tggagaagaa ttaacgaatg
     2701 ttgttaattt gttaaaaaat agtacgttta ataatcaaaa ctttactcta gccaatggtc
     2761 aaaaacgcgt ttcttttagt tttccgcctg aattggagaa aaaattaggt atcaatatgc
     2821 tagtaaaatt aataacacca gatggaaaag tattggagaa agtatctggt aaagtatttg
     2881 gagaaggagt agggaatatt gcaaactttg aattagatca accttattta ccaggacaaa
     2941 catttaagta tactatcgct tcaaaagatt atccagaagt aagttatgat ggtacattta
     3001 cagttccaac ctctttagct tacaaaatgg ccagtcaaac gattttctat cctttccatg
     3061 caggggatac ttatttaaga gtgaaccctc aatttgcagt gcctaaagga actgatgctt
     3121 tagtcagagt gtttgatgaa tttcatggaa atgcttattt agaaaataac tataaagttg
     3181 gtgaaatcaa attaccgatt ccgaaattaa accaaggaac aaccagaacg gccggaaata
     3241 aaattcctgt aaccttcatg gcaaatgctt atttggacaa tcaatcgact tatattgtgg
     3301 aagtacctat cttggaaaaa gaaaatcaaa ctgataaacc aagtattcta ccacaattta
     3361 aaaggaataa agcacaagaa aactcaaaac ttgatgaaaa ggtagaagaa ccaaagacta
     3421 gtgagaaggt agaaaaagaa aaactttctg aaactgggaa tagtactagt aattcaacgt
     3481 tagaagaagt tcctacagtg gatcctgtac aagaaaaagt agcaaaattt gctgaaagtt
     3541 atgggatgaa gctagaaaat gtcttgttta atatggacgg aacaattgaa ttatatttac
     3601 catcaggaga agtcattaaa aagaatatgg cagattttac aggagaagca cctcaaggaa
     3661 atggtgaaaa taaaccatct gaaaatggaa aagtatctac tggaacagtt gagaaccaac
     3721 caacagaaaa taaaccagca gattctttac cagaggcacc aaacaaaaaa cctgtaaaac
     3781 cagaaaactc aacggataat ggaatgttga atccagaagg gaatgtgggg agtgacccta
     3841 tgttagatcc agcattagag gaagctccag cagtagatcc tgtacaagaa aaattagaaa
     3901 aatttacagc tagttacgga ttaggcttag atagtgttat attcaatatg gatggaacga
     3961 ttgaattaag attgccaagt ggagaagtga taaaaaagaa tttatctgat ctcatagcgt
     4021 aaggaatagc agtagaaaaa gtctgaatca aaaatgaagt tctctcaaaa gttagaaata
     4081 aaactctgac tttgggagaa tttcatttta ttattaatat ataaaatttc ttgacat
//
LOCUS       DAVMJI010000070         3952 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.072, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000070 DAVMJI010000000
VERSION     DAVMJI010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.072"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            266..1669
                     /locus_tag="VYR58_002006"
     CDS             266..1669
                     /locus_tag="VYR58_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEV3623094.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            1858..2478
                     /locus_tag="VYR58_002007"
     CDS             1858..2478
                     /locus_tag="VYR58_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3623095.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYEELEKIDILNYKCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDN
                     DNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            2493..3233
                     /locus_tag="VYR58_002008"
     CDS             2493..3233
                     /locus_tag="VYR58_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3623096.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            3236..>3952
                     /locus_tag="VYR58_002009"
     CDS             3236..>3952
                     /locus_tag="VYR58_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV3623097.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQ"
BASE COUNT         1389 a          498 c          764 g         1301 t
ORIGIN      
        1 gattctctgg agttatggat ctcgttccaa tatgtgcacg ttggaatgtc agtgcttata
       61 tggggggaat ccaaaggatt ctcccttttt attttaataa gtctgtctag ctatagatat
      121 attaagtttg atagaatttc ttggagattt tgttatggat tataatttca atttggagca
      181 tcctttcttt ttcactaata atgattatag tacagatact agcataaagt actaagtaag
      241 tctgcctttt aattggcacg aagtaatgaa taatgatgag tgggtttatc aataccctat
      301 tggaaaattt gttgaaagac aagggtggaa aatacacatt agttcagagt ataatagttc
      361 acacgaattg ttacaagatg tagcaaaaat ttgccatgaa atgcgaattc catttaaaca
      421 tcttagtaca gaagacaaat ttatcatgcg aaacgggaaa ttggttagtc gaggattttc
      481 tggtaaattt attacatgtt atccaaatca aaatgaatta gagtcggttt tgcaaaggtt
      541 agaaagtgcc ttaaagcaat ataatgggcc atatatttta agcgataaac gttgggatga
      601 agcaccaata tatctgaggt atggtgtgtt taggccgtca agggatgatg aaaagaaggt
      661 tgttattgat gaattaattg ttggcgatga agttgttaaa gatgaacgtt taccagtatt
      721 taaaattcca aaaggtatag tgccccctga ctttttgaat aaatggcttg acaagaaaga
      781 taaaaaacag ggagactttc cctttattat agataatgca attagatttt caaacagtgg
      841 tgggatatat aatgctagac taaaagaaga tgggaaaaaa ataattttaa aagaggctag
      901 accgtataca ggtctaggat ttgatggtac ttattcttca gagagattag cttcggagtg
      961 caaagcacta aaaattctaa atgaatggag tgagatgcct aaaatatact ggtacggtaa
     1021 gatctgggag cacaccttct taggaattga acatatgaag ggcgttccac taaatagatg
     1081 ggttaccaat aattttcctt tatatgaagt tgttgataag accaaagatt atctattgag
     1141 agtttcaaag atagtagaaa aactcatcga tttaacgaat aagtttcatt ctgaaaatgt
     1201 atatcatcaa gatttacatt taggaaatat cttggttaag gatgaagatg agattagtat
     1261 aatagactgg gaacaggctg tcttttcgaa tgatgaaaaa gttgtacata aagttgcagc
     1321 ccctggtttt agagcatggc gagaaacact tcccagtgag atagattggt atggtattag
     1381 acaaatagct cattatttat acatgccact agtaactaca tcggatttga catacaacta
     1441 tgtaagtcaa accaggatag aaggaaaaaa actatttgag tctttgggtt atacaagaga
     1501 acatatagat tatgtagaaa gtttattgtc atatctagat tctaaatgtc cacagattga
     1561 gaatatttcc aggaaaaaag ttttaaaacc catgcatgag attagaacta tcgagagtga
     1621 gcaagatata caagatttta ttataaaagc ttttctttta gtgaactgat aggtattttc
     1681 ttagcaaacg ataaagtttt agggccgata caatcaattg cctattcatt aaataagata
     1741 aatacaacca aagatttaag gaaaccgttt ttaaaatact taagtggaga gaagaatttt
     1801 gtagacgctg aacatgataa taacggactg tatacttcat caatagatga gatacacatg
     1861 aaagatgttg tatattctat tacaccagaa aataaattaa gtattgactt ctcatttaag
     1921 tcaccattta gggtattatt aacaggaact tctggcagtg ggaaaacaac gattttaaat
     1981 ttaattaatg gttctttaaa gccacaaaaa ggttatgtaa atttgttatc acatgggaaa
     2041 aagagttcag attcaatacc aacagttgat cagacaccat atatttttga cactactatt
     2101 cgtgagaacg taactttatt tcaaaatgaa tatttttcag atgatcagat aattgaggtg
     2161 ttaaaaaagg taaatctata tgaagaatta gaaaagatag atatactaaa ttataaatgt
     2221 ggtgaaaatg gtagtaattt gtctggaggt caaaaacaaa aaatagcttt agctagagct
     2281 ctgattagaa ataataaagt gtacttattt gacgaaatat cagctaattt agataatgat
     2341 aattcaaatt ccatacatga tattctgttc aatttaggta tttcatttat tgaagtttca
     2401 catcattatg acttaaatga caagagatac actgatatat ataaattgga aaatggaaca
     2461 cttttcaaaa ttaagtgatt ggaggcaaga atatggataa agattatata ttaaaagtga
     2521 aagggctgta tcatcaattt ttactaggaa ataataaaac gttgcaagtg ctgaaaaatg
     2581 tttctctttc tgcttcgaga ggagaattta taagtattct aggaattagt ggttctggaa
     2641 agtcaacttt attaaaatgt atttctagtt tgcttgaacc aacaagtggg gaagtaattt
     2701 taaatggaat caacccctat aaaatcagaa atgcaaaatt gtcaagtata agacgtaacg
     2761 aagtatcttt tatatttcaa gcatacaatt taataccttc cctgccggta atagaaaata
     2821 tagcacttcc tttgcgatta tcacaaaaaa aattaactat taaaaatgta gaaaacttac
     2881 tcaaaagaat gaagtttaat gctggcttaa acgattttgt tggaactctg tctggtggag
     2941 aacaacagaa ggttgctata gctagagcgg ttattgctga tagtgatata atatttgctg
     3001 atgagccaac tggggcttta gacagcgttt ctcgtgaagt aatttttgaa ttattgagag
     3061 agttagtagg ggcgggtaag tgtgtaatta tggtaacgca cgatatagaa ttggcctcga
     3121 aaactgatcg tgcattaata ttgaaagatg gaaaaatttt caaagaactt catagaccta
     3181 gcggggaaga gttgtataaa atcttagagg tacaatcaac tacggaggaa tagagatgct
     3241 cagattagtt tactatcaat ttttacataa taagaaacaa tggttaggcg tttcaccagt
     3301 aatttttgtt tcgagtttag ttatgggatt ggctgttaat ggggtaatta atgttgagaa
     3361 taattcgcaa gtatttgtcg gacttccaga tcctaaacca atttttatgt ttccgatagt
     3421 attcggagga gtaacattat tctttgtgct ctctaacata ataaatatgt tggttgaaat
     3481 ttttagagat gattacgaac ttctggaggt gttgggagca agtcgccttc aactatcatt
     3541 tcttgtgggg ggacagattt ttatcatttc ctcgattatt agttttattg catatctatg
     3601 ctctatattt gttacgtcaa attattatta ttttttacaa tactttttcg gggaaaatat
     3661 attacctgat atccaatttc aaacgagtgc tgttggatgt atcattacag tagtgttgat
     3721 ttcattttta gcctttctaa gtggttgctt ttatacgttc aagaagatta gaaataggaa
     3781 gagttctaaa ataaggcatg ttctttcaat agtaaaaaga atactgctat tggctggttt
     3841 tagtgttatc tggttgcttt ctttgcaaca aattttccaa gatagcacaa ttttagcgaa
     3901 ggcccagata atattcaata ttgtaatctt agatattgtg attatttatc aa
//
LOCUS       DAVMJI010000071         3418 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.073, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000071 DAVMJI010000000
VERSION     DAVMJI010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.073"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            8..232
                     /locus_tag="VYR58_002010"
     CDS             8..232
                     /locus_tag="VYR58_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3623098.1"
                     /translation="MLKRIRDLREDDDLTQEYIAKIVLNCTRSAYSKMEAGNRLISIN
                     DLIKLADFYKVSLDYLVGRVDNKEDHYSKK"
     gene            368..508
                     /locus_tag="VYR58_002011"
     CDS             368..508
                     /locus_tag="VYR58_002011"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623099.1"
                     /translation="MRQMIYNDTSDRSGCHRKRAASEILMMTSSVMPWRRLIKDKKEV
                     IF"
     gene            690..2477
                     /locus_tag="VYR58_002012"
     CDS             690..2477
                     /locus_tag="VYR58_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV3623100.1"
                     /translation="MSNNVEIIKANPLVTRRNDNSGSSSRRVAAYCRVSSDSDDQKNS
                     YDSQVRHYREYISQHQDWNLVDIYADEGISGTQVGKRQDFQRLISDCLDGKIDYIITK
                     AIARFARNTLDTLKYVRLLKDKQIGVFFEEENIDTLTMDGELLLTILSSVAQQEVENT
                     SAHVKKGLKMKMQRGELIGFQGCLGYDYNQDTKSISINEKEAKIVRYIFERYIDGIGG
                     KAIARELDELGYKTPRGLDHWQDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLINF
                     GEEDKYYIKNNHDAIISPEIFTQAQEIRLRRSGNKKTIANTKGKRERYSRMYPFSSRL
                     ECGFCGTVLSRRSWHSSSEYKKIIWHCTTSIKKGKKHCIHSKGIEEKAIENAFLQSYQ
                     QLFYENNNLTEDFLEIIKEELTDDTLKVELNKIVSKLNSLYKKEEKLVSMNLDGKISD
                     SVYEDKFNQIQIEKEKLLEEKVNLEVTLKSEVDIKSRLENFKEILTSQKTLTEFDKDI
                     FDSIVEKIIVGGINSDGEIDPAMLTIIFKTGDSSTKDAKSYKSKRKNAKIENDKLCFN
                     TVTDDEKKCTNKENNARRDGSTFVQTRCR"
     gene            2398..2745
                     /locus_tag="VYR58_002013"
     CDS             2398..2745
                     /locus_tag="VYR58_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623101.1"
                     /translation="MTKKSVQIKKTTHVETVALLSKLDVDKHISVEIELDEMDLTSAE
                     SKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIELREHYNKSKKDKQIIPQCTPEKE
                     EAIMDALRHFKMI"
     gene            2959..3192
                     /locus_tag="VYR58_002014"
     CDS             2959..3192
                     /locus_tag="VYR58_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HEV3623102.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
BASE COUNT         1364 a          416 c          640 g          998 t
ORIGIN      
        1 acaacaaatg ttgaaaagga ttagagattt acgtgaagat gatgatttga cacaagaata
       61 tattgcgaaa atcgttttga attgtacaag atcagcttat tctaaaatgg aagctggtaa
      121 caggttaatc tctataaatg accttatcaa acttgcagat ttttataagg tgagtctaga
      181 ctaccttgta ggtcgagtgg ataataaaga agaccattac tccaaaaagt agttggttaa
      241 gaaagcacat tgacaattga ataatccaaa atggtacttt cctcatttgt ggagcagatt
      301 tgaatggctc gccatgataa gagcgatttt aaaaccatca ataaaataga gcgatacttt
      361 atatgccatg agacaaatga tatacaatga tacttctgac cgttcaggct gccaccgtaa
      421 aagagcagca agtgaaattc ttatgatgac ttcatcagtc atgccatgga ggagattaat
      481 aaaagataaa aaggaagtga ttttttgaaa tcaaatttag aaaattatat agttgagcta
      541 gagatgctaa atctattatt cctacaaaaa cttattagcg aaaaagaata tgaaaaaata
      601 aagctgaaac tgcgtaaaat atacacaaat tagctgacct tttttattgg ttgcggtaaa
      661 ataaatgcag agaaatagga ggttaagcca tgtcaaataa tgttgaaatt ataaaagcaa
      721 atcctttagt aactagaaga aatgataata gtggttcttc atcgaggaga gtagcagcat
      781 attgtcgtgt tagttccgat agtgatgatc aaaaaaatag ctatgattct caagttcgtc
      841 attatagaga gtatatatca cagcaccaag attggaattt ggttgacatt tatgctgatg
      901 aagggatttc aggaactcaa gttggaaaaa gacaagattt tcaaagattg atttcagatt
      961 gccttgatgg aaaaatagac tatatcatta ctaaagctat tgctcgattt gctagaaata
     1021 cattagatac tctcaaatat gttcgtttgc ttaaagataa acaaattgga gtattttttg
     1081 aagaagaaaa cattgatact ttaactatgg atggtgagtt gctattaacg atattgagtt
     1141 cggtggctca acaggaagtt gaaaatacat ctgcccatgt taaaaaaggt ttaaaaatga
     1201 agatgcaacg tggagaactt attggttttc aaggttgtct tggttatgac tataatcaag
     1261 atacaaagtc aatatcaata aatgaaaaag aagccaagat agtacgttat atttttgaac
     1321 gatacattga tggtattggg ggtaaggcaa tagctagaga actagatgaa ctaggttata
     1381 aaactccgag aggtcttgat cactggcaag atacaacagt tttaggaatt attaaaaatg
     1441 agaagtataa aggtgatatt ttaatgggaa aaactttcac tgttgacccc attagcaaga
     1501 gacgtttaat aaatttcggt gaagaagata aatactatat taaaaataat catgatgcaa
     1561 taattagtcc agaaattttt acacaggcgc aagaaattcg attacggaga tcaggaaaca
     1621 agaaaacaat agcaaataca aaaggaaaac gagaaagata ttcaagaatg tatcctttta
     1681 gtagtagatt ggaatgtggt ttttgtggta ctgttctgtc tcgaagaagt tggcactcta
     1741 gttcagagta caaaaagatt atctggcact gtacaacatc tataaagaaa ggtaaaaagc
     1801 attgcatcca tagtaaagga atagaggaaa aagcaataga aaatgctttt ttacagagct
     1861 accaacagtt gttttatgaa aataataacc taactgaaga ctttcttgaa attataaaag
     1921 aagagcttac tgatgatacc ttaaaagtgg agttgaataa gatagttagt aaattaaatt
     1981 cgttgtacaa aaaagaagaa aaattagttt caatgaatct agatggaaaa ataagtgatt
     2041 ctgtatatga agataaattc aatcaaatac aaattgagaa agaaaaactt ttagaagaaa
     2101 aagtaaactt agaagtaact ttaaaatcag aagttgatat aaaaagtaga ttagagaatt
     2161 ttaaagaaat tttaacttca caaaagactc tgacggagtt tgacaaggat atttttgata
     2221 gtatcgttga aaaaatcata gtaggcggaa taaattctga tggagaaatt gatccagcaa
     2281 tgttgactat aatttttaaa acgggagatt cttcgactaa agatgcaaaa tcttacaaat
     2341 ctaaaaggaa gaatgctaaa atagaaaatg ataaattgtg ttttaatacc gtaaccgatg
     2401 acgaaaaaaa gtgtacaaat aaagaaaaca acgcacgtcg agacggtagc acttttgtcc
     2461 aaactcgatg tcgataagca cataagtgtt gaaattgagc tggatgagat ggatttgaca
     2521 agtgcggaga gcaaagcaac atatgctcaa atcaaagaat atgtttggaa taaatttgaa
     2581 ttaaaagttt cgacattata tattgcacag ataaaaaaga aatgtggaat agaattacga
     2641 gaacattaca acaagtctaa aaaggataaa caaattattc cacagtgtac acctgaaaaa
     2701 gaagaagcca tcatggatgc tttgagacac ttcaaaatga tttaatagaa aagaatgaca
     2761 gtatatgact ttctgcattt attacattcc tacttggtat aggaacagct attattcctt
     2821 tcttgcaagg tatcaattag aaaataggct caatataaag attgatagga tcatttttat
     2881 atttaaagga gcgttgaaat gattgataaa ggcaacaaaa aattttagga taaatttgct
     2941 aagttgtatg ccccttttat gaaaaaagat aaagaggttt atgataaagt ttgtgaatat
     3001 cttagtcctc atttgaataa agatatggag gtgcttgaac ttgcttgttg gtttcgtgtc
     3061 ataacagtta tagaggcaaa tagttatgta aatataagga gttcaagact tctaccaaag
     3121 tttaaaactc aaaaaataaa tagttggtgt gctgcttata gtatccattt taataatgga
     3181 tattgtaatt agcataccaa tgaatttaaa gattctttaa agagtcttat tttgtgatga
     3241 aaatttaata tgtaaatctc agacgataga aattaaaaac tctatcgtct tttttatact
     3301 caaaattagg aggtaaaaat ggtaaggata agaggtccca cttaaaacaa tttatggcaa
     3361 aataaggacg gaataacaca acaaattctc taaaacaaat cactaaatca atgtaaga
//
LOCUS       DAVMJI010000072         3408 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.074, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000072 DAVMJI010000000
VERSION     DAVMJI010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3408
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.074"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            275..1561
                     /locus_tag="VYR58_002015"
     CDS             275..1561
                     /locus_tag="VYR58_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV3623103.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            1576..1887
                     /locus_tag="VYR58_002016"
     CDS             1576..1887
                     /locus_tag="VYR58_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623104.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            2133..2861
                     /locus_tag="VYR58_002017"
                     /pseudo
     CDS             2133..2861
                     /locus_tag="VYR58_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            3242..3408
                     /locus_tag="VYR58_002018"
                     /pseudo
     CDS             3242..3408
                     /locus_tag="VYR58_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452046.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT         1086 a          562 c          733 g         1027 t
ORIGIN      
        1 tttccattat aggagcaaca gagtgggagt agtcatctaa ggactaattt atatattttt
       61 acgagtcagt atcttgggat actggttttt acttttttag actttttgac tacttgttaa
      121 aactggggta attttcgact gtttaatagt tattatgcaa agtctaaaag attagaattg
      181 tcaaaacaat ccgtctaggc ttgattttat cctttattta ctataaaatg agaaggaaaa
      241 atgtcaaact tttatattgc aaataggaga aattatgaca aaaacattaa aacgtcctga
      301 ggttttatca cctgcaggga ctttagagaa gctaaaggta gctgttcagt atggagcaga
      361 tgctgtcttt atcggtggtc aggcctatgg tcttcgtagc cgtgcgggaa actttacttt
      421 cgaacagatg gaagaaggcg tgcagtttgc ggccaagtat ggtgccaagg tctatgtagc
      481 ggctaatatg gttatgcacg aaggaaatga agctggtgct ggtgagtggt tccgtaaact
      541 gcgtgatatc gggattgcag cagttatcgt atctgaccca gccttgatta tgattgcagc
      601 gactgaagca ccaggccttg aaatccacct ttctacccaa gccagtgcca ctaactatga
      661 aacccttgag ttctggaaag agctaggctt gactcgtgtc gttttagcgc gtgaggtttc
      721 aatggaagaa ttagctgaga tccgcaaacg tacagatgtt gaaattgaag cctttgtcca
      781 tggagctatg tgtatttcat actctggacg ttgtactctt tcaaaccaca tgagtatgcg
      841 tgatgccaac cgtggtggat gttctcagtc atgccgttgg aaatacgacc tttacgatat
      901 gccatttggg aaagaacgta agagtttgca gggtgagatt ccagaagaat tttcaatgtc
      961 agccgttgac atgtctatga ttgaccacat tccagatatg attgaaaatg gtgtggacag
     1021 tctaaaaatc gaaggacgta tgaagtctat tcactacgta tcaacagtaa ccaactgcta
     1081 caaggcggct gtggatgcct atcttgaaag ttctgaaaag tttgaagcta tcaaacaaga
     1141 cttagtggac gagatgtgga aggttgccca acgtgaattg gcaacaggtt tctactacgg
     1201 tataccatct gaaaatgagc agttgtttgg tgctcgccgt aaaatccctg agtacaagtt
     1261 tgtcgctgaa gtggtttctt atgatgatgc ggcacaaaca gcaactattc gtcaacgaaa
     1321 tgtcattaac gaaggggacc aagttgagtt ttatggtcca ggtttccgtc attttgaaac
     1381 ctatattgaa gatttgcatg atgccaaagg aaataaaatc gaccgcgctc caaatccaat
     1441 ggaactattg actattaagg tgcctcaacc cgttcaatca ggagacatgg ttcgtgcatt
     1501 aaaagaagga ctcatcaatc tttataagga agatggaacc agcgtcacag ttcgagctta
     1561 agaaaggaaa aggaaatgat agaggcacag ggtttcttag tggataagca aacaagatgc
     1621 attcattacc atagcaagct ggatattatt gctttacaat gctatgattg taaaaagtat
     1681 tatgcttgtt atcggtgtca tgattcatta gaaaatcacc cttttgagcc gtatccctta
     1741 tctttgatac aggataagcc tattttatgt ggtgtttgtc taaaactact aacatataag
     1801 caatataaag aaagcttaag ttgccccttt tgtttttctc gctttaatcc aggttgccaa
     1861 aatcataagg aacgctattt taaatagcaa atcatctagt tttgaagtag gagaaaactc
     1921 aattccaaga gaaaatgaag taaatcttcc cacaataaaa cgcataatat caagattgtt
     1981 caatacctga tactatgcgt ttttaagatt ttaaagactt ttttccttta tctggtattt
     2041 tgactacttg ttaaaactgg gtcaattttc aactgtttaa cagttattat gcaaagtcta
     2101 aaagattaga attgtcaaaa caatccgtct agagtatgcg tgatgccaac cgtggtggat
     2161 gttctcagtc atgccgttgg aagtacgacc tttacgatat gccatttggg aaagaacgta
     2221 agagtttgca gggtgagatt ccagaagaat tttcaatgtc agccgttgac atgtctatga
     2281 ttgaccacat tccagatatg attgaaaatg gtgtggacag tctaaaaatc gaaggacgta
     2341 tggagtctat tcactatgta ttaacagtaa ccaactgcta caaggcggct gtggatgcct
     2401 atcttgaaag tcctgaaaag tttgaagcta tcaaacaaga cttggtggac gagatgtgga
     2461 aggttgccca acgtgaactg gctacaggat tttactatgg tacaccatct gaaaatgagc
     2521 agttgtttgg tgctcgtcgt aaaattcctg agtacaagtt tgtcgctgaa gtggtttctt
     2581 atgatgatgc ggcacaaaca gcaactattc gtcaacgaaa tgtcattaac gaaggggacc
     2641 aagttgagtt ttatggtcca ggtttccgtc attttgaaac ctatattgaa gatttgcatg
     2701 atgccaaagg caataaaatc gaccgcgctc caaatccaat ggaactattg actattaagg
     2761 tgcctcaacc cgttcaatca ggagacatgg ttcgtgcatt aaaagaagga ctcatcaatc
     2821 tttataagga agatggaacc agcgtcacag ttcgtgttta atgtagttgt ttagttttaa
     2881 aaaattatgc aaagctccat atacaacact taaacgagat taaagaatgg cgaaatccct
     2941 tgatgcgcaa gagattagct gtcctttttt attttttaag tgataaagtc ggagcttagg
     3001 tatcaaagcc tatcaaatta aacaaagaag tgatgtttag atattttgaa aaaaattaat
     3061 aagcagaaaa ctctctatta ttttgttgta gagagttttt tgttaataaa attttacaaa
     3121 atgacattta tatattgcat taagttagat atatgatata atgttgttaa aaagaggcgc
     3181 aactttttaa actcaataag aatcaaagag caaaccatga atattaatgg aggaataaaa
     3241 aatgtaagtt ataaatgtaa gtaagcatta tggtcattca atcattctca aagatataaa
     3301 ttttgcactt aacaagggtg aaattgttgg tctagtaggg agaaatggag ttggtaagag
     3361 tacgttgatg aaaattcttg ttcagaataa tcaaccgact tcaggtaa
//
LOCUS       DAVMJI010000073         3233 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.075, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000073 DAVMJI010000000
VERSION     DAVMJI010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3233
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.075"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..201
                     /locus_tag="VYR58_002019"
     CDS             <1..201
                     /locus_tag="VYR58_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623105.1"
                     /translation="RLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSVLL
                     LFSNFSVPFIKAKEYELFKNSK"
     gene            1334..1573
                     /locus_tag="VYR58_002020"
     CDS             1334..1573
                     /locus_tag="VYR58_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623106.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            1558..1836
                     /locus_tag="VYR58_002021"
     CDS             1558..1836
                     /locus_tag="VYR58_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623107.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            2125..>3233
                     /locus_tag="VYR58_002022"
     CDS             2125..>3233
                     /locus_tag="VYR58_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV3623108.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVAKQSQAER
                     DYDAAMKKSEAAKKEYEEAKKDLEEAKAAQKKYEDDQKKTEEKAKLVQKADEERQKAN
                     VAVQKAYLKLREAQEQLNKSPNNKKNAAQQKLKDALAHIDEVTLKQKEAEANFNKEQA
                     KVVPEADKLAETKKKAEQAEKKEPELAKKVAEAKAKAEEAEKKAVEAKQKVDAEKYAL
                     EAKIAELEYEVQGLEKELKEIDESDSEDYIKEGLRAPLQSKLDAKKAKLSKLEELSDK
                     IDELDAEIAKLEKDVEDFKNSDGEQAEQYLVAAKKDLDAKKAELENTEADLKKAVDEP
                     ETPAPAPAPKPAPAPAPTPEAPAPAPKPAPAPKPAP"
BASE COUNT         1175 a          463 c          635 g          960 t
ORIGIN      
        1 agattatttg acacaagtac tttaatgaag aggagaatat tttttctttt cgcattggat
       61 gttatagctt acttattttt aggatatctt ttagtgattc aaaaagcagg ctatttgttt
      121 tcggttttac ttcttttttc taatttttca gttccattta tcaaagcaaa ggaatacgaa
      181 ttatttaaaa atagcaagta atagaaacat aggttaaatc ttagaacggc ttaaaatcag
      241 atatgataaa gggaaatagt cttatctagg taactaagtg ctacaaacac agtcgaggat
      301 cacttgttag gattacattt taatcatgct taataagaat ggagaattcc tatggggatt
      361 gtattactct gaagtttcga ataccttagt tctcgtgatt ttgagctgtt ctagctttag
      421 aatccttcag aatgtaaaat tttaagcagt caaagactta gaatagcctg gaaacattta
      481 ttttatagca attctaggct tagaattgct catatatatg tatttgagct gctcgatagt
      541 taggacagct ctattctgag aaatctgagc tatcaatgct tcagaatagt atttcgcaaa
      601 tggtttttat tgaagaggtg attgttttat gatagtctaa aataaaactg atttaatgga
      661 gtaaatggag aatcgtcaca tgaaacattt ttttgcagga attggtgaga taaaacttgt
      721 tggctactta ttgtatatat gtgtaggact agcccttctt tttcatatat atgtcatagg
      781 ttcggaactg agttttgtga aaatagtgtt atctattttg ggagttatat ttgtaagtat
      841 gttaactatt gctcgaattt atcggacttt tctataaaga atagtttgga cttgaactgt
      901 atctaaaaac agaggttggt cgattatcag cctctttctt gtcgttgaaa agagtgagat
      961 atattgactt ttgaaaaaaa tgtcataatt gagttgggat aaacctaaaa gtaatatagt
     1021 agattgaatc tggaatagtc cgttatgact gttaaaatat ttctagaaat taatttgact
     1081 ttcctaatcg atttgttcac atcttgtttc aatctactat actttctcgt taaaccgttc
     1141 ggcaattcat ggtgacatgg acacatagta gtaagcacac tatgtggctt ggcagagcta
     1201 aaaactgttc ccttgcgata agcctaataa gcacaacata gggagttaga gaagccgact
     1261 ctaatcaacc actttgggca gtagtgagaa ctgccccgtg cttttttatt ttgagaaaat
     1321 atggagtttg tcgttgaaat tacttgattg tattttggac tatcaagaaa gattcaatgg
     1381 aaaaacatgt caagtatcaa cgaattataa gtatttagag attttcaaag tgaatttttg
     1441 cttgactgat ttacatcatt tatttgactt atacaaaatc acacgagatt atgctagtca
     1501 aacaaaacct gctattcaag ctggtgtttt tattttagaa gattttagaa atatcctatg
     1561 tacaatgatg taatcgaaag gatatcttta tatgagttta tcggtgatat tttctattct
     1621 aaaataataa gttgttgcat cgtagctagg gatttatcta aaaatactat gaaattggac
     1681 gtcatatttt ttgaggataa aaataaaaga tccgcagttt taggtttacg aagagacaaa
     1741 agcggagtat ttaaatcagt tactctacat tttacaagcg ctaagaaata tgctaaagtt
     1801 cgtaaaacag atgtgaaaga aatgaaatgg ctataaagat tgtccgcagg cttaagcttg
     1861 cgttttttgt tgtttaacga aattaaaaaa caagctctct catcggaaat gtttttatag
     1921 gaatgaagga agatgatgct atgtttaaaa agagaatcga aaagggcaaa agtagtatct
     1981 ttatctattt tttggagtag aagcttatga tatagaaatt tgtaataaaa atgtaatata
     2041 aaacatttga caaatattta cggggggagt atacttaata taagtatagt ctaaaaatga
     2101 ctatcagaaa agaggtaaat ttagatgaat aagaaaaaaa tgattttaac aagtctagcc
     2161 agcgtcgcta tcttaggggc tggttttgtt gcgtctcagc ctactgttgt aagagcagaa
     2221 gaagctcccg tagctaagca gtctcaagct gagagagact atgatgcagc aatgaaaaaa
     2281 tctgaagctg ctaagaaaga atacgaagaa gctaagaaag atttagaaga agcaaaagct
     2341 gctcagaaaa aatatgaaga cgatcaaaag aaaactgaag agaaagcaaa gcttgttcaa
     2401 aaagcggatg aagagcgtca aaaagcgaat gtggcagttc aaaaggcgta tttaaaactc
     2461 cgagaagcac aagaacaatt gaacaaaagt ccaaacaata agaaaaatgc cgctcaacag
     2521 aaattaaaag atgcattagc tcatattgat gaggtaacat taaaacaaaa agaggcggaa
     2581 gcgaatttca ataaggaaca agcaaaagta gttcctgaag cagataagtt agctgagact
     2641 aagaaaaaag cagaacaggc tgaaaaaaaa gaaccagaac ttgctaaaaa agtagcagaa
     2701 gctaaagcaa aagcagaaga agctgagaaa aaagctgttg aagccaaaca aaaagtggat
     2761 gctgaaaaat atgctcttga agctaaaatc gctgagttgg aatatgaagt tcagggacta
     2821 gaaaaagagc tcaaagagat tgatgagtct gactcagaag attatattaa agaaggtctc
     2881 cgtgctcctc ttcaatctaa attggatgcc aaaaaagcta aactatcaaa acttgaagag
     2941 ttgagtgata agattgatga gttagacgct gaaattgcaa aacttgaaaa agatgtagaa
     3001 gatttcaaaa actcagacgg tgagcaagct gaacaatatc ttgttgcagc taaaaaagac
     3061 ttagatgcta aaaaagctga attagaaaat actgaagctg accttaagaa agcagttgat
     3121 gagccagaaa ctccagctcc ggctccggct cctaaaccag ccccagctcc agctccaact
     3181 ccagaagccc cagctccagc tcctaaacca gctccggctc ctaaaccagc ccc
//
LOCUS       DAVMJI010000074         3177 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.076, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000074 DAVMJI010000000
VERSION     DAVMJI010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.076"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(<1..368)
                     /locus_tag="VYR58_002023"
     CDS             complement(<1..368)
                     /locus_tag="VYR58_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV3623109.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEIS"
     gene            complement(668..850)
                     /locus_tag="VYR58_002024"
     CDS             complement(668..850)
                     /locus_tag="VYR58_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV3623110.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIASELVAGLR"
     gene            909..2168
                     /locus_tag="VYR58_002025"
                     /pseudo
     CDS             909..2168
                     /locus_tag="VYR58_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(2284..3087)
                     /locus_tag="VYR58_002026"
     CDS             complement(2284..3087)
                     /locus_tag="VYR58_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV3623111.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYENATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
BASE COUNT         1111 a          563 c          530 g          973 t
ORIGIN      
        1 gatatttccc agcgtagggg attcgaaata ataatccctt ctttataacg ttctatgctc
       61 gaagaaatat gatccgttaa attaatatag ataatttcat caaaattatt acccaatgtt
      121 attttaccta ggttaattat tttttcggtg atgtacacca actccaaagg aacgttaata
      181 aacatctctg taaaacgggt catattatct ctatttttga gaaaaaaact tttctcaata
      241 tcaattggat ttactttatc tccagttttt cttccaaaag ctatgcccct tccaaaaaga
      301 agaatatcga tatctttttt actttgcgca attacggcat tgtggtttag tattcgtttt
      361 atgatcataa aatttccctt ttaaaataaa aggaacctac ttaaaaacat caagaaactt
      421 cttccgatgt gattaaatag gttcctgctc acttgtatta gtgataacat ccttttattt
      481 caatttttaa tggtgacatg aagcttaaat aattaataac tctgtaacca ttttcatttt
      541 atgatatttc aatctatttg tcaagtactt gtagaaattt ttttattttg tgtgattcga
      601 atgtgataat ggcaacagtc tcactaaaga aatgaaaatc atacatagaa atttttaaaa
      661 attttctcta tcgtaaacct gccactagtt cagaagctat actagctgat tccaaacgta
      721 atatggtcat ctcatctacc ttccctaata atggcattgc accataccaa acaatagtct
      781 tattcaccaa aagaataggc gttactattt ttgattgagt aaaagacact ttaattttct
      841 ggctcttcaa ctgtgaacta caccccaaaa gttagacaga aaaaatctaa cttttggggt
      901 gttttattat gaaactaact tatgatgata aagttcagat ctatgaactt agaaaacaag
      961 gatatagctt agagaagctt tcaaataaat ttgggataaa caattctaat cttaggtaca
     1021 tgattaaatt gattgatcgt tacggaatag agttcgtcaa aaaaggaaaa aatcgttact
     1081 attctcctga tttaaaacaa gaaatgattc ataaagtctg acatgaaggc tggactaaag
     1141 atagagtttc tcttgaatac ggtctcccaa gtcgtacgat acttcttaac tggctagcac
     1201 aatacaggaa aaacgggtat actattgttg agaaaacaag agggagagta cctgagagcg
     1261 gagaatgcca tcctaaaaaa gttaagagaa ctccgattga aggaggaaaa agagaaagaa
     1321 gaaagacaga aattgttcaa gaattaatga ctgagttttc gttagttctt cttctaaaag
     1381 ccattaaact agctcgttgg acctactact atcacttgaa acagctagac aaaacagata
     1441 aggaccaaga gcttaaagct gaaattcaat ccatttttat cgaacacaag ggaaattatg
     1501 gttatcgtcg gatttattta gaactaagaa atcgtggtta tctggtaaat cataaaagag
     1561 ttcaaggctt gatgaaagta ctcaatttac aagctaaaat gcgacagaaa cgaaaataaa
     1621 ggagacgttg gtaagaaggc agagaatctc attcaaggcc aatttgaagg atctaaaaca
     1681 atggaaaagt gctacacaga tgtgacagaa tttgccattc cagcaagtac tcaaaagctt
     1741 tacttatcac cagttttaga tggctttaac agcgaaatta tcgcctataa tctttcaact
     1801 tcacccaact tagaacaagt acaaacaatg ttggaacagg cattcacaga gaagcactac
     1861 gagaatacga ttctccatag tgaccaaggc tggcaatacc gacacgattc ttatcatcgg
     1921 ttcctaagag taagggaatt caagcatcta tgtcacgcaa gggaaacagc caagacaacg
     1981 gtatgatgga gtccttcttt gggattctga aatcggaaat gttttatggc tatgagaaaa
     2041 catttaaatc acttaatcaa ttggaacaag ctattgtaga ctatattgat tactacaaca
     2101 ataaacgaat taaggtaaaa ctaaaaggac ttagccttgt gcaatacaga actaaatcct
     2161 tcggataaat tatttgtcta actttttggg gtcagtacac ctaaaacttt gatgatatac
     2221 gttttcttgt gagaatattt acttcatttt tgcctaaaat tcaatgttta ctcagtattt
     2281 ggattatgaa aaatcgaggt ctaaatctag atacattttt tctgaagaca aatcattttg
     2341 accaccgagc aagagatttt caaaaaaagc tgttaaaaac tcagaacgtc gctgtaaaat
     2401 ctttgcatta tctaatacca aggcatcacg aaaatatttg gaatgttgct gaaatggtgt
     2461 attatcaata tcaaaaccaa actcacgaag atactgaatc aaaaagaccg ttactgtccg
     2521 agtgtttcct tcgcgaaatg gatgaatctg ccagattcct gaaataaaat gctggatttg
     2581 tttaaccaca tccgcctgag ttagtgtcgc atatgcaact tgtttttcct gattaaaatc
     2641 ataatctaag gtcatttgaa tcatggagta atcagagtac acaacacttt caccattcaa
     2701 aacaggttca ttctttgtga tattggtctg acgaaattgc cccaccggaa tagagggttc
     2761 aaatatatct tgaaacaact ccttatgaat agcaagtaag gtcgcaggac taaagctaaa
     2821 gcctcttcga gacaatagtt ctacaatacg tagagaaacc aagtctgcct cttccgtact
     2881 tgcatcaata gtatggtgat aagccgttgc attctcataa acctgctcat aagtcagttc
     2941 tccccgggac tgtttctcag ccaaagattc catatacgct gatggcacta gattgtcaac
     3001 tttctgcaga ccaaaaccta tccgccataa atcacgcttc gcttcataag acaagtttgg
     3061 attgtcaatg ttgtaagttg attgcataga aatatccttt caattgtttt tcttcattac
     3121 cagtaaatca cgaaattggt tggaaactgg cttaaactat aaaaagtcct cacaata
//
LOCUS       DAVMJI010000075         3127 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.077, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000075 DAVMJI010000000
VERSION     DAVMJI010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3127
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.077"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..609
                     /locus_tag="VYR58_002027"
     CDS             <1..609
                     /locus_tag="VYR58_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV3623112.1"
                     /translation="MPYNLQYTVEVKNGSLIIPHYDHYHNIKCEWFDEGLYEAPKGYT
                     LEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPSEEKPQTEKP
                     EEETPREEKPQSEKPESPKPTEEPEESPEESEEPQVETEKVEEKLREAEDLLGKIQDP
                     IIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESK"
     gene            1031..1411
                     /locus_tag="VYR58_002028"
     CDS             1031..1411
                     /locus_tag="VYR58_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV3623113.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            1869..2582
                     /locus_tag="VYR58_002029"
     CDS             1869..2582
                     /locus_tag="VYR58_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV3623114.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2596..>3127
                     /locus_tag="VYR58_002030"
     CDS             2596..>3127
                     /locus_tag="VYR58_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623115.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSN
                     FDDFLEKNYLKTIWQVS"
BASE COUNT         1061 a          495 c          605 g          966 t
ORIGIN      
        1 atgccttaca atcttcaata tactgtagaa gtcaaaaacg gtagtttaat catacctcat
       61 tatgaccatt accataacat caaatgtgag tggtttgacg aaggccttta tgaggcacct
      121 aaggggtata ctcttgagga tcttttggcg actgtcaagt actatgtcga acatccaaac
      181 gaacgtccgc attcagataa tggttttggt aacgctagcg accatgttca aagaaacaaa
      241 aatggtcaag ctgataccaa tcaaacggaa aaaccaagcg aggagaaacc tcagacagaa
      301 aaacctgagg aagaaacccc tcgagaagag aaaccgcaaa gcgagaaacc agagtctcca
      361 aaaccaacag aggaaccaga agaatcacca gaggaatcag aagaacctca ggtcgagact
      421 gaaaaggttg aagaaaaact gagagaggct gaagatttac ttggaaaaat ccaggatcca
      481 attatcaagt ccaatgccaa agagactctc acaggattaa aaaataattt actatttggc
      541 acccaggaca acaatactat tatggcagaa gctgaaaaac tattggcttt attaaaggag
      601 agtaagtaaa ggtagcagca ttttctaact cctaaaaaca ggataggaga acgggaaaac
      661 gaaaaatgag agcagaatgt gagttctagt tctcattttt ttcatgaaaa tgtgcaaaat
      721 atagtagatt gaaactagaa tagtatacct ctacttctaa aacattgtta gaaatcgatt
      781 tgactgtcct gttcttattt cattttacta tatcttaaca gatagtgtaa ataaagataa
      841 actatttact ggctaattaa tcagttaaac actagttaag gagtaatgat gaaaaaaaga
      901 acaatactat tattgatggc cagtctgtta gctcttgtct taggagcatg tggtttcttg
      961 gacatattga tcctggatca ttctcatcag gattactctt tactgctatt ttagaaactg
     1021 gagtggtttg atggaaagta ttggtattgg tcttgttatc gtttcacatt ccaaacatat
     1081 tgcagaaggt gttgttgaac tgattagtaa agtagctaaa gatgttccga ttacttatgt
     1141 aggaggaacc gagggcggag gaattggaac gagttttgat caagtagata gggttgtttc
     1201 cgaaaatcca gcagatactt tacttgcctt ttttgaccta ggttctgcta aaatgaactt
     1261 aaaaatggtg actgatttca gtgataaaag tatcatcatc aacagggttc caattgtaga
     1321 aggtgcctat aatgcagctg ctcttcttca ggctggtgca gaactgtcag ttattcaaat
     1381 acagttagcg gagcttgaaa tcaataaata aggaatttta ctataactct ttttatagat
     1441 aagctattga ttatctcaac tataaaatgt taagtaaatg atttcaaaat cagaaaggga
     1501 ttgctttatg cagttccttt ttattttaac aggagtgaaa ctatagtgtt tctaaattgt
     1561 gaatcaatca aaactgattg tgatggggct attctagctt tagaatcctt caaaaattaa
     1621 aatttaaggc aatcaattac ttggaagagt atgaaagcat ttagtttata ggaattctag
     1681 gtctagaatt acatatgtat ttatgaagac ggggtgttcg atagttagta ttgttctatt
     1741 ctgaaagatt tgagctgtca gttgtataga aagtgttcga atttttttaa gtgattaaat
     1801 tagttaattg tatgaggtgc tttatgatat aatgttctta atgaattttc agaaaggaaa
     1861 acctcaaatt gttctacaaa tttctactct tcgacctcga ccacactctt cttgattttg
     1921 atgctgctga ggatgtggct ttgacccaac ttctaaaaga agaaggagtt gcggatattc
     1981 aggcttataa agattattac gttcctatga acaaggctct ctggaaagac ttggagctga
     2041 agaaaatcag taaacaagag ttggttaaca cgcgcttttc tcgtttattt tctcattttg
     2101 gacaggaaaa agacggtagt tttcttgccc agcgttacca attttatctc gctcagcagg
     2161 gacaaacact atcgggcgct catgatctct tggacagcct cattgagcgt gattatgact
     2221 tgtatgctgc gacaaatggc attactgcca ttcagacagg acgtttggct caatctggtc
     2281 tagtacctta tttcaatcaa gtctttatct cagaacagtt gcaaactcaa aagccggatg
     2341 ctctctttta tgaaaagatt ggccagcaaa ttgctggatt tagtaaagaa aagacgctga
     2401 tgattggaga ttctctaacc gccgacattc aaggtggcaa taatgcgggg attgacacta
     2461 tctggtataa tcctcatcac ctcgaaaatc acacacaagc ccagccgact tacgaagtct
     2521 attcttacca agacttgctg gattgtttag ataaaaatat tcttgaaaag atcacatttt
     2581 aaaggagatg agctaatgac tacaaaaaaa gctaatatta ctattgaaga gtacattgaa
     2641 atgtctgaag ttgattttaa tgaagctgtt aattatgaat ttacatctga cacttgtcaa
     2701 ttagcaaata gtatttatca atctcttttt aagttttttg ataagaaaaa tttctctggc
     2761 gatttaattt ttacttggaa atctccatca ttagtcaaag aaggggatta tattgggaga
     2821 agggattcac aagtagataa tcttagagta ataggaaata tatttccgaa ttatcttact
     2881 aatcgaaaat atagcctcaa tatgaatcgt aatggctgta tgggagattt tcctcatgac
     2941 ttttttgata tatacctaga tcatgtagca aaatatgcct acgaacaaaa agttaataat
     3001 attaaagagt attatccttt aaaaagagcg attttacacc aagagaatgc attgtatttt
     3061 cgattgtttt ctaattttga cgacttttta gaaaaaaatt atttaaagac tatatggcaa
     3121 gtttcta
//
LOCUS       DAVMJI010000076         3112 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.078, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000076 DAVMJI010000000
VERSION     DAVMJI010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.078"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(171..641)
                     /locus_tag="VYR58_002031"
     CDS             complement(171..641)
                     /locus_tag="VYR58_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV3623116.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFTPPFFFEE"
     gene            complement(658..2931)
                     /locus_tag="VYR58_002032"
     CDS             complement(658..2931)
                     /locus_tag="VYR58_002032"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV3623117.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFAYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVSLPHKIELEKPQLNLVQPQGKAELVAEAEEKLTHINSSYTLNDY
                     FLPRGFATLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNDRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT          914 a          550 c          698 g          950 t
ORIGIN      
        1 aaggcgatgt tgacgcggat tgaagagatt ttcgaagagt ataaatcttc ctaggataaa
       61 gcaaaacgca tagtatcaag ggttttcaac acttgatact atgcgttttc tgatgttaaa
      121 gactttctac caggtttttt aaaagcataa ttgttagttg tagtcattta ttattcttca
      181 aagaaaaatg gtggggtgaa ttttttcagt tcttcaaagc acttttgagc agtatctgca
      241 tcttcacaga tgataagaca gacatcatta ccacaaaggg tagcgatagc gtcagggaag
      301 ctcaaagtat caatgataga accaaaggat tgagccagtc caggaagggt ttttagtagg
      361 acttggtgtt gaactgggcg catccagaca agggcgtctt ccatgtagag ttcgagacgt
      421 ttttcccatt ttgagatgga accattgtta agaacataat aagcgctatc ttcttcgcgg
      481 acttttgata ggttcatatt tttgatgtcg cgtgagaggg ttgcctgggt tacttgaatg
      541 tcgttcttag caagaagggc ttgcaactca gcctgtgtat gaatcttgtt ttttgtgata
      601 agagcgcgta taagttggtg gcggtgttct gatttattca taataatgta actcctttta
      661 gcaaggtaag gtaagcatgg actgagcgag gtcgacagtc aagtggtagt ctgtattgtc
      721 acggatggtg atttcaaagt cagtagtata gaggactaaa cggagagtgt ctccttcttt
      781 tagcttgtaa atagttggct gcagttcaaa ttgaacgtcc atccattcat ctgcagtaat
      841 atcctctact aacagtaaat catttctatt ttgtaaatta aggtaacctt ttgtcacgac
      901 tcgttgtgcc tctggtctaa atggcaattc acagagattt tccaacatgt gatagcgacc
      961 gttgtcaatg gttctagcac ttaaaatagc tggataaggt tgtaggtatt tcttttgccc
     1021 aaattctagc agttgggcag ataagagccc cttgtttgta ctggatttga tacgaagatt
     1081 gagctgagcg cgaccgttta ggtggagatc tttagtcaca ggaaggttaa tagtaatctg
     1141 attagctttc ccttgataga gctctgtatt gaaggtttgg tatgtcttac catagcgctc
     1201 aaaatcctta tctgggtact ggttttgaat agcttgctct tcttgaccaa gtgagaaggt
     1261 ttcacagttt tcttgcccac cgaagttatc aagtgataac caagtctgtg gagctgtatt
     1321 gtcctgccag ataacagtag gaagttgaaa gtctgtttcc tgtcctagta atttcttggt
     1381 caataaggca tttatggact cacggaagtc aattgattgc caattgttca tgtaaacatg
     1441 ggcaccatta tggaaaaaga gatgcttgtg tatatgagta ggaagagcat ggaacatctg
     1501 gtaaacatga agtggtttga cattccaatc ctgagaacca tgagtaaaga caacctctgc
     1561 ctttacttta tgggcattga gcagataatt gcggtcatgc caaaactgat tgtagtcccc
     1621 agtttttcgg tctagctgag ctttcacttt ttctaagtca gcttggtgag cttcattgcc
     1681 acggatatag tcgccagcta agagattacg agaataggtt aactcagcaa gggagtcaaa
     1741 gtcctcacct ggataaccac ctgggctagt caccagaccg ttttcacggt agtagttgta
     1801 ccatgatgaa attcctgcct cggcaatgat aacttctaaa ccatcgactc ctgtagtcgc
     1861 aagaccattg gacatggtac ctagatagga aagtcccgtt gtagcaactt ttccgtttga
     1921 ccaatcagcc ttgacttgac gctggcgcgt gtgatcagta aaggcacggc aacggtcgtt
     1981 aagccaatcg atgacatttt tataagcctc gatttgctgg tagtctccat tagtcatgaa
     2041 acctgtcgag tctttggtac caacacctga gacatagaga gtggcaaagc ctctcggaag
     2101 gaagtagtcg tttagtgtat agctagagtt gatgtgagtt agcttttcct cagcctctgc
     2161 tacaagctca gctttacctt ggggttggac gagatttagt tgaggtttct ctagctcaat
     2221 cttgtgagga agagaaacct caagctcgcc ctccatcttg tagagagcct tgtcactagc
     2281 cttatcattg gttccctgat gataagggct ggctgtcatg atggcaggga tttttccatc
     2341 aaaacgaggg cgaataatgc taacctttac taggtctgat agcccttttt ggtcagtatc
     2401 gacacgagac tcaacgtaaa cgacttcacg aatgacatcc tggttagaaa aagtagccaa
     2461 actcttgccg ttaaagtagt ggtagtcatt atcctccgga ataagaccat cactaacaag
     2521 ttggtcgata agagtatttc cttttttggt gcgagtattg agtaactgat agagattttc
     2581 aatcaagtca ccatatataa tgggaaatcc agtttcttta cgaaaaacgt cactatcttc
     2641 gaagtcaacc aaataagcaa agcctaaaag ttgaaaagca acagtataaa aaatatctgc
     2701 tgtcagttca tcttctgatt gaaaaaatgt cagcaggtct gtttttttat cagctgctag
     2761 gatggaaagt gggtagttgg tgtcttgata agtgaaaaag aaacgacgta aaaaggtttc
     2821 aagtgagtct ttgtgattgg ctgtattttg taaatcaaag ccacattttt ttagttcaga
     2881 taagacattt tcttttggaa aattgatata actatattga ttaaaacgca tagaacctcc
     2941 atatagaatg acagttaagg ttattatatc aaaaaaaaag cagaaaggga attgttaact
     3001 tcaaaaggaa ataatccaat aaaaatgaat aaagtactaa attcaatata gagaacagag
     3061 taacaataag aataatagat agggtataaa agttctagga gatttatagt at
//
LOCUS       DAVMJI010000077         2941 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.079, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000077 DAVMJI010000000
VERSION     DAVMJI010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2941
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.079"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            42..974
                     /locus_tag="VYR58_002033"
     CDS             42..974
                     /locus_tag="VYR58_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV3623118.1"
                     /translation="MSGAVVKNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEY
                     AESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEE
                     GKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPI
                     YPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYH
                     ENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLT
                     KTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            1031..1828
                     /gene="psrA"
                     /locus_tag="VYR58_002034"
     CDS             1031..1828
                     /gene="psrA"
                     /locus_tag="VYR58_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV3623119.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1839..2447
                     /locus_tag="VYR58_002035"
     CDS             1839..2447
                     /locus_tag="VYR58_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV3623120.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(2395..2940)
                     /locus_tag="VYR58_002036"
     CDS             complement(2395..2940)
                     /locus_tag="VYR58_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV3623121.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT         1054 a          442 c          484 g          961 t
ORIGIN      
        1 ttctttcatc aaatgtagtt tattctcaat ttctatctct aattagtgga gctgttgtga
       61 aaaacttgaa tagtgataaa gttgcttcta ttcttatccc tctcccccca ctatccgaac
      121 aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
      181 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      241 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      301 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      361 agaaagattt ggacatttct attgtttccc aaggagatga taactcttat tatgaggaag
      421 taccttgtga aataccagaa agttgggaat gggtgaggtt aaacgatata acctcctaca
      481 ttcaaagagg gaagtctcca aaatattcaa atattcctat ataccctgtg attgctcaga
      541 aatgtaatca atggtctggc ttttctattg acttagcaag atttattgat cccgaaacag
      601 ttcatagtta ccagaaagaa agattactaa gagatggtga tttaatgtgg aattcaacag
      661 gtctaggtac gttaggacga ttagctattt accatgaaaa taaaaatcct tatggctggg
      721 ctgttgcaga tagccatgtt acagttataa gagtcttatc gggagttatt aattgccatt
      781 tcatctataa ttttctttcc tctcctattg ttcagtcagt tattgaagaa aaagcgtcgg
      841 gtagtacaaa acaaaaagaa ttattaacga aaactataaa agaatattta atccccctcc
      901 caccccttcc tgaacaatcc agaatcgttg ataaaatcga acaatttttc gcccatattg
      961 acgcactaat ttagtataat agttttacgt gcggtggaat ttctatcaaa cataagatag
     1021 gagttttacg ttgaaagatt ttgaattaca tttgaagaaa gctggtttag ctgaaaatac
     1081 tgtgcgttcg tacctttatg gtgttcgatt tttcttggag aattacgaac tcaaaatgga
     1141 agatttattt gaatacaaag gatatttatt agacaatttt aaacctaaaa ctgtcaattt
     1201 gcgactacaa ggagtaaata aatatctggc ttttattggt catgatgatt tgaaattaaa
     1261 atttgtcaaa gtacagcaaa aaccattttt agaagatgtc attagccatg ctgattacct
     1321 ttttcttaaa cgtagtttga aaaaagatgg tattttaaaa tggcattttg tcgtttggtt
     1381 tttaggtgca actggggctc gtgtaagtga acttattaaa ctaaaagtag agcatgtaga
     1441 aatcggttat tttgacattt actcaaaagg tggtaaaatt cgtagactgt acattcctaa
     1501 aaaattaaga aatagttgtc ttagttggtt agaatcagaa aatcgccgaa gtggttattt
     1561 atttttgaat aaatttaacg aaccaattac agcaagagga gttgctcaac agttaaaaaa
     1621 ttatgctgat aaatacaaaa tgaatcctaa agtaatttac cctcattctt ttaggcattt
     1681 atttgctaag aattttttag cgaagtataa tgatattgcc ttgcttgcag atttgatggg
     1741 acacgaaagt atagaaacta ctcgaattta tctaaggaaa acagctactg aacaacaaaa
     1801 tattgtagat aaaattgtta attggtaaaa aataacaggt ggtcaaactg actacctgct
     1861 atttttgtga ttatggctct tattatggga acaaagacga aacaacctct tatcctatat
     1921 atgaaatccc agaagcatgg agatatatta aatttgctag cctagttaac ttcagaatag
     1981 gaaaaactcc tccacgcagt gaagctactt tttggggaac tgaaatacct tgggtatcta
     2041 tatcagatat gcctatatct ggttatgtaa ctaatacgag agaatctatt tctaaattag
     2101 cattaaaatc aaagaaaata gacatttcac ctaaaggaac tttattaatg agttttaaat
     2161 tatctattgg aaaagttgcc atattggata ttcctgccac tcataatgaa gccattatat
     2221 cgatattccc ctatgctaat aaagaaaata ttatcagaga ttacttaatg atatttttgc
     2281 cacttatctc tactttaggt gattcaaaag atgctataaa agggaaaaca ttaaatagta
     2341 ccagtatctc cgaattatta atccctattt ctaatcatga agagatgaaa agaatcattt
     2401 ccaaagttga tttacttttt caaaaagttt ctcaactttt tgagtaataa gttcctgttc
     2461 ctcaaaagga gctaacggaa ttaatagctc gcttagtgta gttttaggaa tattatataa
     2521 agcttgacct gatagtttag ttattgcttt caattgttta taaaataacg gagaggacaa
     2581 gttaaataat agaaattttg aaataatctc tgaactttcg aatggtgtta attggaaaat
     2641 aaatccacca gccacaacac catcatagtc tttatcgatt cttgcaaact ttccaatatg
     2701 ttctaaagag gttgatacag gtgttattag ctgattatgt tttaaataaa cttgttcaga
     2761 ggagatgaat tgtgtatcaa tgtagtaatc attatccaac agagaaaatt ctaaaggctt
     2821 aatattacca ccacgtataa ttctaacacc tttattatta atgcttaaat cgcccttctt
     2881 gtaagaaaga cctgtattca ttgaaaaaat atcttttatt tttataacaa cccaattcat
     2941 a
//
LOCUS       DAVMJI010000078         2927 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.080, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000078 DAVMJI010000000
VERSION     DAVMJI010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2927
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.080"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(130..663)
                     /locus_tag="VYR58_002037"
     CDS             complement(130..663)
                     /locus_tag="VYR58_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV3623122.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(752..1528)
                     /gene="recX"
                     /locus_tag="VYR58_002038"
     CDS             complement(752..1528)
                     /gene="recX"
                     /locus_tag="VYR58_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV3623123.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1566..2921
                     /gene="rlmD"
                     /locus_tag="VYR58_002039"
     CDS             1566..2921
                     /gene="rlmD"
                     /locus_tag="VYR58_002039"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV3623124.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          924 a          528 c          536 g          939 t
ORIGIN      
        1 gcataaatct ctttctagta atgtgttgta actctgctat aatggattta ttcctttttg
       61 tatttacaca atttatttta tactaccaaa aaaacaaggt caggattttg ttcctgacct
      121 ttgacaactt taccgattct ttagttctac atagcgcttg taccaaatgt ttacataggc
      181 ttctgagaaa ggaccacgtc cattgttaat ccaatcaaca agaattttga catgttcttt
      241 taaaatatag tccaagtcat cagaataatt cattttgcgt ttgtgacgct cgtattcttc
      301 aacgtccaag agacgttttt ccccatctgt aaaaatttta acatccaaat cgtaatcaat
      361 atacttcagt gcttcttcat ccagatagta ggggctagcc atattgcaat agtaagaagt
      421 tccattatca cgaatcatgg caatgatatt aaaccaatat ttcttgtgaa agtaaacaat
      481 agccggttct cgagtgaccc aacgacgacc atcactttcg gtaacaagtg tatgatcgtt
      541 gacaccaata atggcgtttt ctgttgtttt tagtaccatg gtgtcccgcc aagttcggtg
      601 gagactccca tcatgcttat aactttgaat tgtaataaag tcgccttctt ttggaagctt
      661 cataactaac caactttcta caatttataa gtttatcatt tactattgta ccataaaatt
      721 acctaaaatc tgtgaatttc acttggaaat attaaagata ttctctaaga gcgcttgcta
      781 tatccgaaaa atcgtagccc tttcgtgcta aaacttgagt taaacgctgc ttcagttcgt
      841 atccttcata ctttcgagca tacttagtat attgcttatc aagttccttg aagatgagtt
      901 cttgagtcgt ttcttggtca acttggctat ctaagtcgtc aaaggcaatt ttagcatcag
      961 aataagagaa gcccttgtta gtcaagttct ggataatctt atcttgcagg gcacgagctg
     1021 gaagttttcc ctcatatttt ttcaatagtt tattggctac acgttgagca acttcagaaa
     1081 aatcaaattc tttcaagttc tcttctatag tagattttga aatccctttt tgagatagtt
     1141 tctgagtcag cacataagga cccttgtctc ctgaaagttg attggtattg atgatagcat
     1201 aagcgtactg accatcatta atccacttat cttctttaag attagcaata acttgagaaa
     1261 cgatgttttt atcaatatcg tattttttca gatattctct gacttctttt tcagtgcgtg
     1321 ctttaaagga taagtggtag agagcgagat tcttaccata agaaaattga gcaaagtctt
     1381 gaatctcttt caattcctct tcgcttatca ccttatctct cgataacata aaacgaacaa
     1441 ttgtatcttc ggtgatatag catttgtcgc cattatcaag ctccatcagg tagagtcttt
     1501 ttttcttttc aagttttgtg attttcatag ctctattata actcaaaatg tgataagata
     1561 ggggtatgaa tctgaaagtg aaacaaaaaa taccattaaa aatcaagcgc atgggaatta
     1621 acggtgaggg aatcggcttt taccaaaaaa cattagtctt tgtaccagga gctctcaaag
     1681 gcgaagatat ctattgtcag attacttcta ttagacgcaa ctttgttgaa gcaaaattac
     1741 tgaaggtcaa caagaagtct aaatttcgaa ttgtgccatc ttgtactatt tataatgaat
     1801 gcggaggctg ccaaatcatg cacctgcatt atgataagca gctggagttc aagacggact
     1861 tacttcatca agcgctgaaa aaatttgctc ctgcaggata tgaaaattat gaaattcgtc
     1921 caactattgg aatgcaggaa ccaaaatatt acagagctaa gttacaattt cagactcgaa
     1981 aatttaaaaa tcaggtcaag gcgggcttat atgcacaaaa ctctcactat ttagtagagt
     2041 tgaaagactg cctggtacaa gataaggaaa cccaagtgat tgctaatcgc ttagcagaat
     2101 tacttactta tcaccagatt ccaatcacgg atgagagaaa agttctaggt gtccgtacta
     2161 ttatggtccg acgcgcgaga aagaccggac aggttcagat tattattgtt acaaaccgcc
     2221 agcttaattt aactcaattg gtaaaagagt tggttaaaga tttcccagaa gttgtgacag
     2281 tagctgttaa tacaaataca gctaaaacca gtgagatata tggtgaaaag acagagatta
     2341 tctgggggca agagagtatt caagaaggtg tactcaatta tgaattttca ctatcccctc
     2401 gagcttttta tcaactaaat cctgagcaaa cagaagtcct ctatagcgaa gcagtaaaag
     2461 cgctggatgt tgataaagaa gaccatttga ttgacgctta ttgtggagtt ggaacgattg
     2521 gatttgcctt tgcaaagaaa gttaaaacac tcagaggtat ggatattatt ccagaagcta
     2581 ttgaagatgc caagcgaaat gctaaaagaa tgggatttga caatactcat tatgaagctg
     2641 gaacggcaga agagattatt cctcgttggt acaaggaagg ctaccgagca gatgctttga
     2701 ttgttgaccc accacgtaca ggtctggatg ataagttatt agatactatt cttacttatg
     2761 taccagaaaa aatggtttat atttcttgta atgtttcgac cttggctcgt gatttggtac
     2821 gcttagtaga agtctatgat cttcattata tccagtcggt cgatatgttc ccacatacag
     2881 ctcgaactga agctgttgta aaattaataa aaaaagttta aaaaagt
//
LOCUS       DAVMJI010000079         2883 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.081, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000079 DAVMJI010000000
VERSION     DAVMJI010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2883
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.081"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            337..1683
                     /gene="gdhA"
                     /locus_tag="VYR58_002040"
     CDS             337..1683
                     /gene="gdhA"
                     /locus_tag="VYR58_002040"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV3623125.1"
                     /translation="MTSAKEYIQSVFETVKTRNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(1762..>2883)
                     /locus_tag="VYR58_002041"
     CDS             complement(1762..>2883)
                     /locus_tag="VYR58_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV3623126.1"
                     /translation="CGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMM
                     VAETSIVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDF
                     SCLPEIMSWDEYAFTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLKYDRAVRCRV
                     KIITMDMFSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHEYK
                     AIKRYWKLIQQDSRKLSDKHFYRPTFRMHLTNKEILNKLLSYSQDLKHHYQLYQLLLF
                     HFQNKEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNL
                     IKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSQA"
BASE COUNT          884 a          511 c          585 g          903 t
ORIGIN      
        1 actattatat atactttttt attttagtct agtataaata ttgctttcct ccaaaatggt
       61 catagtttta ctggcaaatc taacatatca cggataaatt aacaagtgat ttctgaattg
      121 ctaaacattt tcttttctta tagcatacca tactttaaga ttttgtcttt gagaaagata
      181 tttccaagaa aaacgttcgt ttttttatct attttcaaaa aacccaaaaa ctgaattgaa
      241 agaattttta gaaaatttct gttttttctt tacagtgaaa aaaaattctg ctataatgtc
      301 ttatgtaata aaatatgaca ataaaaggag aacgatatga catctgctaa agaatatatc
      361 caaagcgtgt tcgaaactgt aaaaactcgt aacgggcacg aggctgaatt cctccaagct
      421 gttgaagaat ttttcaacac tttggaacct gtatttgaaa aacaccctga gtatatcgaa
      481 gaaaatatct tggcacgtat tactgagcct gagcgcgtgg tttctttccg tgttccttgg
      541 gttgaccgtg atggaaaaat tcaagtaaac cgtggttacc gtgttcaatt caactcagct
      601 gttggaccat acaaaggtgg acttcgtttc cacccaactg taaaccaagg gatcttgaaa
      661 ttcctcggat ttgaacaaat ctttaaaaat gtcttaactg gacttcctat cggtggaggt
      721 aaaggtggat cagacttcga tcctaaaggt aaaacagatg ctgaagtgat gcgcttctgc
      781 caaagcttca tgactgaatt gcaaaaacac atcggaccat cacttgacgt acctgctggt
      841 gatatcggtg ttggtggacg tgagattggt tacctttacg gtcaatacaa acgtcttaac
      901 caatttgatg ctggtgtctt gactggtaaa cctcttggat ttggtggtag cttgattcgt
      961 ccagaagcaa ctggttacgg tttggtttac tatactgaag aaatgctcaa agctaacggt
     1021 aacagctttg ctggtaagaa agtcgttatt tcaggttctg gtaacgttgc tcaatatgct
     1081 cttcaaaaag caactgaact cggtgcaact gttatttctg tttctgactc aaatggttat
     1141 gtcatcgatg aaaatggtat cgacttcgat cttttggttg atgttaaaga aaaacgtcgt
     1201 gctcgtttga ctgagtatgc agctgaaaaa gcaactgcaa cctaccacga aggtactgta
     1261 tggacttacg ctggaaacta tgacattgct cttccatgtg ccactcaaaa cgaaatcaac
     1321 ggtgaagcag ctaaacgttt ggttgctcaa ggcgttatct gtgtatctga aggtgccaac
     1381 atgccgagcg accttgatgc catcaaagtt tacaaagaaa atggtatctt atacggacct
     1441 gcaaaagctg ccaacgctgg tggtgtagcc gtttcagctc ttgaaatgag ccaaaacagt
     1501 cttcgcctct catggactcg tgaagaagtt gatgaccgtc tcaaagacat catgacaaac
     1561 atcttcaaca cagctaaaac aacttcagaa acatacggtc ttgataaaga ctaccttgca
     1621 ggagctaaca ttgctgcctt tgaaaatgta gcaaatgcca tgattgcaca aggtattgtt
     1681 taagatttat ttactcaatc ctcaatcact acgattgggg atttttaggg ctctttgtca
     1741 actgtagtgg gttgaagtca gctaagcttg agaaaggaca aattttgtcc tttctttttt
     1801 gatattcagg gcgataaaaa tccgtttttt gaagttttca aagttccgaa aaccaaaggc
     1861 attgcgcttg ataagtttga tgagattatt ggtcgcttcc aatttggcgt tagaatagtg
     1921 tagttgaagg gcgttgacga ttttctcttt gtcctttaga aaggttttaa agacagtctg
     1981 aaaaagagga tgaacctgct ttagattgtc ctcaatgagt ccgaaaaatt tctccggttc
     2041 cttattctga aagtgaaaca gcaagagttg atagagctga tagtggtgtt tcaagtcttg
     2101 tgaatagctc aaaagcttgt ttaaaatctc tttattggtt aaatgcatac gaaaagtagg
     2161 gcgataaaaa tgtttatcgc tgagtttacg actatcctgt tgtatgagct tccagtagcg
     2221 cttgatagcc ttgtattcat gagactttcg atccaattga ttcatgattt gaacacgcac
     2281 acgactcata gcacggctaa gatgttgtac aatgtgaaag cgatccaaca cgattttagc
     2341 acatgggaaa agttgtctag ctaagtcata gtaaggacta aacatatcca tagtaataat
     2401 tttgacgcga catcggacgg ctctatcata tttaagaaag tgatttcgaa tgatagcttg
     2461 tgttcttccc tcaagaacag tgatgatatt gagattgtta aaatcttgcg caatgaagct
     2521 catctttccc tttgtaaaag catactcatc ccaagacata atctcaggaa gacaagaaaa
     2581 atcatgttta aagtgaaaat cattgagctt acgaataaca gttgaagttg agatggaaag
     2641 ctgatgggca atatcagtca tagaaatctt ttcaattaac ttttgagcaa tcttttggtt
     2701 gatgatacga gggatttggt gattcttctt gacgatagaa gtttcagcaa ccatcatttt
     2761 tgaacagtga tagcacttga atcgacgctt tctaaggaga attctagtag gcataccagt
     2821 cgtttcaaga taaggaattt tagaaggttt ttgaaagtca tatttcttca attggtttcc
     2881 gca
//
LOCUS       DAVMJI010000080         2636 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.082, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000080 DAVMJI010000000
VERSION     DAVMJI010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2636
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.082"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            213..1271
                     /locus_tag="VYR58_002042"
     CDS             213..1271
                     /locus_tag="VYR58_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623127.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILIAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            1586..2563
                     /locus_tag="VYR58_002043"
     CDS             1586..2563
                     /locus_tag="VYR58_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623128.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINNPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
BASE COUNT          879 a          343 c          440 g          974 t
ORIGIN      
        1 ttttggtatt atcaagagtg tatagaaaat atttttatag agacgatgat gactaaagtt
       61 tttatcaata atttgggctc cttgtcaact gtagtgggtt gaagaaaagc taacgtctgg
      121 ggaaggggtt aaagctttgc tttatcaaat attgacttac agagttgctc tattgtattg
      181 atgtattctt agtaaataat atggtgtttt gaatgaaaga tgatcagaaa tatttattag
      241 cgggacttta ttcgcttcta gttgcaatat tttattttcc attgattgag tccaagggga
      301 tttttgtaag tatattgatg gcggttttac ttttatattt aatatacttc attgcaacag
      361 tcattcatat tgtgataatt aagtttataa gaaaaaaatc ttttaagtat ttggttctat
      421 atccatttac ttatgatggg agttggagat ttcaacctat aaacttactc tactttccag
      481 aaatggtgag agatgtcatt ccgattaatt tagttcaaga atattgccaa ggacaacctt
      541 acggactgtt aaaaaagatg ctgaaaagaa ttcgattgtc acgagagata tctttactcc
      601 tggctaccat tatcgtctat ttttttacgc atagaattct acctctttca gtatttacgt
      661 tcatattttc ttacatattg ctatttgtac aatcttattt gggtggtaat accgcttgga
      721 ttggaaatag aagattaata atagatgatg aatttgaaaa aatcttgctt tcaaaaagtt
      781 atgtaaaaga aatatcatct gcacgatact cagaatactt gacatgtgaa tacaaaaacc
      841 ttacaccaat catattgata gctatttttg aaaatttgct tgactcctac ttgcttcaga
      901 atcagagtga ggttgactta gatatttttt ataaagtttt acctttgctt tataaagaaa
      961 aatatactat gggattcaat tactttgtaa gtttaaatta tttactatat aaggttggat
     1021 ttttgggaat catttacgat aatgaagcat taagagattt gtcaaaacaa tatttaaaca
     1081 aaaatatttc ggaattacaa gatggttctt tcgagggcgg tatacaagat gctgttgcct
     1141 ctaaacaaat agtagttata aatgaattta tagcttgttt aaattccaga tgcgtgccat
     1201 cccaatatga tagatttttt tataaagata gaccttatat tttttccaga aagagtccta
     1261 ttaaggggtg aaaatttgtt acatttggat taacaagtgt cctagggatt agaaataact
     1321 ctagtatagc tagatatttt tgagtaacta gaaatatcat taggctaccc atatgattgc
     1381 cagaaaagat ggctgatgaa tcttatttat actgttgcag taggcattgt ctaggataaa
     1441 taagctatct tgatggggga aattggaata attttagtag aaacattaaa ggattatgga
     1501 taagtagcgc aggattaggt gatgcaatgt gctaagttgg cttggtgtta gcagtagtat
     1561 tatttaacaa tggaaagtag actaaatgaa aaataaacgt tatttttttg acacaatttt
     1621 aataatttta ctgcttataa gcacgatatt ttgtgtcagc ccagtattta taaaattgga
     1681 catcttagga actccctctc atgccatctt aacctttgta ttggcgatac cgttattcta
     1741 tattttgtct caatgcttac atactttgct attactagtt tcctcaatct tttgtaaatt
     1801 aagaccaatt tatttttatt ttatatttgt gatcattata ggagctagga aatactatcg
     1861 aattctcttt caccaactaa tgggatttag tccaggaata gcagtgtttt ataaggagag
     1921 tcaaacaact aagaatctgt ttaaatttta ctacttcttg tactttacaa cactaatttc
     1981 atactatttt ttctttactt ttgtgtatga caaaccgttg cttttgcctc ttatttcatt
     2041 ttctattatc atagcattag tacaaaaact ttatagaatt gagaatcaac aattatttct
     2101 gttaaaatca aaggtactaa caatactgga atctaagaag aattgtgagt ttaatcttca
     2161 ggattatcat gaaatttgga aattgcaatc aaaatctgag ttgccatgcg tggctttatc
     2221 ttatatcagt ttaatcaagc catatctttc agagagtgtg cgtgaacaaa ttgatttatt
     2281 agaagttaag cgatttaaaa aaataaataa tccaatatca ctttatggta tgttggatgt
     2341 tataaaatta aatctatatt tacggcatta taatgaaaaa aataaatatg aatcaatgtt
     2401 aaagaaaatt ttagaggtaa gaccagactt tgttttaatc gagcagaata ttgatgatag
     2461 tttaaatagc tcgcaaccat tatctttatc tttagccatt tcagaaatcc aacttttgct
     2521 tgaagtgtat atagggatca aacatgtttc aattaggaga taaaactaga ataatatttg
     2581 ccattatagg ggcaagttgc atattagtca gtatgtatct tattccactt attaaa
//
LOCUS       DAVMJI010000081         2160 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.083, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000081 DAVMJI010000000
VERSION     DAVMJI010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2160
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.083"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            244..618
                     /locus_tag="VYR58_002044"
     CDS             244..618
                     /locus_tag="VYR58_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV3623129.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            826..1728
                     /locus_tag="VYR58_002045"
     CDS             826..1728
                     /locus_tag="VYR58_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623130.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            1784..2116
                     /locus_tag="VYR58_002046"
     CDS             1784..2116
                     /locus_tag="VYR58_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV3623131.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
BASE COUNT          720 a          275 c          419 g          746 t
ORIGIN      
        1 gcgttactaa gtcaaaaaaa ataaattttg aaatagtatt agtgagttcg caatcattta
       61 ttgctagtgg tttagaactg ttaagtttca aacaataatt gattttaaac cttaggtaac
      121 ctataaaaac aaataaggta gagaaaggat atcttatcta ggtagctaag tgataaaaac
      181 acagtcgtct atcacttgtt aggaaacgat cctaactatg cttaataaaa aaggagaaaa
      241 taaatggaac tcgtattacc aaataattat gttgctcttg agcaagaaga gatgatgtat
      301 cttgatgggg gattttctat tctgagatgg cctgttgcaa cagccattaa tatagctttt
      361 aatggtgttt taggtggagg agcaatcagt ctagttagaa attatattcg taattatggt
      421 ttgcggcgag ttacaagcgc aattgctgga gcagctgcaa gatatgttgg ggtacgagtt
      481 gcaaatagag tggcaggatt tgcactgtct gctattaatg gatttgcagc ttggatgtca
      541 attggcgatg ctattacaac aatctgggcc aacaatgatg taaataggag agacccaaat
      601 ttaaacgcct tgtggtaact agatatgggt attaaaatgg aaaaaatttt tgttattatt
      661 ttttttgtat gtctatttat atcatccata acttttttag cctatgattt tgttagcgaa
      721 gaaataaaaa agttgattat ttggatgaat gtcgtttttt tgattttaat catagcaatg
      781 ataatttatc caaaattaag aaaatgataa ggacactgta aaattatgat acgtaaacta
      841 atcatttttt tattaatgct ccctcttttt gtcttgtggc tagagttgca tttgttagtg
      901 agtaacttgc aattgaatct agaaattccc cttgattttg tggttagtac gagtcttgct
      961 ttctgtagtt tgattttatc aaaaatagtt ttagacatac tatacgcatt gaaagatttg
     1021 tacaagaaag aagctcttat tacgattttt ccttttattt ttataggcag gaagaaagta
     1081 aatgtgaggt tctcgcccta tttttcattc catcgtaaaa gtttgtcgcc tgatgattta
     1141 agatctagga ttatatggag ttttattctt gaaattgcta ttattctagt atttatttta
     1201 aaaattcctt ttgcaatcat catgcttact acaatatttt tctggactat aatggatatc
     1261 aatcatctcg tttttaataa gacggaattt ctttttaatc aaaataaatg ggaaaaagaa
     1321 gattcgtttg aaagcgattt gacgaaaacg ttaaaggata agatacaaaa atcagagcta
     1381 agttattctg acttaatgtc tcttcagctg tatgatgcga tgaaccaatc caccttttta
     1441 acggatagtg aactttttga ggatattttg aaaaaaatcg aagattctca taacaccctt
     1501 ctgtgtacag gtcttgtcga gttactgctg tatgaaatgt ctattagtaa caataacaac
     1561 tggtccaaca aggttgataa aattaggata cacctcatca gaatcaatca attagatttt
     1621 ttctattata caagttggtt aaggcaaaat tttgatttct gtatgaatag agagtatcat
     1681 aaaatgaaat ctcggaaatt attactgagt aataaaaaga tagtttaagt tcgtcctatt
     1741 tgtaaaacaa atgaaacaat ttcaactaag gaggagaaaa caaatggaac ttgtattacc
     1801 aaataattat gttgtgattg atgaagaaga aatgatgtat cttgatgggg gagcttattt
     1861 aagcaagcgt gcttgtcaag gaatttgcgt agctttagct atgagttcag gaacttttat
     1921 agcattagct ggagctgcag ttttaaccaa aaaactaata aactatatta aggttggagg
     1981 tcttggaggc tggcttattg gtgcagcagc aggaaaaata gcttactgta ttggatatgg
     2041 tgctcttaat agaggttgtg atattagcgg gaacccttat ccttgggatg gatttatatc
     2101 tgcgacagta agatgaataa tgtagataag attcgaaaaa tacatattat cgtatgttgg
//
LOCUS       DAVMJI010000082         2050 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.084, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000082 DAVMJI010000000
VERSION     DAVMJI010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2050
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.084"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(<1..709)
                     /locus_tag="VYR58_002047"
     CDS             complement(<1..709)
                     /locus_tag="VYR58_002047"
                     /inference="COORDINATES: protein motif:HMM:NF012745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV3623132.1"
                     /translation="MKYQLIVSTMNQQDNSLIEKMNIKSDAIIINQSNSFSYHETKLK
                     NSIVKWYEFNERGIGLSRNTGFMRSDADIIQFADDDMIFTDTYYEDVLLEYQKHPEAD
                     VILFSNKCLNEDRMPYQVNNFRRINRFEGVKFGGARITVRREKILHNNITFSLLFGGG
                     AKYGAGEDVTFIQDCIKAGLRVYKSPIIVSTMKQDSSTWFKGYDRKYYKDKGALLAAN
                     FPSISEVGVYIQAFKNRG"
     gene            complement(725..1648)
                     /locus_tag="VYR58_002048"
     CDS             complement(725..1648)
                     /locus_tag="VYR58_002048"
                     /inference="COORDINATES: protein motif:HMM:NF012745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV3623133.1"
                     /translation="MIKRLAILMATYNGEKYIKEQIESILNQDTDFDFTLIIRDDGST
                     DNTKNIIREYVDSGKIIFIEGQNKGAARGFISLLCDNPGYDYYAFSDQDDVWNHNKLQ
                     KGIWSLSKYTGPALYCSNCELVDSELNSIGRNTHRKRPNYTLESILCLASCAQGCTSV
                     FNKELASIIQENDVPDTFIMHDSLITCLCALIGGKIIYDEIPSMKYRMHDDNIFGMVS
                     AKQNVLNVIKDRISEITKKRTISMYDQAECLLKVYKKYIDSNNQDICRIVIDSKVSLK
                     ARLKLIFNKNLQHTTLNKTITKKLEILFGND"
     gene            complement(1687..>2050)
                     /locus_tag="VYR58_002049"
     CDS             complement(1687..>2050)
                     /locus_tag="VYR58_002049"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623134.1"
                     /translation="YLFGAGYISSSPYFETYSIVTGPLGRYYPSDVGLIGLMFRSGII
                     GLIWLISWFYTSLKIIKDNTIRIPAHYDLLMKLVIVFLMFSCINLIITDAPRFPYIAL
                     AMLLFESSYTLSYENSSN"
BASE COUNT          691 a          387 c          236 g          736 t
ORIGIN      
        1 cccccctatt tttgaaagct tgtatatata ctcctacctc acttatagaa gggaaatttg
       61 ctgctaataa agcaccttta tctttataat attttctatc atatccttta aaccatgtag
      121 aagaatcttg tttcattgta gaaacaataa taggtgattt atatacccgt aatcctgcct
      181 tgatacagtc ctgaataaat gttacgtcct ctcctgcacc gtattttgct ccccccccaa
      241 ataaaagaga aaacgttatg ttattatgca atatcttttc tctcctgact gtaattctag
      301 caccaccaaa cttaacacct tcaaacctat ttatacgtct aaaattatta acctgataag
      361 gcattcgatc ttcattaaga catttattcg aaaaaagaat tacatcagct tctggatgtt
      421 tttgatattc taataatacg tcttcataat atgtatctgt aaaaatcata tcgtcatcag
      481 caaattgaat aatatcagca tccgatctca tgaaacctgt gtttcgactt aaaccaatac
      541 ctctttcatt gaattcatac cattttacaa tcgaattttt caatttcgtc tcatggtaag
      601 aaaatgagtt tgattgatta atgataattg catcagattt tatattcatt ttctctatca
      661 gactgttatc ctgttgattc attgttgata caatgagttg atacttcata tctaaactcc
      721 tttattagtc attgccaaat aatatctcta atttttttgt tatggtttta tttaatgtag
      781 tatgctgcaa atttttatta aaaatcagct taagtcttgc ctttagcgat actttagaat
      841 caataacaat tctacatata tcttgattgt tagaatctat atatttttta taaaccttta
      901 gtaaacactc tgcttgatcg tacatactaa tcgttcgctt ttttgttatt tcactaatac
      961 gatcttttat aacatttagt acattttgct tagctgacac cattccaaat atattatcat
     1021 catgcattct atatttcatt gatggaattt cgtcgtaaat tatctttcca cctatcagtg
     1081 cacataaaca agtaatcaaa gaatcatgca taataaaagt atcaggcaca tcattctcct
     1141 gaattatcga agctagctct ttattaaata cagatgtaca tccttgtgca caactagcaa
     1201 gacaaagaat agattcaaga gtatagttcg gtctcttcct atgtgtatta cgacctatac
     1261 tatttaactc tgaatcaact aattcacaat tagaacaata aagtgctggc ccagtatatt
     1321 tggaaagact ccatatacct ttctgtaatt tattatgatt ccaaacatca tcttgatccg
     1381 agaaagcata gtaatcatat ccaggattat cacataacaa agaaataaat cctcttgccg
     1441 cccctttatt ctggccttct ataaaaataa ttttcccact atcaacatat tctctaatta
     1501 tatttttagt attatctgtt gaaccgtcat ctctaataat tagagtaaaa tcaaaatctg
     1561 tatcttggtt gagaatactt tcaatttgct cttttatata tttttcgcca ttatatgtgg
     1621 ccataagtat tgctaatctc ttaatcattt cccctcatcc tttaaaataa ctatctgaaa
     1681 tacattctaa ttagaactgt tttcataact caaggtataa cttgattcaa aaagtaacat
     1741 agctaatgca atatatggga atctaggtgc atcagtgatt atcaaattaa tacaagaaaa
     1801 catcaaaaaa actataacta gcttcattaa taagtcataa tgagctggaa ttctaatcgt
     1861 attatcttta attatcttca agcttgtata aaaccaactt attaaccaaa ttagcccgat
     1921 aatcccactt ctaaacataa gtccaatcaa acctacatcg cttggataat aacgtcctaa
     1981 tggaccggta acaatagaat aagtttcaaa atatggacta gaagaaatat atcccgctcc
     2041 aaataagtaa
//
LOCUS       DAVMJI010000083         1888 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.085, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000083 DAVMJI010000000
VERSION     DAVMJI010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1888
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.085"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            550..>1888
                     /locus_tag="VYR58_002050"
     CDS             join(550..991,991..>1888)
                     /locus_tag="VYR58_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSpn4 family transposase"
                     /protein_id="HEV3623135.1"
                     /translation="MKLSYEDKVQIYELRKQGYSLEKISNKFEINNSNLRYMIKLIDR
                     YGIEFIKKGKNRYYSPELKQEMIDKVLHENWSQDRVSLKYALPNRGMLPNWLAQYKKN
                     GYTIVEKTRERVPKMGRKRKKTWEEMTELERLQEENERLRTEVAYFKKVKRAGRQGRS
                     PRARKAEIVREMASGGFQLDLLLETARLARSTYYYQLKGLGGLDKDKDLKAEIQAIFT
                     EHKGNYGYRRVTLELRNRGFVVNHKKVQRLMKVLGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPASSQKLYLSPVLDGFNSEIIAYNLSTSPNLEQ
                     GKAMLNQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKTFQSLNQLEQAIVDYIDYYNNKRIKIKLKGLSPVQYRT"
BASE COUNT          664 a          331 c          373 g          520 t
ORIGIN      
        1 agtctggaaa cgataaactc cgtgtctgtt agaaaattct cacacacgtc ttgtgccagt
       61 tgcccttcac agggaaatac tctcagtccc tacttacaca ggcacgctaa tcaagacgga
      121 gtgaattcaa ttttcaaaga acaggtagct ttattataga taagagtagt tgaaattttt
      181 atcacatctt tgaggttatt ggaataatca ggtaagtgct aatttctagc tcttctcaca
      241 acaccgtact taccttttat gttttatgaa cagtagctat catttacatt ttcaaactac
      301 cattctatca gactaaaagt caaaatagac gcttctactt cgagatatac tcatttaatg
      361 gttcagcaat tcgctctact tctgttacag aaatttcatc actttgactt ctcatgattt
      421 gttattagtt cactttgagg gcttgctcat gaagccaaac agcgtaagtc gtaaaagaaa
      481 aaagcagtac aagatgaact gcaccccaaa agttagacag aaaaaatcta ctttttgggg
      541 tgttttatta tgaaattgag ttatgaggat aaagttcaga tctatgaact aagaaagcaa
      601 ggatatagct tagagaagat ttcaaataaa tttgagataa acaattctaa tcttaggtac
      661 atgattaaat tgattgatcg ttacggaata gagttcatca aaaaagggaa aaatcgatac
      721 tattctccag aactaaaaca agaaatgatt gataaagttt tacatgaaaa ctggtctcaa
      781 gatagagttt ctctcaaata tgctctccca aatcgtggta tgcttccaaa ttggctggcg
      841 caatacaaga aaaacgggta tactattgtt gagaaaacaa gagagagagt acctaaaatg
      901 ggacgtaaac gtaagaaaac ttgggaagaa atgacagaac tagagcgact tcaagaggag
      961 aatgaacgct tacgtaccga ggtggcttac ttaaaaaagt taaaagagct ggaagacagg
     1021 gacgaagccc tagagcgaga aaggcagaga tagttagaga aatggcttca ggaggatttc
     1081 aattagattt acttcttgaa acagcacgtt tagctcgctc gacttactac tatcagttga
     1141 agggactagg tgggcttgac aaagataaag atcttaaagc tgaaattcaa gctattttta
     1201 ctgagcacaa aggaaattat ggctatcgta gagttactct tgaactaaga aatcgtggtt
     1261 ttgtggtgaa tcataagaaa gttcaacgtc tgatgaaagt tcttggttta acagctcgaa
     1321 ttcgtcggaa acgaaagtat tcctcctacc aaggagagat tggcaagaaa gcagagaatc
     1381 tcattcaacg ccagttcgaa gcatcgagac caatggaaaa gtgctatacg gatgtgacag
     1441 agtttgccat tccagcaagc agtcaaaagc tctatttatc gccagtttta gatggcttta
     1501 acagcgaaat tatcgcctat aatctttcaa cttcaccaaa cttagaacaa gggaaagcta
     1561 tgttaaacca ggcctttaca gagaaacatt atgagaatac cattctccat agcgatcaag
     1621 gctggcaata ccaacacgat tcttatcatc ggttcctaga gagtaaggga attcaagcat
     1681 ccatgtcacg caagggaaac agcccagaca atggcatgat ggagtccttc tttggcattt
     1741 tgaaatccga aatgttttat ggttatgaga agacatttca gtcgcttaat caattggaac
     1801 aagctattgt agactatatt gattattaca acaacaaacg aattaagata aaactaaaag
     1861 gacttagtcc tgtgcaatac agaactaa
//
LOCUS       DAVMJI010000084         1888 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.086, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000084 DAVMJI010000000
VERSION     DAVMJI010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1888
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.086"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            28..765
                     /locus_tag="VYR58_002051"
     CDS             28..765
                     /locus_tag="VYR58_002051"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623136.1"
                     /translation="MIDEYAKEYSISNYNDIPNVLSNLIDDKNNKIISLAQELKKHQD
                     IIIYNALNENIRQKKKSLQQPQKTITALKEKLEIVDEEIKKINESYNFVQLINSNESI
                     IQQYFNYLNPNVSSYRNLYFNINDDDNTLDIEIKNSDGTTNAANVLSSGQLNVLAIAI
                     FIAKNISQNSTVIDFIGIDDPIQNMDDINQFSMIDVLSQLKKQLIFTTHDVKYVNLFL
                     KKNELRLDDISVYYLDAENDKYENILI"
     gene            1136..1492
                     /locus_tag="VYR58_002052"
     CDS             1136..1492
                     /locus_tag="VYR58_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623137.1"
                     /translation="MKRNIRSVRKQFRLTETEEKQILDLMREKGEDNFSDFLRKSLLL
                     SDGQKQMEKWFNLWKKQKLEQICRDVHEVLIISKSDHQVTQEHVSILLTCIQELIKEV
                     ENTSPLSEDFRNKYMR"
     gene            1497..1862
                     /gene="mobC"
                     /locus_tag="VYR58_002053"
     CDS             1497..1862
                     /gene="mobC"
                     /locus_tag="VYR58_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEV3623138.1"
                     /translation="MEHRYRTNLKKVFLSDLELVKLNENISKSNCLSFSEYARRTLLN
                     PGMNFITIDTNSYQDLIFELKRIGNNINQIARSINYSNLITEFELNELRKGIEELIVE
                     VEKDFLIQSEKLRKFYGHH"
BASE COUNT          725 a          236 c          311 g          616 t
ORIGIN      
        1 tttaatttgc tgaacaatgt gagtgaaatg attgatgaat atgccaagga atattctatt
       61 agcaattata atgatattcc gaatgttctg tcaaatttaa ttgatgacaa aaataataaa
      121 attatttcac tagctcaaga gttaaaaaaa catcaagata ttattatata taacgcttta
      181 aatgaaaata tacgtcaaaa aaagaaatct ttgcaacaac ctcaaaaaac tatcacagca
      241 ttgaaagaaa aattggaaat tgtagatgaa gaaataaaga agattaatga atcatataac
      301 tttgttcagt taattaacag caatgaatca attatccaac aatattttaa ttaccttaat
      361 ccgaatgtat caagttatag aaatttatat ttcaatataa atgatgatga taatacgtta
      421 gatattgaaa taaaaaatag tgatggaact actaacgctg ctaatgtttt aagttctgga
      481 caactgaacg tattagcaat cgctattttt attgcgaaga atattagtca gaatagcaca
      541 gtgattgatt ttattggtat agatgatcct attcaaaata tggatgacat taatcagttc
      601 tctatgattg atgttctcag tcaattaaag aagcaactca ttttcactac acatgatgta
      661 aaatatgtaa atctatttct gaaaaaaaat gaacttcgct tagacgatat ttctgtatat
      721 tatttggatg ctgaaaacga taaatatgag aatattttaa tttgagatta gactcaatga
      781 tggattatat gtatttttag aattgagagt caagaattat tgaccctctt ttttatcatc
      841 tcatttccct gtgataaaat ttccaacttt cctttgctat acttttctca acttgtaaaa
      901 atctatgtta gattttctat gggggtttgg gggaggagcc accaagttat catatcgtta
      961 gctttcaaaa ctagaaggtt ttgatcagct ggcgatatga tttttaggat attgtggaca
     1021 caatatctga gctcgcaaag ccttacaaaa tgttgaagct attttgaaaa atgtactgac
     1081 agtgtctgta agcttacatt gtcagtacag gtatcaatga aggaggaaaa gttatatgaa
     1141 aagaaatata cgtagtgttc ggaaacaatt tcgcttaaca gaaacggagg aaaaacaaat
     1201 actagattta atgagagaga aaggagagga taatttttct gattttctcc gtaaaagctt
     1261 actattgtcc gatggacaaa aacagatgga aaaatggttc aacctttgga aaaaacaaaa
     1321 gttggaacaa atttgtcgcg atgttcatga agttttaatc atttctaaaa gcgatcatca
     1381 ggttactcaa gaacatgttt ctattttgtt aacttgtatt caggaattaa ttaaagaggt
     1441 agaaaatacc agtcctctta gtgaagattt tcgtaacaaa tacatgaggt agtagagtgg
     1501 agcaccgata tagaacaaat ttaaaaaaag tctttttatc tgacctagaa ttagtcaaat
     1561 tgaatgaaaa tatctcaaaa agtaactgct tatcattctc agaatatgct agacgaactc
     1621 tactaaatcc tggtatgaat tttatcacca ttgatacaaa tagttatcaa gatttgattt
     1681 ttgaattaaa acgaatcgga aataatatta atcaaatagc cagaagcata aattattcga
     1741 atttaataac ggaatttgaa ttaaatgagt tgagaaaagg tatagaagaa ttaatagtag
     1801 aagtggagaa agattttctt attcaatctg aaaaattgag gaaattttat ggtcatcact
     1861 aaacactttg cgattcatgg aaaaaatt
//
LOCUS       DAVMJI010000085         1863 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.087, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000085 DAVMJI010000000
VERSION     DAVMJI010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.087"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..343
                     /locus_tag="VYR58_002054"
     CDS             <1..343
                     /locus_tag="VYR58_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623139.1"
                     /translation="SGIIGVFISEYYQRKTLVKKMKRDFVIELFANRYMLKESYLGDG
                     NELNRSLGKIPIIFSDNEEVINCYDNLLSVTNDKNFLKLIKSVCKDKNVNIDISNWDD
                     EMIMKTLSIGK"
     gene            679..1560
                     /locus_tag="VYR58_002055"
     CDS             679..1560
                     /locus_tag="VYR58_002055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV3623140.1"
                     /translation="METVVLQEILNIQNPEDFYVKLNKIDQFGIDTKSLYINDQPKLL
                     EQMGYLYDTLRKTNKPHFNYVMDRPYTIHLIPYDEANKLWLFVGAYSQSGTYQQTYED
                     RVTTYYKLNLAPEHSKLKGRLIVKFERPDGSQHVRIGLESATAQGFKLHSILEREISS
                     VEFQDYRNVRLTYQELKSIIKNQNPTWKTALSHLNAIYLQTDTKTGKQYVGSAYGKQK
                     LWGRWTEYVETYHGVNKALKELFKKEGASYFEDYFTYMLLEVLPSDNKEIGNTVISRE
                     SWWKIALQTREFGYNCN"
BASE COUNT          694 a          247 c          340 g          582 t
ORIGIN      
        1 atcaggaatc attggagtgt tcatttcaga atattatcaa agaaaaacct tagttaaaaa
       61 aatgaaaaga gattttgtga tagaactctt tgctaataga tatatgttga aagaaagcta
      121 tttgggtgat gggaatgaat taaatagatc acttggaaaa atacccatta ttttttctga
      181 taatgaagaa gtaattaact gttatgataa tttgctttca gtaacaaatg ataagaattt
      241 tttaaagtta ataaaatctg tatgtaaaga taaaaatgta aatattgata tttctaattg
      301 ggatgatgag atgattatga agacgttatc gattggtaaa tgataatctt ttatttaaag
      361 ttaataaatt ttgatataat agatttataa gaggcaaagg aattataaaa tgtgaagata
      421 atcatagctt accctgtttt tatgatcaga ttggtttttt agaaatataa aaacaatttt
      481 ttcattgcaa agtgaaagcg aggtattgag atgagctaaa atatagaaat caaaatccaa
      541 caagcctttc gtaatttcgt aatattgtgg aaagttttga ttaacgatat gtaactgggg
      601 gattgttgaa aaaagatgct attttaatcg caagatttag aaagtaagta gttcactaca
      661 aattgaaagg aatttaaaat ggaaacagta gtattgcaag aaatcttaaa cattcaaaac
      721 ccagaagatt tttacgtaaa attgaataaa atcgatcaat ttggaattga tacgaaaagc
      781 ctttatatta atgaccaacc aaaattattg gaacaaatgg ggtatctcta tgacactttg
      841 cgtaagacta ataaacctca ttttaactat gtaatggacc gcccttatac cattcaccta
      901 atcccatatg acgaagctaa taaattgtgg ctctttgtag gggcttactc tcaaagcggt
      961 acttaccaac aaacgtatga agaccgtgta acgacttatt acaagttgaa tttagctcct
     1021 gagcacagta agttgaaagg ccgtttaatt gttaaatttg agcgtcctga cggttcacaa
     1081 catgtacgaa ttggtttgga atctgctaca gctcaaggat ttaagctgca ctctatttta
     1141 gagcgtgaaa tctcaagtgt tgaatttcaa gattatcgaa acgttcgcct aacttatcaa
     1201 gagttgaaaa gcattattaa aaatcaaaac cctacatgga aaacagcttt gtctcatttg
     1261 aatgctattt accttcaaac agatacaaag acaggaaagc aatatgtagg ttctgcttac
     1321 gggaaacaga agctttgggg gcgttggaca gagtatgttg aaacctacca tggtgtaaat
     1381 aaggccttga aagaactctt taaaaaagag ggtgcaagtt attttgaaga ttacttcact
     1441 tatatgcttc tagaagttct tccaagcgac aataaagaaa ttggaaatac agtaatcagt
     1501 cgcgaatctt ggtggaaaat tgctcttcaa actcgtgaat ttggatataa ctgtaattaa
     1561 atgcgaatac ttgctcaaca attatgtaat atactaatcg ataaaaaacc aacaaaataa
     1621 agagcctgaa acaaaatagt tctcaatcac ataaaagcta gagttccgcc aactggaaag
     1681 ctctagcttt tttataactg aggaccattt tgtcttagac actttgtaag tataatgaga
     1741 atattgttta ttgaggtgtt ttaaccatct agtctagagt tagactaacg ctagatagtg
     1801 tagaaaggaa gagggagtta aactattgtt ttacgaatat ataatgtgta tgaaaggata
     1861 cag
//
LOCUS       DAVMJI010000086         1852 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.088, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000086 DAVMJI010000000
VERSION     DAVMJI010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.088"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            21..1022
                     /locus_tag="VYR58_002056"
     CDS             21..1022
                     /locus_tag="VYR58_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV3623141.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1624..1704
                     /locus_tag="VYR58_002057"
                     /pseudo
     CDS             1624..1704
                     /locus_tag="VYR58_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            1693..>1852
                     /locus_tag="VYR58_002058"
     CDS             1693..>1852
                     /locus_tag="VYR58_002058"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623142.1"
                     /translation="MDRTDEVSSKYCFEVVDRTDEVSLKHCFEVADRTDEVSLKHCFE
                     VADRTDEVS"
BASE COUNT          616 a          249 c          382 g          605 t
ORIGIN      
        1 gtttgtaata gaggactgaa atgaaaaata taaatgggaa aaaggtaact atttatgata
       61 ttgcacgttt atcaggtttt tctccaaaaa cagtttcacg agttattaat ggtggagtaa
      121 atgttaaaga agaaacttat caagcgattc aaaaagttat agaggaattg tcgtatattc
      181 caaatgcgta tgcaaaaaat ttaactaaaa aagaagctat aaatatattg atttctgtaa
      241 aaaaaatcga ctcttttcct ttaatttggt ttcatacgct gttagataaa gtgttacgga
      301 cgtgtaaaga atttggtgtt aatgctatag ttgagtactt tggagaggag gatacaatta
      361 gtaattcaat tatatcaagc acaggtagcc tagtagatgg tgttattgtt ttttatgaaa
      421 gtgtagatga tatcagaatt cagtatttaa agaagaacca tatgcctttt cttgttttcg
      481 gtgaatctca aacgtctgga gtagtctatg tatctaataa taattttcaa gctacttatg
      541 atatgatgaa agctgtaact gaagaaaaat ttaaaaatat gtggttgctt atgggaggag
      601 aatctcatgt taataaggat cgtgaaagag gtgtgcgttc ttttctgaat gataaaaatt
      661 actttatgga tttaaaagtc atttatggct tatctacaat tgattcagtt tattcttatg
      721 caatgcagca cttgactacc caaaattatc cggacattat ttttgtttca ggagatgaaa
      781 aggttcaggg cttgattcgt gcgtgctatg agaaaggaat tcttattcca gatgatattt
      841 ctattattgg atttgataat attcctattt ctcagtatta tactccagct ttgtctacaa
      901 ttgctcccaa ttatgttaaa ttggctaaag aaatgataga aggtgtttta gcaattatta
      961 aaggggaaag tgtcacatct gttgaagttt ctcctaaatt tgttaggaga cagagtttct
     1021 agtattgttt aattcttgaa aatcctagtg gaaaagatgg agtgttctaa aataagttct
     1081 gtttagcctc cattcagttt ctattgagtt ggatccaatt tctaacaagt gggacatgtt
     1141 catgttcgat ctaaggaaga catggtcaca ttcgaatgat attttcaaaa aaatcgtaaa
     1201 aaagtcttga caaagaaaaa acaaagtatt aaaataagtt caacaaatca gaaaagtaac
     1261 tatttttgat cttcagggag cctgtggtga ttgtgaatag gtggttggaa gtagtgaaag
     1321 tgggctgatt ttgaaaatga atttgaaaca atgaaaattc ggtgcgcaca ccttacagtg
     1381 cagcttgttg ttaaacaagg cagagatgta aagggatagt ccctttataa ttgaggtggc
     1441 accgcgttac caacgccctc acacggaagt atattctgtg tgtgggcttt tttctatccg
     1501 tcgtttggtt tatcttttat tagggcctta agtcgctttg atgaacttga gttctatcta
     1561 cagctccttg cctactacta aaagcaaaca aaaaggctgg actaatacga aaaaagctag
     1621 taatactcaa tgaaaatcaa agagtaaact aggaaactag ccgcaggttg ctcaaaacac
     1681 tgttttgagg ttgtggatag aactgacgaa gtcagctcaa aatactgttt tgaggttgtg
     1741 gatagaactg acgaagtcag cttaaaacac tgttttgagg ttgcagatag aactgacgaa
     1801 gtcagcttaa aacactgttt tgaggttgca gatagaactg acgaagtcag ct
//
LOCUS       DAVMJI010000087         1769 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.089, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000087 DAVMJI010000000
VERSION     DAVMJI010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1769
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.089"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            365..841
                     /locus_tag="VYR58_002059"
     CDS             365..841
                     /locus_tag="VYR58_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV3623143.1"
                     /translation="MIGKNIKSLRKTHDLTQDDFSRIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            841..1602
                     /locus_tag="VYR58_002060"
     CDS             841..1602
                     /locus_tag="VYR58_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV3623144.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFESIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
BASE COUNT          644 a          239 c          346 g          540 t
ORIGIN      
        1 agtaaaaaca acactttatt gaggtattgg atacgctttg ctaatagcct aataatcaca
       61 tgtggagtgt tgctacaacg aaaaaggtga taatccttaa tttcaagcta ttttataagc
      121 attttgtctt tgtagataaa ggcaattttg acaataaaaa tcctaaaagg tgaatcgtta
      181 tagatgtatt tgtagatatt gtttgcgcat cgaaaaaatt aatacaagaa taaatattta
      241 tagctcttta ggtgactttt atagaagtaa agtttaggat agaaaaacaa gaaataacgc
      301 accatttttg gtgcgttatg cttttttatg ctataatgga tttataaaaa taaaggagtt
      361 tgctatgatt ggaaagaaca taaaatcctt acgtaaaaca catgacttaa cacaagacga
      421 cttttcccga attgtaggaa tttctcgaaa tagcttgagc cggtatgaaa atggaactag
      481 ttcagtctct acggaactaa tagacatcat ttgtcagaag tttaatgtat cttatgtcga
      541 tattgtagga gaagataaaa tgctcaatcc tgttgaagat tatgaattga ctttgaaaat
      601 tgaaattgtg aaagaaagag gtgctaatct attatctcga ctctatcgtt atcaagatag
      661 tcagggaatt agcattgatg atgaatctaa tccttggatt ttaatgagtg atgatctatc
      721 tgacttgatt catacgaata tctatttagt agaaactttt gatgaaatag agagatatag
      781 tggctatttg gatggaattg aacgtatgtt agagatatct gaaaagcgga tggtagctta
      841 atggaaatcc aagattatac tgatagtgaa ttcaaacatg ctttagcaag gaatcttcgt
      901 tcactgacaa gaggaaaaaa gtccagtaag caacctatag cgattttgct tggagggcaa
      961 agtggtgccg gtaagactac aattcatcgt attaaacaga aagaatttca aggaaatatt
     1021 gttatcatag atggtgatag ttttcgttct cagcatccac actatttaga actgcagcaa
     1081 gaatatggca aagacagtgt agaatatacc aaagattttg caggaaaaat ggtagagtct
     1141 ttagtaacaa aattgagtag tttgagatac aatcttttga tcgagggaac tttacgaaca
     1201 gttgatgttc caaagaaaac agcacaactc ttgaaaaata agggatatga agtacaattg
     1261 gccttaattg cgacaaagcc tgaattgtcg tatctaagta ctcttatccg ttatgaagaa
     1321 ctgtacatta tcaatccaaa tcaagcacgc gcaactccaa aagaacatca tgatttcatt
     1381 gtaaatcatc tagttgataa tacacgacaa ttggaagaac tggctatctt tgaaagcatt
     1441 caaatttacc aacgagatag aagttgtgta tatgattcaa aagaaaatac aacttcagca
     1501 gcagatgttc ttcaagagtt actctttggg gagtggagtc aggtagagaa ggagatgttg
     1561 caggtggggg aaaagagact taatgaatta cttgaaaaat aaacaattga tatttttagg
     1621 agaatagaaa tgagagggtt taataacaag ataaagtctg tttatcaaga actaacaaat
     1681 tccaaagaga aattcggtag ctttcacaag actttaattc atttgcatac acctgtttct
     1741 tatgattaca agctattttc taattggac
//
LOCUS       DAVMJI010000088         1751 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.090, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000088 DAVMJI010000000
VERSION     DAVMJI010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1751
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.090"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(<1..729)
                     /locus_tag="VYR58_002061"
     CDS             complement(<1..729)
                     /locus_tag="VYR58_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV3623145.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNVLLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEM"
     gene            complement(722..1450)
                     /locus_tag="VYR58_002062"
     CDS             complement(722..1450)
                     /locus_tag="VYR58_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3623146.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(1484..1654)
                     /locus_tag="VYR58_002063"
     CDS             complement(1484..1654)
                     /locus_tag="VYR58_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623147.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT          648 a          297 c          187 g          619 t
ORIGIN      
        1 catctcaaaa cttctttcgt tcaatttacg aattaatata taaaaaagta cgatgattat
       61 tatattagat agtaaaatca tataaaattg actttcagtc actctaaaag catgagaaag
      121 ataagtaaat ggtaagtaaa tcttaaaatt ataatcgttg tagtatatgc taattgttaa
      181 aatcatcatt ataataccaa ttggtattat tccagaaatt ttccttataa gtactaaagt
      241 tagaaaatat aataacatta tcatcaacga ggaaattaat tgaatggtaa atgtttttaa
      301 aaagaaaatc aaaccaatct ctaaactgtt atcaatagcc ttcccaataa cgtataagct
      361 aatataatca gacaaccaaa aagtaaatgt gtaaaccact gtaatgagta atttagaatt
      421 tattgtgtac ttgtttctaa atggcaatga aattacggtt aaccatgcat catttttaaa
      481 ttctactgca aacacttcgt aaattattaa agatagaact aaataaaata gttcagaaaa
      541 ataaaatatt gtttgttctt taaaaattaa ctgccaatta gataaagcaa gttcattttg
      601 atgcaccaat aaataacctc gatacctaaa agttaagtct atatataaca aaacattcag
      661 aattattgga aaaataagaa caaaccataa gatgcttttt ttctgcttta gaaactctaa
      721 tttaatcata ttcacctcca gctaaacaag ctaagtaggc ttcttccaga tttcgacaat
      781 tatacttttg taaaaggtag tggcaagaac caaaaaattc aactttccca taatttataa
      841 ttataatatc agatatcact ttatccagtt cactaagaat atgacttgat attaaaaatg
      901 taataccttt tttctcctgt agaaaacgga ttaaacttct aatttcaatt acaccctgtg
      961 gatcaagtcc attgattggt tcatcccaaa ttaatatttc tggactacct aacaatgatg
     1021 cagctatact tagacgttgt ttcatgccca ttgaaaaatt tttcactttt ttctttttaa
     1081 catcttttaa tcctaccatt gatagatatt cattaagtct ttcagtatct aaactaagcc
     1141 ctttcatatt tgctattaac ttcaaatttt tataagcatc aagatgacca taaaatgaag
     1201 gtcccaaaac taatcctatc ctagataata tattttcgga attctgttct acggtttgat
     1261 taaaaatagt tattttccca gaatctggtt ttaaaatccc tagaatcatt ttgataattg
     1321 tagtttttcc agccccattt ggtccaacaa aaccatatac ttttccctta tttaaataaa
     1381 atgaagtgtt atgaataact tcaatatctt taaagctttt tgttagattt ataatttcaa
     1441 ctatagccat ctctactcct tagtttacag caaaaaatta tgcttaattc ttattgtttt
     1501 tgtaaacaat cagcgaaccc aatactattc cattcaacaa gcctaaagaa ataccatatt
     1561 caactggaaa atctaaaaaa attgcaaaca ctattccaat catcacccct agtgaggctg
     1621 ttgttaaaat tacatattca ttttctttct tcattttctt tacacctcat ttcctttttg
     1681 tatataagct gtagtactct ccaccaagat ccattaagta cttatgattt cctgactcaa
     1741 caatcttacc a
//
LOCUS       DAVMJI010000089         1730 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.091, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000089 DAVMJI010000000
VERSION     DAVMJI010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1730
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.091"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..1721
                     /locus_tag="VYR58_002064"
     CDS             <1..1721
                     /locus_tag="VYR58_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV3623148.1"
                     /translation="GMRNYLDFPSYKELVKMYNDNFLSNDTLYEFRHDRQEVNQRKIH
                     SHHIIQSFSPDDHLTPEQINRIGYETVKELTGGRFRFIVATHVDKDHIHNHIILNSID
                     QNSDKKFMWDYKAEHNLRMVSDRLSKIAGAKIIENRYSHRQYEVYRKTNYKYEIKQRV
                     YFLIENSKNFEDLKKKARALNLKIDFRHKHATFFMTDSTMKQVVRDNKLNRKQPYNET
                     YFKKKFVQREIINILEFLLPKMKNMNELIQQAELFGLKIIPKEKHVLFEFNGIKLSEQ
                     GLGKTNRYSVSYFQDYFNNKNETVVLDSKNLVELYNEEKLIKEKELPTEEVVWKSYQD
                     FKRNRNAVHEFEVELNLNQIEEVVDDGMYIKVQFGIRQEGLIFVPNIQINMEEEKVKV
                     FLRETSSYYVYHKDSAEKNRFMKGKTLIRQFNLQYEPQYMYRRTPLSKIKEKIEQLDF
                     LISAENIPNDFEDITNDFIAQISYLENKIEQVQNKIDDLTNLEEVLLNNTTNSSINLE
                     NSIQGKSSVDTIEKDLYIYKGKIETLKEQHREAINLFEMFNKTIKKYKKKQNMKSIEE
                     NEIHLE"
BASE COUNT          720 a          206 c          287 g          517 t
ORIGIN      
        1 ttggtatgag aaattattta gattttccta gttataaaga actagtgaag atgtacaatg
       61 ataatttttt aagtaatgat actctttatg aatttcgtca tgatagacaa gaagtaaatc
      121 aacgaaaaat tcattctcat cacatcattc agtccttttc tccagatgac catctcactc
      181 ctgaacaaat caatcgaatt ggttatgaga cagttaaaga gttgacagga ggaagatttc
      241 gttttattgt agcaactcat gtcgataaag atcatatcca caatcacatc atcctaaatt
      301 caattgatca gaattctgat aaaaagttta tgtgggatta taaggcagaa cataatctac
      361 gaatggtttc tgatcgtctt tcaaaaattg caggggcaaa aattatagaa aatcgttatt
      421 cgcatcgtca gtatgaagtt tatcgcaaaa caaattacaa atatgaaata aaacaacgag
      481 tatattttct aatcgagaac tcgaaaaatt ttgaagatct taagaaaaaa gctagagctt
      541 taaatttaaa aattgatttt agacacaagc atgccacctt ttttatgacg gattcaacta
      601 tgaaacaggt ggtgcgtgat aataaattga atagaaaaca accttataat gaaacatatt
      661 ttaagaaaaa gtttgttcaa agggaaatca taaacatctt agaatttcta cttccaaaaa
      721 tgaagaatat gaatgaattg attcaacaag cagaattgtt tggtttaaaa ataattccga
      781 aagaaaaaca tgttctattt gaatttaatg gtattaagct ttcagaacag ggattgggaa
      841 aaacaaatcg gtatagtgtt agttattttc aagactattt taataacaaa aatgaaactg
      901 ttgtcttaga tagtaaaaat ttagttgaac tttacaatga agaaaagcta attaaagaaa
      961 aagagttgcc gacagaagag gtggtatgga aatcctatca agatttcaag agaaatagga
     1021 atgcagttca tgagtttgag gtagagttga atcttaatca aatagaagaa gtagtagacg
     1081 atggaatgta cattaaggta cagtttggca tccgacaaga gggacttatt tttgtaccaa
     1141 atattcaaat caatatggaa gaagaaaaag ttaaagtatt tcttagagaa actagttctt
     1201 actatgtata ccataaagat tcagcagaaa aaaatcgctt tatgaaaggt aaaactttga
     1261 ttaggcaatt taatcttcag tatgaaccac agtatatgta tagaagaaca cctcttagca
     1321 aaattaaaga aaaaatagaa caattagatt ttcttatatc tgcggaaaat attccgaatg
     1381 attttgaaga tataacaaat gatttcattg cccaaatatc atatctagag aataagattg
     1441 aacaagtcca aaataaaatt gatgatttaa ctaatttaga ggaagtattg ttgaataata
     1501 cgacaaatag ttctatcaat ttagaaaata gtattcaagg taaaagttca gtagatacaa
     1561 tagagaagga tttatacata tataaaggaa agattgaaac actgaaggaa caacatagag
     1621 aagcaataaa tttatttgaa atgtttaata aaacaataaa gaaatataag aaaaaacaaa
     1681 atatgaaatc tattgaggaa aatgagatac atttagagta aacagtttcc
//
LOCUS       DAVMJI010000090         1578 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.092, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000090 DAVMJI010000000
VERSION     DAVMJI010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1578
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.092"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..673
                     /locus_tag="VYR58_002065"
     CDS             <1..673
                     /locus_tag="VYR58_002065"
                     /inference="COORDINATES: protein motif:HMM:NF024584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SPASM domain-containing protein"
                     /protein_id="HEV3623149.1"
                     /translation="DLTISFDSSDNIILSSIRGKISKETIDRSIVMIRELAKLAEQTG
                     CIERIIIQKIQLNNNDEDTVTVKNIASESPKTQFVHKKFIRFPKVRNYSKYGTLEKLE
                     KGKSVFLYHLIGAKTPFKCLKPWIKNELAVNSDGNYVPCCLTLNSSINLGNIENETIS
                     EVFDSEEHYLLRESVFLNSLKNNSTCLTCPINEPNLEIPNELAESQSIEKLKKYIISD
                     WRFFP"
     gene            670..>1578
                     /locus_tag="VYR58_002066"
     CDS             670..>1578
                     /locus_tag="VYR58_002066"
                     /inference="COORDINATES: protein motif:HMM:NF015983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEV3623150.1"
                     /translation="MKKIKYDNPIGAQIELTGRCNLKCHHCYNSSGDFGRFDIKDDAW
                     LSFFEKLNESYSFPTVNITGGEPMLRKDLLLKVLNIFSNKNPYTRIRIMTNGYYLDKT
                     FLEYLSLINNPIEFQISLDGADKAEHQAVRIVRNSWEKAINSCIMVVNSGYKLQIAST
                     ITTSNYDKIERLFKLAVLVGATSLGIGSALPLGRGIRDVKGLILPSQLREEVSMKLKA
                     LKQDYESFISVNLTSSLSEVYSKYASLEQDWLIIDHRGNVKIDTRLPYIVGNISSKSI
                     EELWLLVQEKYNDSIVKENITSALDNN"
BASE COUNT          566 a          208 c          293 g          511 t
ORIGIN      
        1 agatttaaca atctcatttg attctagtga taatattatt ctatcatcta ttagaggaaa
       61 aatttctaag gaaacaattg atagaagtat agtgatgata cgggaacttg ctaagttagc
      121 tgaacaaaca gggtgtatcg agaggataat aattcaaaag attcaattaa acaataacga
      181 cgaggataca gtaacggtaa aaaatatagc atctgagagt ccaaaaactc agtttgtaca
      241 taaaaaattt ataaggtttc cgaaggtaag aaattattct aaatatggta ctttagaaaa
      301 attagaaaaa ggtaagagtg tttttcttta ccatttaatt ggagctaaga ccccttttaa
      361 atgtttaaag ccttggatta aaaatgaact agccgtaaat tccgatggga attatgttcc
      421 ctgttgcctg actctgaatt cttcgattaa tttgggaaat attgagaacg aaacaatttc
      481 ggaggtattt gacagtgagg agcactattt actacgggag tcagtatttc taaattctct
      541 taaaaataat tcaacctgtc taacttgtcc gataaatgag ccaaacttag aaattccaaa
      601 tgagttggct gagtcccagt caattgagaa attaaaaaag tatattattt ccgattggag
      661 gtttttcccg tgaaaaaaat aaaatatgat aatccgatag gtgcccagat agaattaact
      721 ggacgttgta atttaaaatg ccatcattgt tataattctt caggagattt tgggagattt
      781 gatattaaag acgatgcatg gttatcattt tttgaaaaac tcaacgaaag ttactctttt
      841 ccaacagtta atattactgg tggagagcct atgctgagaa aagatttatt gttaaaagtc
      901 ttaaatattt tttcaaataa aaatccttat acacgcatta gaattatgac gaatggctac
      961 tatttggata agactttttt ggaatacctt tcacttatta ataatccaat tgaatttcaa
     1021 atatctttag acggggcaga taaagcagaa catcaggcag ttaggatagt gagaaattct
     1081 tgggaaaaag caataaattc ctgtattatg gtagtaaatt caggatataa gttgcaaata
     1141 gcgagcacta ttacaacatc caattatgat aagatagaaa gactgtttaa acttgcagta
     1201 cttgtgggag cgacttcatt aggtattggt tcagctttgc ctttaggacg agggattcgt
     1261 gatgtgaagg gcttaatttt gccgtcgcaa cttcgtgaag aagtttctat gaagttgaaa
     1321 gctctaaagc aagattatga gtcgtttatt tctgttaatt taactagctc tctatctgaa
     1381 gtatatagca aatatgcatc tttagaacag gattggctaa ttatagatca cagaggtaat
     1441 gtaaaaattg atactaggtt gccttatatt gttggaaata tttcatctaa atcaattgaa
     1501 gaactttggt tattagttca agaaaagtat aacgattcta ttgttaaaga aaatattaca
     1561 agtgcactag ataataat
//
LOCUS       DAVMJI010000091         1513 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.093, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000091 DAVMJI010000000
VERSION     DAVMJI010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1513
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.093"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..>1513
                     /locus_tag="VYR58_002067"
     CDS             <1..>1513
                     /locus_tag="VYR58_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV3623151.1"
                     /translation="EVDDFTSETGKRIEEYDYKYDDKGNIIAYDDGSALQYETEKLDE
                     IKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEIKATKYDSHSKTMTFD
                     LYANINDIVDGLAFAGDMRFFVKDDNRIKAETKIRMPEKNKETKAEYPYVSSYGNVIE
                     LGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKVTTYNPGKTDML
                     EGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLMSALDGFNIIRY
                     QVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEAIKEDGSMLFID
                     TKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVNESVVDNYLIYG
                     DLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYLQTGYSDLNAKA
                     VGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFDGEIQEQ"
BASE COUNT          599 a          187 c          297 g          430 t
ORIGIN      
        1 gagaagttga tgattttaca agtgaaactg gtaagagaat agaggaatac gattataaat
       61 acgatgataa gggaaatatt attgcttatg acgatggtag tgccttacaa tatgaaactg
      121 aaaaacttga cgaaataaaa tcaaaaattt atggcgttct aagcccatct aaagatggac
      181 actttgaaat tcttggaaag ataagcaatg tttctaaaaa tgccaaggta tattatggaa
      241 atagctataa atcgatagaa atcaaagcga ctaagtatga ctcacattca aaaacgatga
      301 catttgattt atacgctaat attaatgata ttgtggatgg attagctttt gctggagata
      361 tgcggttttt tgttaaagat gataatcgaa taaaagctga aactaaaatt agaatgcctg
      421 aaaaaaataa ggaaactaaa gcagaatatc cctatgtatc aagttatggg aatgtaatcg
      481 aattaggaga aggagatctt tcaaagaaca aaccagacaa tttaactaaa atggaatctg
      541 gtaaaatcta ttctgattca gaaaaacaac aatatctgtt aaaggataac atcattctaa
      601 gaaaaggcta tgcactaaaa gtgactacct ataatcctgg aaaaacggat atgttagaag
      661 gaaatggagt ctatagcaag gaagatatag caaaaataca aaaggccaat cctaatctaa
      721 gagtcctttc agaaacaaca atttatgctg atagtagaaa tgttgaagat ggaagaagta
      781 cccaagctgt attaatgtcg gctttggacg gctttaacat tataaggtat caagtgttta
      841 catttaaaat gaacgataaa ggggaagcta tcgataaaga cggaaatctt gtgacagatt
      901 cttctaaact tgtattattt ggtaaggatg ataaagaata cactggagag gataagtcca
      961 atgtagaagc tataaaagaa gatggctcca tgttatttat tgataccaaa ccagtaaacc
     1021 tttcaatgga taagaactac tttaatccat ctaaatctaa taaaatttat gtacgaaatc
     1081 cagaatttta tttaagaggt aagatttctg ataagggtgg ttttaactgg gaattgagag
     1141 ttaatgaatc ggttgtagat aattatttaa tctacggaga tttacacatt gataacacta
     1201 gagattttaa tattaagctg aatgttaaag acggtgacat catggactgg ggaatgaaag
     1261 actataaagc aaacggattt ccagataagg taacagatat ggatggaaat gtttatcttc
     1321 aaactggcta tagcgatttg aatgctaaag cagttggagt ccactatcag tttttatatg
     1381 ataatgttaa acccgaagta aacattgatc ctaagggaaa tactagtatc gaatatgctg
     1441 atggaaaatc tgtagtcttt aacatcaatg ataaaagaaa taatggattc gatggtgaga
     1501 ttcaagaaca aca
//
LOCUS       DAVMJI010000092         1491 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.094, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000092 DAVMJI010000000
VERSION     DAVMJI010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1491
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.094"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..>1491
                     /gene="pcpA"
                     /locus_tag="VYR58_002068"
     CDS             <1..>1491
                     /gene="pcpA"
                     /locus_tag="VYR58_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV3623152.1"
                     /translation="VILAAYVPNEPILADTPSSEVIKETKVGSIIQQNNIKYKVLTVE
                     GNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVASQAFSYYPDETGR
                     IVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRAFDFSELEEIELPA
                     SLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLTLPKSVKTLGSNLF
                     RLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESYKTPKETKELASYS
                     FNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERLAFYGNLELKELIL
                     PDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEIHIKNKSTEFSVKK
                     DTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETDVAKPKKNSNQGVV
                     GWVKDKGLWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWVKDKG"
BASE COUNT          568 a          202 c          259 g          462 t
ORIGIN      
        1 ggttatttta gcagcatatg tccctaatga accaatccta gcggatactc ctagttcgga
       61 agtaatcaaa gagactaaag ttggaagtat tattcaacaa aataatatca aatataaggt
      121 tctaactgta gaaggtaaca taggaactgt tcaagtgggt aatggagtta ctcctgtaga
      181 gtttgaagct ggtcaagatg gaaaaccatt cacgattcct acaaaaatca cagtaggtga
      241 taaagtattt accgttactg aagtagctag tcaagctttt agttattatc cagatgaaac
      301 aggtagaatt gtctactatc ctagctctat tactatccca tcaagcataa aaaaaataca
      361 aaaaaaaggc ttccatggaa gtaaagctaa aactattatt tttgacaaag gcagtcagct
      421 ggagaaaatt gaagatagag cttttgattt ttctgaatta gaagagattg aattgcctgc
      481 atctctagaa tatattggaa caagtgcatt ttcttttagt caaaaattga aaaagctaac
      541 cttttcctca agttcaaaat tagaattaat atcacatgag gcttttgcta atttatcaaa
      601 tttagagaaa ctaacattac caaaatcggt taaaacatta ggaagtaatc tatttagact
      661 cactactagc ttaaaacatg ttgatgttga agaaggaaat gaatcgtttg cctcagttga
      721 tggtgttttg ttttcaaaag ataaaactca attaatttat tatccaagtc aaaaaaatga
      781 cgaaagttat aaaacgccta aggagacaaa agaacttgca tcatattcgt ttaataaaaa
      841 ttcttacttg aaaaaactcg aattgaatga aggtttagaa aaaatcggta cttttgcatt
      901 tgcggatgcg attaaacttg aagaaattag cttaccaaat agtttagaaa ctattgaacg
      961 tttagccttt tacggtaatt tagaattaaa agaacttata ttaccagata atgttaaaaa
     1021 ttttggtaaa cacgttatga acggtttacc aaaattaaaa agtttaacaa ttggtaataa
     1081 tatcaactca ttgccgtcct tcttcctaag tggcgtctta gattcattaa aggaaattca
     1141 tattaagaat aaaagtacag agttttctgt gaaaaaagat acatttgcaa ttcctgaaac
     1201 tgttaagttc tatgtaacat cagaacatat aaaagatgtt cttaaatcaa atttatctac
     1261 tagtaatgat atcattgttg aaaaagtaga taatataaaa caagaaactg atgtagctaa
     1321 acctaaaaag aattctaatc agggagtagt tggttgggtt aaagacaaag gtttatggta
     1381 ttacttaaac gaatcaggtt caatggctac tggttgggtt aaagacaaag gtttatggta
     1441 ttacttaaat gaatcaggtt caatggctac tggttgggtt aaagacaaag g
//
LOCUS       DAVMJI010000093         1413 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.095, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000093 DAVMJI010000000
VERSION     DAVMJI010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1413
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.095"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            96..617
                     /locus_tag="VYR58_002069"
     CDS             96..617
                     /locus_tag="VYR58_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623153.1"
                     /translation="MRSYINKARYKEVNVQEIDYPTFYDEENGKLIIVYNEQITQDDS
                     LREKINNISKSIREIIKNHVEYNLWNTYLLVLVDINLFNEKYYYVERDVRNLRKYVIQ
                     NEKDISRIPFINMAEHKIDNDGVKGHSYSPSVQIQDLYKNLMAKDGDRKKLSKSKISE
                     TLKELKFLGENDD"
     gene            607..>1413
                     /locus_tag="VYR58_002070"
     CDS             607..>1413
                     /locus_tag="VYR58_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV3623154.1"
                     /translation="MMIRLKQVIIKNFRNFQGTHQFDFSKDVTIFLGDNGNGKSSVFD
                     AIQWCLTGNVERFKNVSSADIMKSVLINKNSDECAVEIIFTTNLSLKRVAPRYGNIRV
                     SCNYGNEIVRGDKNVKEYIEGLFKNSKGEKFDIQEFLKSSLLAQDQVLDFISSDTAND
                     RYRVLSSILGMNEITNLKENYEKVRSLLDNEMEKKADFVKSLQKEIDLQESKIDYGYK
                     YLITDEISNSSFEDKQKENNELQKSKAQIEERLTRFNLQYNNIKQDIGDLN"
BASE COUNT          583 a          131 c          268 g          431 t
ORIGIN      
        1 tgaaataaac gatgatagaa taaaatataa taatttagtg gagatgaaaa ataaaattgt
       61 tgaggagtta cagttagaag gtattatttg aagagttgag aagttatatt aataaagcac
      121 gatataaaga ggtaaatgtt caggagattg attatcctac cttttatgat gaagaaaatg
      181 ggaaattaat aattgtatac aatgaacaaa ttacccaaga tgattcgctt agagagaaga
      241 ttaataatat atcgaaaagt attagagaga ttatcaagaa tcatgttgaa tataatttat
      301 ggaatactta tttgctagta ttagttgata taaatttgtt taacgaaaaa tattattatg
      361 tcgaaagaga tgtaagaaat cttaggaaat atgttatcca aaatgaaaag gacatttcac
      421 gaatcccgtt tataaatatg gcagaacata aaatagataa cgatggagta aaggggcata
      481 gctattcgcc ttcagtacag attcaagatt tgtataaaaa tttaatggca aaagatgggg
      541 atagaaaaaa attatcgaaa tctaagatat ccgaaacttt aaaagagtta aaatttttag
      601 gagaaaatga tgattagatt gaagcaagta ataattaaaa attttagaaa ttttcaaggt
      661 acacatcagt ttgatttttc aaaagatgtt actatctttt taggagataa tggaaatggg
      721 aaaagttcag tttttgatgc aattcaatgg tgtttaacag gaaatgttga aagattcaag
      781 aatgtcagta gtgcagacat catgaaaagt gtactaataa ataagaactc tgatgaatgt
      841 gcagttgaaa ttatctttac aactaattta tctttgaaaa gggtagcacc aagatatggt
      901 aatattagag tttcttgtaa ttatggcaat gaaattgtac gaggagataa aaatgtcaaa
      961 gaatatatcg agggattatt caagaattca aaaggtgaaa aatttgatat tcaagaattt
     1021 ctgaagtcct ctttacttgc tcaagatcag gtgttagatt tcatttcaag tgacactgcg
     1081 aacgatcgtt atagggtact atcttcgata ctaggaatga atgaaataac taacttaaaa
     1141 gagaattacg aaaaggttag gagtttgctg gataatgaaa tggagaaaaa agcagatttt
     1201 gtgaaatctc ttcaaaagga aattgatctt caagaatcaa aaattgacta tggatataaa
     1261 tatctgatta ctgatgaaat aagtaattct agtttcgagg ataaacaaaa agaaaataat
     1321 gagctacaga aaagtaaagc tcagattgaa gagagactta cacgatttaa tttgcagtat
     1381 aataatatta aacaggatat tggtgatcta aat
//
LOCUS       DAVMJI010000094         1377 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.096, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000094 DAVMJI010000000
VERSION     DAVMJI010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.096"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            48..>1377
                     /locus_tag="VYR58_002071"
     CDS             48..>1377
                     /locus_tag="VYR58_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEV3623155.1"
                     /translation="MNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPN
                     ELHKLIEKIAPKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGD
                     FSKKNIVLKEDDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNT
                     FKLDAKNAYFYTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLE
                     VLSENRSQDVNNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQ
                     LRFEIDGHEELRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKA
                     KFRELANIAFRQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQIIN
                     SVTGDEKKIIEFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSA"
BASE COUNT          522 a          161 c          252 g          442 t
ORIGIN      
        1 ctaatctacc aacttgggga gaattgattc aatcattaaa aaaagaattg aacataccag
       61 aagaaagaac agatagtcca ctgagaattg ctcagtatta ttatgatact tttgggaaaa
      121 atcagtacac aaagaagata gaagaaattt tctttaagaa gggattgagt aaaccaaatg
      181 agttacataa attaatagaa aaaattgcac caaaacatat tattacgaca aactatgatt
      241 cacttctgga gagtcaattt gaaagtggct tgttaaagta caatgtagtc gctgaggata
      301 aagacatccc ttatacgagt tcggaaagat acttgattaa aatgcatggt gacttcagta
      361 agaaaaatat tgttttgaaa gaagatgatt atttagacta tcatttgaac ttcccaatga
      421 tttctacttt aatccagtca ttgataatga atcatactct attgtttgtg gggtattctc
      481 taagtgattc gacttttaat tcaattttta gaatgattca aaatacattt aaattggatg
      541 ctaaaaatgc ttatttttat actcccgagg aaccgtctat gatcattcga gagtattata
      601 agaagcaagg aattttcatt atctctaatg aagagaatct aggtcaggag acatcagaaa
      661 aacagaacaa attgtattgc aggacaaaag attttttaga ggttctatca gaaaaccgaa
      721 gtcaagatgt aaataatgct gatgatttat ggaatcaact ggctttttta gatagactta
      781 gttttattga tgcgaaagat ttttctagat attctgattt aaagaaaagg gctttaaact
      841 gggatgatga gtattgctgg tttggaaatg atcaattaag atttgaaatt gatggtcatg
      901 aagaattacg aattatggta tctaaaaaat ctttattaaa tcgctttcta gatatggaga
      961 ttggtgagcc tagggattta aaggggaatc gattcttaag taaggctttt aagttgtatg
     1021 aagaaaaaca atattcttta gcaaaagcaa aatttagaga actagctaat atagcatttc
     1081 gtcagaaaga ctattttaat ttcttagttt gtgaatttaa ttttcagcaa attcaaataa
     1141 ttgatagata cgaaaaaaca cctagttatg cagagccact ttatgatgga gaattaagcg
     1201 aattaacaga acaaattatt aactcggtta caggagatga gaaaaagatt atagaatttt
     1261 ttagagattc aatccttaac ttcaattttt tatatagaaa attagaaact attaatgaat
     1321 tatttgatga aattcgtgaa gagcatgaaa gctatagaag aggaggatgg tctgcta
//
LOCUS       DAVMJI010000095         1364 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.097, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000095 DAVMJI010000000
VERSION     DAVMJI010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.097"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..212
                     /locus_tag="VYR58_002072"
     CDS             <1..212
                     /locus_tag="VYR58_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623156.1"
                     /translation="EYQEINHIKYSVDFVNKELGIDLSIEIDKLIKQGEKPSVIAQIK
                     KFQDQVNKDNEYREMMKNKKMDQER"
     gene            286..459
                     /locus_tag="VYR58_002073"
     CDS             286..459
                     /locus_tag="VYR58_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623157.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            645..1172
                     /locus_tag="VYR58_002074"
     CDS             645..1172
                     /locus_tag="VYR58_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEV3623158.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKGIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            1299..>1364
                     /locus_tag="VYR58_002075"
     CDS             1299..>1364
                     /locus_tag="VYR58_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEV3623159.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRI"
BASE COUNT          717 a          180 c          211 g          256 t
ORIGIN      
        1 atgaatacca ggaaattaat catataaaat attcagtaga ttttgtaaac aaagaacttg
       61 gtatagattt atccatagaa atagataagc taataaaaca gggagaaaaa ccaagtgtaa
      121 tagcacagat taaaaagttc caagaccaag ttaataaaga taatgaatac agagaaatga
      181 tgaaaaacaa gaaaatggat caagaaagat aagacctggt aaaaatatct tatccaagct
      241 ataatatgac caaacaacta aagtcagatc taggaggtaa tagagatgaa taaaaggcaa
      301 gagctaatag atgaactcat aaaagcaaat gaagatggaa catacaaaac ctataaaagc
      361 acagaagaaa taaaagcaat gaacaatgaa gaaatacaga ttatatattc caacatgaaa
      421 aactatctat cagacaaaag aacacacata aactattaaa ggtggaaagg tagtgtaagc
      481 tatttttaaa agtataaaag gtacaaagac ctaagaaata tataaaaaca tcaaaataaa
      541 gtattccacc accaagaaca ataaaataaa aacaagcaaa gggaagtata gaaaaattaa
      601 aacctatact tccctttttt aattcaaaca aaggagagaa aagcatgata aacgaagaaa
      661 taagcaagga agcaggtcaa gcagcacaaa ccataatatc atacacaata aaggcaacaa
      721 aagaatcaat caatttagaa aaagaaataa gaaaaaagat gaatgaaact ttagaaaaag
      781 caaatggaaa cttaaaaagt cttatgggcg atgaaatgaa aataaaagat ctctacaaga
      841 aaggacaact agaaaatata agcatagatc aaatcgacct caaagactta aaaaaagaac
      901 taaacaaact tggagtaagt ttctcagtaa tgaaaaacaa agaaagcaaa aactatgaaa
      961 tattcttcca agccaaaggc ataaaagtaa tggaatatgc ctttaagcaa gtcatagcca
     1021 aggaaaataa aaaagaaaaa gaaagtatcc taaaacaaat aaagaaatac aaagacctat
     1081 ccaaaaacaa agataagaca aaagaaaaag gaaaaaggaa agtaaaagaa aaagtaaaac
     1141 caaacaaaaa agatatgacc agagaaatct aaagggagta acgaaaagtt acacccttaa
     1201 ataaccataa taacaagact tccgaaaaac agaagtccag aattccgaaa atcggaaatc
     1261 aagaatttcg attatcgaaa atcaagaaag gagcagatat ggcaacaaac aaaagatact
     1321 attggataaa attaaaagaa gaatttttca cagacaaaag gata
//
LOCUS       DAVMJI010000096         1293 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.098, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000096 DAVMJI010000000
VERSION     DAVMJI010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.098"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            40..585
                     /locus_tag="VYR58_002076"
     CDS             40..585
                     /locus_tag="VYR58_002076"
                     /inference="COORDINATES: protein motif:HMM:NF016852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEV3623160.1"
                     /translation="MPKNKVYNTGETDIELKNKYNYEGSELRKVQVRMIDMLSFLNDI
                     CKENNITYFIAFGTLLGAIRHGGFIPWDDNLYIYIYIYINDKGLKKLRKIINNGNYPY
                     VIQDYSSDKGFVRYYSVLRDTNSEYIKNEYQHNQRKYRGVQIDLFPYGYGVMKWGERL
                     IGKIYGFNEKIFLGKIKCWQH"
     gene            570..1187
                     /locus_tag="VYR58_002077"
     CDS             570..1187
                     /locus_tag="VYR58_002077"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623161.1"
                     /translation="MLAALIFYLTKEVIIPFLKVISKINGRKKVIYWLLTILGLWMIT
                     LTPIFENIVGAILKVDGVGRGSDSLTIRAIGRQLYWEQLNETTLKLLFGTGYPNYNYA
                     LAFQRTGFFKQYFFNRQWFYDIYIFGIVGSSIMGLLFLKYLKNSIKYDRQSADMIPLM
                     YIISLLIVAYNIILWYWNADGTFILLIMICALEHGEQLLHQKNGV"
BASE COUNT          463 a          126 c          233 g          471 t
ORIGIN      
        1 aatagatgat aaattgatat gataaagagt tttttgatta tgccaaaaaa taaagtttat
       61 aatactggcg agacagacat tgagttgaaa aataaataca attatgaagg tagtgagttg
      121 aggaaagttc aagttcgtat gattgatatg ctttcttttt tgaatgatat atgcaaagaa
      181 aataacatca cctatttcat tgcttttgga actctattag gagctattag acatggaggc
      241 tttattccat gggatgataa tctttatatt tatatttata tttatattaa tgataaaggt
      301 ttaaaaaaac ttagaaaaat aattaataat ggaaactatc cctatgttat tcaagactat
      361 tctagtgata aaggatttgt aaggtattat agtgttctca gagatactaa ctctgaatat
      421 ataaaaaatg aatatcaaca taatcagcgt aaatacagag gtgtacaaat tgacttattc
      481 ccttatggtt atggtgtaat gaaatggggt gaacgtctta ttggaaaaat atatggtttt
      541 aatgaaaaaa tatttttagg gaaaataaaa tgttggcagc attaattttt tatttaacta
      601 aagaagttat aattccattt ctgaaagtaa ttagtaagat taacggaaga aagaaagtaa
      661 tttattggtt gctgacaatt ttgggactgt ggatgattac tctaacacct atttttgaaa
      721 atattgttgg agctatttta aaagtagatg gagtaggtag aggaagtgat tcattgacta
      781 ttcgagcaat tggacgacag ttatattggg aacaattgaa tgagacaact ttaaaacttc
      841 tttttggaac aggataccct aattataatt atgctttagc ctttcaacgt acaggttttt
      901 tcaagcaata tttttttaac agacaatggt tttatgatat atatatattt ggtattgtgg
      961 gttcctcaat tatgggatta ttatttttaa aatatcttaa aaattcaata aagtatgata
     1021 gacaatctgc agatatgatt ccgttgatgt atattatttc tttactaatt gtagcctata
     1081 atattattct ttggtattgg aatgcggacg gtacttttat attattaatc atgatttgcg
     1141 cattggagca tggagaacaa ttattacatc agaagaatgg agtgtgattg gatgaattta
     1201 aataaagaag ttagatggaa ggataagcaa tatattgctt ttgatttttt tgatacaact
     1261 atccatagaa attgtcatcc tgaagtgatt tta
//
LOCUS       DAVMJI010000097         1260 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.099, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000097 DAVMJI010000000
VERSION     DAVMJI010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1260
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.099"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(<1..>1260)
                     /locus_tag="VYR58_002078"
     CDS             complement(<1..>1260)
                     /locus_tag="VYR58_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004182574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HEV3623162.1"
                     /translation="KSISKNAILNIILTLTNIVFPLITFPYISRILNPSGIGAISFFS
                     SIGSYGVLVASLGISTYGIRVIAKNRYHKDKITKIFQELIVINSVMSIIVTFFLVLMS
                     FRLEQLSSEKGLLIITCITILSSPFNLNWFYSGIEEYSYITKRSIFFKLVSLILTFLF
                     VKSKDDYIIYAVIILFSTLASNFINILESRKYINFNLRRNLEFRYHLKPMWYLFASLL
                     AVNIYTNLDSVMLGIINGNDAVGIYSIASKVKWILLSVVTSVSLVLLPRLSFYSNKYD
                     ETKFNNILRKSSTIIFMISIPLTIFFMIKAKESILLLGGEQYIQAVLAMQILMPILII
                     SGFSNIIGNQILIPTGNEKYFMRAVSIGAIVNLCLNLLLMPILGIIGGAIATLCAESV
                     QMIIQFYFSRNKLMGNISLNSIKKVAY"
BASE COUNT          500 a          198 c          144 g          418 t
ORIGIN      
        1 aataggctac ttttttgatt gaatttaatg aaatattacc cattaattta ttacgagaaa
       61 aataaaattg aataatcatt tggactgatt ctgcacaaag agttgcgatt gcacctccga
      121 taattcccaa aataggcata agcaacaaat ttaaacataa atttactatt gcccctatag
      181 aaactgctct cataaaatat ttctcattac cagtagggat caatatctga ttacctataa
      241 tattggaaaa acctgatatt atcaagatcg gcattaatat ttgcattgct aaaactgcct
      301 gaatatactg ctctccacct aacaataata tactctcttt cgcttttatc ataaaaaaaa
      361 ttgttagagg aattgaaatc ataaaaatta ttgtagatga ctttctcaaa atattattaa
      421 acttcgtttc gtcatactta ttgctataaa atgataatct gggtaataaa actaaactca
      481 ctgaagtaac gactgataat aaaatccatt ttacttttga tgcgattgag taaataccta
      541 ccgcatcatt tccattaata attcctaaca tcacagaatc caaatttgta taaatattaa
      601 ctgcaagtaa cgaagcaaat aaataccaca ttggttttag atgatatcta aattctaaat
      661 tccttctcaa attaaaattg atgtattttc tactctccaa aatatttata aaattggaag
      721 ccaatgttga aaacaatatt atcacagcat atataatata atcgtcttta cttttaacaa
      781 ataaaaaggt taatatcaat gaaactaatt taaaaaatat tgaacgtttt gttatatatg
      841 aatactcttc tattccacta taaaaccaat tcaaattaaa aggagaggac aaaatagtaa
      901 tacatgtgat tattaataaa cctttttctg aacttaactg ctctaatcgg aaactcatta
      961 aaacaaggaa gaacgtcact ataatagaca ttacactatt aataactatc aattcttgga
     1021 atattttagt tatcttatct ttatgataac gattctttgc aatcacccga atcccataag
     1081 ttgaaattcc aagcgaggca actaaaacac cataagaacc aatagatgaa aaaaaagaga
     1141 ttgcgcctat tcctgacgga ttcagaattc tagaaatata aggaaaagta attaatggaa
     1201 acacaatatt tgttagtgtt aaaataatat tcaaaatagc atttttactt attgattttt
//
LOCUS       DAVMJI010000098         1221 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.100, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000098 DAVMJI010000000
VERSION     DAVMJI010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1221
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.100"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..574
                     /locus_tag="VYR58_002079"
     CDS             <1..574
                     /locus_tag="VYR58_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3623163.1"
                     /translation="CFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            594..1221
                     /locus_tag="VYR58_002080"
                     /pseudo
     CDS             594..1221
                     /locus_tag="VYR58_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          426 a          132 c          231 g          432 t
ORIGIN      
        1 ttgttttcaa cgtaatgaaa agtatttaat tttaggtgaa agtggaagcg ggaaatctac
       61 attattaaaa ttattgaatg gctttttgag agattatagt ggagaattgc gattctgcgg
      121 ggatgatata aaaaaaacct cctatttaaa tatggtttcg aatgttctat atgtagatca
      181 aaaagcttat ttgtttgaag gtacgattag agataatatt ttattggaag aaaattatac
      241 tgatgaagaa atactacagt ctttagagca agttggtttg agtgtaaaag attttcctaa
      301 taacatttta gattattatg ttggtgatga tgggagatta ctgtcaggag ggcagaaaca
      361 aaaaattact ttagctagag ggctaattag aaataagaaa atagtattaa ttgacgaggg
      421 aacttctgct atcgatagga gaacttcgtt agcgattgaa cgtaagatat tagatagaga
      481 ggatttgact gtcattattg ttacccatgc tccgcatccg gaacttaaac aatattttac
      541 taagatatat caatttccaa aggattttat ttaagaatat aggggaggga aacatgagat
      601 tctattgtga agcttatgag gtaattactg aagagaaaaa agtatcattt ttttatgtag
      661 atgaaaaacc cttaaggtat ctgttatttg actatatatt tctactagtt ctagctaaaa
      721 aaatatccca atcttagatg gagtttccaa taagcaagtt gctccaacgt tgctgcatca
      781 cttttctttg gaaattgaaa agaattttat cgatttttgc tataaaaata tggatctcat
      841 cctaaaaact caaagtatat ctttgtgtca tagagaagag cttattattg tagatgtttc
      901 agatgactct aaatttggtg ttttttacaa gcgttttaga acactggttg ataaaaataa
      961 cggaaaatat gtttgtgttt ataatttcag tcgtgtttca gatatactgc aaaactggaa
     1021 aaattattgc aatcgaaaat tttcggttac gtttactgaa agccaatttg aattatttaa
     1081 gcttttatat aatcaaaaaa attttaaaac aatttcgttg ctatttggaa aaaaattgtt
     1141 gctggaggaa ttatctatta tagcgatctt actaatatag aatacttttg tattttttgg
     1201 tgggatagta tgtttgggaa a
//
LOCUS       DAVMJI010000099         1212 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.101, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000099 DAVMJI010000000
VERSION     DAVMJI010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1212
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.101"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            198..>1212
                     /locus_tag="VYR58_002081"
     CDS             198..>1212
                     /locus_tag="VYR58_002081"
                     /inference="COORDINATES: protein motif:HMM:NF013094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEV3623164.1"
                     /translation="MDIGTESNKLVRVKMGVYVKNKLCYIIFQEQSILVVNNDIAKYY
                     VFEDSPVLNCLLSALENNILTNDKLDRISQQLSENIDILFKVLNELIKLKIVFYVDET
                     EEEFNINHITDERFSTEILYLNKFTSKPYQLLQAIQSKRVVIIGAGALGSSLALKISA
                     IGVRDIICIDGDKIELDNLTRQILYTPGDIEKNLFKVSALESRIKDFFPSSQFQGIKS
                     YITSYDDCVNYIPHNSDLIIQTADYPIGKLDDWINKVSLKYNIPVIFSHFGSVGPFLI
                     PSETGCLRCLDQFLDTKTNGLNSITKNFFQNIPNSKSPSFVTGTQLNELLILDIIKKF
                     WISD"
BASE COUNT          446 a          169 c          204 g          393 t
ORIGIN      
        1 aacaccctag tttttcatag gaggatttgc aatgaacacc gatactagca aagttgtagt
       61 ggacaacaca tctgaggata tggatatatc tattcttaat tttaaagagg tagatattgc
      121 ttatactgct catgaaccgg gtcgctgtta gttaaaagga gagtgggctg cagaccactc
      181 tttttatata tctttttatg gacattggaa ctgaatccaa caaattagtg agggtaaaaa
      241 tgggagtcta tgtaaaaaac aagttatgtt atataatttt tcaagaacaa tcgattctag
      301 ttgttaataa tgatattgca aaatattacg tatttgaaga ttcaccagtt ttgaattgtt
      361 tgttatctgc acttgaaaat aatattttaa caaatgataa gctagataga atatcacaac
      421 aactttctga aaatattgac atactcttca aagtgttaaa tgaattaatc aagctaaaaa
      481 ttgtattcta tgtggatgaa acagaggaag aatttaatat aaaccatatt acagatgaaa
      541 gattctcaac agaaatacta tatctaaata aattcacttc taagccatat caattactac
      601 aagccattca aagcaagagg gtagtaatta ttggtgcagg agcattaggt agctcactag
      661 cgttgaaaat ttcagcaata ggtgtaagag atattatctg tattgatgga gacaaaattg
      721 aactagataa tttgacacgg caaattttgt atacaccagg tgatattgaa aaaaacttat
      781 ttaaagtttc agctttagaa tcaagaataa aggacttttt tcccagtagc caatttcaag
      841 gaattaaatc ttacatcaca agttatgacg attgtgtgaa ttatataccc cacaatagcg
      901 atttgattat tcaaacagct gactacccta tagggaaact agatgactgg ataaataaag
      961 tatcactaaa gtataatatt ccggtaatat tttcccattt tggtagtgta ggcccatttc
     1021 tgattccatc tgaaactggt tgtctgagat gtttagatca atttttggat actaaaacta
     1081 acgggttaaa ttcaattaca aagaattttt ttcagaatat ccctaactca aaaagtccat
     1141 catttgtaac aggtacacaa ttgaatgaat tattaatttt ggacataatt aaaaaatttt
     1201 ggataagtga tg
//
LOCUS       DAVMJI010000100         1144 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.102, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000100 DAVMJI010000000
VERSION     DAVMJI010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1144
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.102"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            50..1087
                     /locus_tag="VYR58_002082"
     CDS             50..1087
                     /locus_tag="VYR58_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623165.1"
                     /translation="MENNHSEVQKNKLTIDKVPVQNKKLTEALRVFHETLNHSRLIEV
                     QNSMLQANKAAETALASFNFSKQIAETTKPFLTEINSATSILNNQAYLKILSETEAAV
                     SSILLKTQIDNIGQILDPIHNIFDKSTFNFTESLKEFLKEYHAPYSEIEAEAITLNIE
                     KLAEEGWVIYHSYSDDYRTICTIDFEELIKEWQTLLKEDLEDKELIQELKDLTYYSEP
                     LIDSMIESYRSQNYYAAYTLATIAIDGALNRFSEPFSNKKIIPVGKSSVDLLNKQIVN
                     KTFTDISLFHWLFKFFSYTNNFTLEEPNRNMISHGRWERPLFETDFLKLFNVLLCILD
                     NFEFFQGDLLK"
BASE COUNT          442 a          161 c          176 g          365 t
ORIGIN      
        1 aacacttagt ggtataatta aaacatgaca tatagaaaga aatagcccta tggaaaacaa
       61 tcatagtgaa gttcaaaaaa acaaattgac aattgataaa gtcccagttc aaaacaaaaa
      121 gcttacagaa gcccttagag tttttcatga gacacttaat cattcaaggt tgattgaggt
      181 tcaaaatagt atgctacaag caaataaagc tgctgagact gcgttagcaa gttttaattt
      241 ttctaagcaa atagctgaaa ccactaaacc ttttctaaca gaaataaact cagccacgtc
      301 tattttaaat aaccaagcat atcttaaaat tctatctgaa acagaagcag cagttagttc
      361 aattctttta aaaactcaaa tagataatat tggacagata cttgatccta ttcacaatat
      421 ttttgataaa tccactttta attttaccga aagtttaaaa gaatttttaa aggaatacca
      481 tgcaccttat tctgaaatag aagcagaagc aatcacttta aatattgaaa aacttgctga
      541 agaaggttgg gtaatctacc atagctatag tgatgactat agaacaatct gcactataga
      601 ttttgaagaa ttgataaagg agtggcaaac tctattaaaa gaagatcttg aagataagga
      661 gcttatacaa gagttaaaag acttaacata ttactcagaa cccttgatag attctatgat
      721 cgaaagttat agaagccaaa attattacgc tgcttatacg cttgctacta tagctattga
      781 cggtgcatta aacagatttt cagaaccatt ttcaaataaa aaaattatac ctgttggaaa
      841 atcttctgtt gatttattaa ataaacaaat tgtaaataag acgtttactg atattagtct
      901 atttcattgg ttattcaaat tttttagtta tactaacaac tttacattag aagaacctaa
      961 caggaatatg attagtcatg ggagatggga gcgtccactc tttgaaacag attttttaaa
     1021 gttatttaat gttcttttat gtattctaga caactttgag ttttttcagg gagatttgtt
     1081 aaaataacag tgaattaacg ctatttgtta aataaagaaa gggatttgaa aatggatatt
     1141 attg
//
LOCUS       DAVMJI010000101         1138 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.103, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000101 DAVMJI010000000
VERSION     DAVMJI010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.103"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(<1..990)
                     /locus_tag="VYR58_002083"
     CDS             complement(<1..990)
                     /locus_tag="VYR58_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV3623166.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEA"
BASE COUNT          410 a          195 c          142 g          391 t
ORIGIN      
        1 tgcttcatat aacggaaaat ctctattcac ctcatttggt tcgatatcat tcattttatt
       61 tgactcaatt ggattaattg aatacaattt taaaaaaata ggcttcgtac caataataga
      121 ggataattga cctcctaatt cacctagcgc tgtaaaaata acacctgtta gtgctcctat
      181 tgcttcaata gtaccaattt tcactattcc ttttattgca agatagcctg ttaaaaaaac
      241 gagagatatc tgaaaaaaaa tattgagaaa gaagctaata gcgcctgcta acgtttctac
      301 agttgtcttt ctttgtataa ccatctttaa taaaattcct gcttctttaa ttttcttagg
      361 caatacatat aaaagattca aggacgctaa cacatcaaat ccattcaata tagtctcact
      421 agattttaaa aaagcttcat tttggctagt taaatttaga ctaacttctc gcattttcga
      481 tgcaaagatt tttggtacaa gtagcataat cattaatgaa aacaaggtgg ctacagtcaa
      541 tgaccaatga tagtgattaa gagtcacaac tgcaaatata gtaccagaaa ttccttttat
      601 tactaaaaaa agttgtttaa aagcctgatc atttaaagtc tgaacatcat tatttagcca
      661 cgaaagatat gttcctgatg atttactatg aaattcttga taggtagagt tagagatgtc
      721 tgtggcaact ctatttcgaa tctctagatt aaactcttgg atcacttcaa cctgataatt
      781 tttcactacc cagtcaagga atattatccc acaccagaca atcatttggt agattgacaa
      841 tttcaaaaac cgctctaaat tcatcgcaat taattcattc aacaccagag cattaatagt
      901 tgctgcataa attagcaata attgaccagc aacaataaat atcgttaata aactaaattt
      961 ttttatattt gattttataa tagtatacac aatagtttct cactttctaa attttaattg
     1021 aacatagttg tcatatatac aatagaaaaa accaaaatga tataataaca tatatttcaa
     1081 aaaagaaatt cgttaaaaat tttttcttct cttgccttct tgattacttt taaagcct
//
LOCUS       DAVMJI010000102         1135 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.104, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000102 DAVMJI010000000
VERSION     DAVMJI010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1135
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.104"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(<1..388)
                     /locus_tag="VYR58_002084"
     CDS             complement(<1..388)
                     /locus_tag="VYR58_002084"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623167.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIK"
BASE COUNT          483 a          174 c          136 g          342 t
ORIGIN      
        1 ttttaattcc cctatccttc aataatcggt ataaaagata ctgactcata ccttgatacc
       61 aaataaaatt cggtatttca ataagagcat gaggtaatat tccttttatt gtagctacta
      121 ttccaatcat ctgaccagat atacccaatt gtattcctaa agatagcaaa tcaaaaagtt
      181 gcaataaggg cgaaatcgga aaacagaata gatatagcaa aaaatttgta gaatttgcct
      241 gtaaaactgt caatgtaaat tgtaattcca gtttcggagg tatagtagca aaagtctcat
      301 tttttaatat aaagcttaaa agtaaaccta gtaaaaaaca gactatacaa aataacacat
      361 agtaaatcag aaaaccactt tttctcatct aatgccccct actaaaatta caaatattat
      421 cagaaaacaa tataaaacca gaaaactcca tctcaataaa ctaactgtac ctttaattaa
      481 aaatagagct ttcttataat agacataggc tataaaataa ttgaatggaa tcaataacaa
      541 attcaacaaa atacttttta tatcattact ataacttgtc accggaatca aacataacaa
      601 caatgaaaat tgtaagaaag agattaaatg cgtcaacatc attagttgtg cattcttaaa
      661 aaagaaattc attttagaat gattaagagc agataattga agtaaagcta gatctacccc
      721 aattgaggat ttatgattcc ctattattgc ctccattaat gtaatatata ttgaggtata
      781 aagaaataat attggtattt ttgtgtcatc aattgataac atcgtcatca tataccaaaa
      841 tagataggaa agaagaatac taatcaaaat aaaagaaaaa gttaaccctt tatttaacca
      901 acaaaaacga agcaatataa atagactgct acgaaatctt ttttgactca ttcgactgct
      961 tttaaaatag aaattactcg catgattatc taatatcccc atgactaaaa taaaataatt
     1021 gagtagtatg acataaatta caacttgtcc ttgttctata gacaatagtc ctatagataa
     1081 aaataagaac aatttactta taattgaaaa caaactaggt agaattaaag aaata
//
LOCUS       DAVMJI010000103          993 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.105, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000103 DAVMJI010000000
VERSION     DAVMJI010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..993
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.105"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            105..287
                     /locus_tag="VYR58_002085"
     CDS             105..287
                     /locus_tag="VYR58_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV3623168.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            297..662
                     /locus_tag="VYR58_002086"
     CDS             297..662
                     /locus_tag="VYR58_002086"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV3623169.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            659..993
                     /locus_tag="VYR58_002087"
                     /pseudo
     CDS             659..993
                     /locus_tag="VYR58_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
BASE COUNT          412 a          122 c          166 g          293 t
ORIGIN      
        1 taacaagagg atagaaatga ccgaattaga aagaaaaaat cgaaaaatta gctaagaaat
       61 attctgataa cttaaacatc aaagttcaag agagagttcg tgaaatggca aatgataata
      121 agagccatta tttgatatac agagttttag gtatttcatt tgaagaagga gaaaatatcg
      181 atttgtatca aaataaaggt cgttttttat acaaatatgc tggttcattt ttagaagaag
      241 ctgcagtact atcctttaac gaaaaatttg gtacagaaaa tacttaaaaa gttaacattc
      301 ctaattctga aagtacaaaa cctaagactt ttgaaattga ttgtttagtc ggagaaaaac
      361 acgcatacga aataaaatgg tgggatgcaa ctacagatgg agaccatata actaaagaac
      421 acactagaat aaaagttatt cataacaaag gatatatacc aattcggtta atgttctact
      481 atccaaatag aactcaagct ataaaaattc agcaaacttt agaaacattg tataacggta
      541 ttggagggaa atattattat ggagattctg cctgggaaca tttaagagca gtgaccggta
      601 ttgatttact tagtattcta acagatattg caaataaaaa aacaggggta aaatcaaaat
      661 gacagtatta aaaggagata acttagaaat attaaaaact attgaatcct caagtattga
      721 tttaatctat atggaccctc ctttctttac acagaaaacc caaaaattat ctaataacaa
      781 aaatattatg tattcattcg aagatacgtg gacttcgatt gaggattaca aagaattttt
      841 gtctgtaaga ttagaagaat gcaaaagagt gctaaaaaat agtggcagta tttcgttcat
      901 tgtgataaaa ttgcaaatca tcatattaga ttaattttag ataatatctt tggagcagat
      961 atgtttcaaa gcgaaattat atggaactat aaa
//
LOCUS       DAVMJI010000104          969 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.106, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000104 DAVMJI010000000
VERSION     DAVMJI010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..969
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.106"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(<1..59)
                     /locus_tag="VYR58_002088"
     CDS             complement(<1..59)
                     /locus_tag="VYR58_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HEV3623170.1"
                     /translation="MKKISKFLPILVLVMDIII"
     gene            139..>969
                     /locus_tag="VYR58_002089"
     CDS             139..>969
                     /locus_tag="VYR58_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEV3623171.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKLHYTDH
                     F"
BASE COUNT          348 a          158 c          134 g          329 t
ORIGIN      
        1 atgatgataa tatccatcac caaaaccaaa atcggtaaaa attttgaaat tttcttcata
       61 cttggacttc ctttccgttt ttatttattg tacaataaat aaaaacggat ttaatttttg
      121 ttgggaaaat gggaaattat gaaatcaaaa cttggcatca cacttagaaa agttcgtaaa
      181 ggaaaacaaa ttagtctatg ctctgtagca gatgaacatc tttcaaaatc acaaatatct
      241 cgttttgaac gtggggagtc agagatatct tgtattcgac taatcaatat tttagacaaa
      301 ttacatatta ctttggatga gttccttgtt ttacacaatg acgactatac cagttccgaa
      361 tcatttgcta atctagtaca gtacattcgt aagcaatatt catcacaaag tatcaataat
      421 atagcatgtc tactttctga tacttctgat tacactctaa attcttttga gaaaacaatg
      481 gtaaaatcta ttttacacac aatggattcg aacatcattc catcagatga agagcttctt
      541 catctgacag actatctttt caaagttgaa aaatggggct attatgaaat cattttatta
      601 ggtaactgtg tacgcacaat taactacaac tcctacttct tattaactaa agagatgtta
      661 aataactata tttactcatc tctgaataaa actaataagc agattgtctc tcagcttgct
      721 attaattgct tcattctaag cattgataag gaagaatttt ctaattgctc ctatttaatt
      781 agtaagataa agacattgtt ggacaatgaa ctaaactttt atgaacaaac agtttttctc
      841 tatgcaactg gttactttga atttaaacgt tgccaatcaa ccagtggaat tgaaaaaatg
      901 aaacaagcca tacaagtctt cgatatttta ggagaagata agttaaaatt acactatact
      961 gaccatttt
//
LOCUS       DAVMJI010000105          965 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.107, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000105 DAVMJI010000000
VERSION     DAVMJI010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..965
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.107"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            25..>965
                     /locus_tag="VYR58_002090"
     CDS             25..>965
                     /locus_tag="VYR58_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV3623172.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAVIRDHFLKYDRAVRCRVKIITMDMFSPYYG
                     LAKQLRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSDKQFY
                     RPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLLFH"
BASE COUNT          315 a          203 c          153 g          294 t
ORIGIN      
        1 aaacaactca ttagaaagaa tcatatggaa caattacatt ttatcacaaa attactagac
       61 attaaagacc ctaatatcca gattttagac atcatcaata aggatacaca caaggaaatc
      121 atcgccaaac tggactacga cgccccatct tgccctgagt gcggaaatca attgaagaaa
      181 tatgactttc aaaaaccttc taaaattcct tatcttgaaa cgactggtat gcctactaga
      241 attctcctta gaaagcgtcg attcaagtgt tatcactgtt caaaaatgat ggtcgctgaa
      301 acttctatcg tcaagaagaa tcaccaaatc cctcgtatta tcaaccaaaa aattgcgcaa
      361 aagttaattg aaaagatttc tatgaccgat attgcccatc agctttccat ctcaacttca
      421 actgttattc gtaagctcaa tgattttcac tttaaacatg atttttcttg tcttcctgag
      481 attatgtctt gggatgagta tgcttttaca aagggaaaga tgagcttcat tgcgcaagat
      541 tttaacaatc tcaatatcat cactgttctt gagggaagaa cacaagctgt catccgagat
      601 cactttctta aatatgatag agccgtccga tgtcgcgtca aaattattac tatggatatg
      661 tttagccctt actatggctt ggctaaacag cttcgctttc acattgtaca acatcttagc
      721 cgtgctatga gtcgtgtgcg tgtccaaatc atgaatcagt ttcatcgaaa atcccatgaa
      781 tacaaggcta tcaagcgcta ctggaaactc attcaacagg atagccgtaa actgagtgat
      841 aagcaatttt atcgtcctac ttttcgtatg catttaacca ataaagagat tttaaacaag
      901 cttttgagct attcggaaga cttgaaacat cactatcagc tctatcagct cttgcttttt
      961 cactt
//
LOCUS       DAVMJI010000106          881 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.108, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000106 DAVMJI010000000
VERSION     DAVMJI010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.108"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(8..81)
                     /locus_tag="VYR58_002091"
     tRNA            complement(8..81)
                     /locus_tag="VYR58_002091"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45..47),aa:Ile,seq:cat)
     gene            complement(95..168)
                     /locus_tag="VYR58_002092"
     tRNA            complement(95..168)
                     /locus_tag="VYR58_002092"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(132..134),aa:Met,seq:cat)
     gene            complement(174..247)
                     /locus_tag="VYR58_002093"
     tRNA            complement(174..247)
                     /locus_tag="VYR58_002093"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(211..213),aa:Pro,seq:tgg)
     gene            complement(263..336)
                     /locus_tag="VYR58_002094"
     tRNA            complement(263..336)
                     /locus_tag="VYR58_002094"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(300..302),aa:Arg,seq:acg)
     gene            complement(346..431)
                     /locus_tag="VYR58_002095"
     tRNA            complement(346..431)
                     /locus_tag="VYR58_002095"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(395..397),aa:Leu,seq:taa)
     gene            complement(439..510)
                     /locus_tag="VYR58_002096"
     tRNA            complement(439..510)
                     /locus_tag="VYR58_002096"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(476..478),aa:Gly,seq:gcc)
     gene            complement(533..605)
                     /locus_tag="VYR58_002097"
     tRNA            complement(533..605)
                     /locus_tag="VYR58_002097"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(570..572),aa:Thr,seq:tgt)
     gene            complement(624..705)
                     /locus_tag="VYR58_002098"
     tRNA            complement(624..705)
                     /locus_tag="VYR58_002098"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(669..671),aa:Leu,seq:tag)
     gene            complement(711..783)
                     /locus_tag="VYR58_002099"
     tRNA            complement(711..783)
                     /locus_tag="VYR58_002099"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(748..750),aa:Lys,seq:ttt)
     gene            complement(808..880)
                     /locus_tag="VYR58_002100"
     tRNA            complement(808..880)
                     /locus_tag="VYR58_002100"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(845..847),aa:Asp,seq:gtc)
BASE COUNT          232 a          257 c          199 g          193 t
ORIGIN      
        1 attcaaatgg accttgtagg acttgaacct acgaccactc ggttatgagc cgagagctct
       61 aaccagctga gctaaaggtc cgacaagatc attatagcgg cgaaggggat cgaacccccg
      121 acctcccggg tatgaaccgg acgctctagc cagctgagct acaccgccat gaatcgggaa
      181 gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca agctgagcta
      241 cttcccgagt taaatagaaa aatgcaccct agaggagtcg aacctctaac cgcctgattc
      301 gtagtcaggt actctatcca gttgagctaa gggtgctcca tattatgccg aggaccggaa
      361 tcgaaccggt acgatcgtta ccaatcgcag gattttaagt cctgtgcgtc tgccagttcc
      421 gccaccccgg cctctctaag cgaacgacgg gattcgaacc cgcgaccccc accttggcaa
      481 ggtggtgttc taccactgaa ctacgttcgc actgttttct tctatctaaa aatgccggct
      541 acatgacttg aacacgcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      601 ccggctcatt tgttatatct taatgcgggt taagggactt gaacccccac gccgttaagc
      661 gccagatcct aaatctggtg cgtctgccaa ttccgccaaa cccgcatata tgacccgtac
      721 tgggctcgaa ccagtgaccc attgattaaa agtcaattgc tctaccaact gagctaacga
      781 gtctaaaata acttgcgtta ccttaaacgg tcccgacggg aatcgaaccc gcgatcttcg
      841 ccgtgacagg gcgacgtgat aaccgctaca ctacgggacc t
//
LOCUS       DAVMJI010000107          880 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.109, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000107 DAVMJI010000000
VERSION     DAVMJI010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.109"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..576
                     /locus_tag="VYR58_002101"
     CDS             <1..576
                     /locus_tag="VYR58_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV3623173.1"
                     /translation="LNKDTGEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGE
                     LEKGYQFDGWEISGFEGKKDAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKK
                     DNPQVNHSQLNESHRKEDLQREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPK
                     TGTASGAQTLLAAGIMFIVGIFLGLKKKNQD"
BASE COUNT          351 a          103 c          169 g          257 t
ORIGIN      
        1 ttaaataaag atacgggaga ggtaagtgaa ttaaaacctc atagggtaac tgtgaccatt
       61 caaaatggaa aagaaatgag ttcaacgata gtgtcggaag aagattttat tttacctgtt
      121 tataagggtg aattagaaaa aggataccaa tttgatggtt gggaaatttc tggtttcgaa
      181 ggtaaaaaag acgctggcta tgttattaat ctatcaaaag atacctttat aaaacctgta
      241 ttcaagaaaa tagaggagaa aaaggaggaa gaaaataaac ctacttttga tgtatcgaaa
      301 aagaaagata acccacaagt aaaccatagt caattaaatg aaagtcacag aaaagaggat
      361 ttacaaagag aagatcattc acaaaaatct gattcaacta aggatgttac agctacagtt
      421 cttgataaaa acaatatcag tagtaaatca actactaaca atcctaataa gttgccaaaa
      481 actggaacag caagcggagc ccagacacta ttagctgccg gaataatgtt tatagtagga
      541 atttttcttg gattgaagaa aaaaaatcaa gattaagaca aaagctatag aaaaaaatgg
      601 tttatgtact gagattagat agtgaggtga tgacatagtt ttgtgaaaac ggccatttat
      661 aactcaatta tttagtttac ttcacttcac tattgatact atttggagtt attaatggac
      721 ttagtttaga taactaatga attgattgaa agggttagta ttgacaatat tggtcatatt
      781 gattagaaaa tagagtctat caaaatttaa aggctaatag aggtgatgag acaatttcaa
      841 ggaattaagt agcgtttggt tgcttaattc ctttttattt
//
LOCUS       DAVMJI010000108          875 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.110, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000108 DAVMJI010000000
VERSION     DAVMJI010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..875
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.110"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..>875
                     /locus_tag="VYR58_002102"
     CDS             <1..>875
                     /locus_tag="VYR58_002102"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623174.1"
                     /translation="CFFQDQKNFNISPFYPDSESRSIEETKQMISASFGSKVINYNDN
                     NEDFLDQAFENFNMRHIPHESLEEKVVRNIPISLGFVNNQLSQDMLDHIISEFFKSCY
                     NPEDASVQLISGERLNKLKGIIKKQLENSVVNAYHTSSEKIFTDYLTKLDKEYSHPKM
                     KSDFIKEFRIFLDRFDVEIKKTLSSSDLTMMGIINRYLKYNESINVMLEESDRKEHFN
                     DLFSLLLFLKISIESDIKIDEKNRHILSVNLDKLLFLVLGNDDNFREPSEIIKEFKDL
                     FQRLDDSEKFRIFYSG"
BASE COUNT          329 a           98 c          153 g          295 t
ORIGIN      
        1 tgtttttttc aagatcaaaa aaattttaat atttcaccat tttatccaga ttcggaaagt
       61 agaagtattg aagagacaaa acaaatgatc agtgcttctt ttggttcgaa agttattaat
      121 tacaatgata ataatgagga ttttctggac caagcttttg aaaactttaa tatgagacat
      181 atacctcatg aatcattaga agaaaaggta gtgaggaata taccaataag tttaggtttt
      241 gtgaacaatc aactatcgca agatatgctt gatcacatta tttccgagtt ttttaaatca
      301 tgttacaacc ctgaagatgc gtcggtacaa ttaattagtg gtgaaaggtt aaacaaactc
      361 aaaggaatta taaaaaagca actagaaaac tcagtagtaa atgcatatca tacaagttct
      421 gagaaaattt tcacagatta cttaacaaaa ttggacaaag aatattctca tcctaaaatg
      481 aagtcagatt ttattaagga gtttagaata tttttggata ggtttgatgt tgagataaaa
      541 aagactttgt catctagcga tttaacaatg atgggtatta tcaataggta tttaaaatac
      601 aatgagagta ttaatgtaat gctagaggag agtgaccgta aggaacattt taatgacttg
      661 ttttcattat tgttattcct caagatttcg attgaaagtg atataaagat tgacgagaaa
      721 aacagacaca ttttatcagt taatttagat aaactgctct ttttggtttt aggaaatgac
      781 gataatttta gggagccttc agaaattatt aaagagttta aagatttatt tcagaggtta
      841 gatgattcag aaaaatttag aattttttat tctgg
//
LOCUS       DAVMJI010000109          852 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.111, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000109 DAVMJI010000000
VERSION     DAVMJI010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.111"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            6..227
                     /locus_tag="VYR58_002103"
     CDS             6..227
                     /locus_tag="VYR58_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623175.1"
                     /translation="MKDEENLLIKESIDFYFDNVVSQVIKPELSTDLNTMNTFSFMLG
                     VSGVVYEISRKQDDRLLNVLLLELRGHDD"
     gene            220..>852
                     /locus_tag="VYR58_002104"
     CDS             220..>852
                     /locus_tag="VYR58_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623176.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYL"
BASE COUNT          301 a          106 c          136 g          309 t
ORIGIN      
        1 caatattgaa agatgaagaa aacctattaa taaaagaatc tatagatttt tattttgata
       61 atgtcgtttc tcaggtcatc aaaccagaat taagtacgga tttgaatact atgaatacat
      121 tttcttttat gctaggagta tctggagttg tctatgaaat atctcgaaaa caagatgata
      181 gattacttaa tgttttatta ctggagttaa gaggacatga tgactagaaa agtacctaat
      241 attgagcaaa tgtctcaaat agaatgtggt ttatgttgct gcttgtccat actacatttc
      301 tataaaagca aagagacatt actagattta agacgtgata tagaaaaagg gagagatggt
      361 tatagtatag gtgacttgaa acagttattg aataaacgaa attttgatac tggctcatat
      421 caagttaaag atgtaaataa aattagtgaa cttccgttac cattaatagc attctgggat
      481 aatcaacatt atgtagttat ttacaaagta aaaaagaata aggtctatat aatggatcct
      541 tctaaaggat atataaatta tgagtttaag gagttttcaa aacattttag taatatagta
      601 ctgctatcat ttcctaacga aaattatcaa tctttgaagt cgcagtttcc ttctccatgg
      661 ataagagtat tctctagttt ttcaaaggta aaaggtcgat tgattttgac gttactattt
      721 tcaataataa gttacttaat aatactttcc gtaccagtaa tgacttcaaa gtttattaat
      781 tctgcattag ggaatacatt ttcttttcaa acctcgtttt taattttatt ttctctactt
      841 tgtttgtatc tt
//
LOCUS       DAVMJI010000110          708 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.112, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000110 DAVMJI010000000
VERSION     DAVMJI010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..708
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.112"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            82..558
                     /locus_tag="VYR58_002105"
     CDS             82..558
                     /locus_tag="VYR58_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV3623177.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            596..>708
                     /locus_tag="VYR58_002106"
     CDS             596..>708
                     /locus_tag="VYR58_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV3623178.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAV"
BASE COUNT          244 a          116 c          133 g          215 t
ORIGIN      
        1 aaagaacaaa aagtaattga caacggtttc atatagtgtt atacttatgg cataaagtta
       61 atggaaagaa gggaaaaact tatggtatta gattatttct ttgacaaaaa ccttgtgttt
      121 tgcttagaag cggataatca agaacatctc tttgatcagg ttgcaacttt attggaagaa
      181 cgagaaattg taactccaac ttatcgtgaa gccttgatca cgcgtgaaaa gtcatttcca
      241 actggtttag atatggaatt tctaggaaag gacttgccaa atgtagcgat tcctcacaca
      301 gatattgttc ataatctagc tgagaaagtg gtggttgttc gattagaaaa accagtaact
      361 tttcacaata tgatagctcc tgataaggaa gtagaagtat ctctactctt ctttatcatt
      421 aacaattcaa gttcaagtca aacgaacatt ctggctcagt tgatggactt tttcacagga
      481 aatggtcatc ttgaagacct atcaaaaatt tctgaaccag aaaaacttta tgcttacatt
      541 gctgaagcaa ccgcttaatc ttgtctatta aaaaataaaa tcggaggaaa tccaaatgat
      601 taaaattctt gctgcctgcg gtgcaggtgt taactcaagt caccaaatta aaagtgctct
      661 agaagaagaa ctttcaaacc gtggttatga tgttcactgt gatgcagt
//
LOCUS       DAVMJI010000111          673 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.113, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000111 DAVMJI010000000
VERSION     DAVMJI010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.113"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            83..445
                     /locus_tag="VYR58_002107"
     CDS             83..445
                     /locus_tag="VYR58_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV3623179.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          225 a           83 c          122 g          243 t
ORIGIN      
        1 atctacaacc tcaaaacagt gttttgagca acctgaggct agtttcctag tttgctcttt
       61 ggttttcatt gagtataaca gattgttaga agttggttta aatttcctaa tcagtttgtt
      121 cacatttacc ttcgatatat tatatcccat agttaaggtt ggtcatacag atgattatag
      181 tcatggagcc gtaaaactta gtgtttcttt agttgacaaa gatgccatga aaaaaatatc
      241 tgtaactgta ataggatatt ttgaaataaa tatagatgaa aatatcaccg atattctata
      301 cgtaaatggt actgctattc tttatcatta tttacgttct attgtttcaa tagtttcggc
      361 aattgatagc agtgaagcaa tgttgctacc taccattaat gttttagagt tactagataa
      421 atctcaacct tttgaagaag aataatttat tagctcacta aattgagggt aaggaaaagt
      481 aaaatcagta agaaaaatgt cttgcattat acagcaacct tttgggaatg agtagatgga
      541 ttgaataaaa ttttattaag agtggatgat ttatctgtag attattattg gacagttagt
      601 cttgaagtag tctaagaatt aggttataat cagtagaatc cttgctaata atgaggaggt
      661 tagtttatgt ata
//
LOCUS       DAVMJI010000112          635 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.114, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000112 DAVMJI010000000
VERSION     DAVMJI010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.114"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
BASE COUNT          240 a          113 c           73 g          209 t
ORIGIN      
        1 ttagtatatc caatcactag tccaataatt ggactagcag acatgcttag atataataaa
       61 aataacaaaa aatgaatttc accaattcct gcaaaaaaat gtttcatagc tatagtttta
      121 cgcccataaa tacccatcaa atttaccgtc tacgatatct aaaccatatg caatggctcc
      181 tcctaatgag aagacttcag caacagtagc cgcaatatta agagcattag taatagttgc
      241 catactaact ccaccaatat atcttgttat agcacttagt tacctagata agatatcctt
      301 tagcttgctt ccaaaattta agtctacacc tataatatga gttcatatta gtactgctaa
      361 atcctatcta tagtaatgtc aaacacctaa ataaagtcat ctctccaatt cattcaagaa
      421 atgaagaaag gcaaaaaatc tttaaaataa gaaaagtgca tattatcagg tgttcaaaaa
      481 tattgatgat atacgttata tagatagaaa gatttactca atctcacttt caaattgagt
      541 tttttcccaa cctcgttttt aatttatatc ttcaataaaa tctaatgacc tagttgatat
      601 gtcatatgga ataatattat ttaatctgta atttt
//
LOCUS       DAVMJI010000113          613 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.115, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000113 DAVMJI010000000
VERSION     DAVMJI010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.115"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(30..509)
                     /locus_tag="VYR58_002108"
     CDS             complement(30..509)
                     /locus_tag="VYR58_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV3623180.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          164 a          143 c           79 g          227 t
ORIGIN      
        1 taattttttt catttttttg catgacttac taatgggtac ggatagtaaa ctccttaaac
       61 acaatgcgta agtctcttaa tactctttga cgccctcgaa atcgttcatt gcttaagacg
      121 cgttctagtt cttcttgttt ctctttactt tgtttgtttc tataatctct tagtgtttca
      181 tgaaagagat aataatcatc tagccagaga cccccctcac ttatacgatg actgatctca
      241 cccacttctt catagggttc tttatcgtat ctacgcttct gactttcctg tttacggata
      301 tagtctaaaa ttcgatttcg aaacttggtc ttgaaatatt tccttaaacg tggaatatcg
      361 tctaccagtc cttcttctct actaatcaat tcatgtaagc agagcatgcc ttcttgctcc
      421 caatccgaca attcccataa atgaaggtaa tattcatttc tacacttata cacagtccct
      481 tggacttctt catacaattc tttaatcata attttcccct ttctagatac agtctaacag
      541 attagaaaac acatttgttc cattttctcc attctgttcc ctttagctcc taaactgcac
      601 aaaaaagaga ggc
//
LOCUS       DAVMJI010000114          602 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.116, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000114 DAVMJI010000000
VERSION     DAVMJI010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.116"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..>602
                     /locus_tag="VYR58_002109"
     CDS             <1..>602
                     /locus_tag="VYR58_002109"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HEV3623181.1"
                     /translation="IKNKLSNSNFDGLTFETDKDIQKKIEDLKGQVEKYQYALSHIVN
                     YYNLINDKEQIPKSIDEFNQKNEKLEGEIQVLQDRVVELKSDFSTVESKNDIDSLIQL
                     VQEAYKFVSDHKEFENTCPVCSQSVKNTTKHFDERITNLLEQSNITAEKISGFRKRIN
                     ETESSILNKQEEVRTIQLDISKLKYQENEIQTKLDIILGD"
BASE COUNT          252 a           75 c          105 g          170 t
ORIGIN      
        1 ataaaaaata agttatctaa ttctaacttt gacggattaa cttttgaaac ggataaagat
       61 atacaaaaga agattgagga tttaaagggg caggttgaaa agtatcaata tgctttgtct
      121 catattgtta actattacaa tttaataaac gataaggaac aaattccaaa atctattgac
      181 gagtttaatc aaaaaaatga aaaattagaa ggcgaaatcc aagtattaca agatagggta
      241 gttgaattaa agtcagattt tagcacagtt gaatcaaaga atgatattga ctcactgatt
      301 caattagttc aagaggcata taaatttgtg agtgaccata aggaatttga gaatacttgc
      361 ccggtttgca gtcagtccgt taaaaatacc accaaacatt ttgatgagcg tattactaat
      421 ctattggaac aaagtaacat tacagctgaa aaaattagtg ggtttaggaa acgaataaac
      481 gagactgaat caagcatttt gaataaacaa gaagaagttc gtacaattca attagatata
      541 tccaaattaa aatatcaaga gaacgaaatc cagacaaaac tagacattat attgggtgat
      601 ta
//
LOCUS       DAVMJI010000115          562 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.117, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000115 DAVMJI010000000
VERSION     DAVMJI010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.117"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            21..238
                     /locus_tag="VYR58_002110"
                     /pseudo
     CDS             21..238
                     /locus_tag="VYR58_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT          246 a           58 c           97 g          161 t
ORIGIN      
        1 aagaaaaaaa gagggatatt atggcactta actataaacc attatggata cagttagcaa
       61 aaaaagacta aagaaaacag atgtaataac tatggcagga cttacaacaa atgttatggc
      121 acaaatggga aaggataaac caattacatt taagaattta gaaagaatat gtaaggcttt
      181 atcttgcact cctaatgata ttattagttt tgaagataat tttagtgacg aggaatagaa
      241 aatgacttta aggacagaag atcaagttag ggattatgca agagaagtat aggctttaat
      301 gaagttgaag aaaacatcaa tcaaggtact ggtcaaataa ctacttttaa tcaattaggc
      361 ttcaagggat attcagataa gccagatggt tggtatttac ctaaaaatat gaatgatgta
      421 gcaataatcc ttgaaacaaa atcagaagaa agagatatta gcaaacaaat ttttattgat
      481 gagttaatga aaaatataga cataatttaa ctaaaaataa aaactagatc cttttttgaa
      541 aaaattatat tattaaattt gt
//
LOCUS       DAVMJI010000116          550 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.118, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000116 DAVMJI010000000
VERSION     DAVMJI010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.118"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            38..>550
                     /locus_tag="VYR58_002111"
     CDS             38..>550
                     /locus_tag="VYR58_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV3623182.1"
                     /translation="MTEEKFQKIIQSKDTETLAFILESTPYHLSIDILEDPSQTEISL
                     MTKLVNDYRWAYAESPSDIIVTLFALRYVYHNIKVLLKSKAAIKKDFSKLLIPIGIFD
                     IESLKHLVSSLHSDTLPDFMVREVESIWNEYETFNNIRVLDVGADLAYFKHLKLLSNE
                     LDEVLSQVIVE"
BASE COUNT          193 a           74 c           89 g          194 t
ORIGIN      
        1 aataaatacg acgatttcgg taaaagaaaa cgattttatt acagaagaaa aatttcaaaa
       61 aattatacaa tccaaagata cggagacatt ggcatttatc ttagaatcaa ctccctatca
      121 tttatcgatt gacatcttag aagatcctag tcagacagag atttcgctaa tgacaaaatt
      181 agtcaatgat tatagatggg cctatgctga aagtccgtct gatataattg tgactttatt
      241 tgctttacga tatgtttatc ataatatcaa agttttatta aaatctaagg cggcaattaa
      301 gaaagatttt tctaaattat taattccaat agggattttt gatatagaaa gtttaaaaca
      361 tttagtttct tccttacatt cagatacact tcctgatttt atggttcgtg aagtagaatc
      421 aatttggaat gagtatgaaa cttttaataa tattcgtgta cttgatgtcg gagctgatct
      481 agcatatttt aaacatctga aacttttatc taatgagtta gatgaggtac tgtctcaggt
      541 tattgtcgaa
//
LOCUS       DAVMJI010000117          548 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.119, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000117 DAVMJI010000000
VERSION     DAVMJI010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.119"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..>548
                     /locus_tag="VYR58_002112"
     CDS             <1..>548
                     /locus_tag="VYR58_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3623183.1"
                     /translation="ISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNV
                     FQLFAPIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQYILAAGYL
                     NRVNDIWLENEENVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLTIEPGQRIA
                     LVGQSGSGKSTLSKILSGLYKI"
BASE COUNT          201 a           65 c           97 g          185 t
ORIGIN      
        1 atttcttcaa taaaaatatc gggattagaa gatgaaatat atgaaaactg gtctaagtat
       61 ttaaaaaacg tattgacaaa gtataaaaaa cgaagtattg tgcatatttt atacaattca
      121 gctactaatg tatttcaatt gttcgctcct ataattatat tgatttttgg acttgataat
      181 gttttaaatg gaaaaatttt attgggtgag gttgtcgcat ttcaaaccat ggcatcaatt
      241 ttatttagtt cagaaatctc aatatttaat gcttatacgc agtatatttt ggcagcagga
      301 tacttaaata gagtaaatga tatctggctt gaaaatgaag agaatgttga aaatggtctt
      361 aaaaagtgtt ctttagaagg tagaatagat attaaggacc tatctttctc ttattccaaa
      421 gactcagctc ctgtaataga aaatttaaat ttgactattg agccaggaca gagaattgca
      481 ctagtcggtc aatcggggtc aggaaaaagt acgttatcaa aaatactatc aggattatat
      541 aagattga
//
LOCUS       DAVMJI010000118          499 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.120, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000118 DAVMJI010000000
VERSION     DAVMJI010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.120"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(18..>499)
                     /locus_tag="VYR58_002113"
     CDS             complement(18..>499)
                     /locus_tag="VYR58_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3623184.1"
                     /translation="LYGASLFSFLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLC
                     FSLIHAQGSTNQTNLIGLQHQVPWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVA
                     LTSVLFALVHHPGTILAWCLYVSLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
BASE COUNT          195 a          106 c           69 g          129 t
ORIGIN      
        1 aaatcaggtc acctatttta aaaaagcagc aaactataaa ctaaaaagtt ccacaccaaa
       61 tgtaacccca tacttcccca taagtcagat ttatagcgca ccatacctaa aaacattcca
      121 agtgaaacgt acagacacca agctagaatg gttcctggat gatgtactaa ggcaaataaa
      181 acacttgtca aagcaactcg aatatctaat tttctaacca agttccataa aatttcacga
      241 tacagaaatt cttcaaccat actcgcattg attaagaaca ataaaaatga aaaccaagga
      301 acttgatgtt gaaggccaat taaatttgtt tgattcgtgc ttccttgagc atgaatcagg
      361 ctaaaacata gacttataat cagtagacta gctagtccaa taccaaggca tttcatccta
      421 gttttcatat tgaccttgac cacttgtttt cgttgaccat acatccataa aaaagaaaaa
      481 agagacgcac catagagaa
//
LOCUS       DAVMJI010000119          484 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.122, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000119 DAVMJI010000000
VERSION     DAVMJI010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.122"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            182..>484
                     /locus_tag="VYR58_002114"
     CDS             182..>484
                     /locus_tag="VYR58_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623185.1"
                     /translation="MKKRINKKASVFLVASVFSFSFATTASVVNAVTAHPAPSPIIDV
                     WEYGVNDNYGYSNYFVSSPSNIGSKSSVTNFWGTVKAQDKKDYGWAYSSATKSWNDV"
BASE COUNT          176 a           62 c           90 g          156 t
ORIGIN      
        1 tacatttaga tgtgttcaat tttaaaagga ggggtagtta tgagatattt taacgactct
       61 agataccata acggtgatta aaaacctaaa tataatcaat tcatattaaa gtaatatgga
      121 gggactaaaa agagactatt atttaatctt catcaaatat ttaaattcaa ggagaagtaa
      181 aatgaaaaaa agaattaata agaaagcatc tgtttttcta gttgcaagtg ttttcagttt
      241 tagctttgct actacagcta gtgtcgttaa cgcagtaacg gcacaccctg ctccaagtcc
      301 cattattgat gtatgggaat atggtgtaaa tgataactat ggttattcga attactttgt
      361 tagttctcca agtaatattg gatcaaaatc ttcagtaacg aatttttggg gaacagttaa
      421 agctcaggat aaaaaagatt atggatgggc atattcaagt gcaacaaaat cttggaacga
      481 tgtt
//
LOCUS       DAVMJI010000120          482 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.123, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000120 DAVMJI010000000
VERSION     DAVMJI010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.123"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(146..433)
                     /locus_tag="VYR58_002115"
                     /pseudo
     CDS             complement(146..433)
                     /locus_tag="VYR58_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          163 a           88 c           82 g          149 t
ORIGIN      
        1 ggttaggaga gaaatataat gatttttgaa aattgattca aaaaatagcg aattgtagaa
       61 aacgcttaac aaatggtgta taatagactt ccagcgaaac aaaatatgct acaataaacc
      121 tatgaattat aaagcaacct tatactcatc tgtcttcaca aagcattcta gtccatctcc
      181 gattaacgat ggactttatc atctccttct ccagtccttg tatgacatct tccaaagttc
      241 gaaaggcttt attcttaaat ccacgtttac gaatctcttt ccacacttat tcaatggggt
      301 tcatctctgg tgtgtatgga ggaataaatg caaagccaat attagtcgga atctttaagg
      361 cacttgattt atgccatata gcattgtcca taacgagtaa aatataatca tctggataag
      421 cttgtgaaag tttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
      481 aa
//
LOCUS       DAVMJI010000121          431 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.125, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000121 DAVMJI010000000
VERSION     DAVMJI010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.125"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..>431
                     /locus_tag="VYR58_002116"
     CDS             <1..>431
                     /locus_tag="VYR58_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV3623186.1"
                     /translation="KSIYWNFGQNKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQA
                     PSRARKLVSQNSVLFSTVRPYLKNIAIVRELKEYLIASTAFIVLDTLLNETYLKYYLL
                     SDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLSEQQRI"
BASE COUNT          163 a           68 c           55 g          145 t
ORIGIN      
        1 taaaatcaat ttattggaat tttgggcaaa ataagccaga gaaatccttt aggtatatag
       61 atacgtctag tattgataga aaaaagaaca taatcaacta caaaaatcta caatatcttt
      121 cacctgaaca agcgccttcc cgtgctagaa aattagtttc gcagaatagt gtcttatttt
      181 caacagttag accatatcta aaaaatattg ctatagttag agaacttaaa gagtatttga
      241 tagctagtac agcatttatt gttttggata ctttacttaa cgaaacatat ttgaaatatt
      301 atttattatc agataatttt atcaatcgtg ttaataataa atctactgga acaagttatc
      361 ctgcaatcaa tgattataat tttaatctat tattaattgc tctcccccca ctatccgaac
      421 aacaacgaat a
//
LOCUS       DAVMJI010000122          412 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.126, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000122 DAVMJI010000000
VERSION     DAVMJI010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.126"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..>412
                     /locus_tag="VYR58_002117"
     CDS             <1..>412
                     /locus_tag="VYR58_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nickase"
                     /protein_id="HEV3623187.1"
                     /translation="ERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKTNKEKYD
                     FKKLTSAYSYLRKNNIETIGQLQTKIETLKSNSYRLNKKAKTIHKEMEDVEKKILYYE
                     IYKAKKEVYEEYQKKNIFTKEAFYNKHKKDIDQYK"
BASE COUNT          221 a           48 c           49 g           94 t
ORIGIN      
        1 cgaaagagat aaggtaatag acaaccctaa actttttaat ctaacaaatt atctattaac
       61 ttattcagaa attcaaaaag aaaaaagtaa atatctaaaa ggatatgcaa aaactaataa
      121 agaaaaatat gacttcaaaa agctaacaag tgcatatagt tatttaagaa aaaacaacat
      181 agaaaccata ggtcagttac aaacaaaaat agaaacttta aagtctaata gttataggct
      241 aaataaaaaa gcaaagacaa tccataaaga aatggaagat gtagaaaaga aaattctata
      301 ctatgaaatc tacaaagcca aaaaagaagt ttatgaagaa tatcaaaaga aaaatatatt
      361 cacaaaagaa gcattttata acaaacataa gaaagatata gaccaatata aa
//
LOCUS       DAVMJI010000123          371 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.128, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000123 DAVMJI010000000
VERSION     DAVMJI010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.128"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            complement(<1..348)
                     /locus_tag="VYR58_002118"
     CDS             complement(<1..348)
                     /locus_tag="VYR58_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV3623188.1"
                     /translation="MNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTII
                     SEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKSQGCTQII
                     VAHRLSTIKDADII"
BASE COUNT          111 a           71 c           51 g          138 t
ORIGIN      
        1 aataatatcc gcatccttaa tcgttgacaa tctatgagct acaattattt gagtacagcc
       61 ctgacttttt atatactttg ttattctttc ctcattaata gtgtctaaag cactagttgc
      121 ttcatctaaa attacaatac taggattatt tattaatgca cgtgccagtg ctatccgttg
      181 tctttgacca cctgaaatat ttgaacccat ctctgagatg atagtattaa atttcatcgg
      241 catagccatg atttcatcat agatttgaac tgctttacaa acttcctcta tcttttgtga
      301 agtaacttcg tgctttaaag ttatgttatc aagaatactt ctgttcaata aaaacgaatc
      361 ctgtggaact a
//
LOCUS       DAVMJI010000124          364 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.denovo.129, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000124 DAVMJI010000000
VERSION     DAVMJI010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.denovo.129"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            <1..>364
                     /locus_tag="VYR58_002119"
     CDS             <1..>364
                     /locus_tag="VYR58_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV3623189.1"
                     /translation="DDILAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDG
                     YIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQD
                     SGNTEAKGAEAIYNRVKAA"
BASE COUNT          117 a           79 c           85 g           83 t
ORIGIN      
        1 tggatgatat tcttgccttc ttagctccga ttcgtcatcc agaacgttta ggaaaaccaa
       61 atgcgcaaat tacctacact gatgatgaga ttcaagtagc caagttggca ggcaagtaca
      121 caacagaaga cggttatatc tttgatcctc gtgatataac cagtgatgag ggggatgcct
      181 atgtaactcc acatatgacc catagccact ggattaaaaa agatagtttg tctgaagctg
      241 agagagcggc agcccaggct tatgctaaag agaaaggttt gacccctcct tcgacagacc
      301 atcaggattc aggaaatact gaggcaaaag gagcagaagc tatctacaac cgcgtgaaag
      361 cagc
//
LOCUS       DAVMJI010000125        15200 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.guided.042, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000125 DAVMJI010000000
VERSION     DAVMJI010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15200
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.guided.042"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            555..869
                     /locus_tag="VYR58_002120"
     CDS             555..869
                     /locus_tag="VYR58_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV3623190.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            885..1271
                     /locus_tag="VYR58_002121"
     CDS             885..1271
                     /locus_tag="VYR58_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV3623191.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1300..2685
                     /locus_tag="VYR58_002122"
     CDS             1300..2685
                     /locus_tag="VYR58_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV3623192.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2688..2840
                     /locus_tag="VYR58_002123"
     CDS             2688..2840
                     /locus_tag="VYR58_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV3623193.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2863..4281
                     /locus_tag="VYR58_002124"
     CDS             2863..4281
                     /locus_tag="VYR58_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEV3623194.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKKGYLSTIPVDRYPKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMEI
                     RLRSKLKSVLIVHYLKILYNRN"
     gene            4330..4413
                     /locus_tag="VYR58_002125"
     CDS             4330..4413
                     /locus_tag="VYR58_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEV3623195.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            4538..5275
                     /gene="erm(B)"
                     /locus_tag="VYR58_002126"
     CDS             4538..5275
                     /gene="erm(B)"
                     /locus_tag="VYR58_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEV3623196.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(5532..6779)
                     /locus_tag="VYR58_002127"
     CDS             complement(5532..6779)
                     /locus_tag="VYR58_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV3623197.1"
                     /translation="MSHNDSILNILGIKDKNIKIISVEEAEHNNDSVKEYITLITATL
                     SYPINRCRNCGFPTVNKDGFRKTHVRLASLNGRRYELELRKQRYKCKSCHTTFGAITN
                     LTKENQTLSSDLKNQIMLLARKGLSGQLIAEMCHCSPSSVRRTILERMEPHYRVAKLP
                     KHLCFDEFRSIKSVMSFICCDAETHQIVTKLQDRLSPTIVDYFESRYSKAERECVQSV
                     VIDLNAQYQSFIYRLFPNANIIIDRFHLVQLAGRALDNCRISILKQLDKQSQEYKIMK
                     SHWKLFHKKAEDLHPEEVVFLRGVKQYMTRQNAVDLITSKFSKFAEVYQTYQDITKAL
                     NERNSELLESTILDYQKTNTEMDTAIQTLRQNRKYVLNSAKFEYSNGPLEGINRKIKT
                     LKRTCYGFANQKFFFLRIDCIFS"
     gene            6959..7180
                     /locus_tag="VYR58_002128"
     CDS             6959..7180
                     /locus_tag="VYR58_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV3623198.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            7297..7794
                     /locus_tag="VYR58_002129"
     CDS             7297..7794
                     /locus_tag="VYR58_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEV3623199.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            7769..8275
                     /locus_tag="VYR58_002130"
     CDS             7769..8275
                     /locus_tag="VYR58_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV3623200.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            8259..10706
                     /locus_tag="VYR58_002131"
     CDS             8259..10706
                     /locus_tag="VYR58_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV3623201.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            10709..12886
                     /locus_tag="VYR58_002132"
     CDS             10709..12886
                     /locus_tag="VYR58_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV3623202.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            12883..13884
                     /locus_tag="VYR58_002133"
     CDS             12883..13884
                     /locus_tag="VYR58_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEV3623203.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            13881..14816
                     /locus_tag="VYR58_002134"
     CDS             13881..14816
                     /locus_tag="VYR58_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV3623204.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            15061..15177
                     /locus_tag="VYR58_002135"
     CDS             15061..15177
                     /locus_tag="VYR58_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEV3623205.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
BASE COUNT         4919 a         2762 c         3137 g         4382 t
ORIGIN      
        1 cagtccctac ttacacaggc acgctaatca agacggagtg gattcaattt tcaaagaaca
       61 ggtagcttta ttatagagaa gagtagttga aatttttatc acatttttta tttttctgta
      121 gagctaaatt catactaaac aaagattttg aaataaaaga ctaacattgt tacataacgt
      181 tagcatttca tttccctaaa ataagctaat tttgtctaaa aaatagcata aaaatctagt
      241 tatccgcata aaaactggac ttatcacact ttatcaaggt caaaaccact caatttacta
      301 ctaatttact acttatgaat gagctttgat acgacgattt atccttgaaa agtgaagata
      361 taaagatact tccaataaaa tttgaatatt taataggtag acacttcaaa aaatgaggtg
      421 tctatttttt tacccgattt tgaaaggaag tgaacttatg aaaacaaaaa atcaagaatc
      481 aaaaggtcgt tccccactct ttaagaccat caaacattca ttcagccaat aaaaaagaaa
      541 ggataggtaa aaatatggaa cttaaatttg tgattcccaa catggaaaaa acattcggca
      601 atttagaatt tgctggcgag gataaagtcg ttcagcgaag aatcaacgga cggctaactg
      661 tcttatcaag aagctataat ctctattctg atgttcaaag agcagatgat attgtggtgg
      721 tgcttcctgc tgaagctggc gaaaaacatt tcggctttga ggaacgtgtg aagttagtca
      781 atccacgtat taccgcagag ggctacaaaa tcggcactcg tggttttaca aattaccttt
      841 tacatgctga cgacatgata aaagaataaa gaaagagagg aaaaatgatg agattagcaa
      901 atggcattgt attagataaa gacacgactt ttggagaatt gaaattctct gctctacgtc
      961 gtgaagtgag aatccaaaat gaagacgggt cggtttcaga tgaaatcaag gaacgtacct
     1021 atgacttaaa atccaaagga caaggacgca tgattcaagt aagtattcct gccagcgtgc
     1081 ctttgaaaga gtttgattat aacgcacggg tggaacttat caatcccatt gcggacaccg
     1141 ttgctactgc cacctatcaa ggagcagatg ttgactggta tatcaaggca gacgatattg
     1201 tgctgacaaa ggattctagt tcattcaaag ctcaaccaca agcaaagaaa gaaccgacac
     1261 aagacaaata gtcgctaggt agaaaggaga ctttttcgca tgaaacagcg tggtaaaagg
     1321 attcgcccat ctggtaaaga tttagtcttt cattttacga tagcgtcact cctgcctgtt
     1381 ttcctgctgg ttgtcggact gtttcatgtg aagacaatcc agcagatcaa ctggcaggat
     1441 tttaacctat cacaagcaga taagattgac attccctatt taattatcag tttcagtgtc
     1501 gcaattctta tctgcttgct ggtagcgttt gtattcaaac gggttcgcta tgatacggtt
     1561 aaacaacttt accaccgtca aaaactggca aagatgatac ttgaaaacaa gtggtatgaa
     1621 tctgaacagg tcaaaacaga gggtttcttt aaagatagtg ctggtcgtac aaaggaaaag
     1681 ataacctact tccctaaaat gtattatcga cttaaaaatg gcttgataca gatacgggtg
     1741 gaaatcacgc tgggaaaata tcaagaccaa ctcttacact tggaaaagaa attagagagt
     1801 ggcttgtact gtgagctgac ggataaagag ttaaaggatt cctatgtgga atatactttg
     1861 ctctatgaca ccatagccag tcgtatttct attgatgaag tagaagctaa agatggtaaa
     1921 cttcgcttaa tgaaaaacgt atggtgggaa tatgataagc tccctcatat gttgattgct
     1981 ggtggtacag gtggcggtaa aacttacttt atactgacac tgattgaagc cttgcttcat
     2041 acagattcaa aactgtatat tcttgacccg aaaaatgctg atcttgcgga cttaggttct
     2101 gtgatggcaa atgtctacta tagaaaagaa gacttgcttt cttgcattga aacattctat
     2161 gaagaaatga tgaaacgtag tgaggaaatg aagcagatga agaactataa gactggcaaa
     2221 aattatgctt acttaggtct cccggcacac ttcttaatct ttgatgaata cgtcgctttc
     2281 atggaaatgc tgggaacaaa agaaaacacc gcagttatga ataagctgaa acagattgtc
     2341 atgttaggtc gtcaagctgg cttctttcta atactggctt gtcaacgtcc agacgcaaaa
     2401 tatttaggcg acggaatccg tgatcagttt aatttcagag tggctttagg tcgtatgtct
     2461 gaaatgggct atggcatgat gtttggcagt gacgtacaaa aggatttctt cttaaagcga
     2521 atcaaaggtc gtggctatgt tgatgtagga acaagtgtca tatcagagtt ttatactccc
     2581 cttgtaccaa aaggatatga tttcttggag gaaattaaaa agttatccaa cagcagacag
     2641 tccacgcagg cgacgtgcga agcggaagtc gcaggtgtgg actgatcttg ctggctggtg
     2701 tggcaatagc cacgccagca cttaaccccc cgtatctaac aggggggtac aaatcgacag
     2761 gaaacagtca aaaaaacatt agaaaatcct ttggttacaa gggatttaca aaatttcagc
     2821 gtatgtcaaa tgggctttaa aagttgacat acgccttttt gattggaggg atttttactg
     2881 aatgaacaaa cttggttaca gcatttaaaa gaaaaacgct tggcttatgg actatctcaa
     2941 aaccgtttag ctgttgcgac tggtattaca aggcagtatc taagcgatat tgaaacagga
     3001 aaagtcaagc catcagagga tttacagcag tccctttggg aagctctgga acgcttcaat
     3061 cccgacgctc cccttgaaat gctgtttgat tatgtaagaa ttcgctttcc gacaacagac
     3121 gtacagcagg tggtcgaaaa catcttacaa ctgaaactgt cctattttct tcatgaggac
     3181 tatggtttct attcttattc agagcattat gctttaggcg acatattcgt cctttgctcc
     3241 catgaactgg acaaaggagt tctggtggaa ttgaaaggtc gtgggtgcag acaatttgaa
     3301 agctatcttc tggcacaaca aagaagctgg tatgagttct ttatggacgt tttggtggct
     3361 ggcggtgtga tgaaacgcct tgaccttgcc attaacgata agacagggat tttaaatatc
     3421 cctgtactca ctgaaaagtg ccaacaggaa gaatgtatct ccgtcttccg cagttttaaa
     3481 agctatcgca gtggcgaact ggtacgcaaa gaggaaaagg aatgtatggg aaacaccctc
     3541 tatatcggtt cattacaaag tgaagtttat ttctgtatct atgaaaagga ctacgagcag
     3601 tacaagaaaa atgatattcc cattgaagac gcagaagtaa aaaaccgttt tgagattcga
     3661 ttgaaaaatg agcgtgccta ttatgcagtc cgtgatttac tcgtctatga caatccagag
     3721 cataccgcct ttaaaattat caatcggtat atccgttttg tagataaaga cgattccaaa
     3781 cctcgttctg attggaaact gaatgaagaa tgggcttggt ttattgggaa caatcgtgaa
     3841 cgattaaaac taaccacaaa accagagcct tactccttcc aaaggacgct gaactggcta
     3901 tctcatcaag ttgccccgac cttaaaggtt gcgattaaac ttgatgaaat caaccagacg
     3961 caggttgtaa aagacattct cgaccatgcg aaactgacag accgacacaa gcagattttg
     4021 aagcaacagt cagtaaaaga acaggacgtg ataacaacaa aaaaaggata tctgtcaacc
     4081 ataccagttg acagatatcc aaaaaaagat ataatgggag ataagacggt tcgtgttcgt
     4141 gctgacttgc accatatcat aaaaatcgaa acagcaaaga atggcggaaa cgtaaaagaa
     4201 gttatggaaa taagacttag aagcaaactt aagagtgtgt tgatagtgca ttatcttaaa
     4261 attttgtata ataggaattg aagttaaatt agatgctaaa aatttgtaat taagaaggag
     4321 ggattcgtca tgttggtatt ccaaatgcgt aatgtagata aaacatctac tgttttgaaa
     4381 cagactaaaa acagtgatta cgcagataaa taaatacgtt agattaattc ctaccagtga
     4441 ctaatcttat gactttttaa acagataact aaaattacaa acaaatcgtt taacttctgt
     4501 atttgtttat agatgtaatc acttcaggag agattacatg aacaaaaata taaaatattc
     4561 tcaaaacttt ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa
     4621 agaaaccgat accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc
     4681 taaaataagt aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc
     4741 agaaaaatta aaactgaata ctcgtgtcac tttaattcac caagatattc tacagtttca
     4801 attccctaac aaacagaggt ataaaattgt tgggaatatt ccttaccatt taagcacaca
     4861 aattattaaa aaagtggttt ttgaaagccg tgcgtctgac atctatctga ttgttgaaga
     4921 aggattctac aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca
     4981 agtctcgatt cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt
     5041 aaacagtgtc ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa
     5101 gctatatacg tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa
     5161 aaatcagttt catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccattactta
     5221 tgagcaagta ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta
     5281 tgagtcgctt ttttaaattt ggaaagttac acgttactaa agggaatgga gataaattat
     5341 tagatatact actgacagct tccaagaagc taaagaggtc cctagcgcct acggggaatt
     5401 tgtatcgata aggggtacaa attcccacta agcgctcggg accccttgta ggaaaatgtc
     5461 ctaagtggga tatctgtcaa ctggtatggt tgactaaaaa tacttcctac gaaaatgtag
     5521 ggggtatttt tttacgaaaa aatacaatcg attcttaaaa agaaaaattt ttgattggca
     5581 aaaccataac aagttcgttt tagggttttg attttgcgat tgatgccttc taaaggacca
     5641 ttagagtatt caaatttagc gctatttaag acatattttc tgttttgacg aagggtttga
     5701 atagcagtat ccatttctgt attggttttt tggtagtcta agatggttga ctctagtaat
     5761 tcactattgc gctcgtttag ggctttcgtg atatcttggt aagtttggta tacttcagcg
     5821 aacttggaaa atttactagt aatgagatca acagcatttt ggcgagtcat atattgttta
     5881 acgccgcgaa gaaaaactac ttcttcaggg tgaagatctt cagctttttt atggaatagc
     5941 ttccaatgtg acttcataat tttatattct tggctctgtt tatcaagttg ctttaggata
     6001 gagatacgac aattgtccaa agcgcgacca gctaattgta caaggtggaa gcgatcaata
     6061 atgatattgg cattagggaa aaggcgatag ataaaacttt gatattgagc atttaaatca
     6121 attacaactg attgaacgca ttcgcgttcg gcttttgaat aacgactttc aaaataatca
     6181 acaatggtag gtgatagacg atcctgtaac tttgtgacaa tttggtgggt ttcagcgtca
     6241 caacagataa aggacatcac agacttaatt gaacgaaact cgtcaaaaca tagatgctta
     6301 ggcaacttag ccacacgata gtgtggttcc atgcgctcta agattgttcg acgaacactg
     6361 ctaggagagc agtgacacat ttcagcaata agctgaccag ataagccttt acgagctaaa
     6421 agcatgattt gatttttgag atcactggat aaggtttgat tttctttggt taaattagta
     6481 atagcaccaa aagtagtatg gcatgattta catttatagc gttgtttacg aagctctagt
     6541 tcatatcttc tcccatttaa acttgccagt cgtacatgag ttttgcgaaa gccatcctta
     6601 ttaactgtgg gaaagccaca gttacgacaa cgattaatcg gataagaaag agtagctgtt
     6661 attagcgtta tatactcttt aacagaatcg ttgttgtgtt cagcttcttc aacagaaata
     6721 attttaatat ttttatcttt aattccaaga atatttagga tagaatcatt atgggacatt
     6781 tgtttaacct tctttcatga tttttgtggt gaattgattg tataacgagg ggacagcaaa
     6841 tgtcctcttt tttgtataaa aaaatctggc atggaatctc tatccatacc agaaagtgta
     6901 taccccaaaa aaataactca aatacaaatt cattgaatat agagaggaga acatttttat
     6961 gaattttgga caaaaccttt ataactggtt tctatcaaac gctcaatcac tggtgctttt
     7021 agcaatcgtt gtgattggct tgtatcttgg cttcaagcgt gagtttagca aactgattgg
     7081 ctttttaatt attgcgatta ttgcggttgg cttagtcttc aacgctgctg gagtaaaaga
     7141 cattttacta gagctattca atcgcattat tggtgcttaa ataaaaccgt tcttttgtgg
     7201 aatataagtg gttttcttat gttccgcaaa ggaatggtac accaaacgaa gtgcggtagg
     7261 gatttttgaa tctctacaaa gaaaggacgt gaatatatgg acgatatgca agtctatatt
     7321 gcgaatttag gcaaatacaa tgagggcgaa ttggtcggtg cgtggtttac ctttcccatt
     7381 gactttgagg aagtcaaaga gaaaatcggc ttgaatgatg aatatgagga atacgccatt
     7441 catgactacg agttaccctt tacggttgac gaatacactt ccattggcga actcaatcga
     7501 ctatgggaaa tggtatcgga attacccgaa gaattacaat cggagctatc tgctctgctc
     7561 actcattttt caagcattga agaactaagc gaacatcaag aggatattat cattcattcc
     7621 gattgtgatg atatgtatga cgtggcacgc tactacattg aagaaacggg tgctttaggc
     7681 gaagtaccag ctagtcttca aaactatatt gattatcaag cctatggtcg ggatttagac
     7741 ctttcaggaa cgtttatctc aaccaatcat gggatttttg aaatcgtcta ttaaatctgt
     7801 cggtacatta ctactggcag attttctatt ttacggggtg gctcaatcag ctacccctat
     7861 tttttatgaa aggattgatt acatgaagaa aatacgaagc tataccagta tctggtctgt
     7921 ggaaaaggta ctgtattcta tcaatgattt tagacttccg tttcccataa cctttacgca
     7981 aatgacatgg tttgtcgtgt cactctttgc agtgatgata cttggcaact tgccccctct
     8041 ttccatgata gagggagcat ttctcaaata ctttgggatt cctgtggctt tcacatggtt
     8101 tatgtctaca aaaacttttg atggtaaaaa gccttatgga tttttgaagt ctgtcattgc
     8161 ttatgcactg cgaccaaagc tgacctatgc aggaaaaaaa gtaacgcttg gcagaaacca
     8221 gccacaagaa gccattacag cagttaggag tgaattttat ggcatatcca attaaataca
     8281 ttgaaaacaa tctcgtctgg aataaagacg gggaatgtta tgcttactat gagcttgttc
     8341 cttacaatta ctcatttcta agtccagaac agaaaataca agtgcatgat tctttcagac
     8401 agcttatcgc acaaaatcgt gatggcaaaa ttcatgcttt acaaatcagt acagaatcca
     8461 gcatacgttc tgcacaagag cgttccaaaa atgaagtcac tggcaagctc aaagcggttg
     8521 cctatgacaa aatcgaccaa cagacagacg ctttaatatc catgattggc gaaaatcaag
     8581 tgaactaccg tttctttatc ggctttaagt tgcttctcaa cgatcaggag ttttctatga
     8641 aaagtcttac cgttgaagca aaaaatgctt tgtctgattt tgtctatgat gtgaaccata
     8701 agctgatggg cgattttgtt agtatgagta atgatgaaat cctgcgtttt cagaagatgg
     8761 aaaagctctt agaaaataaa atctctcgtc gtttcaaaat ccgcaggtta gataaggacg
     8821 acttcggcta tctgattgaa cacctttacg gacagacagg cactgcctat gaagagtatg
     8881 agtaccatct atcaaagaaa aagctggata atgaaacgct gattaaatac tatgacttga
     8941 ttaagcctac tcgctgtttg gtggaagaaa aacagcgata tttgaaaatc cagcaggaag
     9001 atgaaaccgt ctatgtagct tactttacca ttaacagcat tgtcggagaa ctggacttcc
     9061 cgtcctctga aatcttctac taccagcaac agcaatttac attcccgatt gatacgtcaa
     9121 tgaatgtgga aattgtagcg aatcgtaaag ccctatctac tgtccgcaat aaaaagaaag
     9181 aactgaaaga cttggataac cacgcttggc aaagtgataa tgaaaccagc tccaatgtgg
     9241 cggaagctct ggaaagtgtg aatgagctgg aaaccaattt agaccaaagc aaggaatcta
     9301 tgtacaagct gtcttatgtg gtaagggtat cagcaaatga tcttgacgaa ctcaaacgtc
     9361 gttgtaatga agtgaaagat ttttatgacg atttaagcgt aaaactggta cgaccatttg
     9421 gggatatgct cggcttacat gaagaatttt tacctgccag caagcgttat atgaatgatt
     9481 atattcaata cgtgacctct gatttcctcg ctggtttagg ttttggtgct actcaaatgc
     9541 tgggggaaaa tgaggggatt tatgttggct acagcttaga tactggacgc aatgtctatc
     9601 tgaaacctgc tcttgccagt caaggggtta agggttcagt aaccaatgcg ttagcgtcgg
     9661 cttttgttgg ttcgctgggt ggtggtaaat cctttgcgaa taaccttatc gtctattatg
     9721 cggtgcttta tggggcacaa gcagtgattg tagacccaaa agcagaacgt ggcagatgga
     9781 aagaaacctt gccagagatt tcccatgaaa tcaatatcgt cactctgact tctgatgaga
     9841 aaaacaaagg cttacttgac ccttatgtga ttatgaaaaa tcccaaagat tctgaatcac
     9901 tggctattga tattctgaca ttccttacgg ggatttcctc tcgtgatggg gaacgcttcc
     9961 caatccttag aaaagccatt cgtgcagtaa ccaatagtga agtacgaggg ttgatgaaag
    10021 tgattgagga attacgggtt gagaatacgc cactaagtac cagtatagcc gaccatatcg
    10081 aaagttttac agactatgac tttgcacatt tattattcag taatggttat gtggagcagt
    10141 ctatcagctt agaaaaacaa ctgaacatta tacaggttgc ggacttggta cttcccgaca
    10201 aggaaacttc ctttgaggaa tataccacta tggagctttt atccgttgct atgctgattg
    10261 tcattagtac ctttgcttta gactttatcc atacagaccg aagcattttc aagattgtag
    10321 atttagacga agcatggagc tttttacagg tagcacaagg aaaaacacta tctatgaagc
    10381 tggttcgggc tggtcgtgct atgaacgctg gggtatattt cgtgacccaa aatacagacg
    10441 acctcttaga tgaaaaactg aaaaataacc tcggcttaaa atttgcattt cgttccactg
    10501 accttaacga gattaaaaag accttagcct tttttggtgt agacccagag gacgaaaaca
    10561 atcagaagcg attgcgtgat ttggaaaacg ggcaatgcct tatcagtgat ttatatggtc
    10621 gtgtcggtgt gatacagttc caccctgtat ttgaagaact gctccatgcc tttgatacca
    10681 gaccacctgt gcgaaaagag gtgtaaatgt gaaaccatca atagtaaaca gaataaaatc
    10741 aaactggacg ctgaaacgtc taggtaaagt ggcaatgaca gtggctttca cacttgtgat
    10801 tgccattttt cttttagcca tgctgggaac ggtggttcaa gctgcgggct tggtagatga
    10861 tacggtcaat gtggcaaatg aatacagccg atacccactt gaaaactatc aactggattt
    10921 ttatgtggat aatagctggg gctggcttcc gtggaactgg tcggacggga ttggaaaaca
    10981 ggtcatgtat ggactatatg ccattaccaa ttttatttgg acaatcagtt tgtatgtttc
    11041 caatgcgaca ggttacttag tacaggaagc ctattcctta gacttcattt ccgctacagc
    11101 agattccatt ggtaagaata tgcagacctt agctggtgtg agtgcaaacg gattttcaac
    11161 agagggtttc tatgttggat tcctcttact cttgattttg gttcttgggg tttatgttgc
    11221 ctatacggga ctgataaaga gagaaaccac aaaggcaatt catgccatta tgaattttgt
    11281 gctggtgttt atcctatcgg cttcctttat tgcctacgct cccgactaca ttaaaaaaat
    11341 caatgacttt tcatcagaca tcagtaatgc cagtttatca cttggcacga agattgtcat
    11401 gccccattcc gatagtcaag gcaaggacag cgtggactta atcagagata gcctgttttc
    11461 catacaggtt cagcaaccgt ggctactgct tcaatacaac agttcagaca ttgaaagtat
    11521 cggtattgac cgtgtggaaa gcctgctctc caccagccca gattccaaca atggcgaaga
    11581 cagagaaaaa attgttgcgg aagaaattga agacagaagc aataccaatc taaccattac
    11641 aaagaccatt aaccgtttag gtacagtctt cttcctattt gtcttcaata ttgggatttc
    11701 catatttgta ttcctattaa caggaatcat gattttctcg caggtacttt ttatcatcta
    11761 tgctatgttt ctgcctgtga gctttatttt aagcatgatt ccatcatttg atggtatgtc
    11821 aaaacgagcc ataacaaagc tctttaatac cattttgaca cgagctggaa tcacattgat
    11881 tattacgaca gcatttagta tttcaaccat gctctatacc ttatcggctg gttatccgtt
    11941 ctttttgatt gcttttctac agattgtgac ctttgcagga atctacttca agctgggcga
    12001 tttaatgagt atgttttctc tacagagtaa cgattctcaa agtgtgggaa gtcgtgtgat
    12061 gagaaaacct cgtatgctta tgcacgctca catgcaccgt ctacagcgga aacttggacg
    12121 ttccatgact actctagggg ctgggtctgc cattgttaca ggtaaaaaag gacagtcggg
    12181 ttcggggagt tctgcaagga cacaagcaga tcactcccga ccagacggaa aggaaaaatc
    12241 aacacttgga aaacgtatcg gtcaaaccat cggtacagta gctgatacca aagacagaat
    12301 ggtagacact gctagtggtt tgaaagaaca ggttaaagat ttgccgacca atgcaagata
    12361 tgcagtatat caaggaaaat ccaaagtaaa agagaatgtc cgtgatttaa ccagtagtat
    12421 ttctcaaacc aaagcggaca gagccagtgg acgcaaggaa cagcaggaac aaaggcgaaa
    12481 aaccattgcg aagcgtcgct ctgaaatgga acaggtcaaa cagaaaaaac agcctgcttc
    12541 ttctgttcat gaaagaccga ctacaagaca agaacaatat catgatgaac agacctcaaa
    12601 acagtctaat attcagactt catataagga atctcaacaa gccaaacaag agcgtccagc
    12661 agttaagtcc gatttttcaa gtccaaaagt ggaacgccaa ggcaataccg ttcaagaaaa
    12721 aaccgttcaa aagccagcaa cttcaaccac tacagcagat agaacttcac aacgtccaat
    12781 cacaaaagaa cgtccgtcta ctgttcaaag agtaccacta caaaatacaa gaagtagacc
    12841 accaatcaaa accgccacca ttaagaaagt cggtaagaaa ccatgaagtt gaaaacttta
    12901 gtgattggtg gttctggatt attcttgatg gtcttctcac tgcttctgtt tgttgccatt
    12961 ttattttcag atgaacagga cagcggaatt tccaatattc attatggagg tgtgaatgtt
    13021 tccgcagaag tgctggctca taagcctatg gtagaaaaat atgccaaaga atatggcgtt
    13081 gaagaatatg tcaacatact tcttgcgatt atacaggtgg aatcgggcgg tactgcggaa
    13141 gatgttatgc agtcctcgga atccctcggt cttccaccta attcattgag tacagaagaa
    13201 tccattaagc aaggtgtgaa gtatttcagt gaattattag ccagtagcga aaggctcagt
    13261 gtagatttag aatcggttat ccagtcctac aattatggtg gtggtttctt agggtatgtg
    13321 gctaatcgtg gaaataaata tacctttgaa ctggctcaaa gtttctcaaa agagtattca
    13381 ggtggcgaaa aagtgtctta ccccaatccc atagccatac ctatcaatgg gggctggcga
    13441 tacaactatg gcaatatgtt ttatgtgcaa ctggtaacgc agtatcttgt cacaacagag
    13501 tttgatgatg atacggtaca agccatcatg gacgaagcac tgaaatatga gggctggcga
    13561 tacgtttacg gtggagcttc cccgactact tcttttgatt gtagcggact gacacaatgg
    13621 acgtatggaa aagctggaat taacttacca cgaaccgcac aacagcaata tgatgtgacc
    13681 cagcatatcc cactatcgga agcacaagct ggcgatttgg ttttctttca ttctacctat
    13741 aacgctggct cttatattac tcatgttggg atataccttg gcaataaccg tatgtttcat
    13801 gcaggcgacc caatcggtta tgccgactta acaagcccct actggcaaca gcatttagtg
    13861 ggagcaggac gaatcaaaca atgagaaagg aagatttaat gatgaaattt agaaaaaatc
    13921 agaataaaga aaaacagata ccaaaggaaa agaaacctcg tgtctactat aaggtcaatc
    13981 ctcataaaaa ggttgtgatt gccttgtggg tacttttagg gcttagtttc agctttgcga
    14041 tattcaagca ctttacagct atagatactc atactattca cgaaacaact atcatagaaa
    14101 aggaatacgt tgatactcat catgtagaaa attttgtaga gaactttgcg aaagtctact
    14161 attcatggga gcaatccgat aagtccattg ataatcgaat ggaaagtcta aaaggctatc
    14221 tgacagatga acttcaagct ctcaatgttg atacagtacg caaagatatt cctgtatcgt
    14281 cttctgtaag aggatttcag atatggacgg tagagccaac tggcgacaat gagtttaatg
    14341 taacctacag tgtagaccag ctcattacag agggagaaaa tacaaagacc gtccactctg
    14401 cttatatagt gagtgtctat gtagatggtt ctggaaatat ggtactggtt aagaatccga
    14461 ccattaccaa catacctaag aaatcaagtt ataaaccaaa agccattgaa agtgagggga
    14521 cggttgattc cattacaacc aatgaaatca atgagttttt aacgacgttc ttcaagctct
    14581 atcctacagc gacagccagt gaactttcct actatgtgaa tgacgggata ttaaaaccaa
    14641 tcggaaaaga gtacatcttt caagaactgg taaatcctat tcacaatcgt aaggataatc
    14701 aagtcacggt atcgctgaca gtggagtata tcgaccagca gaccaaagca acgcaggtat
    14761 ctcaatttga tttggtactt gaaaagaacg ggagtaattg gaagattata gaataacaaa
    14821 tattggtaca ttattacagc tattttgtaa tcacgtactc tctttgataa aaaattggag
    14881 attcctttac aaatatgctc ttatgtgcta ttatttaagt atctatttaa aaggagttaa
    14941 taaatatgcg gcaaggtatt cttaaataaa ctgtcaattt gatagtggaa acaaataatt
    15001 ggatgtcctt ttttaggagg gcttagtttt ttgtacccag tttaagaata cctttatcat
    15061 gtgattctaa agtatccgga gaatatctgt atgctttgta tgcctatggt tatgcataaa
    15121 aatcccagtg ataagagtat ttatcactgg gatttttatg cccttttggg cttttgaatg
    15181 gaggaaaatc acatgaaaat
//
LOCUS       DAVMJI010000126         6132 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 24F-HUB-12393 isolate
            24F-HUB-12393 SAMEA12277034-rid17919343.guided.060, whole genome
            shotgun sequence.
ACCESSION   DAVMJI010000126 DAVMJI010000000
VERSION     DAVMJI010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA12277034
            Sequence Read Archive: ERR7977583
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001719084.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001719084.1
            Genome Coverage       :: 75x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/04/2023 21:53:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,143
            CDSs (total)                      :: 2,101
            Genes (coding)                    :: 1,971
            CDSs (with protein)               :: 1,971
            Genes (RNA)                       :: 42
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 130
            CDSs (without protein)            :: 130
            Pseudo Genes (ambiguous residues) :: 0 of 130
            Pseudo Genes (frameshifted)       :: 63 of 130
            Pseudo Genes (incomplete)         :: 58 of 130
            Pseudo Genes (internal stop)      :: 40 of 130
            Pseudo Genes (multiple problems)  :: 26 of 130
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA12277034-rid17919343.guided.060"
                     /strain="24F-HUB-12393"
                     /serovar="24F"
                     /isolate="24F-HUB-12393"
                     /isolation_source="ARTICULAR LIQUID"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Spain"
                     /lat_lon="41.34531898 N 2.10435535 E"
                     /collection_date="2016-01-01"
     gene            33..1952
                     /gene="tet(M)"
                     /locus_tag="VYR58_002136"
     CDS             33..1952
                     /gene="tet(M)"
                     /locus_tag="VYR58_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEV3623206.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2071..2238
                     /locus_tag="VYR58_002137"
     CDS             2071..2238
                     /locus_tag="VYR58_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEV3623207.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(2298..2651)
                     /locus_tag="VYR58_002138"
     CDS             complement(2298..2651)
                     /locus_tag="VYR58_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV3623208.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            3156..3578
                     /locus_tag="VYR58_002139"
     CDS             3156..3578
                     /locus_tag="VYR58_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV3623209.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            3575..3805
                     /locus_tag="VYR58_002140"
     CDS             3575..3805
                     /locus_tag="VYR58_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV3623210.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            4266..4469
                     /locus_tag="VYR58_002141"
     CDS             4266..4469
                     /locus_tag="VYR58_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEV3623211.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            4551..5768
                     /locus_tag="VYR58_002142"
     CDS             4551..5768
                     /locus_tag="VYR58_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV3623212.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(5930..>6132)
                     /locus_tag="VYR58_002143"
     CDS             complement(5930..>6132)
                     /locus_tag="VYR58_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV3623213.1"
                     /translation="IRVALTSVLFALAHHPGTILAWCLYVSLGMFLGMVRYKSDLWGS
                     MGLHLVWNLLVYSLLLFNKNKV"
BASE COUNT         2128 a         1021 c         1213 g         1770 t
ORIGIN      
        1 cccttttggg cttttgaatg gaggaaaatc acatgaaaat tattaatatt ggagttttag
       61 ctcatgttga tgcgggaaaa actaccttaa cagaaagctt attatataac agtggagcga
      121 ttacagaatt aggaagcgtg gacagaggta caacgaaaac ggataatacg cttttagaac
      181 gtcagagagg aattacaatt cagacggcga taacctcttt tcagtggaaa aatactaaga
      241 taaacatcat agacacgcca ggacatatgg attttttagc agaagtatat cgttcattat
      301 cagtattaga tggggcaatt ctactgattt ctgcaaaaga tggcgtacaa gcacaaactc
      361 gtatattgtt tcatgcactt aggaaaatag gtattcccac aatctttttt atcaataaga
      421 ttgaccaaaa tggaattgat ttatcaacgg tttatcagga tattaaagag aaactttctg
      481 cggaaattgt aatcaaacag aaggtagaac tgcatcctaa tatgcgtgta atgaacttta
      541 ccgaatctga acaatgggat atggtaatag aaggaaatga ttaccttttg gagaaatata
      601 cgtctgggaa attattggaa gcattagaac tcgaacaaga ggaaagcata agatttcata
      661 attgttccct gttccctgtt tatcacggaa gtgcaaaaaa caatataggg attgataacc
      721 ttatagaagt gattacgaat aaattttatt catcaacaca tcgaggtcag tctgaacttt
      781 gcggaaaagt tttcaaaatt gagtattcgg aaaaaagaca gcgtcttgca tatatacgtc
      841 tttatagtgg cgtactgcat ttgcgagatt cggttagaat atcggaaaag gaaaaaataa
      901 aaattacaga aatgtatact tcaataaatg gtgaattatg taaaatcgat aaggcttatt
      961 ccggggaaat tgttattttg cagaatgagt ttttgaagtt aaatagtgtt cttggagata
     1021 caaagctatt gccacagaga gagagaattg aaaatcccct ccctctgctg caaacgactg
     1081 ttgaaccgag caaacctcaa caaagggaaa tgttacttga tgcactttta gaaatctccg
     1141 acagtgaccc gcttctgcga tattatgtgg attctgcgac acatgaaatc atactttctt
     1201 tcttagggaa agtacaaatg gaagtgactt gtgctctgct gcaagaaaag tatcatgtgg
     1261 agatagaaat aaaagagcct acagtcattt atatggaaag accgttaaaa aaagcagagt
     1321 ataccattca catcgaagtt ccaccgaatc ctttctgggc ttccattggt ctatctgtag
     1381 caccgcttcc attagggagc ggagtacagt atgagagctc ggtttctctt ggatacttaa
     1441 atcaatcgtt tcaaaatgca gttatggagg ggatacgcta tggctgtgaa caaggattgt
     1501 atggttggaa tgtgacggac tgtaaaatct gttttaagta tggcttatac tatagccctg
     1561 ttagtacccc agcagatttt cggatgcttg ctcctattgt attggaacaa gtcttaaaaa
     1621 aagctggaac agaattgtta gagccatatc ttagttttaa aatttatgcg ccacaggaat
     1681 atctttcacg agcatacaac gatgctccta aatattgtgc gaacatcgta gacactcaat
     1741 tgaaaaataa tgaggtcatt cttagtggag aaatccctgc tcggtgtatt caagaatatc
     1801 gtagtgattt aactttcttt acaaatggac gtagtgtttg tttaacagag ttaaaagggt
     1861 accatgttac taccggtgaa cctgtttgcc agccccgtcg tccaaatagt cggatagata
     1921 aagtacgata tatgttcaat aaaataactt agtgtatttt atgttgttat ataaatatgg
     1981 tttcttgtta aataagatga aatatttttt aataaagatt tgaattaaag tgtaaaggag
     2041 gagatagtta ttataaacta caagtggata ttgtgtcctg tatgtggaaa taaaacacga
     2101 ttaaagataa gggaagatac tgaattaaaa aaattccccc tctattgtcc gaaatgcaga
     2161 caagaaaatt taattgaaat aaagcagttc aaagtaactg tgattacaga gccagacgca
     2221 aagacgcaga gccgataaaa tgagattaat acaatctcat tttatcggct ctttccgtta
     2281 tgtatggatt cttttaatta gtcttcgatg tttcttgctt cgttgatacc gctggctaaa
     2341 gattccatta aggatagttc tttgtctgta aagctatcca tgtatttctc tatctgtaat
     2401 cgtcgggtgc tttttaccaa gttattagca ggtaagaaaa attcatcaac ggaaacatga
     2461 agtaacgata caaggtcata aagaacttgt atgctggggt gttgcccttt attttcaata
     2521 ttagttaagt accgtgggtc aatttcaatc aatgctccca cttgttcacg agttaaacct
     2581 cgtttcaatc gagcttcttt aatggctaaa ccaaaggctc taaaatcata tttatcttct
     2641 tttttacgca tagtagacca cctctataca ttttattgtt cctactgaat taaaaacagg
     2701 tatagaaaaa cgtgttatat ggtttatagg tttatattta ataaaaagca ctactaaacg
     2761 ccaataaaaa aaaccgttat atggtagtgc tatttacgct gttaaaatat tgtatattac
     2821 ttccaaatgg cggtttgttg gaggtcaacg tcgccatgaa gtacatcata tacaataaat
     2881 ttccttacat tgggttcttg tcaaaaaaag tcgtctatct gcaatagata agtacgtcca
     2941 ccaatgtggt tttataaatc atatagatag aataacagaa gcatgtaaac agagaaataa
     3001 atctgtttat atgctttttt ggctattcag aactttttta caaagtttat ttatcagtaa
     3061 tgcaacaaat ccccctttca cattgggact aagagtgaaa ggagataaac gagcaaggct
     3121 cacttccttt cctagacaga aagggggtga gaaacatgaa accatcttct tttcagacca
     3181 caatagaaaa tcagtttgac tatatctgta aacgtgctat ggaagacgag cgaaagaatt
     3241 atatgcttta tctttcaagg attgcaaagc gtgaggtgtc cttttcggat gttggcgatt
     3301 atcttgttag ccagtttgcg acaacagata actattcaac tgactttcag atttttacac
     3361 tcaatgggtt atcagtaggc gttgaaaatg atttgttgag tgaagcatta cgtgagttgc
     3421 cagacaagaa acgtgaaatt ctactgctgt tttactttat ggacatgagc gattcagaaa
     3481 ttgcagacct gttgaaattg aaccgttcta ctgtctatcg gcatagaacc agtggactag
     3541 ccttaattaa aaagtttatg gaggaatttg aagaatgaaa acacaatatc ctatgattcc
     3601 ctttcctctc attgtaaagg caacagatgg cgataccgaa gcgattaacc agattctaca
     3661 tcattacaga gggtacataa cgaagcgttc cctacgactt atgaaagatg aatatggcaa
     3721 tcaaagtatg gtcgttgatg aagtcttacg tggaagaatg gaaaccagac tgattacaaa
     3781 gattttgtca tttgaaatta agtaatatcc tctctccttt cgtggaagcg tgctaaacca
     3841 ttccacgctt cccgaacagg gaggtttgtt attccaccaa agcatattga gctttcaatg
     3901 tgttttgata ggctaacgag ccattgttct ttgaaaactg aataaaagta atcgaatacg
     3961 tttcgataag aaaagagcca acggaactaa ccgccatgac ctatcttata aagatagcga
     4021 gcgattcatg ttagtgatcc gagaagcaat ctttagcagg attgcctgca acgacattct
     4081 tatcgtgata atgatactcc catacagtca atagtccgag cgtgataaaa ccgtcgcagg
     4141 caatgagtat ggctacatga gaaccatgca ggggtggaac tcccgtgagc tttgctaaag
     4201 ctgttcgatt gctggtaaaa caacttttat gaaatccaaa taagtgattt ggaaaggagg
     4261 attttatgaa gcagactgac attcctattt gggaacgtta taccctaacc attgaagaag
     4321 cgtcaaaata ttttcgtatt ggcgaaaaca agctacgacg cttggcagag gaaaataaaa
     4381 atgcaaattg gctgattatg aatggcaatc gtattcagat taaacgaaaa caatttgaaa
     4441 aaattataga tacattggac gcaatctagc gtcgccaaag ggtcttgtat atgataaaat
     4501 agtattaagt cgtatcaagg ctctttccat aaaggaaagg agcaaatgcc atgtcagaaa
     4561 aaagacgtga caataaaggt cgaatcttaa agactggaga gagccaacga aaagacggaa
     4621 gatacttata caaatatata gattcatttg gagaaccgca atttgtttac tcgtggaaac
     4681 ttgtggctac agaccgagta ccagcaggaa agcgtgattg tatctcactt agagagaaaa
     4741 tcgcagagtt acagaaagac attcatgatg gtattgatgt tgtaggaaag aaaatgacac
     4801 tctgccagct ttacgcaaaa cagaacgctc aaagaccaaa ggttagaaaa aacactgaaa
     4861 ctggacgcaa atatcttatg gatattttga agaaagacaa gttaggtgta agaagtattg
     4921 acagtattaa gccatcagac gctaaagaat gggctattag aatgagtgaa aatggttatg
     4981 cttatcaaac catcaataac tacaaacgtt ctttaaaggc ttcattctat attgctatac
     5041 aagatgattg tgttcggaag aatccatttg actttcaact gaaagcagtt cttgatgatg
     5101 atactgtccc taagaccgta ctaacagaag aacaggaaga aaaactgtta gcctttgcaa
     5161 aagctgataa aacctacagc aaaaattatg atgaaattct gatactctta aaaacaggtc
     5221 ttcgtatttc agagtttggt ggtttgacac ttccagattt agattttgag aatcgtcttg
     5281 tcaatataga ccatcagcta ttgagagata ctgaaattgg gtactacatt gaaacaccaa
     5341 agaccaaaag tggcgaacgt caagttccta tggttgaaga agcctatcaa gcatttaagc
     5401 gagtgttagc gaatcgaaag aatgataagc gtgttgagat tgatggatat agtgatttcc
     5461 tctttcttaa tagaaagaac tatccaaaag tggcaagtga ttacaacggc atgatgaaag
     5521 gtcttgttaa gaaatacaat aagtataacg aggataaatt gccacacatc actccacata
     5581 gtttgcgaca tacattctgt accaactatg caaatgcagg aatgaatcca aaggcattac
     5641 agtacattat gggacatgct aatatagcca tgacgctgaa ctattacgca catgcaacat
     5701 tcgattctgc aatggcagaa atgaaacgct tgaataaaga gaagcaacag gagcgtcttg
     5761 ttgcttagta gtacaaatga atttactact tatttaccac ttctgacagc taagacatga
     5821 ggaaatatgc aaagaaacgt gaagtatctt cctacagtaa aaatactcga aagcacatag
     5881 aataaggctt tacgagcatt taagaaaata taaaaagata attagaaatt tatactttgt
     5941 ttttattaaa aagcagcaaa ctataaacta gtaggttcca cactaaatgt agccccatac
     6001 tgccccacaa gtccgattta tagcgtacca tccctaaaaa cattcccaat gaaacatata
     6061 aacaccaagc tagaatggtt cctggatgat gagctaaggc aaataaaaca cttgtcaaag
     6121 caactcgaat at
//
